TY - JOUR AU - Fezzi, Simone AU - Ding, Daixin AU - Mahfoud, Felix AU - Huang, Jiayue AU - Lansky, Alexandra J. AU - Tu, Shengxian AU - Wijns, William TI - Illusion of revascularization: does anyone achieve optimal revascularization during percutaneous coronary intervention? JF - NATURE REVIEWS CARDIOLOGY J2 - NAT REV CARDIOL PY - 2024 PG - 11 SN - 1759-5002 DO - 10.1038/s41569-024-01014-0 UR - https://m2.mtmt.hu/api/publication/34920985 ID - 34920985 N1 - The Lambe Institute for Translational Medicine, the Smart Sensors Laboratory and Curam, University of Galway, Galway, Ireland Division of Cardiology, Department of Medicine, University of Verona, Verona, Italy Department of Cardiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China Saarland University Hospital, Internal Medicine III, Cardiology, Angiology, Intensive Care Medicine, Homburg/Saar, Germany Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, United States University Heart Center Basel, Department of Cardiology, University Basel, Basel, Switzerland Biomedical Instrument Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, United States Department of Cardiology, Ren Ji Hospital, School of Medicine, and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China Export Date: 4 July 2024 Correspondence Address: Wijns, W.; The Lambe Institute for Translational Medicine, Ireland; email: william.wyns@universityofgalway.ie Correspondence Address: Tu, S.; Department of Cardiology, China; email: sxtu@sjtu.edu.cn LA - English DB - MTMT ER - TY - JOUR AU - Improta, R. AU - Di, Pietro G. AU - Giansanti, M. AU - Bruno, F. AU - De, Filippo O. AU - Tocci, M. AU - Colantonio, R. AU - Sardella, G. AU - D’Ascenzo, F. AU - Mancone, M. TI - Comparison between Imaging and Physiology in Guiding Coronary Revascularization: A Meta-Analysis JF - JOURNAL OF CLINICAL MEDICINE J2 - J CLIN MED VL - 13 PY - 2024 IS - 9 SN - 2077-0383 DO - 10.3390/jcm13092504 UR - https://m2.mtmt.hu/api/publication/34968946 ID - 34968946 N1 - Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Umberto I Hospital, Sapienza University of Rome, Viale del Policlinico 155 (Emodinamica A, Ottavo Padiglione, II Piano), Rome, 00161, Italy Department of Medical Science, Division of Cardiology, Molinette Hospital, Turin University, Turin, 10124, Italy Export Date: 10 June 2024 Correspondence Address: Mancone, M.; Department of Clinical, Viale del Policlinico 155 (Emodinamica A, Ottavo Padiglione, II Piano), Italy; email: massimo.mancone@uniroma1.it AB - Background: Percutaneous coronary intervention (PCI) is a widely used revascularization strategy for coronary artery disease. The choice between imaging-guided and physiology-guided PCI has been a subject of debate. This meta-analysis aims to systematically compare outcomes between imaging and physiology-guided PCI and management of intermediate coronary lesions (ICLs). Methods: A comprehensive literature search was conducted across major databases for studies published up to December 2023 following PRISMA guidelines. Seven eligible studies comparing imaging-guided and physiology-guided PCI were selected for the final analysis. Relevant outcome measures included major adverse cardiovascular events (MACE), target vessel revascularization (TVR), target vessel failure (TVF), and target lesion revascularization (TLR). Subgroup analysis was performed for ICLs. Results: A total of 5701 patients were included in the meta-analysis. After a mean follow-up of 2.1 years, imaging-guided PCI was associated with lower rates of TVR compared to physiology-guided PCI (OR 0.70, 95% CI 0.52–0.95, p = 0.02); concerning MACE, TVF, and TLR, no differences were found. When the analysis was restricted to studies considering ICLs management, there were no differences between the two techniques. Meta regression analysis did not show any impact of acute coronary syndromes (ACS) presentation on MACE and TVR. Conclusions: The findings suggest that imaging-guided PCI may reduce the need for future revascularization of the target vessel compared to the functional-guided approach, and this result was not influenced by ACS presentation. These results may have important implications for clinical practice, guiding interventional cardiologists in selecting the most appropriate guidance strategy. © 2024 by the authors. LA - English DB - MTMT ER - TY - JOUR AU - Ramunddal, Truls AU - Dworeck, Christian AU - Torild, Petronella AU - Andreen, Sofie AU - Gan, Li-Ming AU - Hirlekar, Geir AU - Ioanes, Dan AU - Myredal, Anna AU - Odenstedt, Jacob AU - Petursson, Petur AU - Pylova, Tetiana AU - Topel, Fanny AU - Volz, Sebastian AU - Hilmersson, Mats AU - Redfors, Bjorn AU - Angeras, Oskar TI - Safety and Feasibility Using a Fluid-Filled Wire to Avoid Hydrostatic Errors in Physiological Intracoronary Measurements JF - CARDIOLOGY RESEARCH AND PRACTICE J2 - CARDIOL RES PRAC VL - 2024 PY - 2024 PG - 9 SN - 2090-0597 DO - 10.1155/2024/6664482 UR - https://m2.mtmt.hu/api/publication/34667397 ID - 34667397 LA - English DB - MTMT ER - TY - JOUR AU - Tsai, T.