@article{MTMT:34959260, title = {Revealing the role of material properties in impact-related injuries: Investigating the influence of brain and skull density variations on head injury severity}, url = {https://m2.mtmt.hu/api/publication/34959260}, author = {Abdi, Hamed and Sanchez-Molina, David and Garcia-Vilana, Silvia and Rahimi-Movaghar, Vafa}, doi = {10.1016/j.heliyon.2024.e29427}, journal-iso = {HELIYON}, journal = {HELIYON}, volume = {10}, unique-id = {34959260}, keywords = {DENSITY; VISCOELASTIC MATERIALS; Finite element model (FEM); injury prevention; traumatic brain injuries (TBI); head impact; Head injury criterion (HIC)}, year = {2024}, eissn = {2405-8440}, orcid-numbers = {Abdi, Hamed/0000-0002-5198-261X} } @article{MTMT:34959314, title = {Nervous System Response to Neurotrauma: A Narrative Review of Cerebrovascular and Cellular Changes After Neurotrauma}, url = {https://m2.mtmt.hu/api/publication/34959314}, author = {Ali, Hossam Tharwat and Sula, Idris and AbuHamdia, Abrar and Elejla, Sewar A. and Elrefaey, Ahmed and Hamdar, Hiba and Elfil, Mohamed}, doi = {10.1007/s12031-024-02193-8}, journal-iso = {J MOL NEUROSCI}, journal = {JOURNAL OF MOLECULAR NEUROSCIENCE}, volume = {74}, unique-id = {34959314}, issn = {0895-8696}, keywords = {Blood-Brain Barrier; traumatic brain injury; neuroinflammation; Neurotrauma; CEREBROVASCULAR AUTOREGULATION}, year = {2024}, eissn = {1559-1166}, orcid-numbers = {Ali, Hossam Tharwat/0000-0001-8077-5911; AbuHamdia, Abrar/0000-0002-8653-9984; Hamdar, Hiba/0000-0002-4488-7323; Elfil, Mohamed/0000-0002-1125-2946} } @article{MTMT:34560236, title = {Epidemiology of Traumatic Brain Injury in Abu-Dhabi, UAE}, url = {https://m2.mtmt.hu/api/publication/34560236}, author = {Alqaydi, K. and Ghazanfar, O. and Madhi, A. and Avila, N. and Fares, S.}, doi = {10.2174/0250688205666230906092948}, journal-iso = {EMIRATES MED J}, journal = {EMIRATES MEDICAL JOURNAL}, volume = {5}, unique-id = {34560236}, issn = {0250-6882}, year = {2024} } @article{MTMT:34959295, title = {Quantitative Electroencephalographic Changes Associated With Brain Tissue Hypoxia After Pediatric Traumatic Brain Injury: A Retrospective Exploratory Analysis}, url = {https://m2.mtmt.hu/api/publication/34959295}, author = {Appavu, Brian L. and Temkit, MHamed and Hanalioglu, Damla and Burrows, Brian T. and Adelson, P. David}, doi = {10.1097/WNP.0000000000001015}, journal-iso = {J CLIN NEUROPHYSIOL}, journal = {JOURNAL OF CLINICAL NEUROPHYSIOLOGY}, volume = {41}, unique-id = {34959295}, issn = {0736-0258}, keywords = {traumatic brain injury; near-infrared spectroscopy; Early posttraumatic seizures; Multimodality neurologic monitoring}, year = {2024}, eissn = {1537-1603}, pages = {214-220} } @article{MTMT:34959287, title = {A Comprehensive and Broad Approach to Resting-State Functional Connectivity in Adult Patients with Mild Traumatic Brain Injury}, url = {https://m2.mtmt.hu/api/publication/34959287}, author = {Arabshahi, Soroush and Chung, Sohae and Alivar, Alaleh and Amorapanth, Prin X. and Flanagan, Steven R. and Foo, Farng-Yang A. and Laine, Andrew F. and Lui, Yvonne W.}, doi = {10.3174/ajnr.A8193}, journal-iso = {AM J NEURORADIOL}, journal = {AMERICAN JOURNAL OF NEURORADIOLOGY}, unique-id = {34959287}, issn = {0195-6108}, year = {2024}, eissn = {1936-959X}, orcid-numbers = {Arabshahi, Soroush/0000-0003-3017-6392; Chung, Sohae/0000-0002-1132-900X; Alivar, Alaleh/0000-0002-9123-1079} } @article{MTMT:35326382, title = {Prognostic value of systemic immune-inflammation index, neutrophil-lymphocyte ratio, and thrombocyte-lymphocyte ratio in critically ill patients with moderate to severe traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/35326382}, author = {Arslan, Kadir and Sahin, Ayca Sultan}, doi = {10.1097/MD.0000000000039007}, journal-iso = {MEDICINE}, journal = {MEDICINE}, volume = {103}, unique-id = {35326382}, issn = {0025-7974}, keywords = {MORTALITY; traumatic brain injury; biomarker; Systemic immune-inflammation index; Neutrophil-to-lymphocyte ratio}, year = {2024}, eissn = {1536-5964} } @article{MTMT:34307884, title = {Low-dose ionizing radiation promotes motor recovery and brain rewiring by resolving inflammatory response after brain injury and stroke}, url = {https://m2.mtmt.hu/api/publication/34307884}, author = {Au, Ngan Pan Bennett and Wu, Tan and Kumar, Gajendra and Jin, Yuting and Li, Yolanda Yuen Tung and Chan, Shun Lam and Lai, Joseph Ho Chi and Chan, Kannie Wai Yan and Yu, Kwan Ngok and Wang, Xin and Ma, Chi Him Eddie}, doi = {10.1016/j.bbi.2023.09.015}, journal-iso = {BRAIN BEHAV IMMUN}, journal = {BRAIN BEHAVIOR AND IMMUNITY}, volume = {115}, unique-id = {34307884}, issn = {0889-1591}, abstract = {Traumatic brain injury (TBI) and stroke share a common pathophysiology that worsens over time due to sec-ondary tissue injury caused by sustained inflammatory response. However, studies on pharmacological in-terventions targeting the complex secondary injury cascade have failed to show efficacy. Here, we demonstrated that low-dose ionizing radiation (LDIR) reduced lesion size and reversed motor deficits after TBI and photo -thrombotic stroke. Magnetic resonance imaging demonstrated significant reduction of infarct volume in LDIR-treated mice after stroke. Systems-level transcriptomic analysis showed that genes upregulated in LDIR-treated stoke mice were enriched in pathways associated with inflammatory and immune response involving micro-glia. LDIR induced upregulation of anti-inflammatory-and phagocytosis-related genes, and downregulation of key pro-inflammatory cytokine production. These findings were validated by live-cell assays, in which microglia exhibited higher chemotactic and phagocytic capacities after LDIR. We observed substantial microglial clustering at the injury site, glial scar clearance and reversal of motor deficits after stroke. Cortical microglia/macrophages depletion completely abolished the beneficial effect of LDIR on motor function recovery in stroke mice. LDIR promoted axonal projections (brain rewiring) in motor cortex and recovery of brain activity detected by elec-troencephalography recordings months after stroke. LDIR treatment delayed by 8 h post-injury still maintained full therapeutic effects on motor recovery, indicating that LDIR is a promising therapeutic strategy for TBI and stroke.}, keywords = {traumatic brain injury; low-dose ionizing radiation; photothrombotic stroke; Microglia polarization}, year = {2024}, eissn = {1090-2139}, pages = {43-63}, orcid-numbers = {Au, Ngan Pan Bennett/0000-0003-0245-9096} } @article{MTMT:35326363, title = {Molecular Pathway Changes Associated with Different Post-Conditioning Exercise Interventions After Experimental TBI}, url = {https://m2.mtmt.hu/api/publication/35326363}, author = {Barrett, James P. and Aubrecht, Taryn G. and Smith, Aidan and Vaida, Maria and Henry, Rebecca J. and Doran, Sarah J. and Faden, Alan I. and Stoica, Bogdan A.}, doi = {10.1089/neu.2024.0120}, journal-iso = {J NEUROTRAUM}, journal = {JOURNAL OF NEUROTRAUMA}, unique-id = {35326363}, issn = {0897-7151}, keywords = {Inflammation; Exercise; neuroprotection; microglia; brain injury}, year = {2024}, eissn = {1557-9042} } @article{MTMT:34931343, title = {Chitosan revokes controlled-cortical impact generated neurological aberrations in circadian disrupted mice via TLR4-NLRP3 axis}, url = {https://m2.mtmt.hu/api/publication/34931343}, author = {Bazaz, Mohd Rabi and Asthana, Amit and Dandekar, Manoj P.}, doi = {10.1016/j.ejphar.2024.176436}, journal-iso = {EUR J PHARMACOL}, journal = {EUROPEAN JOURNAL OF PHARMACOLOGY}, volume = {969}, unique-id = {34931343}, issn = {0014-2999}, keywords = {TLR4; GFAP; Chitosan; TBI; CCI; NLRP3; Circadian disruption}, year = {2024}, eissn = {1879-0712}, orcid-numbers = {Asthana, Amit/0000-0002-3419-884X} } @article{MTMT:34959281, title = {Traumatic brain injury and occupational risk of low-level blast exposure on adverse career outcomes: an examination of administrative and medical separations from Service (2005-2015)}, url = {https://m2.mtmt.hu/api/publication/34959281}, author = {Belding, Jennifer N. and Bonkowski, James and Englert, Robyn}, doi = {10.3389/fneur.2024.1389757}, journal-iso = {FRONT NEUR}, journal = {FRONTIERS IN NEUROLOGY}, volume = {15}, unique-id = {34959281}, issn = {1664-2295}, keywords = {BLAST; EPIDEMIOLOGY; traumatic brain injury; concussion; job loss; military; low-level blast; medical separation}, year = {2024}, eissn = {1664-2295} } @article{MTMT:35314377, title = {Neuroforensomics: metabolites as valuable biomarkers in cerebrospinal fluid of lethal traumatic brain injuries}, url = {https://m2.mtmt.hu/api/publication/35314377}, author = {Bohnert, Simone and Reinert, Christoph and Trella, Stefanie and Cattaneo, Andrea and Preiss, Ulrich and Bohnert, Michael and Zwirner, Johann and Buettner, Andreas and Schmitz, Werner and Ondruschka, Benjamin}, doi = {10.1038/s41598-024-64312-0}, journal-iso = {SCI REP}, journal = {SCIENTIFIC REPORTS}, volume = {14}, unique-id = {35314377}, issn = {2045-2322}, keywords = {cerebrospinal fluid; traumatic brain injury; biomarker; Forensic neuropathology; post mortem biochemistry}, year = {2024}, eissn = {2045-2322}, orcid-numbers = {Cattaneo, Andrea/0009-0009-7489-4987} } @article{MTMT:34766161, title = {Deplete and repeat: microglial CSF1R inhibition and traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/34766161}, author = {Boland, R. and Kokiko-Cochran, O.N.}, doi = {10.3389/fncel.2024.1352790}, journal-iso = {FRONT CELL NEUROSCI}, journal = {FRONTIERS IN CELLULAR NEUROSCIENCE}, volume = {18}, unique-id = {34766161}, issn = {1662-5102}, abstract = {Traumatic brain injury (TBI) is a public health burden affecting millions of people. Sustained neuroinflammation after TBI is often associated with poor outcome. As a result, increased attention has been placed on the role of immune cells in post-injury recovery. Microglia are highly dynamic after TBI and play a key role in the post-injury neuroinflammatory response. Therefore, microglia represent a malleable post-injury target that could substantially influence long-term outcome after TBI. This review highlights the cell specific role of microglia in TBI pathophysiology. Microglia have been manipulated via genetic deletion, drug inhibition, and pharmacological depletion in various pre-clinical TBI models. Notably, colony stimulating factor 1 (CSF1) and its receptor (CSF1R) have gained much traction in recent years as a pharmacological target on microglia. CSF1R is a transmembrane tyrosine kinase receptor that is essential for microglia proliferation, differentiation, and survival. Small molecule inhibitors targeting CSF1R result in a swift and effective depletion of microglia in rodents. Moreover, discontinuation of the inhibitors is sufficient for microglia repopulation. Attention is placed on summarizing studies that incorporate CSF1R inhibition of microglia. Indeed, microglia depletion affects multiple aspects of TBI pathophysiology, including neuroinflammation, oxidative stress, and functional recovery with measurable influence on astrocytes, peripheral immune cells, and neurons. Taken together, the data highlight an important role for microglia in sustaining neuroinflammation and increasing risk of oxidative stress, which lends to neuronal damage and behavioral deficits chronically after TBI. Ultimately, the insights gained from CSF1R depletion of microglia are critical for understanding the temporospatial role that microglia develop in mediating TBI pathophysiology and recovery. Copyright © 2024 Boland and Kokiko-Cochran.