@article{MTMT:33759452,
	title = {Excitatory synchronization of rat hippocampal interneurons during network activation in vitro},
	url = {https://m2.mtmt.hu/api/publication/33759452},
	author = {Pendeliuk, V.S. and Melnick, I.V.},
	doi = {10.3389/fncel.2023.1129991},
	journal-iso = {FRONT CELL NEUROSCI},
	journal = {FRONTIERS IN CELLULAR NEUROSCIENCE},
	volume = {17},
	unique-id = {33759452},
	issn = {1662-5102},
	abstract = {Introduction: Hippocampal interneurons (INs) are known to synchronize their electrical activity via mechanisms, which are poorly defined due to immense complexity of neural tissue but seem to depend on local cell interactions and intensity of network activity. Methods: Here, synchronization of INs was studied using paired patch-clamp recordings in a simplified culture model with intact glutamate transmission. The level of network activity was moderately elevated by field electric stimulation, which is probably an analogue of afferent processing in situ. Results: Even in baseline conditions, ∼45% of spontaneous inhibitory postsynaptic currents (sIPSCs) resulting from firing of individual presynaptic INs coincided between cells within ±1 ms due to simple divergence of inhibitory axons. Brief network activation induced an appearance of ‘hypersynchronous’ (∼80%) population sIPSCs occurring in response to coherent discharges of several INs with jitter ±4 ms. Notably, population sIPSCs were preceded by transient inward currents (TICs). Those were excitatory events capable to synchronize firing of INs, in this respect being reminiscent of so-called fast prepotentials observed in studies on pyramidal neurons. TICs also had network properties consisting of heterogeneous components: glutamate currents, local axonal and dendritic spikelets, and coupling electrotonic currents likely via gap junctions; putative excitatory action of synaptic gamma-aminobutyric acid (GABA) was not involved. The appearance of population excitatory-inhibitory sequences could be initiated and reproduced by firing of a single excitatory cell reciprocally connected with one IN. Discussion: Our data demonstrate that synchronization of INs is initiated and dominated by glutamatergic mechanisms, which recruit, in a whole-sale manner, into supporting action other excitatory means existing in a given neural system. Copyright © 2023 Pendeliuk and Melnick.},
	keywords = {glutamate; hippocampus; hippocampus; ARTICLE; DEPOLARIZATION; MEMBRANE DEPOLARIZATION; Electrophysiology; GABA; nonhuman; brain electrophysiology; Electroencephalography; tetrodotoxin; synaptic transmission; synaptic transmission; excitatory postsynaptic potential; spike wave; electrostimulation; electric activity; action potential; synapse; DENDRITE; SYNCHRONIZATION; chemical structure; nerve cell plasticity; 4 aminobutyric acid; interneuron; Transient transfection; postsynaptic potential; nerve cell excitability; hyperpolarization; gap junctions; cross coupling reaction; patch clamp technique; voltage clamp technique; spikelet; rat; heart ventricle conduction; decapitation; interneurons},
	year = {2023},
	eissn = {1662-5102}
}

