@article{MTMT:23083893,
	title = {the behaviour and cholinesterase inhibitory activity of fenthion and its products by light and chlorination},
	url = {https://m2.mtmt.hu/api/publication/23083893},
	author = {Tahara, M and Kubota, R and Nakazawa, H and Tokunaga, H and Nishimura, T},
	doi = {10.2166/aqua.2008.031},
	journal-iso = {J WATER SUPPLY RES T},
	journal = {JOURNAL OF WATER SUPPLY RESEARCH AND TECHNOLOGY-AQUA},
	volume = {57},
	unique-id = {23083893},
	issn = {1606-9935},
	year = {2008},
	eissn = {1605-3974},
	pages = {143-151}
}

@article{MTMT:1240518,
	title = {Functional neurotoxic effects in rats acutely exposed to insecticide combinations},
	url = {https://m2.mtmt.hu/api/publication/1240518},
	author = {Lengyel, Z and Szabó, Andrea and Papp, András and Nagymajtényi, László},
	doi = {10.1016/j.pestbp.2006.06.005},
	journal-iso = {PESTIC BIOCHEM PHYS},
	journal = {PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY},
	volume = {87},
	unique-id = {1240518},
	issn = {0048-3575},
	abstract = {The aim of the present study was to analyse the alterations in the cortical and peripheral electrophysiological activity of rats acutely treated with combinations of insecticides. Young adult male Wistar rats were treated with 1/5 and 1/25 LD50 of the insecticides dimethoate, propoxur, cypermethrin and amitraz, given alone or in triple or quadruple combinations. After 24 h, spontaneous cortical activity, and stimulus-evoked cortical and peripheral responses, was recorded and analysed. All treatments changed the cortical activity spectrum. The effect of the 1/5 LD50 combinations indicated non-additive interactions. In the cortical-evoked responses, dimethoate and its combinations gave the strongest change in the latency, while amitraz and its combinations, in the response duration. In the tail nerve, relative refractory period was the most sensitive parameter. The frequency dependence of the cortical responses was the most strongly altered by propoxur, and the least, by amitraz. Our results indicate that simultaneous exposure by various pesticide agents, which happens possibly also in humans, deserves further investigation in, among others, neurotoxicological points of view. Š 2006 Elsevier Inc. All rights reserved.},
	keywords = {Neurotoxicity; Rattus norvegicus; Peripheral activity; Insecticides; Cortical activity; Combined exposure; rat},
	year = {2007},
	eissn = {1095-9939},
	pages = {94-102},
	orcid-numbers = {Papp, András/0000-0003-0485-0806; Nagymajtényi, László/0000-0002-7848-4573}
}

@article{MTMT:22657767,
	title = {Animal models of chronic pesticide neurotoxicity},
	url = {https://m2.mtmt.hu/api/publication/22657767},
	author = {Moser, VC},
	doi = {10.1177/0960327106072395},
	journal-iso = {HUM EXP TOXICOL},
	journal = {HUMAN & EXPERIMENTAL TOXICOLOGY},
	volume = {26},
	unique-id = {22657767},
	issn = {0960-3271},
	year = {2007},
	eissn = {1477-0903},
	pages = {321-331}
}