}, keywords = {Oxygen Consumption; APOPTOSIS; PHAGOCYTOSIS; CYTOKINE PRODUCTION; DEPRESSION; review; human; Survival Analysis; Cell Differentiation; Quality of Life; membrane protein; innate immunity; nonhuman; cell proliferation; sexual behavior; memory disorder; brain cortex; Electroencephalography; sleep disorder; POSTSYNAPTIC DENSITY; somatosensory cortex; glial fibrillary acidic protein; Spatial learning; Gene Expression; Gene Deletion; Ischemic Preconditioning; cardiovascular function; outcome assessment; unclassified drug; interleukin 6; interleukin 10; ion channel; Tumor Necrosis Factor; immunocompetent cell; CD11b antigen; brain blood flow; headache; traumatic brain injury; traumatic brain injury; mitochondrial DNA; head injury; excitotoxicity; anxiety; Parkinson disease; working memory; CURCUMIN; demyelination; neuroinflammation; microglia; microglia; immunoglobulin enhancer binding protein; Fluid percussion injury; transcription initiation; cytokine release; monocyte chemotactic protein 1; interleukin 1beta; degenerative disease; Alzheimer disease; blood brain barrier; sleep time; Aquaporin 4; Endoplasmic reticulum stress; colony stimulating factor 1; neurotransmitter receptor; physiological stress; ASTROCYTE; blood vessel injury; brain injury; Genetic manipulation; skull fracture; cytokine receptor; spinal cord injury; antibody labeling; nervous system inflammation; emergency ward; tyrosine kinase receptor; embryo development; GLUTAMATE TRANSPORTER; purinergic P2Y12 receptor; cannabidiol; clodronic acid; ginseng; Controlled cortical impact; mortality rate; TUNEL assay; toll like receptor 1; neuroinflammatory response; Morris water maze test; Behavioral changes; n sec butyl 1 (2 chlorophenyl) n methyl 3 isoquinolinecarboxamide; CSF1R; Minocycline; chemokine receptor CX3CR1; CD135 antigen; caspase 11; CD68 antigen; ionized calcium binding adapter molecule 1; novel object recognition test; PLX5622; pexidartinib; oligodendrocyte culture; mechanical trauma; Oxidative stress; ncf1 protein; Novel object recognition memory; Neurological Severity Score; sotuletinib; damage-associated molecular pattern-triggered immunity; peripheral immune cell; gw 2580 inhibitor; Ki20227 inhibitor; plx 5622 inhibitor; plx 647 inhibitor; Closed Head Impact Model of Engineered Rotational Acceleration; mechanical sleep fragmentation; phagocytosing oligodendrocyte; weight drop injury}, year = {2024}, eissn = {1662-5102} } @article{MTMT:34555885, title = {Clinical outcomes for various benign paroxysmal positional vertigo (BPPV) diagnoses in adolescents and young adults with recent concussions}, url = {https://m2.mtmt.hu/api/publication/34555885}, author = {Bowman, Thomas G. and Thibault, Rachel and Radack, Benjamin M. and Davis, Anissa and Elam, Penelope}, doi = {10.1016/j.ptsp.2023.12.004}, journal-iso = {PHYS THER SPORT}, journal = {PHYSICAL THERAPY IN SPORT}, volume = {65}, unique-id = {34555885}, issn = {1466-853X}, abstract = {Objective: Determine how positive BPPV findings in adolescents and young adults following concussion impacted the total number of treatments required and time until discharge. Setting: Outpatient physical therapy clinic.Participants: 167 individuals who were diagnosed with concussion or brain injury.Design: Retrospective chart review. Main measures: Total number of treatments and days until discharge were compared for various BPPV diagnoses (anterior canal, posterior canal, horizontal canal, and combination) and for individuals with and without BPPV.Results: Fifty-one out of 167 cases (30.54%) were diagnosed with BPPV. The total number of treatments provided was statistically different across BPPV diagnoses (P = .004). However, days until discharge were not statistically different between BPPV diagnoses (P = .28). There was no significant difference between time to discharge between those with BPPV (median = 21 days, range = 7-126) and those without (median = 28 days, range = 7-84 days; P = .23, r = 0.09).Conclusion: To optimize outcomes, including symptom resolution and return to sport and/or work, early identification of BPPV and subsequent intervention should be prioritized for individuals who have concussion symptoms that suggest vestibular dysfunction.}, keywords = {Therapy; rehabilitation; rehabilitation; vestibular dysfunction; concussion; BPPV}, year = {2024}, pages = {90-94} } @article{MTMT:34560215, title = {Traumatic brain injury is common and undertreated in the orthopaedic trauma population}, url = {https://m2.mtmt.hu/api/publication/34560215}, author = {Boyapati, R.M. and Nehrbas, J. and Yarboro, S.R. and Hadeed, M.M.}, doi = {10.1016/j.injury.2024.111325}, journal-iso = {INJURY}, journal = {INJURY: INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED}, volume = {55}, unique-id = {34560215}, issn = {0020-1383}, year = {2024}, eissn = {1879-0267} } @article{MTMT:34959298, title = {Exploring Discussions About Virtual Reality on Twitter to Inform Brain Injury Rehabilitation: Content and Network Analysis}, url = {https://m2.mtmt.hu/api/publication/34959298}, author = {Brassel, Sophie and Brunner, Melissa and Campbell, Andrew and Power, Emma and Togher, Leanne}, doi = {10.2196/45168}, journal-iso = {J MED INTERNET RES}, journal = {JOURNAL OF MEDICAL INTERNET RESEARCH}, volume = {26}, unique-id = {34959298}, issn = {1438-8871}, keywords = {INJURY; Development; clinical practice; Virtual reality; Social networks; brain injury; rehabilitation; USERS; engagement; Twitter; Social media; Cognitive communication; brain injury rehabilitation}, year = {2024}, orcid-numbers = {Brunner, Melissa/0000-0001-6823-5189; Power, Emma/0000-0002-2638-0406} } @article{MTMT:34959285, title = {Mental Illness in the 2 Years Prior to Pregnancy in a Population With Traumatic Brain Injury: A Cross-Sectional Study: La maladie mentale dans les deux ans précédant une grossesse dans une population souffrant de lésion cérébrale traumatique : une étude transversale}, url = {https://m2.mtmt.hu/api/publication/34959285}, author = {Brown, Hilary K. and Strauss, Rachel and Fung, Kinwah and Mataruga, Andrea and Chan, Vincy and Mollayeva, Tatyana and Urbach, Natalie and Colantonio, Angela and Cohen, Eyal and Dennis, Cindy-Lee and Ray, Joel G. and Saunders, Natasha and Vigod, Simone N.}, doi = {10.1177/07067437241249957}, journal-iso = {CAN J PSYCHIAT}, journal = {CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE}, unique-id = {34959285}, issn = {0706-7437}, keywords = {WOMEN; Cohort Studies; Brain Injuries; mental health; Preconception Care; l & eacute;sions c & eacute;r & eacute;brales; & eacute;tudes de cohorte; sant & eacute; mentale; soins pr & eacute;conceptionnels; femmes}, year = {2024}, eissn = {1497-0015}, orcid-numbers = {Dennis, Cindy-Lee/0000-0002-0135-7242} } @article{MTMT:35326386, title = {Classification of short and long term mild traumatic brain injury using computerized eye tracking}, url = {https://m2.mtmt.hu/api/publication/35326386}, author = {Cade, Alice and Turnbull, Philip R. K.}, doi = {10.1038/s41598-024-63540-8}, journal-iso = {SCI REP}, journal = {SCIENTIFIC REPORTS}, volume = {14}, unique-id = {35326386}, issn = {2045-2322}, keywords = {Reproducibility of Results; machine learning; brain concussion; Post-Concussion Syndrome; Ocular motility disorders}, year = {2024}, eissn = {2045-2322}, orcid-numbers = {Cade, Alice/0000-0002-3050-3958} } @article{MTMT:34959270, title = {Analysis of risk factors and development of predictive model for malnutrition in patients with traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/34959270}, author = {Cai, Ang and Li, Yi and Xi, Xiao and Wang, Qingmei and Yang, Junfeng and Wang, Liugen and Li, Heping and Luo, Xun and Zeng, Xi}, doi = {10.1080/1028415X.2024.2342152}, journal-iso = {NUTR NEUROSCI}, journal = {NUTRITIONAL NEUROSCIENCE}, unique-id = {34959270}, issn = {1028-415X}, keywords = {risk factor; traumatic brain injury; dysphagia; malnutrition; nomogram; Prediction Model; pulmonary infection; eating pattern}, year = {2024}, eissn = {1476-8305} } @article{MTMT:34959302, title = {Emotional Resilience Predicts Preserved White Matter Microstructure Following Mild Traumatic Brain Injury}, url = {https://m2.mtmt.hu/api/publication/34959302}, author = {Cai, Lanya T. and Brett, Benjamin L. and Palacios, Eva M. and Yuh, Esther L. and Bourla, Ioanna and Wren-Jarvis, Jamie and Wang, Yang and Mac Donald, Christine and Diaz-Arrastia, Ramon and Giacino, Joseph T. and Okonkwo, David O. and Levin, Harvey S. and Robertson, Claudia S. and Temkin, Nancy and Markowitz, Amy J. and Manley, Geoffrey T. and Stein, Murray B. and Mccrea, Michael A. and Zafonte, Ross D. and Nelson, Lindsay D. and Mukherjee, Pratik}, doi = {10.1016/j.bpsc.2022.08.015}, journal-iso = {BIOLOGICAL PSYCHIATRY: COGNITIVE NEUROSCIENCE AND NEUROIMAGINING}, journal = {BIOLOGICAL PSYCHIATRY: COGNITIVE NEUROSCIENCE AND NEUROIMAGING}, volume = {9}, unique-id = {34959302}, issn = {2451-9022}, year = {2024}, eissn = {2451-9030}, pages = {164-175} } @article{MTMT:35326399, title = {Association of Central Nervous System-Affecting Medications With Occurrence and Short-Term Mortality of Traumatic Brain Injury}, url = {https://m2.mtmt.hu/api/publication/35326399}, author = {Cajanus, Kristiina and Kyto, Ville and Ruuskanen, Jori O. and Luoto, Teemu M. and Rautava, Paivi and Tornio, Aleksi and Posti, Jussi P.}, doi = {10.1227/neu.0000000000002732}, journal-iso = {NEUROSURGERY}, journal = {NEUROSURGERY}, volume = {94}, unique-id = {35326399}, issn = {0148-396X}, keywords = {MORTALITY; EPIDEMIOLOGY; traumatic brain injury; Central nervous system medications}, year = {2024}, eissn = {1524-4040}, pages = {721-728}, orcid-numbers = {Kyto, Ville/0000-0002-4521-1093; Tornio, Aleksi/0000-0001-5713-5692} } @article{MTMT:34959280, title = {Clinico-radiological correlation with outcome in acute epidural haematoma: a tertiary centre experience from Nepal}, url = {https://m2.mtmt.hu/api/publication/34959280}, author = {Chakradhar, Rupesh and Harrylal, Kayleigh Anjali and Kumari, Khusbu and Karki, Susmin and Sedain, Gopal and Pradhanang, Amit and Shilpakar, Sushil K. and Sharma, Mohan Raj}, doi = {10.1097/MS9.0000000000002018}, journal-iso = {ANN MED SURG}, journal = {ANNALS OF MEDICINE AND SURGERY}, volume = {86}, unique-id = {34959280}, issn = {2049-0801}, keywords = {traumatic brain injury; neurosurgery; Modified Rankin Scale; Epidural haematoma}, year = {2024}, pages = {2446-2452}, orcid-numbers = {Karki, Susmin/0000-0002-8570-5223} } @article{MTMT:34959297, title = {Pulmonary Effects of Traumatic Brain Injury in Mice: A Gene Set Enrichment Analysis}, url = {https://m2.mtmt.hu/api/publication/34959297}, author = {Chan, Wei-Hung and Huang, Shih-Ming and Chiu, Yi-Lin}, doi = {10.3390/ijms25053018}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {25}, unique-id = {34959297}, issn = {1661-6596}, keywords = {traumatic brain injury; Acute lung injury; Immune cell infiltration; brain lung interaction}, year = {2024}, eissn = {1422-0067}, orcid-numbers = {Chan, Wei-Hung/0000-0001-5514-8932; Huang, Shih-Ming/0000-0001-9305-921X} } @article{MTMT:34721376, title = {Effects of bone marrow mesenchymal stromal cells-derived therapies for experimental traumatic brain injury: A meta-analysis}, url = {https://m2.mtmt.hu/api/publication/34721376}, author = {Chen, C. and Peng, C. and Hu, Z. and Ge, L.