@article{MTMT:35202794, title = {Occurrence of the two major regulated mycotoxins, ochratoxin A and fumonisin B1, in cereal and cereal-based products in Europe and toxicological effects: A review}, url = {https://m2.mtmt.hu/api/publication/35202794}, author = {Arce-Lopez, Beatriz and Coton, Monika and Coton, Emmanuel and Hymery, Nolwenn}, doi = {10.1016/j.etap.2024.104489}, journal-iso = {ENVIRON TOXICOL PHAR}, journal = {ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY}, volume = {109}, unique-id = {35202794}, issn = {1382-6689}, abstract = {Among cereal contaminants, mycotoxins are of concern due to their importance in terms of food and feed safety. The difficulty in establishing a diagnosis for mycotoxicosis relies on the fact that the effects are most often subclinical for chronic exposure and the most common scenario is multi -contamination by various toxins. Mycotoxin co -occurrence is a major food safety concern as additive or even synergic toxic impacts may occur, but also regarding current regulations as they mainly concern individual mycotoxin levels in specific foods and feed in the food chain. However, due to the large number of possible mycotoxin combinations, there is still limited knowledge on co -exposure toxicity data, which depends on several parameters. In this context, this systematic review aims to provide an overview of the toxic effects of two regulated mycotoxins, namely ochratoxin A and fumonisin B1. This review focused on the 2012 -2022 period and analysed the occurrence in Europe of the selected mycotoxins in different food matrices (cereals and cereal -derived products), and their toxic impact, alone or in combination, on i n vitro intestinal and hepatic human cells. To better understand and evaluate the associated risks, further research is needed using new approach methodologies (NAM), such as in vitro 3D models. Key contribution: Cereals and their derived products are the most important food source for humans and feed for animals worldwide. This manuscript is a state of the art review of the literature over the last ten years on ochratoxin A and fumonisin B1 mycotoxins in these products in Europe as well as their toxicological effects, alone and in combination, on human cells. Future perspectives and some challenges regarding the assessment of toxicological effects of mycotoxins are also discussed.}, keywords = {IN-VITRO; GENE-EXPRESSION; Occurrence; MYCOTOXINS; RISK-ASSESSMENT; dried blood spots; food safety; EXPOSURE ASSESSMENT; gluten-free; Dietary exposure; Pharmacology & Pharmacy; Environmental Sciences; Combined effects; Breakfast cereals; toxicology in vitro; MULTIPLE MYCOTOXINS}, year = {2024}, eissn = {1872-7077} } @article{MTMT:35827813, title = {Toward advanced analytical procedures for detecting Fumonisins in contaminated food and feed using molecularly imprinted polymers: A mini review}, url = {https://m2.mtmt.hu/api/publication/35827813}, author = {Diab, M. A. and El-Sabban, Heba A. and Baek, Kwang-Hyun}, doi = {10.1016/j.microc.2024.111858}, journal-iso = {MICROCHEM J}, journal = {MICROCHEMICAL JOURNAL}, volume = {207}, unique-id = {35827813}, issn = {0026-265X}, keywords = {solid phase extraction; molecularly imprinted polymer; Fumonisins; Monolithic MIPs; Multi-template MIPs; Epitope imprinting polymers}, year = {2024}, eissn = {1095-9149} } @article{MTMT:34942477, title = {Analysis of Mycotoxins and Cytotoxicity of Airborne Molds Isolated from the Zoological Garden-Screening Research}, url = {https://m2.mtmt.hu/api/publication/34942477}, author = {Plewa-Tutaj, Kinga and Twaruzek, Magdalena and Kosicki, Robert and Soszczynska, Ewelina}, doi = {10.3390/pathogens13040294}, journal-iso = {PATHOGENS}, journal = {PATHOGENS}, volume = {13}, unique-id = {34942477}, keywords = {HPLC; MYCOTOXINS; MTT assay}, year = {2024}, eissn = {2076-0817}, orcid-numbers = {Plewa-Tutaj, Kinga/0000-0002-0126-6287} } @article{MTMT:34978982, title = {The effects of the extrusion process used for the production of maize snacks and pasta on the free, bound, and total B fumonisin contents}, url = {https://m2.mtmt.hu/api/publication/34978982}, author = {Scarpino, Valentina and Bresciani, Andrea and Blandino, Massimo}, doi = {10.1016/j.lwt.2024.115977}, journal-iso = {LWT-FOOD SCI TECHNOL}, journal = {LWT-FOOD SCIENCE AND TECHNOLOGY}, volume = {198}, unique-id = {34978982}, issn = {0023-6438}, keywords = {corn flour; Hidden fumonisins; Break meal; Gluten -free; Hydrolized fumonisins}, year = {2024}, eissn = {1096-1127}, orcid-numbers = {Blandino, Massimo/0000-0003-3719-2520} } @article{MTMT:34331633, title = {Chronic oral exposure to low-concentration fumonisin B2 significantly exacerbates the inflammatory responses of allergies in mice via inhibition of IL-10 release by regulatory T cells in gut-associated lymphoid tissue}, url = {https://m2.mtmt.hu/api/publication/34331633}, author = {Ando, Mana and Yamaguchi, Hiroki and Morimoto, Ai and Iwashita, Naoki and Takagi, Yoshiichi and Nagane, Masaki and Yoshinari, Tomoya and Fukuyama, Tomoki}, doi = {10.1007/s00204-023-03579-0}, journal-iso = {ARCH TOXICOL}, journal = {ARCHIVES OF TOXICOLOGY}, volume = {97}, unique-id = {34331633}, issn = {0340-5761}, abstract = {Contamination with fumonisins produced by Fusarium spp. is rapidly growing in both developing and developed countries. The purpose of this study was to determine whether oral exposure to fumonisin contributed to the development of allergic diseases. We initially examined the immunotoxic potential of short-term, oral administration of fumonisin B1 (FB1, 1 mg/kg) and fumonisin B2 (FB2, 1 mg/kg), both naturally occurring fumonisins, using a BALB/c mouse model of allergic contact dermatitis and Dermatophagoides farina-induced asthma. Using an NC/nga mouse model of atopic dermatitis (AD), we evaluated the adverse effects of subchronic oral exposure to low concentrations of FB2 (2 or 200 & mu;g/kg). Finally, we explored the influence of FB2 on regulatory T cell proliferation and function in mesenteric lymph nodes after 1-week oral exposure to FB2 in BALB/c mice. Oral exposure to FB2 markedly exacerbated the symptoms of allergy, including skin thickness, histological evaluation, immunocyte proliferation, and proinflammatory cytokine production, although no change was observed following exposure to FB1. Furthermore, oral exposure to low concentrations of FB2 considerably exacerbated the AD scores, skin thickness, transepidermal water loss, histological features, and proinflammatory cytokine production. The aggravated allergic symptoms induced by oral exposure to FB2 could be attributed to the direct inhibition of IL-10 production by regulatory T cells in mesenteric lymph nodes. Our findings indicate that the recommended maximum fumonisin level should be reconsidered based on the potential for allergy development.