@article{MTMT:34423874,
	title = {Dots and spots: A retrospective review of T2-hyperintense white matter lesions in pediatric patients with and without headache},
	url = {https://m2.mtmt.hu/api/publication/34423874},
	author = {Ackley, E. and Asamoah, P. and Mirsky, D. and White, C. and Maloney, J. and Stence, N. and Silveira, L. and Yonker, M. and Neuberger, I.},
	doi = {10.1111/head.14503},
	journal-iso = {HEADACHE},
	journal = {HEADACHE},
	volume = {63},
	unique-id = {34423874},
	issn = {0017-8748},
	year = {2023},
	eissn = {1526-4610},
	pages = {611-620}
}

@article{MTMT:34242920,
	title = {Cortical spreading depolarization-induced constriction of penetrating arteries can cause watershed ischemia: A potential mechanism for white matter lesions},
	url = {https://m2.mtmt.hu/api/publication/34242920},
	author = {Donmez-Demir, Buket and Yemisci, Muge and Uruk, Gokhan and Soylemezoglu, Figen and Bolbos, Radu and Kazmi, Shams and Dalkara, Turgay},
	doi = {10.1177/0271678X231186959},
	journal-iso = {J CEREBR BLOOD F MET},
	journal = {JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM},
	unique-id = {34242920},
	issn = {0271-678X},
	abstract = {Periventricular white matter lesions (WMLs) are common MRI findings in migraine with aura (MA). Although hemodynamic disadvantages of vascular supply to this region create vulnerability, the pathophysiological mechanisms causing WMLs are unclear. We hypothesize that prolonged oligemia, a consequence of cortical spreading depolarization (CSD) underlying migraine aura, may lead to ischemia/hypoxia at hemodynamically vulnerable watershed zones fed by long penetrating arteries (PAs). For this, we subjected mice to KCl-triggered single or multiple CSDs. We found that post-CSD oligemia was significantly deeper at medial compared to lateral cortical areas, which induced ischemic/hypoxic changes at watershed areas between the MCA/ACA, PCA/anterior choroidal and at the tip of superficial and deep PAs, as detected by histological and MRI examination of brains 2-4 weeks after CSD. BALB-C mice, in which MCA occlusion causes large infarcts due to deficient collaterals, exhibited more profound CSD-induced oligemia and were more vulnerable compared to Swiss mice such that a single CSD was sufficient to induce ischemic lesions at the tip of PAs. In conclusion, CSD-induced prolonged oligemia has potential to cause ischemic/hypoxic injury at hemodynamically vulnerable brain areas, which may be one of the mechanisms underlying WMLs located at the tip of medullary arteries seen in MA patients.},
	keywords = {MIGRAINE; White matter lesions; CORTICAL SPREADING DEPOLARIZATION; watershed ischemia; penetrating artery},
	year = {2023},
	eissn = {1559-7016},
	orcid-numbers = {Yemisci, Muge/0000-0002-1528-1998}
}

@article{MTMT:34207248,
	title = {The volume of the thalamus and hippocampus in a right-handed female episodic migraine group},
	url = {https://m2.mtmt.hu/api/publication/34207248},
	author = {He, Mingchen and Kis-Jakab, Gréta and Komáromy, Hedvig and Perlaki, Gábor and Orsi, Gergely and Bosnyák, Edit and Rozgonyi, Renáta and John, Flóra and Trauninger, Anita and Eklicsné Lepenye, Katalin and Pfund, Zoltán},
	doi = {10.3389/fneur.2023.1254628},
	journal-iso = {FRONT NEUR},
	journal = {FRONTIERS IN NEUROLOGY},
	volume = {14},
	unique-id = {34207248},
	issn = {1664-2295},
	year = {2023},
	eissn = {1664-2295}
}

@article{MTMT:33765822,
	title = {White Matter Lesions Identified by Magnetic Resonance in Women with Migraine: A Volumetric Analysis and Clinical Correlations},
	url = {https://m2.mtmt.hu/api/publication/33765822},
	author = {Silva, N.D.O. and Maciel, N.M. and Nather, Jr J.C. and Carvalho, G.F. and Pinheiro, C.F. and Bigal, M.E. and Santos, A.C.D. and Bevilaqua-Grossi, D. and Dach, F.},
	doi = {10.3390/diagnostics13040799},
	journal-iso = {DIAGNOSTICS},
	journal = {DIAGNOSTICS},
	volume = {13},
	unique-id = {33765822},
	issn = {2075-4418},
	year = {2023},
	eissn = {2075-4418}
}

@article{MTMT:33008513,
	title = {Central Vein Sign Profile of Newly Developing Lesions in Multiple Sclerosis A 3-Year Longitudinal Study},
	url = {https://m2.mtmt.hu/api/publication/33008513},
	author = {Al-Louzi, Omar and Letchuman, Vijay and Manukyan, Sargis and Beck, Erin S. and Roy, Snehashis and Ohayon, Joan and Pham, Dzung L. and Cortese, Irene and Sati, Pascal and Reich, Daniel S.},
	doi = {10.1212/NXI.0000000000001120},
	journal-iso = {NEUROL-NEUROIMMUNOL},
	journal = {NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION},
	volume = {9},
	unique-id = {33008513},
	issn = {2332-7812},
	abstract = {Background and ObjectivesThe central vein sign (CVS), a central linear hypointensity within lesions on T2*-weighted imaging, has been established as a sensitive and specific biomarker for the diagnosis of multiple sclerosis (MS). However, the CVS has not yet been comprehensively studied in newly developing MS lesions. We aimed to identify the CVS profiles of new white matter lesions in patients with MS followed over time and investigate demographic and clinical risk factors associated with new CVS+ or CVS- lesion development.MethodsIn this retrospective longitudinal cohort study, adults from the NIH MS Natural History Study were considered for inclusion. Participants with new T2 or enhancing lesions were identified through review of the radiology report and/or longitudinal subtraction imaging. Each new lesion was evaluated for the CVS. Clinical characteristics were identified through chart review.ResultsA total of 153 adults (95 relapsing-remitting MS, 27 secondary progressive MS, 16 primary progressive MS, 5 clinically isolated syndrome, and 10 healthy; 67% female) were included. Of this cohort, 96 had at least 1 new T2 or contrast-enhancing lesion during median 3.1 years (Q1-Q3: 0.7-6.3) of follow-up; lesions eligible for CVS evaluation were found in 62 (65%). Of 233 new CVS-eligible lesions, 159 (68%) were CVS+, with 30 (48%) individuals having only CVS+, 12 (19%) only CVS-, and 20 (32%) both CVS+ and CVS- lesions. In gadolinium-enhancing (Gd+) lesions, the CVS+ percentage increased from 102/152 (67%) at the first time point where the lesion was observed, to 92/114 (82%) after a median follow-up of 2.8 years. Younger age (OR = 0.5 per 10-year increase, 95% CI = 0.3-0.8) and higher CVS+ percentage at baseline (OR = 1.4 per 10% increase, 95% CI = 1.1-1.9) were associated with increased likelihood of new CVS+ lesion development.DiscussionIn a cohort of adults with MS followed over a median duration of 3 years, most newly developing T2 or enhancing lesions were CVS+ (68%), and nearly half (48%) developed new CVS+ lesions only. Importantly, the effects of edema and T2 signal changes can obscure small veins in Gd+ lesions; therefore, caution and follow-up is necessary when determining their CVS status.Classification of EvidenceThis study provides Class III evidence that younger age and higher CVS+ percentage at baseline are associated with new CVS+ lesion development.},
	year = {2022},
	eissn = {2332-7812},
	orcid-numbers = {Al-Louzi, Omar/0000-0003-2260-5660; Letchuman, Vijay/0000-0001-6594-596X; Roy, Snehashis/0000-0002-7997-3993}
}

