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Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide that exerts general cytoprotective effects, including protection in different kidney disorders. The aim of our study was to investigate the ischemia/reperfusion-induced kidney injury of male and female rats to confirm the protective effects of PACAP in the kidney and to reveal possible gender differences.Male and female Wistar rats underwent unilateral renal artery clamping followed by 24-h, 48-h, or 14-day reperfusion. PACAP was administered intravenously before arterial clamping in half of the rats. Tubular damage, cytokine expression pattern, oxidative stress marker, antioxidative status and signaling pathways were evaluated using histology, immunohistology, cytokine array, PCR, and Western blot. Tubular damage was significantly less severe in the PACAP-treated male and female rats compared to controls. Results of female animals were significantly better in both treated and untreated groups. Cytokine expression, oxidative stress marker and antioxidative status confirmed the histological results. We also revealed that PACAP counteracted the decreased PKA phosphorylation, influenced the expression of BMP2 and BMP4, and increased the expression of the protein Smad1.We conclude that PACAP is protective in ischemia/reperfusion-induced kidney injury in both sexes, but females had markedly less pronounced injury after ischemia/reperfusion, possibly also involving further protective factors, the investigation of which could have future therapeutic value in treating ischemic kidney injuries.
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Anatómiai Intézet (PTE / ÁOK); Anatómiai, Szövet- és Fejlődéstani Intézet (DE / ÁOK); Biokémiai és Orvosi Kémiai Intézet (PTE / ÁOK); MTA-PTE PACAP Kutatócsoport (PTE / KCS); Sebészeti Klinika (PTE / ÁOK); Sebészeti Oktató és Kutató Intézet (PTE / ÁOK)
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10040816"> <a href="/gui2/?type=authors&mode=browse&sel=10040816" target="_blank">Laszlo, Eszter</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10034606"> <a href="/gui2/?type=authors&mode=browse&sel=10034606" target="_blank">Juhasz, Tamas</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10047779"> <a href="/gui2/?type=authors&mode=browse&sel=10047779" target="_blank">Varga, Adam</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Czibere, Bernadett </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10014558"> <a href="/gui2/?type=authors&mode=browse&sel=10014558" target="_blank">Kovacs, Krisztina</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Degrell, Peter </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016482"> <a href="/gui2/?type=authors&mode=browse&sel=10016482" target="_blank">Horvath, Gabriella ✉</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10021392"> <a href="/gui2/?type=authors&mode=browse&sel=10021392" target="_blank">Jancso, Gabor</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016614"> <a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakaly, Peter</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10013006"> <a href="/gui2/?type=authors&mode=browse&sel=10013006" target="_blank">Tamas, Andrea</a> </span> <span class="author-type"> </span> et al. </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;30321888" mtid="30321888" target="_blank">Protective Effect of PACAP on Ischemia/Reperfusion-Induced Kidney Injury of Male and Female Rats : Gender Differences</a></div> <div class="pub-info"> <span class="journal-title">JOURNAL OF MOLECULAR NEUROSCIENCE</span> <span class="journal-volume">68</span> : <span class="journal-issue">3</span> <span class="page"> pp. 408-419. , 12 p. </span> <span class="year">(2019)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Fizetős "> <a style="color:blue" title="10.1007/s12031-018-1207-y" target="_blank" href="https://doi.org/10.1007/s12031-018-1207-y"> DOI </a> </span> <span class="id identifier oa_CLOSED" title=" Zárt "> <a style="color:black" title="99181" target="_blank" href="http://real.mtak.hu/99181"> REAL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000472082700009" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000472082700009"> WoS </a> </span> <span class="id identifier oa_CLOSED" title=" Zárt "> <a style="color:blue" title="259468" target="_blank" href="http://hdl.handle.net/2437/259468"> DEA </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85056783275" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85056783275"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="30443839" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30443839&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="deleted-record">Zárolt</span> <span class="short-pub-mtid"> Közlemény:30321888 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core">Forrás Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 17</span> | Független: 7 | Függő: 10 | Nem jelölt: 0 | WoS jelölt: 17 | Scopus jelölt: 17 | WoS/Scopus jelölt: 17 | DOI jelölt: 17 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10040816"><a href="/gui2/?type=authors&mode=browse&sel=10040816" target="_blank">Laszlo Eszter (<span class="authorship-author-name">László Eszter</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Anatómiai Intézet; <span title="Pécsi Tudományegyetem">PTE</span>/<span title="Kutatócsoportok">KCS</span>/MTA-PTE PACAP Kutatócsoport</span> ; <span class="author-name" mtid="10034606"><a href="/gui2/?type=authors&mode=browse&sel=10034606" target="_blank">Juhasz Tamas (<span class="authorship-author-name">Juhász Tamás</span> <span class="authorAux-mtmt"> molekuláris biológia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Anatómiai, Szövet- és Fejlődéstani Intézet</span> ; <span class="author-name" mtid="10047779"><a href="/gui2/?type=authors&mode=browse&sel=10047779" target="_blank">Varga Adam (<span class="authorship-author-name">Varga Ádám</span> <span class="authorAux-mtmt"> Sebészet</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> ; <span class="author-name" >Czibere Bernadett </span> ; <span class="author-name" mtid="10014558"><a href="/gui2/?type=authors&mode=browse&sel=10014558" target="_blank">Kovacs Krisztina (<span class="authorship-author-name">Kovács Krisztina</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Biokémiai és Orvosi Kémiai Intézet</span> ; <span class="author-name" >Degrell Peter </span> ; <span class="author-name" mtid="10016482"><a href="/gui2/?type=authors&mode=browse&sel=10016482" target="_blank">Horvath Gabriella ✉ (<span class="authorship-author-name">Horváth-Opper Gabriella</span> <span class="authorAux-mtmt"> Anatómia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Anatómiai Intézet; <span title="Pécsi Tudományegyetem">PTE</span>/<span title="Kutatócsoportok">KCS</span>/MTA-PTE PACAP Kutatócsoport</span> ; <span class="author-name" mtid="10021392"><a href="/gui2/?type=authors&mode=browse&sel=10021392" target="_blank">Jancso Gabor (<span class="authorship-author-name">Jancsó Gábor</span> <span class="authorAux-mtmt"> Érsebészet - Vascular surgery</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Oktató és Kutató Intézet</span> ; <span class="author-name" mtid="10016614"><a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakaly Peter (<span class="authorship-author-name">Szakály Péter</span> <span