@article{MTMT:32821007,
	title = {Quantification of neuron types in the rodent hippocampal formation by data mining and numerical optimization},
	url = {https://m2.mtmt.hu/api/publication/32821007},
	author = {Attili, S.M. and Moradi, K. and Wheeler, D.W. and Ascoli, G.A.},
	doi = {10.1111/ejn.15639},
	journal-iso = {EUR J NEUROSCI},
	journal = {EUROPEAN JOURNAL OF NEUROSCIENCE},
	volume = {55},
	unique-id = {32821007},
	issn = {0953-816X},
	abstract = {Quantifying the population sizes of distinct neuron types in different anatomical regions is an essential step towards establishing a brain cell census. Although estimates exist for the total neuronal populations in different species, the number and definition of each specific neuron type are still intensively investigated. Hippocampome.org is an open-source knowledge base with morphological, physiological and molecular information for 122 neuron types in the rodent hippocampal formation. While such framework identifies all known neuron types in this system, their relative abundances remain largely unknown. This work quantitatively estimates the counts of all Hippocampome.org neuron types by literature mining and numerical optimization. We report the number of neurons in each type identified by main neurotransmitter (glutamate or GABA) and axonal-dendritic patterns throughout 26 subregions and layers of the dentate gyrus, Ammon's horn, subiculum and entorhinal cortex. We produce by sensitivity analysis reliable numerical ranges for each type and summarize the amounts across broad neuronal families defined by biomarkers expression and firing dynamics. Study of density distributions indicates that the number of dendritic-targeting interneurons, but not of other neuronal classes, is independent of anatomical volumes. All extracted values, experimental evidence and related software code are released on Hippocampome.org. © 2022 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.},
	keywords = {Animals; Humans; NEURONS; metabolism; hippocampus; hippocampus; hippocampus; ARTICLE; MOUSE; human; animal; Cell Count; physiology; Sensitivity analysis; controlled study; nonhuman; animal experiment; animal cell; quantitative analysis; brain region; ENTORHINAL CORTEX; ENTORHINAL CORTEX; ENTORHINAL CORTEX; nerve cell; nerve cell; biological marker; dentate gyrus; neurotransmission; glutamic acid; protein expression; data mining; data mining; data mining; process optimization; Rodentia; 4 aminobutyric acid; interneuron; Dendritic cell; rodent; rodent; neuroanatomy; Operations research; firing rate; subiculum; neuroinformatics; Cell census; hippocampome.Org},
	year = {2022},
	eissn = {1460-9568},
	pages = {1724-1741}
}

@article{MTMT:32882089,
	title = {GABA(B)- and GABA(A)-receptor-mediated regulation of Up and Down states across development},
	url = {https://m2.mtmt.hu/api/publication/32882089},
	author = {Kaplanian, Ani and Vinos, Michael and Skaliora, Irini},
	doi = {10.1113/JP282736},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {600},
	unique-id = {32882089},
	issn = {0022-3751},
	abstract = {Slow oscillations, the hallmark of non-REM sleep, and their cellular counterpart, Up and Down states (UDSs), are considered a signature of cortical dynamics that reflect the intrinsic network organization. Although previous studies have explored the role of inhibition in regulating UDSs, little is known about whether this role changes with maturation. This is surprising since both slow oscillations and UDSs exhibit significant age-dependent alterations. To elucidate the developmental impact of GABA(B) and GABA(A) receptors on UDS activity, we conducted simultaneous local field potentials and intracellular recordings ex vivo, in brain slices of young and adult male mice, using selective blockers, CGP55845 and a non-saturating concentration of gabazine, respectively. Blockade of both GABA(B) and GABA(A) signalling showed age-differentiated functions. CGP55845 caused an increase in Down state duration in young animals, but a decrease in adults. Gabazine evoked spike and wave discharges in both ages; however, while young networks became completely epileptic, adults maintained the ability to generate UDSs. Furthermore, voltage clamp recordings of miniature inhibitory postsynaptic currents revealed that gabazine selectively blocks phasic currents, particularly involving postsynaptic mechanisms. The latter exhibit clear maturational changes, suggesting a different subunit composition of GABA(A) receptors in young vs. adult animals. Indeed, subsequent local field potential recordings under diazepam (nanomolar or micromolar concentrations) revealed that mechanisms engaging the drug's classical binding site, mediated by alpha 1-subunit-containing GABA(A) receptors, make a bigger contribution to Up state initiation in young networks compared to adults. Taken together, these findings help clarify the mechanisms that underlie the maturation of cortical network activity and enhance our understanding regarding the emergence of neurodevelopmental disorders. Key points Slow oscillations, the EEG hallmark of non-REM sleep, and their cellular counterpart, Up and Down states (UDSs), are considered the default activity of the cerebral cortex and reflect the underlying neural connectivity. GABA(B)- and GABA(A)-receptor-mediated inhibition play a major role in regulating UDS activity. Although slow oscillations and UDSs exhibit significant alterations as a function of age, it is unknown how developmental changes in inhibition contribute to the developmental profile of this activity. In this study, we reveal for the first time age-dependent effects of GABA(B) and GABA(A) signalling on UDSs. We also document the differential subunit composition of postsynaptic GABA(A) receptors in young and adult animals, highlighting the alpha 1-subunit as a major component of the age-differentiated regulation of UDSs. These findings help clarify the mechanisms that underlie the maturation of cortical network activity, and enhance our understanding regarding the emergence of neurodevelopmental disorders.},
	keywords = {INHIBITION; MOUSE; Cerebral Cortex; Network dynamics; slow oscillations; mIPSCs; Up states},
	year = {2022},
	eissn = {1469-7793},
	pages = {2401-2427}
}

