TY - JOUR AU - Andréka, Lilla AU - Csenteri, Orsolya AU - Andréka, Péter AU - Vajer, Péter TI - Egészségi állapot és cardiovascularis kockázat roma és nem roma populációban hátrányos helyzetű településeken JF - ORVOSI HETILAP J2 - ORV HETIL VL - 164 PY - 2023 IS - 20 SP - 792 EP - 799 PG - 8 SN - 0030-6002 DO - 10.1556/650.2023.32747 UR - https://m2.mtmt.hu/api/publication/33862703 ID - 33862703 AB - Bevezetés: A „Helybe visszük a szűrővizsgálatokat” programban hátrányos helyzetű települések lakosainak elsősorban szív- és érrendszeri szűrése zajlik. Célkitűzés: A hátrányos helyzetű településeken élő roma és nem roma lakosság egészségi állapotának, kockázatainak elemzése. Módszer: A szűrésen demográfiai, életmódra, fennálló betegségekre, egészségügyi ellátáshoz való hozzáférésre és a betegtájékoztatás minőségére vonatkozó adatokat rögzítettek. Általános állapotfelmérésre (testtömeg-, testmagasság-, vérnyomás-, vércukorszint- és boka-kar index mérés), szakorvosi vizsgálatra került sor. Az adatok elemzése roma és nem roma bontásban történt, Pearson-féle khi-négyzet-próba segítségével. Eredmények: A vizsgálatban 3649 fő (851 [23%] férfi, 2798 [77%] nő) vett részt, közülük 16% (598) roma nemzetiségű. Az átlagéletkor férfiaknál 58, nőknél 55, a roma populációban férfiaknál 48, nőknél 47 év. A roma férfiak 45%-a, a roma nők 64%-a, az átlagpopulációban mindkét nem 30%-a dohányzik. A romák között a cukros üdítőitalok heti minimum négyszeri fogyasztása (férfiak 55%, nők 43%) és a BMI (férfiak 30 vs. 29, nők 29 vs. 28) szignifikánsan nagyobb a nem roma populációénál. A roma férfiak 31%-a, a roma nők 13%-a, az átlagpopulációban a férfiak 17%-a, a nők 8%-a ítéli rossznak egészségi állapotát. A COPD (18% vs. 9%), a coronariabetegség (18% vs. 13%), illetve a perifériás verőérbetegség (13% vs. 9%) előfordulása szignifikánsan gyakoribb a roma nők esetében, mint a nem romáknál. Következtetés: A vizsgált populációban a roma lakosság szignifikánsan fiatalabb korosztály, többet dohányzik, elhízottabb, gyakrabban fordulnak elő körükben a krónikus, nem fertőző betegségek, és rosszabbnak tartják az egészségi állapotukat. Orv Hetil. 2023; 164(20): 792–799. LA - Hungarian DB - MTMT ER - TY - JOUR AU - Kolossváry, Endre AU - Farkas, Katalin AU - Karahan, Oguz AU - Golledge, Jonathan AU - Schernthaner, Gerit-Holger AU - Karplus, Thomas AU - Bernardo, Jonathan James AU - Marschang, Sascha AU - Abola, Maria Teresa AU - Heinzmann, Monica AU - Edmonds, Michael AU - Catalano, Mariella TI - The importance of socio-economic determinants of health in the care of patients with peripheral artery disease: A narrative review from VAS JF - VASCULAR MEDICINE J2 - VASC MED VL - 28 PY - 2023 IS - 3 SP - 241 EP - 253 PG - 13 SN - 1358-863X DO - 10.1177/1358863X231169316 UR - https://m2.mtmt.hu/api/publication/33809654 ID - 33809654 N1 - VAS-European Independent Foundation in Angiology/Vascular Medicine, Italy VAS-International Consortium – International PAD Strategic Network, Italy Inter-University Research Center on Vascular Disease, Department Biomedical and Clinical Science, University of Milan, Milan, Italy Department of Angiology, St Imre University Teaching Hospital, Budapest, Hungary Department of Cardiovascular Surgery, Medical School of Alaaddin Keykubat University, Alanya/Antalya, Diyarbakir, Turkey James Cook University, Townsville University Hospital, Townsville, QLD, Australia Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria Department of Vascular Medicine, Concord Repatriation General Hospital, Sydney, NSW, Australia Department of Vascular Medicine, St Luke’s Medical Center, NCR, Quezon, Philippines Department Managing Committee, VAS-European Independent Foundation in Angiology/Vascular Medicine, Bruxelles, Belgium