@article{MTMT:3241815,
	title = {Nyíltláncú és makrociklusos aminokarboxilát ligandumok szintézise és fémkomplexeik vizsgálata. koordinációs kémia az orvosi képalkotás szolgálatában},
	url = {https://m2.mtmt.hu/api/publication/3241815},
	author = {Tircsó, Gyula and Brücher, Ernő and Baranyai, Zsolt and Kálmán, Ferenc Krisztián and Tóth, Imre},
	doi = {10.24100/MKF.2017.02.82},
	journal-iso = {MAGY KÉM FOLY KÉM KÖZL},
	journal = {MAGYAR KÉMIAI FOLYÓIRAT - KÉMIAI KÖZLEMÉNYEK (1997-)},
	volume = {123},
	unique-id = {3241815},
	issn = {1418-9933},
	year = {2017},
	eissn = {1418-8600},
	pages = {82-93},
	orcid-numbers = {Tircsó, Gyula/0000-0002-7896-7890; Baranyai, Zsolt/0000-0001-6844-7974; Tóth, Imre/0000-0001-6718-9977}
}

@article{MTMT:1378688,
	title = {O-17 NMR-STUDY OF WATER EXCHANGE ON [GD(DTPA)(H2O)]2- AND [GD(DOTA)(H2O)]- RELATED TO NMR IMAGING},
	url = {https://m2.mtmt.hu/api/publication/1378688},
	author = {Micskei, Károly Endre and HELM, L and Brücher, Ernő and MERBACH, AE},
	doi = {10.1021/ic00070a013},
	journal-iso = {INORG CHEM},
	journal = {INORGANIC CHEMISTRY},
	volume = {32},
	unique-id = {1378688},
	issn = {0020-1669},
	abstract = {The water-exchange rate constants for the [Gd(DTPA)(H2O)]2- and [Gd(DOTA)(H2O)]-complexes as determined by variable-temperature O-17 NMR are respectively k(ex)298 = (4.1 +/- 0.3) X 10(6) and (4.8 +/- 0.4) X 10(6) s-1. The activation volumes (DELTAV(double dagger)), measured up to 200 MPa, are 12.5 +/- 0.2 and 10.5 +/- 0.2 cm3 mol-1, indicating an extreme dissociative activation mode for the water-exchange mechanism. The mechanism (D) is further supported by the large activation enthalpies (DELTAH(double dagger) = +52.0 +/- 1.4 and +48.8 +/- 1.6 kJ mol-1) and positive entropies (DELTAS(double dagger) = +56.2 +/- 5 and +46.6 +/- 6 kJ mol-1 K-1) obtained for the [Gd(DTPA)(H2O)]2- and [Gd(DOTA)(H2O)]- complexes, respectively. In the first coordination sphere of these two monoaqua complexes there is only space for one water molecule, and thus the bond breaking of the coordinated water should be the rate-determining step. The O-17 relaxation contribution of the second coordination sphere was estimated by investigating [Gd(TETA)]-, which has no water in the first coordination sphere. All these considerations lead to the conclusion that the effectiveness of [Gd(DTPA)(H2O)]2- and [Gd(DOTA)(H2O)]- as contrast agents in MRI is not limited by the relatively low water-exchange rates but by T1m, the longitudinal relaxation time of water protons in the first coordination sphere.},
	keywords = {MECHANISMS; LUMINESCENCE; KINETICS; DYNAMICS; IONS; DOTA; LANTHANIDE(III) COMPLEXES; DIETHYLENETRIAMINEPENTAACETATE},
	year = {1993},
	eissn = {1520-510X},
	pages = {3844-3850}
}