-Y. AU - Aldujeli, A. AU - Haq, A. AU - Knokneris, A. AU - Briedis, K. AU - Hughes, D. AU - Unikas, R. AU - Renkens, M. AU - Revaiah, P.C. AU - Tobe, A. AU - Miyashita, K. AU - Sharif, F. AU - Garg, S. AU - Onuma, Y. AU - Serruys, P.W. TI - The Impact of Microvascular Resistance Reserve on the Outcome of Patients With STEMI JF - JACC-CARDIOVASCULAR INTERVENTIONS J2 - JACC-CARDIOVASC INTERV VL - 17 PY - 2024 IS - 10 SP - 1214 EP - 1227 PG - 14 SN - 1936-8798 DO - 10.1016/j.jcin.2024.03.024 UR - https://m2.mtmt.hu/api/publication/34969305 ID - 34969305 N1 - CORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, Galway, Ireland Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan Lithuanian University of Health Sciences, Kaunas, Lithuania Abbott Northwestern Hospital/Minneapolis Heart Institute Foundation, Minneapolis, MN, United States Klaipeda University Hospital, Klaipeda, Lithuania Sligo University Hospital, Sligo, Ireland Department of Cardiology, University Hospital Galway, University of Galway, Galway, Ireland Department of Cardiology, Royal Blackburn Hospital, Blackburn, United Kingdom Cited By :1 Export Date: 10 June 2024 Correspondence Address: Serruys, P.W.; CORRIB Research Centre for Advanced Imaging and Core Lab, University Road, Ireland; email: patrick.serruys@universityofgalway.ie Chemicals/CAS: adenosine, 58-61-7; glyceryl trinitrate, 55-63-0, 80738-44-9 AB - Background: Microvascular resistance reserve (MRR) can characterize coronary microvascular dysfunction (CMD); however, its prognostic impact in ST-segment elevation myocardial infarction (STEMI) patients remains undefined. Objectives: This study sought to investigate the prevalence of CMD in STEMI patients and to elucidate the prognostic performance of MRR. Methods: This prospective cohort study enrolled 210 STEMI patients with multivessel disease who underwent successful revascularization and returned at 3 months for coronary physiology assessments with bolus thermodilution. The prevalence of CMD (MRR <3) and the association between MRR and major adverse cardiovascular and cerebrovascular events (MACCEs) at 12 months were investigated. Results: The median age of patients was 65 years, and 59.5% were men. At the 3-month follow-up, 56 patients (27%) had CMD (MRR <3.0). The number of MACCEs at 12 months was higher in patients with vs without CMD (48.2% vs 11.0%; P < 0.001). MRR was independently associated with 12-month MACCEs (HR: 0.45 per unit increase; 95% CI: 0.31-0.67; P < 0.001) and with stroke, heart failure, and poorer recovery in left ventricular systolic function. The areas under the receiver-operating characteristic curves for predicting MACCEs at 12 months with fractional flow reserve, coronary flow reserve (CFR), the index of microvascular resistance (IMR), and MRR were 0.609, 0.762, 0.781, and 0.743, respectively. The prognostic performance of CFR, IMR, and MRR were all comparable. Conclusions: The novel parameter MRR is a prognostic marker of MACCEs in STEMI patients with a comparable performance to CFR and IMR. (Impact of TMAO Serum Levels on Hyperemic IMR in STEMI Patients [TAMIR]; NCT05406297) © 2024 American College of Cardiology Foundation LA - English DB - MTMT ER - TY - JOUR AU - Caullery, Benoit AU - Riou, Laurent AU - Barone-Rochette, Gilles TI - Coronary Angiography Upgraded by Imaging Post-Processing: Present and Future Directions JF - DIAGNOSTICS J2 - DIAGNOSTICS VL - 13 PY - 2023 IS - 11 PG - 18 SN - 2075-4418 DO - 10.3390/diagnostics13111978 UR - https://m2.mtmt.hu/api/publication/34281640 ID - 34281640 AB - Advances in computer technology and image processing now allow us to obtain from angiographic images a large variety of information on coronary physiology without the use of a guide-wire as a diagnostic information equivalent to FFR and iFR but also information allowing for the performance of a real virtual percutaneous coronary intervention (PCI) and finally the ability to obtain information to optimize the results of PCI. With specific software, it is now possible to have a real upgrading of invasive coronary angiography. In this review, we present the different advances in this field and discuss the future perspectives offered by this technology. LA - English DB - MTMT ER - TY - JOUR AU - Cortese, Bernardo AU - Malakouti, Sara AU - Mazhar, Waqas AU - Lazar, Florin Leontin AU - Munjal, Amit AU - Mougang, Yolande Ketchanji TI - Long-term benefits of drug-coated balloons for revascularization JF - MINERVA CARDIOLOGY AND ANGIOLOGY J2 - MINERVA CARDIOL ANGIOL VL - In press PY - 2023 PG - 12 SN - 2724-5683 DO - 10.23736/S2724-5683.23.06425-6 UR - https://m2.mtmt.hu/api/publication/34604663 ID - 34604663 AB - ABS TRACT Percutaneous coronary intervention (PCI) with drug-eluting stents (DES) represents the treatment of choice for the ma-jority of patients with coronary artery disease. While currently available DES, in addition to physiological support, has