class="authorAux-mtmt"> Sebészet</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> ; <span class="author-name" mtid="10013006"><a href="/gui2/?type=authors&mode=browse&sel=10013006" target="_blank">Tamas Andrea (<span class="authorship-author-name">Tamás Andrea</span> <span class="authorAux-mtmt"> Idegtudomány</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Anatómiai Intézet; <span title="Pécsi Tudományegyetem">PTE</span>/<span title="Kutatócsoportok">KCS</span>/MTA-PTE PACAP Kutatócsoport</span> ; <span class="author-name" mtid="10001467"><a href="/gui2/?type=authors&mode=browse&sel=10001467" target="_blank">Reglodi Dora (<span class="authorship-author-name">Reglődi Dóra</span> <span class="authorAux-mtmt"> Idegtudományok</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Anatómiai Intézet; <span title="Pécsi Tudományegyetem">PTE</span>/<span title="Kutatócsoportok">KCS</span>/MTA-PTE PACAP Kutatócsoport</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;30321888" target="_blank">Protective Effect of PACAP on Ischemia/Reperfusion-Induced Kidney Injury of Male and Female Rats : Gender Differences</a></div> <div> <span class="journal-title">JOURNAL OF MOLECULAR NEUROSCIENCE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0895-8696">0895-8696</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1559-1166">1559-1166</a>)</span>: <span class="journal-volume">68</span> <span class="journal-issue">3</span> <span class="page"> pp 408-419 </span> <span class="year">(2019)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Fizetős "> <a style="color:blue" title="10.1007/s12031-018-1207-y" target="_blank" href="https://doi.org/10.1007/s12031-018-1207-y"> DOI </a> </span> <span class="id identifier oa_CLOSED" title=" Zárt "> <a style="color:black" title="99181" target="_blank" href="http://real.mtak.hu/99181"> REAL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000472082700009" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000472082700009"> WoS </a> </span> <span class="id identifier oa_CLOSED" title=" Zárt "> <a style="color:blue" title="259468" target="_blank" href="http://hdl.handle.net/2437/259468"> DEA </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85056783275" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85056783275"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="30443839" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30443839&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 17</span> | Független: 7 | Függő: 10 | Nem jelölt: 0 | WoS jelölt: 17 | Scopus jelölt: 17 | WoS/Scopus jelölt: 17 | DOI jelölt: 17 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;30321888&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 21 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 30321888</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">PubMed (pubmed_result.xml, 2018-11-20)</span> </div> <div class="funder"> Az orvos-, egészségtudományi- és gyógyszerészképzés tudományos műhelyeinek fejlesztése(EFOP-3.6.3-VEKOP-16-2017-00009) Támogató: EFOP-VEKOP </div> <div class="notDuplums"><a target="_blank" href="/api/publication/30321888/notduplums">38 Nem duplumnak jelölés</a> </div> <div class="lastModified">Utolsó módosítás: 2023.10.27. 08:45 Milánkovics Róbert (PTE ÁOK admin 4) </div> <div class="lockedBy">Ideiglenesen zárolva 2023.11.07. 10:01 Pécsi Éva (MTMT Közp 3, admin) </div> </div></div>
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Drug-induced immunosuppression can predispose kidney transplant patients to different complications including chronic infections and oral lesions. We surveyed oral hygiene habits and conducted detailed periodontal examinations for status assessment. Appropriate oral hygiene and regular professional control can reduce number and severity of complications, which might be preventive for transplant rejection.
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Schönfeld, B </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10047779"> <a href="/gui2/?type=authors&mode=browse&sel=10047779" target="_blank">Varga, Á</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016614"> <a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakály, P</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016415"> <a href="/gui2/?type=authors&mode=browse&sel=10016415" target="_blank">Bán, Á ✉</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;30681304" mtid="30681304" target="_blank">Oral Health Status of Kidney Transplant Patients</a></div> <div class="pub-info"> <span class="journal-title">TRANSPLANTATION PROCEEDINGS</span> <span class="journal-volume">51</span> : <span class="journal-issue">4</span> <span class="page"> pp. 1248-1250. , 3 p. </span> <span class="year">(2019)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Fizetős "> <a style="color:blue" title="10.1016/j.transproceed.2019.03.009" target="_blank" href="https://doi.org/10.1016/j.transproceed.2019.03.009"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000500179300052" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000500179300052"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85065587630" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85065587630"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="31101207" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=31101207&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:30681304 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core">Forrás Idéző </span> <span class="pub-type">Folyóiratcikk (Rövid közlemény ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 5</span> | Független: 4 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 5 | Scopus jelölt: 5 | WoS/Scopus jelölt: 5 | DOI jelölt: 5 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Schönfeld B </span> ; 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Takrolimuszterápia vesetranszplantáció után : A koncentráció/dózis arány aktuális kérdései
Tacrolimus therapy after renal transplantation. Current questions of concentration/dose ratio
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Tacrolimus is an important part of immunosuppressive therapy after solid organ transplantation. The therapeutic range of the drug from the calcineurin inhibitor group is narrow. Adjustment of the blood concentration can be very complicated but to be able to avoid the occurrence of side effects or ineffective immunosuppression it is inevitable. This article summarizes the properties of tacrolimus pharmacokinetics, pharmacogenetics and pharmacodynamics. We will focus on individual variations of cytochrome enzymes. In the following part, a new method for screening high risk patients will be introduced. We will present the publications of the determination of the concentration/dose (C/D) ratio. By determining the C/D ratio, researchers identify fast and slow metabolizing patient groups. Fast metabolizers require higher doses in general and the occurrence of complications is also more frequent in this group. Long-term results are lagging behind the slow metabolizing group. The long-term results of renal transplantation nowadays contribute to the postoperative period and the later years rather than the surgery itself. It includes the proper management of previous illnesses (e.g., hypertension, diabetes, endocrinological problems), detection of complications (e.g., infections, malignancies), and the precise regulation of immunosuppressive therapy. Orv Hetil. 2019; 160(30): 1178-1183.