}, keywords = {Asthma; IL-10; Regulatory T cell; Atopic dermatitis; fumonisin B2}, year = {2023}, eissn = {1432-0738}, pages = {2707-2719}, orcid-numbers = {Nagane, Masaki/0000-0002-3408-7656; Fukuyama, Tomoki/0000-0003-3510-3272} } @article{MTMT:34331634, title = {Promising bioactive metabolites of mangrove inhabitant Streptomyces tauricus and prostate cancer PC3 cell inhibition by antimicrobial peptides}, url = {https://m2.mtmt.hu/api/publication/34331634}, author = {Karthik, Yalpi and Kalyani, Manjula Ishwara and Krishnappa, Srinivasa and Ramakrishna, Krishnaveni and Sayed, Samy M. and Aharthy, Ohud Muslat and Alhelaify, Seham Sater and Mushtaq, Muntazir}, doi = {10.3389/fmicb.2023.1152985}, journal-iso = {FRONT MICROBIOL}, journal = {FRONTIERS IN MICROBIOLOGY}, volume = {14}, unique-id = {34331634}, abstract = {Streptomyces is a group of microbes known for antibiotic production and has contributed to more than 70% of present commercially available antibiotics. These antibiotics are important in the management, protection, and treatment of chronic illnesses. In the present study, the isolated S. tauricus strain from mangrove soil in Mangalore, India (GenBank accession number: MW785875) was subjected for differential cultural characterization, phenotype involving brown pigmentation, filamentous mycelia, and ash-colored spore production was observed using field emission scanning electron microscopy (FESEM) analysis revealing filamentous mycelia possessing a straight spore chain. Spores were visualized as elongated, rod-shaped, smooth surfaces with curved edges. After optimized growth conditions for S. tauricus on starch-casein agar medium, the GC/MS analysis of S. tauricus intracellular extract detected bioactive compounds reported for pharmacological applications. Analyzed using the NIST library, most of the bioactive compounds identified in intracellular extract had molecular weights of less than 1 kDa. On the PC3 cell line, the Sephadex G-10 partially purified eluted peak protein fraction demonstrated significant anticancer activity. The LCMS analysis revealed the presence of Tryprostatin B, Fumonisin B1, Microcystin LR, and Surfactin C with molecular weights below 1 kDa. This study found that small molecular weight microbial compounds are more effective in a variety of biological applications.}, keywords = {CHROMATOGRAPHY; Anticancer; mangroves; FESEM; Streptomyces tauricus}, year = {2023}, eissn = {1664-302X} } @article{MTMT:33926742, title = {Bacteriological Quality and Biotoxin Profile of Ready-to-Eat Foods Vended in Lagos, Nigeria}, url = {https://m2.mtmt.hu/api/publication/33926742}, author = {Makinde, O.M. and Sulyok, M. and Adeleke, R.A. and Krska, R. and Ezekiel, C.N.}, doi = {10.3390/foods12061224}, journal-iso = {FOODS}, journal = {FOODS}, volume = {12}, unique-id = {33926742}, issn = {2304-8158}, keywords = {Fumonisin; food safety; aflatoxin; Food contaminants; Plant toxins; foodborne bacteria; aadun; eko; kokoro; phytoestrogenic phenols}, year = {2023}, eissn = {2304-8158} } @article{MTMT:33926743, title = {The association of food ingredients in breakfast cereal products and fumonisins production: risks identification and predictions}, url = {https://m2.mtmt.hu/api/publication/33926743}, author = {Purchase, J. and Donato, R. and Sacco, C. and Pettini, L. and Rookmin, A.D. and Melani, S. and Artese, A. and Purchase, D. and Marvasi, M.}, doi = {10.1007/s12550-023-00483-5}, journal-iso = {MYCOTOX RES}, journal = {MYCOTOXIN RESEARCH}, unique-id = {33926743}, issn = {0178-7888}, keywords = {CEREALS; Fusarium; MYCOTOXINS; FLOUR; Fumonisins; Decision model}, year = {2023}, eissn = {1867-1632} } @article{MTMT:33702477, title = {Mycotoxins occurrence in milk and cereals in North African countries–a review}, url = {https://m2.mtmt.hu/api/publication/33702477}, author = {Ben, Hassouna K. and Ben, Salah-Abbès J. and Chaieb, K. and Abbès, S.