@article{MTMT:33646037,
	title = {Fast, high-throughput production of improved rabies viral vectors for specific, efficient and versatile transsynaptic retrograde labelling},
	url = {https://m2.mtmt.hu/api/publication/33646037},
	author = {Sumser, A. and Joesch, M. and Jonas, P. and Ben-Simon, Y.},
	doi = {10.7554/eLife.79848},
	journal-iso = {ELIFE},
	journal = {ELIFE},
	volume = {11},
	unique-id = {33646037},
	issn = {2050-084X},
	abstract = {To understand the function of neuronal circuits, it is crucial to disentangle the connectivity patterns within the network. However, most tools currently used to explore connectivity have low throughput, low selectivity, or limited accessibility. Here, we report the development of an improved packaging system for the production of the highly neurotropic RVdGenvA-CVS-N2c rabies viral vectors, yielding titers orders of magnitude higher with no background contamination, at a fraction of the production time, while preserving the efficiency of transsynaptic labeling. Along with the production pipeline, we developed suites of ‘starter’ AAV and bicistronic RVdG-CVS-N2c vectors, enabling retrograde labeling from a wide range of neuronal populations, tailored for diverse experimental requirements. We demonstrate the power and flexibility of the new system by uncovering hidden local and distal inhibitory connections in the mouse hippocampal formation and by imaging the functional properties of a cortical microcircuit across weeks. Our novel production pipeline provides a convenient approach to generate new rabies vectors, while our toolkit flexibly and efficiently expands the current capacity to label, manipulate and image the neuronal activity of interconnected neuronal circuits in vitro and in vivo. © Sumser et al.},
	keywords = {Animals; NEURONS; MICE; GENETICS; green fluorescent protein; hippocampus; ARTICLE; MOUSE; MICROSCOPY; animal; Cell Count; nonhuman; animal experiment; nerve cell; synaptic transmission; action potential; Genetic Vectors; image analysis; nerve cell plasticity; rabies; rabies; interneuron; Imaging; signal noise ratio; virus load; Electroporation; photostimulation; gene vector; synaptic potential; virus vector; functional connectivity; optogenetics; Rabies virus; Rabies virus; High throughput technology; neurotropic agent},
	year = {2022},
	eissn = {2050-084X}
}

@article{MTMT:31939787,
	title = {Comprehensive estimates of potential synaptic connections in local circuits of the rodent hippocampal formation by axonal-dendritic overlap},
	url = {https://m2.mtmt.hu/api/publication/31939787},
	author = {Tecuatl, C. and Wheeler, D.W. and Sutton, N. and Ascoli, G.A.},
	doi = {10.1523/JNEUROSCI.1193-20.2020},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {41},
	unique-id = {31939787},
	issn = {0270-6474},
	abstract = {A quantitative description of the hippocampal formation synaptic architecture is essential for understanding the neural mechanisms of episodic memory. Yet the existing knowledge of connectivity statistics between different neuron types in the rodent hippocampus only captures a mere 5% of this circuitry. We present a systematic pipeline to produce first-approximation estimates for most of the missing information. Leveraging the www.Hippocampome.org knowledge base, we derive local connection parameters between distinct pairs of morphologically identified neuron types based on their axonal-dendritic overlap within every layer and subregion of the hippocampal formation. Specifically, we adapt modern image analysis technology to determine the parcel-specific neurite lengths of every neuron type from representative morphologic reconstructions obtained from either sex. We then compute the average number of synapses per neuron pair using relevant anatomic volumes from the mouse brain atlas and ultrastructurally established interaction distances. Hence, we estimate connection probabilities and number of contacts for .1900 neuron type pairs, increasing the available quantitative assessments more than 11-fold. Connectivity statistics thus remain unknown for only a minority of potential synapses in the hippocampal formation, including those involving long-range (23%) or perisomatic (6%) connections and neuron types without morphologic tracings (7%). The described approach also yields approximate measurements of synaptic distances from the soma along the dendritic and axonal paths, which may affect signal attenuation and delay. Overall, this dataset fills a substantial gap in quantitatively describing hippocampal circuits and provides useful model specifications for biologically realistic neural network simulations, until further direct experimental data become available. © 2021 Society for Neuroscience. All rights reserved.},
	keywords = {Female; Male; hippocampus; ARTICLE; MOUSE; NETWORK; controlled study; nonhuman; animal experiment; Probability; quantitative analysis; brain region; learning; HIPPOCAMPAL CA3 REGION; ENTORHINAL CORTEX; ENTORHINAL CORTEX; ENTORHINAL CORTEX; CA1; dentate gyrus; dentate gyrus; dentate gyrus; synapse; simulation; DENDRITE; image analysis; interneuron; interneuron; rodent; episodic memory; artificial neural network; pipeline; knowledge base; neurite; hippocampal CA1 region; axon; subiculum; CA3},
	year = {2021},
	eissn = {1529-2401},
	pages = {1665-1683}
}

