TY - JOUR AU - Brunner, Szilvia AU - Tőkés, Tünde AU - Szabó, Emilia Rita AU - Polanek, Róbert AU - Szabó, Zoltán Imre AU - Reisz, Zita AU - Konczné Gubán, Barbara AU - Szijártó, András Lajos AU - Michael, Brand AU - Stefan, Hans AU - Leonhard, Karsch AU - Elisabeth, Lessmann AU - Jörg, Pawelke AU - Michael, Schürer AU - Elke, Beyreuther AU - Hideghéty, Katalin TI - Dose-dependent Changes After Proton and Photon Irradiation in a Zebrafish Model JF - ANTICANCER RESEARCH J2 - ANTICANCER RES VL - 40 PY - 2020 IS - 11 SP - 6123 EP - 6135 PG - 13 SN - 0250-7005 DO - 10.21873/anticanres.14633 UR - https://m2.mtmt.hu/api/publication/31655754 ID - 31655754 N1 - ELI-ALPS, ELI-HU Non-Profit Ltd., Szeged, Hungary Department of Pathology, University of Szeged, Szeged, Hungary Department of Clinical Neuropathology, King’s College Hospital, London, United Kingdom Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary Department of Medical Physics and Informatics, University of Szeged, Szeged, Hungary Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Dresden, Germany OncoRay – National Center for Radiation Research in Oncology, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany Helmholtz-Zentrum Dresden–Rossendorf, Dresden, Germany National Center for Tumor Diseases (NCT), Dresden, Germany Department of Oncotherapy, University of Szeged, Szeged, Hungary Export Date: 11 February 2022 CODEN: ANTRD Correspondence Address: Brunner, S.; ELI-ALPS, Wolfgang Sandner Str. 3., Hungary; email: Szilvia.Brunner@elialps.hu LA - English DB - MTMT ER - TY - JOUR AU - Hideghéty, Katalin AU - Brunner, Szilvia AU - Cheesman, Andrew AU - Szabó, Emilia Rita AU - Polanek, Róbert AU - Margarone, Daniele AU - Tőkés, Tünde AU - Mogyorósi, Károly TI - 11 Boron Delivery Agents for Boron Proton-capture Enhanced Proton Therapy JF - ANTICANCER RESEARCH J2 - ANTICANCER RES VL - 39 PY - 2019 IS - 5 SP - 2265 EP - 2276 PG - 12 SN - 0250-7005 DO - 10.21873/anticanres.13343 UR - https://m2.mtmt.hu/api/publication/30732651 ID - 30732651 N1 - University of Szeged, Faculty of Medicine, Department of Oncotherapy, Szeged, Hungary ELI-Beamlines, Institute of Physics of the Czech Academy of Sciences, Prague, Czech Republic ELI-ALPS, ELI-HU NonProfit Ltd, Wolfgang Sandner Str. 3, Szeged, 6728, Hungary Cited By :9 Export Date: 11 May 2022 CODEN: ANTRD Correspondence Address: Brunner, S.; ELI-ALPS, Wolfgang Sandner Str. 3, Hungary; email: Szilvia.Brunner@eli-alps.hu LA - English DB - MTMT ER - TY - JOUR AU - Khan, Muhammad Isa AU - Shakil, Muhammad AU - Tahir, Muhammad Bilal AU - Rafique, Muhammad AU - Iqbal, Tahir AU - Zahoor, Aliza AU - Rehman, Jalil Ur AU - Iqbal, Khalid AU - Chow, James C. L. TI - Selection of gamma analysis acceptance criteria in IMRT QA using Gafchromic EBT3 film dosimetry JF - JOURNAL OF RADIOTHERAPY IN PRACTICE J2 - J RADIOTHER PRACT VL - 18 PY - 2019 IS - 2 SP - 127 EP - 131 PG - 5 SN - 1460-3969 DO - 10.1017/S1460396918000602 UR - https://m2.mtmt.hu/api/publication/30913045 ID - 30913045 N1 - Department of Physics, University of Gujarat, Gujarat, Pakistan Department of Physics, BUITEMS, Quetta, Pakistan Department of Radiation Oncology, Shaukat Khanum Cancer Hospital and Research Center, Lahore, Pakistan Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, 700 University Avenue, Toronto, ON M5G 1Z5, Canada Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada Cited By :1 Export Date: 11 May 2022 CODEN: JRPOA Correspondence Address: Chow, J.C.L.; Radiation Medicine Program, 700 University Avenue, Canada; email: james.chow@rmp.uhn.ca AB - Background and purpose This study reported the justification and selection of acceptable gamma criteria with respect to low (6 MV) and high (15 MV) photon beams for intensity-modulated radiation therapy quality assurance (IMRT QA) using the Gafchromic external beam therapy 3 (EBT3) film. Materials and methods Five-field step-and-shoot IMRT was used to treat 16 brain IMRT patients using the dual-energy