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10047779"> <a href="/gui2/?type=authors&mode=browse&sel=10047779" target="_blank">Varga, Ádám ✉</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Kalmár Nagy, Károly </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016614"> <a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakály, Péter</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;30745449" mtid="30745449" target="_blank">Takrolimuszterápia vesetranszplantáció után : A koncentráció/dózis arány aktuális kérdései</a></div> <div class="pub-info"> <span class="journal-title">ORVOSI HETILAP</span> <span class="journal-volume">160</span> : <span class="journal-issue">30</span> <span class="page"> pp. 1178-1183. , 6 p. </span> <span class="year">(2019)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1556/650.2019.31470" target="_blank" href="https://doi.org/10.1556/650.2019.31470"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000476619200002" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000476619200002"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85074118672" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85074118672"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="31327249" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=31327249&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:30745449 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core">Forrás </span> <span class="pub-type">Folyóiratcikk (Összefoglaló cikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 1 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 1 | Scopus jelölt: 1 | WoS/Scopus jelölt: 1 | DOI jelölt: 1 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10047779"><a href="/gui2/?type=authors&mode=browse&sel=10047779" target="_blank">Varga Ádám ✉ (<span class="authorship-author-name">Varga Ádám</span> <span class="authorAux-mtmt"> Sebészet</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> ; <span class="author-name" >Kalmár Nagy Károly </span> ; <span class="author-name" mtid="10016614"><a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakály Péter (<span class="authorship-author-name">Szakály Péter</span> <span class="authorAux-mtmt"> Sebészet</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;30745449" target="_blank">Takrolimuszterápia vesetranszplantáció után : A koncentráció/dózis arány aktuális kérdései</a></div> <div> <span class="journal-title">ORVOSI HETILAP</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0030-6002">0030-6002</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1788-6120">1788-6120</a>)</span>: <span class="journal-volume">160</span> <span class="journal-issue">30</span> <span class="page"> pp 1178-1183 </span> <span class="year">(2019)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Magyar | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1556/650.2019.31470" target="_blank" href="https://doi.org/10.1556/650.2019.31470"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000476619200002" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000476619200002"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85074118672" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85074118672"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="31327249" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=31327249&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 1 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 1 | Scopus jelölt: 1 | WoS/Scopus jelölt: 1 | DOI jelölt: 1 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 30745449</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">PubMed (pubmed_result.xml, 2019-07-23)</span> </div> <div class="lastModified">Utolsó módosítás: 2023.06.23. 11:44 Milánkovics Róbert (PTE ÁOK admin 4) </div> </div></div>
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Diabetes increases the risk of different kidney diseases. The most important is diabetic nephropathy, however, ischemic kidney disease, chronic pyleonephritis and papilla necrosis may also develop. The prognosis of diabetic nephropathy has improved recently, however, it is still the primary cause of dialysis and transplantation. Cardiovascular diseases predict mostly mortality in diabetic patients, however, cerebrovascular insults and peripheral obstructive arterial diseases necessitating lower limb amputations are also important. Diabetic retinopathy is almost always present with diabetic nephropathy. Diabetic neuropathy may also develop, furthermore vascular complications often combine. All these urge complex workup, follow-up and early treatment. If transplantation is indicated, preemptive operation should be preferred, and living donation shows the best outcomes. Different forms of carbohydrate disorder may occur after transplantation: new-onset diabetes or diabetes known before transplantation may progress. Renal transplantation with pancreas transplantation may be indicated in type 1 diabetes with end-stage diabetic nephropathy, most often simultaneously. This may result in normoglycemia and insulin-independence and the progression of other complications may also halt. Transplant associated hyperglycemia occurs in most of the patients early, however, it is often transitory. Despite stabilization of the patient and of the immunosuppressive therapy, about one third of the patients may develop posttransplant diabetes. Insulin secretion disorder is the primary cause, but insulin resistance is also needed. Insulin administration may help, however, other antidiabetics can also be useful. Carbohydrate metabolism should be checked in both cadaveric and living donors. The authors make an attempt to summarize the above conditions with Hungarian relevance as well. Orv Hetil. 2018; 159(46): 1930-1939.
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10020375"> <a href="/gui2/?type=authors&mode=browse&sel=10020375" target="_blank">Wagner, László ✉</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016656"> <a href="/gui2/?type=authors&mode=browse&sel=10016656" target="_blank">Wittmann, István</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10024125"> <a href="/gui2/?type=authors&mode=browse&sel=10024125" target="_blank">Piros, László</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10065964"> <a href="/gui2/?type=authors&mode=browse&sel=10065964" target="_blank">P Szabó, Réka</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016614"> <a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakály, Péter</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;30323026" mtid="30323026" target="_blank">Diabetológia és szervátültetés [Diabetology and solid organ transplantation]</a></div> <div class="pub-info"> <span class="journal-title">ORVOSI HETILAP</span> <span class="journal-volume">159</span> : <span class="journal-issue">46</span> <span class="page"> pp. 1930-1939. , 10 p. </span> <span class="year">(2018)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1556/650.2018.31281" target="_blank" href="https://doi.org/10.1556/650.2018.31281"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000450373500010" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000450373500010"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85056739633" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85056739633"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="30450927" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30450927&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_NONE" title=" Nincs "> <a style="color:blue" title="https://m2.mtmt.hu/api/publication/32109605" target="_blank" href="https://m2.mtmt.hu/api/publication/32109605"> Egyéb