@article{MTMT:31941703,
	title = {Estrogen receptors alpha and beta mediate synaptic transmission in the pfc and hippocampus of mice},
	url = {https://m2.mtmt.hu/api/publication/31941703},
	author = {Zhang, M. and Weiland, H. and Schöfbänker, M. and Zhang, W.},
	doi = {10.3390/ijms22031485},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {22},
	unique-id = {31941703},
	issn = {1661-6596},
	abstract = {Distinct from ovarian estradiol, the steroid hormone 17ß-estradiol (E2) is produced in the brain and is involved in numerous functions, particularly acting as a neurosteroid. However, the physiological role of E2 and the mechanism of its effects are not well known. In hippocampal slices, 17ß-estradiol has been found to cause a modest increase in fast glutamatergic transmission; because some of these effects are rapid and acute, they might be mediated by membrane-associated receptors via nongenomic action. Moreover, activation of membrane estrogen receptors can rapidly modulate neuron function in a sex-specific manner. To further investigate the neurological role of E2, we examined the effect of E2, as an estrogen receptor (ER) agonist, on synaptic transmission in slices of the prefrontal cortex (PFC) and hippocampus in both male and female mice. Whole-cell recordings of spontaneous excitatory postsynaptic currents (sEPSC) in the PFC showed that E2 acts as a neuromodulator in glutamatergic transmission in the PFC in both sexes, but often in a cell-specific manner. The sEPSC amplitude and/or frequency responded to E2 in three ways, namely by significantly increasing, decreasing or having no response. Additional experiments using an agonist selective for ERß, diarylpropionitrile (DPN) showed that in males the sEPSC and spontaneous inhibitory postsynaptic currents sIPSC responses were similar to their E2 responses, but in females the estrogen receptor ß (ERß) agonist DPN did not influence excitatory transmission in the PFC. In contrast, in the hippocampus of both sexes E2 potentiated the gluatmatergic synaptic transmission in a subset of hippocampal cells. These data indicate that activation of E2 targeting probably a estrogen subtypes or different downstream signaling affect synaptic transmission in the brain PFC and hippocampus between males versus females mice. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.},
	keywords = {sex difference; synapse; ERα; ERSS; 17ß-Estrdiol},
	year = {2021},
	eissn = {1422-0067}
}

@article{MTMT:31190263,
	title = {Diversity of Axonal and Dendritic Contributions to Neuronal Output},
	url = {https://m2.mtmt.hu/api/publication/31190263},
	author = {Goaillard, J.-M. and Moubarak, E. and Tapia, M. and Tell, F.},
	doi = {10.3389/fncel.2019.00570},
	journal-iso = {FRONT CELL NEUROSCI},
	journal = {FRONTIERS IN CELLULAR NEUROSCIENCE},
	volume = {13},
	unique-id = {31190263},
	issn = {1662-5102},
	year = {2020},
	eissn = {1662-5102}
}

