@article{MTMT:32312190,
	title = {From genes to shape during metamorphosis: a history},
	url = {https://m2.mtmt.hu/api/publication/32312190},
	author = {Thompson, Barry J.},
	doi = {10.1016/j.cois.2020.08.008},
	journal-iso = {CURR OPIN INSECT SCI},
	journal = {CURRENT OPINION IN INSECT SCIENCE},
	volume = {43},
	unique-id = {32312190},
	issn = {2214-5745},
	abstract = {Metamorphosis (Greek for a state of transcending-form or change-in-shape) refers to a dramatic transformation of an animal's body structure that occurs after development of the embryo or larva in many species. The development of a fly (or butterfly) from a crawling larva (or caterpillar) that forms a pupa (or chrysalis) before eclosing as a flying adult is a classic example of metamorphosis that captures the imagination and has been immortalized in children's books. Powerful genetic experiments in the fruit fly Drosophila melanogaster have revealed how genes can instruct the behaviour of individual cells to control patterns of tissue growth, mechanical force, cell-cell adhesion and cell matrix adhesion drive morphogenetic change in epithelial tissues. Together, the distribution of mass, force and resistance determines cell shape changes, cell-cell rearrangements, and/or the orientation of cell divisions to generate the final form of the tissue. In organising tissue shape, genes harness the power of self-organisation to determine the collective behaviour of molecules and cells, which can often be reproduced in computer simulations of cell polarity and/or tissue mechanics. This review highlights fundamental discoveries in epithelial morphogenesis made by pioneers who were fascinated by metamorphosis, including D'Arcy Thompson, Conrad Waddington, Dianne Fristrom and Antonio Garcia-Bellido.},
	year = {2021},
	eissn = {2214-5753},
	pages = {1-10}
}

@article{MTMT:30913605,
	title = {Investigation of the Developmental Requirements of Drosophila HP1 and Insulator Protein Partner, HIPP1},
	url = {https://m2.mtmt.hu/api/publication/30913605},
	author = {Glenn, Steve E. and Geyer, Pamela K.},
	doi = {10.1534/g3.118.200705},
	journal-iso = {G3-GENES GENOM GENET},
	journal = {G3-GENES GENOMES GENETICS},
	volume = {9},
	unique-id = {30913605},
	issn = {2160-1836},
	abstract = {Drosophila Suppressor of Hairy-wing [Su(Hw)] is a multifunctional zinc finger DNA binding protein. Transcriptional regulation by Su(Hw) is essential in the ovary and testis, where Su(Hw) functions primarily as a repressor. Recently, the HP1a and Insulator Partner Protein 1 (HIPP1) was found to extensively co-localize with Su(Hw) and other insulator binding proteins in euchromatic regions of the genome, and with Heterochromatin Protein 1a (HP1a) in heterochromatic regions. As HIPP1 is the homolog of the human co-repressor Chromodomain Y-Like (CDYL), we tested its requirement in establishing transcriptional repression in flies. To this end, we generated multiple Hipp1 null alleles and a tagged derivative of the endogenous gene (Hipp1(GFP)), using CRISPR mutagenesis. We show that HIPP1 is a widely expressed nuclear protein that is dispensable for viability, as well as female and male fertility. We find that HIPP1 and HP1a display minimum co-localization in interphase cells, and HP1a-dependent transcriptional repression of several reporter genes is HIPP1-independent, indicating that HIPP1 is not essential for HP1a-dependent heterochromatin formation. Despite Su(Hw) having a major role in promoting HIPP1 occupancy in euchromatin, we show that HIPP1 is dispensable for the transcriptional and insulator functions of Su(Hw), indicating that HIPP1 is not a critical Su(Hw) cofactor. Further studies are needed to clarify the role of HIPP1 in Drosophila development.},
	keywords = {DROSOPHILA; TRANSCRIPTIONAL REGULATION; Su(Hw); chromatin insulator, HIPP1, HP1a, corepressor, CDYL},
	year = {2019},
	eissn = {2160-1836},
	pages = {345-357}
}

