@article{MTMT:34331085, title = {A functional evaluation of anti-fatigue and exercise performance improvement following vitamin B complex supplementation in healthy humans, a randomized double-blind trial}, url = {https://m2.mtmt.hu/api/publication/34331085}, author = {Lee, Mon-Chien and Hsu, Yi-Ju and Shen, Sih-Yu and Ho, Chin-Shan and Huang, Chi-Chang}, doi = {10.7150/ijms.86738}, journal-iso = {INT J MED SCI}, journal = {INTERNATIONAL JOURNAL OF MEDICAL SCIENCES}, volume = {20}, unique-id = {34331085}, issn = {1449-1907}, abstract = {B vitamins play a crucial role in maintaining fundamental cellular functions and various essential metabolic pathways in the body. Although they do not directly provide energy, each B vitamin acts as a cofactor in energy metabolism processes. Based on the evidence presented above, we hypothesized that a 28-day supplementation of vitamin B would enhance physical performance and reduce physical fatigue. The objective of this study was to evaluate the anti-fatigue effect of vitamin B supplementation, specifically vitamin B1, B2, B6, and B12, and its potential to improve exercise performance. We employed a randomized double-blind crossover design with a 28-day supplementation period. Sixteen male and sixteen female subjects, aged 20-30 years, were divided into two groups: the placebo group (n=16, equal gender distribution) and the Ex PLUS (R) group (n=16, equal gender distribution). The participants received either placebo or Ex PLUS (R) (one tablet per day) for 28 consecutive days. Following the intervention, there was a 14-day wash-out period during which the subjects did not receive any further interventions. After supplementation with Ex PLUS., we found a significant increase in the running time by 1.26-fold ( p < 0.05) to exhaustion compared to that before supplementation and that in the placebo group. In addition, the Ex PLUS. supplementation group presented significantly reduced blood lactate and blood ammonia concentrations during exercise and at rest after exercise compared with placebo (p < 0.05). In conclusion, 28 consecutive days of vitamin B complex (Ex PLUS.) supplementation significantly improved exercise endurance performance and reduced exercise fatigue biochemical metabolites in not athletes. In addition, it does not cause adverse effects in humans when taken at appropriate doses.}, keywords = {Health; ENDURANCE; Exercise performance; B vitamins; antifatigue}, year = {2023}, eissn = {1449-1907}, pages = {1272-1281} } @article{MTMT:33803162, title = {Exercise induced muscle damage and repeated bout effect: an update for last 10 years and future perspectives}, url = {https://m2.mtmt.hu/api/publication/33803162}, author = {Rai, A. and Bhati, P. and Anand, P.}, doi = {10.3920/CEP220025}, journal-iso = {COMPARATIVE EXERCISE PHYSIOLOGY}, journal = {COMPARATIVE EXERCISE PHYSIOLOGY}, volume = {19}, unique-id = {33803162}, issn = {1755-2540}, year = {2023}, pages = {49-61} } @{MTMT:33803172, title = {Exercise stress and recovery in active ageing individuals and masters athletes}, url = {https://m2.mtmt.hu/api/publication/33803172}, author = {Reaburn, P.R. and Fernandes, J.F.T.}, booktitle = {The Importance of Recovery for Physical and Mental Health: Negotiating the Effects of Underrecovery}, doi = {10.4324/9781003250647-14}, unique-id = {33803172}, year = {2023}, pages = {242-265} } @article{MTMT:32814674, title = {Hip abduction machine is better than free weights to target the gluteus medius while minimizing tensor fascia latae activation}, url = {https://m2.mtmt.hu/api/publication/32814674}, author = {de, Almeida Paz I. and Frigotto, M.F. and Cardoso, C.A. and Rabello, R. and Rodrigues, R.}, doi = {10.1016/j.jbmt.2022.01.001}, journal-iso = {J BODYWORK MOVEMENT THERAPIES}, journal = {JOURNAL OF BODYWORK AND MOVEMENT THERAPIES}, volume = {30}, unique-id = {32814674}, issn = {1360-8592}, year = {2022}, eissn = {1532-9283}, pages = {160-167} } @article{MTMT:33218789, title = {Elevated muscle mass accompanied by transcriptional and nuclear alterations several months following cessation of resistance-type training in rats}, url = {https://m2.mtmt.hu/api/publication/33218789}, author = {Rader, Erik P. and Baker, Brent A.