{ "labelLang" : "hun", "responseDate" : "2024-03-28 14:55", "paging" : { "last" : true, "first" : true, "totalPages" : 1, "totalElements" : 24, "totalUncutElements" : 24, "totalEstimatedElements" : 10, "size" : 100, "number" : 1, "numberOfElements" : 24, "sort" : [ { "direction" : "DESC", "property" : "publishedYear", "ascending" : false }, { "direction" : "ASC", "property" : "firstAuthor", "ascending" : true }, { "direction" : "ASC", "property" : "title", "ascending" : true } ] }, "content" : [ { "otype" : "JournalArticle", "mtid" : 34592013, "status" : "VALIDATED", "published" : true, "comment" : "Export Date: 28 February 2024; CODEN: PHGEF", "unhandledTickets" : 0, "deleted" : false, "lastRefresh" : "2024-03-01T10:34:04.815+0000", "lastModified" : "2024-02-15T15:49:29.050+0000", "created" : "2024-02-15T15:49:27.610+0000", "creator" : { "otype" : "Admin", "mtid" : 521, "link" : "/api/admin/521", "label" : "Szuper Admin (admin)", "familyName" : "Szuper", "givenName" : "Admin", "published" : true, "snippet" : true }, "lastDuplumSearch" : "2024-02-28T11:35:12.979+0000", "validated" : "2024-02-15T15:49:28.114+0000", "validator" : { "otype" : "Admin", "mtid" : 521, "link" : "/api/admin/521", "label" : "Szuper Admin (admin)", "familyName" : "Szuper", "givenName" : "Admin", "published" : true, "snippet" : true }, "core" : false, "citation" : true, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "subType" : { "otype" : "SubType", "mtid" : 1134514, "link" : "/api/subtype/1134514", "label" : "Összefoglaló cikk (Folyóiratcikk)", "name" : "Összefoglaló cikk", "nameEng" : "Survey paper", "docType" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "listPosition" : 102, "published" : true, "oldId" : 1134514, "snippet" : true }, "category" : { "otype" : "Category", "mtid" : 1, "link" : "/api/category/1", "label" : "Tudományos", "published" : true, "oldId" : 1, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10002, "link" : "/api/language/10002", "label" : "Angol", "name" : "Angol", "nameEng" : "English", "published" : true, "oldId" : 2, "snippet" : true } ], "firstAuthor" : "Tan, Yifan", "authorships" : [ { "otype" : "PersonAuthorship", "mtid" : 114489930, "link" : "/api/authorship/114489930", "label" : "Tan, Yifan", "listPosition" : 1, "share" : 0.33333334, "first" : true, "last" : false, "corresponding" : false, "familyName" : "Tan", "givenName" : "Yifan", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 114489931, "link" : "/api/authorship/114489931", "label" : "Chrysopoulou, Maria", "listPosition" : 2, "share" : 0.33333334, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Chrysopoulou", "givenName" : "Maria", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 114489932, "link" : "/api/authorship/114489932", "label" : "Rinschen, Markus M. ✉", "listPosition" : 3, "share" : 0.33333334, "first" : false, "last" : true, "corresponding" : true, "familyName" : "Rinschen", "givenName" : "Markus M.", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true } ], "title" : "Integrative physiology of lysine metabolites", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 25517040, "link" : "/api/publicationidentifier/25517040", "label" : "DOI: 10.1152/physiolgenomics.00061.2023", "source" : { "otype" : "PlainSource", "mtid" : 6, "link" : "/api/publicationsource/6", "label" : "DOI", "type" : { "otype" : "PublicationSourceType", "mtid" : 10001, "link" : "/api/publicationsourcetype/10001", "label" : "DOI", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "DOI", "nameEng" : "DOI", "linkPattern" : "https://doi.org/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 6, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "10.1152/physiolgenomics.00061.2023", "realUrl" : "https://doi.org/10.1152/physiolgenomics.00061.2023", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 25517039, "link" : "/api/publicationidentifier/25517039", "label" : "WoS: 001108027600001", "source" : { "otype" : "PlainSource", "mtid" : 1, "link" : "/api/publicationsource/1", "label" : "WoS", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "WoS", "nameEng" : "WoS", "linkPattern" : "https://www.webofscience.com/wos/woscc/full-record/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 1, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "001108027600001", "realUrl" : "https://www.webofscience.com/wos/woscc/full-record/001108027600001", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 