TY - JOUR AU - Liu, Bin -Bin AU - Niu, Zi-Ru AU - Jia, Xiao-Jiao AU - Liu, Xiao-Li AU - Lu, Qiang TI - Correlation between Insulin Resistance and Cardiopulmonary Function during Physical Exams for Male Patients JF - AMERICAN JOURNAL OF HEALTH BEHAVIOR J2 - AM J HEALTH BEHAV VL - 46 PY - 2022 IS - 6 SP - 600 EP - 605 PG - 6 SN - 1087-3244 DO - 10.5993/AJHB.46.6.2 UR - https://m2.mtmt.hu/api/publication/33861749 ID - 33861749 AB - Objective: In this study, we investigated the correlation between insulin resistance (IR) and cardiopulmonary function during physical exams for male patients.Methods: We selected 124 healthy male participants in the physical examination center of our hospital. They were divided into 3 groups according to the homeostasis model assessment of insulin resistance values. The oxygen uptake, peak oxygen uptake (VO2/kg), heart rate, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured by a cardiopulmonary exercise function tester. We analyzed the correlation between the index of IR and cardiopulmonary function.Results: There were statistically significant differences in body mass index, waist circumference, fasting insulin level, anaerobic threshold SBP, maximum VO2/kg and maximum SBP among the 3 groups (p<.05). However, no significant difference was found in SBP, DBP, total cholesterol, low-density lipoprotein cholesterol and fasting blood glucose levels (p>.05). The anaerobic threshold SBP, maximum VO2/kg and maximum SBP were all negatively correlated with the IR index.Conclusion: Our results indicate that IR is associated with cardiopulmonary function and that there are different correlations between the various cardiopulmonary function indexes and IR. LA - English DB - MTMT ER - TY - JOUR AU - Bokova, T.A. TI - Risk factors for metabolic syndrome in obese children JF - ROSSIISKII VESTNIK PERINATOLOGII I PEDIATRII J2 - ROSSIISKII VESTNIK PERINATOLOGII I PEDIATRII VL - 63 PY - 2018 IS - 3 SP - 64 EP - 69 PG - 6 SN - 1027-4065 DO - 10.21508/1027-4065-2018-63-3-64-69 UR - https://m2.mtmt.hu/api/publication/32459207 ID - 32459207 N1 - Export Date: 18 October 2021 Correspondence Address: Bokova, T.A.; Moscow Regional Research and Clinical Institute named after M.F. VladimirskiyRussian Federation LA - Russian DB - MTMT ER - TY - BOOK AU - Parízková, J. TI - Nutrition, physical activity, and health in early life, second edition PB - CRC Press CY - Boca Raton, Florida PY - 2016 SP - 1 EP - 428 SP - 428 SN - 9781420082357 UR - https://m2.mtmt.hu/api/publication/32459208 ID - 32459208 N1 - Export Date: 18 October 2021 Correspondence Address: Parízková, J.; Centre for the Management of Obesity, Czech Republic LA - English DB - MTMT ER - TY - JOUR AU - Wycherley, TP AU - Buckley, JD AU - Noakes, M AU - Clifton, PM AU - Brinkworth, GD TI - Comparison of the effects of weight loss from a high-protein versus standard-protein energy-restricted diet on strength and aerobic capacity in overweight and obese men JF - EUROPEAN JOURNAL OF NUTRITION J2 - EUR J NUTR VL - 52 PY - 2013 IS - 1 SP - 317 EP - 325 PG - 9 SN - 1436-6207 DO - 10.1007/s00394-012-0338-0 UR - https://m2.mtmt.hu/api/publication/23255849 ID - 23255849 N1 - : manny/H-2813-2013 LA - English DB - MTMT ER - TY - CHAP AU - Nadeau, K AU - Reusch, JEB AU - Regensteiner, JG ED - Regensteiner, JG ED - Reusch, JEB ED - Stewart, KJ ED - Veves, A TI - Exercise and Type 2 Diabetes in Youth T2 - DIABETES AND EXERCISE PB - Humana Press CY - Totowa (NJ) SN - 9781588299260 T3 - Contemporary Diabetes PB - Humana Press PY - 2009 SP - 301 EP - 310 PG - 10 DO - 10.1007/978-1-59745-260-1_15 UR - https://m2.mtmt.hu/api/publication/22866389 ID - 22866389 N1 - D2 10.1007/978-1-59745-260-1 