@article{MTMT:1240509,
	title = {Stimulus frequency dependence of the central and peripheral somatosensory evoked activity in rats treated with various pesticides},
	url = {https://m2.mtmt.hu/api/publication/1240509},
	author = {Szabó, Andrea and Papp, András and Nagymajtényi, László},
	doi = {10.1556/ABiol.56.2005.3-4.4},
	journal-iso = {ACTA BIOL HUNG},
	journal = {ACTA BIOLOGICA HUNGARICA (1983-2018)},
	volume = {56},
	unique-id = {1240509},
	issn = {0236-5383},
	abstract = {Rats were treated with a combination of insecticide agents in different timing schemes. In acute administration, 1/5 LD50 of the three insecticides: dimethoate, propoxur and cypermethrin, or their combination, was given once by gavage. In the developmental model, female rats received oral doses of 1/25 LD50 of the above insecticides in combination in three timing schemes including pregnancy and lactation. Responses in the somatosensory cortex and in the tail nerve, evoked by peripheral electric stimulation, were recorded in acute preparation under urethane anesthesia. It was tested whether the parameters of the cortical and peripheral evoked response are dependent on the frequency and whether this dependence is different in control and treated animals. The latency increase of the cortical responses with increasing stimulation frequency was significantly stronger in rats treated acutely with cypermethrin and the combination, and in rats receiving the combination during both intra- and extrauterine development. On the duration, the effects were less clear. Frequency dependent increase of the tail nerve action potential latency was significantly intensified by cypermethrin, and the amplitude decrease, by cypermethrin and dimethoate. Fatigue of this response during a stimulation series was also altered by the insecticides. Frequency dependence and fatigue possibly reflect the actual state of the nervous system and may have the potency to be developed to functional biomarkers. Š 2005 AkadÊmiai Kiadó.},
	keywords = {Animals; Female; Humans; NEUROTOXIN; RATS; ARTICLE; human; animal; Electric Stimulation; TIME; physiology; Dose-Response Relationship, Drug; Time Factors; dose response; Animalia; drug effect; Pyrethrins; Peripheral Nerves; pyrethroid; pregnancy; propoxur; insecticide; dimethoate; cipermethrin; Neurotoxins; fatigue; evoked somatosensory response; electrostimulation; Somatosensory system; Neural Conduction; Evoked Potentials, Somatosensory; Action Potentials; action potential; peripheral nerve; Environmental Pollutants; Wistar rat; pollutant; Peripheral activity; Insecticides; Cortical activity; Rats, Wistar; nerve conduction; rat},
	year = {2005},
	eissn = {1588-256X},
	pages = {205-214},
	orcid-numbers = {Papp, András/0000-0003-0485-0806; Nagymajtényi, László/0000-0002-7848-4573}
}

@article{MTMT:1308195,
	title = {Comparative investigation of Behavioral, Neurotoxicological and Immuntoxicological Indices in Detection of Subacute Combined Exposure with methyl parathion and Propoxur in Rats},
	url = {https://m2.mtmt.hu/api/publication/1308195},
	author = {Institóris, László and Papp, András and Siroki, O and Banerjee, B D},
	doi = {10.1016/S0147-6513(03)00101-5},
	journal-iso = {ECOTOX ENVIRON SAFE},
	journal = {ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY},
	volume = {57},
	unique-id = {1308195},
	issn = {0147-6513},
	year = {2004},
	eissn = {1090-2414},
	pages = {270-277},
	orcid-numbers = {Papp, András/0000-0003-0485-0806}
}

@article{MTMT:23194988,
	title = {Methyl parathion in residential properties: Relocation and decontamination methodology},
	url = {https://m2.mtmt.hu/api/publication/23194988},
	author = {Clark, JM and Bing-Canar, J and Renninger, S and Dollpopf, R and El-Zein, J and Star, D and Zimmerman, D and Anisuzzaman, A and Boylan, K and Tomaszewski, T and Pearce, K and Yacovac, R and Erlwein, B and Ward, J},
	journal-iso = {ENVIRON HEALTH PERSP},
	journal = {ENVIRONMENTAL HEALTH PERSPECTIVES},
	volume = {110},
	unique-id = {23194988},
	issn = {0091-6765},
	year = {2002},
	eissn = {1552-9924},
	pages = {1061-1070}
}

@article{MTMT:23088590,
	title = {Delta activity as an early indicator for soman-induced brain damage: A review},
	url = {https://m2.mtmt.hu/api/publication/23088590},
	author = {Carpentier, P and Foquin, A and Dorandeu, F and Lallement, G},
	doi = {10.1016/A0161-813X(01)00019-5},
	journal-iso = {NEUROTOXICOLOGY},
	journal = {NEUROTOXICOLOGY},
	volume = {22},
	unique-id = {23088590},
	issn = {0161-813X},
	year = {2001},
	eissn = {1872-9711},
	pages = {299-315}
}