@article{MTMT:33177539,
	title = {Cerebral Hemodynamics, Right-to-Left Shunt and White Matter Hyperintensities in Patients with Migraine with Aura, Young Stroke Patients and Controls},
	url = {https://m2.mtmt.hu/api/publication/33177539},
	author = {Brunelli, Nicoletta and Altamura, Claudia and Mallio, Carlo A. and Lo Vullo, Gianguido and Marcosano, Marilena and Bach-Pages, Marcel and Zobel, Bruno Beomonte and Quattrocchi, Carlo Cosimo and Vernieri, Fabrizio},
	doi = {10.3390/ijerph19148575},
	journal-iso = {INT J ENV RES PUB HE},
	journal = {INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH},
	volume = {19},
	unique-id = {33177539},
	issn = {1661-7827},
	abstract = {Background: Migraine with aura (MA) patients present an increased risk of cerebrovascular events. However, whether these patients present an increased white matter hyperintensities (WMHs) load compared to the general population is still under debate. Our study aimed to evaluate the relationship between cerebral hemodynamics, right-to-left shunt (RLS) and WMHs in MA patients, young patients with cryptogenic stroke or motor transient ischemic attack (TIA) and controls. Methods: We enrolled 30 MA patients, 20 young (<60 years) patients with cryptogenic stroke/motor TIA, and 10 controls. All the subjects underwent a transcranial Doppler bubble test to detect RLS and cerebral hemodynamics assessed by the breath holding index (BHI) for the middle (MCA) and posterior (PCA) cerebral arteries. Vascular risk factors were collected. The WMHs load on FLAIR MRI sequences was quantitatively assessed. Results: The stroke/TIA patients presented a higher prevalence of RLS (100%) compared with the other groups (p < 0.001). The MA patients presented a higher BHI compared with the other groups in the PCA (p = 0.010) and higher RLS prevalence (60%) than controls (30%) (p < 0.001). The WMHs load did not differ across groups. BHI and RLS were not correlated to the WMHs load in the groups. Conclusions: A preserved or more reactive cerebral hemodynamics and the presence of a RLS are likely not involved in the genesis of WMHs in MA patients. A higher BHI may counteract the risk related to their higher prevalence of RLS. These results need to be confirmed by further studies to be able to effectively identify the protective role of cerebral hemodynamics in the increased RLS frequency in MA patients.},
	keywords = {Cerebral hemodynamics; White matter hyperintensities; Right-to-left shunt},
	year = {2022},
	eissn = {1660-4601},
	orcid-numbers = {Brunelli, Nicoletta/0000-0002-8590-9015; Altamura, Claudia/0000-0002-5934-5535; Mallio, Carlo A./0000-0002-0149-0801}
}

@article{MTMT:33226926,
	title = {Association of LTA and SOD Gene Polymorphisms with Cerebral White Matter Hyperintensities in Migraine Patients},
	url = {https://m2.mtmt.hu/api/publication/33226926},
	author = {Ferroni, Patrizia and Palmirotta, Raffaele and Egeo, Gabriella and Aurilia, Cinzia and Valente, Maria Giovanna and Spila, Antonella and Pierallini, Alberto and Barbanti, Piero and Guadagni, Fiorella},
	doi = {10.3390/ijms232213781},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {23},
	unique-id = {33226926},
	issn = {1661-6596},
	abstract = {White matter hyperintensities (WMHs) in migraine could be related to inflammatory and antioxidant events. The aim of this study is to verify whether migraine patients with WMHs carry a genetic pro-inflammatory/pro-oxidative status. To test this hypothesis, we analyzed lymphotoxin alpha (LTA; rs2071590T and rs2844482G) and superoxide dismutase 1 (SOD1; rs2234694C) and 2 (SOD2; rs4880T) gene polymorphisms (SNPs) in 370 consecutive patients affected by episodic (EM; n = 251) and chronic (CM; n = 119) migraine and in unrelated healthy controls (n = 100). Brain magnetic resonance was available in 183/370 patients. The results obtained show that genotypes and allele frequencies for all tested SNPs did not differ between patients and controls. No association was found between single SNPs or haplotypes and sex, migraine type, cardiovascular risk factors or disorders. Conversely, the LTA rs2071590T (OR = 2.2) and the SOD1 rs2234694C (OR = 4.9) alleles were both associated with WMHs. A four-loci haplotype (TGCT haplotype: rs2071590T/rs2844482G/rs2234694C/rs4880T) was significantly more frequent in migraineurs with WMHs (7 of 38) compared to those without WMHs (4 of 134; OR = 8.7). We may, therefore, conclude by suggesting that that an imbalance between pro-inflammatory/pro-oxidative and antioxidant events in genetically predisposed individuals may influence the development of WMHs.},
	year = {2022},
	eissn = {1422-0067},
	orcid-numbers = {Ferroni, Patrizia/0000-0002-9877-8712; Palmirotta, Raffaele/0000-0002-9401-7377; Aurilia, Cinzia/0000-0002-2658-2243}
}

@article{MTMT:34776085,
	title = {Potential risk factors of persistent postural-perceptual dizziness: a pilot study},
	url = {https://m2.mtmt.hu/api/publication/34776085},
	author = {Li, L. and He, S. and Liu, H. and Pan, M. and Dai, F.},
	doi = {10.1007/s00415-021-10899-7},
	journal-iso = {J NEUROL},
	journal = {JOURNAL OF NEUROLOGY},
	volume = {269},
	unique-id = {34776085},
	issn = {0340-5354},
	year = {2022},
	eissn = {1432-1459},
	pages = {3075-3085}
}

@article{MTMT:33549008,
	title = {Magnetic resonance spectroscopy studies in migraine},
	url = {https://m2.mtmt.hu/api/publication/33549008},
	author = {Nikolova, S. and Schwedt, T.J.},
	doi = {10.1016/j.ynpai.2022.100102},
	journal-iso = {Neurobiol. Pain},
	journal = {Neurobiology of Pain},
	volume = {12},
	unique-id = {33549008},
	issn = {2452-073X},
	year = {2022}
}

@article{MTMT:32188372,
	title = {White matter hyperintensity in different migraine subtypes},
	url = {https://m2.mtmt.hu/api/publication/32188372},
	author = {Dobrynina, L.A. and Suslina, A.D. and Gubanova, M.V. and Belopasova, A.V. and Sergeeva, A.N. and Evers, S. and Gnedovskaya, E.V. and Krotenkova, M.V.},
	doi = {10.1038/s41598-021-90341-0},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {11},
	unique-id = {32188372},
	issn = {2045-2322},
	year = {2021},
	eissn = {2045-2322}
}

@article{MTMT:32010180,
	title = {White Matter Lesions in Migraine},
	url = {https://m2.mtmt.hu/api/publication/32010180},
	author = {Eikermann-Haerter, Katharina and Huang, Susie Y.},
	doi = {10.1016/j.ajpath.2021.02.007},
	journal-iso = {AM J PATHOL},
	journal = {AMERICAN JOURNAL OF PATHOLOGY},
	volume = {191},
	unique-id = {32010180},
	issn = {0002-9440},
	year = {2021},
	eissn = {1525-2191},
	pages = {1955-1962},
	orcid-numbers = {Eikermann-Haerter, Katharina/0000-0002-5059-6012}
}