failed to show the non-inferiority to coronary artery bypass grafting (CABG) in terms of cumulative incidence of clinical events over the short-term follow-up. Studies have also shown that DES is associated with an increased risk of target vessel revascularization compared to CABG after long-term follow-up. Drug-coated balloons (DCB) have been shown to provide clinically significant benefits in the management of in-stent restenosis and diffuse coronary artery disease, as well as small coronary artery lesions. The aim of this review was to describe the inherent technical limitations of DES and highlight the potential advantages of PCI with DCB for long-term outcomes and potentially demonstrate its non-inferiority to CABG. Currently, ongoing studies will provide more information and help to understand if a blended therapy of DCB+DES can match the performance of CABG in the need for revascularization in more complex patients. LA - English DB - MTMT ER - TY - JOUR AU - Koo, B.-K. AU - Lee, J.M. AU - Hwang, D. AU - Park, S. AU - Shiono, Y. AU - Yonetsu, T. AU - Lee, S.H. AU - Kawase, Y. AU - Ahn, J.-M. AU - Matsuo, H. AU - Shin, E.-S. AU - Hu, X. AU - Ding, D. AU - Fezzi, S. AU - Tu, S. AU - Low, A.F. AU - Kubo, T. AU - Nam, C.-W. AU - Yong, A.S.C. AU - Harding, S.A. AU - Xu, B. AU - Hur, S.-H. AU - Choo, G.H. AU - Tan, H.C. AU - Mullasari, A. AU - Hsieh, I.-C. AU - Kakuta, T. AU - Akasaka, T. AU - Wang, J. AU - Tahk, S.-J. AU - Fearon, W.F. AU - Escaned, J. AU - Park, S.-J. TI - Practical Application of Coronary Physiologic Assessment: Asia-Pacific Expert Consensus Document: Part 1 JF - JACC: ASIA J2 - JACC VL - 3 PY - 2023 IS - 5 SP - 689 EP - 706 PG - 18 SN - 2772-3747 DO - 10.1016/j.jacasi.2023.07.003 UR - https://m2.mtmt.hu/api/publication/34283190 ID - 34283190 N1 - Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, South Korea Division of Cardiology, Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan Department of Internal Medicine, Chonnam National University Hospital, Gwangju, South Korea Department of Cardiovascular Medicine, Gifu Heart Center, Gifu, Japan Division of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea Department of Cardiology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea Department of Cardiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China Biomedical Instrument Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China The Lambe Institute for Translational Medicine, The Smart Sensors Lab and Curam, National University of Ireland, University Road, Galway, Ireland Division of Cardiology, Department of Medicine, University of Verona, Verona, Italy Yong Loo Lin School of Medicine, National University of Singapore, Singapore; National University Heart Centre, National University Health System, Singapore Department of Cardiology, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan Department of Internal Medicine and Cardiovascular Research Institute, Keimyung University Dongsan Hospital, Daegu, South Korea Department of Cardiology, Concord Hospital, University of Sydney, Sydney, Australia Department of Cardiology, Wellington Hospital, Wellington, New Zealand Department of Cardiology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Department of Cardiology, Cardiac Vascular Sentral KL (CVSKL), Kuala Lumpur, Malaysia Department of Cardiology, Madras Medical Mission, Chennai, India Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou and Chang Gung University College of Medicine, Taoyuan, Taiwan Division of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Ibaraki, Japan Department of Cardiology, Ajou University Medical Center, Suwon, South Korea Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, United States Hospital Clinico San Carlos IDISSC, Complutense University of Madrid, Madrid, Spain Cited By :1 Export Date: 9 November 2023 Correspondence Address: Koo, B.-K.; Department of Internal Medicine and Cardiovascular Center, 101 Daehang-ro, Chongno-gu, South Korea; email: bkkoo@snu.ac.kr AB - Coronary physiologic assessment is performed to measure coronary pressure, flow, and resistance or their surrogates to enable the selection of appropriate management strategy and its optimization for patients with coronary artery disease. The value of physiologic assessment is supported by a large body of evidence that has led to major recommendations in clinical practice guidelines. This expert consensus document aims to convey practical and balanced recommendations and future perspectives for coronary physiologic assessment for physicians and patients in the Asia-Pacific region based on updated information in the field that including both wire- and image-based physiologic assessment. This is Part 1 of the whole consensus document, which describes the general concept of coronary physiology, as well as practical information on the clinical application of physiologic indices and novel image-based physiologic assessment. © 2023 The Authors LA - English DB - MTMT ER -