LA - English DB - MTMT ER - TY - JOUR AU - Nadeau, KJ AU - Zeitler, PS AU - Bauer, TA AU - Brown, MS AU - Dorosz, JL AU - Draznin, B AU - Reusch, JEB AU - Regensteiner, JG TI - Insulin Resistance in Adolescents with Type 2 Diabetes Is Associated with Impaired Exercise Capacity JF - JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM J2 - J CLIN ENDOCR METAB VL - 94 PY - 2009 IS - 10 SP - 3687 EP - 3695 PG - 9 SN - 0021-972X DO - 10.1210/jc.2008-2844 UR - https://m2.mtmt.hu/api/publication/23255850 ID - 23255850 N1 - Funding Agency and Grant Number: National Institutes of Health (NIH/NCRR) [1 K23 RR020038-01, F32DK078413-01]; Department of Veterans Affairs; National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health [5 U01 DK61242-02]; NIH [DK-64741, HL56481, DK 57516]; American Diabetes Association; Adult General Clinical Research Center NIH [M01-RR00051]; Pediatric Clinical Translational Research Center NIH [5MO1 RR00069]; NATIONAL CENTER FOR RESEARCH RESOURCES [M01RR000051, K23RR020038, M01RR000069] Funding Source: NIH RePORTER; NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [U01DK061242, P30DK057516, R01DK064741, F32DK078413] Funding Source: NIH RePORTER Funding text: K.J.N. is supported by a career development award from the National Institutes of Health (NIH/NCRR 1 K23 RR020038-01). T. A. B. was supported by NIH Postdoctoral Fellowship Grant F32DK078413-01. B. D. is supported by a Merit Review Award from the Department of Veterans Affairs. P.S.Z. is supported by a cooperative research project grant from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health (5 U01 DK61242-02). J.E.B.R. is supported by Veterans Affairs merit review, NIH DK-64741, HL56481, and DK 57516. J.G.R. is supported by an American Diabetes Association Award. This research was also supported by Adult General Clinical Research Center NIH Grant M01-RR00051 and by Pediatric Clinical Translational Research Center NIH Grant 5MO1 RR00069.We thank our study participants for their time and efforts and Vermed, Inc., for providing exercise electrodes. We also thank Gerald Reaven, Lindsay Ehlers, Leah Herlache, Lisa Herbert, Erik Sorenson, and Amber Hull. LA - English DB - MTMT ER - TY - JOUR AU - Thomson, RL AU - Buckley, JD AU - Moran, LJ AU - Noakes, M AU - Clifton, PM AU - Norman, RJ AU - Brinkworth, GD TI - Comparison of aerobic exercise capacity and muscle strength in overweight women with and without polycystic ovary syndrome JF - BJOG: AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY J2 - BJOG: INT J OBSTET GY VL - 116 PY - 2009 IS - 9 SP - 1242 EP - 1250 PG - 9 SN - 1470-0328 DO - 10.1111/j.1471-0528.2009.02177.x UR - https://m2.mtmt.hu/api/publication/23255851 ID - 23255851 N1 - : Robert/A-1155-2007; Brinkworth, Grant/H-2815-2013; noakes, : manny/H-2813-2013 LA - English DB - MTMT ER - TY - JOUR AU - Brufani, C AU - Grossi, A AU - Fintini, D AU - Fiori, R AU - Ubertini, G AU - Colabianchi, D AU - Ciampalini, P AU - Tozzi, A AU - Barbetti, F AU - Cappa, M TI - Cardiovascular Fitness, Insulin Resistance and Metabolic Syndrome in Severely Obese Prepubertal Italian Children JF - HORMONE RESEARCH J2 - HORM RES VL - 70 PY - 2008 IS - 6 SP - 349 EP - 356 PG - 8 SN - 0301-0163 DO - 10.1159/000161865 UR - https://m2.mtmt.hu/api/publication/23255852 ID - 23255852 N1 - Endocrinology and Diabetes Unit, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy Epidemiology Unit, Department of Paediatric Medicine, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy Department of Internal Medicine, University of Tor Vergata, Rome, Italy Bambino Gesù Children's Hospital-IRCCS, Department of Paediatric Medicine, Endocrinology and Diabetes Unit, Piazza