}, doi = {10.1080/10408444.2022.2157703}, journal-iso = {CRIT REV TOXICOL}, journal = {CRITICAL REVIEWS IN TOXICOLOGY}, volume = {52}, unique-id = {33702477}, issn = {1040-8444}, keywords = {CEREALS; milk; CONTAMINATION; MYCOTOXINS; detoxification; legislation}, year = {2022}, eissn = {1547-6898}, pages = {619-635} } @article{MTMT:33440314, title = {Harvest and post-harvest handling practices associated with fumonisin B-1 contamination in maize (Zea mays L.): dietary exposure and risk characterization in eastern Ethiopia}, url = {https://m2.mtmt.hu/api/publication/33440314}, author = {Mohammed, Abdi and Seid, Awol and Terefe, Habtamu and Cervini, Carla and Verheecke-Vaessen, Carol}, doi = {10.1007/s12550-022-00468-w}, journal-iso = {MYCOTOX RES}, journal = {MYCOTOXIN RESEARCH}, volume = {38}, unique-id = {33440314}, issn = {0178-7888}, abstract = {Maize is the main staple food crop in the eastern part of Ethiopia. However, maize loss is a major issue due to fungal contamination especially at the post-harvest stage owing to inadequate handling practices. This study aimed to assess post-harvest handling and awareness against fungal development and fumonisin B-1 (FB1) in maize and to calculate risk exposures of FB1. A total of 197 maize samples (grain and flour) were collected from five districts (Haramaya, Kersa, Meta, Oda Bultum, and Tullo). FB1 was detected using LC-MS/MS qTRAP. Exposure assessment was done based on the maize consumption rate per day in Ethiopia for different age groups (infants, children, and adults). Risk characterization depends on the margin of exposure (MoE) combined with the lower confidence limit of the benchmark dose level (BMDL). About 81% of farmers were not physically separating undamaged maize ears with damaged from either birds or fungi. Moreover, 100% were not using improved storage material. In storage samples, FB1 was detected as high as 1058 mu g/kg +/- 234 in the Kersa district while a minimum of 22.60 mu g/kg +/- 5.27 in Meta. In flour samples, the maximum FB1 (327 mu g/kg) was detected from the Oda Bultum district. The maximum exposure of infants was estimated at Kersa (1131 mu g/kg bw/day), followed by Oda Bultum (1073 mu g/kg bw/day) and Haramaya (854 mu g/kg bw/day). Overall, FB1 exposures ranged from 6.09 to 1131 mu g/kg bw/day, which is 3 to 500 mu g/kg bw/day higher than the maximum tolerable daily intake of 2 mu g/kg bw/day recommended by the World Health Organization. The MoE ranged from 0.15 to 176, with infants being at higher risk than adults. The study highlights the urgent need to enhance growers' awareness and knowledge of good post-harvest practices to reduce mycotoxin contamination in maize. Further biomarker analysis must be pursued to determine the risk exposure assessment for different age groups in these areas with a priority for the Kersa district.}, keywords = {MAIZE; EXPOSURE ASSESSMENT; FUMONISIN CONTAMINATION; Ethiopia; Post-harvest handling; Awareness assessment}, year = {2022}, eissn = {1867-1632}, pages = {275-287} } @article{MTMT:33127821, title = {Toxicity and preventive approaches of Fusarium derived mycotoxins using lactic acid bacteria: state of the art}, url = {https://m2.mtmt.hu/api/publication/33127821}, author = {Navale, Vishwambar D. and Vamkudoth, KoteswaraRao}, doi = {10.1007/s10529-022-03293-4}, journal-iso = {BIOTECHNOL LETT}, journal = {BIOTECHNOLOGY LETTERS}, volume = {44}, unique-id = {33127821}, issn = {0141-5492}, year = {2022}, eissn = {1573-6776}, pages = {1111-1126}, orcid-numbers = {Vamkudoth, KoteswaraRao/0000-0002-3131-0015} } @article{MTMT:32789422, title = {First Report of Fusarium andiyazi Presence in Portuguese Maize Kernels}, url = {https://m2.mtmt.hu/api/publication/32789422}, author = {Simões, D. and Diogo, E. and de, Andrade E.