TY  - JOUR
AU  - Fragkiadaki, Persefoni
AU  - Kouvidi, Elisavet
AU  - Angelaki, Anna
AU  - Nikolopoulou, Dimitra
AU  - Vakonaki, Elena
AU  - Tsatsakis, Aristidis
TI  - Evaluation of telomere length and telomerase activity on predicting in vitro fertilization treatment outcomes
JF  - JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
J2  - J ASSIST REPROD GEN
PY  - 2024
PG  - 11
SN  - 1058-0468
DO  - 10.1007/s10815-024-03117-6
UR  - https://m2.mtmt.hu/api/publication/35019374
ID  - 35019374
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Pańczyszyn, A.
AU  - Boniewska-Bernacka, E.
AU  - Wertel, I.
AU  - Sadakierska-Chudy, A.
AU  - Goc, A.
TI  - Telomeres and SIRT1 as Biomarkers of Gamete Oxidative Stress, Fertility, and Potential IVF Outcome
JF  - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
J2  - INT J MOL SCI
VL  - 25
PY  - 2024
IS  - 16
SN  - 1661-6596
DO  - 10.3390/ijms25168652
UR  - https://m2.mtmt.hu/api/publication/35205302
ID  - 35205302
N1  - Institute of Medical Sciences, Department of Biology and Genetics, Faculty of Medicine, University of Opole, Oleska 48, Opole, 45-052, Poland            
            Independent Laboratory of Cancer Diagnostics and Immunology, Medical University of Lublin, Chodźki 1, Lublin, 20-093, Poland            
            Department of Genetics, Faculty of Medicine and Health Sciences, Collegium Medicum, Andrzej Frycz Modrzewski Krakow University, Gustawa Herlinga-Grudzinskiego 1, Krakow, 30-705, Poland            
            Export Date: 5 September 2024            
            Correspondence Address: Pańczyszyn, A.; Institute of Medical Sciences, Oleska 48, Poland; email: apanczyszyn@uni.opole.pl
AB  - The number of infertile couples undergoing in vitro fertilisation (IVF) has increased significantly. The efficacy of this procedure is contingent upon a multitude of factors, including gamete quality. One factor influencing gamete quality is oxidative stress, which leads to telomere damage and accelerates cellular ageing. Identifying new biomarkers that can predict the success of assisted reproduction techniques is a current relevant area of research. In this review, we discuss the potential role of SIRT1, a protein known to protect against oxidative stress and telomeres, which are responsible for genome stability, as biomarkers of gamete quality and assisted reproduction technique outcomes. © 2024 by the authors.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Chen, Yu
AU  - Yang, Jiahao
AU  - Zhang, Ling
TI  - The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy
JF  - ANTIOXIDANTS
J2  - ANTIOXIDANTS-BASEL
VL  - 12
PY  - 2023
IS  - 12
PG  - 16
SN  - 2076-3921
DO  - 10.3390/antiox12122117
UR  - https://m2.mtmt.hu/api/publication/34567763
ID  - 34567763
N1  - Funding Agency and Grant Number: Wuhan National High Magnetic Field Center
            Funding text: No Statement Available
AB  - Oocyte quality is a pivotal determinant of assisted reproductive outcomes. The quality of oocytes is intricately linked to their developmental microenvironment, particularly the levels of oxidative stress within the follicular fluid. Oxidative stress levels in follicular fluid may have a substantial influence on oocyte health, thereby impacting the outcomes of ART procedures. This review meticulously explores the intricate relationship between oxidative stress in follicular fluid and ART outcomes. Furthermore, it delves into strategies aimed at ameliorating the oxidative stress status of follicular fluid, with the overarching goal of enhancing the overall efficacy of ART. This research endeavors to establish a robust foundation and provide valuable guidance for clinical treatment approaches, particularly in the context of infertile women, including those of advanced maternal age.
LA  - English
DB  - MTMT
ER  -