@article{MTMT:27525173,
	title = {Apical and Basal Matrix Remodeling Control Epithelial Morphogenesis},
	url = {https://m2.mtmt.hu/api/publication/27525173},
	author = {Diaz-de-la-Loza, Maria-del-Carmen and Ray, Robert P and Ganguly, Poulami S and Alt, Silvanus and Davis, John R and Hoppe, Andreas and Tapon, Nic and Salbreux, Guillaume and Thompson, Barry J},
	doi = {10.1016/j.devcel.2018.06.006},
	journal-iso = {DEV CELL},
	journal = {DEVELOPMENTAL CELL},
	volume = {46},
	unique-id = {27525173},
	issn = {1534-5807},
	year = {2018},
	eissn = {1878-1551},
	pages = {23-+}
}

@article{MTMT:24092356,
	title = {Microarray Comparison of Anterior and Posterior Drosophila Wing Imaginal Disc Cells Identifies Novel Wing Genes},
	url = {https://m2.mtmt.hu/api/publication/24092356},
	author = {Ibrahim, DM and Biehs, B and Kornberg, TB and Klebes, A},
	doi = {10.1534/g3.113.006569},
	journal-iso = {G3-GENES GENOM GENET},
	journal = {G3-GENES GENOMES GENETICS},
	volume = {3},
	unique-id = {24092356},
	issn = {2160-1836},
	year = {2013},
	eissn = {2160-1836},
	pages = {1353-1362}
}

@article{MTMT:22080205,
	title = {Overlapping Roles of Drosophila Drak and Rok Kinases in Epithelial Tissue Morphogenesis},
	url = {https://m2.mtmt.hu/api/publication/22080205},
	author = {Neubueser, D and Hipfner, DR},
	doi = {10.1091/mbc.E10-04-0328},
	journal-iso = {MOL BIOL CELL},
	journal = {MOLECULAR BIOLOGY OF THE CELL},
	volume = {21},
	unique-id = {22080205},
	issn = {1059-1524},
	year = {2010},
	eissn = {1939-4586},
	pages = {2869-2879}
}

@article{MTMT:22104048,
	title = {how functions in leg development during Drosophila metamorphosis},
	url = {https://m2.mtmt.hu/api/publication/22104048},
	author = {Fortier, T M and Chatterjee, R and Klinedinst, S and Baehrecke, E H and Woodard, C T},
	doi = {10.1002/dvdy.20852},
	journal-iso = {DEV DYNAM},
	journal = {DEVELOPMENTAL DYNAMICS},
	volume = {235},
	unique-id = {22104048},
	issn = {1058-8388},
	year = {2006},
	eissn = {1097-0177},
	pages = {2248-2259}
}

@article{MTMT:22089526,
	title = {Mutational analysis of stubble-stubbloid gene structure and function in Drosophila leg and bristle morphogenesis},
	url = {https://m2.mtmt.hu/api/publication/22089526},
	author = {Hammonds, AS and Fristrom, JW},
	doi = {10.1534/genetics.105.047100},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {172},
	unique-id = {22089526},
	issn = {0016-6731},
	year = {2006},
	eissn = {1943-2631},
	pages = {1577-1593}
}

@article{MTMT:22192528,
	title = {Interaction between hormonal signaling pathways in Drosophila melanogaster as revealed by genetic interaction between Methoprene-tolerant and Broad-Complex},
	url = {https://m2.mtmt.hu/api/publication/22192528},
	author = {Wilson, TG and Yerushalmi, Y and Donnell, DM and Restifo, L},
	doi = {10.1534/genetics.105.046631},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {172},
	unique-id = {22192528},
	issn = {0016-6731},
	year = {2006},
	eissn = {1943-2631},
	pages = {253-264}
}

@article{MTMT:22104058,
	title = {Ecdysteroid control of metamorphosis in the differentiating adult leg structures of Drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/22104058},
	author = {Mirth, C},
	doi = {10.1016/j.ydbio.2004.10.026},
	journal-iso = {DEV BIOL},
	journal = {DEVELOPMENTAL BIOLOGY},
	volume = {278},
	unique-id = {22104058},
	issn = {0012-1606},
	year = {2005},
	eissn = {1095-564X},
	pages = {163-174}
}

