TY - JOUR AU - Ichita, C. AU - Kishino, T. AU - Aoki, T. AU - Machida, T. AU - Murakami, T. AU - Sato, Y. AU - Nagata, N. TI - Updated evidence on epidemiology, diagnosis, and treatment for colonic diverticular bleeding JF - DEN OPEN J2 - DEN OPEN VL - 6 PY - 2026 IS - 1 SN - 2692-4609 DO - 10.1002/deo2.70122 UR - https://m2.mtmt.hu/api/publication/36183141 ID - 36183141 N1 - Gastroenterology Medicine Center, Shonan Kamakura General Hospital, Kanagawa, Japan Department of Health Data Science, Yokohama City University, Kanagawa, Japan Department of Gastroenterology and Hepatology, Center for Digestive and Liver Diseases, Nara City Hospital, Nara, Japan Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan Department of Surgery, Saiseikai Hyogo Prefectural Hospital, Hyogo, Japan Department of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan Division of Gastroenterology, St Marianna University School of Medicine, Kanagawa, Japan Department of Gastroenterological Endoscopy, Tokyo Medical University, Tokyo, Japan Export Date: 08 June 2025; Cited By: 0; Correspondence Address: C. Ichita; Gastroenterology Medicine Center, Shonan Kamakura General Hospital, Kamakura, 1370–1, OkamotoKanagawa, 247–8533, Japan; email: ichikamasa@yahoo.co.jp LA - English DB - MTMT ER - TY - JOUR AU - Mertens, Alexander AU - Essing, Tobias AU - Kunstein, Anselm AU - Weigel, Christian AU - Bode, Johannes AU - Roderburg, Christoph AU - Luedde, Tom AU - Kandler, Jennis AU - Loosen, Sven H. TI - Acute Variceal Hemorrhage in Germany-A Nationwide Study of 65,357 Hospitalized Cases JF - CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY J2 - CAN J GASTROENTEROL VL - 2024 PY - 2024 PG - 15 SN - 2291-2789 DO - 10.1155/2024/5453294 UR - https://m2.mtmt.hu/api/publication/35637050 ID - 35637050 N1 - Funding Agency and Grant Number: European Research Council Funding text: The authors would like to thank Janina Loske of the Federal Statistical Office for her professional support in remote data analysis. They acknowledge using Grammarly (features: clarity and correctness) at the final manuscript preparation stage. Figures use icons by thenounproject.com. AB - Background: Acute variceal hemorrhage (AVH) is a frequent cause of upper gastrointestinal bleeding (UGIB) in liver cirrhosis. Most cases require urgent endoscopic intervention due to potentially life-threatening courses. Different endoscopic hemostasis techniques can be used, in particular endoscopic variceal ligation (EVL) and endoscopic sclerotherapy (EST), depending on the bleeding side (esophageal, fundal, and gastric) as well as radiological interventions (e.g., embolization and transjugular intrahepatic portosystemic shunt [TIPS]). This study aimed to investigate trends in incidence, treatment modalities, and outcome parameters, such as in-hospital mortality and adverse events in Germany.Methods: We evaluated the current epidemiological trends, therapeutic strategies, and in-hospital mortality of AVH in Germany based on the standardized hospital discharge data provided by the German Federal Statistical Office from 2010 to 2019.Results: A total of 65,357 AVH cases, predominately males (68.3%), were included in the analysis. The annual incidence rate (hospitalization cases per 100,000 persons) was 8.9. The in-hospital mortality was 18.6%. The most common underlying disease was alcohol-related liver cirrhosis (60.6%). The most common clinical complication was bleeding anemia (60.1%), whereas hypovolemic shock (12.8%) was the less frequent. In esophageal variceal hemorrhage (EVH), EVL was the most frequently performed endoscopic therapy, while in gastric variceal hemorrhage (GVH), EST and fibrin glue injection were the most commonly performed therapies. EVL showed the lowest in-hospital mortality (12.3%) in EVH, while EST showed favorable results (14% in-hospital mortality) in GVH. Combination therapies overall showed a higher in-hospital mortality and were more frequent in GVH. The presence of hypovolemic shock, AKI, sepsis, artificial ventilation, ARDS, bleeding anemia, hepatic encephalopathy, and male sex was associated with a significantly worse outcome.Conclusion: Our study provides detailed insight into the incidence, patient-related risk factors, endoscopic treatment, and in-hospital mortality in a sizeable AVH collective in Germany. These data might help improve risk stratification and treatment strategies for AVH patients in the future. LA - English DB - MTMT ER - TY - JOUR AU - Windschill, Daniel AU - Kerr, Caleb AU - Disterhaft, Patrick AU - Singh, Avtar TI - A PRESSING ISSUE: PATHOPHYSIOLOGIC CONSEQUENCES OF ANATOMIC VARIATION IN THE PRESENCE OF COMBINED SHOCK JF - CHEST J2 - CHEST VL - 166 PY - 2024 IS - 4 SP - 2149A EP - 2150A PG - 2 SN - 0012-3692 UR - https://m2.mtmt.hu/api/publication/35708716 ID - 35708716 N1 - Supplement: S LA - English DB - MTMT ER - TY - JOUR AU - Jaxymbaev, N. AU - Baysekeev, T. AU - Choi, E.D. AU - Kochorov, O. AU - Mukanbaev, K. AU - Turkmenov, A. TI - Endoscopic Hemostasis in Ulcerative Gastroduodenal Bleeding JF - INTERNATIONAL JOURNAL OF CHEMICAL AND BIOCHEMICAL SCIENCES VL - 24 PY - 2023 IS - 6 SP - 470 EP - 478 PG - 9 SN - 2226-9614 UR - https://m2.mtmt.hu/api/publication/34751287 ID - 34751287 N1 - Kyrgyz State Medical Institute of Post-Graduate Training and Continuous Education named S. B. Daniyarov, 144a Bokonbaeva str., Bishkek, 720017, Kyrgyzstan Akhunbaev Kyrgyz State Medical Academy, 92 Akhunbaev str., Bishkek, 720020, Kyrgyzstan Royal Metropolitan University, 172 Moskoskaya str., Bishkek, 720010, Kyrgyzstan Kyrgyz-Russian Slavic University named after B. N. Yeltsin, 44 Kiyevskaya str., Bishkek, 720000, Kyrgyzstan National Center for Phthisiology, 90a Isa Akhunbaev str., Bishkek, 720075, Kyrgyzstan Export Date: 21 March 2024 Correspondence Address: Jaxymbaev, N.; Kyrgyz State Medical Institute of Post-Graduate Training and Continuous Education named S. B. Daniyarov, 144a Bokonbaeva str., Kyrgyzstan; email: ndzhaksymbayev@bk.ru LA - English DB - MTMT ER -