@mastersthesis{MTMT:33606840,
	title = {Hypersensitivity to polymer-coated nanomedicines : mechanism, prediction and prevention},
	url = {https://m2.mtmt.hu/api/publication/33606840},
	isbn = {9789036554633},
	author = {Fülöp, Tamás},
	doi = {10.3990/1.9789036554633},
	unique-id = {33606840},
	year = {2023},
	orcid-numbers = {Fülöp, Tamás/0000-0003-2889-1370}
}

@article{MTMT:34424489,
	title = {Inhibition of acute complement responses towards bolus-injected nanoparticles using targeted short-circulating regulatory proteins},
	url = {https://m2.mtmt.hu/api/publication/34424489},
	author = {Li, Y. and Jacques, S. and Gaikwad, H. and Wang, G. and Banda, N.K. and Holers, V.M. and Scheinman, R.I. and Tomlinson, S. and Moghimi, S.M. and Simberg, D.},
	doi = {10.1038/s41565-023-01514-z},
	journal-iso = {NAT NANOTECHNOL},
	journal = {NATURE NANOTECHNOLOGY},
	unique-id = {34424489},
	issn = {1748-3387},
	year = {2023},
	eissn = {1748-3395}
}

@article{MTMT:32785549,
	title = {Cancer cell membrane-derived nanoparticles block the expression of immune checkpoint proteins on cancer cells and coordinate modulatory activity on immunosuppressive macrophages},
	url = {https://m2.mtmt.hu/api/publication/32785549},
	author = {Comparetti, E.J. and Lins, P.M.P. and Quitiba, J. and Zucolotto, V.},
	doi = {10.1002/jbm.a.37387},
	journal-iso = {J BIOMED MATER RES A},
	journal = {JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A},
	volume = {110},
	unique-id = {32785549},
	issn = {1549-3296},
	year = {2022},
	eissn = {1552-4965},
	pages = {1499-1511}
}

@article{MTMT:32611937,
	title = {Immunomodulatory properties of nanostructured systems for cancer therapy},
	url = {https://m2.mtmt.hu/api/publication/32611937},
	author = {Comparetti, E.J. and Ferreira, N.N. and Ferreira, L.M.B. and Kaneno, R. and Zucolotto, V.},
	doi = {10.1002/jbm.a.37359},
	journal-iso = {J BIOMED MATER RES A},
	journal = {JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A},
	volume = {110},
	unique-id = {32611937},
	issn = {1549-3296},
	year = {2022},
	eissn = {1552-4965},
	pages = {1166-1181}
}

@article{MTMT:33187173,
	title = {Lessons learned from immunological characterization of nanomaterials at the Nanotechnology Characterization Laboratory},
	url = {https://m2.mtmt.hu/api/publication/33187173},
	author = {Dobrovolskaia, Marina A.},
	doi = {10.3389/fimmu.2022.984252},
	journal-iso = {FRONT IMMUNOL},
	journal = {FRONTIERS IN IMMUNOLOGY},
	volume = {13},
	unique-id = {33187173},
	issn = {1664-3224},
	year = {2022},
	eissn = {1664-3224}
}

@article{MTMT:32552896,
	title = {To PEGylate or not to PEGylate: Immunological properties of nanomedicine's most popular component, polyethylene glycol and its alternatives},
	url = {https://m2.mtmt.hu/api/publication/32552896},
	author = {Shi, D. and Beasock, D. and Fessler, A. and Szebeni, János and Ljubimova, J.Y. and Afonin, K.A. and Dobrovolskaia, M.A.},
	doi = {10.1016/j.addr.2021.114079},
	journal-iso = {ADV DRUG DELIV REV},
	journal = {ADVANCED DRUG DELIVERY REVIEWS},
	volume = {180},
	unique-id = {32552896},
	issn = {0169-409X},
	year = {2022},
	eissn = {1872-8294}
}

@article{MTMT:31954633,
	title = {Mechanistic investigation of thermosensitive liposome immunogenicity and understanding the drivers for circulation half-life: A polyethylene glycol versus 1,2-dipalmitoyl-sn-glycero-3-phosphodiglycerol study},
	url = {https://m2.mtmt.hu/api/publication/31954633},
	author = {Lokerse, W.J.M. and Lazarian, A. and Kleinhempel, A. and Petrini, M. and Schwarz, P. and Hossann, M. and Holdt, L.M. and Mailänder, V. and Lindner, L.H.},
	doi = {10.1016/j.jconrel.2021.03.014},
	journal-iso = {J CONTROL RELEASE},
	journal = {JOURNAL OF CONTROLLED RELEASE},
	volume = {333},
	unique-id = {31954633},
	issn = {0168-3659},
	year = {2021},
	eissn = {1873-4995},
	pages = {1-15}
}

@article{MTMT:32502897,
	title = {Getting to the Core of It All: Nanocapsules to Mitigate Infusion Reactions Can Promote Hemostasis and Be a Platform for Intravenous Therapies},
	url = {https://m2.mtmt.hu/api/publication/32502897},
	author = {Maisha, N. and Rubenstein, M. and Bieberich, C.J. and Lavik, E.},
	doi = {10.1021/acs.nanolett.1c02746},
	journal-iso = {NANO LETT},
	journal = {NANO LETTERS},
	volume = {21},
	unique-id = {32502897},
	issn = {1530-6984},
	year = {2021},
	eissn = {1530-6992},
	pages = {9069-9076}
}