}, doi = {10.3390/agriculture12030336}, journal-iso = {AGRICULTURE-BASEL}, journal = {AGRICULTURE-BASEL}, volume = {12}, unique-id = {32789422}, keywords = {Portugal; MYCOTOXINS; ZEA MAYS; Fusarium spp}, year = {2022}, eissn = {2077-0472} } @article{MTMT:32324158, title = {Occurrence of Fusarium spp. in Maize Grain Harvested in Portugal and Accumulation of Related Mycotoxins during Storage}, url = {https://m2.mtmt.hu/api/publication/32324158}, author = {Carbas, Bruna and Simoes, Daniela and Soares, Andreia and Freitas, Andreia and Ferreira, Bruno and Carvalho, Alexandre R. E. and Silva, Ana Sanches and Pinto, Tiago and Diogo, Eugenio and Andrade, Eugenia and Brites, Carla}, doi = {10.3390/foods10020375}, journal-iso = {FOODS}, journal = {FOODS}, volume = {10}, unique-id = {32324158}, issn = {2304-8158}, abstract = {Maize is an important worldwide commodity susceptible to fungal contamination in the field, at harvest, and during storage. This work aimed to determine the occurrence of Fusarium spp. in maize grains produced in the Tagus Valley region of Portugal and the levels of related mycotoxins in the 2018 harvest and during their storage for six months in barrels, mimicking silos conditions. Continuous monitoring of temperature, CO2, and relative humidity levels were done, as well as the concentration of mycotoxins were evaluated and correlated with the presence of Fusarium spp. F. verticillioides was identified as the predominant Fusarium species. Zearalenone, deoxynivalenol and toxin T2 were not found at harvest and after storage. Maize grains showed some variability in the levels of fumonisins (Fum B1 and Fum B2). At the harvest, fumonisin B1 ranged from 1297 to 2037 mu g/kg, and fumonisin B2 ranged from 411 to 618 mu g/kg. Fumonisins showed a tendency to increase (20 to 40%) during six months of storage. Although a correlation between the levels of fumonisins and the monitoring parameters was not established, CO2 levels may be used to predict fungal activity during storage. The composition of the fungal population during storage may predict the incidence of mycotoxins.}, keywords = {MONITORING; CO2; Fumonisins; Climatic conditions; Zea mays L; Fusarium spp}, year = {2021}, eissn = {2304-8158}, orcid-numbers = {Carbas, Bruna/0000-0002-5941-8749; Simoes, Daniela/0000-0002-6149-6631; Freitas, Andreia/0000-0003-3292-5473; Ferreira, Bruno/0000-0003-2362-5399} } @article{MTMT:32303820, title = {Research Progress on Fumonisin B1 Contamination and Toxicity: A Review}, url = {https://m2.mtmt.hu/api/publication/32303820}, author = {Chen, Jia and Wen, Jun and Tang, Yating and Shi, Jichao and Mu, Guodong and Yan, Rong and Cai, Jing and Long, Miao}, doi = {10.3390/molecules26175238}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {26}, unique-id = {32303820}, issn = {1431-5157}, abstract = {Fumonisin B1 (FB1), belonging to the member of fumonisins, is one of the most toxic mycotoxins produced mainly by Fusarium proliferatum and Fusarium verticillioide. FB1 has caused extensive contamination worldwide, mainly in corn, rice, wheat, and their products, while it also poses a health risk and is toxic to animals and human. It has been shown to cause oxidative stress, endoplasmic reticulum stress, cellular autophagy, and apoptosis. This review focuses on the current stage of FB1 contamination, its toxic effects of acute toxicity, immunotoxicity, organ toxicity, and reproductive toxicity on animals and humans. The potential toxic mechanisms of FB1 are discussed. One of the main aims of the work is to provide a reliable reference strategy for understanding the occurrence and toxicity of FB1.