URL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="2788024" target="_blank" href="http://www.matarka.hu/egy-kozlemeny-oldala.php?MatarkaID=2788024"> Matarka </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="131727" target="_blank" href="https://mob.aeek.hu/detailsperm.jsp?PERMID=131727"> MOB </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:30323026 </span> <span class="status-holder"><span class="status-data status-APPROVED"> Nyilvános </span></span> <span class="pub-core">Forrás Idéző </span> <span class="pub-type">Folyóiratcikk (Összefoglaló cikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 0 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 1 | Scopus jelölt: 1 | WoS/Scopus jelölt: 1 | DOI jelölt: 1 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10020375"><a href="/gui2/?type=authors&mode=browse&sel=10020375" target="_blank">Wagner László ✉ (<span class="authorship-author-name">Wágner László József</span> <span class="authorAux-mtmt"> Transzplantáció</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Transzplantációs és Sebészeti Klinika</span> ; <span class="author-name" mtid="10016656"><a href="/gui2/?type=authors&mode=browse&sel=10016656" target="_blank">Wittmann István (<span class="authorship-author-name">Wittmann István</span> <span class="authorAux-mtmt"> Klinikai orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/II.sz. Belgyógyászati Klinika és Nephrológiai Centrum</span> ; <span class="author-name" mtid="10024125"><a href="/gui2/?type=authors&mode=browse&sel=10024125" target="_blank">Piros László (<span class="authorship-author-name">Piros László</span> <span class="authorAux-mtmt"> sebészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Transzplantációs és Sebészeti Klinika</span> ; <span class="author-name" mtid="10065964"><a href="/gui2/?type=authors&mode=browse&sel=10065964" target="_blank">P Szabó Réka (<span class="authorship-author-name">P. Szabó Réka</span> <span class="authorAux-mtmt"> nephrológia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Belgyógyászati Intézet</span> ; <span class="author-name" mtid="10016614"><a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakály Péter (<span class="authorship-author-name">Szakály Péter</span> <span class="authorAux-mtmt"> Sebészet</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;30323026" target="_blank">Diabetológia és szervátültetés [Diabetology and solid organ transplantation]</a></div> <div> <span class="journal-title">ORVOSI HETILAP</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0030-6002">0030-6002</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1788-6120">1788-6120</a>)</span>: <span class="journal-volume">159</span> <span class="journal-issue">46</span> <span class="page"> pp 1930-1939 </span> <span class="year">(2018)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Magyar | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1556/650.2018.31281" target="_blank" href="https://doi.org/10.1556/650.2018.31281"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000450373500010" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000450373500010"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85056739633" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85056739633"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="30450927" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30450927&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_NONE" title=" Nincs "> <a style="color:blue" title="https://m2.mtmt.hu/api/publication/32109605" target="_blank" href="https://m2.mtmt.hu/api/publication/32109605"> Egyéb URL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="2788024" target="_blank" href="http://www.matarka.hu/egy-kozlemeny-oldala.php?MatarkaID=2788024"> Matarka </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="131727" target="_blank" href="https://mob.aeek.hu/detailsperm.jsp?PERMID=131727"> MOB </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 0 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 1 | Scopus jelölt: 1 | WoS/Scopus jelölt: 1 | DOI jelölt: 1 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;30323026&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 4 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 30323026</span> | <span class="status-data status-APPROVED"> Nyilvános </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">PubMed (pubmed_result.xml, 2018-11-21)</span> </div> <div class="lastModified">Utolsó módosítás: 2023.09.26. 09:48 Szendrei László (DE/BTK admin5) </div> </div></div>
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10020375"> <a href="/gui2/?type=authors&mode=browse&sel=10020375" target="_blank">Wágner, László ✉</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Kalmár-Nagy, Károly </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10024126"> <a href="/gui2/?type=authors&mode=browse&sel=10024126" target="_blank">Toronyi, Éva</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10024144"> <a href="/gui2/?type=authors&mode=browse&sel=10024144" target="_blank">Török, Szilárd</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10024162"> <a href="/gui2/?type=authors&mode=browse&sel=10024162" target="_blank">Patonai, Attila</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016614"> <a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakály, Péter</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;3343716" mtid="3343716" target="_blank">De novo vesetranszplantált betegek mikofenolat-mofetilt tartalmazó immunszuppresszív kombinációs kezelésével kapcsolatban szerzett hazai tapasztalatok - ORANGE vizsgálat</a></div> <div class="pub-info"> <span class="journal-title">HYPERTONIA ÉS NEPHROLOGIA</span> <span class="journal-volume">22</span> : <span class="journal-issue">1</span> <span class="page"> pp. 6-9. , 4 p. </span> <span class="year">(2018)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="http://elitmed.hu/kiadvanyaink/hypertonia-es-nephrologia/de-novo-vesetranszplantalt-betegek-mikofenolat-mofetilt-tartalmazo-immunszuppressziv-kombinacios-kezelesevel-kapcsolatban-szerzett-hazai-tapasztalatok/" target="_blank" href="http://elitmed.hu/kiadvanyaink/hypertonia-es-nephrologia/de-novo-vesetranszplantalt-betegek-mikofenolat-mofetilt-tartalmazo-immunszuppressziv-kombinacios-kezelesevel-kapcsolatban-szerzett-hazai-tapasztalatok/"> Kiadónál </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="11428/1/H%26N_2018_1.pdf#page=6" target="_blank" href="http://real-j.mtak.hu/11428/1/H%26N_2018_1.pdf#page=6"> REAL-J </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:3343716 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core">Forrás </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10020375"><a href="/gui2/?type=authors&mode=browse&sel=10020375" target="_blank">Wágner László ✉ (<span class="authorship-author-name">Wágner László József</span> <span class="authorAux-mtmt"> Transzplantáció</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Transzplantációs és Sebészeti Klinika</span> ; <span class="author-name" >Kalmár-Nagy Károly </span> ; <span class="author-name" mtid="10024126"><a href="/gui2/?type=authors&mode=browse&sel=10024126" target="_blank">Toronyi Éva (<span class="authorship-author-name">Toronyi Éva</span> <span class="authorAux-mtmt"> Sebészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Transzplantációs és Sebészeti Klinika</span> ; <span class="author-name" mtid="10024144"><a href="/gui2/?type=authors&mode=browse&sel=10024144" target="_blank">Török Szilárd (<span class="authorship-author-name">Török Szilárd</span> <span