@article{MTMT:32313178,
	title = {Acupuncture Modulation Effect on Pain Processing Patterns in Patients With Migraine Without Aura},
	url = {https://m2.mtmt.hu/api/publication/32313178},
	author = {Tian, Zilei and Guo, Yaoguang and Yin, Tao and Xiao, Qingqing and Ha, Guodong and Chen, Jiyao and Wang, Shuo and Lan, Lei and Zeng, Fang},
	doi = {10.3389/fnins.2021.729218},
	journal-iso = {FRONT NEUROSCI-SWITZ},
	journal = {FRONTIERS IN NEUROSCIENCE},
	volume = {15},
	unique-id = {32313178},
	issn = {1662-4548},
	abstract = {IntroductionIn this retrospective study, resting-state functional connectivity (FC) in patients with migraine was analyzed to identify potential pathological pain processing patterns and compared them to those in healthy controls (HCs). The FC patterns in patients between pre- and post-acupuncture sessions were also analyzed to determine how acupuncture affects neurological activity and pain perception during the migraine interictal period. MethodsIn total, 52 patients with migraine without aura (MwoA) and 60 HCs were recruited. Patients with migraine were given acupuncture treatment sessions for 4 weeks. As a primary observation, functional magnetic resonance images were obtained at the beginning and end of the sessions. HCs received no treatment and underwent one functional magnetic resonance imaging (fMRI) scan after enrollment. After the fMRI data were preprocessed, a region of interest (ROI)-to-ROI analysis was performed with predefined ROIs related to pain processing regions. ResultsThe first analysis showed significantly different FCs between patients with MwoA and HCs [false discovery rate corrected p-value (p-FDR) < 0.05]. The FCs were found to be mainly between the cingulate gyrus (CG) and the insular gyrus, the CG and the inferior parietal lobule (IPL), the CG and the superior frontal gyrus, and the middle frontal gyrus and the IPL. The second analysis indicated that acupuncture treatment partly restored the different FCs found in the first analysis (p-FDR < 0.05). Furthermore, subgroup analysis found different brain activity patterns in headache-intensity restored condition and headache-frequency restored condition. Lastly, the correlation analysis suggested a potential correlation between FCs and clinical symptoms (p < 0.05). ConclusionThis study suggests that pain processing is abnormal in migraine, with significantly abnormal FCs in the frontal, parietal, and limbic regions. This finding could be a typical pathological feature of migraine. Acupuncture has been identified to relieve headache symptoms in two ways: it restores the pain processing function and regulates pain perception.},
	keywords = {FMRI; migraine without aura; pain processing; functional connectivity; acupuncture; resting-state},
	year = {2021},
	eissn = {1662-453X}
}

@article{MTMT:32188373,
	title = {The association of mri findings in migraine with the headache characteristics and response to treatment},
	url = {https://m2.mtmt.hu/api/publication/32188373},
	author = {Alkhaffaf, W.H. and Naif, M.M. and Ahmed, R.N.},
	doi = {10.5281/zenodo.4487139},
	journal-iso = {REV LATINOAM HIPERTE},
	journal = {REVISTA LATINOAMERICANA DE HIPERTENSION},
	volume = {15},
	unique-id = {32188373},
	issn = {1856-4550},
	year = {2020},
	pages = {345-351}
}

@article{MTMT:31296522,
	title = {Evaluation of Non-specific Cerebral White Matter Lesions and Related Factors in Patients with Migraine with Aura},
	url = {https://m2.mtmt.hu/api/publication/31296522},
	author = {Atalar, Arife Cimen and Yalin, Osman Ozgur},
	doi = {10.4274/haseki.galenos.2019.5535},
	journal-iso = {MED BULL HASEKI},
	journal = {HASEKI TIP BULTENI / MEDICAL BULLETIN OF HASEKI},
	volume = {58},
	unique-id = {31296522},
	issn = {1302-0072},
	abstract = {Aim: Cerebral white matter hyperintensities (WMLs) are known to be observed in migraine patients but there only are a handful of studies focused on WMLs in migraine with aura (MWA). In this study, we aimed to investigate the frequency of WML and demographic and environmental factors associated with WML in patients with MWA. Methods: A total of 112 patients diagnosed with migraine were enrolled. Detailed systemic and neurological examinations, blood pressure, weight and height measurements, presence of hypertension, smoking status, clinical and demographical data and visual analog scale, allodynia symptom checklist (ASC) and migraine disability assessment scale scores were recorded. The migraine groups with and without aura were compared statistically. A logistic regression analysis was performed to analyse the risk factors for the development of WMLs. Results: Supratentorial and periventricular WMLs were more frequent in patients with MWA (p=0.008). Presence of aura and longer disease duration were independent risk factors for the development of WMLs (p=0.0020 and p=0.019, respectively). Migraine attack frequency, and ASC scores were higher in patients with MWA (p=0.005, p=0.015 and p<0.001, respectively). Conclusion: Our results show a significant increase in nonspecific WMLs in patients with MWA. A longer disease duration and presence of aura are significant risk factors for development of these lesions. Our findings warrant further research to validate our result.},
	keywords = {PREVALENCE; ASSOCIATION; ABNORMALITIES; stroke; magnetic resonance; MRI; migraine without aura; migraine with aura; HYPERINTENSITIES; CLINICAL-FEATURES; CHRONIC DAILY HEADACHE; CUTANEOUS ALLODYNIA; Cerebral white matter},
	year = {2020},
	eissn = {2147-2688},
	pages = {122-128}
}

@article{MTMT:30918249,
	title = {Two-step deep neural network for segmentation of deep white matter hyperintensities in migraineurs},
	url = {https://m2.mtmt.hu/api/publication/30918249},
	author = {Hong, J. and Park, B.-Y. and Lee, M.J. and Chung, C.-S. and Cha, J. and Park, H.},
	doi = {10.1016/j.cmpb.2019.105065},
	journal-iso = {COMPUT METH PROG BIO},
	journal = {COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE},
	volume = {183},
	unique-id = {30918249},
	issn = {0169-2607},
	year = {2020},
	eissn = {1872-7565}
}

@article{MTMT:31846244,
	title = {White matter disease and outcomes of mechanical thrombectomy for acute ischemic stroke},
	url = {https://m2.mtmt.hu/api/publication/31846244},
	author = {Mistry, E.A. and Mistry, A.M. and Mehta, T. and Arora, N. and Starosciak, A.K. and la, Rosa F.D.L.R. and Siegler, J.E. and Kasner, S.E. and Chitale, R. and Fusco, M. and Froehler, M. and Yaghi, S. and Schrag, M. and Khatri, P.},
	doi = {10.3174/AJNR.A6478},
	journal-iso = {AM J NEURORADIOL},
	journal = {AMERICAN JOURNAL OF NEURORADIOLOGY},
	volume = {41},
	unique-id = {31846244},
	issn = {0195-6108},
	year = {2020},
	eissn = {1936-959X},
	pages = {639-644}
}