University of the Philippines College of Medicine–Philippine, Philippine Heart Center, Quezon, Philippines Angiology Unit, Allende Sanatorium, Nueva, Cordóba, Argentina King’s College Hospital, Diabetic Foot Clinic, London, United Kingdom Department of Biomedical and Clinical Sciences L Sacco Hospital, Inter-University Research Center on Vascular Disease, University of Milan, Milan, Italy Cited By :1 Export Date: 16 August 2023 CODEN: VAMLF Correspondence Address: Kolossváry, E.; VAS-European Independent Foundation in Angiology/Vascular MedicineItaly; email: kolossendre@gmail.com AB - Socio-economic determinants of health (SDoH) include various nonmedical factors in the socio-economic sphere with a potentially significant impact on health outcomes. Their effects manifest through several mediators/moderators (behavioral characteristics, physical environment, psychosocial circumstances, access to care, and biological factors). Various critical covariates (age, gender/sex, race/ethnicity, culture/acculturation, and disability status) also interact. Analyzing the effects of these factors is challenging due to their enormous complexity. Although the significance of SDoH for cardiovascular diseases is well documented, research regarding their impact on peripheral artery disease (PAD) occurrence and care is less well documented. This narrative review explores to what extent SDoH are multifaceted in PAD and how they are associated with its occurrence and care. Additionally, methodological issues that may hamper this effort are addressed. Finally, the most important question, whether this association may contribute to reasonable interventions aimed at SDoH, is analyzed. This endeavor requires attention to the social context, a whole systems approach, multilevel-thinking, and a broader alliance that reaches out to more stakeholders outside the medical sphere. More research is needed to justify the power in this concept to improve PAD-related outcomes like lower-extremity amputations. At the present time, some evidence, reasonable consideration, and intuitive reasoning support the implementation of various interventions in SDoH in this field. LA - English DB - MTMT ER - TY - JOUR AU - Pikó, Péter AU - Bácsné Bába, Éva AU - Kósa, Zsigmond AU - Sándor, János AU - Kovács, Nóra AU - Bács, Zoltán AU - Ádány, Róza TI - Genetic Determinants of Leisure-Time Physical Activity in the Hungarian General and Roma Populations JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 24 PY - 2023 IS - 5 PG - 14 SN - 1661-6596 DO - 10.3390/ijms24054566 UR - https://m2.mtmt.hu/api/publication/33679402 ID - 33679402 AB - Leisure-time physical activity (LTPA) is one of the modifiable lifestyle factors that play an important role in the prevention of non-communicable (especially cardiovascular) diseases. Certain genetic factors predisposing to LTPA have been previously described, but their effects and applicability on different ethnicities are unknown. Our present study aims to investigate the genetic background of LTPA using seven single nucleotide polymorphisms (SNPs) in a sample of 330 individuals from the Hungarian general (HG) and 314 from the Roma population. The LTPA in general and three intensity categories of it (vigorous, moderate, and walking) were examined as binary outcome variables. Allele frequencies were determined, individual correlations of SNPs to LTPA, in general, were determined, and an optimized polygenetic score (oPGS) was created. Our results showed that the allele frequencies of four SNPs differed significantly between the two study groups. The C allele of rs10887741 showed a significant positive correlation with LTPA in general (OR = 1.48, 95% CI: 1.12–1.97; p = 0.006). Three SNPs (rs10887741, rs6022999, and