@article{MTMT:31411701,
	title = {Long-term potentiation of the nucleus reuniens and entorhinal cortex to CA1 distal dendritic synapses in mice},
	url = {https://m2.mtmt.hu/api/publication/31411701},
	author = {Vu, Thyna and Gugustea, Radu and Leung, L. Stan},
	doi = {10.1007/s00429-020-02095-6},
	journal-iso = {BRAIN STRUCT FUNC},
	journal = {BRAIN STRUCTURE & FUNCTION},
	volume = {225},
	unique-id = {31411701},
	issn = {1863-2653},
	abstract = {The present study investigated the short-term and long-term synaptic plasticity of excitatory synapses formed by the nucleus reuniens (RE) and entorhinal cortex (EC) on the distal apical dendrites of CA1 pyramidal cells. RE-CA1 synapses are implicated in memory involving the hippocampus and medial prefrontal cortex. Current source density (CSD) analysis was used to identify excitatory and inhibitory currents following stimulation of RE or medial perforant path (MPP) in urethane-anesthetized mice in vivo. At the distal apical dendrites, RE evoked an initial excitatory sink followed by inhibitory sources at short (similar to 30 ms) and long (150-200 ms) latencies, and often showing gamma (25-40 Hz) oscillations. Both RE-evoked and spontaneous gamma-frequency local field potentials displayed the same CSD depth profile. Paired-pulse facilitation (PPF) of the distal excitatory sink at 20-200 ms interpulse intervals was observed following RE stimulation, generally higher than that following MPP stimulation. Theta-frequency burst stimulation (TBS) of RE induced input-specific long-term potentiation (LTP) at the distal dendritic CA1 synapses, accompanied by reduction of PPF. After TBS of the MPP, the MPP-CA1 distal dendritic synapse could manifest LTP or long-term depression, but the non-tetanized RE-CA1 synapse was typically potentiated. Heterosynaptic potentiation of the RE to CA1 distal synapses may occur after repeated activity of EC afferents, or spread of MPP stimulus currents to coursing RE afferents. The results indicate a propensity of RE-CA1 distal excitatory synapses to show PPF, LTP and gamma oscillations, all of which may participate in memory processing by RE and EC.},
	keywords = {LONG-TERM POTENTIATION; Nucleus reuniens; GAMMA OSCILLATIONS; Current source density; paired-pulse facilitation; temporoammonic pathway},
	year = {2020},
	eissn = {1863-2661},
	pages = {1817-1838},
	orcid-numbers = {Leung, L. Stan/0000-0001-8887-4869}
}

@article{MTMT:30894033,
	title = {Steady-state activation and modulation of the synaptic-type alpha 1 beta 2 gamma 2L GABA(A) receptor by combinations of physiological and clinical ligands},
	url = {https://m2.mtmt.hu/api/publication/30894033},
	author = {German, Allison L. and Pierce, Spencer R. and Senneff, Thomas C. and Burbridge, Ariel B. and Steinbach, Joe Henry and Akk, Gustav},
	doi = {10.14814/phy2.14230},
	journal-iso = {PHYSIOL REPORTS},
	journal = {PHYSIOLOGICAL REPORTS},
	volume = {7},
	unique-id = {30894033},
	abstract = {The synaptic alpha 1 beta 2 gamma 2 GABA(A) receptor is activated phasically by presynaptically released GABA. The receptor is considered to be inactive between synaptic events when exposed to ambient GABA because of its low resting affinity to the transmitter. We tested the hypothesis that a combination of physiological and/or clinical positive allosteric modulators of the GABA(A) receptor with ambient GABA generates measurable steady-state activity. Recombinant alpha 1 beta 2 gamma 2L GABA(A) receptors were expressed in Xenopus oocytes and activated by combinations of low concentrations of orthosteric (GABA, taurine) and allosteric (the steroid allopregnanolone, the anesthetic propofol) agonists, in the absence and presence of the inhibitory steroid pregnenolone sulfate. Steady-state activity was analyzed using the three-state cyclic Resting-Active-Desensitized model. We estimate that the steady-state open probability of the synaptic alpha 1 beta 2 gamma 2L GABA(A) receptor in the presence of ambient GABA (1 mu mol/L), taurine (10 mu mol/L), and physiological levels of allopregnanolone (0.01 mu mol/L) and pregnenolone sulfate (0.1 mu mol/L) is 0.008. Coapplication of a clinical concentration of propofol (1 mu mol/L) increases the steady-state open probability to 0.03. Comparison of total charge transfer for phasic and tonic activity indicates that steady-state activity can contribute strongly (similar to 20 to >99%) to integrated activity from the synaptic GABA(A) receptor.},
	keywords = {Electrophysiology; ANESTHETICS; GABA(A) RECEPTORS; Neurosteroids},
	year = {2019},
	eissn = {2051-817X}
}

