@article{MTMT:34538788,
	title = {Circulating miRNAs and Preeclampsia: From Implantation to Epigenetics},
	url = {https://m2.mtmt.hu/api/publication/34538788},
	author = {Giannubilo, Stefano Raffaele and Cecati, Monia and Marzioni, Daniela and Ciavattini, Andrea},
	doi = {10.3390/ijms25031418},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {25},
	unique-id = {34538788},
	issn = {1661-6596},
	abstract = {In this review, we comprehensively present the literature on circulating microRNAs (miRNAs) associated with preeclampsia, a pregnancy-specific disease considered the primary reason for maternal and fetal mortality and morbidity. miRNAs are single-stranded non-coding RNAs, 20–24 nt long, which control mRNA expression. Changes in miRNA expression can induce a variation in the relative mRNA level and influence cellular homeostasis, and the strong presence of miRNAs in all body fluids has made them useful biomarkers of several diseases. Preeclampsia is a multifactorial disease, but the etiopathogenesis remains unclear. The functions of trophoblasts, including differentiation, proliferation, migration, invasion and apoptosis, are essential for a successful pregnancy. During the early stages of placental development, trophoblasts are strictly regulated by several molecular pathways; however, an imbalance in these molecular pathways can lead to severe placental lesions and pregnancy complications. We then discuss the role of miRNAs in trophoblast invasion and in the pathogenesis, diagnosis and prediction of preeclampsia. We also discuss the potential role of miRNAs from an epigenetic perspective with possible future therapeutic implications.},
	year = {2024},
	eissn = {1422-0067},
	orcid-numbers = {Giannubilo, Stefano Raffaele/0000-0002-9427-1391; Marzioni, Daniela/0000-0002-2267-0270}
}

@article{MTMT:34568040,
	title = {Maternal–Infant Factors in Relation to Extracellular Vesicle and Particle miRNA in Prenatal Plasma and in Postpartum Human Milk},
	url = {https://m2.mtmt.hu/api/publication/34568040},
	author = {Muse, Meghan E. and Armstrong, David A. and Hoen, Anne G. and Gilbert-Diamond, Diane and Gui, Jiang and Palys, Thomas J. and Kolling, Frederick W. and Christensen, Brock C. and Karagas, Margaret R. and Howe, Caitlin G.},
	doi = {10.3390/ijms25031538},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {25},
	unique-id = {34568040},
	issn = {1661-6596},
	abstract = {MicroRNAs (miRNA) in extracellular vesicles and particles (EVPs) in maternal circulation during pregnancy and in human milk postpartum are hypothesized to facilitate maternal–offspring communication via epigenetic regulation. However, factors influencing maternal EVP miRNA profiles during these two critical developmental windows remain largely unknown. In a pilot study of 54 mother–child dyads in the New Hampshire Birth Cohort Study, we profiled 798 EVP miRNAs, using the NanoString nCounter platform, in paired maternal second-trimester plasma and mature (6-week) milk samples. In adjusted models, total EVP miRNA counts were lower for plasma samples collected in the afternoon compared with the morning (p = 0.024). Infant age at sample collection was inversely associated with total miRNA counts in human milk EVPs (p = 0.040). Milk EVP miRNA counts were also lower among participants who were multiparous after delivery (p = 0.047), had a pre-pregnancy BMI > 25 kg/m2 (p = 0.037), or delivered their baby via cesarean section (p = 0.021). In post hoc analyses, we also identified 22 specific EVP miRNA that were lower among participants who delivered their baby via cesarean section (Q < 0.05). Target genes of delivery mode-associated miRNAs were over-represented in pathways related to satiety signaling in infants (e.g., CCKR signaling) and mammary gland development and lactation (e.g., FGF signaling, EGF receptor signaling). In conclusion, we identified several key factors that may influence maternal EVP miRNA composition during two critical developmental windows, which should be considered in future studies investigating EVP miRNA roles in maternal and child health.},
	year = {2024},
	eissn = {1422-0067},
	orcid-numbers = {Muse, Meghan E./0000-0002-4775-2133; Armstrong, David A./0000-0003-1748-2520; Gilbert-Diamond, Diane/0000-0003-3560-7171; Howe, Caitlin G./0000-0002-4935-9298}
}

@article{MTMT:34778022,
	title = {The functions and applications of extracellular vesicles miRNAs in adverse pregnancy},
	url = {https://m2.mtmt.hu/api/publication/34778022},
	author = {Song, Huichen and Ma, Lina and Sun, Benben and Shi, Huanhuan and Zhang, Yujing},
	doi = {10.55092/exrna20240005},
	journal-iso = {EXRNA},
	journal = {EXRNA},
	volume = {6},
	unique-id = {34778022},
	year = {2024},
	eissn = {2398-0060}
}

@article{MTMT:34722095,
	title = {The pharmaco-epigenetics of hypertension: a focus on microRNA},
	url = {https://m2.mtmt.hu/api/publication/34722095},
	author = {Yaacoub, Serge and Boudaka, Ammar and AlKhatib, Ali and Pintus, Gianfranco and Sahebkar, Amirhossein and Kobeissy, Firas and Eid, Ali H.},
	doi = {10.1007/s11010-024-04947-9},
	journal-iso = {MOL CELL BIOCHEM},
	journal = {MOLECULAR AND CELLULAR BIOCHEMISTRY},
	volume = {in press},
	unique-id = {34722095},
	issn = {0300-8177},
	abstract = {Hypertension is a major harbinger of cardiovascular morbidity and mortality. It predisposes to higher rates of myocardial infarction, chronic kidney failure, stroke, and heart failure than most other risk factors. By 2025, the prevalence of hypertension is projected to reach 1.5 billion people. The pathophysiology of this disease is multifaceted, as it involves nitric oxide and endothelin dysregulation, reactive oxygen species, vascular smooth muscle proliferation, and vessel wall calcification, among others. With the advent of new biomolecular techniques, various studies have elucidated a gaping hole in the etiology and mechanisms of hypertension. Indeed, epigenetics, DNA methylation, histone modification, and microRNA-mediated translational silencing appear to play crucial roles in altering the molecular phenotype into a hypertensive profile. Here, we critically review the experimentally determined associations between microRNA (miRNA) molecules and hypertension pharmacotherapy. Particular attention is given to the epigenetic mechanisms underlying the physiological responses to antihypertensive drugs like candesartan, and other relevant drugs like clopidogrel, aspirin, and statins among others. Furthermore, how miRNA affects the pharmaco-epigenetics of hypertension is especially highlighted.},
	year = {2024},
	eissn = {1573-4919},
	orcid-numbers = {Eid, Ali H./0000-0003-3004-5675}
}

@article{MTMT:34806786,
	title = {Emerging role of exosomes as a liquid biopsy tool for diagnosis, prognosis & monitoring treatment response of communicable & non-communicable diseases},
	url = {https://m2.mtmt.hu/api/publication/34806786},
	author = {Yadav, Rajbala and Singh, AjayVir and Kushwaha, Shweta and Chauhan, DevendraSingh},
	doi = {10.4103/ijmr.ijmr_2344_22},
	journal-iso = {INDIAN J MED RES},
	journal = {INDIAN JOURNAL OF MEDICAL RESEARCH},
	volume = {159},
	unique-id = {34806786},
	issn = {0971-5916},
	year = {2024},
	eissn = {0971-5916}
}

@article{MTMT:33661426,
	title = {Associations of maternal and placental extracellular vesicle miRNA with preeclampsia},
	url = {https://m2.mtmt.hu/api/publication/33661426},
	author = {Aharon, Anat and Rebibo-Sabbah, Annie and Ahmad, Rawan Sayed and Dangot, Ayelet and Bar-Lev, Tali Hana and Brenner, Benjamin and Cohen, Adi Halberthal and David, Chen Ben and Weiner, Zeev and Solt, Ido},
	doi = {10.3389/fcell.2023.1080419},
	journal-iso = {FRONT CELL DEV BIOL},
	journal = {FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY},
	volume = {11},
	unique-id = {33661426},
	issn = {2296-634X},
	abstract = {Introduction: Gestational vascular complications (GVCs), including gestational hypertension and preeclampsia, are leading causes of maternal morbidity and mortality. Elevated levels of extracellular vesicles (EVs), in GVC have been linked to vascular injury. This study aims to characterize placental and circulating EV miRNA in GVCs, and explores the involvement of EV-miRNA in GVC, and whether they may be used to distinguish between placental and maternal pathologies.},
	year = {2023},
	eissn = {2296-634X}
}

@article{MTMT:34104586,
	title = {From Molecules to Imaging: Assessment of Placental Hypoxia Biomarkers in Placental Insufficiency Syndromes},
	url = {https://m2.mtmt.hu/api/publication/34104586},
	author = {Al Darwish, Fatimah M. and Meijerink, Lotte and Coolen, Bram F. and Strijkers, Gustav J. and Bekker, Mireille and Lely, Titia and Terstappen, Fieke},
	doi = {10.3390/cells12162080},
	journal-iso = {CELLS-BASEL},
	journal = {CELLS},
	volume = {12},
	unique-id = {34104586},
	abstract = {Placental hypoxia poses significant risks to both the developing fetus and the mother during pregnancy, underscoring the importance of early detection and monitoring. Effectively identifying placental hypoxia and evaluating the deterioration in placental function requires reliable biomarkers. Molecular biomarkers in placental tissue can only be determined post-delivery and while maternal blood biomarkers can be measured over time, they can merely serve as proxies for placental function. Therefore, there is an increasing demand for non-invasive imaging techniques capable of directly assessing the placental condition over time. Recent advancements in imaging technologies, including photoacoustic and magnetic resonance imaging, offer promising tools for detecting and monitoring placental hypoxia. Integrating molecular and imaging biomarkers may revolutionize the detection and monitoring of placental hypoxia, improving pregnancy outcomes and reducing long-term health complications. This review describes current research on molecular and imaging biomarkers of placental hypoxia both in human and animal studies and aims to explore the benefits of an integrated approach throughout gestation.},
	year = {2023},
	eissn = {2073-4409},
	orcid-numbers = {Al Darwish, Fatimah M./0000-0002-1011-2669; Meijerink, Lotte/0000-0002-5914-4186; Coolen, Bram F./0000-0003-3946-653X; Strijkers, Gustav J./0000-0001-6700-5058; Bekker, Mireille/0000-0002-7372-4291; Terstappen, Fieke/0000-0002-6587-1320}
}