DHX-S linear accelerator (Varian Medical System, Palo Alto, CA, USA). Dose comparisons between computed values of the treatment planning system (TPS) and Gafchromic EBT3 film were evaluated based on gamma analysis using the Film QA Pro software. The dose distribution was analysed with gamma area histograms (GAHs) generated using different gamma criteria (3%/2 mm, 3%/3 mm and 5%/3 mm) for the 6 and 15 MV photon beams, to optimise the best distance-to-agreement (DTA) criteria with respect to the beam energy. Results From the comparison between the dose distributions acquired from the TPS and EBT3 film, a DTA criterion of 3%/2 mm showed less dose differences (DDs) with passing rates up to 93% for the 6 MV photon beams, while for the 15 MV a relaxed DTA criterion of 5%/3 mm was consistent with the DD acceptability criteria with a 95% passing rate. Conclusions Our results suggested that high-energy photon beams required relaxed DTA criteria for the brain IMRT QA, while low-energy photon beams showed better results even with tight DTA criteria. LA - English DB - MTMT ER - TY - JOUR AU - Scuderi, Valentina AU - Amato, Antonino AU - Amico, Antonio Giuseppe AU - Borghesi, Marco AU - Cirrone, Giuseppe Antonio Pablo AU - Cuttone, Giacomo AU - Fajstavr, Antonin AU - Giuffrida, Lorenzo AU - Grepl, Filip AU - Korn, Georg AU - Larosa, Giuseppina AU - Leanza, Renata AU - Margarone, Daniele AU - Milluzzo, Giuliana AU - Petringa, Giada AU - Pipek, Jan AU - Russo, Antonio AU - Schillaci, Francesco AU - Velyhan, Andriy AU - Romano, Francesco TI - Diagnostics and Dosimetry Solutions for Multidisciplinary Applications at the ELIMAIA Beamline JF - APPLIED SCIENCES-BASEL J2 - APPL SCI-BASEL VL - 8 PY - 2018 IS - 9 PG - 21 SN - 2076-3417 DO - 10.3390/app8091415 UR - https://m2.mtmt.hu/api/publication/30518757 ID - 30518757 N1 - Institute of Physics ASCR, v.v.i. (FZU), ELI-Beamlines Project, Prague, 18221, Czech Republic Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud, Catania, 95123, Italy Centre for Plasma Physics, School of Mathematics and Physics, Queen's University Belfast, Belfast, BT7 1NN, United Kingdom National Physical Laboratory, CMES Medical Radiation Science, Teddington, TW110LW, United Kingdom Cited By :8 Export Date: 11 May 2022 Correspondence Address: Scuderi, V.; Institute of Physics ASCR, Czech Republic; email: valentina.scuderi@eli-beams.eu AB - ELI (Extreme Light Infrastructure) multidisciplinary applications of laser-ion acceleration (ELIMAIA) is one the user facilities beamlines of the ELI-Beamlines facility in Prague. It will be dedicated to the transport of laser-driven ion beams and equipped with detectors for diagnostics and dosimetry, in order to carry out experiments for a broad range of multidisciplinary applications. One of the aims of the beamline is also to demonstrate the feasibility of these peculiar beams for possible medical applications, which means delivering controllable and stable beams, properly monitoring their transport parameters and accurately measuring the dose per shot. To fulfil this task, innovative systems of charged particle beam diagnostics have been realized and alternative approaches for relative and absolute dosimetry have been proposed. Concerning the first one, real-time diagnostic solutions have been adopted, involving the use of time-of-flight techniques and Thomson parabola spectrometry for an on-line characterization of the ion beam parameters, as well as radiochromic films, nuclear track detectors (typically CR39), and image plates for single shot measurements. For beam dosimetry, real-time beam/dose monitoring detectors have been realized, like the secondary emission monitor and a double-gap ionization chamber, which can be cross calibrated against a Faraday cup, used for absolute dosimetry. The main features of these detectors are reported in this work together with a description of their working principle and some preliminary tests. LA - English DB - MTMT ER -