Methodological Guidelines to Study Extracellular Vesicles

Coumans, FAW; Brisson, AR; Buzas, EI [Buzás, Edit Irén (Immunbiológia), szerző] Genetikai, Sejt- és Immunbiológiai Intézet (SE / AOK / I); Dignat-George, F; Drees, EEE; El-Andaloussi, S; Emanueli, C; Gasecka, A; Hendrix, A; Hill, AF; Lacroix, R; Lee, Y; van Leeuwen, TG; Mackman, N; Mager, I; Nolan, JP; van der Pol, E; Pegtel, DM; Sahoo, S; Siljander, PRM; Sturk, G; de Wever, O; Nieuwland, R ✉

Angol nyelvű Összefoglaló cikk (Folyóiratcikk) Tudományos
Megjelent: CIRCULATION RESEARCH 0009-7330 1524-4571 120 (10) pp. 1632-1648 2017
  • SJR Scopus - Cardiology and Cardiovascular Medicine: D1
  • Általános orvostudomány
  • Biológiai tudományok
  • Klinikai orvostan
Owing to the relationship between extracellular vesicles (EVs) and physiological and pathological conditions, the interest in EVs is exponentially growing. EVs hold high hopes for novel diagnostic and translational discoveries. This review provides an expert-based update of recent advances in the methods to study EVs and summarizes currently accepted considerations and recommendations from sample collection to isolation, detection, and characterization of EVs. Common misconceptions and methodological pitfalls are highlighted. Although EVs are found in all body fluids, in this review, we will focus on EVs from human blood, not only our most complex but also the most interesting body fluid for cardiovascular research.
Hivatkozás stílusok: IEEEACMAPAChicagoHarvardCSLMásolásNyomtatás
2024-07-14 19:03