}, doi = {10.1016/j.heliyon.2024.e25050}, journal-iso = {HELIYON}, journal = {HELIYON}, volume = {10}, unique-id = {34721376}, abstract = {Background: Bone-marrow-derived mesenchymal stromal (stem) cells [also called MSC(M)] and their extracellular vesicles (EVs) are considered a potentially innovative form of therapy for traumatic brain injury (TBI). Nevertheless, their application to TBI particularly remains preclinical, and the effects of these cells remain unclear and controversial. Therefore, an updated meta-analysis of preclinical studies is necessary to assess the effectiveness of MSC(M) and MSC(M) derived EVs in clinical trials. Methods: The following databases were searched (to December 2022): PubMed, Web of Science, and Embase. In this study, we measured functional outcomes based on the modified neurological severity score (mNSS), cognitive outcomes based on the Morris water maze (MWM), and histopathological outcomes based on lesion volume. A random effects meta-analysis was conducted to evaluate the effect of mNSS, MWM, and lesion volume. Results: A total of 2163 unique records were identified from our search, with Fifty-five full-text articles satisfying inclusion criteria. A mean score of 5.75 was assigned to the studies’ quality scores, ranging from 4 to 7. MSC(M) and MSC(M) derived EVs had an overall positive effect on the mNSS score and MWM with SMDs −2.57 (95 % CI -3.26; −1.88; p < 0.01) and - 2.98 (95 % CI -4.21; −1.70; p < 0.01), respectively. As well, MSC(M) derived EVs were effective in reducing lesion volume by an SMD of - 0.80 (95 % CI -1.20; −0.40; p < 0.01). It was observed that there was significant variation among the studies, but further analyses could not determine the cause of this heterogeneity. Conclusions: MSC(M) and MSC(M) derived EVs are promising treatments for TBI in pre-clinical studies, and translation to the clinical domain appears warranted. Besides, large-scale trials in animals and humans are required to support further research due to the limited sample size of MSC(M) derived EVs. © 2024}, keywords = {animal model; Meta-analysis; traumatic brain injury; Extracellular vesicles; bone marrow stromal cell (BMSC)}, year = {2024}, eissn = {2405-8440} } @article{MTMT:34560209, title = {The value of computed tomography angiography in predicting the surgical effect and prognosis of severe traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/34560209}, author = {Chen, J. and Zhao, W. and Zhu, X. and Yang, L. and Geng, C. and Zhang, X. and Wang, Y.}, doi = {10.1038/s41598-024-52385-w}, journal-iso = {SCI REP}, journal = {SCIENTIFIC REPORTS}, volume = {14}, unique-id = {34560209}, issn = {2045-2322}, year = {2024}, eissn = {2045-2322} } @article{MTMT:35326383, title = {Efficacy of rTMS combined with cognitive training in TBI with cognition disorder: a systematic review and meta-analysis}, url = {https://m2.mtmt.hu/api/publication/35326383}, author = {Chen, Jia and Dong, Yuanwei and Guo, Hong and Zhao, Tianyu and Zhang, Di and Jin, Song}, doi = {10.1007/s10072-024-07530-8}, journal-iso = {NEUROL SCI}, journal = {NEUROLOGICAL SCIENCES}, volume = {45}, unique-id = {35326383}, issn = {1590-1874}, keywords = {cognition; Meta-analysis; systematic review; TBI; RTMS; PTBICD}, year = {2024}, eissn = {1590-3478}, pages = {3683-3697}, orcid-numbers = {Zhang, Di/0009-0007-7061-981X} } @article{MTMT:35185102, title = {LncRNA H19 knockdown promotes neuropathologic and functional recovery via the Nrf2/HO-1 axis after traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/35185102}, author = {Chen, Q. and Wu, B. and Shi, Z. and Wang, Y. and Yuan, Y. and Chen, X. and Wang, Y. and Hu, J. and Mao, L. and Gao, Y. and Wu, G.}, doi = {10.1111/cns.14870}, journal-iso = {CNS NEUROSCI THER}, journal = {CNS NEUROSCIENCE & THERAPEUTICS}, volume = {30}, unique-id = {35185102}, issn = {1755-5930}, abstract = {Aims: Traumatic brain injury (TBI) stands as a significant concern in public health, frequently leading to enduring neurological deficits. Long non-coding RNA H19 (lncRNA H19) exerts a potential regulator role in the pathology of brain injury. This study investigates the effects of lncRNA H19 knockdown (H19-KD) on the pathophysiology of TBI and its potential neuroprotective mechanisms. Methods: Controlled cortical impact was employed to establish a stable TBI mouse model. The expression levels of various genes in perilesional cortex and striatum tissue after TBI was detected by RT-qPCR. AAV9-shRNA-H19 was injected into the lateral ventricle of mice to knockdown the expression of lncRNA H19. Various behavioral tests were performed to evaluate sensorimotor and cognitive functions after TBI. Immunofluorescence and Nissl staining were performed to assess brain tissue damage and neuroinflammation. The Nrf2 and HO-1 expression was performed by Western blot. Results: After TBI, the expression of lncRNA H19 was elevated in perilesional tissue and gradually reverted to baseline. Behavioral tests demonstrated that H19-KD significantly promoted the recovery of sensorimotor and cognitive functions after TBI. Besides, H19-KD reduced brain tissue loss, preserved neuronal integrity, and ameliorated white matter damage at the histological level. In addition, H19-KD restrained the pro-inflammatory and facilitated anti-inflammatory phenotypes of microglia/macrophages, attenuating the neuroinflammatory response after TBI. Furthermore, H19-KD promoted activation of the Nrf2/HO-1 axis after TBI, while suppression of Nrf2 partially abolished the neuroprotective effect. Conclusion: H19-KD exerts neuroprotective effects after TBI in mice, partially mediated by the activation of the Nrf2/HO-1 axis. © 2024 The Author(s). CNS Neuroscience & Therapeutics published by John Wiley & Sons Ltd.}, keywords = {Animals; Adult; Male; Male; Inflammation; APOPTOSIS; metabolism; MICE; PHENOTYPE; GENETICS; NEUROPATHOLOGY; PHARMACOLOGY; immunohistochemistry; hippocampus; ARTICLE; PATHOPHYSIOLOGY; MOUSE; signal transduction; animal; Mice, Inbred C57BL; Cell Differentiation; Membrane Proteins; Quality of Life; MACROPHAGE; physiology; membrane protein; controlled study; Nerve Degeneration; nonhuman; animal tissue; animal model; animal experiment; pathology; Histology; brain ischemia; brain hemorrhage; cognition; brain tissue; corpus striatum; Western blotting; public health; protein expression; interleukin 6; tissue injury; traumatic brain injury; traumatic brain injury; acetylsalicylic acid; MOUSE MODEL; neuroprotection; neuroprotection; immunofluorescence; brain edema; demyelination; microglia; Craniotomy; upregulation; muscle strength; C57BL mouse; interleukin 1beta; cognitive defect; degenerative disease; white matter; HYPOXIA; CARCINOGENESIS; blood brain barrier; real time polymerase chain reaction; Heme Oxygenase-1; Drug therapy; Recovery of Function; heme oxygenase 1; ASTROCYTE; genetic transcription; brain injury; convalescence; spinal cord injury; Nrf2; nervous system inflammation; Middle cerebral artery occlusion; tau protein; Gene Knockdown Techniques; pyramidal tract; transcription factor Nrf2; transcription factor Nrf2; corpus callosum; RNA H19; long untranslated RNA; long untranslated RNA; basic leucine zipper transcription factor; procedures; RNA, Long Noncoding; concussion; gene knockdown; gene knockdown; Brain Injuries, Traumatic; remyelinization; rotarod test; NF-E2-Related Factor 2; nissl staining; astrocytosis; adeno associated virus vector; arginase 1; brain lateral ventricle; Nfe2l2 protein, mouse; novel object recognition test; Hmox1 protein, mouse; diffuse brain injury; Oxidative stress; long non-coding RNA H19; H19 long non-coding RNA}, year = {2024}, eissn = {1755-5949} } @article{MTMT:34951076, title = {Extracellular vesicles as carriers for noncoding RNA-based regulation of macrophage/microglia polarization: an emerging candidate regulator for lung and traumatic brain injuries}, url = {https://m2.mtmt.hu/api/publication/34951076}, author = {Chen, Zhihong and Zhang, Jingang and Pan, Yongli and Hao, Zhongnan and Li, Shuang}, doi = {10.3389/fimmu.2024.1343364}, journal-iso = {FRONT IMMUNOL}, journal = {FRONTIERS IN IMMUNOLOGY}, volume = {15}, unique-id = {34951076}, issn = {1664-3224}, keywords = {traumatic brain injury; Extracellular vesicles; Noncoding RNA; macrophage/microglia polarization; lung brain injury}, year = {2024}, eissn = {1664-3224} } @article{MTMT:34560222, title = {The neuroprotection of controlled decompression after traumatic epidural intracranial hypertension through suppression of autophagy via PI3K/Akt signaling pathway}, url = {https://m2.mtmt.hu/api/publication/34560222}, author = {Che, Y. and Wu, W. and Qian, X. and Sheng, Z. and Zhang, W. and Zheng, J. and Chen, J. and Wang, Y.}, doi = {10.1016/j.heliyon.2023.e23753}, journal-iso = {HELIYON}, journal = {HELIYON}, volume = {10}, unique-id = {34560222}, year = {2024}, eissn = {2405-8440} } @article{MTMT:35289264, title = {Diagnostic potential of IL6 and other blood-based inflammatory biomarkers in mild traumatic brain injury among children}, url = {https://m2.mtmt.hu/api/publication/35289264}, author = {Chiollaz, Anne-Cecile and Pouillard, Virginie and Habre, Celine and Seiler, Michelle and Romano, Fabrizio and Spigariol, Fabian and Schenk, Celine Ritter and Korff, Christian and Marechal, Fabienne and Wyss, Verena and Gruaz, Lyssia and Montaner, Joan and Manzano, Sergio and Sanchez, Jean-Charles}, doi = {10.3389/fneur.2024.1432217}, journal-iso = {FRONT NEUR}, journal = {FRONTIERS IN NEUROLOGY}, volume = {15}, unique-id = {35289264}, issn = {1664-2295}, keywords = {Cytokines; Biomarkers; diagnosis; emergency; Pediatric; mild traumatic brain injury (mTBI)}, year = {2024}, eissn = {1664-2295}, orcid-numbers = {Manzano, Sergio/0000-0001-9603-5520} } @article{MTMT:35326356, title = {Experience of mTBI-like symptoms in a sample without brain injury in Aotearoa/New Zealand}, url = {https://m2.mtmt.hu/api/publication/35326356}, author = {Chua, Jason and Theadom, Alice}, doi = {10.1071/IB23070}, journal-iso = {BRAIN IMPAIR}, journal = {BRAIN IMPAIRMENT}, volume = {25}, unique-id = {35326356}, issn = {1443-9646}, keywords = {INJURY; STRESS; Mild traumatic brain injury; mood; Negative affect; post-concussion symptoms; Symptom experience; illness attitudes}, year = {2024}, eissn = {1839-5252} } @article{MTMT:34959296, title = {Trending Ability of End-Tidal Capnography Monitoring During Mechanical Ventilation to Track Changes in Arterial Partial Pressure of Carbon Dioxide in Critically Ill Patients With Acute Brain Injury: A Monocenter Retrospective Study}, url = {https://m2.mtmt.hu/api/publication/34959296}, author = {Coeffic, Adrien and Joachim, Jona and Manquat, Elsa and Felliot, Elodie and Vallee, Fabrice and Mebazaa, Alexandre and Gayat, Etienne and Chousterman, Benjamin Glenn and Barthelemy, Romain}, doi = {10.1213/ANE.0000000000006553}, journal-iso = {ANESTH ANALG}, journal = {ANESTHESIA AND ANALGESIA}, volume = {138}, unique-id = {34959296}, issn = {0003-2999}, year = {2024}, eissn = {1526-7598}, pages = {607-615} } @article{MTMT:34959269, title = {Good Health-Related Quality of Life in Older Patients One Year after mTBI despite Incomplete Recovery: An Indication of the Disability Paradox?