@article{MTMT:31137538,
	title = {Headache intensity is associated with increased white matter lesion burden in CADASIL patients},
	url = {https://m2.mtmt.hu/api/publication/31137538},
	author = {Tábuas-Pereira, M. and Varela, R. and Beato-Coelho, J. and Maleita, D. and Ferreira, C. and d'Almeida, O.C. and Nunes, C. and Luzeiro, I. and Santo, G.C.},
	doi = {10.1016/j.jocn.2019.11.025},
	journal-iso = {J CLIN NEUROSCI},
	journal = {JOURNAL OF CLINICAL NEUROSCIENCE},
	volume = {73},
	unique-id = {31137538},
	issn = {0967-5868},
	year = {2020},
	eissn = {1532-2653},
	pages = {179-182}
}

@article{MTMT:30390795,
	title = {Influence of hemispheric white matter lesions and migraine characteristics on cortical thickness and volume},
	url = {https://m2.mtmt.hu/api/publication/30390795},
	author = {Komáromy, Hedvig and He, Mingchen and Perlaki, Gábor and Orsi, Gergely and Nagy, Szilvia Anett and Bosnyák, Edit and Kamson Olayinka, Dávid and John, Flóra and Trauninger, Anita and Pfund, Zoltán},
	doi = {10.1186/s10194-019-0959-2},
	journal-iso = {J HEADACHE PAIN},
	journal = {JOURNAL OF HEADACHE AND PAIN},
	volume = {20},
	unique-id = {30390795},
	issn = {1129-2369},
	abstract = {Migraine-related intracerebral white matter lesions (WMLs) are likely to be microvascular in nature and can be found in all hemispheric lobes. The aim of this study was to investigate migraine patients with or without WMLs to see the effects of these tissue damages on cortical thickness and volume. The role of migraine characteristics (duration of headache, attack frequency, estimated lifetime attack number, aura) was also tested.As study participants, 161 female migraine patients (63 with aura; 52 with WMLs) and 40 age-matched healthy female subjects were enrolled in the study. None of the included migraine patients' headache or aura (where present) was unilaterally side-locked. Patients and controls were all right handed. Except for migraine, patients were free of any medical comorbidity. Cortical reconstruction and segmentation were performed on the 3D T1-weighted images using Freesurfer 5.3 image analysis suite. The automatic cortical parcellation was based on Freesurfer's Desikan-Killiany-Tourville atlas, which has 31 cortical regions per hemisphere. The segmented regions were divided into five lobes (frontal, parietal, temporal, occipital, insula). Since the left and right differences in lobar and insular volumes/thicknesses were not different among our groups, volume and cortical thickness were calculated for corresponding bilateral lobes.There was no significant difference in age between the whole migraine and the control groups. Migraineurs with WMLs (L+ patients) were significantly older than lesion-free (L-) patients (P = 0.0003) and controls (P = 0.018). Disease duration (P = 0.003), the total number of migraine attacks (P = 0.022) and the rate of aura (P = 0.0003) were significantly higher in L+ patients than in L- patients. Cortical thickness and volume measurements of lobes were not statistically different between the three groups (L+, L-, control). Age showed a significant negative association with both thickness and volume in each examined lobe (P < 0.001). Intracranial volume (ICV) showed a significant positive association with all regional volumes (P < 0.001). There were no significant group*age, group*ICV, or age*ICV interactions. None of the migraine characteristics were selected by stepwise linear regression as significant predictors of cortical thickness or volume. Only age (for both thickness and volume) and ICV (for volume) were identified as significant predictors (P < 0.001). When the L + group was divided into two subgroups by median split of total and lobar lesion number and volume, the cortical measures did not show any significant difference between the groups with low vs. high lesion number/volume by stepwise linear regression.In a female migraine group, we found that the WMLs and clinical migraine characteristics have no effect on cortical thickness and volume of bilateral lobes. Lobar cortical thicknesses were equivalent within the range of ±0.1 mm. Only age and ICV proved to be significant predictors; the former for both cortical thickness and volume, while the latter for cortical volume.},
	keywords = {AGE; Magnetic Resonance Imaging; Cortical reconstruction and segmentation; Intracranial volume; Lobar cortical thickness and volume; Migraine headache characteristics; Migraine-related intracerebral white matter lesions},
	year = {2019},
	eissn = {1129-2377},
	orcid-numbers = {Nagy, Szilvia Anett/0000-0001-6483-9209}
}

@article{MTMT:30651227,
	title = {Cerebrovascular reactivity as a determinant of deep white matter hyperintensities in migraine},
	url = {https://m2.mtmt.hu/api/publication/30651227},
	author = {Lee, Mi Ji and Park, Bo-Yong and Cho, Soohyun and Park, Hyunjin and Chung, Chin-Sang},
	doi = {10.1212/WNL.0000000000006822},
	journal-iso = {NEUROLOGY},
	journal = {NEUROLOGY},
	volume = {92},
	unique-id = {30651227},
	issn = {0028-3878},
	abstract = {Objective To evaluate the association between the cerebrovascular reactivity to carbon dioxide (CO2-CVR) and the deep white matter hyperintensity (WMH) burden in patients with migraine. Methods A total of 86 nonelderly patients with episodic migraine without vascular risk factors and 35 headache-free controls underwent 3T MRI. Deep WMHs were quantified with a segmentation method developed for nonelderly migraineurs. The interictal CO2-CVR was measured with transcranial Doppler with the breath-holding method. The mean breath-holding index of the bilateral middle cerebral arteries (MCA-BHI) was square root transformed and analyzed with univariate and multivariate logistic regression models to determine its association with the highest tertiles of deep WMH burden (number and volume). Results A low MCA-BHI was independently associated with the highest tertile of deep WMH number in patients with migraine (adjusted odds ratio [OR] 0.02, 95% confidence interval [CI] 0.0007-0.63, p = 0.026). In controls, the MCA-BHI was not associated with deep WMH number. Interaction analysis revealed that migraine modified the effect of MCA-BHI on deep WMH number (p for interaction = 0.029). The MCA-BHI was not associated with increased deep WMH volume in both patients and controls. Age was independently associated with deep WMH volume in patients (adjusted OR 1.07, 95% CI 1.004-1.15, p = 0.037). Conclusions In this study, we found a migraine-specific association between a reduced CVR to apnea and increased number of deep WMHs in healthy, nonelderly patients with migraine. A dysfunctional vascular response to apnea may predispose migraineurs to an increased risk of WMHs.},
	year = {2019},
	eissn = {1526-632X},
	pages = {E342-E350},
	orcid-numbers = {Lee, Mi Ji/0000-0003-1364-1969}
}

@article{MTMT:30610534,
	title = {Correlations Between Endothelial Dysfunction and Cerebral Imaging in Migraine},
	url = {https://m2.mtmt.hu/api/publication/30610534},
	author = {Sacmaci, Hikmet and Mirza, Meral and Bisiren, Sukru and Gokahmetoglu, Selma and Saraymen, Recep and Talaslioglu, Abdullah},
	doi = {10.4274/tnd.galenos.2018.81904},
	journal-iso = {TURK NOROLOJI DERGISI},
	journal = {TURK NOROLOJI DERGISI},
	volume = {25},
	unique-id = {30610534},
	issn = {1301-062X},
	abstract = {Objective Despite its high prevalence, the basic pathophysiologic mechanism of migraine is still poorly understood. Our aim was to research endothelial dysfunction in patients with recently diagnosed episodic migraine, and to determine whether there was a correlation between endothelial dysfunction and white matter lesions (WMLs) on magnetic resonance imaging (MRI).},
	keywords = {MIGRAINE; ENDOTHELIN; White matter lesions; Flow-mediated dilatation},
	year = {2019},
	pages = {12-18}
}

