TY - JOUR AU - Lee, Mon-Chien AU - Hsu, Yi-Ju AU - Shen, Sih-Yu AU - Ho, Chin-Shan AU - Huang, Chi-Chang TI - A functional evaluation of anti-fatigue and exercise performance improvement following vitamin B complex supplementation in healthy humans, a randomized double-blind trial JF - INTERNATIONAL JOURNAL OF MEDICAL SCIENCES J2 - INT J MED SCI VL - 20 PY - 2023 IS - 10 SP - 1272 EP - 1281 PG - 10 SN - 1449-1907 DO - 10.7150/ijms.86738 UR - https://m2.mtmt.hu/api/publication/34331085 ID - 34331085 N1 - Export Date: 28 November 2023 AB - B vitamins play a crucial role in maintaining fundamental cellular functions and various essential metabolic pathways in the body. Although they do not directly provide energy, each B vitamin acts as a cofactor in energy metabolism processes. Based on the evidence presented above, we hypothesized that a 28-day supplementation of vitamin B would enhance physical performance and reduce physical fatigue. The objective of this study was to evaluate the anti-fatigue effect of vitamin B supplementation, specifically vitamin B1, B2, B6, and B12, and its potential to improve exercise performance. We employed a randomized double-blind crossover design with a 28-day supplementation period. Sixteen male and sixteen female subjects, aged 20-30 years, were divided into two groups: the placebo group (n=16, equal gender distribution) and the Ex PLUS (R) group (n=16, equal gender distribution). The participants received either placebo or Ex PLUS (R) (one tablet per day) for 28 consecutive days. Following the intervention, there was a 14-day wash-out period during which the subjects did not receive any further interventions. After supplementation with Ex PLUS., we found a significant increase in the running time by 1.26-fold ( p < 0.05) to exhaustion compared to that before supplementation and that in the placebo group. In addition, the Ex PLUS. supplementation group presented significantly reduced blood lactate and blood ammonia concentrations during exercise and at rest after exercise compared with placebo (p < 0.05). In conclusion, 28 consecutive days of vitamin B complex (Ex PLUS.) supplementation significantly improved exercise endurance performance and reduced exercise fatigue biochemical metabolites in not athletes. In addition, it does not cause adverse effects in humans when taken at appropriate doses. LA - English DB - MTMT ER - TY - JOUR AU - Rai, A. AU - Bhati, P. AU - Anand, P. TI - Exercise induced muscle damage and repeated bout effect: an update for last 10 years and future perspectives JF - COMPARATIVE EXERCISE PHYSIOLOGY J2 - COMPARATIVE EXERCISE PHYSIOLOGY VL - 19 PY - 2023 IS - 1 SP - 49 EP - 61 PG - 13 SN - 1755-2540 DO - 10.3920/CEP220025 UR - https://m2.mtmt.hu/api/publication/33803162 ID - 33803162 N1 - Export Date: 8 May 2023 LA - English DB - MTMT ER - TY - CHAP AU - Reaburn, P.R. AU - Fernandes, J.F.T. TI - Exercise stress and recovery in active ageing individuals and masters athletes T2 - The Importance of Recovery for Physical and Mental Health: Negotiating the Effects of Underrecovery PB - Taylor and Francis SN - 9781032168586 T3 - The Importance of Recovery for Physical and Mental Health: Negotiating the Effects of Underrecovery PY - 2023 SP - 242 EP - 265 PG - 24 DO - 10.4324/9781003250647-14 UR - https://m2.mtmt.hu/api/publication/33803172 ID - 33803172 N1 - Export Date: 8 May 2023 LA - English DB - MTMT ER - TY - JOUR AU - de, Almeida Paz I. AU - Frigotto, M.F. AU - Cardoso, C.A. AU - Rabello, R. AU - Rodrigues, R. TI - Hip abduction machine is better than free weights to target the gluteus medius while minimizing tensor fascia latae activation JF - JOURNAL OF BODYWORK AND MOVEMENT THERAPIES J2 - J BODYWORK MOVEMENT THERAPIES VL - 30 PY - 2022 SP - 160 EP - 167 PG - 8 SN - 1360-8592 DO - 10.1016/j.jbmt.2022.01.001 UR - https://m2.mtmt.hu/api/publication/32814674 ID - 32814674 N1 - Exercise Research