class="authorAux-mtmt"> belgyógyászat, nefrológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Transzplantációs és Sebészeti Klinika</span> ; <span class="author-name" mtid="10024162"><a href="/gui2/?type=authors&mode=browse&sel=10024162" target="_blank">Patonai Attila (<span class="authorship-author-name">Patonai Attila</span> <span class="authorAux-mtmt"> belgyógyászat, patológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Transzplantációs és Sebészeti Klinika</span> ; <span class="author-name" mtid="10016614"><a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakály Péter (<span class="authorship-author-name">Szakály Péter</span> <span class="authorAux-mtmt"> Sebészet</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;3343716" target="_blank">De novo vesetranszplantált betegek mikofenolat-mofetilt tartalmazó immunszuppresszív kombinációs kezelésével kapcsolatban szerzett hazai tapasztalatok - ORANGE vizsgálat</a></div> <div> <span class="journal-title">HYPERTONIA ÉS NEPHROLOGIA</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1418-477X">1418-477X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2498-6259">2498-6259</a>)</span>: <span class="journal-volume">22</span> <span class="journal-issue">1</span> <span class="page"> pp 6-9 </span> <span class="year">(2018)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Magyar | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="http://elitmed.hu/kiadvanyaink/hypertonia-es-nephrologia/de-novo-vesetranszplantalt-betegek-mikofenolat-mofetilt-tartalmazo-immunszuppressziv-kombinacios-kezelesevel-kapcsolatban-szerzett-hazai-tapasztalatok/" target="_blank" href="http://elitmed.hu/kiadvanyaink/hypertonia-es-nephrologia/de-novo-vesetranszplantalt-betegek-mikofenolat-mofetilt-tartalmazo-immunszuppressziv-kombinacios-kezelesevel-kapcsolatban-szerzett-hazai-tapasztalatok/"> Kiadónál </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="11428/1/H%26N_2018_1.pdf#page=6" target="_blank" href="http://real-j.mtak.hu/11428/1/H%26N_2018_1.pdf#page=6"> REAL-J </a> </span> </span> <div class="mtid"><span class="long-pub-mtid">Közlemény: 3343716</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 3343716</span> | Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2022.09.19. 19:17 Berhidi Anna (SE_ÁOK_Sebészet_Admin5_BA, admin) </div> </div></div>
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Correspondence Address: Varga, A.; Department of Surgery, H-7624 Pecs, Ifjusag u 13, Hungary; email: advarga88@gmail.com
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10054037"> <a href="/gui2/?type=authors&mode=browse&sel=10054037" target="_blank">Praksch, D</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10025798"> <a href="/gui2/?type=authors&mode=browse&sel=10025798" target="_blank">Sandor, B</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Nagy, KK </span> <span class="author-type"> </span> ; <span class="author-name" > Viola, M </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10029477"> <a href="/gui2/?type=authors&mode=browse&sel=10029477" target="_blank">Toth, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10004892"> <a href="/gui2/?type=authors&mode=browse&sel=10004892" target="_blank">Toth, K</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016614"> <a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakaly, P</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10047779"> <a href="/gui2/?type=authors&mode=browse&sel=10047779" target="_blank">Varga, A ✉</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;3124878" mtid="3124878" target="_blank">Acetylsalicylic Acid Resistance After Simultaneous Pancreas-Kidney Transplantation</a></div> <div class="pub-info"> <span class="journal-title">TRANSPLANTATION PROCEEDINGS</span> <span class="journal-volume">48</span> : <span class="journal-issue">7</span> <span class="page"> pp. 2555-2557. , 3 p. </span> <span class="year">(2016)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Fizetős "> <a style="color:blue" title="10.1016/j.transproceed.2016.07.008" target="_blank" href="https://doi.org/10.1016/j.transproceed.2016.07.008"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000386317900077" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000386317900077"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84992349862" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84992349862"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="27742347" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=27742347&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:3124878 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core">Forrás Idéző </span> <span class="pub-type">Folyóiratcikk (Rövid közlemény ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
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<img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png">
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<div class="autype autype0"> <span class="author-name" mtid="10054037"><a
href="/gui2/?type=authors&mode=browse&sel=10054037" target="_blank">Praksch D
(<span class="authorship-author-name">Praksch Dóra</span>
<span class="authorAux-mtmt"> PhD hallgató</span>)
</a>
</span>
<span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/I.sz. Belgyógyászati Klinika</span>
;
<span class="author-name" mtid="10025798"><a
href="/gui2/?type=authors&mode=browse&sel=10025798" target="_blank">Sandor B
(<span class="authorship-author-name">Sándor Barbara</span>
<span class="authorAux-mtmt"> Kardiológia, kardiológiai rehabilitáció</span>)
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<span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/I.sz. Belgyógyászati Klinika</span>
;
<span class="author-name" >Nagy KK
</span>
;
<span class="author-name" >Viola M
</span>
;
<span class="author-name" mtid="10029477"><a
href="/gui2/?type=authors&mode=browse&sel=10029477" target="_blank">Toth A
(<span class="authorship-author-name">Tóth András</span>
<span class="authorAux-mtmt"> Haemorheologia-radiológia</span>)
</a>
</span>
<span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/I.sz. Belgyógyászati Klinika</span>
;
<span class="author-name" mtid="10004892"><a
href="/gui2/?type=authors&mode=browse&sel=10004892" target="_blank">Toth K
(<span class="authorship-author-name">Tóth Kálmán</span>
<span class="authorAux-mtmt"> Cardiologia-haemorheologia</span>)
</a>
</span>
<span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/I.sz. Belgyógyászati Klinika</span>
;
<span class="author-name" mtid="10016614"><a
href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakaly P
(<span class="authorship-author-name">Szakály Péter</span>
<span class="authorAux-mtmt"> Sebészet</span>)
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</span>
<span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span>
;
<span class="author-name" mtid="10047779"><a
href="/gui2/?type=authors&mode=browse&sel=10047779" target="_blank">Varga A ✉
(<span class="authorship-author-name">Varga Ádám</span>
<span class="authorAux-mtmt"> Sebészet</span>)
</a>
</span>
<span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;3124878" target="_blank">Acetylsalicylic Acid Resistance After Simultaneous Pancreas-Kidney Transplantation</a></div> <div> <span class="journal-title">TRANSPLANTATION PROCEEDINGS</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0041-1345">0041-1345</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1873-2623">1873-2623</a>)</span>:
<span class="journal-volume">48</span> <span class="journal-issue">7</span>
<span class="page">
pp 2555-2557
</span> <span class="year">(2016)</span>
<div class="conference">
17th Congress of the Hungarian Transplantation Society.
