@article{MTMT:34036752, title = {Acetyl group for proper protection of β-sugar-amino acids used in SPPS}, url = {https://m2.mtmt.hu/api/publication/34036752}, author = {Varga, István and Goldschmidt Gőz, Viktória and Pintér, István and Csámpai, Antal and Perczel, András}, doi = {10.1007/s00726-023-03278-1}, journal-iso = {AMINO ACIDS}, journal = {AMINO ACIDS}, volume = {55}, unique-id = {34036752}, issn = {0939-4451}, abstract = {The synthesis of d- glucosamine-1-carboxylic acid based β-sugar amino acids (β-SAAs) is typically performed in nine consecutive steps via an inefficient OAc → Br → CN conversion protocol with low overall yield. Here, we present the improved and more efficient synthesis of both Fmoc-GlcAPC-OH and Fmoc-GlcAPC(Ac)-OH, β-SAAs consisting of only 4–5 synthetic steps. Their active ester and amide bond formation with glycine methyl ester (H-Gly-OMe) was completed and monitored by 1 H NMR. The stability of the pyranoid OHs protecting the acetyl groups was investigated under three different Fmoc cleavage conditions and was found to be satisfactory even at high piperidine concentration (e.g. 40%). We designed a SPPS protocol using Fmoc-GlcAPC(Ac)-OH to produce model peptides Gly-β-SAA-Gly as well as Gly-β-SAA-β-SAA-Gly with high coupling efficiency. The products were deacetylated using the Zemplén method, which allows the hydrophilicity of a building block and/or chimera to be fine-tuned, even after the polypeptide chain has already been synthesized.}, year = {2023}, eissn = {1438-2199}, pages = {969-979}, orcid-numbers = {Csámpai, Antal/0000-0003-2107-7309; Perczel, András/0000-0003-1252-6416} } @mastersthesis{MTMT:31598328, title = {Új β-cukoraminosavak előállítása és beépítése új típusú foldamerekbe}, url = {https://m2.mtmt.hu/api/publication/31598328}, author = {Goldschmidt Gőz, Viktória}, doi = {10.15476/ELTE.2019.225}, publisher = {Eötvös Loránd University}, unique-id = {31598328}, year = {2020} } @article{MTMT:30937506, title = {Assignment of Vibrational Circular Dichroism Cross-Referenced Electronic Circular Dichroism Spectra of Flexible Foldamer Building Blocks: Towards Assigning Pure Chiroptical Properties of Foldamers}, url = {https://m2.mtmt.hu/api/publication/30937506}, author = {Farkas, Viktor and Nagy, Adrienn and Karancsiné Menyhárd, Dóra and Perczel, András}, doi = {10.1002/chem.201903023}, journal-iso = {CHEM-EUR J}, journal = {CHEMISTRY-A EUROPEAN JOURNAL}, volume = {25}, unique-id = {30937506}, issn = {0947-6539}, year = {2019}, eissn = {1521-3765}, pages = {14890-14900}, orcid-numbers = {Farkas, Viktor/0000-0002-8815-2783; Karancsiné Menyhárd, Dóra/0000-0002-0095-5531; Perczel, András/0000-0003-1252-6416} } @article{MTMT:27524780, title = {Conformation Analysis of GalNAc-Appended Sugar Amino Acid Foldamers as Glycopeptide Mimics}, url = {https://m2.mtmt.hu/api/publication/27524780}, author = {Sunkari, Yashoda Krishna and Pulukuri, Kiran Kumar and Kandiyal, Pancham Singh and Vaishnav, Jayanti and Ampapathi, Ravi Sankar and Chakraborty, Tushar Kanti}, doi = {10.1002/cbic.201800087}, journal-iso = {CHEMBIOCHEM}, journal = {CHEMBIOCHEM}, volume = {19}, unique-id = {27524780}, issn = {1439-4227}, year = {2018}, eissn = {1439-7633}, pages = {1507-1513} } @article{MTMT:31848285, title = {Amino acids: Chemistry, diversity and physical properties}, url = {https://m2.mtmt.hu/api/publication/31848285}, author = {Zarándi, Márta and Szolomájer, János}, doi = {10.1039/9781788010627-00001}, journal-iso = {AMINO ACIDS PEPT PROTEIN}, journal = {AMINO ACIDS PEPTIDES AND PROTEINS}, volume = {42}, unique-id = {31848285}, issn = {1361-5904}, abstract = {The occurrence, chemistry, resolution, and analysis of amino acids published in the literature from 2013 finished with the year of 2016 are reviewed in this Chapter which is arranged in sections similar to previous Volumes in this Specialist Periodical report. Scientific Papers published during 2013-2016 have been sourced mainly from the Web of Science databases and Pubmed on the internet and from scanning a selection of major journals. © 2018 The Royal Society of Chemistry.}, year = {2018}, eissn = {1465-1912}, pages = {1-84}, orcid-numbers = {Zarándi, Márta/0000-0002-2136-2946; Szolomájer, János/0000-0003-1458-6156} }