Laboratory, Federal University of Rio Grande do Sul, RS, Porto Alegre, Brazil Exercise Physiology and Physical Assessment Laboratory, Serra Gaúcha University Center, RS, Caxias do Sul, Brazil Department of Biomedical Sciences for Health, University of Milan, MI, Milan, Italy Physical Therapy Department, Sogipa College, RS, Porto Alegre, Brazil Export Date: 10 May 2022 CODEN: JBOTF Correspondence Address: de Almeida Paz, I.; Exercise Research Laboratory, Felizardo Street, 750, Postal Code 90690-200, RS, Brazil; email: isabel.paz@ufrgs.br LA - English DB - MTMT ER - TY - JOUR AU - Rader, Erik P. AU - Baker, Brent A. TI - Elevated muscle mass accompanied by transcriptional and nuclear alterations several months following cessation of resistance-type training in rats JF - PHYSIOLOGICAL REPORTS J2 - PHYSIOL REPORTS VL - 10 PY - 2022 IS - 20 PG - 12 SN - 2051-817X DO - 10.14814/phy2.15476 UR - https://m2.mtmt.hu/api/publication/33218789 ID - 33218789 AB - Rodent studies investigating long-term effects following termination of hypertrophy-inducing loading have predominantly involved exposures such as synergist ablation and weighted wheel running or ladder climbing. This research yielded a spectrum of results regarding the extent of detraining in terms of muscle mass and myonuclei number. The studies were also limited in their lack of sensitive performance measures and indirect relatedness to resistance training. Our research group developed and validated a relevant rat model of resistance-type training that induces increased muscle mass and performance. The aim of the present study was to determine to what extent these features persist 3 months following the termination of this training. While performance returned to baseline, muscle mass remained elevated by 17% and a shift in distribution to larger muscle fibers persisted. A 16% greater total RNA and heightened mRNA levels of ribosomal protein S6 kinases implicated preserved transcriptional output and ribosomal content. Remodeling of muscle fiber nuclei was consistent with these findings - increased nuclear number and a distribution shift to a more circular nuclear shape. These findings indicate that muscle mass detrains at a slower rate than performance and implicates multiple forms of myonuclear remodeling in muscle memory. LA - English DB - MTMT ER - TY - JOUR AU - Ruas, C.V. AU - Latella, C. AU - Taylor, J.L. AU - Haff, G.G. AU - Nosaka, K. TI - Comparison between Eccentric-Only and Coupled Concentric-Eccentric Contractions for Neuromuscular Fatigue and Muscle Damage JF - MEDICINE AND SCIENCE IN SPORTS AND EXERCISE J2 - MED SCI SPORT EXER VL - 54 PY - 2022 IS - 10 SP - 1635 EP - 1646 PG - 12 SN - 0195-9131 DO - 10.1249/MSS.0000000000002959 UR - https://m2.mtmt.hu/api/publication/33200864 ID - 33200864 N1 - Export Date: 8 May 2023 CODEN: MSCSB LA - English DB - MTMT ER - TY - JOUR AU - Elia, Antonis AU - Woods, David R. AU - Barlow, Matthew J. AU - Lees, Matthew J. AU - O'Hara, John P. TI - Cerebral, cardiac and skeletal muscle stress associated with a series of static and dynamic apnoeas JF - SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS J2 - SCAND J MED SCI SPOR VL - 32 PY - 2021 IS - 1 SP - 233 EP - 241 PG - 9 SN - 0905-7188 DO - 10.1111/sms.14067 UR - https://m2.mtmt.hu/api/publication/32721157 ID - 32721157 N1 - Funding Agency and Grant Number: Leeds Beckett University Funding text: This study was funded by Leeds Beckett University AB - Purpose This study sought to explore, for the first time, the effects of repeated maximal static and dynamic apnoeic attempts on the physiological milieu by assessing cerebral, cardiac and striatal muscle stress-related biomarkers in a group of elite breath-hold divers (EBHD). Methods Sixteen healthy males were recruited (EBHD = 8; controls = 8). On two separate occasions, EBHD performed two sets of five repeated maximal static apnoeas (STA) or