@article{MTMT:22080210,
	title = {Rho-LIM kinase signaling regulates ecdysone-induced gene expression and morphogenesis during Drosophila metamorphosis},
	url = {https://m2.mtmt.hu/api/publication/22080210},
	author = {Chen, GC and Gajowniczek, P and Settleman, J},
	doi = {10.1016/j.cub.2004.01.056},
	journal-iso = {CURR BIOL},
	journal = {CURRENT BIOLOGY},
	volume = {14},
	unique-id = {22080210},
	issn = {0960-9822},
	year = {2004},
	eissn = {1879-0445},
	pages = {309-313}
}

@article{MTMT:22104069,
	title = {Genetic interactions between the RhoA and stubble-stubbloid loci suggest a role for a type II transmembrane serine protease in intracellular signaling during Drosophila imaginal disc morphogenesis},
	url = {https://m2.mtmt.hu/api/publication/22104069},
	author = {Bayer, CA and Halsell, SR and Fristrom, JW and Kiehart, DP and von Kalm, L},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {165},
	unique-id = {22104069},
	issn = {0016-6731},
	year = {2003},
	eissn = {1943-2631},
	pages = {1417-1432}
}

@article{MTMT:22104066,
	title = {Orphan nuclear receptor beta FTZ-F1 is required for muscle-driven morphogenetic events at the prepupal-pupal transition in Drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/22104066},
	author = {Fortier, TA and Vasa, PP and Woodard, CT},
	doi = {10.1016/S0012-1606(03)00036-8},
	journal-iso = {DEV BIOL},
	journal = {DEVELOPMENTAL BIOLOGY},
	volume = {257},
	unique-id = {22104066},
	issn = {0012-1606},
	year = {2003},
	eissn = {1095-564X},
	pages = {153-165}
}

@article{MTMT:22131160,
	title = {Genetic modifier screens in Drosophila demonstrate a role for Rho1 signaling in ecdysone-triggered imaginal disc morphogenesis},
	url = {https://m2.mtmt.hu/api/publication/22131160},
	author = {Ward, RE and Evans, J and Thummel, CS},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {165},
	unique-id = {22131160},
	issn = {0016-6731},
	year = {2003},
	eissn = {1943-2631},
	pages = {1397-1415}
}

@article{MTMT:22080214,
	title = {Gene targeting in hemostasis. Hepsin},
	url = {https://m2.mtmt.hu/api/publication/22080214},
	author = {Wu, QY},
	journal-iso = {FRONT BIOSCI},
	journal = {FRONTIERS IN BIOSCIENCE},
	volume = {6},
	unique-id = {22080214},
	issn = {1093-9946},
	year = {2001},
	eissn = {1093-4715},
	pages = {D192-D200}
}

@article{MTMT:22144053,
	title = {An Enhancer Trap Screen for Ecdysone-Inducible Genes Required for Drosophila Adult Leg Morphogenesis.},
	url = {https://m2.mtmt.hu/api/publication/22144053},
	author = {Gates, J and Thummel, CS},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {156},
	unique-id = {22144053},
	issn = {0016-6731},
	year = {2000},
	eissn = {1943-2631},
	pages = {1765-1776}
}

@article{MTMT:22104103,
	title = {Peptide-Hormones, Steroid-Hormones, and Puffs - Mechanisms and Models in Insect Development.},
	url = {https://m2.mtmt.hu/api/publication/22104103},
	author = {Henrich, VC and Rybczynski, R and Gilbert, LI},
	journal-iso = {VITAM HORM},
	journal = {VITAMINS AND HORMONES-ADVANCES IN RESEARCH AND APPLICATIONS},
	volume = {55},
	unique-id = {22104103},
	issn = {0083-6729},
	year = {1999},
	pages = {73-125}
}

@article{MTMT:22554941,
	title = {Genetic Organization of Polytene Chromosomes.},
	url = {https://m2.mtmt.hu/api/publication/22554941},
	author = {Zhimulev, IF},
	doi = {10.1016/S0065-2660(08)60476-9},
	journal-iso = {ADV GENET},
	journal = {ADVANCES IN GENETICS},
	volume = {39},
	unique-id = {22554941},
	issn = {0065-2660},
	year = {1999},
	pages = {1-589}
}