}, url = {https://m2.mtmt.hu/api/publication/34959269}, author = {Coffeng, Sophie M. and Abdulle, Amaal Eman and van der Horn, Harm J. and de Koning, Myrthe E. and ter Maaten, Jan C. and Spikman, Jacoba M. and van der Naalt, Joukje}, doi = {10.3390/jcm13092655}, journal-iso = {J CLIN MED}, journal = {JOURNAL OF CLINICAL MEDICINE}, volume = {13}, unique-id = {34959269}, keywords = {Aged; outcome assessment; Mild traumatic brain injury; health-related quality of life; OLDER}, year = {2024}, eissn = {2077-0383}, orcid-numbers = {van der Naalt, Joukje/0000-0001-9873-2418} } @article{MTMT:35270102, title = {Equity considerations in clinical practice guidelines for traumatic brain injury and the criminal justice system: A systematic review}, url = {https://m2.mtmt.hu/api/publication/35270102}, author = {Colclough, Zoe and Estrella, Maria Jennifer and Joyce, Julie Michele and Hanafy, Sara and Babineau, Jessica and Colantonio, Angela and Chan, Vincy}, doi = {10.1371/journal.pmed.1004418}, journal-iso = {PLOS MED}, journal = {PLOS MEDICINE}, volume = {21}, unique-id = {35270102}, issn = {1549-1277}, year = {2024}, eissn = {1549-1676}, orcid-numbers = {Estrella, Maria Jennifer/0000-0001-6398-0964; Babineau, Jessica/0000-0002-4770-0579} } @article{MTMT:35326357, title = {Barriers and facilitators to the assessment of cognitive-communication disorders in children and adolescents after traumatic brain injury: a survey of Australian clinical practice}, url = {https://m2.mtmt.hu/api/publication/35326357}, author = {Crumlish, L. and Copley, A. and Wallace, S. J. and Rose, T. A.}, doi = {10.1071/IB23075}, journal-iso = {BRAIN IMPAIR}, journal = {BRAIN IMPAIRMENT}, volume = {25}, unique-id = {35326357}, issn = {1443-9646}, keywords = {Measurement; clinical practice; traumatic brain injury; paediatric; Assessment; outcome measurement; Clinimetrics; cognitive-communication}, year = {2024}, eissn = {1839-5252} } @article{MTMT:35326360, title = {Targeting Circadian Protein Rev-erbα to Alleviate Inflammation, Oxidative Stress, and Enhance Functional Recovery Following Brain Trauma}, url = {https://m2.mtmt.hu/api/publication/35326360}, author = {Darmanto, Arief Gunawan and Jan, Jing-Shiun and Yen, Ting-Lin and Huang, Shin-Wei and Teng, Ruei-Dun and Wang, Jia-Yi and Taliyan, Rajeev and Sheu, Joen-Rong and Yang, Chih-Hao}, doi = {10.3390/antiox13080901}, journal-iso = {ANTIOXIDANTS-BASEL}, journal = {ANTIOXIDANTS}, volume = {13}, unique-id = {35326360}, keywords = {Inflammation; traumatic brain injury; Neuronal cell death; Oxidative stress; SR9009; SR8278}, year = {2024}, eissn = {2076-3921} } @article{MTMT:34560219, title = {Inflammation, brain connectivity, and neuromodulation in post-traumatic headache}, url = {https://m2.mtmt.hu/api/publication/34560219}, author = {da, Silva Fiorin F. and do, Espírito Santo C.C. and Da, Silva J.T. and Chung, M.-K.}, doi = {10.1016/j.bbih.2024.100723}, journal-iso = {BRAIN BEHAVIOR IMMUNITY - HEALTH}, journal = {BRAIN BEHAVIOR IMMUNITY - HEALTH}, volume = {35}, unique-id = {34560219}, issn = {2666-3546}, year = {2024}, eissn = {2666-3546} } @article{MTMT:34959261, title = {Exploring the challenges of avoiding collisions with virtual pedestrians using a dual-task paradigm in individuals with chronic moderate to severe traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/34959261}, author = {de Aquino Costa Sousa, Thiago and Gagnon, Isabelle J. and Li, Karen Z. H. and Mcfadyen, Bradford J. and Lamontagne, Anouk}, doi = {10.1186/s12984-024-01378-x}, journal-iso = {J NEUROENG REHABIL}, journal = {JOURNAL OF NEUROENGINEERING AND REHABILITATION}, volume = {21}, unique-id = {34959261}, issn = {1743-0003}, keywords = {cognition; Locomotion; Multitasking; Virtual reality; Obstacle avoidance; Circumvention; Gaze behaviour}, year = {2024}, eissn = {1743-0003} } @article{MTMT:35326381, title = {Clinical characteristics and outcomes of traumatic brain injury in patients admitted to surgical ward of Jimma Medical Center, Southwest Ethiopia: a prospective observational follow-up study}, url = {https://m2.mtmt.hu/api/publication/35326381}, author = {Dibera, Gemechis Belay and Yizengaw, Mengist Awoke and Yadeta, Gemechu Lemi and Iticha, Dinka Dugassa and Gamachu, Busha and Legesse, Bruck Tesfaye}, doi = {10.1136/bmjopen-2023-080598}, journal-iso = {BMJ OPEN}, journal = {BMJ OPEN}, volume = {14}, unique-id = {35326381}, issn = {2044-6055}, keywords = {Wound management; Trauma management; trauma nursing}, year = {2024}, eissn = {2044-6055} } @article{MTMT:34559958, title = {Long-Term Follow-Up of Critically Ill Patients With Traumatic Brain Injury: From Intensive Care Parameters to Patient and Caregiver-Reported Outcome}, url = {https://m2.mtmt.hu/api/publication/34559958}, author = {Domensino, A.-F. and Tas, J. and Donners, B. and Kooyman, J. and van, der Horst I.C.C. and Haeren, R. and Ariës, M.J.H. and van, Heugten C.}, doi = {10.1089/neu.2022.0474}, journal-iso = {J NEUROTRAUM}, journal = {JOURNAL OF NEUROTRAUMA}, volume = {41}, unique-id = {34559958}, issn = {0897-7151}, year = {2024}, eissn = {1557-9042}, pages = {123-134} } @article{MTMT:35326378, title = {The potential of gene delivery for the treatment of traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/35326378}, author = {Dooley, James and Hughes, Jasmine G. and Needham, Edward J. and Palios, Katerina A. and Liston, Adrian}, doi = {10.1186/s12974-024-03156-x}, journal-iso = {J NEUROINFLAMM}, journal = {JOURNAL OF NEUROINFLAMMATION}, volume = {21}, unique-id = {35326378}, keywords = {GENE DELIVERY; neuroimmunology; AAV; TBI}, year = {2024}, eissn = {1742-2094} } @article{MTMT:35326364, title = {Covert Consciousness in the ICU}, url = {https://m2.mtmt.hu/api/publication/35326364}, author = {Edlow, Brian L. and Menon, David K.}, doi = {10.1097/CCM.0000000000006372}, journal-iso = {CRIT CARE MED}, journal = {CRITICAL CARE MEDICINE}, volume = {52}, unique-id = {35326364}, issn = {0090-3493}, keywords = {Coma; minimally conscious state; VEGETATIVE STATE; Cognitive motor dissociation; covert consciousness; covert cortical processing}, year = {2024}, eissn = {1530-0293}, pages = {1414-1426} } @article{MTMT:34560218, title = {Pituitary dysfunction following mild traumatic brain injury in female athletes}, url = {https://m2.mtmt.hu/api/publication/34560218}, author = {Eggertsdóttir, Claessen L.Ó. and Kristjánsdóttir, H. and Jónsdóttir, M.K. and Lund, S.H. and Kristensen, I.U. and Sigurjónsdóttir, H.Á.}, doi = {10.1530/EC-23-0363}, journal-iso = {ENDOCR CONNECT}, journal = {ENDOCRINE CONNECTIONS}, volume = {13}, unique-id = {34560218}, issn = {2049-3614}, year = {2024}, eissn = {2049-3614} } @article{MTMT:34942959, title = {Mortality Predictors for Adult Patients with Mild-to-Moderate Traumatic Brain Injury: A Literature Review}, url = {https://m2.mtmt.hu/api/publication/34942959}, author = {Eghzawi, Ansam and Alsabbah, Alameen and Gharaibeh, Shatha and Alwan, Iktimal and Gharaibeh, Abeer and Goyal, Anita V.}, doi = {10.3390/neurolint16020030}, journal-iso = {NEUROL INT}, journal = {NEUROLOGY INTERNATIONAL}, volume = {16}, unique-id = {34942959}, issn = {2035-8385}, keywords = {MORTALITY; traumatic brain injury; head injury; TRAUMA; TBI}, year = {2024}, eissn = {2035-8377}, pages = {406-418}, orcid-numbers = {Alsabbah, Alameen/0000-0002-5845-3622} } @article{MTMT:34959286, title = {Allocating municipal services to individuals with complex rehabilitation needs - a discourse analysis of individual administrative decision letters}, url = {https://m2.mtmt.hu/api/publication/34959286}, author = {Ekenes, Maren and Oldeide, Olin and Wehling, Eike}, doi = {10.1186/s12913-024-10972-7}, journal-iso = {BMC HEALTH SERV RES}, journal = {BMC HEALTH SERVICES RESEARCH}, volume = {24}, unique-id = {34959286}, issn = {1472-6963}, keywords = {coordination; rehabilitation; Acquired Brain Injury; municipality; User involvement; Service allocation}, year = {2024}, eissn = {1472-6963} } @article{MTMT:35232573, title = {Longitudinal motor system changes from acute to chronic spinal cord injury}, url = {https://m2.mtmt.hu/api/publication/35232573}, author = {Emmenegger, T.M. and Pfyffer, D. and Curt, A. and Schading-Sassenhausen, S. and Hupp, M. and Ashburner, J. and Friston, K. and Weiskopf, N. and Thompson, A. and Freund, P.}, doi = {10.1111/ene.16196}, journal-iso = {EUR J NEUROL}, journal = {EUROPEAN JOURNAL OF NEUROLOGY}, volume = {31}, unique-id = {35232573}, issn = {1351-5101}, year = {2024}, eissn = {1468-1331} } @article{MTMT:34959275, title = {Lesion Frequency Distribution Maps of Traumatic Axonal Injury on Early Magnetic Resonance Imaging After Moderate and Severe Traumatic Brain Injury and Associations to 12 Months Outcome}, url = {https://m2.mtmt.hu/api/publication/34959275}, author = {Flusund, Anne-Mari Holte and Bo, Lars Eirik and Reinertsen, Ingerid and Solheim, Ole and Skandsen, Toril and Haberg, Asta and Andelic, Nada and Vik, Anne and Moen, Kent Goran}, doi = {10.1089/neu.2023.0534}, journal-iso = {J NEUROTRAUM}, journal = {JOURNAL OF NEUROTRAUMA}, unique-id = {34959275}, issn = {0897-7151}, keywords = {Brain Mapping; Artificial intelligence; neuroimaging; Diffuse axonal injury; Brain Injuries, Traumatic}, year = {2024}, eissn = {1557-9042}, orcid-numbers = {Solheim, Ole/0000-0002-5954-4817} } @article{MTMT:34959259, title = {Prediction of Initial CRP/Albumin Ratio on In-Hospital Mortality in Isolated Traumatic Brain Injury Patients}, url = {https://m2.mtmt.hu/api/publication/34959259}, author = {Friedrich, Michaela and Haferkorn, Kristin and Stein, Marco and Uhl, Eberhard and Bender, Michael}, doi = {10.3390/biomedicines12051084}, journal-iso = {BIOMEDICINES}, journal = {BIOMEDICINES}, volume = {12}, unique-id = {34959259}, keywords = {IN-HOSPITAL MORTALITY; C-reactive protein/albumin ratio; isolated traumatic brain injury; intensive care unit treatment}, year = {2024}, eissn = {2227-9059} } @article{MTMT:34959288, title = {The Australian Traumatic Brain Injury Initiative: Systematic Review and Consensus Process to Determine the Predictive Value of Demographic, Injury Event, and Social Characteristics on Outcomes for People With Moderate-Severe Traumatic Brain Injury}, url = {https://m2.mtmt.hu/api/publication/34959288}, author = {Gabbe, Belinda J. and Keeves, Jemma and Mckimmie, Ancelin and Gadowski, Adelle M. and Holland, Andrew J. and Semple, Bridgette D. and Young, Jesse T. and Crowe, Louise and Ownsworth, Tamara and Bagg, Matthew K. and Antonic-Baker, Ana and Hicks, Amelia J. and Hill, Regina and Curtis, Kate and Romero, Lorena and Ponsford, Jennie L. and Lannin, Natasha A. and O'Brien, Terence J. and Cameron, Peter A. and Cooper, D. Jamie and Rushworth, Nick and Fitzgerald, Melinda}, doi = {10.1089/neu.2023.0461}, journal-iso = {J NEUROTRAUM}, journal = {JOURNAL OF NEUROTRAUMA}, unique-id = {34959288}, issn = {0897-7151}, keywords = {Demography; common data elements; traumatic; Social factors; Outcome Assessment, Health Care; Systematic review [Publication type]; brain injuries, culture}, year = {2024}, eissn = {1557-9042}, orcid-numbers = {Romero, Lorena/0000-0001-9884-5463} } @article{MTMT:35326384, title = {Pre-injury psychiatric history, subacute symptoms and personality traits predict social reintegration at 3-month post-mild traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/35326384}, author = {Gagnon, Catherine and Trepanier, Laurence and Denault, Stephany and Lague-Beauvais, Maude and Saluja, Rajeet and Massad, Jennifer and Abouassaly, Michel and de Guise, Elaine}, doi = {10.1080/02699052.2024.2373919}, journal-iso = {BRAIN INJURY}, journal = {BRAIN INJURY}, unique-id = {35326384}, issn = {0269-9052}, keywords = {Mild traumatic brain injury; Personality; social reintegration; clinical neuropsychology; post-concussion symptoms; Psychiatric history; psychological syndrome}, year = {2024}, eissn = {1362-301X} } @article{MTMT:35326352, title = {Highly Efficient and Rapid Surface-Enhanced Raman Spectroscopy Active Platform Based on Au Nanorods for Ultrasensitive Traumatic Brain Injury Detection}, url = {https://m2.mtmt.hu/api/publication/35326352}, author = {Gao, Feng and Wang, Yanjiao and Wang, Minyue and Wang, Chengcheng and Wang, Tianwei and Wu, Jingguo and Ni, Qingbin and Sun, Baoliang and Sun, Jingyi and Wang, Ying}, doi = {10.1021/acsanm.4c00026}, journal-iso = {ACS APPL NANO MATER}, journal = {ACS APPLIED NANO MATERIALS}, unique-id = {35326352}, keywords = {SENSOR; traumatic brain injury; IL-10; SERS; S100 beta; goldnanorodarrays}, year = {2024}, eissn = {2574-0970} } @article{MTMT:34959310, title = {Nursing management of cognitive dysfunction in adults with brain injury: Summary of best evidence-practiced strategies}, url = {https://m2.mtmt.hu/api/publication/34959310}, author = {Gao, Yitian and Zhou, Wanqiong and Wang, Ying and Liu, Beixue and Liu, Jing and Wang, Qiuyi and Zhou, Lanshu}, doi = {10.1111/jocn.17058}, journal-iso = {J CLIN NURS}, journal = {JOURNAL OF CLINICAL NURSING}, unique-id = {34959310}, issn = {0962-1067}, keywords = {COGNITIVE DYSFUNCTION; brain injury; Evidence-Based Nursing; Best evidence; healthcare workers (HCWs)}, year = {2024}, eissn = {1365-2702} } @article{MTMT:35326394, title = {High school rugby coaches' knowledge and opinions of concussion in Kwa-Zulu Natal province in South Africa: an ecological cross-sectional study}, url = {https://m2.mtmt.hu/api/publication/35326394}, author = {Garnett, Daniel and Cobbing, Saul and Viljoen, Carel and Patricios, Jon}, doi = {10.1186/s13102-024-00930-5}, journal-iso = {BMC SPORTS SCI MED REHAB}, journal = {BMC SPORTS SCIENCE MEDICINE AND REHABILITATION}, volume = {16}, unique-id = {35326394}, issn = {2052-1847}, keywords = {Adolescent; Sports; injury prevention; RUGBY UNION}, year = {2024}, eissn = {2052-1847}, orcid-numbers = {Garnett, Daniel/0000-0001-5669-6121; Cobbing, Saul/0000-0002-0620-0658; Viljoen, Carel/0000-0002-3548-5509; Patricios, Jon/0000-0002-6829-4098} } @article{MTMT:35326359, title = {Outcomes following intensive day rehabilitation for young people in Western Australia}, url = {https://m2.mtmt.hu/api/publication/35326359}, author = {Gill, Irwin and Davidson, Sue-Anne and Stevenson, Paul G. and Robinson, Rae and Pool, Dayna and Valentine, Jane}, doi = {10.3233/PRM-220102}, journal-iso = {Journal of Pediatric Rehabilitation Medicine}, journal = {Journal of Pediatric Rehabilitation Medicine}, volume = {17}, unique-id = {35326359}, issn = {1874-5393}, keywords = {rehabilitation; spinal cord injury; outcome measures; Cerebral palsy; Acquired Brain Injury}, year = {2024}, eissn = {1875-8894}, pages = {167-178} } @article{MTMT:34859568, title = {The Relationship between Post-Traumatic Stress Disorder Due to Brain Injury and Glutamate Intake: A Systematic Review}, url = {https://m2.mtmt.hu/api/publication/34859568}, author = {Gruenbaum, Benjamin F. and Zlotnik, Alexander and Oleshko, Anna and Matalon, Frederic and Shiyntum, Honore N. and Frenkel, Amit and Boyko, Matthew}, doi = {10.3390/nu16060901}, journal-iso = {NUTRIENTS}, journal = {NUTRIENTS}, volume = {16}, unique-id = {34859568}, abstract = {There is a growing body of evidence that suggests a connection between traumatic brain injury (TBI) and subsequent post-traumatic stress disorder (PTSD). While the exact mechanism is unknown, we hypothesize that chronic glutamate neurotoxicity may play a role. The consumption of dietary glutamate is a modifiable factor influencing glutamate levels in the blood and, therefore, in the brain. In this systematic review, we explored the relationship between dietary glutamate and the development of post-TBI PTSD. Of the 1748 articles identified, 44 met the inclusion criteria for analysis in this review. We observed that individuals from countries with diets traditionally high in glutamate had greater odds of developing PTSD after TBI (odds ratio = 15.2, 95% confidence interval 11.69 to 19.76, p < 0.01). These findings may support the hypothesis that chronically elevated blood glutamate concentrations caused by high dietary intake invoke neurodegeneration processes that could ultimately result in PTSD. Further studies will clarify whether lowering glutamate via diet would be an effective strategy in preventing or treating post-TBI PTSD.}, keywords = {RISK; PLASMA; glutamate; DEPRESSION; SYMPTOMS; Blood-Brain Barrier; DIET; PTSD; SELF-REPORT; Post-Traumatic Stress Disorder; traumatic event; MONOSODIUM L-GLUTAMATE; ERYTHROCYTE GLUTAMATE}, year = {2024}, eissn = {2072-6643}, orcid-numbers = {Frenkel, Amit/0000-0002-4162-8406; Boyko, Matthew/0000-0003-3116-1643} } @article{MTMT:35325760, title = {Prevotella copri transplantation promotes neurorehabilitation in a mouse model of traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/35325760}, author = {Gu, Nina and Yan, Jin and Tang, Wei and Zhang, Zhaosi and Wang, Lin and Li, Zhao and Wang, Yingwen and Zhu, Yajun and Tang, Shuang and Zhong, Jianjun and Cheng, Chongjie and Sun, Xiaochuan and Huang, Zhijian}, doi = {10.1186/s12974-024-03116-5}, journal-iso = {J NEUROINFLAMM}, journal = {JOURNAL OF NEUROINFLAMMATION}, volume = {21}, unique-id = {35325760}, keywords = {traumatic brain injury; gut microbiota; Neurorehabilitation; guanosine; Prevotella copri; GUO-PI3K/Akt pathway}, year = {2024}, eissn = {1742-2094} } @article{MTMT:34560216, title = {The Role of Neuropsychology in Traumatic Brain Injury: Comprehensive Literature Review}, url = {https://m2.mtmt.hu/api/publication/34560216}, author = {Halalmeh, D.R. and Salama, H.Z. and LeUnes, E. and Feitosa, D. and Ansari, Y. and Sachwani-Daswani, G.R. and Moisi, M.D.}, doi = {10.1016/j.wneu.2023.12.069}, journal-iso = {WORLD NEUROSURG}, journal = {WORLD NEUROSURGERY}, volume = {183}, unique-id = {34560216}, issn = {1878-8750}, year = {2024}, eissn = {1878-8769}, pages = {128-143} } @article{MTMT:34949104, title = {An injectable refrigerated hydrogel for inducing local hypothermia and neuroprotection against traumatic brain injury in mice}, url = {https://m2.mtmt.hu/api/publication/34949104}, author = {Han, Yuhan and Han, Zhengzhong and Huang, Xuyang and Li, Shanshan and Jin, Guoliang and Feng, Junfeng and Wu, Decheng and Liu, Hongmei}, doi = {10.1186/s12951-024-02454-z}, journal-iso = {J NANOBIOTECHNOL}, journal = {JOURNAL OF NANOBIOTECHNOLOGY}, volume = {22}, unique-id = {34949104}, keywords = {traumatic brain injury; neuroprotection; hydrogel; local hypothermia}, year = {2024}, eissn = {1477-3155} } @article{MTMT:34555884, title = {The neuroprotective potential of phytochemicals in traumatic brain injury: mechanistic insights and pharmacological implications}, url = {https://m2.mtmt.hu/api/publication/34555884}, author = {Hasan, Gulam Mustafa and Anwar, Saleha and Shamsi, Anas and Sohal, Sukhwinder Singh and Hassan, Md. Imtaiyaz}, doi = {10.3389/fphar.2023.1330098}, journal-iso = {FRONT PHARMACOL}, journal = {FRONTIERS IN PHARMACOLOGY}, volume = {14}, unique-id = {34555884}, abstract = {Traumatic brain injury (TBI) leads to brain damage, comprising both immediate primary damage and a subsequent cascade of secondary injury mechanisms. The primary injury results in localized brain damage, while the secondary damage initiates inflammatory responses, followed by the disruption of the blood-brain barrier, infiltration of peripheral blood cells, brain edema, and the release of various immune mediators, including chemotactic factors and interleukins. TBI disrupts molecular signaling, cell structures, and functions. In addition to physical tissue damage, such as axonal injuries, contusions, and haemorrhages, TBI interferes with brain functioning, impacting cognition, decision-making, memory, attention, and speech capabilities. Despite a deep understanding of the pathophysiology of TBI, an intensive effort to evaluate the underlying mechanisms with effective therapeutic interventions is imperative to manage the repercussions of TBI. Studies have commenced to explore the potential of employing natural compounds as therapeutic interventions for TBI. These compounds are characterized by their low toxicity and limited interactions with conventional drugs. Moreover, many natural compounds demonstrate the capacity to target various aspects of the secondary injury process. While our understanding of the pathophysiology of TBI, there is an urgent need for effective therapeutic interventions to mitigate its consequences. Here, we aimed to summarize the mechanism of action and the role of phytochemicals against TBI progression. This review discusses the therapeutic implications of various phytonutrients and addresses primary and secondary consequences of TBI. In addition, we highlighted the roles of emerging phytochemicals as promising candidates for therapeutic intervention of TBI. The review highlights the neuroprotective roles of phytochemicals against TBI and the mechanistic approach. Furthermore, our efforts focused on the underlying mechanisms, providing a better understanding of the therapeutic potential of phytochemicals in TBI therapeutics.