@article{MTMT:30822529,
	title = {Prevalence of White Matter Hyperintensity in Young Clinical Patients},
	url = {https://m2.mtmt.hu/api/publication/30822529},
	author = {Wang, Ming-Liang and Zhang, Xiao-Xing and Yu, Meng-Meng and Li, Wen-Bin and Li, Yue-Hua},
	doi = {10.2214/AJR.18.20888},
	journal-iso = {AM J ROENTGENOL},
	journal = {AMERICAN JOURNAL OF ROENTGENOLOGY},
	volume = {213},
	unique-id = {30822529},
	issn = {0361-803X},
	abstract = {OBJECTIVE. The purpose of this study was to investigate the prevalence of white matter hyperintensity (WMH) without specific causes in young clinical outpatients.MATERIALS AND METHODS. A total of 1249 young clinical outpatients who underwent an unenhanced head MRI examination between January 1, 2016, and December 31, 2016, were included in the study. The chi-square test was used to analyze differences in the prevalence and characteristics of WMH by sex, age, and history of cardiovascular disease (CVD). The prevalence of WMH among clinical patients with neurologic symptoms was also compared with that among participants without neurologic symptoms. Logistic regression was used to identify the patient characteristics that were the best predictors of WMH.RESULTS. The overall prevalence of WMH was 25.94% (324/1249). Most patients with WMH (85.49% [277/324]) had mild WMH, mainly in frontal and parietal subcortical white matter. There was no significant difference in the prevalence of WMH by sex (p > 0.05), but the prevalence of WMH was higher among older patients (p < 0.001) and patients with a history of CVD (p < 0.001). Compared with participants without neurologic symptoms, clinical patients with dizziness (p = 0.029) and light-headedness (p = 0.001) were more likely to have WMH, which was attributed to older age and CVD. Logistic regression analysis showed that age and CVD were the best predictors of WMH.CONCLUSION. WMH is frequently found in young clinical patients. Most WMH is the mild type and mainly located in frontal and parietal subcortical white matter. Older age and CVD are risk factors for WMH.},
	keywords = {PREVALENCE; MRI; white matter hyperintensity; Young patients},
	year = {2019},
	eissn = {1546-3141},
	pages = {667-671}
}

@article{MTMT:31296568,
	title = {Magnetic Resonance Imaging in Pediatric Migraine},
	url = {https://m2.mtmt.hu/api/publication/31296568},
	author = {Webb, M.E. and Amoozegar, F. and Harris, A.D.},
	doi = {10.1017/cjn.2019.243},
	journal-iso = {CAN J NEUROL SCI},
	journal = {CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES},
	volume = {46},
	unique-id = {31296568},
	issn = {0317-1671},
	year = {2019},
	eissn = {2057-0155},
	pages = {653-665}
}

@article{MTMT:26834630,
	title = {Metabolic assessment of a migraine model using relaxation-enhanced 1H spectroscopy at ultrahigh field},
	url = {https://m2.mtmt.hu/api/publication/26834630},
	author = {Abad, Nastaren and Rosenberg, Jens T and Roussel, Tangi and Grice, Dillon C and Harrington, Michael G and Grant, Samuel C},
	doi = {10.1002/mrm.26811},
	journal-iso = {MAGN RESON MED},
	journal = {MAGNETIC RESONANCE IN MEDICINE},
	volume = {79},
	unique-id = {26834630},
	issn = {0740-3194},
	abstract = {PurposeThis study evaluates biochemical imbalances in a rat model that reflects dysfunctional pathways in migraine. The high sensitivity and spectral dispersion available to H-1 MRS at 21.1T expands metabolic profiling in this migraine model to include lactate (Lac), taurine (Tau), aspartate, and Glya mixture of glycine, glutamine, and glutamate. MethodsSprague-Dawley male rats were administered in situ an intraperitoneal injection of nitroglycerin (NTG) to induce the migraine analogue or saline as a control. A selective relaxation-enhanced MR spectroscopy sequence was used to target upfield metabolites from a 4-mm(3) voxel for 2.5h after injection. ResultsSignificant increases were evident for Lac as early as 10min after NTG injection, peaking over 50% compared with baseline and control (normalized Lac/N-acetyl aspartate with NTG=1.540.65 versus with saline=0.99 +/- 0.08). Tau decreased progressively in controls over 2h after injection, but remained elevated with NTG, peaking at 105min after injection (normalized Tau/N-acetyl aspartate with NTG=1.10 +/- 0.18 versus with saline=0.85 +/- 0.14). Total creatine under NTG showed significant decreases with time and compared with saline; Gly demonstrated temporal increases for NTG. ConclusionsThese changes indicate an altered metabolic profile in the migraine analogue consistent with early changes in neural activity and/or vasodilation consistent with progressively enhanced neuroprotection and osmoregulation. Magn Reson Med 79:1266-1275, 2018. (c) 2017 International Society for Magnetic Resonance in Medicine.},
	keywords = {Brain; IN-VIVO; CEREBROSPINAL-FLUID; TAURINE; NITROGLYCERIN; MIGRAINE; LACTATE; MAGNETIC-RESONANCE-SPECTROSCOPY; ENERGY-METABOLISM; Proton MR spectroscopy; high magnetic field; hemiplegic migraine; H-1 MR spectroscopy; SODIUM INCREASES},
	year = {2018},
	eissn = {1522-2594},
	pages = {1266-1275}
}

@article{MTMT:30703185,
	title = {Changes of primary headache related white matter lesions in pediatric patients},
	url = {https://m2.mtmt.hu/api/publication/30703185},
	author = {Bayram, Erhan and Yis, Uluc and Paketci, Gem and Okur, Derya and Polat, Ipek and Cakmakci, Handan and Hiz, Semra and Anlar, Banu},
	doi = {10.24953/turkjped.2018.04.004},
	journal-iso = {TURKISH J PEDIATR},
	journal = {TURKISH JOURNAL OF PEDIATRICS},
	volume = {60},
	unique-id = {30703185},
	issn = {0041-4301},
	abstract = {We aimed to describe the long-term prognosis of white matter lesions detected on magnetic resonance imaging in children with primary headache. Children who were admitted with the complaint of headache and had nonspecific white matter lesions on magnetic resonance imaging were included in the study. The clinical findings of the patients were reinvestigated using the same magnetic resonance imaging scanner and acquisition protocol after at least a two year period. Magnetic resonance imaging results of the patients were documented in detail. Findings of the baseline and follow-up studies were compared with each other by the same radiologist. Among the 11 patients, 8 (72.7%) were male and 3 (27.3%) were female. Mean age of patients at the time of second imaging was 12.9 +/- 2.3 years. Eight (72.7%) had migraine without aura, 1 (9.1%) had tension-type headache and 2 (18.2%) had migraine with aura. The mean clinical follow-up period of the patients was 4.31 +/- 1.31 years. All patients had low headache frequency on the last control visit when compared to the first clinical findings. The follow-up magnetic resonance imaging studies showed two newly developed white matter lesions in two patients who had migraine without aura and the white matter lesions disappeared in the patient who had tension-type headache, compared to the baseline neuroimaging. Findings of the baseline and long-term follow-up magnetic resonance imaging studies of the patients with primary headache showed no significant changes in terms of the location, size and laterality. Repeated neuro-imaging studies are not warranted in the absence of the progression in clinical findings.},
	keywords = {CHILDREN; Magnetic Resonance Imaging; headache; White matter lesions; longterm evaluation},
	year = {2018},
	eissn = {0041-4301},
	pages = {380-384}
}