@article{MTMT:2139143,
	title = {Immunotoxicological investigations on rats treated subacutely with dimethoate, As3+ and Hg2+ in combination},
	url = {https://m2.mtmt.hu/api/publication/2139143},
	author = {Institóris, László and Siroki, O and Undeger, U and Basaran, N and Dési, Illés},
	doi = {10.1191/096032701680350569},
	journal-iso = {HUM EXP TOXICOL},
	journal = {HUMAN & EXPERIMENTAL TOXICOLOGY},
	volume = {20},
	unique-id = {2139143},
	issn = {0960-3271},
	abstract = {Effects of combined exposure with dimethoate (DM), HgCl2 (Hg), and NaAsO2 (As) were investigated following a 28 - day oral exposure in male Wistar rats. In preliminary experiments, the LOEL (Lowest Observed Effect Level) and NOEL (Non Observed Effect Level) doses of the substances were determined using the same experimental system [determination of body weight gain, organ weights of brain, thymus, heart, lung, kidneys, adrenals, spleen, testicles, popliteal lymph node, white blood cell (WBC) and red blood cell (RBC) count, haematocrit (Ht), mean cell volume (MCV) of RBCs, cell content of the femoral bone marrow, IgM-plaque forming cell (PFC) content of the spleen, delayed type hypersensitivity (DTH) reaction] and animal strain. In the combination studies, LOEL dose of DM (28.2 mg/kg) was combined with NOEL doses of the heavy metals ( HgCl2 = 0.40 mg/kg, NaAsO2 = 3.33 mg/kg), and vice versa (DM = 7.04 mg/kg, HgCl2 = 3.20 mg/kg, NaAsO2 = 13.3 mg/kg). In the DM-Hg combinations, significant alterations were found versus the corresponding high- dose internal control in the body weight gain, relative liver and kidney weights, and in the PFC response. When DM was combined with As, interactions were indicated by changes of relative liver weight, MCV value, and the PFC content of the spleen. These results support the theory that the interactions between pesticides and heavy metals may modify the toxic effects of the single substances, and may also change the functional detection limits of the exposure. The changes in the functional detection limits, if they occur, can lead to false-positive and false-negative results in human epidemiological studies.},
	keywords = {Animals; Body Weight; Male; TISSUE DISTRIBUTION; RATS; Drug Interactions; weight gain; No-Observed-Adverse-Effect Level; Rats, Wistar; Mercury/analysis/pharmacokinetics/*toxicity; Mercuric Chloride/administration & dosage/pharmacology; Insecticides/analysis/pharmacokinetics/*toxicity; Disinfectants/administration & dosage/pharmacology; Dimethoate/analysis/pharmacokinetics/*toxicity; Arsenic/analysis/pharmacokinetics/*toxicity},
	year = {2001},
	eissn = {1477-0903},
	pages = {329-336}
}

@article{MTMT:23083879,
	title = {Effects of single or repeated dermal exposure to methyl parathion on behavior and blood cholinesterase activity in rats},
	url = {https://m2.mtmt.hu/api/publication/23083879},
	author = {Zhu, H and Rockhold, RW and Baker, RC and Kramer, RE and Ho, IK},
	journal-iso = {J BIOMED SCI},
	journal = {JOURNAL OF BIOMEDICAL SCIENCE},
	volume = {8},
	unique-id = {23083879},
	issn = {1021-7770},
	year = {2001},
	eissn = {1423-0127},
	pages = {467-474}
}