@article{MTMT:31864261,
	title = {Complement-mediated hypersensitivity reactions to an amphotericin B-containing lipid complex (Abelcet) in pediatric patients and anesthetized rats: Benefits of slow infusion},
	url = {https://m2.mtmt.hu/api/publication/31864261},
	author = {Milosevits, Gergely and Mészáros, Tamás and Őrfi, Erik and Bakos, Tamás and Garami, Miklós and Kovács, Gábor and Dézsi, László and Hamar, Péter and Győrffy, Balázs and Szabó, András and Szénási, Gábor and Szebeni, János},
	doi = {10.1016/j.nano.2021.102366},
	journal-iso = {NANOMED: NANOTECHNOL},
	journal = {NANOMEDICINE: NANOTECHNOLOGY BIOLOGY AND MEDICINE},
	volume = {34},
	unique-id = {31864261},
	issn = {1549-9634},
	year = {2021},
	eissn = {1549-9642},
	orcid-numbers = {Milosevits, Gergely/0000-0002-5897-9472; Őrfi, Erik/0000-0002-2190-0708; Bakos, Tamás/0000-0002-0569-8343; Garami, Miklós/0000-0003-4298-2746; Kovács, Gábor/0000-0001-9924-1645; Dézsi, László/0000-0002-4190-9793; Hamar, Péter/0000-0002-1095-3564; Győrffy, Balázs/0000-0002-5772-3766; Szabó, András/0000-0001-8320-4946; Szénási, Gábor/0000-0002-7350-6091}
}

@article{MTMT:32152029,
	title = {Spotlight on the protein corona of liposomes},
	url = {https://m2.mtmt.hu/api/publication/32152029},
	author = {Onishchenko, N. and Tretiakova, D. and Vodovozova, E.},
	doi = {10.1016/j.actbio.2021.07.074},
	journal-iso = {ACTA BIOMATER},
	journal = {ACTA BIOMATERIALIA},
	volume = {134},
	unique-id = {32152029},
	issn = {1742-7061},
	year = {2021},
	eissn = {1878-7568},
	pages = {57-78}
}

@article{MTMT:31661709,
	title = {The Critical Choice of Animal Models in Nanomedicine Safety Assessment: A Lesson Learned From Hemoglobin-Based Oxygen Carriers},
	url = {https://m2.mtmt.hu/api/publication/31661709},
	author = {Bedőcs, Péter and Szebeni, János},
	doi = {10.3389/fimmu.2020.584966},
	journal-iso = {FRONT IMMUNOL},
	journal = {FRONTIERS IN IMMUNOLOGY},
	volume = {11},
	unique-id = {31661709},
	issn = {1664-3224},
	abstract = {Intravenous injection of nanopharmaceuticals can induce severe hypersensitivity reactions (HSRs) resulting in anaphylactoid shock in a small percentage of patients, a phenomenon explicitly reproducible in pigs. However, there is a debate in the literature on whether the pig model of HSRs can be used as a safety test for the prediction of severe adverse reactions in humans. Given the importance of using appropriate animal models for toxicity/safety testing, the choice of the right species and model is a critical decision. In order to facilitate the decision process and to expand the relevant information regarding the pig or no pig dilemma, this review examines an ill-fated clinical development program conducted by Baxter Corporation in the United States 24 years ago, when HemeAssist, an αα (diaspirin) crosslinked hemoglobin-based O2 carrier (HBOC) was tested in trauma patients. The study showed increased mortality in the treatment group relative to controls and had to be stopped. This disappointing result had far-reaching consequences and contributed to the setback in blood substitute research ever since. Importantly, the increased mortality of trauma patients was predicted in pig experiments conducted by US Army scientists, yet they were considered irrelevant to humans. Here we draw attention to that the underlying cause of hemoglobin-induced aggravation of hemorrhagic shock and severe HSRs have a common pathomechanism: cardiovascular distress due to vasoconstrictive effects of hemoglobin (Hb) and reactogenic nanomedicines, manifested, among others, in pulmonary hypertension. The main difference is that in the case of Hb this effect is due to NO-binding, while nanomedicines can trigger the release of proinflammatory mediators. Because of the higher sensitivity of cloven-hoof animals to this kind of cardiopulmonary distress compared to rodents, these reactions can be better reproduced in pigs than in murine or rat models. When deciding on the battery of tests and the appropriate models to identify the potential hazard for nanomedicine-induced severe HSR, the pros and cons of the various species must be considered carefully.},
	year = {2020},
	eissn = {1664-3224}
}

@article{MTMT:31279240,
	title = {Human Clinical Relevance of the Porcine Model of Pseudoallergic Infusion Reactions},
	url = {https://m2.mtmt.hu/api/publication/31279240},
	author = {Szebeni, János and Bawa, Raj},
	doi = {10.3390/biomedicines8040082},
	journal-iso = {BIOMEDICINES},
	journal = {BIOMEDICINES},
	volume = {8},
	unique-id = {31279240},
	year = {2020},
	eissn = {2227-9059}
}