}, keywords = {glutamate; traumatic brain injury; SUBARACHNOID HEMORRHAGE; ANIMAL-MODELS; INDUCED OXIDATIVE STRESS; ENERGY HOMEOSTASIS; Blood-brain barrier (BBB); INDUCED NEUROTOXICITY; Therapeutic intervention; Functional outcomes; Phytonutrients; ACID PHENETHYL ESTER; multi-targeted therapies; secondary injury cascades (SIC); AMELIORATES COGNITIVE DEFICITS}, year = {2024}, eissn = {1663-9812} } @article{MTMT:34959307, title = {Predicting Hematoma Expansion and Prognosis in Cerebral Contusions: A Radiomics-Clinical Approach}, url = {https://m2.mtmt.hu/api/publication/34959307}, author = {He, Haoyue and Liu, Jinxin and Li, Chuanming and Guo, Yi and Liang, Kaixin and Du, Jun and Xue, Jun and Liang, Yidan and Chen, Peng and Liu, Liu and Cui, Min and Wang, Jia and Liu, Ye and Tian, Shanshan and Deng, Yongbing}, doi = {10.1089/neu.2023.0410}, journal-iso = {J NEUROTRAUM}, journal = {JOURNAL OF NEUROTRAUMA}, unique-id = {34959307}, issn = {0897-7151}, keywords = {traumatic brain injury; AUTOMATIC SEGMENTATION; radiomics; hematoma expansion; cerebral contusion}, year = {2024}, eissn = {1557-9042}, orcid-numbers = {Liu, Jinxin/0009-0003-8923-2536; Liang, Kaixin/0000-0003-2916-9232} } @article{MTMT:35326392, title = {The promising applications of 3D printing technology in neurotrauma}, url = {https://m2.mtmt.hu/api/publication/35326392}, author = {He, Wenbo and Xu, Chongxi and Wu, Wenbi and Chen, Yuchen and Hou, Jingxuan and Chen, Zhouhaoran and Xu, Jianguo and Gou, Maling and Hu, Yu}, doi = {10.36922/ijb.2311}, journal-iso = {INT J BIOPRINT}, journal = {INTERNATIONAL JOURNAL OF BIOPRINTING}, volume = {10}, unique-id = {35326392}, issn = {2424-7723}, keywords = {traumatic brain injury; spinal cord injury; Peripheral nerve injury; Neurotrauma; Bioprinting; Neural tissue regeneration}, year = {2024}, eissn = {2424-8002}, pages = {61-85} } @article{MTMT:34959290, title = {Characterizing Extreme Phenotypes for Perceived Improvement From Treatment in Persons With Chronic Pain Following Traumatic Brain Injury: A NIDILRR and VA TBI Model Systems Collaborative Project}, url = {https://m2.mtmt.hu/api/publication/34959290}, author = {Hoffman, Jeanne M. and Ketchum, Jessica M. and Agtarap, Stephanie and Dams-O'Connor, Kristen and Hammond, Flora M. and Martin, Aaron M. and Sevigny, Mitch and Walker, William C. and Harrison-Felix, Cynthia and Zafonte, Ross and Nakase-Richardson, Risa}, doi = {10.1097/HTR.0000000000000905}, journal-iso = {J HEAD TRAUMA REHAB}, journal = {JOURNAL OF HEAD TRAUMA REHABILITATION}, volume = {39}, unique-id = {34959290}, issn = {0885-9701}, keywords = {PHENOTYPE; traumatic brain injury; chronic pain; patient reported outcome; perceived improvement}, year = {2024}, eissn = {1550-509X}, pages = {43-55} } @article{MTMT:35326376, title = {Critical thresholds of long-pressure reactivity index and impact of intracranial pressure monitoring methods in traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/35326376}, author = {Hong, Erik and Froese, Logan and Ponten, Emeli and Fletcher-Sandersjoo, Alexander and Tatter, Charles and Hammarlund, Emma and Akerlund, Cecilia A. I. and Tjerkaski, Jonathan and Alpkvist, Peter and Bartek Jr, Jiri and Raj, Rahul and Lindblad, Caroline and Nelson, David W. and Zeiler, Frederick A. and Thelin, Eric P.}, doi = {10.1186/s13054-024-05042-7}, journal-iso = {CRIT CARE}, journal = {CRITICAL CARE}, volume = {28}, unique-id = {35326376}, issn = {1364-8535}, keywords = {traumatic brain injury; Functional outcome; Intracranial Pressure; Pressure reactivity index; Neuro-monitoring}, year = {2024}, eissn = {1466-609X} } @article{MTMT:34474356, title = {Blood biomarkers for traumatic brain injury: A narrative review of current evidence}, url = {https://m2.mtmt.hu/api/publication/34474356}, author = {Hossain, I. and Marklund, N. and Czeiter, Endre and Hutchinson, P. and Büki, András}, doi = {10.1016/j.bas.2023.102735}, journal-iso = {BRAIN SPINE}, journal = {BRAIN AND SPINE}, volume = {4}, unique-id = {34474356}, issn = {2772-5294}, year = {2024}, eissn = {2772-5294}, orcid-numbers = {Czeiter, Endre/0000-0002-9578-6944} } @article{MTMT:34886727, title = {Stakeholder views on cognitive communication assessment and intervention for a person living independently in the community with severe traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/34886727}, author = {Howell, S. and Hoskin, J. and Eaton, D. and Holloway, M. and Varley, R.}, doi = {10.1111/1460-6984.12839}, journal-iso = {INT J LANG COMM DIS}, journal = {INTERNATIONAL JOURNAL OF LANGUAGE & COMMUNICATION DISORDERS}, volume = {59}, unique-id = {34886727}, issn = {1368-2822}, year = {2024}, eissn = {1460-6984}, pages = {483-495} } @article{MTMT:34959272, title = {Causal association between years of schooling and the risk of traumatic brain injury: A two-sample mendelian randomization analysis}, url = {https://m2.mtmt.hu/api/publication/34959272}, author = {Huang, Xinyue and Guo, Xiumei and Gao, Wen and Xiong, Yu and Chen, Chunhui and Zheng, Hanlin and Pan, Zhigang and Wang, Lingxing and Zheng, Shuni and Ke, Chuhan and Stavrinou, Pantelis and Hu, Weipeng and Hong, Kunda and Zheng, Feng}, doi = {10.1016/j.jad.2024.03.045}, journal-iso = {J AFFECT DISORDERS}, journal = {JOURNAL OF AFFECTIVE DISORDERS}, volume = {354}, unique-id = {34959272}, issn = {0165-0327}, keywords = {traumatic brain injury; Mendelian randomization; causal association; years of schooling}, year = {2024}, eissn = {1573-2517}, pages = {483-490} } @article{MTMT:34555882, title = {Long-term survival after primary decompressive craniectomy for severe traumatic brain injury: an observational study from 1 to 17 years}, url = {https://m2.mtmt.hu/api/publication/34555882}, author = {Huang, Yu-Hua and Lee, Tsung-Han}, doi = {10.1007/s10143-024-02289-0}, journal-iso = {NEUROSURG REV}, journal = {NEUROSURGICAL REVIEW}, volume = {47}, unique-id = {34555882}, issn = {0344-5607}, abstract = {Primary decompressive craniectomy (DC) is carried out to prevent intracranial hypertension after removal of mass lesions resulting from traumatic brain injury (TBI). While primary DC can be a life-saving intervention, significant mortality risks persist during the follow-up period. This study was undertaken to investigate the long-term survival rate and ascertain the risk factors of mortality in TBI patients who underwent primary DC. We enrolled 162 head-injured patients undergoing primary DC in this retrospective study. The primary focus was on long-term mortality, which was monitored over a range of 12 to 209 months post-TBI. We compared the clinical parameters of survivors and non-survivors, and used a multivariate logistic regression model to adjust for independent risk factors of long-term mortality. For the TBI patients who survived the initial hospitalization period following surgery, the average duration of follow-up was 106.58 +/- 65.45 months. The recorded long-term survival rate of all patients was 56.2% (91/162). Multivariate logistic regression analysis revealed that age (odds ratio, 95% confidence interval = 1.12, 1.07-1.18; p < 0.01) and the status of basal cisterns (absent versus normal; odds ratio, 95% confidence interval = 9.32, 2.05-42.40; p < 0.01) were the two independent risk factors linked to long-term mortality. In conclusion, this study indicated a survival rate of 56.2% for patients subjected to primary DC for TBI, with at least a one-year follow-up. Key risk factors associated with long-term mortality were advanced age and absent basal cisterns, critical considerations for developing effective TBI management strategies.}, keywords = {AGE; MORTALITY; diagnosis; IMPACT; traumatic brain injury; OUTCOMES; HEAD-INJURY; PREDICTORS; LONG-TERM MORTALITY; Clinical Neurology; INTRACRANIAL-PRESSURE; MASS LESIONS; primary decompressive craniectomy}, year = {2024}, eissn = {1437-2320} } @article{MTMT:35326396, title = {Preclinical Studies on Mechanisms Underlying the Protective Effects of Propranolol in Traumatic Brain Injury: A Systematic Review}, url = {https://m2.mtmt.hu/api/publication/35326396}, author = {Jae, James and Li, Yilong and Sun, Clara and Allan, Alison and Basmaji, John and Chilton, Stephanie and Simsam, Mohammad Hmidan and Kao, Raymond and Owen, Adrian and Parry, Neil and Priestap, Fran and Rochwerg, Bram and Smith, Shane and Turgeon, Alexis F. and Vogt, Kelly and Walser, Eric and Iansavitchene, Alla and Ball, Ian}, doi = {10.1007/s11481-024-10121-1}, journal-iso = {J NEUROIMMUNE PHARM}, journal = {JOURNAL OF NEUROIMMUNE PHARMACOLOGY}, volume = {19}, unique-id = {35326396}, issn = {1557-1890}, keywords = {cognition; traumatic brain injury; PROPRANOLOL; beta-blockade}, year = {2024}, eissn = {1557-1904}, orcid-numbers = {Jae, James/0000-0002-2447-5647; Basmaji, John/0000-0001-9749-1747} } @article{MTMT:34560033, title = {Consensus-Based Development of a Global Registry for Traumatic Brain Injury: Establishment, Protocol, and Implementation}, url = {https://m2.mtmt.hu/api/publication/34560033}, author = {Joannides, A.J. and Korhonen, T.K. and Clark, D. and Gnanakumar, S. and Venturini, S. and Mohan, M. and Bashford, T. and Baticulon, R. and Bhagavatula, I.D. and Esene, I. and Fernández-Méndez, R. and Figaji, A. and Gupta, D. and Khan, T. and Laeke, T. and Martin, M. and Menon, D. and Paiva, W. and Park, K.B. and Pattisapu, J.V. and Rubiano, A.M. and Sekhar, V. and Shabani, H.K. and Sichizya, K. and Solla, D. and Tirsit, A. and Tripathi, M. and Turner, C. and Depreitere, B. and Iaccarino, C. and Lippa, L. and Reisner, A. and Rosseau, G. and Servadei, F. and Trivedi, R.A. and Waran, V. and Kolias, A. and Hutchinson, P.}, doi = {10.1227/neu.0000000000002661}, journal-iso = {NEUROSURGERY}, journal = {NEUROSURGERY}, volume = {94}, unique-id = {34560033}, issn = {0148-396X}, year = {2024}, eissn = {1524-4040}, pages = {278-288} } @article{MTMT:34789714, title = {Transforming research to improve therapies for trauma in the twenty-first century}, url = {https://m2.mtmt.hu/api/publication/34789714}, author = {Juffermans, N.P. and Gözden, T. and Brohi, K. and Davenport, R. and Acker, J.P. and Reade, M.C. and Maegele, M. and Neal, M.D. and Spinella, P.C.}, doi = {10.1186/s13054-024-04805-6}, journal-iso = {CRIT CARE}, journal = {CRITICAL CARE}, volume = {28}, unique-id = {34789714}, issn = {1364-8535}, year = {2024}, eissn = {1466-609X} } @article{MTMT:34959289, title = {Recent insights from non-mammalian models of brain injuries: an emerging literature}, url = {https://m2.mtmt.hu/api/publication/34959289}, author = {Katchur, Nicole J. and Notterman, Daniel A.}, doi = {10.3389/fneur.2024.1378620}, journal-iso = {FRONT NEUR}, journal = {FRONTIERS IN NEUROLOGY}, volume = {15}, unique-id = {34959289}, issn = {1664-2295}, keywords = {traumatic brain injury; neurodegeneration; tauopathy; non-mammalian models; repetitive brain injury}, year = {2024}, eissn = {1664-2295} } @article{MTMT:35326389, title = {Advances in Neurorehabilitation: Strategies and Outcomes for Traumatic Brain Injury Recovery}, url = {https://m2.mtmt.hu/api/publication/35326389}, author = {Kaurani, Purvi and de Marchi Apolaro, Ana Vitoria Moreira and Kunchala, Keerthi and Maini, Shriya and Rges, Huda A. F. and Isaac, Ashley and Lakkimsetti, Mohit and Raake, Mohammed and Nazir, Zahra}, doi = {10.7759/cureus.62242}, journal-iso = {CUREUS}, journal = {CUREUS}, volume = {16}, unique-id = {35326389}, keywords = {traumatic brain injury; concussion; AXONAL INJURY; virtual reality simulation; neurorehabilitation neurorehab}, year = {2024}, eissn = {2168-8184} } @article{MTMT:34933460, title = {The Australian Traumatic Brain Injury Initiative: Systematic Review of the Effect of Acute Interventions on Outcome for People With Moderate-Severe Traumatic Brain Injury}, url = {https://m2.mtmt.hu/api/publication/34933460}, author = {Keeves, Jemma and Gadowski, Adelle and McKimmie, Ancelin and Bagg, Matthew K. and Antonic-Baker, Ana and Hicks, Amelia J. and Clarke, Nyssa and Brown, Alastair and McNamara, Rob and Reeder, Sandy and Roman, Cristina and Jeffcote, Toby and Romero, Lorena and Hill, Regina and Ponsford, Jennie L. and Lannin, Natasha A. and O'Brien, Terence J. and Cameron, Peter A. and Rushworth, Nick and Fitzgerald, Melinda and Gabbe, Belinda J. and Cooper, D. Jamie}, doi = {10.1089/neu.2023.0465}, journal-iso = {J NEUROTRAUM}, journal = {JOURNAL OF NEUROTRAUMA}, unique-id = {34933460}, issn = {0897-7151}, keywords = {Brain Injuries, Traumatic; common data elements; Outcome Assessment, Health Care; Systematic review [Publication type]; emergency medical services, critical care, early medical intervention}, year = {2024}, eissn = {1557-9042}, orcid-numbers = {Romero, Lorena/0000-0001-9884-5463} } @article{MTMT:34789554, title = {Preliminary Evaluation of the Scandinavian Guidelines for Initial Management of Minimal, Mild, and Moderate Head Injuries with Glial Fibrillary Acidic Protein}, url = {https://m2.mtmt.hu/api/publication/34789554}, author = {Keski-Pukkila, Mira and Karr, Justin E. and Posti, Jussi P. and Berghem, Ksenia and Kotilainen, Anna-Kerttu and Blennow, Kaj and Zetterberg, Henrik and Iverson, Grant L. and Luoto, Teemu M.