</div>
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<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Nyelv:
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<pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: First Department of Medicine, Medical School, University of Pecs, Pecs, Hungary
Department of Surgery, Medical School, University of Pecs, Pecs, Hungary
Export Date: 26 October 2023
CODEN: TRPPA
Correspondence Address: Varga, A.; Department of Surgery, H-7624 Pecs, Ifjusag u 13, Hungary; email: advar...</pre>
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Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide with very diverse distribution and functions. Among others, PACAP is a potent cytoprotective peptide due to its antiapoptotic, anti-inflammatory, and antioxidant actions. This also has been shown in different kidney pathologies, including ischemia/reperfusion-induced kidney injury. Similar protective effects of the endogenous PACAP are confirmed by the increased vulnerability of PACAP-deficient mice to different harmful stimuli. Kidneys of homozygous PACAP-deficient mice have more severe damages in renal ischemia/reperfusion and kidney cell cultures isolated from these mice show increased sensitivity to renal oxidative stress. In our present study we raised the question of whether the partial lack of the PACAP gene is also deleterious, i.e. whether heterozygous PACAP-deficient mice also display more severe damage after renal ischemia/reperfusion. Mice underwent 45 or 60 minutes of ischemia followed by 2 weeks reperfusion. Histological evaluation of the kidneys was performed and individual histopathological parameters were graded. Furthermore, we investigated apoptotic markers, cytokine expression, and the activity of superoxide dismutase (SOD) enzyme 24 hours after 60 minutes of renal ischemia/reperfusion. We found no difference between the intact kidneys of wild-type and heterozygous mice, but marked differences could be observed following ischemia/reperfusion. Heterozygous PACAP-deficient mice had more severe histological alterations, with significantly higher histopathological scores for most of the tested parameters. Higher level of the proapoptotic pp38 MAPK and of some proinflammatory cytokines, as well as lower activity of the antioxidant SOD could be found in these mice. In conclusion, the partial lack of the PACAP gene results in worse outcomes in cases of renal ischemia/reperfusion, confirming that PACAP functions as an endogenous protective factor in the kidney.
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Anatómiai Intézet (PTE / ÁOK); Biokémiai és Orvosi Kémiai Intézet (PTE / ÁOK); MTA-PTE Lendület PACAP Kutatócsoport (PTE / KCS); Sebészeti Klinika (PTE / ÁOK); Sebészeti Oktató és Kutató Intézet (PTE / ÁOK)
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<span class="author-name" mtid="10047779"><a href="/gui2/?type=authors&mode=browse&sel=10047779" target="_blank">Varga A (<span class="authorship-author-name">Varga Ádám</span> <span class="authorAux-mtmt"> Sebészet</span>) </a> </span> ; <span class="author-name" mtid="10014558"><a href="/gui2/?type=authors&mode=browse&sel=10014558" target="_blank">Kovacs K (<span class="authorship-author-name">Kovács Krisztina</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Biokémiai és Orvosi Kémiai Intézet</span> ; <span class="author-name" mtid="10021392"><a href="/gui2/?type=authors&mode=browse&sel=10021392" target="_blank">Jancso G (<span class="authorship-author-name">Jancsó Gábor</span> <span class="authorAux-mtmt"> Érsebészet - Vascular surgery</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Oktató és Kutató Intézet</span> ; <span class="author-name" mtid="10016515"><a href="/gui2/?type=authors&mode=browse&sel=10016515" target="_blank">Kiss P (<span class="authorship-author-name">Kiss Péter</span> <span class="authorAux-mtmt"> Neuroanatómia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Anatómiai Intézet</span> ; <span class="author-name" mtid="10013006"><a href="/gui2/?type=authors&mode=browse&sel=10013006" target="_blank">Tamas A (<span class="authorship-author-name">Tamás Andrea</span> <span class="authorAux-mtmt"> Idegtudomány</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Anatómiai Intézet</span> ; <span class="author-name" mtid="10016614"><a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakaly P (<span class="authorship-author-name">Szakály Péter</span> <span class="authorAux-mtmt"> Sebészet</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> ; <span class="author-name" mtid="10039250"><a href="/gui2/?type=authors&mode=browse&sel=10039250" target="_blank">Fulop B (<span class="authorship-author-name">Fülöp Balázs Dániel</span> <span class="authorAux-mtmt"> Orvosi alapkutatások</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Anatómiai Intézet</span> ; <span class="author-name" mtid="10001467"><a href="/gui2/?type=authors&mode=browse&sel=10001467" target="_blank">Reglodi D ✉ (<span class="authorship-author-name">Reglődi Dóra</span> <span class="authorAux-mtmt"> Idegtudományok</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Kutatócsoportok">KCS</span>/MTA-PTE Lendület PACAP Kutatócsoport</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;2940061" target="_blank">Ischemia/reperfusion-induced Kidney Injury in Heterozygous PACAP-deficient Mice.</a></div> <div> <span class="journal-title">TRANSPLANTATION PROCEEDINGS</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0041-1345">0041-1345</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1873-2623">1873-2623</a>)</span>: <span class="journal-volume">47</span> <span class="journal-issue">7</span> <span class="page"> pp 2210-2215 </span> <span class="year">(2015)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Fizetős "> <a style="color:blue" title="10.1016/j.transproceed.2015.07.027" target="_blank" href="https://doi.org/10.1016/j.transproceed.2015.07.027"> DOI </a> </span> <span class="id identifier oa_CLOSED" title=" Zárt "> <a style="color:black" title="83904" target="_blank" href="http://real.mtak.hu/83904"> REAL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000361644000033" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000361644000033"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84940995687" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84940995687"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="26361682" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=26361682&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 19</span> | Független: 5 | Függő: 14 | Nem jelölt: 0 | WoS jelölt: 18 | Scopus jelölt: 18 | WoS/Scopus jelölt: 18 | DOI jelölt: 19 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;2940061&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 10 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 2940061</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 2940061</span> | Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Utolsó módosítás: 2023.02.28. 14:57 Milánkovics Róbert (PTE ÁOK admin 4) </div> <div class="lockedBy">Ideiglenesen zárolva 2023.11.07. 10:01 Pécsi Éva (MTMT Közp 3, admin) </div> </div></div>
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10010110"> <a href="/gui2/?type=authors&mode=browse&sel=10010110" target="_blank">Lázár, G</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10028650"> <a href="/gui2/?type=authors&mode=browse&sel=10028650" target="_blank">Szenohradszky, P</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10028385"> <a href="/gui2/?type=authors&mode=browse&sel=10028385" target="_blank">Szederkényi, E</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Surmann, A </span> <span class="author-type"> </span> ; <span class="author-name" > Toronyi, E </span> <span class="author-type"> </span> ; <span class="author-name" > Török, S </span> <span class="author-type"> </span> ; <span class="author-name" > Földes, K </span> <span class="author-type"> </span> ; <span class="author-name" > Kalmár-Nagy, K </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016614"> <a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakály, P</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;2939027" mtid="2939027" target="_blank">A mikofenolát-nátrium-terápia hatása a vesetranszplantáltak életminőségére</a></div> <div class="pub-info"> <span class="journal-title">LEGE ARTIS MEDICINAE</span> <span class="journal-volume">25</span> : <span class="journal-issue">6-7</span> <span class="page"> pp. 257-264. , 8 p. </span> <span