five repeated maximal dynamic apnoeas (DYN). Controls performed a static eupnoeic protocol to negate any effects of water immersion and diurnal variation on haematology (CTL). Venous blood samples were drawn at 30, 90, and 180 min after each protocol to determine S100 beta, neuron-specific enolase (NSE), myoglobin, and high sensitivity cardiac troponin T (hscTNT) concentrations. Results S100 beta and myoglobin concentrations were elevated following both apnoeic interventions (p p <= 0.028, respectively) but not after CTL (p >= 0.348). S100 beta increased from baseline (0.024 +/- 0.005 mu g/L) at 30 (STA, +149%, p < 0.001; DYN, +166%, p < 0.001) and 90 min (STA, +129%, p < 0.001; DYN, +132%, p = 0.008) following the last apnoeic repetition. Myoglobin was higher than baseline (22.3 +/- 2.7 ng/ml) at 30 (+42%, p = 0.04), 90 (+64%, p < 0.001) and 180 min (+49%, p = 0.013) post-STA and at 90 min (+63%, p = 0.016) post-DYN. Post-apnoeic S100 beta and myoglobin concentrations were higher than CTL (STA, p < 0.001; DYN, p <= 0.004). NSE and hscTNT did not change from basal concentrations after the apnoeic (p >= 0.146) nor following the eupnoeic (p >= 0.553) intervention. Conclusions This study suggests that a series of repeated maximal static and dynamic apnoeas transiently disrupt the blood-brain barrier and instigate muscle injury but do not induce neuronal-parenchymal damage or myocardial damage. LA - English DB - MTMT ER - TY - JOUR AU - Fernandes, John F. T. AU - Lamb, Kevin L. AU - Norris, Jonathan P. AU - Moran, Jason AU - Drury, Benjamin AU - Borges, Nattai R. AU - Twist, Craig TI - Aging and Recovery After Resistance-Exercise-Induced Muscle Damage: Current Evidence and Implications for Future Research JF - JOURNAL OF AGING AND PHYSICAL ACTIVITY J2 - J AGING PHYS ACTIV VL - 29 PY - 2021 IS - 3 SP - 544 EP - 551 PG - 8 SN - 1063-8652 DO - 10.1123/japa.2020-0201 UR - https://m2.mtmt.hu/api/publication/32316663 ID - 32316663 N1 - Higher Education Sport, Hartpury University, Hartpury, United Kingdom Department of Sport and Exercise Sciences, University of Chester, Chester, United Kingdom Derbyshire County Cricket Club, Derby, United Kingdom School of Sport Rehabilitation and Exercise Sciences, University of Essex, Colchester, United Kingdom School of Environmental and Life Sciences, The University of Newcastle, Newcastle, Australia Cited By :1 Export Date: 4 March 2022 CODEN: JAPAF Correspondence Address: Fernandes, J.F.T.; Higher Education Sport, United Kingdom; email: jfmtfernandes@hotmail.co.uk AB - Aging is anecdotally associated with a prolonged recovery from resistance training, though current literature remains equivocal. This brief review considers the effects of resistance training on indirect markers of muscle damage and recovery (i.e., muscle soreness, blood markers, and muscle strength) in older males. With no date restrictions, four databases were searched for articles relating to aging, muscle damage, and recovery. Data from 11 studies were extracted for review. Of these, four reported worse symptoms in older compared with younger populations, while two have observed the opposite, and the remaining studies (n = 6) proposed no differences between age groups. It appears that resistance training can be practiced in older populations without concern for impaired recovery. To improve current knowledge, researchers are urged to utilize more ecologically valid muscledamaging bouts and investigate the mechanisms which underpin the recovery of muscle soreness and strength after exercise in older populations. LA - English DB - MTMT ER - TY - JOUR AU - Huang, Chi-Chang AU - Lee, Mon-Chien AU - Ho, Chin-Shan AU - Hsu, Yi-Ju AU - Ho, Chien-Chang AU - Kan, Nai-Wen TI - Protective and Recovery Effects of Resveratrol Supplementation on Exercise Performance and Muscle Damage following Acute Plyometric Exercise JF - NUTRIENTS J2 - NUTRIENTS VL - 13 PY - 