@inbook{MTMT:34064023,
	title = {Potential Value and Application of Liquid Biopsy in Tumor, Neurodegeneration, and Muscle Degenerative Diseases},
	url = {https://m2.mtmt.hu/api/publication/34064023},
	author = {Chen, Lin and Yang, Jun and Xu, Guodong and Wu, Yuxiang},
	booktitle = {Liquid Biopsies: Methods and Protocols},
	doi = {10.1007/978-1-0716-3346-5_22},
	unique-id = {34064023},
	year = {2023},
	pages = {317-335}
}

@article{MTMT:33059360,
	title = {The exosome: a review of current therapeutic roles and capabilities in human reproduction},
	url = {https://m2.mtmt.hu/api/publication/33059360},
	author = {Dimik, Marko and Abeysinghe, Pevindu and Logan, Jayden and Mitchell, Murray},
	doi = {10.1007/s13346-022-01225-3},
	journal-iso = {DRUG DELIV TRANSLAT RES},
	journal = {DRUG DELIVERY AND TRANSLATIONAL RESEARCH},
	volume = {13},
	unique-id = {33059360},
	issn = {2190-393X},
	abstract = {Exosomes are nano-vesicles (30–150 nm) which may be useful as therapeutic delivery vehicles and as diagnostic biomarkers. Exosomes are produced naturally within the human body and therefore are not prone to immunogenicity effects which would otherwise destroy unelicited foreign bodies. Clinically, they have been regarded as ideal candidates for applications relating to biomarker developments for the early detection of different diseases. Furthermore, exosomes may be of interest as potential drug delivery vehicles, which may improve factors such as bioavailability of loaded molecular cargo, side effect profiles, off-target effects, and pharmacokinetics of drug molecules. In this review, the therapeutic potential of exosomes and their use as clinical biomarkers for early diagnostics will be explored, alongside exosomes as therapeutic delivery vehicles. This review will evaluate techniques for cargo loading, and the capacity of loaded exosomes to improve various reproductive disease states. It becomes important, therefore, to consider factors such as loading efficiency, loading methods, cell viability, exosomal sources, exosome isolation, and the potential therapeutic benefits of exosomes. Issues related to targeted drug delivery will also be discussed. Finally, the variety of therapeutic cargo and the application of appropriate loading methods is explored, in the context of establishing clinical utility.},
	year = {2023},
	eissn = {2190-3948},
	pages = {473-502},
	orcid-numbers = {Dimik, Marko/0000-0001-8046-8794; Abeysinghe, Pevindu/0000-0001-9354-352X; Mitchell, Murray/0000-0002-6167-7176}
}

@article{MTMT:33682721,
	title = {Proteomic profile of extracellular vesicles in maternal plasma of women with fetal death},
	url = {https://m2.mtmt.hu/api/publication/33682721},
	author = {Gallo, D.M. and Fitzgerald, W. and Romero, R. and Gomez-Lopez, N. and Gudicha, D.W. and Than, Nándor Gábor and Bosco, M. and Chaiworapongsa, T. and Jung, E. and Meyyazhagan, A. and Suksai, M. and Gotsch, F. and Erez, O. and Tarca, A.L. and Margolis, L.},
	doi = {10.1080/14767058.2023.2177529},
	journal-iso = {J MATERN-FETAL NEO M},
	journal = {JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE},
	volume = {36},
	unique-id = {33682721},
	issn = {1476-7058},
	year = {2023},
	eissn = {1476-4954}
}

@article{MTMT:34224842,
	title = {A Machine Learning Model Based on microRNAs for the Diagnosis of Essential Hypertension},
	url = {https://m2.mtmt.hu/api/publication/34224842},
	author = {Jusic, Amela and Junuzovic, Inela and Hujdurovic, Ahmed and Zhang, Lu and Vausort, Mélanie and Devaux, Yvan},
	doi = {10.3390/ncrna9060064},
	journal-iso = {NON-CODING RNA},
	journal = {NON-CODING RNA},
	volume = {9},
	unique-id = {34224842},
	abstract = {Introduction: Hypertension is a major and modifiable risk factor for cardiovascular diseases. Essential, primary, or idiopathic hypertension accounts for 90–95% of all cases. Identifying novel biomarkers specific to essential hypertension may help in understanding pathophysiological pathways and developing personalized treatments. We tested whether the integration of circulating microRNAs (miRNAs) and clinical risk factors via machine learning modeling may provide useful information and novel tools for essential hypertension diagnosis and management. Materials and methods: In total, 174 participants were enrolled in the present observational case–control study, among which, there were 89 patients with essential hypertension and 85 controls. A discovery phase was conducted using small RNA sequencing in whole blood samples obtained from age- and sex-matched hypertension patients (n = 30) and controls (n = 30). A validation phase using RT-qPCR involved the remaining 114 participants. For machine learning, 170 participants with complete data were used to generate and evaluate the classification model. Results: Small RNA sequencing identified seven miRNAs downregulated in hypertensive patients as compared with controls in the discovery group, of which six were confirmed with RT-qPCR. In the validation group, miR-210-3p/361-3p/362-5p/378a-5p/501-5p were also downregulated in hypertensive patients. A machine learning support vector machine (SVM) model including clinical risk factors (sex, BMI, alcohol use, current smoker, and hypertension family history), miR-361-3p, and miR-501-5p was able to classify hypertension patients in a test dataset with an AUC of 0.90, a balanced accuracy of 0.87, a sensitivity of 0.83, and a specificity of 0.91. While five miRNAs exhibited substantial downregulation in hypertension patients, only miR-361-3p and miR-501-5p, alongside clinical risk factors, were consistently chosen in at least eight out of ten sub-training sets within the SVM model. Conclusions: This study highlights the potential significance of miRNA-based biomarkers in deepening our understanding of hypertension’s pathophysiology and in personalizing treatment strategies. The strong performance of the SVM model highlights its potential as a valuable asset for diagnosing and managing essential hypertension. The model remains to be extensively validated in independent patient cohorts before evaluating its added value in a clinical setting.},
	year = {2023},
	eissn = {2311-553X},
	orcid-numbers = {Zhang, Lu/0000-0001-7141-6730; Vausort, Mélanie/0000-0002-5261-7729; Devaux, Yvan/0000-0002-5321-8543}
}

@article{MTMT:34066420,
	title = {The Influence of Nicotine on Trophoblast-Derived Exosomes in a Mouse Model of Pathogenic Preeclampsia},
	url = {https://m2.mtmt.hu/api/publication/34066420},
	author = {Kubo, Ayane and Matsubara, Keiichi and Matsubara, Yuko and Nakaoka, Hirotomo and Sugiyama, Takashi},
	doi = {10.3390/ijms241311126},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {24},
	unique-id = {34066420},
	issn = {1661-6596},
	abstract = {Preeclampsia (PE) is a serious complication of pregnancy with a pathogenesis that is not fully understood, though it involves the impaired invasion of extravillous trophoblasts (EVTs) into the decidual layer during implantation. Because the risk of PE is actually decreased by cigarette smoking, we considered the possibility that nicotine, a critical component of tobacco smoke, might protect against PE by modifying the content of exosomes from EVTs. We investigated the effects of nicotine on our PE model mouse and evaluated blood pressure. Next, exosomes were extracted from nicotine-treated extravillous trophoblasts (HTR-8/SVneo), and the peptide samples were evaluated by DIA (Data Independent Acquisition) proteomic analysis following nano LC-MS/MS. Hub proteins were identified using bioinformatic analysis. We found that nicotine significantly reduced blood pressure in a PE mouse model. Furthermore, we identified many proteins whose abundance in exosomes was modified by nicotine treatment of EVTs, and we used bioinformatic annotation and network analysis to select five key hub proteins with potential roles in the pathogenesis or prevention of PE. EVT-derived exosomes might influence the pathogenesis of PE because the cargo delivered by exosomes can signal to and modify the receiving cells and their environment.},
	year = {2023},
	eissn = {1422-0067},
	orcid-numbers = {Matsubara, Keiichi/0000-0002-7488-8837}
}

@article{MTMT:34065462,
	title = {Placental Exosomes as Biomarkers for Maternal Diseases: Current Advances in Isolation, Characterization, and Detection},
	url = {https://m2.mtmt.hu/api/publication/34065462},
	author = {Nguyen, Cong Minh and Sallam, Mohamed and Islam, Md Sajedul and Clack, Kimberley and Soda, Narshone and Nguyen, Nam-Trung and Shiddiky, Muhammad J. A.},
	doi = {10.1021/acssensors.3c00689},
	journal-iso = {ACS SENSORS},
	journal = {ACS SENSORS},
	volume = {8},
	unique-id = {34065462},
	issn = {2379-3694},
	year = {2023},
	eissn = {2379-3694},
	pages = {2493-2513},
	orcid-numbers = {Nguyen, Cong Minh/0000-0003-1839-5111; Shiddiky, Muhammad J. A./0000-0003-4526-4109}
}