@article{MTMT:31318277,
	title = {Intravenous lipid emulsion modifies synaptic transmission in hippocampal CA1 pyramidal neurons after bupivacaine-induced central nervous system toxicity},
	url = {https://m2.mtmt.hu/api/publication/31318277},
	author = {Nie, H. and Bai, Z. and Li, Z. and Yan, L. and Chen, X.-X.},
	doi = {10.1111/jnc.14924},
	journal-iso = {J NEUROCHEM},
	journal = {JOURNAL OF NEUROCHEMISTRY},
	volume = {154},
	unique-id = {31318277},
	issn = {0022-3042},
	keywords = {synaptic transmission; bupivacaine; local anesthetic systemic toxicity; central nervous system toxicity; hippocampal CA1 pyramidal neurons; lipid emulsion therapy},
	year = {2019},
	eissn = {1471-4159},
	pages = {144-157}
}

@article{MTMT:27658357,
	title = {Morphological diversity and connectivity of hippocampal interneurons},
	url = {https://m2.mtmt.hu/api/publication/27658357},
	author = {Booker, SA and Vida, I},
	doi = {10.1007/s00441-018-2882-2},
	journal-iso = {CELL TISSUE RES},
	journal = {CELL AND TISSUE RESEARCH},
	volume = {373},
	unique-id = {27658357},
	issn = {0302-766X},
	abstract = {The mammalian forebrain is constructed from ensembles of neurons that form local microcircuits giving rise to the exquisite cognitive tasks the mammalian brain can perform. Hippocampal neuronal circuits comprise populations of relatively homogenous excitatory neurons, principal cells and exceedingly heterogeneous inhibitory neurons, the interneurons. Interneurons release GABA from their axon terminals and are capable of controlling excitability in every cellular compartment of principal cells and interneurons alike; thus, they provide a brake on excess activity, control the timing of neuronal discharge and provide modulation of synaptic transmission. The dendritic and axonal morphology of interneurons, as well as their afferent and efferent connections within hippocampal circuits, is central to their ability to differentially control excitability, in a cell-type- and compartment-specific manner. This review aims to provide an up-to-date compendium of described hippocampal interneuron subtypes, with respect to their morphology, connectivity, neurochemistry and physiology, a full understanding of which will in time help to explain the rich diversity of neuronal function. © 2018, The Author(s).},
	keywords = {hippocampus; review; human; Cortical Synchronization; MORPHOLOGY; priority journal; CHOLECYSTOKININ; GABA; Connectivity; HIPPOCAMPAL CA3 REGION; nerve cell; synaptic transmission; dentate gyrus; nerve excitability; GABAergic system; interneuron; perforant nerve tract; Dendritic cell; parvalbumin; glia cell; nerve cell network; stratum radiatum; stratum oriens; functional connectivity; hippocampal CA1 region; synaptic inhibition; stratum pyramidale; connectome; axon; hippocampal CA2 region; hippocampal mossy fiber; Basket cell; bistratified cell; ivy cell; medium spiny neuron; Schaffer collateral pathway; stratum lacunosum moleculare},
	year = {2018},
	eissn = {1432-0878},
	pages = {619-641}
}

@article{MTMT:27660903,
	title = {Name-calling in the hippocampus (and beyond): coming to terms with neuron types and properties},
	url = {https://m2.mtmt.hu/api/publication/27660903},
	author = {Hamilton, DJ and Wheeler, DW and White, CM and Rees, CL and Komendantov, AO and Bergamino, M and Ascoli, GA},
	doi = {10.1007/s40708-016-0053-3},
	journal-iso = {BRAIN INFORMATICS},
	journal = {BRAIN INFORMATICS},
	volume = {4},
	unique-id = {27660903},
	issn = {2198-4018},
	year = {2017}
}