}, doi = {10.1089/neur.2023.0077}, journal-iso = {NEUROTRAUMA REP}, journal = {NEUROTRAUMA REPORTS}, volume = {5}, unique-id = {34789554}, year = {2024}, eissn = {2689-288X}, pages = {50-60} } @article{MTMT:35326391, title = {Factors affecting severity and prognosis of traumatic brain injury among Bangladeshi patients: An institution based cross-sectional study}, url = {https://m2.mtmt.hu/api/publication/35326391}, author = {Khan, Sabrin I. and Karim, Reatul and Khan, Shahriar I. and Chowdhury, Mohiuddin A. K. and Shill, Manik C. and Pasha, Faisal M. and Shohag, Md. H. and Khan, Ferdous and Islam, Md. A. and Mitul, Ariful I. and Ahmad, Reaz and Hossain, Md. S. and Reza, Hasan M.}, doi = {10.1080/15389588.2024.2363470}, journal-iso = {TRAFFIC INJ PREV}, journal = {TRAFFIC INJURY PREVENTION}, unique-id = {35326391}, issn = {1538-9588}, keywords = {Prognosis; traumatic brain injury; Glasgow coma scale; Road Traffic Accident; Glasgow outcome score}, year = {2024}, eissn = {1538-957X} } @article{MTMT:34625110, title = {Treatment with Rapamycin in Animal Models of Traumatic Brain Injuries; a Systematic Review and Meta-Analysis}, url = {https://m2.mtmt.hu/api/publication/34625110}, author = {Kiah, Mohammad and Azimi, Amir and Hajisoltani, Razieh and Yousefifard, Mahmoud}, doi = {10.22037/aaem.v12i1.2150}, journal-iso = {ARCH ACAD EMERG MED}, journal = {ARCHIVES OF ACADEMIC EMERGENCY MEDICINE}, volume = {12}, unique-id = {34625110}, keywords = {MODELS; animal; Meta-analysis; Brain Injuries; systematic review; traumatic}, year = {2024}, eissn = {2645-4904} } @article{MTMT:35167358, title = {Clinical Insights and Future Directions in Hypothermia for Severe Traumatic Brain Injury: A Narrative Review}, url = {https://m2.mtmt.hu/api/publication/35167358}, author = {Kobata, H.}, doi = {10.3390/jcm13144221}, journal-iso = {J CLIN MED}, journal = {JOURNAL OF CLINICAL MEDICINE}, volume = {13}, unique-id = {35167358}, year = {2024}, eissn = {2077-0383} } @article{MTMT:35234868, title = {Outlier Analysis for Acute Blood Biomarkers of Moderate and Severe Traumatic Brain Injury}, url = {https://m2.mtmt.hu/api/publication/35234868}, author = {Korhonen, O. and Mononen, M. and Mohammadian, M. and Tenovuo, O. and Blennow, K. and Hossain, I. and Hutchinson, P. and Maanpää, H.-R. and Menon, D.K. and Newcombe, V.F. and Sanchez, J.-C. and Takala, R.S.K. and Tallus, J. and van, Gils M. and Zetterberg, H. and Posti, J.P.}, doi = {10.1089/neu.2023.0120}, journal-iso = {J NEUROTRAUM}, journal = {JOURNAL OF NEUROTRAUMA}, volume = {41}, unique-id = {35234868}, issn = {0897-7151}, year = {2024}, eissn = {1557-9042}, pages = {91-105} } @article{MTMT:35326358, title = {Diagnostic Accuracy of SPECT for Mild Traumatic Brain Injury}, url = {https://m2.mtmt.hu/api/publication/35326358}, author = {Koziarz, Alex and Koziarz, Frank and Shen, Rui and Gopee-Ramanan, Prasaanthan and Black, Sandra E. and Worsley, Daniel and Chan, Ian Y. M. and Streiner, David L. and Zukotynski, Katherine A.}, doi = {10.1097/RLU.0000000000005328}, journal-iso = {CLIN NUCL MED}, journal = {CLINICAL NUCLEAR MEDICINE}, volume = {49}, unique-id = {35326358}, issn = {0363-9762}, keywords = {traumatic brain injury; SPECT; concussion}, year = {2024}, eissn = {1536-0229}, pages = {938-947} } @article{MTMT:34959282, title = {Reference Values for the German Version of the Quality of Life after Brain Injury in Children and Adolescents (QOLIBRI-KID/ADO) from a General Population Sample}, url = {https://m2.mtmt.hu/api/publication/34959282}, author = {Krol, Leonie and Hagmayer, York and Steinbuechel, Nicole von and Cunitz, Katrin and Buchheim, Anna and Koerte, Inga K. and Zeldovich, Marina}, doi = {10.3390/jpm14040336}, journal-iso = {J PERS MED}, journal = {JOURNAL OF PERSONALIZED MEDICINE}, volume = {14}, unique-id = {34959282}, keywords = {Reference Values; Children and adolescents; traumatic brain injury; health-related quality of life; General population; patient-reported outcome measure (PROM)}, year = {2024}, eissn = {2075-4426}, orcid-numbers = {Cunitz, Katrin/0000-0001-5530-8190; Buchheim, Anna/0000-0002-1339-5246; Zeldovich, Marina/0000-0003-0172-9904} } @article{MTMT:34959257, title = {Impaired autophagic flux in the human brain after traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/34959257}, author = {Lang, Jiadong and Sun, Boyu and Feng, Shiyao and Sun, Guozhu}, doi = {10.1097/WNR.0000000000002020}, journal-iso = {NEUROREPORT}, journal = {NEUROREPORT}, volume = {35}, unique-id = {34959257}, issn = {0959-4965}, keywords = {traumatic brain injury; Cathepsin D; Autophagic flux; autophagic substrate sequestosome 1; lipidated microtubule-associated protein light-chain 3}, year = {2024}, eissn = {1473-558X}, pages = {387-398} } @article{MTMT:35326361, title = {Cellular senescence: A novel therapeutic target for central nervous system diseases}, url = {https://m2.mtmt.hu/api/publication/35326361}, author = {Lei, Shuang-Yin and Qu, Yang and Yang, Yu-Qian and Liu, Jia-Cheng and Zhang, Yi-Fei and Zhou, Sheng-Yu and He, Qian-Yan and Jin, Hang and Yang, Yi and Guo, Zhen-Ni}, doi = {10.1016/j.biopha.2024.117311}, journal-iso = {BIOMED PHARMACOTHER}, journal = {BIOMEDICINE & PHARMACOTHERAPY}, volume = {179}, unique-id = {35326361}, issn = {0753-3322}, keywords = {neurodegenerative diseases; Central Nervous System Diseases; senescence; cellular senescence; Senolytics}, year = {2024}, eissn = {1950-6007} } @article{MTMT:35234251, title = {Prevalence of tinnitus following non-blast related traumatic brain injury: a systematic review of literature}, url = {https://m2.mtmt.hu/api/publication/35234251}, author = {Le, M. and Šarkić, B. and Anderson, R.}, doi = {10.1080/02699052.2024.2353798}, journal-iso = {BRAIN INJURY}, journal = {BRAIN INJURY}, volume = {38}, unique-id = {35234251}, issn = {0269-9052}, year = {2024}, eissn = {1362-301X}, pages = {859-868} } @article{MTMT:34560063, title = {The Use of Biofluid Markers to Evaluate the Consequences of Sport-Related Subconcussive Head Impact Exposure: A Scoping Review}, url = {https://m2.mtmt.hu/api/publication/34560063}, author = {Lember, L.-M. and Ntikas, M. and Mondello, S. and Wilson, L. and Di, Virgilio T.G. and Hunter, A.M. and Kobeissy, F. and Mechref, Y. and Donaldson, D.I. and Ietswaart, M.}, doi = {10.1186/s40798-023-00665-6}, journal-iso = {SPORT MED-OPEN}, journal = {SPORTS MEDICINE-OPEN}, volume = {10}, unique-id = {34560063}, issn = {2199-1170}, year = {2024}, eissn = {2198-9761} } @article{MTMT:35326398, title = {Spatial lipidomics maps brain alterations associated with mild traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/35326398}, author = {Leontyev, Dmitry and Pulliam, Alexis N. and Ma, Xin and Gaul, David A. and LaPlaca, Michelle C. and Fernandez, Facundo M.}, doi = {10.3389/fchem.2024.1394064}, journal-iso = {FRONT CHEM}, journal = {FRONTIERS IN CHEMISTRY}, volume = {12}, unique-id = {35326398}, issn = {2296-2646}, keywords = {Mild traumatic brain injury; Controlled cortical impact; Mass spectrometry imaging; Fourier transform ion cyclotron resonance; spatial lipidomics}, year = {2024}, eissn = {2296-2646} } @article{MTMT:34959263, title = {Differences in clinical outcomes and resource utilization in pediatric traumatic brain injury between countries of different sociodemographic indices}, url = {https://m2.mtmt.hu/api/publication/34959263}, author = {Liang, Keith Wei Han and Lee, Jan Hau and Qadri, Syeda K. and Nadarajan, Janani and Caporal, Paula and Roa, Juan D. and Gonzalez-Dambrauskas, Sebastian and Abbas, Qalab and Kazzaz, Yasser and Chong, Shu-Ling}, doi = {10.3171/2024.1.PEDS23306}, journal-iso = {J NEUROS-PEDIATR}, journal = {JOURNAL OF NEUROSURGERY - PEDIATRICS}, volume = {33}, unique-id = {34959263}, issn = {1933-0707}, keywords = {Child; Asia; traumatic brain injury; OUTCOMES; Latin America; global surgery; sociodemographic status}, year = {2024}, eissn = {1933-0715}, pages = {461-468} } @article{MTMT:34959258, title = {Occupational therapy scope of practice in the rehabilitation of adults experiencing persistent post-concussion symptoms following traumatic brain injury: a scoping review protocol}, url = {https://m2.mtmt.hu/api/publication/34959258}, author = {Licciardi, Lisa and Olver, John and Lalor, Aislinn and Callaway, Libby}, doi = {10.11124/JBIES-23-00176}, journal-iso = {JBI EVID SYNTH}, journal = {JBI EVIDENCE SYNTHESIS}, volume = {22}, unique-id = {34959258}, keywords = {RECOVERY; Mild traumatic brain injury; concussion; Scope of practice; allied health}, year = {2024}, eissn = {2689-8381}, pages = {727-736}, orcid-numbers = {Licciardi, Lisa/0000-0001-7707-5762; Olver, John/0000-0001-7069-1191; Lalor, Aislinn/0000-0002-9772-5272; Callaway, Libby/0000-0002-3127-6312} } @article{MTMT:35326372, title = {Risk factors and outcomes associated with systolic dysfunction following traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/35326372}, author = {Li, Jungen and Miao, Yuzhu and Zhang, Guoxing and Xu, Xiaowen and Guo, Yanxia and Zhou, Bingyuan and Jiang, Tingbo and Lu, Shiqi}, doi = {10.1097/MD.0000000000038891}, journal-iso = {MEDICINE}, journal = {MEDICINE}, volume = {103}, unique-id = {35326372}, issn = {0025-7974}, keywords = {Prognosis; Heart Rate; Echocardiography; systolic blood pressure; traumatic brain injury; systolic dysfunction; hypersensitive cardiac troponin T}, year = {2024}, eissn = {1536-5964} } @article{MTMT:34899461, title = {Intervention of CXCL5 attenuated neuroinflammation and promoted neurological recovery after traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/34899461}, author = {Li, L. and Zhou, J. and Han, L. and Guo, C. and Ma, S. and Ge, S. and Qu, Y.}, doi = {10.1097/WNR.0000000000002032}, journal-iso = {NEUROREPORT}, journal = {NEUROREPORT}, volume = {35}, unique-id = {34899461}, issn = {0959-4965}, abstract = {Neuroinflammation after traumatic brain injury (TBI) exhibits a strong correlation with neurological impairment, which is a crucial target for improving the prognosis of TBI patients. The involvement of CXCL5/CXCR2 signaling in the regulation of neuroinflammation in brain injury models has been documented. Therefore, the effects of CXCL5 on post-TBI neuroinflammation and its potential mechanisms need to be explored. Following TBI, C57BL/6 mice were administered intraperitoneal injections of a CXCL5 neutralizing antibody (Nab-CXCL5) (5 mg/kg, 2 times/day). Subsequently, the effects on neuroinflammation, nerve injury, and neurological function were assessed. Nab-CXCL5 significantly reduced the release of inflammatory factors, inhibited the formation of inflammatory microglia and astrocytes, and reduced the infiltration of peripheral immune cells in TBI mice. Additionally, this intervention led to a reduction in neuronal impairment and facilitated the restoration of sensorimotor abilities, as well as improvements in learning and memory functions. Peripheral administration of the Nab-CXCL5 to TBI mice could suppress neuroinflammation, reduce neurological damage, and improve neurological function. Our data suggest that neutralizing antibodies against CXCL5 (Nab-CXCL5) may be a promising agent for treating TBI. © 2024 Lippincott Williams and Wilkins. All rights reserved.