class="year">(2015)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="http://www.elitmed.hu/kiadvanyaink/lam_lege_artis_medicin/a_mikofenolat_natrium_terapia_hatasa_a_vesetranszplantaltak_eletminosegere_13667/" target="_blank" href="http://www.elitmed.hu/kiadvanyaink/lam_lege_artis_medicin/a_mikofenolat_natrium_terapia_hatasa_a_vesetranszplantaltak_eletminosegere_13667/"> Kiadónál </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84939792826" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84939792826"> Scopus </a> </span> <span class="id identifier oa_CLOSED" title=" Zárt "> <a style="color:blue" title="6757" target="_blank" href="http://publicatio.bibl.u-szeged.hu/6757"> SZTE Publicatio </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:2939027 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core">Forrás </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10010110"><a href="/gui2/?type=authors&mode=browse&sel=10010110" target="_blank">Lázár G (<span class="authorship-author-name">Lázár György ifj</span> <span class="authorAux-mtmt"> Klinikai orvostudományok</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> ; <span class="author-name" mtid="10028650"><a href="/gui2/?type=authors&mode=browse&sel=10028650" target="_blank">Szenohradszky P (<span class="authorship-author-name">Szenohradszky Pál</span> <span class="authorAux-mtmt"> sebészet</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> ; <span class="author-name" mtid="10028385"><a href="/gui2/?type=authors&mode=browse&sel=10028385" target="_blank">Szederkényi E (<span class="authorship-author-name">Szederkényi Edit</span> <span class="authorAux-mtmt"> sebészet</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> ; <span class="author-name" >Surmann A </span> ; <span class="author-name" >Toronyi E </span> ; <span class="author-name" >Török S </span> ; <span class="author-name" >Földes K </span> ; <span class="author-name" >Kalmár-Nagy K </span> ; <span class="author-name" mtid="10016614"><a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakály P (<span class="authorship-author-name">Szakály Péter</span> <span class="authorAux-mtmt"> Sebészet</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;2939027" target="_blank">A mikofenolát-nátrium-terápia hatása a vesetranszplantáltak életminőségére</a></div> <div> <span class="journal-title">LEGE ARTIS MEDICINAE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0866-4811">0866-4811</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2063-4161">2063-4161</a>)</span>: <span class="journal-volume">25</span> <span class="journal-issue">6-7</span> <span class="page"> pp 257-264 </span> <span class="year">(2015)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Magyar | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="http://www.elitmed.hu/kiadvanyaink/lam_lege_artis_medicin/a_mikofenolat_natrium_terapia_hatasa_a_vesetranszplantaltak_eletminosegere_13667/" target="_blank" href="http://www.elitmed.hu/kiadvanyaink/lam_lege_artis_medicin/a_mikofenolat_natrium_terapia_hatasa_a_vesetranszplantaltak_eletminosegere_13667/"> Kiadónál </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84939792826" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84939792826"> Scopus </a> </span> <span class="id identifier oa_CLOSED" title=" Zárt "> <a style="color:blue" title="6757" target="_blank" href="http://publicatio.bibl.u-szeged.hu/6757"> SZTE Publicatio </a> </span> </span> <div class="mtid"><span class="long-pub-mtid">Közlemény: 2939027</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 2939027</span> | Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">Scopus</span> </div> <div class="lastModified">Utolsó módosítás: 2023.09.02. 17:01 Milánkovics Róbert (PTE ÁOK admin 4) </div> </div></div>
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10012991"> <a href="/gui2/?type=authors&mode=browse&sel=10012991" target="_blank">Schwarcz, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016614"> <a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakaly, P</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10002667"> <a href="/gui2/?type=authors&mode=browse&sel=10002667" target="_blank">Buki, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10000419"> <a href="/gui2/?type=authors&mode=browse&sel=10000419" target="_blank">Doczi, T</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;2939233" mtid="2939233" target="_blank">Spondylodesist követően kialakult szomszédos szegmentum betegség megoldása minimálisan invazív, anterolateralis feltárásból a lumbális gerincszakaszon: nem szükséges dorsalis műtét?</a></div> <div class="pub-info"> <span class="journal-title">IDEGGYOGYASZATI SZEMLE / CLINICAL NEUROSCIENCE</span> <span class="journal-volume">68</span> : <span class="journal-issue">7-8</span> <span class="page"> pp. 273-277. , 5 p. </span> <span class="year">(2015)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Fizetős "> <a style="color:blue" title="10.18071/isz.68.0273" target="_blank" href="https://doi.org/10.18071/isz.68.0273"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000358897100007" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000358897100007"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84941571028" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84941571028"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="26380422" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=26380422&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:2939233 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core">Forrás </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10012991"><a href="/gui2/?type=authors&mode=browse&sel=10012991" target="_blank">Schwarcz A (<span class="authorship-author-name">Schwarcz Attila</span> <span class="authorAux-mtmt"> Mágneses rezonanciás képalkotás</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Idegsebészeti Klinika</span> ; <span class="author-name" mtid="10016614"><a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakaly P (<span class="authorship-author-name">Szakály Péter</span> <span class="authorAux-mtmt"> Sebészet</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> ; <span class="author-name" mtid="10002667"><a href="/gui2/?type=authors&mode=browse&sel=10002667" target="_blank">Buki A (<span class="authorship-author-name">Büki András</span> <span class="authorAux-mtmt"> Idegsebészet, idegtudományok</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Idegsebészeti Klinika</span> ; <span class="author-name" mtid="10000419"><a href="/gui2/?type=authors&mode=browse&sel=10000419" target="_blank">Doczi T (<span class="authorship-author-name">Dóczi Tamás Péter</span> <span class="authorAux-mtmt"> Idegsebészet</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Idegsebészeti Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;2939233" target="_blank">Spondylodesist követően kialakult szomszédos szegmentum betegség megoldása minimálisan invazív, anterolateralis feltárásból a lumbális gerincszakaszon: nem szükséges dorsalis műtét?</a></div> <div> <span class="journal-title">IDEGGYOGYASZATI SZEMLE / CLINICAL NEUROSCIENCE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0019-1442">0019-1442</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2498-6208">2498-6208</a>)</span>: <span class="journal-volume">68</span> <span class="journal-issue">7-8</span> <span class="page"> pp 273-277 </span> <span class="year">(2015)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Magyar | </span> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Fizetős "> <a style="color:blue" title="10.18071/isz.68.0273" target="_blank" href="https://doi.org/10.18071/isz.68.0273"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000358897100007" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000358897100007"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84941571028" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84941571028"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="26380422" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=26380422&dopt=Abstract"> PubMed </a> </span> </span> <div class="mtid"><span class="long-pub-mtid">Közlemény: 2939233</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 2939233</span> | Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS</span> </div> <div class="lastModified">Utolsó módosítás: 2023.09.02. 17:01 Milánkovics Róbert (PTE ÁOK admin 4) </div> </div></div>
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Acetylsalicylic Acid Resistance After Renal Transplantation.
