TY - THES AU - Hajas, Orsolya TI - Changes in intracardiac haemostasis parameters during catheter ablation of atrial fibrillation in relation to the ablation technology and the periprocedural anticoagulation PY - 2021 UR - https://m2.mtmt.hu/api/publication/34645264 ID - 34645264 LA - English DB - MTMT ER - TY - JOUR AU - Lasek-Bal, Anetta AU - Puz, Przemyslaw AU - Wieczorek, Joanna AU - Nowak, Seweryn AU - Wnuk-Wojnar, Anna Maria AU - Warsz-Wianecka, Aldona AU - Mizia-Stec, Katarzyna TI - Cerebral microembolism during atrial fibrillation ablation can result from the technical aspects and mostly does not cause permanent neurological deficit JF - ARCHIVES OF MEDICAL SCIENCE J2 - ARCH MED SCI VL - 16 PY - 2020 IS - 6 SP - 1288 EP - 1294 PG - 7 SN - 1734-1922 DO - 10.5114/aoms.2020.94747 UR - https://m2.mtmt.hu/api/publication/31728594 ID - 31728594 N1 - Department of Neurology, School of Health Sciences, Medical University of Silesia, Katowice, Poland First Department of Cardiology, School of Medicine, Medical University of Silesia, Katowice, Poland Export Date: 14 August 2023 Correspondence Address: Lasek-Bal, A.; Department of Neurology, 45/47 Ziołowa St, Poland; email: abal@sum.edu.pl Chemicals/CAS: heparin, 37187-54-5, 8057-48-5, 8065-01-8, 9005-48-5 Tradenames: Achieve, Medtronic, United States; Arctic Front Advance, Medtronic, United States; CARTO 3, Biosense Webster, United States; Lasso (device), Biosense Webster, United States; ThermoCool SmartTouch, Biosense Webster, United States Manufacturers: Biosense Webster, United States; Medtronic, United States AB - Introduction: Atrial fibrillation ablation can be associated with microembolism detected in the intracranial arteries and risk of neurological incidents. The aims of this study were to evaluate microembolic signals (MES) during pulmonary vein isolation (PVI) and establish the potential significance of MES for damage of the brain in radiological investigation and neurological state.Material and methods: In the prospective study we included patients with atrial fibrillation undergoing percutaneous pulmonary vein isolation (radiofrequency ablation/balloon cryoablation) with ultrasound monitoring of microembolisms in the middle cerebral artery. Neurological examination and MRI of the head were performed in all participants.Results: The study enrolled 80 patients at a mean age of 58 years. Microembolisms during the monitoring of the flow in the right middle cerebral artery were recorded in 61 (76.3%) patients in the amount of 51-489 (mean: 239). Most often the microembolic signals were registered during the trans-septal puncture and the stage of ablation. In 89%, microembolisms were gaseous. Mean score on the Fazekas scale for the whole group before ablation: 0.87 0.7 (0-3, med. 1); after: 0.93 0.71. In 3 (4.3%) patients the lesions worsened during the follow-up period. None of the patients revealed a cardiovascular event during the follow-up period and no changes were observed in the neurological status.Conclusions: The majority of cerebral microembolisms generated during PVI are gaseous in nature. The cerebral microembolisms associated with PVI probably result from the technical aspects of the procedure and do not cause either permanent brain damage in the radiological investigation or neurological deficit. LA - English DB - MTMT ER - TY - JOUR AU - Keçe, Fehmi AU - Bruggemans, Eline F. AU - de Riva, Marta AU - Alizadeh Dehnavi, Reza AU - Wijnmaalen, Adrianus P. AU - Meulman, Tamara J. AU - Brugman, Julia A. AU - Rooijmans, Anouk M. AU - van Buchem, Mark A. AU - Middelkoop, Huub A. AU - Eikenboom, Jeroen AU - Schalij, Martin J. AU - Zeppenfeld, Katja AU - Trines, Serge A. TI - Incidence and Clinical Significance of Cerebral Embolism During Atrial Fibrillation Ablation With Duty-Cycled Phased-Radiofrequency Versus Cooled-Radiofrequency JF - JACC: CLINICAL ELECTROPHYSIOLOGY J2 - JACC CLIN ELECTROPHYSIOL VL - 5 PY - 2019 IS - 3 SP - 318 EP - 326 PG - 9 SN - 2405-500X DO - 10.1016/j.jacep.2018.11.008 UR - https://m2.mtmt.hu/api/publication/30644605 ID - 30644605 LA - English DB - MTMT ER - TY - JOUR AU - Xu, Yun AU - Wang, Bing AU - Jiang, Li-Jiao AU - Lu, Xiao-Ping AU - Zhao, Xiao-Ying AU - Wang, Fang TI - Roles of Microembolus and Plasma D-dimer in the Evaluation of Warfarin Anticoagulant Therapy Efficacies for Patients with Atrial Fibrillation JF - HEART SURGERY FORUM J2 - HEART SURG FORUM VL - 22 PY - 2019 IS - 1 SP - E15 EP - E18 PG - 4 SN - 1098-3511 DO - 10.1532/hsf.2197 UR - https://m2.mtmt.hu/api/publication/30563659 ID - 30563659 AB - Background: To investigate the roles of microemboli and plasma D-dimer in the evaluation of warfarin anticoagulant therapy efficacies for patients with atrial fibrillation (AF). LA - English DB - MTMT ER - TY - JOUR AU - von Bary, Christian AU - Deneke, Thomas AU - Arentz, Thomas AU - Schade, Anja AU - Lehrmann, Heiko AU - Schwab-Malek, Susanne AU - Fredersdorf, Sabine AU - Baldaranov, Dobri AU - Maier, Lars AU - Schlachetzki, Felix TI - Clinical Impact of the Microembolic Signal Burden During Catheter Ablation for Atrial Fibrillation Just a Lot of Noise? JF - JOURNAL OF ULTRASOUND IN MEDICINE J2 - J ULTRAS MED VL - 37 PY - 2018 IS - 5 SP - 1091 EP - 1101 PG - 11 SN - 0278-4297 DO - 10.1002/jum.14447 UR - https://m2.mtmt.hu/api/publication/27562297 ID - 27562297 LA - English DB - MTMT ER - TY - JOUR AU - Nagy-Baló, Edina AU - Martirosyan, Mihran AU - Sándorfi, Gábor AU - Hajas, Orsolya AU - Levente, Lánczi AU - Berényi, Ervin László AU - Lilla, Ladányi AU - Kiss, Alexandra AU - Édes, István AU - Csanádi, Zoltán TI - Cerebral micro-embolization during pulmonary vein isolation: relation to post-ablation silent cerebral ischemia JF - CARDIOLOGY JOURNAL J2 - CARDIOL J VL - 24 PY - 2017 IS - 3 SP - 234 EP - 241 PG - 8 SN - 1897-5593 DO - 10.5603/CJ.a2017.0030 UR - https://m2.mtmt.hu/api/publication/3227096 ID - 3227096 AB - Background: High incidences of silent cerebral ischemia (SCI) have been revealed by diffusion-weighted magnetic resonance imaging (DW MRI) after pulmonary vein isolation (PVI) for atrial fibrillation. A high number of mostly gaseous micro-embolic signals (MESs) was detected by transcranial Doppler (TCD) during PVI. In this investigation the possible relationship between MESs detected intraoperatively by TCD and new SCI on DW MRI post-ablation is reported. Methods: 27 consecutive atrial fibrillation patients (6 female, age median: 64 interquartile range: 13.23) undergoing PVI with the pulmonary vein ablation catheter, pre- and post-ablation DW MRI and intraoperative MES detection by TCD were included in the study. Procedures were performed on a therapeutic international normalized ratio (2–3) and with a target activated clotting time ≥ 350 s in all patients. DW MRI scans performed pre- and post-ablation revealed new SCI in 6 out of 27 (22%) patients. Results: The median (interquartile range) MES count recorded during the whole procedure was 1642 (912) in patients with and 1019 (529) in those without SCI (p = 0.129). The number of MESs recorded during pulmonary vein angiography was significantly higher in patients as compared to those without a new lesion on the post-ablation DW MRI: 257 (249) vs. 110 (71), respectively (p = 0.0009). On multivariate logistic regression, the total MES count was predictive of SCI in patients older than 68 years. Conclusions: Micro-embolus generation detected by TCD during pulmonary vein angiography significantly correlates with new SCI on DW MRI post-ablation. LA - English DB - MTMT ER - TY - JOUR AU - von Bary, Christian AU - Deneke, Thomas AU - Arentz, Thomas AU - Schade, Anja AU - Lehrmann, Heiko AU - Fredersdorf, Sabine AU - Baldaranov, Dobri AU - Maier, Lars AU - Schlachetzki, Felix TI - Online Measurement of Microembolic Signal Burden by Transcranial Doppler during Catheter Ablation for Atrial Fibrillation - Results of a Multicenter Trial JF - FRONTIERS IN NEUROLOGY J2 - FRONT NEUR VL - 8 PY - 2017 PG - 9 SN - 1664-2295 DO - 10.3389/fneur.2017.00131 UR - https://m2.mtmt.hu/api/publication/26562233 ID - 26562233 LA - English DB - MTMT ER - TY - THES AU - Csanádi, Zoltán TI - Szívelektrofiziológiai intervenciók magas prevalenciájú kardiális kórképekben PB - Debreceni Egyetem PY - 2016 UR - https://m2.mtmt.hu/api/publication/3255804 ID - 3255804 LA - Hungarian DB - MTMT ER -