}, keywords = {Animals; Male; Male; metabolism; MICE; ARTICLE; MOUSE; immunology; animal; Mice, Inbred C57BL; physiology; controlled study; nonhuman; animal tissue; animal model; animal experiment; enzyme linked immunosorbent assay; cell infiltration; drug effect; unclassified drug; interleukin 6; interleukin 10; Tumor Necrosis Factor; immunocompetent cell; neutralizing antibody; neutralizing antibody; leukocyte; traumatic brain injury; traumatic brain injury; traumatic brain injury; neutrophil chemotaxis; antiinflammatory agent; neuroinflammation; microglia; microglia; microglia; motor performance; C57BL mouse; interleukin 1beta; inducible nitric oxide synthase; Recovery of Function; ASTROCYTE; convalescence; nervous system inflammation; nervous system inflammation; nerve injury; REACTIVE ASTROCYTES; Antibodies, Neutralizing; TUNEL assay; Brain Injuries, Traumatic; protein expression level; nissl staining; immunofluorescence assay; lesion volume; epithelial derived neutrophil activating factor 78; CXCL5; swimming speed; Chemokine CXCL5; neuroinflammatory diseases; cxcl5 neutralizing antibody; Cxcl5 protein, mouse}, year = {2024}, eissn = {1473-558X}, pages = {549-557} } @article{MTMT:35326362, title = {Perspectives of healthcare providers on withdrawal of life-sustaining treatment and advanced directives for unresponsive wakefulness syndrome in China}, url = {https://m2.mtmt.hu/api/publication/35326362}, author = {Li, Meiqi and Dai, Siyu and Wang, Le and Di, Haibo}, doi = {10.3389/fneur.2024.1358747}, journal-iso = {FRONT NEUR}, journal = {FRONTIERS IN NEUROLOGY}, volume = {15}, unique-id = {35326362}, issn = {1664-2295}, keywords = {ETHICS; Disorders of Consciousness; Unresponsive wakefulness syndrome; withdrawal of life-sustaining treatment; advanced directives}, year = {2024}, eissn = {1664-2295} } @article{MTMT:35234534, title = {Empowering Support for Family Members of Brain Injury Patients in the Acute Phase of Hospital Care: A Mixed-Methods Systematic Review}, url = {https://m2.mtmt.hu/api/publication/35234534}, author = {Lindlöf, J. and Turunen, H. and Välimäki, T. and Huhtakangas, J. and Verhaeghe, S. and Coco, K.}, doi = {10.1177/10748407231171933}, journal-iso = {J FAM NURS}, journal = {JOURNAL OF FAMILY NURSING}, volume = {30}, unique-id = {35234534}, issn = {1074-8407}, year = {2024}, eissn = {1552-549X}, pages = {50-67} } @article{MTMT:35326370, title = {Annexin-A1 tripeptide enhances functional recovery and mitigates brain damage in traumatic brain injury by inhibiting neuroinflammation and preventing ANXA1 nuclear translocation in mice}, url = {https://m2.mtmt.hu/api/publication/35326370}, author = {Lin, Kai and Hou, Yuejiao and Li, Ruxin and Fan, Fengyan and Hao, Yinan and Wang, Yuan and Huang, Yue and Li, Peng and Zhu, Lingling and Huang, Xin and Zhao, Yong-Qi}, doi = {10.1007/s11011-024-01404-w}, journal-iso = {METAB BRAIN DIS}, journal = {METABOLIC BRAIN DISEASE}, unique-id = {35326370}, issn = {0885-7490}, keywords = {traumatic brain injury; neuroinflammation; Neuronal cell death; ANXA1sp}, year = {2024}, eissn = {1573-7365} } @article{MTMT:35326354, title = {Combined Phloretin and Human Platelet-rich Plasma Effectively Preserved Integrities of Brain Structure and Neurological Function in Rat after Traumatic Brain Damage}, url = {https://m2.mtmt.hu/api/publication/35326354}, author = {Lin, Kun-Chen and Chen, Kuan-Hung and Shao, Pei-Lin and Chai, Han-Tan and Sung, Pei-Hsun and Chiang, John Y. and Ko, Sheung-Fat and Yip, Hon-Kan}, doi = {10.2174/0118761429316684240816062458}, journal-iso = {CURR MOL PHARMACOL}, journal = {CURRENT MOLECULAR PHARMACOLOGY}, unique-id = {35326354}, issn = {1874-4672}, keywords = {Inflammation; MRI; Platelet-rich plasma; phloretin; Acute traumatic brain injury; BHV}, year = {2024}, eissn = {1874-4702}, orcid-numbers = {Yip, Hon-Kan/0000-0002-6305-5717} } @article{MTMT:34959271, title = {Armcx1 Reduces Neurological Damage Via a Mitochondrial Transport Pathway Involving Miro1 After Traumatic Brain Injury}, url = {https://m2.mtmt.hu/api/publication/34959271}, author = {Li, Qiuying and Ni, Haibo and Rui, Qin and Ding, Jiasheng and Kong, Xianghu and Kan, Xugang and Gao, Rong and Shen, Hongbo}, doi = {10.1016/j.neuroscience.2024.03.009}, journal-iso = {NEUROSCIENCE}, journal = {NEUROSCIENCE}, volume = {545}, unique-id = {34959271}, issn = {0306-4522}, keywords = {APOPTOSIS; Mitochondria; traumatic brain injury; Miro1; Armcx1}, year = {2024}, eissn = {1873-7544}, pages = {111-124} } @article{MTMT:34959292, title = {Cognitive impairment in Chinese traumatic brain injury patients: from challenge to future perspectives}, url = {https://m2.mtmt.hu/api/publication/34959292}, author = {Liu, Tao and Yu, Shaohui and Liu, Mingqi and Zhao, Zhihao and Yuan, Jiangyuan and Sha, Zhuang and Liu, Xuanhui and Qian, Yu and Nie, Meng and Jiang, Rongcai}, doi = {10.3389/fnins.2024.1361832}, journal-iso = {FRONT NEUROSCI-SWITZ}, journal = {FRONTIERS IN NEUROSCIENCE}, volume = {18}, unique-id = {34959292}, issn = {1662-4548}, keywords = {DYSFUNCTION; Risk Factors; EPIDEMIOLOGY; traumatic brain injury; COGNITIVE IMPAIRMENT; OPPORTUNITIES; CHALLENGES}, year = {2024}, eissn = {1662-453X}, orcid-numbers = {Liu, Tao/0000-0002-0506-3356; Sha, Zhuang/0000-0002-8110-1481} } @article{MTMT:34560232, title = {Mapping general anesthesia states based on electro-encephalogram transition phases}, url = {https://m2.mtmt.hu/api/publication/34560232}, author = {Loison, V. and Voskobiynyk, Y. and Lindquist, B. and Necula, D. and Longrois, D. and Paz, J. and Holcman, D.}, doi = {10.1016/j.neuroimage.2023.120498}, journal-iso = {NEUROIMAGE}, journal = {NEUROIMAGE}, volume = {285}, unique-id = {34560232}, issn = {1053-8119}, year = {2024}, eissn = {1095-9572} } @article{MTMT:34625108, title = {Design recommendations for XR-based motor rehabilitation exergames at home}, url = {https://m2.mtmt.hu/api/publication/34625108}, author = {Lorenz, Emanuel A. and Stoen, Andreas Braten and Fridheim, Magnus Lie and Alsos, Ole Andreas}, doi = {10.3389/frvir.2024.1340072}, journal-iso = {FRONT VIRTUAL REAL}, journal = {FRONTIERS IN VIRTUAL REALITY}, volume = {5}, unique-id = {34625108}, keywords = {Game design; virtual reality (VR); Co-design; Design recommendations; motor rehabilitation; Exergame; Extended Reality (XR); acquired brain injuries (ABI)}, year = {2024}, eissn = {2673-4192} } @article{MTMT:34959262, title = {Enhancing T1 signal of normal-appearing white matter with divided subtracted inversion recovery: A pilot study in mild traumatic brain injury}, url = {https://m2.mtmt.hu/api/publication/34959262}, author = {Losa, Letizia and Peruzzo, Denis and Galbiati, Sara and Locatelli, Federica and Agarwal, Nivedita}, doi = {10.1002/nbm.5175}, journal-iso = {NMR BIOMED}, journal = {NMR IN BIOMEDICINE}, unique-id = {34959262}, issn = {0952-3480}, keywords = {Mild traumatic brain injury; normal-appearing white matter; T1 mapping; White matter hyperintensities; neurofluids; divided subtracted inversion recovery; microstructural injury}, year = {2024}, eissn = {1099-1492}, orcid-numbers = {Losa, Letizia/0000-0002-6044-9999; Peruzzo, Denis/0000-0002-9480-379X} } @article{MTMT:35231262, title = {Emergency Department Risk Factors for Post-Concussion Syndrome After Mild Traumatic Brain Injury: A Systematic Review}, url = {https://m2.mtmt.hu/api/publication/35231262}, author = {Lubbers, V.F. and van, den Hoven D.J. and van, der Naalt J. and Jellema, K. and van, den Brand C. and Backus, B.}, doi = {10.1089/neu.2023.0302}, journal-iso = {J NEUROTRAUM}, journal = {JOURNAL OF NEUROTRAUMA}, volume = {41}, unique-id = {35231262}, issn = {0897-7151}, year = {2024}, eissn = {1557-9042}, pages = {1253-1270} } @article{MTMT:34555601, title = {Classification and Characterization of Traumatic Brain Injuries in the Northern Region of Sweden}, url = {https://m2.mtmt.hu/api/publication/34555601}, author = {Magnusson, Beatrice M. and Koskinen, Lars-Owe D.}, doi = {10.3390/jcm13010008}, journal-iso = {J CLIN MED}, journal = {JOURNAL OF CLINICAL MEDICINE}, volume = {13}, unique-id = {34555601}, abstract = {Background: Traumatic brain injury (TBI) is a common cause of death and disability, the incidence of which in northern Sweden is not fully investigated. This study classifies and characterize epidemiological and demographic features of TBIs in a defined population in Umea county, Sweden. Specifically, to evaluate frequencies of (1) intracranial lesions detected with computed tomography (CT), (2) need for emergency intervention, and (3) hospital admission, in minimal, mild, moderate, and severe TBI, respectively. Methods: The data were gathered from 4057 TBI patients visiting our emergency room (ER) during a two-year period (2015-2016), of whom 56% were men and approximately 95% had minimal TBIs (Glasgow Coma Scale (GCS), score 15). Results: Of all injuries, 97.8% were mild (GCS 14-15), 1.7% were moderate (GCS 9-13), and 0.5% were severe (GCS < 9). CT scans were performed on 46% of the patients, with 28% being hospitalized. A high annual TBI incidence of 1350 cases per 100,000 citizens was found. The mortality rate was 0.5% with the majority as expected in the elderly group (>80 years). Conclusions: Minimal TBIs were not as mild as previously reported, with a relatively high frequency of abnormal CT findings and a high mortality rate. No emergency intervention was required in patients in the GCS 13-15 group with normal CT scans. These findings have implications for clinical practice in the ER with the suggestion to include biomarkers to reduce unnecessary CT scans.}, keywords = {MORTALITY; PREVENTION; MANAGEMENT; EPIDEMIOLOGY; traumatic brain injury; Glasgow coma scale; outcome; HEAD-INJURY; intervention; Demographics; ADMISSION; CT scan; CENTER-TBI; epidemiological}, year = {2024}, eissn = {2077-0383}, orcid-numbers = {Koskinen, Lars-Owe D./0000-0003-3528-8502} } @article{MTMT:35326387, title = {Would You Rather: Quantifying Traumatic Brain Injury Survivor Perceptions of Functional Status Through Their Surrogates}, url = {https://m2.mtmt.hu/api/publication/35326387}, author = {Maiga, Amelia W. and Cook, Madison R. and Nordness, Mina F. and Gao, Yue and Rakhit, Shayan and Rivera, Erika L. and Harrell, Frank E. and Patel, Mayur B.}, doi = {10.1097/SLA.0000000000006274}, journal-iso = {ANN SURG}, journal = {ANNALS OF SURGERY}, volume = {280}, unique-id = {35326387}, issn = {0003-4932}, keywords = {Quality of Life; traumatic brain injury; health utilities; Glasgow Outcome Scale-Extended}, year = {2024}, eissn = {1528-1140}, pages = {144-149} }