TY  - JOUR
AU  - Dixon, John B
AU  - Strauss, Boyd J G
AU  - Laurie, Cheryl
AU  - O'Brien, Paul E
TI  - Changes in body composition with weight loss: Obese subjects randomized to surgical and medical programs
JF  - OBESITY
J2  - OBESITY
VL  - 15
PY  - 2007
IS  - 5
SP  - 1187
EP  - 1198
PG  - 12
SN  - 1930-7381
DO  - 10.1038/oby.2007.639
UR  - https://m2.mtmt.hu/api/publication/24822108
ID  - 24822108
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Lakatos, Péter
AU  - Földes, János
AU  - Horváth, Csaba
AU  - Kiss, L
AU  - Tatrai, A
AU  - Takács, István
AU  - Tarjan, G
AU  - Stern, P H
TI  - Serum interleukin-6 and bone metabolism in patients with thyroid function disorders
JF  - JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
J2  - J CLIN ENDOCR METAB
VL  - 82
PY  - 1997
IS  - 1
SP  - 78
EP  - 81
PG  - 4
SN  - 0021-972X
DO  - 10.1210/jcem.82.1.3641
UR  - https://m2.mtmt.hu/api/publication/1802122
ID  - 1802122
N1  - Összes idézések száma a WoS-ban: 0
1st Department of Medicine, Semmelweis University Medical School, Budapest, H-1083, Hungary            
            Hetenyi Geza County Hospital, Szolnok, H-5000, Hungary            
            Dept. Molec. Pharmacol. Biol. Chem., NW University Medical School, Chicago, IL 60611, United States            
            1st Department of Medicine, Semmelweis University Medical School, Koranyi 2/A, Budapest, H-1083, Hungary            
            Cited By :72            
            Export Date: 13 March 2020            
            CODEN: JCEMA            
            Correspondence Address: Lakatos, P.; 1st Department of Medicine, Semmelweis University Medical School, Koranyi 2/A, Budapest H-1083, Hungary            
            Chemicals/CAS: Amino Acids; deoxypyridinoline, 90032-33-0; Interleukin-6; Osteocalcin, 104982-03-8
AB  - To determine the possible involvement of interleukin-6(IL-6) in the bone loss of hyperthyroidism, relationships between thyroid status, biochemical and densitometric parameters of bone metabolism, and IL-6 were studied in female subjects. Patients with hyperthyroidism caused by either toxic nodular goiter or Graves' disease had significantly higher serum IL-6 concentrations than normal controls. Within the control group, serum IL-6 was higher in postmenopausal than in premenopausal women, but this influence of menopausal status was not seen in the hyperthyroid patients. The production of IL-6 by blood mononuclear cells was higher in cells from the hyperthyroid women. Bone turnover was increased in the hyperthyroid patients based on serum osteocalcin and urinary deoxypyridinoline excretion, and the hyperthyroid group also had reduced radius bone mineral content (BMC). A subgroup of hyperthyroid patients who had the lowest BMC (values more than 1 SD below normal age-matched controls) also had serum IL-6 concentrations significantly greater than those of hyperthyroid patients showing less reduction of BMC. The correlations observed in this study support the possibility that IL-6 plays a role in mediating the bone loss that results from excess thyroid hormone.
LA  - English
DB  - MTMT
ER  -