}, keywords = {MECHANISM; review; TOXICITY; CONTAMINATION; Fumonisin B1}, year = {2021}, eissn = {1420-3049} } @article{MTMT:31860173, title = {Effect of fumonisin B 1 on oxidative stress and gene expression alteration of nutrient transporters in porcine intestinal cells}, url = {https://m2.mtmt.hu/api/publication/31860173}, author = {Chen, Zhigang and Zhou, Lihua and Yuan, Qiaoling and Chen, Huiyu and Lei, Hongyu and Su, Jianming}, doi = {10.1002/jbt.22706}, journal-iso = {J BIOCHEM MOL TOXIC}, journal = {JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY}, volume = {35}, unique-id = {31860173}, issn = {1095-6670}, year = {2021}, eissn = {1099-0461}, orcid-numbers = {Chen, Zhigang/0000-0001-6978-2942} } @article{MTMT:32338377, title = {Chronic aflatoxin M1 exposure of Hungarian consumers}, url = {https://m2.mtmt.hu/api/publication/32338377}, author = {Kerekes, Kata and Csorba, Szilveszter and Ambrus, Árpád}, doi = {10.52091/EVIK-2021/2-2-ENG}, journal-iso = {ÉLELMISZERVIZSGÁLATI KÖZLEMÉNYEK}, journal = {ÉLELMISZERVIZSGÁLATI KÖZLEMÉNYEK}, volume = {67}, unique-id = {32338377}, issn = {0422-9576}, abstract = {The mycotoxin contamination of foods also appears in the food chain. Aflatoxin is metabolized in animals and its aflatoxin M1 (AFM1) metabolite, which is similarly, but ten times less genotoxic and carcinogenic than aflatoxin B1 (AFB1), is also present in milk, liver and eggs. Of these, the most significant food safety risk is posed by the contamination of milk with AFM1. In our article, the deterministic exposure estimation of Hungarian consumers is presented, based on the AFM1 contamination of milk and dairy products. The results indicate that the exposure of children under three years of age clearly poses a health risk, while the exposure of the 3 to 6 year old age group is borderline. The exposure of older age groups in ng/kg body weight does not pose an immediate health risk due to the increasing body weight. However, it needs to be emphasized that the presence of carcinogenic compounds should be kept to a minimum in all age groups. To this end, we propose an amendment to the regulation regarding the factory inspection of milk.}, keywords = {deterministic exposure estimation; chronic aflatoxin M1 exposure; consumer groups at risk; Carcinogenic effect; Risk of liver cancer 1. SUMMARY}, year = {2021}, eissn = {2676-8704}, pages = {3402-3420}, orcid-numbers = {Csorba, Szilveszter/0000-0002-2238-4469} } @article{MTMT:32580269, title = {Levels of filamentous fungi and selected mycotoxins in leafy and fruit vegetables and analysis of their potential health risk for consumers}, url = {https://m2.mtmt.hu/api/publication/32580269}, author = {Kłapeć, Teresa and Wójcik-Fatla, Angelina and Farian, Ewelina and Kowalczyk, Katarzyna and Cholewa, Grażyna and Cholewa, Alicja and Dutkiewicz, Jacek}, doi = {10.26444/aaem/143031}, journal-iso = {ANN AGR ENV MED}, journal = {ANNALS OF AGRICULTURAL AND ENVIRONMENTAL MEDICINE}, volume = {28}, unique-id = {32580269}, issn = {1232-1966}, abstract = {Introduction and Objective. The aim of the study was to determine the presence, concentration and generic composition of filamentous fungi. Considering the significant role of mycotoxins in the pathogenicity of fungal contaminants of vegetables, the scope of the study was extended by determination of aflatoxins and deoxynivalenol. Materials and method. In the years 2019–2020, samples of vegetables (lettuce, spinach, tomato, red pepper) collected on conventional farms located in eastern Poland were subjected to mycological examination. The concentration and species composition of filamentous fungi were determined by the method of plate dilutions on malt agar. The isolated strains were identified with the use of macroscopic and microscopic methods. Samples were also analyzed for the presence of aflatoxin B1 (AFB1), total aflatoxin (AFT) and deoxynivalenol (DON) using the immunoenzymatic ELISA method. Results. The median concentrations of filamentous fungi ranged from 2.778–3.204 log10 CFU g-1. Overall, 40 fungal species were identified in the examined vegetables, of which 38 are classified as potentially pathogenic for humans. The mean prevalence values for AFB1 and AFT were moderate or high (16.0–60.0% and 57.8–75.6%, respectively) and very low for DON (0–2.2%). The median concentrations of filamentous fungi, AFB1 and AFT were distinctly greater in leafy vegetables than on non-leafy tomato and pepper fruits, and the differences were highly significant (P<0.001). Conclusions. The levels of filamentous fungi and mycotoxins in Polish vegetables could be classified as moderate or low. The abundant presence of species with various pathogenic abilities may pose a risk for some categories of people consuming raw vegetables, mostly for immuno-compromised persons or atopics susceptible to food allergy caused by ingested moulds. © 2021, Institute of Agricultural Medicine. All rights reserved.}, keywords = {VEGETABLES; Deoxynivalenol; health hazard; Aflatoxins; food safety; Filamentous fungi}, year = {2021}, eissn = {1898-2263}, pages = {585-594}, orcid-numbers = {Kłapeć, Teresa/0000-0001-7735-3873; Wójcik-Fatla, Angelina/0000-0001-5260-4867; Farian, Ewelina/0000-0003-0135-2959; Kowalczyk, Katarzyna/0000-0002-4061-9890; Cholewa, Grażyna/0000-0001-6548-522X; Cholewa, Alicja/0000-0002-2210-923X; Dutkiewicz, Jacek/0000-0003-1965-8702} } @article{MTMT:32324156, title = {Effect of Popcorn (Zea mays var. everta) Popping Mode (Microwave, Hot Oil, and Hot Air) on Fumonisins and Deoxynivalenol Contamination Levels}, url = {https://m2.mtmt.hu/api/publication/32324156}, author = {Schambri, Pierre and Brunet, Sophie and Bailly, Jean-Denis and Kleiber, Didier and Levasseur-Garcia, Cecile}, doi = {10.3390/toxins13070486}, journal-iso = {TOXINS}, journal = {TOXINS}, volume = {13}, unique-id = {32324156}, issn = {2072-6651}, abstract = {Mycotoxins are secondary metabolites that are produced by molds during their development. According to fungal physiological particularities, mycotoxins can contaminate crops before harvest or during storage. Among toxins that represent a real public health issue, those produced by Fusarium genus in cereals before harvest are of great importance since they are the most frequent in European productions. Among them, deoxynivalenol (DON) and fumonisins (FUM) frequently contaminate maize. In recent years, numerous studies have investigated whether food processing techniques can be exploited to reduce the levels of these two mycotoxins, which would allow the identification and quantification of parameters affecting mycotoxin stability. The particularity of the popcorn process is that it associates heat treatment with a particular physical phenomenon (i.e., expansion). Three methods exist to implement the popcorn transformation process: hot air, hot oil, and microwaves, all of which are tested in this study. The results show that all popping modes significantly reduce FUM contents in both Mushroom and Butterfly types of popcorn. The mean initial contamination of 1351 mu g/kg was reduced by 91% on average after popping. For DON, the reduction was less important despite a lower initial contamination than for FUM (560 mu g/kg). Only the hot oil popping for the Mushroom type significantly reduced the contamination up to 78% compared to unpopped controls. Hot oil popping appears to provide the most important reduction for the two considered mycotoxins for both types of popcorn (-98% and -58% average reduction for FUM and DON, respectively).