@article{MTMT:27033867,
	title = {The role of migraine headache severity, associated features and interactions with overweight/obesity in inhibitory control},
	url = {https://m2.mtmt.hu/api/publication/27033867},
	author = {Galioto, Rachel and O'Leary, Kevin C and Gunstad, John and Thomas, J Graham and Lipton, Richard B and Pavlovic, Jelena M and Roth, Julie and Rathier, Lucille and Bond, Dale S},
	doi = {10.1080/00207454.2017.1366474},
	journal-iso = {INT J NEUROSCI},
	journal = {INTERNATIONAL JOURNAL OF NEUROSCIENCE},
	volume = {128},
	unique-id = {27033867},
	issn = {0020-7454},
	abstract = {Aim of the Study: While migraine and obesity are related and both conditions are associated with reduced executive functioning, no study has examined whether obesity exacerbates executive dysfunction in migraine. This cross-sectional study examined whether overweight/obesity moderated associations of migraine severity and associated features with inhibitory control, one aspect of executive function.Materials and Methods: Women (n = 124) aged 18-50years old with overweight/obesity body mass index (BMI) = 35.1 6.4 kg/m(2) and migraine completed a 28-day smartphone-based headache diary assessing migraine headache severity (attack frequency, pain intensity) and frequency of associated features (aura, photophobia, phonophobia, nausea). They then completed computerized measures of inhibitory control during an interictal (headache-free) period.Results: Participants with higher migraine attack frequency performed worse on the Flanker test (accuracy and reaction time; p < .05). Migraine attack frequency and pain intensity interacted with BMI to predict slower Stroop and/or Flanker Reaction Time (RT; p < .05). More frequent photophobia, phonophobia and aura were independently related to slower RT on the Stroop and/or Flanker tests (p < .05), and BMI moderated the relationship between the occurrence of aura and Stroop RT (p = .03).Conclusions: Associations of migraine severity and presence of associated features with inhibitory control varied by BMI in overweight/obese women with migraine. These findings warrant consideration of weight status in clarifying the role of migraine in executive functioning.},
	keywords = {MIGRAINE; CEREBRAL-BLOOD-FLOW; OBESITY; OBESITY; headache; executive functions; WHITE-MATTER LESIONS; Cognitive function; OLDER-ADULTS; RESTING-STATE NETWORK; EXECUTIVE DYSFUNCTION; POSSIBLE MECHANISMS; HEALTHY-ADULTS},
	year = {2018},
	eissn = {1563-5279},
	pages = {63-70}
}

@article{MTMT:30329009,
	title = {Cognitive impairment in patients with migraine: Causes, principles of effective prevention and treatment},
	url = {https://m2.mtmt.hu/api/publication/30329009},
	author = {Golovacheva, V.A. and Pozhidaev, K.A. and Golovacheva, A.A.},
	doi = {10.14412/2074-2711-2018-3-141-149},
	journal-iso = {NEVROLOGIYA NEIROPSIKHIATRIYA PSIKHOSOMATIKA},
	journal = {NEVROLOGIYA NEIROPSIKHIATRIYA PSIKHOSOMATIKA},
	volume = {10},
	unique-id = {30329009},
	issn = {2074-2711},
	year = {2018},
	eissn = {2310-1342},
	pages = {141-149}
}

@article{MTMT:30376697,
	title = {White matter hyperintensities and headache: A population-based imaging study (HUNT MRI)},
	url = {https://m2.mtmt.hu/api/publication/30376697},
	author = {Honningsvag, Lasse-Marius and Haberg, Asta Kristine and Hagen, Knut and Kvistad, Kjell Arne and Stovner, Lars Jacob and Linde, Mattias},
	doi = {10.1177/0333102418764891},
	journal-iso = {CEPHALALGIA},
	journal = {CEPHALALGIA},
	volume = {38},
	unique-id = {30376697},
	issn = {0333-1024},
	abstract = {Objective To examine the relationship between white matter hyperintensities and headache. Methods White matter hyperintensities burden was assessed semi-quantitatively using Fazekas and Scheltens scales, and by manual and automated volumetry of MRI in a sub-study of the general population-based Nord-Trondelag Health Study (HUNT MRI). Using validated questionnaires, participants were categorized into four cross-sectional headache groups: Headache-free (n = 551), tension-type headache (n = 94), migraine (n = 91), and unclassified headache (n = 126). Prospective questionnaire data was used to further categorize participants into groups according to the evolution of headache during the last 12 years: Stable headache-free, past headache, new onset headache, and persistent headache. White matter hyperintensities burden was compared across headache groups using adjusted multivariate regression models. Results Individuals with tension-type headache were more likely to have extensive white matter hyperintensities than headache-free subjects, with this being the case across all methods of white matter hyperintensities assessment (Scheltens scale: Odds ratio, 2.46; 95% CI, 1.44-4.20). Migraine or unclassified headache did not influence the odds of having extensive white matter hyperintensities. Those with new onset headache were more likely to have extensive white matter hyperintensities than those who were stable headache-free (Scheltens scale: Odds ratio, 2.24; 95% CI, 1.13-4.44). Conclusions Having tension-type headache or developing headache in middle age was linked to extensive white matter hyperintensities. These results were similar across all methods of assessing white matter hyperintensities. If white matter hyperintensities treatment strategies emerge in the future, this association should be taken into consideration.},
	keywords = {RISK-FACTOR; PREVALENCE; BLOOD-PRESSURE; LESIONS; MIGRAINE; questionnaire; ABNORMALITIES; White matter lesions; Leukoaraiosis; white matter disease; NORD-TRONDELAG HEALTH; Clinical Neurology; SMALL VESSEL DISEASE; SMALL VESSEL DISEASE; FLAIR; 1.5 tesla},
	year = {2018},
	eissn = {1468-2982},
	pages = {1927-1939}
}

@article{MTMT:27536815,
	title = {DEWS (DEep White matter hyperintensity Segmentation framework): A fully automated pipeline for detecting small deep white matter hyperintensities in migraineurs},
	url = {https://m2.mtmt.hu/api/publication/27536815},
	author = {Park, Bo-yong and Lee, Mi Ji and Lee, Seung-hak and Cha, Jihoon and Chung, Chin-Sang and Kim, Sung Tae and Park, Hyunjin},
	doi = {10.1016/j.nicl.2018.02.033},
	journal-iso = {NEUROIMAGE-CLIN},
	journal = {NEUROIMAGE-CLINICAL},
	publisher = {Elsevier B.V.},
	volume = {18},
	unique-id = {27536815},
	issn = {2213-1582},
	abstract = {Migraineurs show an increased load of white matter hyperintensities (WMHs) and more rapid deep WMH progression. Previous methods for WMH segmentation have limited efficacy to detect small deep WMHs. We developed a new fully automated detection pipeline, DEWS (DEep White matter hyperintensity Segmentation framework), for small and superficially-located deep WMHs. A total of 148 non-elderly subjects with migraine were included in this study. The pipeline consists of three components: 1) white matter (WM) extraction, 2) WMH detection, and 3) false positive reduction. In WM extraction, we adjusted the WM mask to re-assign misclassified WMHs back to WM using many sequential low-level image processing steps. In WMH detection, the potential WMH clusters were detected using an intensity based threshold and region growing approach. For false positive reduction, the detected WMH clusters were classified into final WMHs and non-WMHs using the random forest (RF) classifier. Size, texture, and multi-scale deep features were used to train the RF classifier. DEWS successfully detected small deep WMHs with a high positive predictive value (PPV) of 0.98 and true positive rate (TPR) of 0.70 in the training and test sets. Similar performance of PPV (0.96) and TPR (0.68) was attained in the validation set. DEWS showed a superior performance in comparison with other methods. Our proposed pipeline is freely available online to help the research community in quantifying deep WMHs in non-elderly adults.},
	keywords = {MIGRAINE; Automated detection; Deep white matter hyperintensity},
	year = {2018},
	eissn = {2213-1582},
	pages = {638-647},
	orcid-numbers = {Park, Hyunjin/0000-0001-5681-8918}
}