@article{MTMT:34403802,
	title = {Early prediction of pre-eclampsia using circulating placental exosomes. Newer insights.},
	url = {https://m2.mtmt.hu/api/publication/34403802},
	author = {Rao, Aishwarya and Shinde, Uma and Das, Dhanjit Kumar and Balasinor, Nafisa and Madan, Taruna},
	doi = {10.4103/ijmr.ijmr_2143_22},
	journal-iso = {INDIAN J MED RES},
	journal = {INDIAN JOURNAL OF MEDICAL RESEARCH},
	volume = {158},
	unique-id = {34403802},
	issn = {0971-5916},
	abstract = {Pre-eclampsia (PE), a multifactorial de novo hypertensive pregnancy disorder, is one of the leading causes of foeto-maternal morbidity and mortality. Currently, antihypertensive drugs are the first-line therapy for PE and evidence suggests that low-dose aspirin initiated early in high risk pregnancies may reduce the risk of development or severity of PE. However, an early prediction of this disorder remains an unmet clinical challenge. Several potential serum biomarkers associated with maternal immunoregulation and placental angiogenesis have been evaluated but are ineffective and inconsistent for early prediction. Although placental biomarkers would be more specific and sensitive in predicting the risk of PE, accessing the placenta during pregnancy is not feasible. Circulating placental exosomes (pEXO), originating from foeto-maternal interface, are being evaluated as the placenta's surrogate and the best source of non-invasive placental biomarkers. pEXO appear in the maternal circulation starting from six weeks of gestation and its dynamic biological cargo across pregnancy is associated with successful pregnancy outcomes. Therefore, monitoring changes in pEXO expression profiles could provide new insights into the prediction, diagnosis and treatment of PE. This narrative review comprehensively summarizes the available literature on the candidate predictive circulating biomarkers evaluated for PE to date. In particular, the review elucidates the current knowledge of distinct molecular signatures emanating from pEXO in pre-eclamptic women to support the discovery of novel early predictive biomarkers for effective intervention and management of the disease.},
	year = {2023},
	eissn = {0971-5916},
	pages = {385-396}
}

@{MTMT:34091236,
	title = {Identification of Plasma Metabolites Associated with Lung Cancer Survival},
	url = {https://m2.mtmt.hu/api/publication/34091236},
	author = {Wang, Peiyu and Yuan, Yuyao and Qiu, Mantang},
	booktitle = {Liquid Biopsies: Methods and Protocols},
	doi = {10.1007/978-1-0716-3346-5_12},
	unique-id = {34091236},
	year = {2023},
	pages = {181-193}
}

@article{MTMT:34047720,
	title = {New signaling kid on the block in the endocrine system: the role of extracellular vesicles},
	url = {https://m2.mtmt.hu/api/publication/34047720},
	author = {Xiong, Jiali and Fan, Yaotian and Wang, Yuxuan and Luo, Junyi and Chen, Ting and Sun, Jiajie and Xi, Qianyun and Zhang, Yongliang},
	doi = {10.1210/endocr/bqad099},
	journal-iso = {ENDOCRINOLOGY},
	journal = {ENDOCRINOLOGY},
	volume = {164},
	unique-id = {34047720},
	issn = {0013-7227},
	year = {2023},
	eissn = {1945-7170},
	orcid-numbers = {Xiong, Jiali/0000-0003-0274-2211; Zhang, Yongliang/0000-0001-5157-6059}
}

@article{MTMT:32636372,
	title = {Effects of microRNAs in hypertension disease},
	url = {https://m2.mtmt.hu/api/publication/32636372},
	author = {ALTINTAŞ, Nuray and TONK, Onur and SARICA YILMAZ, Özge},
	doi = {10.18621/eurj.855796},
	journal-iso = {EUR RES J},
	journal = {EUROPEAN RESEARCH JOURNAL},
	volume = {8},
	unique-id = {32636372},
	issn = {2149-3189},
	year = {2022},
	pages = {131-138}
}

@article{MTMT:32836977,
	title = {Involvement of extracellular vesicle-encapsulated miRNAs in human reproductive disorders: a systematic review},
	url = {https://m2.mtmt.hu/api/publication/32836977},
	author = {Barranco, Isabel and Salas-Huetos, Albert and Berlanga, Angel and Spinaci, Marcella and Yeste, Marc and Ribas-Maynou, Jordi},
	doi = {10.1071/RD21301},
	journal-iso = {REPROD FERT DEVELOP},
	journal = {REPRODUCTION FERTILITY AND DEVELOPMENT},
	volume = {34},
	unique-id = {32836977},
	issn = {1031-3613},
	keywords = {reproduction; SPERM; assisted reproduction; MICRORNAS; MICROVESICLES; Exosomes; Extracellular vesicles; Reproductive disorders},
	year = {2022},
	eissn = {1448-5990},
	pages = {751-755},
	orcid-numbers = {Salas-Huetos, Albert/0000-0001-5914-6862; Yeste, Marc/0000-0002-2209-340X; Ribas-Maynou, Jordi/0000-0002-9101-2044}
}

@article{MTMT:32605459,
	title = {Differential and targeted vesiculation: pathologic cellular responses to elevated arterial pressure},
	url = {https://m2.mtmt.hu/api/publication/32605459},
	author = {Brown, Paul A.},
	doi = {10.1007/s11010-021-04351-7},
	journal-iso = {MOL CELL BIOCHEM},
	journal = {MOLECULAR AND CELLULAR BIOCHEMISTRY},
	volume = {477},
	unique-id = {32605459},
	issn = {0300-8177},
	year = {2022},
	eissn = {1573-4919},
	pages = {1023-1040},
	orcid-numbers = {Brown, Paul A./0000-0003-3039-4752}
}

@article{MTMT:33298784,
	title = {The Role of microRNAs in Inflammation},
	url = {https://m2.mtmt.hu/api/publication/33298784},
	author = {Das, Kaushik and Rao, L. Vijaya Mohan},
	doi = {10.3390/ijms232415479},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {23},
	unique-id = {33298784},
	issn = {1661-6596},
	abstract = {Inflammation is a biological response of the immune system to various insults, such as pathogens, toxic compounds, damaged cells, and radiation. The complex network of pro- and anti-inflammatory factors and their direction towards inflammation often leads to the development and progression of various inflammation-associated diseases. The role of small non-coding RNAs (small ncRNAs) in inflammation has gained much attention in the past two decades for their regulation of inflammatory gene expression at multiple levels and their potential to serve as biomarkers and therapeutic targets in various diseases. One group of small ncRNAs, microRNAs (miRNAs), has become a key regulator in various inflammatory disease conditions. Their fine-tuning of target gene regulation often turns out to be an important factor in controlling aberrant inflammatory reactions in the system. This review summarizes the biogenesis of miRNA and the mechanisms of miRNA-mediated gene regulation. The review also briefly discusses various pro- and anti-inflammatory miRNAs, their targets and functions, and provides a detailed discussion on the role of miR-10a in inflammation.},
	year = {2022},
	eissn = {1422-0067},
	orcid-numbers = {Das, Kaushik/0000-0003-0386-0543}
}

@article{MTMT:32781783,
	title = {The implications of exosomes in pregnancy: emerging as new diagnostic markers and therapeutics targets},
	url = {https://m2.mtmt.hu/api/publication/32781783},
	author = {Ghafourian, Mehri and Mahdavi, Roya and Akbari Jonoush, Zahra and Sadeghi, Mahvash and Ghadiri, Nooshin and Farzaneh, Maryam and Mousavi Salehi, Abdolah},
	doi = {10.1186/s12964-022-00853-z},
	journal-iso = {CELL COMM SIGN},
	journal = {CELL COMMUNICATION AND SIGNALING},
	volume = {20},
	unique-id = {32781783},
	issn = {1478-811X},
	year = {2022},
	eissn = {1478-811X},
	orcid-numbers = {Farzaneh, Maryam/0000-0001-6239-8745}
}

@article{MTMT:33077919,
	title = {Exosomes as diagnostic tools},
	url = {https://m2.mtmt.hu/api/publication/33077919},
	author = {Gupta, Shweta and Mazumder, P.B.},
	doi = {10.1016/bs.acc.2022.06.004},
	journal-iso = {ADV CLIN CHEM},
	journal = {ADVANCES IN CLINICAL CHEMISTRY},
	volume = {110},
	unique-id = {33077919},
	issn = {0065-2423},
	abstract = {Exosomes have evolved into novel candidates as diagnostic tools due to their composition of proteins and nucleic acids and ability to cross hypoxic regions, the systemic circulation and blood vessel barriers. Exosomes are nano-sized extracellular vesicles that contain information from their source cells and are found in almost all body fluids. In this chapter, we have focused on basic biogenesis, contents, and functions of these unique particles, and provide a comprehensive discussion on their usefulness as novel diagnostic tools in various diseases. In addition, these unique features make them potential candidates for development of advanced therapeutics and monitoring thereof. © 2022 Elsevier Inc.},
	year = {2022},
	eissn = {2162-9471},
	pages = {117-144}
}