@article{MTMT:2139146,
	title = {Simultaneous geno- and immunotoxicological investigations for early detection of organophosphate toxicity in rats.},
	url = {https://m2.mtmt.hu/api/publication/2139146},
	author = {Undeger, U and Institóris, László and Siroki, O and Nehez, M and Dési, Illés},
	doi = {10.1006/eesa.1999.1844},
	journal-iso = {ECOTOX ENVIRON SAFE},
	journal = {ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY},
	volume = {45},
	unique-id = {2139146},
	issn = {0147-6513},
	abstract = {Detectability of toxic effects by repeated doses of dimethoate (DM) and methylparathion (MPT) were investigated by geno-and immunotoxicological methods in male Wistar rats following a 28-day oral exposure. In the dose range of 28.2, 14.1, and 7.04, and 7.04 mg/kg/day DM, the two higher doses decreased the body weight gain. The top dose increased the weight of liver, kidneys, and testicles; the white blood cell count; and the cell content of the femoral bone marrow. From immune function parameters measured [IgM-plaque forming cells (PFC) assay, delayed-type hypersensitivity (DTH) reaction] only the maximum of the DTH reaction decreased at the top dose. Of the MPT doses (0.872, 0.436, and 0.218 mg/kg/day) the two higher ones increased the liver weight, and a dose-dependent increase was found in the MCV value. No evaluable changes in the examined immune function parameters were observed. Both substances increased the number of numerical but not the structural chromosome aberrations at lower dose levels (the two larger doses of DM, and all the three doses of MPT) than those ones which caused changes in the examined immune function parameters. According to these results, the genotoxicological approach seems to be more sensitive for detection of repeated-dose oral toxicity of the investigated two organophosphates than the immunotoxicological one.},
	keywords = {Animals; Male; RATS; Dose-Response Relationship, Drug; Rats, Wistar; *Chromosome Aberrations; Insecticides/*toxicity; Methyl Parathion/*toxicity; Immune System/*drug effects; Hypersensitivity, Delayed/etiology; Dimethoate/*toxicity; Antibody-Producing Cells/drug effects},
	year = {2000},
	eissn = {1090-2414},
	pages = {43-48}
}

@article{MTMT:2110977,
	title = {Electrophysiological biomarkers of an organophosphorous pesticide, dichlorvos.},
	url = {https://m2.mtmt.hu/api/publication/2110977},
	author = {Dési, Illés and Nagymajtényi, László},
	doi = {10.1016/S0378-4274(99)00031-4},
	journal-iso = {TOXICOL LETT},
	journal = {TOXICOLOGY LETTERS},
	volume = {107},
	unique-id = {2110977},
	issn = {0378-4274},
	year = {1999},
	eissn = {1879-3169},
	pages = {55-64},
	orcid-numbers = {Nagymajtényi, László/0000-0002-7848-4573}
}

@article{MTMT:23083883,
	title = {Nerve agent poisoning in primates: Antilethal, anti-epileptic and neuroprotective effects of GK-11},
	url = {https://m2.mtmt.hu/api/publication/23083883},
	author = {Lallement, G and Clarencon, D and Masqueliez, C and Baubichon, D and Galonnier, M and Burchkhart, M-F and Peoc'h M and Mestries, JC},
	journal-iso = {ARCH TOXICOL},
	journal = {ARCHIVES OF TOXICOLOGY},
	volume = {72},
	unique-id = {23083883},
	issn = {0340-5761},
	year = {1997},
	eissn = {1432-0738},
	pages = {84-92}
}

@article{MTMT:23276904,
	title = {Brain involvement in organophosphate poisoning},
	url = {https://m2.mtmt.hu/api/publication/23276904},
	author = {Yilmazlar, A and Ozyurt, G},
	doi = {10.1006/enrs.1997.3758},
	journal-iso = {ENVIRON RES},
	journal = {ENVIRONMENTAL RESEARCH},
	volume = {74},
	unique-id = {23276904},
	issn = {0013-9351},
	year = {1997},
	eissn = {1096-0953},
	pages = {104-109}
}