2021 IS - 9 PG - 14 SN - 2072-6643 DO - 10.3390/nu13093217 UR - https://m2.mtmt.hu/api/publication/32316662 ID - 32316662 N1 - Funding Agency and Grant Number: Ministry of Science and Technology of TaiwanMinistry of Science and Technology, Taiwan [MOST 108-2410-H-038-016-MY2] Funding text: This study was supported by the Ministry of Science and Technology of Taiwan. The grant number is MOST 108-2410-H-038-016-MY2. AB - Plyometric exercise (PE) is an effective training method to increase muscle mass and strength. However, excessive or inappropriate conditions might cause exercise-induced muscle damage (EIMD). Resveratrol (RES) is a natural polyphenol plant antitoxin, which improves exercise performance, and exhibits anti-oxidation, anti-inflammatory, and anti-cancer effects. Therefore, this study investigated the effect of RES supplementation on the recovery of muscle damage, inflammation, soreness, muscle power, and anaerobic performance following plyometric-exercise-induced muscle damage (PEIMD). The present study was a double-blind, placebo-controlled research trial. Thirty-six young, untrained males were enrolled into the placebo (n = 12), RES-500 (500 mg RES/day, n = 12), or RES-1000 (1000 mg RES/day, n = 12) group by a jumping height-counterbalanced grouping design. At baseline, to pre-PEIMD, supplements were pre-loaded 7 days before they conducted PEIMD, and the exercise performance, delayed-onset muscle soreness (DOMS) and muscle damage biomarkers were measured over the experimental period at baseline, pre-PEIMD, and post-PEIMD at 2, 24, 48, and 72 h. As a result, we found that, at 72 h post-EIMD, the force peak (FP) and rate of force development (RFD) of the counter movement jump (CMJ) in RES groups showed no significant difference compared to that at baseline but was significantly greater than the placebo group. In the Wingate anaerobic test (WAnT), supplementation in the RES group had a better recovery effect on the relative peak power (RPP), relative mean power (RMP) and fatigue index (FI) (p < 0.05), especially in the high-dose group. For the detection of muscle pain after PEIMD, the RES supplement group was significantly better than the placebo group (p < 0.05). In addition, for muscle damage indexes, such as creatine kinase (CK) and lactate dehydrogenase (LDH), after PEIMD, supplementation with RES could significantly reduce and accelerate recovery (p < 0.05). In addition, the blood biochemical indicators of blood count, liver function, and kidney function showed that RES will not cause adverse risks to the human body. Our results suggest that replenishing RES in advance could effectively reduce muscle pain, increase exercise performance, and decrease muscle damage indicators caused by PEIMD, and the recovery was faster. Therefore, plyometric exercises combined with suitable RES supplementation could be an effective candidate for controlling muscle damage, improving physical adaption, and recovering anaerobic capacity. LA - English DB - MTMT ER - TY - JOUR AU - Kyriakidou, Y. AU - Cooper, I. AU - Kraev, I. AU - Lange, S. AU - Elliott, B.T. TI - Preliminary Investigations Into the Effect of Exercise-Induced Muscle Damage on Systemic Extracellular Vesicle Release in Trained Younger and Older Men JF - FRONTIERS IN PHYSIOLOGY J2 - FRONT PHYSIOL VL - 12 PY - 2021 SN - 1664-042X DO - 10.3389/fphys.2021.723931 UR - https://m2.mtmt.hu/api/publication/32478847 ID - 32478847 N1 - Translational Physiology Research Group, School of Life Sciences, University of Westminster, London, United Kingdom Electron Microscopy Suite, Faculty of Science, Technology, Engineering and Mathematics, Open University, Milton Keynes, United Kingdom Tissue Architecture and Regeneration Research Group, School of Life Sciences, University of Westminster, London, United Kingdom Export Date: 5 November 2021 Correspondence Address: Elliott, B.T.; Translational Physiology