@article{MTMT:32595696,
	title = {Diagnostic Potential of Exosomal HypoxamiRs in the Context of Hypoxia–Sumoylation–HypoxamiRs in Early Onset Preeclampsia at the Preclinical Stage},
	url = {https://m2.mtmt.hu/api/publication/32595696},
	author = {Gusar, Vladislava and Timofeeva, Angelika and Chagovets, Vitaliy and Kan, Nataliya and Vysokikh, Mikhail and Marey, Maria and Karapetyan, Anna and Baev, Oleg and Sukhikh, Gennadiy},
	doi = {10.3390/life12010101},
	journal-iso = {LIFE-BASEL},
	journal = {LIFE-BASEL},
	volume = {12},
	unique-id = {32595696},
	year = {2022},
	eissn = {2075-1729},
	orcid-numbers = {Timofeeva, Angelika/0000-0003-2324-9653; Baev, Oleg/0000-0001-8572-1971}
}

@article{MTMT:32011224,
	title = {Extracellular vesicle microRNA in early versus late pregnancy with birth outcomes in the MADRES study},
	url = {https://m2.mtmt.hu/api/publication/32011224},
	author = {Howe, Caitlin G and Foley, Helen B and Kennedy, Elizabeth M and Eckel, Sandrah P and Chavez, Thomas a and Faham, Dema and Grubbs, Brendan H and Al-Marayati, Laila and Lerner, Deborah and Suglia, Shakira and Bastain, Theresa M and Marsit, Carmen J and Breton, Carrie V},
	doi = {10.1080/15592294.2021.1899887},
	journal-iso = {EPIGENETICS-US},
	journal = {EPIGENETICS},
	volume = {17},
	unique-id = {32011224},
	issn = {1559-2294},
	year = {2022},
	eissn = {1559-2308},
	pages = {269-285},
	orcid-numbers = {Howe, Caitlin G/0000-0002-4935-9298; Grubbs, Brendan H/0000-0002-1963-4922; Marsit, Carmen J/0000-0003-4566-150X}
}

@article{MTMT:32802661,
	title = {Hypoxia Induced Changes of Exosome Cargo and Subsequent Biological Effects},
	url = {https://m2.mtmt.hu/api/publication/32802661},
	author = {Jiang, Hongxia and Zhao, Hanqiu and Zhang, Mengzhe and He, Yuanzhou and Li, Xiaochen and Xu, Yongjian and Liu, Xiansheng},
	doi = {10.3389/fimmu.2022.824188},
	journal-iso = {FRONT IMMUNOL},
	journal = {FRONTIERS IN IMMUNOLOGY},
	volume = {13},
	unique-id = {32802661},
	issn = {1664-3224},
	year = {2022},
	eissn = {1664-3224}
}

@article{MTMT:33034176,
	title = {Classification of Preeclamptic Placental Extracellular Vesicles Using Femtosecond Laser Fabricated Nanoplasmonic Sensors},
	url = {https://m2.mtmt.hu/api/publication/33034176},
	author = {Kazemzadeh, Mohammadrahim and Martinez-Calderon, Miguel and Paek, Song Y. and Lowe, MoiMoi and Aguergaray, Claude and Xu, Weiliang and Chamley, Lawrence W. and Broderick, Neil G. R. and Hisey, Colin L.},
	doi = {10.1021/acssensors.2c00378},
	journal-iso = {ACS SENSORS},
	journal = {ACS SENSORS},
	volume = {7},
	unique-id = {33034176},
	issn = {2379-3694},
	keywords = {PREECLAMPSIA; femtosecond laser; Exosomes; SERS; Extracellular vesicles; Deep learning; machine learning placenta},
	year = {2022},
	eissn = {2379-3694},
	pages = {1698-1711}
}

@article{MTMT:32723312,
	title = {Study of serum miR-518 and its correlation with inflammatory factors in patients with gestational diabetes mellitus complicated with hypertensive disorder complicating pregnancy},
	url = {https://m2.mtmt.hu/api/publication/32723312},
	author = {Li, Yuanyuan and Han, Xinning and Yu, Lin},
	doi = {10.1016/j.ejogrb.2022.03.005},
	journal-iso = {EUR J OBSTET GYN R B (EJOG)},
	journal = {EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY},
	volume = {272},
	unique-id = {32723312},
	issn = {0301-2115},
	year = {2022},
	eissn = {1872-7654},
	pages = {198-205}
}

@article{MTMT:33262577,
	title = {Unfolding the role of placental-derived Extracellular Vesicles in Pregnancy: From homeostasis to pathophysiology},
	url = {https://m2.mtmt.hu/api/publication/33262577},
	author = {Ortega, Miguel A. and Fraile-Martínez, Oscar and García-Montero, Cielo and Paradela, Alberto and Asunción Sánchez-Gil, María and Rodriguez-Martin, Sonia and De León-Luis, Juan A. and Pereda-Cerquella, Claude and Bujan, Julia and Guijarro, Luis G. and Alvarez-Mon, Melchor and García-Honduvilla, Natalio},
	doi = {10.3389/fcell.2022.1060850},
	journal-iso = {FRONT CELL DEV BIOL},
	journal = {FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY},
	volume = {10},
	unique-id = {33262577},
	issn = {2296-634X},
	abstract = {The human placenta is a critical structure with multiple roles in pregnancy, including fetal nutrition and support, immunological, mechanical and chemical barrier as well as an endocrine activity. Besides, a growing body of evidence highlight the relevance of this organ on the maternofetal wellbeing not only during gestation, but also from birth onwards. Extracellular vesicles (EVs) are complex macromolecular structures of different size and content, acting as carriers of a diverse set of molecules and information from donor to recipient cells. Since its early development, the production and function of placental-derived EVs are essential to ensure an adequate progress of pregnancy. In turn, the fetus receives and produce their own EVs, highlighting the importance of these components in the maternofetal communication. Moreover, several studies have shown the clinical relevance of EVs in different obstetric pathologies such as preeclampsia, infectious diseases or gestational diabetes, among others, suggesting that they could be used as pathophysiological biomarkers of these diseases. Overall, the aim of this article is to present an updated review of the published basic and translational knowledge focusing on the role of placental-derived EVs in normal and pathological pregnancies. We suggest as well future lines of research to take in this novel and promising field.},
	year = {2022},
	eissn = {2296-634X},
	pages = {1}
}

@article{MTMT:32690510,
	title = {Small extracellular vesicles from plasma of women with preeclampsia increase myogenic tone and decrease endothelium-dependent relaxation of mouse mesenteric arteries},
	url = {https://m2.mtmt.hu/api/publication/32690510},
	author = {Powell, Juliana S. and Gandley, Robin E. and Lackner, Emily and Dolinish, Andrea and Ouyang, Yingshi and Powers, Robert W. and Morelli, Adrian E. and Hubel, Carl A. and Sadovsky, Yoel},
	doi = {10.1016/j.preghy.2022.02.005},
	journal-iso = {PREGNANCY HYPERTENS},
	journal = {PREGNANCY HYPERTENSION},
	volume = {28},
	unique-id = {32690510},
	issn = {2210-7789},
	year = {2022},
	eissn = {2210-7797},
	pages = {66-73}
}

@article{MTMT:32543517,
	title = {Extracellular vesicles in pharmacology: Novel approaches in diagnostics and therapy},
	url = {https://m2.mtmt.hu/api/publication/32543517},
	author = {Quadri, Zainuddin and Elsherbini, Ahmed and Bieberich, Erhard},
	doi = {10.1016/j.phrs.2021.105980},
	journal-iso = {PHARMACOL RES},
	journal = {PHARMACOLOGICAL RESEARCH},
	volume = {175},
	unique-id = {32543517},
	issn = {1043-6618},
	year = {2022},
	eissn = {1096-1186}
}

@article{MTMT:32908724,
	title = {The Role of Non-Coding RNAs in the Human Placenta},
	url = {https://m2.mtmt.hu/api/publication/32908724},
	author = {Zarkovic, Milena and Hufsky, Franziska and Markert, Udo R. and Marz, Manja},
	doi = {10.3390/cells11091588},
	journal-iso = {CELLS-BASEL},
	journal = {CELLS},
	volume = {11},
	unique-id = {32908724},
	keywords = {pregnancy; placenta; microRNA; Extracellular vesicles; Non-coding RNAs; circRNA},
	year = {2022},
	eissn = {2073-4409},
	orcid-numbers = {Hufsky, Franziska/0000-0002-9489-3182}
}

@article{MTMT:31612542,
	title = {Extracellular Vesicle-Mediated Vascular Cell Communications in Hypertension: Mechanism Insights and Therapeutic Potential of ncRNAs},
	url = {https://m2.mtmt.hu/api/publication/31612542},
	author = {Zhang, Ji-Ru and Sun, Hai-Jian},
	doi = {10.1007/s10557-020-07080-z},
	journal-iso = {CARDIOVASC DRUG THER},
	journal = {CARDIOVASCULAR DRUGS AND THERAPY},
	volume = {36},
	unique-id = {31612542},
	issn = {0920-3206},
	year = {2022},
	eissn = {1573-7241},
	pages = {157-172}
}

@article{MTMT:32001774,
	title = {Syncytiotrophoblast Derived Extracellular Vesicles in Relation to Preeclampsia},
	url = {https://m2.mtmt.hu/api/publication/32001774},
	author = {Cooke, William R. and Jones, Gabriel D. and Redman, Christopher W.G. and Vatish, Manu},
	doi = {10.1097/FM9.0000000000000093},
	journal-iso = {MATERNAL-FETAL MEDICINE},
	journal = {MATERNAL-FETAL MEDICINE},
	volume = {3},
	unique-id = {32001774},
	issn = {2096-6954},
	year = {2021},
	eissn = {2641-5895},
	pages = {151-160}
}