@article{MTMT:22144125,
	title = {Crooked Legs Encodes a Family of Zinc-Finger Proteins Required for Leg Morphogenesis and Ecdysone-Regulated Gene- Expression During Drosophila Metamorphosis.},
	url = {https://m2.mtmt.hu/api/publication/22144125},
	author = {Davino, PP and Thummel, CS},
	journal-iso = {DEVELOPMENT},
	journal = {DEVELOPMENT},
	volume = {125},
	unique-id = {22144125},
	issn = {0950-1991},
	year = {1998},
	eissn = {1477-9129},
	pages = {1733-1745}
}

@article{MTMT:23392521,
	title = {Generation and characterization of mice deficient in hepsin, a hepatic transmembrane serine protease},
	url = {https://m2.mtmt.hu/api/publication/23392521},
	author = {Wu, QY and Yu, DY and Post, J and Halks-Miller, M and Sadler, JE and Morser, J},
	doi = {10.1172/JCI1617},
	journal-iso = {J CLIN INVEST},
	journal = {JOURNAL OF CLINICAL INVESTIGATION},
	volume = {101},
	unique-id = {23392521},
	issn = {0021-9738},
	year = {1998},
	eissn = {1558-8238},
	pages = {321-326}
}

@article{MTMT:22104129,
	title = {The Making of a Fly Leg - A Model for Epithelial Morphogenesis.},
	url = {https://m2.mtmt.hu/api/publication/22104129},
	author = {Vonkalm, L and Fristrom, D and Fristrom, J},
	doi = {10.1002/bies.950170806},
	journal-iso = {BIOESSAYS},
	journal = {BIOESSAYS},
	volume = {17},
	unique-id = {22104129},
	issn = {0265-9247},
	year = {1995},
	eissn = {1521-1878},
	pages = {693-702}
}

@article{MTMT:22104143,
	title = {Differential Expression of Broad-Complex Transcription Factors May Forecast Tissue-Specific Developmental Fates During Drosophila Metamorphosis.},
	url = {https://m2.mtmt.hu/api/publication/22104143},
	author = {Emery, IF and Bedian, V and Guild, GM},
	journal-iso = {DEVELOPMENT},
	journal = {DEVELOPMENT},
	volume = {120},
	unique-id = {22104143},
	issn = {0950-1991},
	year = {1994},
	eissn = {1477-9129},
	pages = {3275-3287}
}

@article{MTMT:22104144,
	title = {2 Drosophila Regulatory Genes, Deformed and the Broad- Complex, Share Common Functions in Development of Adult CNS, Head, and Salivary-Glands.},
	url = {https://m2.mtmt.hu/api/publication/22104144},
	author = {Restifo, LL and Merrill, VKL},
	doi = {10.1006/dbio.1994.1102},
	journal-iso = {DEV BIOL},
	journal = {DEVELOPMENTAL BIOLOGY},
	volume = {162},
	unique-id = {22104144},
	issn = {0012-1606},
	year = {1994},
	eissn = {1095-564X},
	pages = {465-485}
}

@article{MTMT:23392522,
	title = {THE DROSOPHILA STUBBLE-STUBBLOID GENE ENCODES AN APPARENT TRANSMEMBRANE SERINE-PROTEASE REQUIRED FOR EPITHELIAL MORPHOGENESIS},
	url = {https://m2.mtmt.hu/api/publication/23392522},
	author = {APPEL, LF and PROUT, M and ABUSHUMAYS, R and HAMMONDS, A and GARBE, JC and FRISTROM, D and FRISTROM, J},
	doi = {10.1073/pnas.90.11.4937},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {90},
	unique-id = {23392522},
	issn = {0027-8424},
	year = {1993},
	eissn = {1091-6490},
	pages = {4937-4941}
}