}, doi = {10.14814/phy2.15476}, journal-iso = {PHYSIOL REPORTS}, journal = {PHYSIOLOGICAL REPORTS}, volume = {10}, unique-id = {33218789}, abstract = {Rodent studies investigating long-term effects following termination of hypertrophy-inducing loading have predominantly involved exposures such as synergist ablation and weighted wheel running or ladder climbing. This research yielded a spectrum of results regarding the extent of detraining in terms of muscle mass and myonuclei number. The studies were also limited in their lack of sensitive performance measures and indirect relatedness to resistance training. Our research group developed and validated a relevant rat model of resistance-type training that induces increased muscle mass and performance. The aim of the present study was to determine to what extent these features persist 3 months following the termination of this training. While performance returned to baseline, muscle mass remained elevated by 17% and a shift in distribution to larger muscle fibers persisted. A 16% greater total RNA and heightened mRNA levels of ribosomal protein S6 kinases implicated preserved transcriptional output and ribosomal content. Remodeling of muscle fiber nuclei was consistent with these findings - increased nuclear number and a distribution shift to a more circular nuclear shape. These findings indicate that muscle mass detrains at a slower rate than performance and implicates multiple forms of myonuclear remodeling in muscle memory.}, keywords = {skeletal muscle; dorsiflexor muscles; stretch-shortening contractions; dynamometer}, year = {2022}, eissn = {2051-817X} } @article{MTMT:33200864, title = {Comparison between Eccentric-Only and Coupled Concentric-Eccentric Contractions for Neuromuscular Fatigue and Muscle Damage}, url = {https://m2.mtmt.hu/api/publication/33200864}, author = {Ruas, C.V. and Latella, C. and Taylor, J.L. and Haff, G.G. and Nosaka, K.}, doi = {10.1249/MSS.0000000000002959}, journal-iso = {MED SCI SPORT EXER}, journal = {MEDICINE AND SCIENCE IN SPORTS AND EXERCISE}, volume = {54}, unique-id = {33200864}, issn = {0195-9131}, year = {2022}, eissn = {1530-0315}, pages = {1635-1646} } @article{MTMT:32721157, title = {Cerebral, cardiac and skeletal muscle stress associated with a series of static and dynamic apnoeas}, url = {https://m2.mtmt.hu/api/publication/32721157}, author = {Elia, Antonis and Woods, David R. and Barlow, Matthew J. and Lees, Matthew J. and O'Hara, John P.}, doi = {10.1111/sms.14067}, journal-iso = {SCAND J MED SCI SPOR}, journal = {SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS}, volume = {32}, unique-id = {32721157}, issn = {0905-7188}, abstract = {Purpose This study sought to explore, for the first time, the effects of repeated maximal static and dynamic apnoeic attempts on the physiological milieu by assessing cerebral, cardiac and striatal muscle stress-related biomarkers in a group of elite breath-hold divers (EBHD). Methods Sixteen healthy males were recruited (EBHD = 8; controls = 8). On two separate occasions, EBHD performed two sets of five repeated maximal static apnoeas (STA) or five repeated maximal dynamic apnoeas (DYN). Controls performed a static eupnoeic protocol to negate any effects of water immersion and diurnal variation on haematology (CTL). Venous blood samples were drawn at 30, 90, and 180 min after each protocol to determine S100 beta, neuron-specific enolase (NSE), myoglobin, and high sensitivity cardiac troponin T (hscTNT) concentrations. Results S100 beta and myoglobin concentrations were elevated following both apnoeic interventions (p p <= 0.028, respectively) but not after CTL (p >= 0.348). S100 beta increased from baseline (0.024 +/- 0.005 mu g/L) at 30 (STA, +149%, p < 0.001; DYN, +166%, p < 0.001) and 90 min (STA, +129%, p < 0.001; DYN, +132%, p = 0.008) following the last apnoeic repetition. Myoglobin was higher than baseline (22.3 +/- 2.7 ng/ml) at 30 (+42%, p = 0.04), 90 (+64%, p < 0.001) and 180 min (+49%, p = 0.013) post-STA and at 90 min (+63%, p = 0.016) post-DYN. Post-apnoeic S100 beta and myoglobin concentrations were higher than CTL (STA, p < 0.001; DYN, p <= 0.004). NSE and hscTNT did not change from basal concentrations after the apnoeic (p >= 0.146) nor following the eupnoeic (p >= 0.553) intervention. Conclusions This study suggests that a series of repeated maximal static and dynamic apnoeas transiently disrupt the blood-brain barrier and instigate muscle injury but do not induce neuronal-parenchymal damage or myocardial damage.