@article{MTMT:31778443,
	title = {Impact of exosome-mediated feto-maternal interactions on pregnancy maintenance and development of obstetric complications},
	url = {https://m2.mtmt.hu/api/publication/31778443},
	author = {Hashimoto, Ayako and Sugiura, Kei and Hoshino, Ayuko},
	doi = {10.1093/jb/mvaa137},
	journal-iso = {J BIOCHEM-TOKYO},
	journal = {JOURNAL OF BIOCHEMISTRY},
	volume = {169},
	unique-id = {31778443},
	issn = {0021-924X},
	year = {2021},
	eissn = {1756-2651},
	pages = {163-171}
}

@article{MTMT:32116691,
	title = {The predictive value of microRNA in early hypertensive disorder complicating pregnancy (HDCP).},
	url = {https://m2.mtmt.hu/api/publication/32116691},
	author = {Jin, Yan and Jia, Tingting and Wu, Xueling and Wang, Yanyan and Sun, Wenwen and Chen, Yajun and Wu, Guimei},
	journal-iso = {AM J TRANSL RES},
	journal = {AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH},
	volume = {13},
	unique-id = {32116691},
	issn = {1943-8141},
	abstract = {To examine the predictive value of microRNA (miRNA) in hypertensive disorder complicating pregnancy (HDCP).102 pregnant women with HDCP admitted to our hospital from March 2017 to June 2019 were recruited as the study cohort and randomly divided into an HDCP group, a mild preeclampsia group, and a severe preeclampsia group, with 34 patients in each group. In addition, 34 healthy pregnant women who underwent pregnancy tests in our hospital were recruited as the normal group. The relative expressions of plasma miR-19a, miR-126, and miRNA-210 in were measured. A Pearson correlation analysis was used to analyze the correlations between the miR-19a, miR-181b, and miRNA-210 expressions and the severity of HDCP. Receiver operating characteristic (ROC) curves were used to evaluate the diagnostic efficacy of the miR-19a, miR-126, and miRNA-210 expressions.The miR-19a and miRNA-210 expressions were higher in the HDCP group, the mild preeclampsia group, and the severe preeclampsia group than they were in the normal group, and the miR-126 expression was lower (all P<0.05). The miR-19a, miR-126, and miRNA-210 expressions were different among the four groups (P<0.05). The miR-19a and miRNA-210 expression levels in the severe preeclampsia group were higher than they were in the HDCP group, and the miR-126 expression was lower (P<0.05). A Pearson correlation analysis showed the miR-19a and miR-210 levels in the HDCP patients were positively correlated with the severity of the disease (P<0.05), and the miR-126 level is negatively correlated with disease severity (P<0.05). Our ROC curve analysis demonstrated that the miR-19a, miR-126, and miR-210 levels have a predictive value for HDCP. The areas under the curve were 0.800, 0.633, and 0.723, the sensitivities were 81.2%, 71.4%, and 80.2%, and the specificities were 73.5%, 67.5%, 81.5%. Additionally, the area under the curve of the combination of the three was 0.896, and the sensitivity and specificity were 90.5% and 93.9% respectively.miR-19a, miR-126, and miR-210 are strongly connected to the severity of HDCP and can be used as a sensitive indicator to predict HDCP patients clinically.},
	keywords = {microRNA; Pre-Eclampsia; Hypertension During Pregnancy},
	year = {2021},
	eissn = {1943-8141},
	pages = {7288-7293}
}

@article{MTMT:31908674,
	title = {Association of Circulating miRNA Expression with Preeclampsia, Its Onset, and Severity},
	url = {https://m2.mtmt.hu/api/publication/31908674},
	author = {Kolkova, Zuzana and Holubekova, Veronika and Grendar, Marian and Nachajova, Marcela and Zubor, Pavol and Pribulova, Terezia and Loderer, Dusan and Zigo, Imrich and Biringer, Kamil and Hornakova, Andrea},
	doi = {10.3390/diagnostics11030476},
	journal-iso = {DIAGNOSTICS},
	journal = {DIAGNOSTICS},
	volume = {11},
	unique-id = {31908674},
	issn = {2075-4418},
	year = {2021},
	eissn = {2075-4418},
	pages = {476},
	orcid-numbers = {Holubekova, Veronika/0000-0002-5979-8358; Biringer, Kamil/0000-0002-3471-0508}
}

@mastersthesis{MTMT:31778438,
	title = {A terhességi immuntolerancia mechanizmusának vizsgálatai},
	url = {https://m2.mtmt.hu/api/publication/31778438},
	author = {Kovács, Árpád Ferenc},
	doi = {10.14753/SE.2021.2430},
	unique-id = {31778438},
	year = {2021},
	orcid-numbers = {Kovács, Árpád Ferenc/0000-0002-7742-160X}
}

@article{MTMT:31932623,
	title = {Insight into the key points of preeclampsia pathophysiology: Uterine artery remodeling and the role of micrornas},
	url = {https://m2.mtmt.hu/api/publication/31932623},
	author = {Pankiewicz, K. and Fijałkowska, A. and Issat, T. and Maciejewski, T.M.},
	doi = {10.3390/ijms22063132},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {22},
	unique-id = {31932623},
	issn = {1661-6596},
	abstract = {Preeclampsia affects about 3–8% of all pregnancies. It represents a complex and multifaceted syndrome with at least several potential pathways leading to the development of disease. The main dogma in preeclampsia is the two-stage model of disease. Stage 1 (placental stage) takes place in early pregnancy and is thought to be impaired placentation due to inadequate trophoblastic invasion of the maternal spiral arteries that leads to reduced placental perfusion and release of numerous biological factors causing endothelial damage and development of acute maternal syndrome with systemic multiorgan failure (stage 2—the onset of maternal clinical symptoms, maternal stage). Recently, in the light of the vast body of evidence, two-stage model of preeclampsia has been updated with a few novel pathways leading to clinical manifestation in the second part of pregnancy. This paper reviews current state of knowledge about pathophysiology of preeclampsia and places particular focus on the recent advances in understanding of uterine artery remodeling alterations, as well as the role of microRNAs in preeclampsia. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.},
	keywords = {PREECLAMPSIA; microRNA; Two-stage model; Uterine artery remodeling},
	year = {2021},
	eissn = {1422-0067}
}

@mastersthesis{MTMT:32513996,
	title = {Роль неивазивных методов диагностики в оптимизации акушерской тактики при врастании и предлежании плаценты},
	url = {https://m2.mtmt.hu/api/publication/32513996},
	author = {Pirogova, M. M.},
	unique-id = {32513996},
	year = {2021}
}

@article{MTMT:32077778,
	title = {Role of Extracellular Vesicles in Placental Inflammation and Local Immune Balance},
	url = {https://m2.mtmt.hu/api/publication/32077778},
	author = {Wang, Zengfang and Yang, Ruizhen and Zhang, Jiaojiao and Wang, Pingping and Wang, Zengyan and Gao, Jian and Liu, Xue and Gu, Bingjie},
	doi = {10.1155/2021/5558048},
	journal-iso = {MEDIAT INFLAMM},
	journal = {MEDIATORS OF INFLAMMATION},
	volume = {2021},
	unique-id = {32077778},
	issn = {0962-9351},
	year = {2021},
	eissn = {1466-1861},
	orcid-numbers = {Gao, Jian/0000-0002-2379-9092; Liu, Xue/0000-0003-1133-9475}
}

@article{MTMT:31934967,
	title = {Placenta-Derived MicroRNAs in the Pathophysiology of Human Pregnancy},
	url = {https://m2.mtmt.hu/api/publication/31934967},
	author = {Xu, Peng and Ma, Yeling and Wu, Hongyu and Wang, Yan-Ling},
	doi = {10.3389/fcell.2021.646326},
	journal-iso = {FRONT CELL DEV BIOL},
	journal = {FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY},
	volume = {9},
	unique-id = {31934967},
	issn = {2296-634X},
	year = {2021},
	eissn = {2296-634X}
}

@article{MTMT:31367020,
	title = {Tracking placental development in health and disease},
	url = {https://m2.mtmt.hu/api/publication/31367020},
	author = {Aplin, John D. and Myers, Jenny E. and Timms, Kate and Westwood, Melissa},
	doi = {10.1038/s41574-020-0372-6},
	journal-iso = {NAT REV ENDOCRINOL},
	journal = {NATURE REVIEWS ENDOCRINOLOGY},
	volume = {16},
	unique-id = {31367020},
	issn = {1759-5029},
	year = {2020},
	eissn = {1759-5037},
	pages = {479-494}
}

@article{MTMT:31256520,
	title = {Extracellular Vesicles in Feto–Maternal Crosstalk and Pregnancy Disorders},
	url = {https://m2.mtmt.hu/api/publication/31256520},
	author = {Buca, Danilo and Bologna, Giuseppina and D’Amico, Alice and Cugini, Sara and Musca, Francesca and Febbo, Melania and D’Arcangelo, Dolores and Buca, Davide and Simeone, Pasquale and Liberati, Marco and Vitacolonna, Ester and Miscia, Sebastiano and D’Antonio, Francesco and Lanuti, Paola},
	doi = {10.3390/ijms21062120},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {21},
	unique-id = {31256520},
	issn = {1661-6596},
	year = {2020},
	eissn = {1422-0067}
}

