TY - JOUR AU - Pasinato, Anna AU - Singh, Garima TI - Lichens are a treasure chest of bioactive compounds: fact or fake? JF - NEW PHYTOLOGIST J2 - NEW PHYTOL PY - 2025 PG - 7 SN - 0028-646X DO - 10.1111/nph.70034 UR - https://m2.mtmt.hu/api/publication/35981463 ID - 35981463 N1 - Department of Biology, University of Padova, Via U. Bassi, 58/B, Padova, 35121, Italy National Biodiversity Future Center (NBFC), Piazza Marina, 61, Palermo, 90133, Italy Botanical Garden, University of Padova, Via Orto Botanico, 15, Padova, 35123, Italy Export Date: 18 March 2025; Cited By: 0; Correspondence Address: G. Singh; Department of Biology, University of Padova, Padova, Via U. Bassi, 58/B, 35121, Italy; email: garima.singh@unipd.it; CODEN: NEPHA LA - English DB - MTMT ER - TY - JOUR AU - Muhoro, Arthur AU - Kosgei, J. J. AU - Njangiru, I. K. AU - Rasaki, L. A. AU - Farkas, Edit TI - Potential of Cladonia Foliacea Extract as an Oral Toxic Insecticide Against Adult Anopheles Gambiae, Malaria Vector in Western Kenya JF - ACTA BOTANICA HUNGARICA J2 - ACTA BOT HUNG VL - 66 PY - 2024 IS - 3-4 SP - 233 EP - 250 PG - 18 SN - 0236-6495 DO - 10.1556/034.66.2024.3-4.7 UR - https://m2.mtmt.hu/api/publication/35628128 ID - 35628128 N1 - Export Date: 11 February 2025 Correspondence Address: Muhoro, A.M.; School of Biological Sciences, Páter K. u. 1, Hungary; email: arthmacharia@yahoo.com AB - Plasmodium falciparum is primarily transmitted by Anopheles gambiae . Malaria caused by Plasmodium falciparum is a major public health issue in western Kenya and sub-Saharan Africa, accounting for 90% of malaria deaths. The primary methods of malaria prevention are indoor residual spraying and the use of insecticide-treated nets. These tools face challenges such as mosquito resistance to insecticides as well as their toxic effect to the non-target organism, therefore this study aims to explore the application of lichen secondary metabolites as potential oral biological insecticides by assessing mosquito mortality in varying concentrations. Lichen secondary metabolites were extracted from Cladonia foliacea thalli. Bioassay experiments were conducted on A. gambiae Kisumu strain mosquitoes. Mortality rates were measured after ingesting sugar bait and lichen extracts in different concentrations. Three test replicates and negative control were used, with mortality measured after 4, 24, 48, and 72 hours. Analysis using three-way analysis of variance with twoway interactions was performed using R program to determine the effect of different lichen extract concentrations, time of exposures and mosquito sex on mortality. Our results showed that the ingestion of C. foliacea extract at 50 mg/ml and a post-exposure period of 24 to 48 hours had a maximum effect on the mortality rate of targeted male and female A. gambiae . No statistical difference was found between male and female mosquitoes in mortality. Our study confirms firstly that the extract of C. foliacea is a promising oral toxic agent against adult malaria vector A. gambiae . LA - English DB - MTMT ER - TY - JOUR AU - Muhoro, Arthur AU - Ochomo, Eric Odhiambo AU - Njangiru, Isaac Kinyua AU - Kosgei, Jackline Jeruto AU - Rasaki, Laide Abbas AU - Farkas, Edit TI - A study on the effectiveness of (+)-usnic acid as oral toxic sugar bait against adult male and female Anopheles gambiae JF - MALARIA JOURNAL J2 - MALARIA J VL - 23 PY - 2024 IS - 1 PG - 8 SN - 1475-2875 DO - 10.1186/s12936-024-05141-4 UR - https://m2.mtmt.hu/api/publication/35466494 ID - 35466494 N1 - Doctoral School of Biological Sciences, Hungarian University of Agriculture and Life Sciences, Páter K. U. 1, Gödöllő, 2100, Hungary Kenya Medical Research Institute-Centre for Global Health Research (KEMRI-CGHR), P.O. Box 1578, Kisumu, 40100, Kenya Institute of Pharmacodynamics and Biopharmacy, University of Szeged, Eötvös U. 6, Szeged, 6720, Hungary Department of Crop Sciences, North Carolina State University, Raleigh, NC 27695, United States HUN-REN Centre for Ecological Research, Institute of Ecology and Botany, Alkotmány u. 2–4, Vácrátót, 2163, Hungary Export Date: 11 February 2025 Correspondence Address: Muhoro, A.M.; Doctoral School of Biological Sciences, Páter K. U. 1, Hungary; email: arthmacharia@yahoo.com LA - English DB - MTMT ER -