Research Group, United Kingdom; email: b.elliott@westminster.ac.uk AB - Background: Exercise-induced muscle damage (EIMD) results in transient muscle inflammation, strength loss, and muscle soreness and may cause subsequent exercise avoidance. Research has recently proven that skeletal muscle can also release extracellular vesicles (EVs) into the circulation following a bout of exercise. However, EV’s potential role, including as a biomarker, in the response to eccentric resistance exercise stimulus remains unclear. Methods: Twelve (younger, n=7, 27.0±1.5years and older, n=5, 63.0±1.0years) healthy, physically active males, undertaking moderate, regular physical activity (3–5 times per week) performed a unilateral high intensity eccentric exercise protocol. Venous plasma was collected for assessment of EVs and creatine kinase (CK) prior to EIMD, immediately after EIMD, and 1–72h post-EIMD, and maximal voluntary isometric contraction (MVIC) and delayed onset muscle soreness (DOMS) were assessed at all time points, except 1 and 2h post-EIMD. Results: A significant effect of both time (p=0.005) and group (p<0.001) was noted for MVIC, with younger participants’ MVIC being higher throughout. Whilst a significant increase was observed in DOMS in the younger group (p=0.014) and in the older group (p=0.034) following EIMD, no significant differences were observed between groups. CK was not different between age groups but was altered following the EIMD (main effect of time p=0.026), with increased CK seen immediately post-, at 1 and 2h post-EIMD. EV count tended to be lower in older participants at rest, relative to younger participants (p=0.056), whilst EV modal size did not differ between younger and older participants pre-EIMD. EIMD did not substantially alter EV modal size or EV count in younger or older participants; however, the alteration in EV concentration (ΔCount) and EV modal size (ΔMode) between post-EIMD and pre-EIMD negatively associated with CK activity. No significant associations were noted between MVIC or DOMS and either ΔCount or ΔMode of EVs at any time point. Conclusion: These findings suggest that profile of EV release, immediately following exercise, may predict later CK release and play a role in the EIMD response. Exercise-induced EV release profiles may therefore serve as an indicator for subsequent muscle damage. © Copyright © 2021 Kyriakidou, Cooper, Kraev, Lange and Elliott. LA - English DB - MTMT ER - TY - JOUR AU - Lee, Mon-Chien AU - Hsu, Yi-Ju AU - Ho, Chin-Shan AU - Chang, Chun-Hao AU - Liu, Ching-Wen AU - Huang, Chi-Chang AU - Chiang, Wen-Dee TI - Evaluation of the Efficacy of Supplementation with Planox® Lemon Verbena Extract in Improving Oxidative Stress and Muscle Damage: A Double-Blind Controlled Trial JF - INTERNATIONAL JOURNAL OF MEDICAL SCIENCES J2 - INT J MED SCI VL - 18 PY - 2021 IS - 12 SP - 2641 EP - 2652 PG - 12 SN - 1449-1907 DO - 10.7150/ijms.60726 UR - https://m2.mtmt.hu/api/publication/32080084 ID - 32080084 N1 - Graduate Institute of Sports Science, National Taiwan Sport University, Taoyuan City, 33301, Taiwan Department of Food Science, College of Agriculture, Tunghai University, Taichung City, 40704, Taiwan Cited By :2 Export Date: 4 March 2022 Correspondence Address: Huang, C.-C.; Graduate Institute of Sports Science, Taiwan; email: john5523@ntsu.edu.tw Correspondence Address: Chiang, W.