TY  - JOUR
AU  - Curto, M. Ángeles
AU  - Butassi, Estefanía
AU  - Ribas, Juan C.
AU  - Svetaz, Laura A.
AU  - Cortés, Juan C.G.
TI  - Natural products targeting the synthesis of β(1,3)-D-glucan and chitin of the fungal cell wall. Existing drugs and recent findings
JF  - PHYTOMEDICINE: INTERNATIONAL JOURNAL OF PHYTOTHERAPY AND PHYTOPHARMACOLOGY
J2  - PHYTOMEDICINE
VL  - 88
PY  - 2021
SN  - 0944-7113
DO  - 10.1016/j.phymed.2021.153556
UR  - https://m2.mtmt.hu/api/publication/32173088
ID  - 32173088
N1  - Instituto de Biología Funcional y Genómica and Departamento de Microbiología y Genética, Consejo Superior de Investigaciones Científicas (CSIC)/Universidad de Salamanca, Salamanca, Spain            
            Área Farmacognosia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, 2000 Rosario, Argentina            
            Export Date: 09 January 2024; Cited By: 21; Correspondence Address: L.A. Svetaz; Área Farmacognosia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, 2000 Rosario, Argentina; email: lsvetaz@fbioyf.unr.edu.ar; CODEN: PYTOE
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Gowda, D. V
AU  - Afrasim, M.
AU  - Meenakshi, S. I
AU  - Manohar, M.
AU  - Hemalatha, S.
AU  - Siddaramaiah, H.
AU  - Sathishbabu, P.
AU  - Rizvi, S. M. Danish
AU  - Hussain, T.
AU  - Kamal, M. A.
TI  - A Paradigm Shift in the Development of Anti-Candida Drugs
JF  - CURRENT TOPICS IN MEDICINAL CHEMISTRY
J2  - CURR TOP MED CHEM
VL  - 19
PY  - 2019
IS  - 28
SP  - 2610
EP  - 2628
PG  - 19
SN  - 1568-0266
DO  - 10.2174/1568026619666191029145209
UR  - https://m2.mtmt.hu/api/publication/31285555
ID  - 31285555
N1  - Funding Agency and Grant Number: DBT, Government of India, Delhi [BT/PR20803/TRM/120/118/2016]
            Funding text: The author(s) are grateful for the financial support received from DBT, Government of India, Delhi through project BT/PR20803/TRM/120/118/2016 Dated 14/03/2018.
AB  - Background: The considerable increase in the incidence of Candida infection in recent times has prompted the use of numerous antifungal agents, which has resulted in the development of resistance towards various antifungal agents. With rising Candida infections, the need for design and development of novel antifungal agents is in great demand. However, new therapeutic approaches are very essential in preventing the mortality rate and improving the patient outcome in those suffering from Candida infections. Objective: The present review objective is to describe the burden, types of Candidiasis, mechanism of action of antifungal agents and its resistance and the current novel approaches used to combat candidiasis. Methods: We have collected and analyzed 135 different peer-reviewed literature studies pertinent to candidiasis. In this review, we have compiled the major findings from these studies. Results and Conclusion: The review describes the concerns related to candidiasis, its current treatment strategy, resistance mechanisms and imminent ways to tackle the problem. The review explored that natural plant extracts and essential oils could act as sources of newer therapeutic agents, however, the focus was on novel strategies, such as combinational therapy, new antibodies, utilization of photodynamic therapy and adaptive transfer primed immune cells with emphasis on the development of effective vaccination.
LA  - English
DB  - MTMT
ER  -