@article{MTMT:22080225,
	title = {Cytogenetic Analysis of Chromosome Region-89A of Drosophila-Melanogaster - Isolation of Deficiencies and Mapping of Po, Aldox-1 and Transposon Insertions.},
	url = {https://m2.mtmt.hu/api/publication/22080225},
	author = {Nelson, CR and Szauter, P},
	doi = {10.1007/BF00286176},
	journal-iso = {MOL GEN GENET},
	journal = {MOLECULAR & GENERAL GENETICS},
	volume = {235},
	unique-id = {22080225},
	issn = {0026-8925},
	year = {1992},
	eissn = {1432-1874},
	pages = {11-21}
}

@article{MTMT:25752344,
	title = {MUTATIONS IN A STEROID HORMONE-REGULATED GENE DISRUPT THE METAMORPHOSIS OF INTERNAL TISSUES IN DROSOPHILA - SALIVARY-GLANDS, MUSCLE, AND GUT},
	url = {https://m2.mtmt.hu/api/publication/25752344},
	author = {RESTIFO, LL and WHITE, K},
	doi = {10.1007/BF00188753},
	journal-iso = {ROUX ARCH DEV BIOL},
	journal = {ROUXS ARCHIVES OF DEVELOPMENTAL BIOLOGY},
	volume = {201},
	unique-id = {25752344},
	issn = {0930-035X},
	year = {1992},
	pages = {221-234}
}

@article{MTMT:22089540,
	title = {Apical Cell-Shape Changes During Drosophila Imaginal Leg Disk Elongation - A Novel Morphogenetic Mechanism.},
	url = {https://m2.mtmt.hu/api/publication/22089540},
	author = {Condic, ML and Fristrom, D and Fristrom, JW},
	journal-iso = {DEVELOPMENT},
	journal = {DEVELOPMENT},
	volume = {111},
	unique-id = {22089540},
	issn = {0950-1991},
	year = {1991},
	eissn = {1477-9129},
	pages = {23-33}
}

@article{MTMT:22104163,
	title = {3 Neighboring Genes Interact with the Broad-Complex and the Stubble-Stubbloid Locus to Affect Imaginal Disk Morphogenesis in Drosophila.},
	url = {https://m2.mtmt.hu/api/publication/22104163},
	author = {Gotwals, PJ and Fristrom, JW},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {127},
	unique-id = {22104163},
	issn = {0016-6731},
	year = {1991},
	eissn = {1943-2631},
	pages = {747-759}
}

@article{MTMT:22104157,
	title = {The Ecdysone-Induced Puffing Cascade in Drosophila Salivary-Glands - A Broad-Complex Early Gene Regulates Intermolt and Late Gene-Transcription.},
	url = {https://m2.mtmt.hu/api/publication/22104157},
	author = {Guay, PS and Guild, GM},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {129},
	unique-id = {22104157},
	issn = {0016-6731},
	year = {1991},
	eissn = {1943-2631},
	pages = {169-175}
}

@article{MTMT:22104161,
	title = {Mutations in a Steroid Hormone-Regulated Gene Disrupt the Metamorphosis of the Central-Nervous-System in Drosophila.},
	url = {https://m2.mtmt.hu/api/publication/22104161},
	author = {Restifo, LL and White, K},
	doi = {10.1016/0012-1606(91)90328-Z},
	journal-iso = {DEV BIOL},
	journal = {DEVELOPMENTAL BIOLOGY},
	volume = {148},
	unique-id = {22104161},
	issn = {0012-1606},
	year = {1991},
	eissn = {1095-564X},
	pages = {174-194}
}

@article{MTMT:22080230,
	title = {Gene-Expression in Adult Metafemales of Drosophila-Melanogaster.},
	url = {https://m2.mtmt.hu/api/publication/22080230},
	author = {Birchler, JA and Hiebert, JC and Krietzman, M},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {122},
	unique-id = {22080230},
	issn = {0016-6731},
	year = {1989},
	eissn = {1943-2631},
	pages = {869-879}
}

@article{MTMT:1904570,
	title = {Interactions and developmental effects of mutations at the 2B5 locus of Drosophila melanogaster.},
	url = {https://m2.mtmt.hu/api/publication/1904570},
	author = {Kiss, István and BEATON, AH and TARDIFF, J and FRISTROM, D and FRISTROM, JW},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {118},
	unique-id = {1904570},
	issn = {0016-6731},
	year = {1988},
	eissn = {1943-2631},
	pages = {247-259}
}