rs7023003) were identified by the process of PGS optimization, whose cumulative effect shows a strong significant positive association with LTPA in general (OR = 1.40, 95% CI: 1.16–1.70; p < 0.001). The oPGS showed a significantly lower value in the Roma population compared with the HG population (oPGSRoma: 2.19 ± SD: 0.99 vs. oPGSHG: 2.70 ± SD: 1.06; p < 0.001). In conclusion, the coexistence of genetic factors that encourage leisure-time physical activity shows a more unfavorable picture among Roma, which may indirectly contribute to their poor health status. LA - English DB - MTMT ER - TY - JOUR AU - Anastasaki, Marilena AU - van Bree, Egid M. AU - Brakema, Evelyn A. AU - Tsiligianni, Ioanna AU - Sifaki-Pistolla, Dimitra AU - Chatzea, Vasiliki E. AU - Crone, Matty C. AU - Karelis, Andreas AU - van der Kleij, Rianne M. J. J. AU - Poot, Charlotte C. AU - Reis, Ria AU - Chavannes, Niels H. AU - Lionis, Christos TI - Beliefs, Perceptions, and Behaviors Regarding Chronic Respiratory Diseases of Roma in Crete, Greece: A Qualitative FRESH AIR Study JF - FRONTIERS IN PUBLIC HEALTH J2 - FRONT PUBLIC HEALTH VL - 10 PY - 2022 PG - 12 SN - 2296-2565 DO - 10.3389/fpubh.2022.812700 UR - https://m2.mtmt.hu/api/publication/32788562 ID - 32788562 N1 - Clinic of Social and Family Medicine, School of Medicine, University of Crete, Heraklion, Greece Department of Public Health and Primary Care, Leiden University Medical Centre, Leiden, Netherlands Export Date: 24 July 2022 Correspondence Address: Anastasaki, M.; Clinic of Social and Family Medicine, Greece; email: anastasakimarilena@yahoo.gr LA - English DB - MTMT ER - TY - JOUR AU - Pikó, Péter AU - Werissa, Nardos Abebe AU - Ádány, Róza TI - Genetic Susceptibility to Insulin Resistance and Its Association with Estimated Longevity in the Hungarian General and Roma Populations JF - BIOMEDICINES J2 - BIOMEDICINES VL - 10 PY - 2022 IS - 7 PG - 18 SN - 2227-9059 DO - 10.3390/biomedicines10071703 UR - https://m2.mtmt.hu/api/publication/33059861 ID - 33059861 N1 - Export Date: 13 August 2023 Correspondence Address: Adany, R.; ELKH-DE Public Health Research Group, Hungary; email: adany.roza@med.unideb.hu AB - Diabetes mellitus is a major public health problem with a wide range of prevalence among different ethnic groups. Early recognition of pre-diabetes is important to prevent the development of the disease, its complications, co-morbidities, and consequently early death. Insulin resistance (IR) is considered a condition that precedes type 2 diabetes; thus, understanding its underlying causes (genetic and non-genetic factors) will bring us closer to preventing it. The present study aimed to investigate the genetic susceptibility to IR and its impact on estimated longevity in populations with different ethnic origins using randomly selected samples of 372 Hungarian general (HG, as a reference with Caucasian origin) and 334 Roma participants (largest ethnic minority in Europe, with a northern India origin). In the present study, we used the Homeostasis Model Assessment—Insulin Resistance (HOMA—IR) to identify people with IR (>3.63) at the population level. To investigate the genetic predisposition to IR, 29 single nucleotide polymorphisms (SNPs) identified in a systematic literature search were selected and genotyped in sample populations. In the analyses, the adjusted p < 0.0033 was considered significant. Of these 29 SNPs, the commutative effects of 15 SNPs showing the strongest association with HOMA—IR were used to calculate an optimized genetic risk score (oGRS). The oGRS was found nominally significantly (p = 0.019) higher in the Roma population compared to HG one, and it was more strongly correlated with HOMA—IR. Therefore, it can be considered as a