S. Onofrio 4, IT-00165 Rome, Italy Cited By :7 Export Date: 3 November 2020 CODEN: HRMRA Correspondence Address: Brufani, C.; Bambino Gesù Children's Hospital-IRCCS, Department of Paediatric Medicine, Endocrinology and Diabetes Unit, Piazza S. Onofrio 4, IT-00165 Rome, Italy; email: cbrufani@libero.it LA - English DB - MTMT ER - TY - CHAP AU - Wareham, NJ AU - Brage, S AU - Franks, PW AU - Abbott, RA TI - Physical Activity and Insulin Resistance T2 - Insulin Resistance: Insulin Action and Its Disturbances in Disease PB - John Wiley & Sons SN - 9780470011324 PB - John Wiley & Sons PY - 2005 SP - 317 EP - 400 PG - 84 DO - 10.1002/0470011327.ch12 UR - https://m2.mtmt.hu/api/publication/26773730 ID - 26773730 LA - English DB - MTMT ER - TY - JOUR AU - Barbosa, e Silva O AU - Ribeiro, Saraiva LC TI - Exercise test indications in children and adolescents JF - REVISTA BRASILEIRA DE MEDICINA DO ESPORTE J2 - REV BRAS MED ESPORTE VL - 10 PY - 2004 IS - 5 SP - 420 EP - 423 PG - 4 SN - 1517-8692 UR - https://m2.mtmt.hu/api/publication/23573631 ID - 23573631 LA - English DB - MTMT ER - TY - JOUR AU - Dóber, Ilona TI - A gyermekkori kövérség JF - GYERMEKORVOS TOVÁBBKÉPZÉS J2 - GYERMEKORVOS TOVÁBBKÉPZÉS VL - 3 PY - 2004 IS - 1 SP - 40 EP - 45 PG - 6 SN - 1589-0309 UR - https://m2.mtmt.hu/api/publication/24445519 ID - 24445519 N1 - N1 Bibliogr.: p. 45. - Abstr. hun. LA - English DB - MTMT ER - TY - JOUR AU - Decsi, Tamás AU - Molnár, Dénes TI - Insulin resistance syndrome in children : pathophysiology and potential management strategies. JF - PEDIATRIC DRUGS J2 - PEDIATR DRUGS VL - 5 PY - 2003 IS - 5 SP - 291 EP - 299 PG - 9 SN - 1174-5878 DO - 10.2165/00148581-200305050-00002 UR - https://m2.mtmt.hu/api/publication/1439377 ID - 1439377 AB - The simultaneous presence of various cardiovascular risk factors in the same individual is not rare, even in the pediatric age group. The clustering of risk factors can be termed insulin resistance syndrome (IRS) because of the putative central role of tissue insulin insensitivity in the background of the inter-related metabolic disturbances. Fasting hyperinsulinemia, impaired glucose tolerance, dyslipidemia, and hypertension are considered to represent the basic abnormalities of IRS. The most prevalent related disturbances are increased plasma levels of plasminogen activator inhibitor-1, fibrinogen, uric acid, homocysteine, and C-reactive protein, as well as visceral adiposity, microalbuminuria, disturbed essential fatty acid metabolism, low availability of lipid-soluble antioxidant vitamins, and enhanced expression of tumor necrosis factor-alpha in adipose tissues. Certain genetic abnormalities have been associated with IRS, but explain only a small part of the variability in insulin resistance. The exact prevalence of IRS in children remains to be defined; it was found to be 9% in one survey among children with obesity seeking medical attention. Modification of lifestyle, i.e. reduction of energy intake and enhancement of physical activity, are unquestionable prerequisites for long-term success in the management of IRS. In at least two randomized controlled studies, metformin proved to be clinically effective in increasing insulin sensitivity in hyperinsulinemic, nondiabetic adolescents. Thiazolidinediones have been successfully tested for the treatment of insulin resistance in adults, but not in children as yet. Prevention of the development of IRS in children is obviously of great significance for the health status of the community. However, the efficacy of various preventive approaches should be investigated further in carefully designed controlled trials. 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