@mastersthesis{MTMT:31871968,
	title = {Investigating Placental MicroRNAs in Preeclampsia and Optimising a Gene Therapy Strategy for Targeting the Placenta},
	url = {https://m2.mtmt.hu/api/publication/31871968},
	author = {Frazier, S. E.},
	unique-id = {31871968},
	year = {2020}
}

@article{MTMT:31407098,
	title = {The Potential Role of Serum Exosomes in Preeclampsia},
	url = {https://m2.mtmt.hu/api/publication/31407098},
	author = {Gao, Xuelin and Shao, Lulu and Ge, Xinying and Zhang, Long and Chen, Dexin and He, Rongxia},
	doi = {10.2174/1389200221666200525152441},
	journal-iso = {CURR DRUG METAB},
	journal = {CURRENT DRUG METABOLISM},
	volume = {21},
	unique-id = {31407098},
	issn = {1389-2002},
	year = {2020},
	eissn = {1875-5453},
	pages = {352-356}
}

@article{MTMT:31350673,
	title = {Diagnostic Potential of MicroRNAs as Biomarkers in the Detection of Preeclampsia},
	url = {https://m2.mtmt.hu/api/publication/31350673},
	author = {Hornakova, A. and Kolkova, Z. and Holubekova, V. and Loderer, D. and Lasabova, Z. and Biringer, K. and Halasova, E.},
	doi = {10.1089/gtmb.2019.0264},
	journal-iso = {GENET TEST MOL BIOMA},
	journal = {GENETIC TESTING AND MOLECULAR BIOMARKERS},
	volume = {24},
	unique-id = {31350673},
	issn = {1945-0265},
	year = {2020},
	eissn = {1945-0257},
	pages = {321-327}
}

@article{MTMT:31336439,
	title = {Transfection of maternal cells with placental extracellular vesicles in preeclampsia},
	url = {https://m2.mtmt.hu/api/publication/31336439},
	author = {Konečná, Barbora and Vlková, Barbora and Repiská, Gabriela and Tóthová, Ľubomíra},
	doi = {10.1016/j.mehy.2020.109721},
	journal-iso = {MED HYPOTHESES},
	journal = {MEDICAL HYPOTHESES},
	volume = {141},
	unique-id = {31336439},
	issn = {0306-9877},
	year = {2020},
	eissn = {1532-2777}
}

@article{MTMT:31143904,
	title = {Unique microRNA Signals in Plasma Exosomes from Pregnancies Complicated by Preeclampsia},
	url = {https://m2.mtmt.hu/api/publication/31143904},
	author = {Li, Hui and Ouyang, Yingshi and Sadovsky, Elena and Parks, W. Tony and Chu, Tianjiao and Sadovsky, Yoel},
	doi = {10.1161/HYPERTENSIONAHA.119.14081},
	journal-iso = {HYPERTENSION},
	journal = {HYPERTENSION},
	volume = {75},
	unique-id = {31143904},
	issn = {0194-911X},
	year = {2020},
	eissn = {1524-4563},
	pages = {762-771}
}

@article{MTMT:31306484,
	title = {Expression and role of miR‑338‑3p in peripheral blood and placenta of patients with pregnancy‑induced hypertension},
	url = {https://m2.mtmt.hu/api/publication/31306484},
	author = {Li, Jun and Wu, Yan and Liu, Hui},
	doi = {10.3892/etm.2020.8719},
	journal-iso = {EXP THER MED},
	journal = {EXPERIMENTAL AND THERAPEUTIC MEDICINE},
	volume = {20},
	unique-id = {31306484},
	issn = {1792-0981},
	year = {2020},
	eissn = {1792-1015},
	pages = {418-426}
}

@article{MTMT:32514006,
	title = {Syncytiotrophoblast-derived extracellular products associated with preeclampsia},
	url = {https://m2.mtmt.hu/api/publication/32514006},
	author = {Pérez-Roncero, Gonzalo R. and López-Baena, María T. and Pérez-López, Faustino R. and Escobar-Valdivieso, Gustavo S. and Chedraui, Peter and Hidalgo, Luis},
	journal-iso = {EGO},
	journal = {EUROPEAN GYNECOLOGY AND OBSTETRICS},
	volume = {2},
	unique-id = {32514006},
	year = {2020},
	eissn = {2710-2580},
	pages = {90-93}
}

@article{MTMT:31377934,
	title = {OSCC Exosomes Regulate miR-210-3p Targeting EFNA3 to Promote Oral Cancer Angiogenesis through the PI3K/AKT Pathway},
	url = {https://m2.mtmt.hu/api/publication/31377934},
	author = {Wang, Hui and Wang, Lin and Zhou, Xiaocheng and Luo, Xinyue and Liu, Ke and Jiang, Erhui and Chen, Yang and Shao, Zhe and Shang, Zhengjun},
	doi = {10.1155/2020/2125656},
	journal-iso = {BIOMED RES INT},
	journal = {BIOMED RESEARCH INTERNATIONAL},
	volume = {2020},
	unique-id = {31377934},
	issn = {2314-6133},
	year = {2020},
	eissn = {2314-6141},
	orcid-numbers = {Jiang, Erhui/0000-0003-4668-026X; Shao, Zhe/0000-0003-2357-3760; Shang, Zhengjun/0000-0002-4884-8129}
}

@article{MTMT:31167001,
	title = {Clinical application of exosomes and circulating microRNAs in the diagnosis of pregnancy complications and foetal abnormalities},
	url = {https://m2.mtmt.hu/api/publication/31167001},
	author = {Yang, H. and Ma, Q. and Wang, Y. and Tang, Z.},
	doi = {10.1186/s12967-020-02227-w},
	journal-iso = {J TRANSL MED},
	journal = {JOURNAL OF TRANSLATIONAL MEDICINE},
	volume = {18},
	unique-id = {31167001},
	issn = {1479-5876},
	year = {2020},
	eissn = {1479-5876}
}

@article{MTMT:31252712,
	title = {Extracellular vesicles in normal pregnancy and pregnancy‐related diseases},
	url = {https://m2.mtmt.hu/api/publication/31252712},
	author = {Zhang, Jiayin and Li, Haibo and Fan, Boyue and Xu, Wenrong and Zhang, Xu},
	doi = {10.1111/jcmm.15144},
	journal-iso = {J CELL MOL MED},
	journal = {JOURNAL OF CELLULAR AND MOLECULAR MEDICINE},
	volume = {24},
	unique-id = {31252712},
	issn = {1582-1838},
	year = {2020},
	eissn = {1582-4934},
	pages = {4377-4388},
	orcid-numbers = {Zhang, Xu/0000-0003-3492-4618}
}

@article{MTMT:31397044,
	title = {Application of exosomes as liquid biopsy in clinical diagnosis},
	url = {https://m2.mtmt.hu/api/publication/31397044},
	author = {Zhou, Biting and Xu, Kailun and Zheng, Xi and Chen, Ting and Wang, Jian and Song, Yongmao and Shao, Yingkuan and Zheng, Shu},
	doi = {10.1038/s41392-020-00258-9},
	journal-iso = {SIGNAL TRANSDUCT TAR},
	journal = {SIGNAL TRANSDUCTION AND TARGETED THERAPY},
	volume = {5},
	unique-id = {31397044},
	issn = {2095-9907},
	year = {2020},
	eissn = {2059-3635}
}

@{MTMT:30859819,
	title = {Current Trends on Exploring the Multifaceted Role of Extracellular Vesicles in Human Pregnancy},
	url = {https://m2.mtmt.hu/api/publication/30859819},
	author = {Kovács, Árpád Ferenc},
	booktitle = {Extracellular Vesicles},
	unique-id = {30859819},
	year = {2019},
	pages = {37-60},
	orcid-numbers = {Kovács, Árpád Ferenc/0000-0002-7742-160X}
}

@article{MTMT:30401681,
	title = {Circulating exosomal and Argonaute-bound microRNAs in preeclampsia},
	url = {https://m2.mtmt.hu/api/publication/30401681},
	author = {Biró, Orsolya and Fóthi, Ábel and Alasztics, Bálint and Nagy, Bálint and Orbán, Tamás I. and Rigó, János},
	doi = {10.1016/j.gene.2019.01.012},
	journal-iso = {GENE},
	journal = {GENE},
	volume = {692},
	unique-id = {30401681},
	issn = {0378-1119},
	abstract = {Introduction
		microRNAs (miRNAs) play important role in the regulation of placental development, and abnormal miRNA expression is associated with preeclampsia (PE). miRNAs are released from trophoblast cells to maternal blood flow, where they are highly stable, being encapsulated inside extracellular vesicles, like exosomes or bound to Argonaute proteins. In PE, placental dysfunction leads to aberrant extracellular miRNA secretion. hsa-miR-210 is a hypoxia-sensitive miRNA found to be upregulated in PE; however, it is unknown whether it is the cause or the consequence of the disease.
		
		Objective
		Our aim was to analyze the expression of several miRNAs, including hsa-miR-210 in placenta, exosome and Ago-bound fractions comparing normal (N) and PE pregnancies. We performed in vitro analyses of extracellular hsa-miR-210 secretion of trophoblast cell cultures (of villous and extravillous origin) under hypoxic condition.
		