@article{MTMT:30329008,
	title = {Characteristics and clinical correlates of white matter changes in brain magnetic resonance of migraine females},
	url = {https://m2.mtmt.hu/api/publication/30329008},
	author = {Rościszewska-Żukowska, I. and Zając-Mnich, M. and Janik, P.},
	doi = {10.1016/j.pjnns.2018.09.007},
	journal-iso = {NEUROL NEUROCHIR POL},
	journal = {NEUROLOGIA I NEUROCHIRURGIA POLSKA},
	volume = {52},
	unique-id = {30329008},
	issn = {0028-3843},
	year = {2018},
	eissn = {1897-4260},
	pages = {695-703}
}

@article{MTMT:27469249,
	title = {An Investigation of the Prevalence of Subclinical Brain Lesions in MRI Images of Migraine Patients},
	url = {https://m2.mtmt.hu/api/publication/27469249},
	author = {Tehrani, Khadijeh Haji Naghi},
	doi = {10.3889/oamjms.2018.263},
	journal-iso = {OPEN ACCESS MACED J MED SCI},
	journal = {OPEN ACCESS MACEDONIAN JOURNAL OF MEDICAL SCIENCES},
	volume = {6},
	unique-id = {27469249},
	year = {2018},
	eissn = {1857-9655},
	pages = {1239-1243}
}

@article{MTMT:30570740,
	title = {Episodic Migraine and White Matter Hyperintensities: Association of Pain Lateralization},
	url = {https://m2.mtmt.hu/api/publication/30570740},
	author = {Yalcin, Ahmet and Ceylan, Mustafa and Bayraktutan, Omer Faruk and Akkurt, Adem},
	doi = {10.1093/pm/pnx312},
	journal-iso = {PAIN MED},
	journal = {PAIN MEDICINE},
	volume = {19},
	unique-id = {30570740},
	issn = {1526-2375},
	abstract = {Background. Migraine pathophysiology involves a neuronal mechanism that is closely associated with the neuronal activation of peripheral trigeminal nociceptive pathways. It also involves a vascular mechanism that is supported by studies concerning the presence of migraine with aura in various vascular diseases. Migraine is associated with silent infarctlike lesions and whitematter hyperintensities (WMHs) that can be encountered during magnetic resonance imaging. In this study, we aimed to demonstrate the migraine-WMH link based on pain lateralization.},
	keywords = {MIGRAINE; white matter hyperintensity; Pain Lateralization},
	year = {2018},
	eissn = {1526-4637},
	pages = {2051-2057}
}

@article{MTMT:26991357,
	title = {Cardiovascular risk factors and white matter hyperintensities in patients with migraine without aura},
	url = {https://m2.mtmt.hu/api/publication/26991357},
	author = {Ceyla, Ataç UÇAR and Hafize, Nalan GÜNEŞ and Cemile, SENCER DEMİRCAN and Burcu, Gökçe ÇOKAL and Selda, KESKİN GÜLER and Tahir, Kurtuluş YOLDAŞ},
	doi = {10.5505/agri.2017.43765},
	journal-iso = {AGRI},
	journal = {AGRI: TURK ALGOLOJI DERNEGI'NIN YAYIN ORGANIDIR},
	volume = {29},
	unique-id = {26991357},
	issn = {1300-0012},
	year = {2017},
	eissn = {2458-9446},
	pages = {157-161}
}

@article{MTMT:26505394,
	title = {Migraine white matter hyperintensities and cerebral microinfarcts are silent cryptogenic strokes and relate to dementia},
	url = {https://m2.mtmt.hu/api/publication/26505394},
	author = {Eggers, AE},
	doi = {10.1016/j.mehy.2017.03.004},
	journal-iso = {MED HYPOTHESES},
	journal = {MEDICAL HYPOTHESES},
	volume = {102},
	unique-id = {26505394},
	issn = {0306-9877},
	year = {2017},
	eissn = {1532-2777},
	pages = {1-3}
}

@article{MTMT:3055175,
	title = {Serum L-arginine and Dimethylarginine Levels in Migraine Patients with Brain White Matter Lesions},
	url = {https://m2.mtmt.hu/api/publication/3055175},
	author = {Erdélyi-Bótor, Szilvia and Komáromy, Hedvig and Kamson Olayinka, Dávid and Kovács, Norbert and Perlaki, Gábor and Orsi, Gergely and Molnár, Tihamér and Illés, Zsolt László and Nagy, Lajos and Kéki, Sándor and Deli, Gabriella and Bosnyák, Edit and Trauninger, Anita and Pfund, Zoltán},
	doi = {10.1177/0333102416651454},
	journal-iso = {CEPHALALGIA},
	journal = {CEPHALALGIA},
	volume = {37},
	unique-id = {3055175},
	issn = {0333-1024},
	keywords = {RISK; NITRIC-OXIDE; INJURY; MIGRAINE; CEREBRAL-BLOOD-FLOW; CARDIOVASCULAR-DISEASE; COMMUNITY; MRI; L-arginine; ASYMMETRIC DIMETHYLARGININE; ADMA; HYPERINTENSITIES; VASCULAR ENDOTHELIAL DYSFUNCTION; SDMA; white matter lesion; Oxidative stress},
	year = {2017},
	eissn = {1468-2982},
	pages = {571-580},
	orcid-numbers = {Kovács, Norbert/0000-0002-7332-9240; Illés, Zsolt László/0000-0001-9655-0450}
}

@article{MTMT:26584310,
	title = {Lower inhibitory control interacts with greater pain catastrophizing to predict greater pain intensity in women with migraine and overweight/obesity},
	url = {https://m2.mtmt.hu/api/publication/26584310},
	author = {Galioto, Rachel and O'Leary, Kevin C and Thomas, J Graham and Demos, Kathryn and Lipton, Richard B and Gunstad, John and Pavlovic, Jelena M and Roth, Julie and Rathier, Lucille and Bond, Dale S},
	doi = {10.1186/s10194-017-0748-8},
	journal-iso = {J HEADACHE PAIN},
	journal = {JOURNAL OF HEADACHE AND PAIN},
	volume = {18},
	unique-id = {26584310},
	issn = {1129-2369},
	year = {2017},
	eissn = {1129-2377}
}

@{MTMT:27045740,
	title = {Neuroimaging in migraines},
	url = {https://m2.mtmt.hu/api/publication/27045740},
	author = {Russo, A and Tessitore, A and Tedeschi, G},
	booktitle = {Neuroimaging of Pain},
	doi = {10.1007/978-3-319-48046-6_10},
	publisher = {Springer Netherlands},
	unique-id = {27045740},
	year = {2017},
	pages = {267-295}
}