-D.; Department of Food Science, Taiwan; email: wdc@thu.edu.tw LA - English DB - MTMT ER - TY - JOUR AU - Lee, Minjung AU - Goral, Kamil AU - Flis, DamianJ AU - Skrobot, Wojciech AU - Cieminski, Karol AU - Olek, RobertA AU - Akimoto, Takayuki AU - Ziolkowski, Wieslaw TI - Changes in Urinary Titin Fragment in Response to Different Types of Dynamic Eccentric Exercises JF - INTERNATIONAL JOURNAL OF SPORTS MEDICINE J2 - INT J SPORTS MED VL - 42 PY - 2020 IS - 05 SP - 432 EP - 440 PG - 9 SN - 0172-4622 DO - 10.1055/a-1273-8082 UR - https://m2.mtmt.hu/api/publication/31689857 ID - 31689857 N1 - Funding Agency and Grant Number: Waseda University; High Performance Sport Center Total Conditioning Research Project from the Japan Sport Council; Japan Society for the Promotion of Science (JSPS)Ministry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of Science Funding text: This study was supported, in part, by Grants-in Aid by Waseda University and the High Performance Sport Center Total Conditioning Research Project from the Japan Sport Council. ML was supported by the Japan Society for the Promotion of Science (JSPS) Postdoctoral Fellowships for research in Japan. AB - The urinary level of the titin fragment has been considered a non-invasive and sensitive biomarker for muscle damage in clinical cases. However, there is little evidence regarding changes in the urinary titin fragment in response to exercise-induced muscle damage. In this study, we aimed to investigate whether the urinary titin fragment reflects the magnitude of muscle damage induced by two lower-limb eccentric exercises. In this study, healthy young male subjects performed drop jump (n=9) and eccentric ergometer exercise (n=9). Blood and urine samples were collected at various time points before and after the exercises. Although perceived muscle soreness assessed by sit-to-stand tasks was increased at 24h and 48h after both drop jump and the eccentric ergometer exercise groups, the pressure pain threshold was not changed. Changes of the urinary titin fragment, plasma myomesin 3 fragments, creatine kinase (CK), and myoglobin (Mb) after the eccentric exercises were increased but not statistically significant. Meanwhile, we found that the changes in the urinary titin fragment levels in response to both drop jump and the eccentric ergometer exercise were correlated with those of plasma CK and Mb levels. These results provide evidence that the urinary titin fragment level is a non-invasive biomarker reflecting the magnitude of eccentric exercise-induced muscle damage. LA - English DB - MTMT ER - TY - JOUR AU - Mielgo-Ayuso, Juan AU - Calleja-González, Julio AU - Refoyo, Ignacio AU - León-Guereño, Patxi AU - Cordova, Alfredo AU - Del Coso, Juan TI - Exercise-Induced Muscle Damage and Cardiac Stress During a Marathon Could be Associated with Dietary Intake During the Week Before the Race JF - NUTRIENTS J2 - NUTRIENTS VL - 12 PY - 2020 IS - 2 SN - 2072-6643 DO - 10.3390/nu12020316 UR - https://m2.mtmt.hu/api/publication/31908339 ID - 31908339 N1 - Department of Biochemistry Molecular Biology and Physiology, Faculty of Health Sciences, Campus de Soria, University of Valladolid, Soria, 42004, Spain Laboratory of Human Performance, Department of Physical Education and Sport, Faculty of Education, Sport Section, University of the Basque Country, Vitoria, 01007, Spain Department of Sports, Faculty of Physical Activity and Sports Sciences (INEF), Universidad Politécnica de Madrid, Madrid, 28040, Spain Faculty of Psychology and Education, University of Deusto, Campus of Donostia-San Sebastián, San Sebastián, Guipúzcoa 20012, Spain Centre for Sport Studies, Rey Juan Carlos University, Fuenlabrada, 28943, Spain Cited By :13 Export Date: 4 March 2022 Correspondence Address: Mielgo-Ayuso, J.; Department of Biochemistry Molecular Biology and Physiology, Spain; email: juanfrancisco.mielgo@uva.es LA - English DB - MTMT ER - TY - JOUR AU - Yoshimoto, Shunsuke AU - Ikemoto, Naoki AU - Ishizuka, Hiroki AU - Ikeda, Sei AU - Kuroda, Yoshihiro AU - Oshiro, Osamu TI - Efficient and Robust Detection of Local Impedance Changes Using Selected Electrical Excitation Conditions JF - IEEE ACCESS J2 - IEEE ACCESS VL - 8 PY - 2020 SP - 205778 EP - 205787 PG - 10 SN - 2169-3536 DO - 10.1109/ACCESS.2020.3037167 UR - https://m2.mtmt.hu/api/publication/31908342 ID - 31908342 N1 - Export Date: 12 October 2021 LA - English DB - MTMT ER -