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Background: Cardiovascular diseases are a leading cause of mortality after kidney transplantation. According to guidelines, acetylsalicylic acid (ASA) must be given as preventive antiplatelet therapy, but resistance to this drug is also well-known. Patients and Methods: A total of 214 renal transplant patients were included in our study and took 100 mg of ASA q.d. Aggregometry was performed to determine resistance. Twenty-four variables were examined using logistic regression analysis as possible causes of resistance. Results: ASA resistance was observed in 40.18% of the patients. Resistance reduced concomitant statin therapy and significantly increased simultaneous cyclosporine therapy. Conclusion: Our study assessed the post-transplant ASA resistance in a large population. Clarification of this matter is crutial, since one of the major preventive pharmacological therapies of cardiovascular mortality is not effective in a significant number of patients.
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I.sz. Belgyógyászati Klinika (PTE / ÁOK); Orvosi Népegészségtani Intézet (PTE / ÁOK); Sebészeti Klinika (PTE / ÁOK)
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10047779"> <a href="/gui2/?type=authors&mode=browse&sel=10047779" target="_blank">Varga, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10025798"> <a href="/gui2/?type=authors&mode=browse&sel=10025798" target="_blank">Sandor, B</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Nagy, KK </span> <span class="author-type"> </span> ; <span class="author-name" > Viola, M </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10029477"> <a href="/gui2/?type=authors&mode=browse&sel=10029477" target="_blank">Toth, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016527"> <a href="/gui2/?type=authors&mode=browse&sel=10016527" target="_blank">Gombos, K</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10004892"> <a href="/gui2/?type=authors&mode=browse&sel=10004892" target="_blank">Toth, K</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016614"> <a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakaly, P</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;2828833" mtid="2828833" target="_blank">Acetylsalicylic Acid Resistance After Renal Transplantation.</a></div> <div class="pub-info"> <span class="journal-title">IN VIVO</span> <span class="journal-volume">29</span> : <span class="journal-issue">1</span> <span class="page"> pp. 141-144. , 4 p. </span> <span class="year">(2015)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Fizetős "> <a style="color:black" title="http://iv.iiarjournals.org/content/29/1/141.abstract" target="_blank" href="http://iv.iiarjournals.org/content/29/1/141.abstract"> Kiadónál </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000348134300023" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000348134300023"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84921635644" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84921635644"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="25600544" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=25600544&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:2828833 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core">Forrás </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 1 | Függő: 0 | Nem jelölt: 0 | Scopus jelölt: 1 | WoS/Scopus jelölt: 1 | DOI jelölt: 1 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10047779"><a href="/gui2/?type=authors&mode=browse&sel=10047779" target="_blank">Varga A (<span class="authorship-author-name">Varga Ádám</span> <span class="authorAux-mtmt"> Sebészet</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> ; <span class="author-name" mtid="10025798"><a href="/gui2/?type=authors&mode=browse&sel=10025798" target="_blank">Sandor B (<span class="authorship-author-name">Sándor Barbara</span> <span class="authorAux-mtmt"> Kardiológia, kardiológiai rehabilitáció</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/I.sz. Belgyógyászati Klinika</span> ; <span class="author-name" >Nagy KK </span> ; <span class="author-name" >Viola M </span> ; <span class="author-name" mtid="10029477"><a href="/gui2/?type=authors&mode=browse&sel=10029477" target="_blank">Toth A (<span class="authorship-author-name">Tóth András</span> <span class="authorAux-mtmt"> Haemorheologia-radiológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/I.sz. Belgyógyászati Klinika</span> ; <span class="author-name" mtid="10016527"><a href="/gui2/?type=authors&mode=browse&sel=10016527" target="_blank">Gombos K (<span class="authorship-author-name">Gombos Katalin</span> <span class="authorAux-mtmt"> Laboratóriumi medicina</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Orvosi Népegészségtani Intézet</span> ; <span class="author-name" mtid="10004892"><a href="/gui2/?type=authors&mode=browse&sel=10004892" target="_blank">Toth K (<span class="authorship-author-name">Tóth Kálmán</span> <span class="authorAux-mtmt"> Cardiologia-haemorheologia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/I.sz. Belgyógyászati Klinika</span> ; <span class="author-name" mtid="10016614"><a href="/gui2/?type=authors&mode=browse&sel=10016614" target="_blank">Szakaly P (<span class="authorship-author-name">Szakály Péter</span> <span class="authorAux-mtmt"> Sebészet</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Sebészeti Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;2828833" target="_blank">Acetylsalicylic Acid Resistance After Renal Transplantation.</a></div> <div> <span class="journal-title">IN VIVO</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0258-851X">0258-851X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1791-7549">1791-7549</a>)</span>: <span class="journal-volume">29</span> <span class="journal-issue">1</span> <span class="page"> pp 141-144 </span> <span class="year">(2015)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Fizetős "> <a style="color:black" title="http://iv.iiarjournals.org/content/29/1/141.abstract" target="_blank" href="http://iv.iiarjournals.org/content/29/1/141.abstract"> Kiadónál </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000348134300023" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000348134300023"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84921635644" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84921635644"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="25600544" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=25600544&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 1 | Függő: 0 | Nem jelölt: 0 | Scopus jelölt: 1 | WoS/Scopus jelölt: 1 | DOI jelölt: 1 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 2828833</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 2828833</span> | Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Utolsó módosítás: 2023.09.02. 16:56 Milánkovics Róbert (PTE ÁOK admin 4) </div> </div></div>