		Methods
		PE and N placenta samples were collected from C-sections, and blood samples were drawn from each pregnant woman in the third trimester. HTR-8 and JAR cell lines were cultured in exosome-free media and treated with hypoxia-mimetic agents. Exosome and Ago-bound fractions were isolated by membrane affinity spin column method from plasma and cell media. Short RNAs were extracted from exosomes and vesicle-free fractions, and total-RNA was isolated from the placenta samples. The RNA purity and concentration were measured by spectrophotometry. Expression analysis was carried out by qPCR with specific primers to target and reference miRNAs.
		
		Results
		The level of hsa-miR-210 was significantly higher in PE placentas, which could cause a minor increase of exosomal and a high elevation of Ago-bound miR-210 in circulation. Hypoxia lead to intracellular hsa-miR-210 upregulation in trophoblast cell lines. In extravillous cell (HTR-8) media, only the level of exosomal hsa-miR-210 was increased but no change in Ago-bound hsa-miR-210 level was observed. In contrast, in villous cell (JAR) media, the level of exosomal hsa-miR-210 was increased and enhanced release of Ago-bound hsa-miR-210 was also observed.
		
		Conclusion
		Based on our data, we postulate that in PE, exosomal hsa-miR-210 is secreted actively from the trophoblast, and by intercellular communication, it may have a role in disease etiology. In addition, there is a passive release of Ago-bound hsa-miR-210 into the circulation, which may represent by-products of cell-death and is thereby a possible consequence of the disease.},
	year = {2019},
	eissn = {1879-0038},
	pages = {138-144},
	orcid-numbers = {Biró, Orsolya/0000-0002-4300-3602; Alasztics, Bálint/0000-0002-4011-8439; Nagy, Bálint/0000-0002-0295-185X; Orbán, Tamás I./0000-0002-3424-3428; Rigó, János/0000-0003-2762-6516}
}

@mastersthesis{MTMT:30859380,
	title = {A mikroRNS-ek patogenetikai szerepe és expressziós mintázata praeeclampsiában},
	url = {https://m2.mtmt.hu/api/publication/30859380},
	author = {Biró, Orsolya},
	doi = {10.14753/SE.2019.2269},
	unique-id = {30859380},
	year = {2019},
	orcid-numbers = {Biró, Orsolya/0000-0002-4300-3602}
}

@article{MTMT:31381570,
	title = {The roles of placenta-derived miRNAs in the occurrence and development of preeclampsia and their clinical values},
	url = {https://m2.mtmt.hu/api/publication/31381570},
	author = {Duan, Y. and Jiang, L. and Li, L. and Li, Q.},
	doi = {10.3760/cma.j.issn.1009-9158.2019.07.015},
	journal-iso = {CHIN J LAB MED},
	journal = {CHINESE JOURNAL OF LABORATORY MEDICINE},
	volume = {42},
	unique-id = {31381570},
	issn = {1009-9158},
	abstract = {Preeclampsia (PE) is a serious disease that threatens the health of maternal and newborn. However, the etiology and pathogenesis of PE remains elusive. Micro-RNA, a class of noncoding small single stranded RNA, plays an important role in the physiologic and pathophysiologic process of PE. In recent years, some researchers classified the placenta-derived miRNAs and investigated their roles in the occurrence of PE and their potential value in the PE early diagnosis. These findings are summarized in the review. Copyright © 2019 by the Chinese Medical Association.},
	keywords = {placenta; MICRORNAS; Pre-Eclampsia},
	year = {2019},
	pages = {575-580}
}

@article{MTMT:30683358,
	title = {Effect of Hypoxia-Induced MicroRNA-210 Expression on Cardiovascular Disease and the Underlying Mechanism},
	url = {https://m2.mtmt.hu/api/publication/30683358},
	author = {Guan, Yinuo and Song, Xianjing and Sun, Wei and Wang, Yiran and Liu, Bin},
	doi = {10.1155/2019/4727283},
	journal-iso = {OXID MED CELL LONGEV},
	journal = {OXIDATIVE MEDICINE AND CELLULAR LONGEVITY},
	volume = {2019},
	unique-id = {30683358},
	issn = {1942-0900},
	year = {2019},
	eissn = {1942-0994}
}

@article{MTMT:30329471,
	title = {Elevated MicroRNA-181a-5p Contributes to Trophoblast Dysfunction and Preeclampsia.},
	url = {https://m2.mtmt.hu/api/publication/30329471},
	author = {Huang, Xiaohao and Wu, Lan and Zhang, Guoying and Tang, Ranran and Zhou, Xue},
	doi = {10.1177/1933719118808916},
	journal-iso = {REPROD SCI},
	journal = {REPRODUCTIVE SCIENCES},
	volume = {26},
	unique-id = {30329471},
	issn = {1933-7191},
	abstract = {It has been demonstrated that preeclampsia is associated with alterations in placental microRNA expression. Previous reports have shown that hsa-miR-181a-5p is overexpressed in human preeclamptic placenta compared with normotensive placenta. The purpose of this study was to explore whether upregulated hsa-miR-181a-5p expression is involved in the ontogenesis of preeclampsia.Twenty preeclamptic placentas and 20 normotensive placentas were obtained from nulliparous women by cesarean section. Expression of hsa-miR-181a-5p in placenta tissues and human trophoblast cell lines was analyzed by reverse transcription polymerase chain reaction. The trophoblast cell lines (HTR-8/SVneo and JAR) were transfected with specific oligonucleotides to upregulate miR-181a-5p expression. The effect of miR-181a-5p expression on proliferation, cell cycle, apoptosis, and invasion in HTR-8/SVneo and JAR cells was then investigated.It was demonstrated that hsa-miR-181a-5p expression was upregulated in preeclamptic placentas and that it may trigger antiproliferation and inhibition of cell cycle progression, induce apoptosis, and suppress invasion in HTR-8/SVneo and JAR cells.Anomalously upregulated hsa-miR-181a-5p expression could contribute to trophoblast dysfunction and may be a crucial factor in the pathogenesis of preeclampsia.},
	keywords = {placenta; PREECLAMPSIA; Hsa-miR-181a-5p; trophoblast cell lines},
	year = {2019},
	eissn = {1933-7205},
	pages = {1121-1129}
}

@article{MTMT:30740414,
	title = {The relationship between molecular content of mesenchymal stem cells derived exosomes and their potentials: opening the way for exosomes based therapeutics},
	url = {https://m2.mtmt.hu/api/publication/30740414},
	author = {Jafari, Davod and Malih, Sara and Eslami, Seyed Sadegh and Jafari, Rasool and Darzi, Leila and Tarighi, Parastoo and Samadikuchaksaraei, Ali},
	doi = {10.1016/j.biochi.2019.07.009},
	journal-iso = {BIOCHIMIE},
	journal = {BIOCHIMIE},
	volume = {165},
	unique-id = {30740414},
	issn = {0300-9084},
	year = {2019},
	eissn = {1638-6183},
	pages = {76-89},
	orcid-numbers = {Malih, Sara/0000-0002-5400-0773}
}

@article{MTMT:30770243,
	title = {The role of epigenetic changes in preeclampsia},
	url = {https://m2.mtmt.hu/api/publication/30770243},
	author = {Kamrani, Amin and Alipourfard, Iraj and Ahmadi-Khiavi, Homayoon and Yousefi, Mehdi and Rostamzadeh, Davood and Izadi, Morteza and Ahmadi, Majid},
	doi = {10.1002/biof.1542},
	journal-iso = {BIOFACTORS},
	journal = {BIOFACTORS},
	volume = {45},
	unique-id = {30770243},
	issn = {0951-6433},
	abstract = {Preeclampsia (PE) is a disorder affecting 2-10% of pregnancies and has a major role for perinatal and maternal mortality and morbidity. PE can be occurred by initiation of new hypertension combined with proteinuria after 20 weeks gestation, as well as various reasons such as inflammatory cytokines, poor trophoblast invasion can be related with PE disease. Environmental factors can cause epigenetic changes including DNA methylation, microRNAs (miRNAs), and histone modification that may be related to different diseases such as PE. Abnormal DNA methylation during placentation is the most important epigenetic factor correlated with PE. Moreover, changes in histone modification like acetylation and also the effect of overregulation or low regulation of miRNAs or long noncoding RNAs on variety signaling pathways can be resulted in PE. The aim of this review is to describe of studies about epigenetic changes in PE and its therapeutic strategies.},
	keywords = {PREECLAMPSIA; microRNA; DNA methylation; epigenetics; histone modification},
	year = {2019},
	eissn = {1872-8081},
	pages = {712-724}
}