}, keywords = {Deoxynivalenol; Fumonisins; popcorn; popping; mycotoxins reduction}, year = {2021}, eissn = {2072-6651} } @article{MTMT:32917853, title = {Determination of Fusarium mycotoxin exposure in humans based on urine samples, using One Health approach}, url = {https://m2.mtmt.hu/api/publication/32917853}, author = {Schieszl, Tamás and Szabó-Fodor, Judit and Kovács, Melinda}, doi = {10.31914/aak.2601}, journal-iso = {ACTA AGRARIA KAPOSV}, journal = {ACTA AGRARIA KAPOSVÁRIENSIS}, volume = {25}, unique-id = {32917853}, issn = {1418-1789}, keywords = {FUSARIUM MYCOTOXINS; HUMAN EXPOSURE; Urinary biomarker}, year = {2021}, pages = {53-68}, orcid-numbers = {Szabó-Fodor, Judit/0000-0002-5492-3447; Kovács, Melinda/0000-0001-5988-3934} } @article{MTMT:31372925, title = {Food safety assessment of the mycotoxin and pesticide residue contamination of our foods, part 2. Mycotoxins}, url = {https://m2.mtmt.hu/api/publication/31372925}, author = {Ambrus, Árpád and Szenczi-Cseh, Júlia and Griff, Tamás and Kerekes, Kata and Miklós, Gabriella and Vásárhelyi, Adrienn and Szigeti, Tamás János}, journal-iso = {ÉLELMISZERVIZSGÁLATI KÖZLEMÉNYEK}, journal = {ÉLELMISZERVIZSGÁLATI KÖZLEMÉNYEK}, volume = {66}, unique-id = {31372925}, issn = {0422-9576}, abstract = {The occurrence, legal regulation, quality requirements for sampling and analysis of mycotoxins occurring in food and feed in Hungary are presented. Furthermore, the current practice is evaluated. To complement the test results of NÉBIH, the WESSLING Hungary Ltd. and the University of Kaposvár provided detailed analytical results for the assessment of consumers’ exposure. Besides, the BIOMIN Ltd. and the SGS Hungária Ltd. shared their annual summary data, the Gabona Control Ltd. made available partial test results for preparing this paper. Based on the available data and information, the exposure of Hungarian consumers to Aflatoxin M1 and DON is estimated, and recom-mendations are made for facilitating the actions aiming to reduce the contamination of our food. Taking into account the extensive national test results and international information, we concluded that: • the exposure of consumers to Aflatoxin M1 and DON may exceed the toxicological reference values from time to time, posing a risk to consumers’ the health; • there is a need for coordinated comprehensive actions by all interested parties for the reduction of Aspergillus and Fusarium fungi infections in cereals and the resulted toxin exposure. © 2020, Wessling International Research and Educational Centre Nonprofit Beneficial Ltd.. All rights reserved.}, keywords = {quality control; MYCOTOXINS; sampling; mikotoxinok; mintavétel; Codex Alimentarius; Consumer’s exposure; fogyasztói expozíció; minőség-ellenőrzés}, year = {2020}, eissn = {2676-8704}, pages = {2922-2949} } @article{MTMT:31387476, title = {Fusarium head blight, mycotoxins and strategies for their reduction}, url = {https://m2.mtmt.hu/api/publication/31387476}, author = {Mielniczuk, E. and Skwaryło-Bednarz, B.}, doi = {10.3390/agronomy10040509}, journal-iso = {AGRONOMY-BASEL}, journal = {AGRONOMY (BASEL)}, volume = {10}, unique-id = {31387476}, keywords = {CEREALS; MYCOTOXINS; Plant protection; scab; Fusarium spp; Post-harvest strategies; Pre-harvest strategies}, year = {2020}, eissn = {2073-4395} } @article{MTMT:31551300, title = {A Long Road to Safer Food}, url = {https://m2.mtmt.hu/api/publication/31551300}, author = {Rossi, Filippo}, doi = {10.3390/toxins12070453}, journal-iso = {TOXINS}, journal = {TOXINS}, volume = {12}, unique-id = {31551300}, issn = {2072-6651}, year = {2020}, eissn = {2072-6651}, orcid-numbers = {Rossi, Filippo/0000-0002-0313-4210} }