stronger predictor of the presence of IR among the Roma (AUCRoma = 0.673 vs. AUCHG = 0.528). Furthermore, oGRS also showed a significant correlation with reduced estimated longevity in the Roma population (β = −0.724, 95% CI: −1.230–−0.218; p = 0.005), but not in the HG one (β = 0.065, 95% CI: −0.388–0.518; p = 0.779). Overall, IR shows a strong correlation with a genetic predisposition among Roma, but not in the HG population. Furthermore, the increased genetic risk of Roma is associated with shorter estimated longevity, whereas this association is not observed in the HG one. Increased genetic susceptibility of Roma to IR should be considered in preventive programs targeting the development of type 2 diabetes, which may also reduce the risk of preventable premature death among them. LA - English DB - MTMT ER - TY - THES AU - Erand, Llanaj TI - Nutrition and dietary profile of the Roma population living in segregated colonies PY - 2021 SP - 97 UR - https://m2.mtmt.hu/api/publication/32186922 ID - 32186922 LA - English DB - MTMT ER - TY - JOUR AU - Zajc Petranovic, Matea AU - Rizzieri, Ashley Elizabeth AU - Sivaraj, Dharshan AU - Smolej Narancic, Nina AU - Skaric-Juric, Tatjana AU - Celinscak, Zeljka AU - Stojanovic Markovic, Anita AU - Pericic Salihovic, Marijana AU - Kalaszi, Julia AU - Kalaszi, Marianna AU - Lin, John Q. AU - Mehta, Sanica AU - Burleson, Jill AU - Rizzieri, David A. TI - CVD Risk Factors in the Ukrainian Roma and Meta-Analysis of Their Prevalence in Roma Populations Worldwide JF - JOURNAL OF PERSONALIZED MEDICINE J2 - J PERS MED VL - 11 PY - 2021 IS - 11 PG - 23 SN - 2075-4426 DO - 10.3390/jpm11111138 UR - https://m2.mtmt.hu/api/publication/32728040 ID - 32728040 N1 - Institute for Anthropological Research, Gajeva 32, Zagreb, 10000, Croatia Division of Cellular Therapy, Duke University, 2400 Pratt Street, Durham, NC 27708, United States School of Medicine, Stanford University, 291 Campus Drive, Stanford, CA 94305, United States Cited By :1 Export Date: 12 June 2022 Correspondence Address: Petranović, M.Z.; Institute for Anthropological Research, Gajeva 32, Croatia; email: matea@inantro.hr Correspondence Address: Rizzieri, D.A.; Division of Cellular Therapy, 2400 Pratt Street, United States; email: david.rizzieri@dm.duke.edu AB - The Roma population suffers from severe poverty, social exclusion, and some of the worst health conditions in the industrialized world. Herein, we report on cardiovascular disease (CVD) risk factors in the Ukrainian Roma and present a meta-analysis of the prevalence of CVD risk factors in 16 Roma populations worldwide. The meta-analyses of CVD risk factors in Roma (n = 16,552) vs. non-Roma majority population of the same country (n = 127,874) included publicly available data. Ukrainian field survey included 339 adults of both sexes and outcomes of interest were hypertension, body mass index (BMI), smoking, education, and employment status. Furthermore, 35.7% of the Ukrainian Roma were hypertensive, 69.3% unemployed, and 48.4% never went to school. Ukrainian Roma women were more likely to be underweight and more prone to be hypertensive, with odds of hypertension increasing with age, BMI, and positive smoking status. Meta-analyses showed that, in comparison with non-Roma worldwide, the Roma bear significantly higher risk factor loads related to smoking (OR = 2.850), diabetes (OR = 1.433), abdominal obesity (OR = 1.276), and metabolic syndrome (OR = 1.975), with lower loads for hypertension (OR = 0.607) and BMI & GE; 25 kg/m(2) (OR = 0.872). To conclude, the CVD risk factors which are more common in Roma than in the majority population may reflect their poor health-related behaviors and inadequate access to health education. LA - English DB - MTMT ER -