@article{MTMT:30920237,
	title = {Exosomes-Associated DNA-New Marker in Pregnancy Complications?},
	url = {https://m2.mtmt.hu/api/publication/30920237},
	author = {Konecna, Barbora and Tothova, Lubomira and Repiska, Gabriela},
	doi = {10.3390/ijms20122890},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {20},
	unique-id = {30920237},
	issn = {1661-6596},
	abstract = {Despite a large number of studies, the etiology of pregnancy complications remains unknown. The involvement of cell-free DNA or fetal cell-free DNA in the pathogenesis of pregnancy complications is currently being hypothesized. Cell-free DNA occurs in different forms-free; part of neutrophil extracellular traps; or as recently discovered, carried by extracellular vesicles. Cell-free DNA is believed to activate an inflammatory pathway, which could possibly cause pregnancy complications. It could be hypothesized that DNA in its free form could be easily degraded by nucleases to prevent the inflammatory activation. However, recently, there has been a growing interest in the role of exosomes, potential protectors of cell-free DNA, in pregnancy complications. Most of the interest from recent years is directed towards the micro RNA carried by exosomes. However, exosome-associated DNA in relation to pregnancy complications has not been truly studied yet. DNA, as an important cargo of exosomes, has been so far studied mostly in cancer research. This review collects all the known information on the topic of not only exosome-associated DNA but also some information on vesicles-associated DNA and the studies regarding the role of exosomes in pregnancy complications from recent years. It also suggests possible analysis of exosome-associated DNA in pregnancy from plasma and emphasizes the importance of such analysis for future investigations of pregnancy complications. A major obstacle to the advancement in this field is the proper uniformed technique for exosomes isolation. Similarly, the sensitivity of methods analyzing a small fraction of DNA, potentially fetal DNA, carried by exosomes is variable.},
	keywords = {NUCLEIC-ACIDS; PREECLAMPSIA; growth retardation; TROPHOBLAST CELLS; INTRAUTERINE GROWTH RESTRICTION; Exosomes; Extracellular vesicles; Extracellular vesicles; CELL-FREE DNA; CELL-FREE DNA; GESTATIONAL DIABETES-MELLITUS; Maternal circulation; Biochemistry & Molecular Biology; FETAL DNA; FREE FETAL DNA; PLACENTAL EXOSOMES},
	year = {2019},
	eissn = {1422-0067},
	orcid-numbers = {Tothova, Lubomira/0000-0001-9162-4916}
}

@article{MTMT:27706006,
	title = {Roles of microRNAs in preeclampsia},
	url = {https://m2.mtmt.hu/api/publication/27706006},
	author = {Lv, Yan and Lu, Cheng and Ji, Xiaohong and Miao, Zhijing and Long, Wei and Ding, Hongjuan and Lv, Mingming},
	doi = {10.1002/jcp.27291},
	journal-iso = {J CELL PHYSIOL},
	journal = {JOURNAL OF CELLULAR PHYSIOLOGY},
	volume = {234},
	unique-id = {27706006},
	issn = {0021-9541},
	year = {2019},
	eissn = {1097-4652},
	pages = {1052-1061}
}

@article{MTMT:30738986,
	title = {MicroRNA-378 protects human umbilical vein endothelial cells from injuries by soluble CD226 through down-regulating the expression of soluble CD226 in natural killer cells},
	url = {https://m2.mtmt.hu/api/publication/30738986},
	author = {Xu, Huiying and Du, Yu and He, Jing and Wang, Liping and Sun, Gaogao},
	doi = {10.1080/13102818.2019.1640075},
	journal-iso = {BIOTECHNOL BIOTEC EQ},
	journal = {BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT},
	volume = {33},
	unique-id = {30738986},
	issn = {1310-2818},
	year = {2019},
	eissn = {1314-3530},
	pages = {1097-1107}
}

@article{MTMT:30859131,
	title = {Hypoxia-induced exosomes promote hepatocellular carcinoma proliferation and metastasis via miR-1273f transfer},
	url = {https://m2.mtmt.hu/api/publication/30859131},
	author = {Yu, You and Min, Zou and Zhou Zhihang, ZHIhang and Linhong, Mao and Tao, Ran and Yan, Liu and Song, He},
	doi = {10.1016/j.yexcr.2019.111649},
	journal-iso = {EXP CELL RES},
	journal = {EXPERIMENTAL CELL RESEARCH},
	volume = {385},
	unique-id = {30859131},
	issn = {0014-4827},
	abstract = {Exosomes are present within the local hypoxic tumor microenvironment, where they are able to transfer microRNAs between cells, thereby, effectively mediating cell-cell communication. Hypoxia plays a pivotal role in the progression of many tumor types such as hepatocellular carcinoma (HCC), but how hypoxia-induced exosomes in HCC affect HCC cells remains uncertain. In the present study, we found that hypoxic conditions induced increased exosomal production by HCC cells, and these exosomes, in turn, enhanced the proliferation, migration, and invasiveness in addition to epithelial-to-mesenchymal transition (EMT) in HCC cells under normoxic conditions. When we analyzed these exosomes, we found that miR-1273f were present at higher levels under hypoxic conditions, and we determined that this miRNA was responsible for directly replicating the effects of hypoxic exosomes within HCC cells, in addition to activating the Wnt/β-catenin signaling. We finally identified LHX6, which is a known inhibitor of the Wnt/β-catenin pathway, to be a miR-1273f target. These results, thus, provide evidence that hypoxic conditions can lead HCC cells to express increased exosomes that facilitate miR-1273f expression in normoxic cells, thereby enhancing their malignant phenotype at least in part by targeting LHX6 for downregulation.},
	keywords = {Hepatocellular carcinoma; HYPOXIA; Exosomes; LHX6; miR-1273f},
	year = {2019},
	eissn = {1090-2422}
}

@article{MTMT:32513992,
	title = {The Regulation Role of Exosomes in Mammalian Pregnancy},
	url = {https://m2.mtmt.hu/api/publication/32513992},
	author = {ZHAO, Le and YANG, Haili and ZHANG, Rong and YANG, Yongheng and LI, Jialu and ZHOU, Heming and WANG, Pan and ZHAO, Yongju},
	journal-iso = {ACTA VET ZOOTECH SIN},
	journal = {ACTA VETERINARIA ET ZOOTECHNICA SINICA / XUMU SHOUYI XUEBAO},
	volume = {50},
	unique-id = {32513992},
	issn = {0366-6964},
	year = {2019},
	pages = {2371-2378}
}

@article{MTMT:32613885,
	title = {妊娠期高血压患者中miRNA210表达与尿微量白蛋白/肌酐比的相关性研究},
	url = {https://m2.mtmt.hu/api/publication/32613885},
	author = {赵得雄, . and 靳紫薇, . and 李宗英, . and 王烈宏, . and 谢玲, .},
	journal-iso = {Chinese Journal of Clinical Obstetrics and Gynecology},
	journal = {Chinese Journal of Clinical Obstetrics and Gynecology},
	volume = {20},
	unique-id = {32613885},
	issn = {1672-1861},
	year = {2019},
	pages = {551-552}
}

@article{MTMT:3357249,
	title = {A mikro-RNS-ek patogenetikai szerepe és expressziós mintázata praeeclampsiában},
	url = {https://m2.mtmt.hu/api/publication/3357249},
	author = {Biró, Orsolya and Rigó, János},
	doi = {10.1556/650.2018.31025},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {159},
	unique-id = {3357249},
	issn = {0030-6002},
	abstract = {Preeclampsia is the leading cause of maternal and fetal morbidity and mortality that affects 3-8% of pregnancies worldwide. Its main symptoms include new onset of high blood pressure and proteinuria after 20 weeks of pregnancy. The cause of the disease is still debated. microRNAs are short, non-coding RNA molecules that play a pivotal part in the posttranscriptional regulation of eukaryotic genes. They are involved in fine-tuning of vital physiological processes such as cell cycle, proliferation, differentiation and cell death. In genomic studies, hundreds of microRNAs were detected in the placenta, which are supposed to regulate placental development and contribute to uncomplicated pregnancy. Several studies have reported changes in the expression of microRNAs in pregnancy. Abnormal microRNA expression may have a role in the development of preeclampsia as it affects the proliferation, migration, and invasion of the trophoblast cells, spiral artery remodeling, and angiogenesis. Some placental microRNAs (e.g., the C19MC microRNA cluster) are able to reach the maternal circulation through their release via exosomes from the trophoblast layer. These 'circulating' microRNA molecules can be applied as biomarkers for the detection of various placental disorders owing to their stability and specificity. Orv Hetil. 2018; 159(14): 547-556.},
	year = {2018},
	eissn = {1788-6120},
	pages = {547-556},
	orcid-numbers = {Biró, Orsolya/0000-0002-4300-3602; Rigó, János/0000-0003-2762-6516}
}

@mastersthesis{MTMT:30859220,
	title = {Maternal Folic Acid Supplementation and Its Effects on Metabolic and Epigenetic Regulatory Gene Networks in Offspring},
	url = {https://m2.mtmt.hu/api/publication/30859220},
	author = {Chu, Wing Hong},
	unique-id = {30859220},
	year = {2018}
}

@article{MTMT:27516581,
	title = {Extracellular vesicles generated by placental tissues ex vivo: A transport system for immune mediators and growth factors},
	url = {https://m2.mtmt.hu/api/publication/27516581},
	author = {Fitzgerald, Wendy and Gomez-Lopez, Nardhy and Erez, Offer and Romero, Roberto and Margolis, Leonid},
	doi = {10.1111/aji.12860},
	journal-iso = {AM J REPROD IMMUNOL},
	journal = {AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY},
	volume = {80},
	unique-id = {27516581},
	issn = {1046-7408},
	year = {2018},
	eissn = {1600-0897},
	orcid-numbers = {Gomez-Lopez, Nardhy/0000-0002-3406-5262; Romero, Roberto/0000-0002-4448-5121}
}

@article{MTMT:27546979,
	title = {miRNAs in pregnancy-related complications: an update},
	url = {https://m2.mtmt.hu/api/publication/27546979},
	author = {Mavreli, D and Papantoniou, N and Kolialexi, A},
	doi = {10.1080/14737159.2018.1480939},
	journal-iso = {EXPERT REV MOL DIAGN},
	journal = {EXPERT REVIEW OF MOLECULAR DIAGNOSTICS},
	volume = {18},
	unique-id = {27546979},
	issn = {1473-7159},
	year = {2018},
	eissn = {1744-8352},
	pages = {587-589}
}