@article{MTMT:26669808,
	title = {Disease progression and regression in sporadic small vessel disease-insights from neuroimaging},
	url = {https://m2.mtmt.hu/api/publication/26669808},
	author = {van Leijsen, Esther M C and de Leeuw, Frank-Erik and Tuladhar, Anil M},
	doi = {10.1042/CS20160384},
	journal-iso = {CLIN SCI},
	journal = {CLINICAL SCIENCE},
	volume = {131},
	unique-id = {26669808},
	issn = {0143-5221},
	year = {2017},
	eissn = {1470-8736},
	pages = {1191-1206}
}

@article{MTMT:25554276,
	title = {Morphogenesis of the demyelinating lesions in Baló’s concentric sclerosis},
	url = {https://m2.mtmt.hu/api/publication/25554276},
	author = {Barz, Helmut and Barz, Ulrich and Schreiber, Almut},
	doi = {10.1016/j.mehy.2016.03.016},
	journal-iso = {MED HYPOTHESES},
	journal = {MEDICAL HYPOTHESES},
	volume = {91},
	unique-id = {25554276},
	issn = {0306-9877},
	year = {2016},
	eissn = {1532-2777},
	pages = {56-61}
}

@article{MTMT:26251290,
	title = {Migraine: What Imaging Reveals},
	url = {https://m2.mtmt.hu/api/publication/26251290},
	author = {Chong, Catherine D and Schwedt, Todd J and Dodick, David W},
	doi = {10.1007/s11910-016-0662-5},
	journal-iso = {CURR NEUROL NEUROSCI},
	journal = {CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS},
	volume = {16},
	unique-id = {26251290},
	issn = {1528-4042},
	year = {2016},
	eissn = {1534-6293}
}

@article{MTMT:32709561,
	title = {Structural Changes in the Cerebrum, Cerebellum and Corpus Callosum in Migraine Patients},
	url = {https://m2.mtmt.hu/api/publication/32709561},
	author = {Demir, B.T. and Bayram, N.A. and Ayturk, Z. and Erdamar, H. and Seven, P. and Calp, A. and Sazak, M. and Ceylan, H.G.},
	doi = {10.25011/CIM.V39I6.27495},
	journal-iso = {CLIN INVEST MED},
	journal = {CLINICAL AND INVESTIGATIVE MEDICINE},
	volume = {39},
	unique-id = {32709561},
	issn = {0147-958X},
	year = {2016},
	eissn = {1488-2353},
	pages = {21-26}
}

@article{MTMT:32789055,
	title = {The migraine-stroke connection},
	url = {https://m2.mtmt.hu/api/publication/32789055},
	author = {Lee, M.J. and Lee, C. and Chung, C.-S.},
	doi = {10.5853/jos.2015.01683},
	journal-iso = {J STROKE},
	journal = {JOURNAL OF STROKE},
	volume = {18},
	unique-id = {32789055},
	issn = {2287-6391},
	year = {2016},
	eissn = {2287-6405},
	pages = {146-156}
}

@article{MTMT:25880089,
	title = {Incidental Lesions Suggesting Multiple Sclerosis},
	url = {https://m2.mtmt.hu/api/publication/25880089},
	author = {Okuda, Darin T},
	doi = {10.1212/CON.0000000000000339},
	journal-iso = {CONTINUUM (BALTIMORE)},
	journal = {CONTINUUM: LIFELONG LEARNING IN NEUROLOGY (BALTIMORE)},
	volume = {22},
	unique-id = {25880089},
	issn = {1080-2371},
	year = {2016},
	eissn = {1538-6899},
	pages = {730-743}
}

@article{MTMT:26251289,
	title = {New daily persistent headache: A lack of an association with white matter abnormalities on neuroimaging},
	url = {https://m2.mtmt.hu/api/publication/26251289},
	author = {Rozen, Todd D},
	doi = {10.1177/0333102415612766},
	journal-iso = {CEPHALALGIA},
	journal = {CEPHALALGIA},
	volume = {36},
	unique-id = {26251289},
	issn = {0333-1024},
	year = {2016},
	eissn = {1468-2982},
	pages = {987-992}
}

@article{MTMT:25261363,
	title = {Longitudinal change of small-vessel disease-related brain abnormalities},
	url = {https://m2.mtmt.hu/api/publication/25261363},
	author = {Schmidt, R and Seiler, S and Loitfelder, M},
	doi = {10.1038/jcbfm.2015.72},
	journal-iso = {J CEREBR BLOOD F MET},
	journal = {JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM},
	volume = {36},
	unique-id = {25261363},
	issn = {0271-678X},
	year = {2016},
	eissn = {1559-7016},
	pages = {26-39}
}

@article{MTMT:26328126,
	title = {Characteristics of cerebral white matter lesions on MRI in juvenile patients with migraine},
	url = {https://m2.mtmt.hu/api/publication/26328126},
	author = {Yasuda, T and Kodera, Y and Iijima, K and Mizuma, A and Tokuoka, K and Okuma, H and Takizawa, S and Kitagawa, Y and Nogawa, S},
	journal-iso = {TOKAI J EXP CLIN MED},
	journal = {TOKAI JOURNAL OF EXPERIMENTAL AND CLINICAL MEDICINE},
	volume = {41},
	unique-id = {26328126},
	issn = {0385-0005},
	year = {2016},
	eissn = {2185-2243},
	pages = {156-162}
}

@article{MTMT:25185017,
	title = {Statins for all: Should patients who have migraine with aura be on a statin?},
	url = {https://m2.mtmt.hu/api/publication/25185017},
	author = {Kernick, D},
	doi = {10.3399/bjgp15X687253},
	journal-iso = {BRIT J GEN PRACT},
	journal = {BRITISH JOURNAL OF GENERAL PRACTICE},
	volume = {65},
	unique-id = {25185017},
	issn = {0960-1643},
	year = {2015},
	eissn = {1478-5242},
	pages = {571-572}
}

@article{MTMT:25185011,
	title = {New players in the preventive treatment of migraine},
	url = {https://m2.mtmt.hu/api/publication/25185011},
	author = {Mitsikostas, DD and Rapoport, AM},
	doi = {10.1186/s12916-015-0522-1},
	journal-iso = {BMC MED},
	journal = {BMC MEDICINE},
	volume = {13},
	unique-id = {25185011},
	issn = {1741-7015},
	year = {2015},
	eissn = {1741-7015}
}

@article{MTMT:25362050,
	title = {Magnetic resonance brain imaging in patients with visual vertigo},
	url = {https://m2.mtmt.hu/api/publication/25362050},
	author = {Pollak, L and Osherov, M and Berkovitz, N and Beckerman, I and Stryjer, R and Tal, S},
	doi = {10.1002/brb3.402},
	journal-iso = {BRAIN BEHAV},
	journal = {BRAIN AND BEHAVIOR},
	volume = {5},
	unique-id = {25362050},
	issn = {2162-3279},
	year = {2015},
	eissn = {2162-3279}
}

@article{MTMT:25266518,
	title = {Central integration of canal and otolith signals is abnormal in vestibular migraine: a commentary},
	url = {https://m2.mtmt.hu/api/publication/25266518},
	author = {Valenca, Marcelo M},
	doi = {10.3389/fneur.2014.00263},
	journal-iso = {FRONT NEUR},
	journal = {FRONTIERS IN NEUROLOGY},
	volume = {5},
	unique-id = {25266518},
	issn = {1664-2295},
	year = {2015},
	eissn = {1664-2295}
}