25757153, "link" : "/api/publicationidentifier/25757153", "label" : "Scopus: 85177453206", "source" : { "otype" : "PlainSource", "mtid" : 3, "link" : "/api/publicationsource/3", "label" : "Scopus", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "Scopus", "linkPattern" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@", "publiclyVisible" : true, "published" : true, "oldId" : 3, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "85177453206", "realUrl" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85177453206", "published" : false, "snippet" : true } ], "journal" : { "otype" : "Journal", "mtid" : 31179, "link" : "/api/journal/31179", "label" : "PHYSIOLOGICAL GENOMICS 1094-8341 1531-2267", "pIssn" : "1094-8341", "eIssn" : "1531-2267", "reviewType" : "REVIEWED", "noIF" : false, "sciIndexed" : true, "scopusIndexed" : true, "lang" : "FOREIGN", "hungarian" : false, "published" : true, "oldId" : 31179, "snippet" : true }, "volume" : "55", "issue" : "12", "firstPage" : "579", "lastPage" : "586", "firstPageOrInternalIdForSort" : "579", "pageLength" : 8, "publishedYear" : 2023, "abstractText" : "Lysine is an essential amino acid that serves as a building block in protein synthesis. Beside this, the metabolic activity of lysine has only recently been unraveled. Lysine metabolism is tissue specific and is linked to several renal, cardiovascular, and endocrinological diseases through human metabolomics datasets. As a free molecule, lysine takes part in the antioxidant response and engages in protein modifications, and its chemistry shapes both proteome and metabolome. In the proteome, it is an acceptor for a plethora of posttranslational modifications. In the metabolome, it can be modified, conjugated, and degraded. Here, we provide an update on integrative physiology of mammalian lysine metabolites such as alpha-aminoadipic acid, saccharopine, pipecolic acid, and lysine conjugates such as acetyl-lysine, and sugar-lysine conjugates such as advanced glycation end products. We also comment on their emerging associative and mechanistic links to renal disease, hypertension, diabetes, and cancer.", "subjects" : [ { "otype" : "Classification", "mtid" : 12125, "link" : "/api/classification/12125", "label" : "Általános orvostudomány", "published" : true, "snippet" : true }, { "otype" : "Classification", "mtid" : 10545, "link" : "/api/classification/10545", "label" : "Biológiai tudományok", "published" : true, "snippet" : true } ], "keywords" : [ { "otype" : "Keyword", "mtid" : 334, "link" : "/api/keyword/334", "label" : "metabolism", "published" : true, "oldId" : 334, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1573, "link" : "/api/keyword/1573", "label" : "LYSINE", "published" : true, "oldId" : 1573, "snippet" : true } ], "digital" : null, "printed" : null, "sourceYear" : 2024, "foreignEdition" : true, "foreignLanguage" : true, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : null, "missingAuthor" : false, "oaType" : "NONE", "oaCheckDate" : "2024-03-01", "oaFree" : false, "citationCount" : 0, "citationCountUnpublished" : 0, "citationCountWoOther" : 0, "independentCitCountWoOther" : 0, "doiCitationCount" : 0, "wosCitationCount" : 0, "scopusCitationCount" : 0, "independentCitationCount" : 0, "unhandledCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "unhandledCitingPubCount" : 0, "citedPubCount" : 4, "citedCount" : 4, "ratings" : [ { "otype" : "SjrRating", "mtid" : 11408411, "link" : "/api/sjrrating/11408411", "label" : "sjr:Q1 (2023) Scopus - Physiology PHYSIOLOGICAL GENOMICS 1094-8341 1531-2267", "listPos" : 44, "rankValue" : 0.24, "type" : "journal", "ratingType" : { "otype" : "RatingType", "mtid" : 10002, "link" : "/api/ratingtype/10002", "label" : "sjr", "code" : "sjr", "published" : true, "snippet" : true }, "subject" : { "otype" : "ClassificationExternal", "mtid" : 1314, "link" : "/api/classificationexternal/1314", "label" : "Scopus - Physiology", "published" : true, "oldId" : 1314, "snippet" : true }, "ranking" : "Q1", "calculation" : "FROM_LAST_YEAR", "published" : true, "snippet" : true } ], "ratingsForSort" : "Q1", "hasCitationDuplums" : false, "directInstitutesForSort" : "", "ownerAuthorCount" : 8, "ownerInstituteCount" : 15, "directInstituteCount" : 0, "authorCount" : 3, "contributorCount" : 0, "hasQualityFactor" : true, "link" : "/api/publication/34592013", "label" : "Tan Yifan et al. Integrative physiology of lysine metabolites. (2023) PHYSIOLOGICAL GENOMICS 1094-8341 1531-2267 55 12 579-586", "template" : "