}, keywords = {PROTEIN; MARKER; DAMAGE; Myoglobin; BRAIN-BARRIER PERMEABILITY; cardiac troponin; Neuron-specific enolase; apnoea; Hypoxia-reoxygenation; diving; BREATH-HOLD; Oxidative stress; Hypoxaemia; BREATH-HOLD DIVERS}, year = {2021}, eissn = {1600-0838}, pages = {233-241}, orcid-numbers = {Elia, Antonis/0000-0002-5991-0733; Lees, Matthew J./0000-0003-1422-0154} } @article{MTMT:32316663, title = {Aging and Recovery After Resistance-Exercise-Induced Muscle Damage: Current Evidence and Implications for Future Research}, url = {https://m2.mtmt.hu/api/publication/32316663}, author = {Fernandes, John F. T. and Lamb, Kevin L. and Norris, Jonathan P. and Moran, Jason and Drury, Benjamin and Borges, Nattai R. and Twist, Craig}, doi = {10.1123/japa.2020-0201}, journal-iso = {J AGING PHYS ACTIV}, journal = {JOURNAL OF AGING AND PHYSICAL ACTIVITY}, volume = {29}, unique-id = {32316663}, issn = {1063-8652}, abstract = {Aging is anecdotally associated with a prolonged recovery from resistance training, though current literature remains equivocal. This brief review considers the effects of resistance training on indirect markers of muscle damage and recovery (i.e., muscle soreness, blood markers, and muscle strength) in older males. With no date restrictions, four databases were searched for articles relating to aging, muscle damage, and recovery. Data from 11 studies were extracted for review. Of these, four reported worse symptoms in older compared with younger populations, while two have observed the opposite, and the remaining studies (n = 6) proposed no differences between age groups. It appears that resistance training can be practiced in older populations without concern for impaired recovery. To improve current knowledge, researchers are urged to utilize more ecologically valid muscledamaging bouts and investigate the mechanisms which underpin the recovery of muscle soreness and strength after exercise in older populations.}, keywords = {fatigue; muscle strength; Sarcopenia; muscle soreness; dynapenia}, year = {2021}, eissn = {1543-267X}, pages = {544-551}, orcid-numbers = {Moran, Jason/0000-0001-7452-6855} } @article{MTMT:32316662, title = {Protective and Recovery Effects of Resveratrol Supplementation on Exercise Performance and Muscle Damage following Acute Plyometric Exercise}, url = {https://m2.mtmt.hu/api/publication/32316662}, author = {Huang, Chi-Chang and Lee, Mon-Chien and Ho, Chin-Shan and Hsu, Yi-Ju and Ho, Chien-Chang and Kan, Nai-Wen}, doi = {10.3390/nu13093217}, journal-iso = {NUTRIENTS}, journal = {NUTRIENTS}, volume = {13}, unique-id = {32316662}, abstract = {Plyometric exercise (PE) is an effective training method to increase muscle mass and strength. However, excessive or inappropriate conditions might cause exercise-induced muscle damage (EIMD). Resveratrol (RES) is a natural polyphenol plant antitoxin, which improves exercise performance, and exhibits anti-oxidation, anti-inflammatory, and anti-cancer effects. Therefore, this study investigated the effect of RES supplementation on the recovery of muscle damage, inflammation, soreness, muscle power, and anaerobic performance following plyometric-exercise-induced muscle damage (PEIMD). The present study was a double-blind, placebo-controlled research trial. Thirty-six young, untrained males were enrolled into the placebo (n = 12), RES-500 (500 mg RES/day, n = 12), or RES-1000 (1000 mg RES/day, n = 12) group by a jumping height-counterbalanced grouping design. At baseline, to pre-PEIMD, supplements were pre-loaded 7 days before they conducted PEIMD, and the exercise performance, delayed-onset muscle soreness (DOMS) and muscle damage biomarkers were measured over the experimental period at baseline, pre-PEIMD, and post-PEIMD at 2, 24, 48, and 72 h. As a result, we found that, at 72 h post-EIMD, the force peak (FP) and rate of force development (RFD) of the counter movement jump (CMJ) in RES groups showed no significant difference compared to that at baseline but was significantly greater than the placebo group. In the Wingate anaerobic test (WAnT), supplementation in the RES group had a better recovery effect on the relative peak power (RPP), relative mean power (RMP) and fatigue index (FI) (p < 0.05), especially in the high-dose group. For the detection of muscle pain after PEIMD, the RES supplement group was significantly better than the placebo group (p < 0.05). In addition, for muscle damage indexes, such as creatine kinase (CK) and lactate dehydrogenase (LDH), after PEIMD, supplementation with RES could significantly reduce and accelerate recovery (p < 0.05). In addition, the blood biochemical indicators of blood count, liver function, and kidney function showed that RES will not cause adverse risks to the human body. Our results suggest that replenishing RES in advance could effectively reduce muscle pain, increase exercise performance, and decrease muscle damage indicators caused by PEIMD, and the recovery was faster. Therefore, plyometric exercises combined with suitable RES supplementation could be an effective candidate for controlling muscle damage, improving physical adaption, and recovering anaerobic capacity.}, keywords = {RESVERATROL; plyometric exercise-induced muscle damage (PEIMD); counter movement jump (CMJ); Wingate anaerobic test (WAnT); pressure pain threshold (PPT)}, year = {2021}, eissn = {2072-6643} } @article{MTMT:32478847, title = {Preliminary Investigations Into the Effect of Exercise-Induced Muscle Damage on Systemic Extracellular Vesicle Release in Trained Younger and Older Men}, url = {https://m2.mtmt.hu/api/publication/32478847}, author = {Kyriakidou, Y. and Cooper, I. and Kraev, I. and Lange, S. and Elliott, B.T.}, doi = {10.3389/fphys.2021.723931}, journal-iso = {FRONT PHYSIOL}, journal = {FRONTIERS IN PHYSIOLOGY}, volume = {12}, unique-id = {32478847}, abstract = {Background: Exercise-induced muscle damage (EIMD) results in transient muscle inflammation, strength loss, and muscle soreness and may cause subsequent exercise avoidance. Research has recently proven that skeletal muscle can also release extracellular vesicles (EVs) into the circulation following a bout of exercise. However, EV’s potential role, including as a biomarker, in the response to eccentric resistance exercise stimulus remains unclear. Methods: Twelve (younger, n=7, 27.0±1.5years and older, n=5, 63.0±1.0years) healthy, physically active males, undertaking moderate, regular physical activity (3–5 times per week) performed a unilateral high intensity eccentric exercise protocol. Venous plasma was collected for assessment of EVs and creatine kinase (CK) prior to EIMD, immediately after EIMD, and 1–72h post-EIMD, and maximal voluntary isometric contraction (MVIC) and delayed onset muscle soreness (DOMS) were assessed at all time points, except 1 and 2h post-EIMD. Results: A significant effect of both time (p=0.005) and group (p<0.001) was noted for MVIC, with younger participants’ MVIC being higher throughout. Whilst a significant increase was observed in DOMS in the younger group (p=0.014) and in the older group (p=0.034) following EIMD, no significant differences were observed between groups. CK was not different between age groups but was altered following the EIMD (main effect of time p=0.026), with increased CK seen immediately post-, at 1 and 2h post-EIMD. EV count tended to be lower in older participants at rest, relative to younger participants (p=0.056), whilst EV modal size did not differ between younger and older participants pre-EIMD. EIMD did not substantially alter EV modal size or EV count in younger or older participants; however, the alteration in EV concentration (ΔCount) and EV modal size (ΔMode) between post-EIMD and pre-EIMD negatively associated with CK activity. No significant associations were noted between MVIC or DOMS and either ΔCount or ΔMode of EVs at any time point. Conclusion: These findings suggest that profile of EV release, immediately following exercise, may predict later CK release and play a role in the EIMD response. Exercise-induced EV release profiles may therefore serve as an indicator for subsequent muscle damage. © Copyright © 2021 Kyriakidou, Cooper, Kraev, Lange and Elliott.}, keywords = {Inflammation; RECOVERY; strength; MUSCLE DAMAGE; ECCENTRIC EXERCISE; Ageing; Extracellular vesicles; delayed onset muscle soreness}, year = {2021}, eissn = {1664-042X} } @article{MTMT:32080084, title = {Evaluation of the Efficacy of Supplementation with Planox® Lemon Verbena Extract in Improving Oxidative Stress and Muscle Damage: A Double-Blind Controlled Trial}, url = {https://m2.mtmt.hu/api/publication/32080084}, author = {Lee, Mon-Chien and Hsu, Yi-Ju and Ho, Chin-Shan and Chang, Chun-Hao and Liu, Ching-Wen and Huang, Chi-Chang and Chiang, Wen-Dee}, doi = {10.7150/ijms.60726}, journal-iso = {INT J MED SCI}, journal = {INTERNATIONAL JOURNAL OF MEDICAL SCIENCES}, volume = {18}, unique-id = {32080084}, issn = {1449-1907}, year = {2021}, eissn = {1449-1907}, pages = {2641-2652} } @article{MTMT:31689857, title = {Changes in Urinary Titin Fragment in Response to Different Types of Dynamic Eccentric Exercises}, url = {https://m2.mtmt.hu/api/publication/31689857}, author = {Lee, Minjung and Goral, Kamil and Flis, DamianJ and Skrobot, Wojciech and Cieminski, Karol and Olek, RobertA and Akimoto, Takayuki and Ziolkowski, Wieslaw}, doi = {10.1055/a-1273-8082}, journal-iso = {INT J SPORTS MED}, journal = {INTERNATIONAL JOURNAL OF SPORTS MEDICINE}, volume = {42}, unique-id = {31689857}, issn = {0172-4622}, abstract = {The urinary level of the titin fragment has been considered a non-invasive and sensitive biomarker for muscle damage in clinical cases. However, there is little evidence regarding changes in the urinary titin fragment in response to exercise-induced muscle damage. In this study, we aimed to investigate whether the urinary titin fragment reflects the magnitude of muscle damage induced by two lower-limb eccentric exercises. In this study, healthy young male subjects performed drop jump (n=9) and eccentric ergometer exercise (n=9). Blood and urine samples were collected at various time points before and after the exercises. Although perceived muscle soreness assessed by sit-to-stand tasks was increased at 24h and 48h after both drop jump and the eccentric ergometer exercise groups, the pressure pain threshold was not changed. Changes of the urinary titin fragment, plasma myomesin 3 fragments, creatine kinase (CK), and myoglobin (Mb) after the eccentric exercises were increased but not statistically significant. Meanwhile, we found that the changes in the urinary titin fragment levels in response to both drop jump and the eccentric ergometer exercise were correlated with those of plasma CK and Mb levels. These results provide evidence that the urinary titin fragment level is a non-invasive biomarker reflecting the magnitude of eccentric exercise-induced muscle damage.}, keywords = {TITIN; Biomarkers; MUSCLE DAMAGE; ECCENTRIC EXERCISE; connectin}, year = {2020}, eissn = {1439-3964}, pages = {432-440} } @article{MTMT:31908339, title = {Exercise-Induced Muscle Damage and Cardiac Stress During a Marathon Could be Associated with Dietary Intake During the Week Before the Race}, url = {https://m2.mtmt.hu/api/publication/31908339}, author = {Mielgo-Ayuso, Juan and Calleja-González, Julio and Refoyo, Ignacio and León-Guereño, Patxi and Cordova, Alfredo and Del Coso, Juan}, doi = {10.3390/nu12020316}, journal-iso = {NUTRIENTS}, journal = {NUTRIENTS}, volume = {12}, unique-id = {31908339}, year = {2020}, eissn = {2072-6643}, orcid-numbers = {Mielgo-Ayuso, Juan/0000-0002-6554-4602; Calleja-González, Julio/0000-0003-2575-7168; León-Guereño, Patxi/0000-0003-2772-9128; Del Coso, Juan/0000-0002-5785-984X} } @article{MTMT:31908342, title = {Efficient and Robust Detection of Local Impedance Changes Using Selected Electrical Excitation Conditions}, url = {https://m2.mtmt.hu/api/publication/31908342}, author = {Yoshimoto, Shunsuke and Ikemoto, Naoki and Ishizuka, Hiroki and Ikeda, Sei and Kuroda, Yoshihiro and Oshiro, Osamu}, doi = {10.1109/ACCESS.2020.3037167}, journal-iso = {IEEE ACCESS}, journal = {IEEE ACCESS}, volume = {8}, unique-id = {31908342}, issn = {2169-3536}, year = {2020}, eissn = {2169-3536}, pages = {205778-205787}, orcid-numbers = {Yoshimoto, Shunsuke/0000-0001-8583-6699; Ikeda, Sei/0000-0002-8829-1580; Kuroda, Yoshihiro/0000-0003-4511-8195} }