@article{MTMT:27352373,
	title = {HIPPOCAMPAL GABAERGIC INHIBITORY INTERNEURONS},
	url = {https://m2.mtmt.hu/api/publication/27352373},
	author = {Pelkey, Kenneth A and Chittajallu, Ramesh and Craig, Michael T and Tricoire, Ludovic and Wester, Jason C and McBain, Chris J},
	doi = {10.1152/physrev.00007.2017},
	journal-iso = {PHYSIOL REV},
	journal = {PHYSIOLOGICAL REVIEWS},
	volume = {97},
	unique-id = {27352373},
	issn = {0031-9333},
	keywords = {Animals; Humans; metabolism; GAMMA-AMINOBUTYRIC ACID; hippocampus; hippocampus; hippocampus; ARTICLE; PATHOPHYSIOLOGY; human; animal; OPIATE RECEPTOR; priority journal; CHOLECYSTOKININ; nonhuman; pathology; serotonin receptor; Neural Inhibition; synaptic transmission; synaptic transmission; central nervous system disease; embryo; Nerve Net; nerve cell plasticity; GABAergic system; 4 aminobutyric acid; glutamate receptor; interneuron; interneuron; Central Nervous System Diseases; GABAERGIC NEURONS; cholinergic receptor; nerve cell inhibition; Receptors, GABA; 4 aminobutyric acid receptor; 4 aminobutyric acid receptor; nerve cell network; endocannabinoid; dopamine receptor; embryo development; connectome; oxytocin receptor; presynaptic inhibition; interneurons},
	year = {2017},
	eissn = {1522-1210},
	pages = {1619-1747}
}

@article{MTMT:3255790,
	title = {Extended Interneuronal Network of the Dentate Gyrus},
	url = {https://m2.mtmt.hu/api/publication/3255790},
	author = {Szabo, GG and Du, X and Oijala, M and Varga, Csaba and Parent, JM and Soltesz, I},
	doi = {10.1016/j.celrep.2017.07.042},
	journal-iso = {CELL REP},
	journal = {CELL REPORTS},
	volume = {20},
	unique-id = {3255790},
	issn = {2211-1247},
	year = {2017},
	eissn = {2211-1247},
	pages = {1262-1268}
}

@article{MTMT:26937496,
	title = {Functional compatibility between Purkinje cell axon branches and their target neurons in the cerebellum},
	url = {https://m2.mtmt.hu/api/publication/26937496},
	author = {Yang, Zhilai and Chen, Na and Ge, Rongjing and Qian, Hao and Wang, Jin-Hui},
	doi = {10.18632/oncotarget.19770},
	journal-iso = {ONCOTARGET},
	journal = {ONCOTARGET},
	volume = {8},
	unique-id = {26937496},
	year = {2017},
	eissn = {1949-2553},
	pages = {72424-72437}
}

@article{MTMT:27029396,
	title = {Interneuronal mechanisms of hippocampal theta oscillations in a full-scale model of the rodent CA1 circuit},
	url = {https://m2.mtmt.hu/api/publication/27029396},
	author = {Bezaire, Marianne J and Raikov, Ivan and Burk, Kelly and Vyas, Dhrumil and Soltesz, Ivan},
	doi = {10.7554/eLife.18566},
	journal-iso = {ELIFE},
	journal = {ELIFE},
	volume = {5},
	unique-id = {27029396},
	issn = {2050-084X},
	year = {2016},
	eissn = {2050-084X},
	orcid-numbers = {Raikov, Ivan/0000-0002-8224-8549}
}

@article{MTMT:3078169,
	title = {Properties and dynamics of inhibitory synaptic communication within the CA3 microcircuits of pyramidal cells and interneurons expressing parvalbumin or cholecystokinin},
	url = {https://m2.mtmt.hu/api/publication/3078169},
	author = {Kohus, Zsolt and Káli, Szabolcs and Rovira Esteban, Laura and Schlingloff, Dániel and Papp, Orsolya and Freund, Tamás and Hájos, Norbert and Gulyás, Attila},
	doi = {10.1113/JP272231},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {594},
	unique-id = {3078169},
	issn = {0022-3751},
	abstract = {Different hippocampal activity patterns are determined primarily by the interaction of excitatory cells and different types of interneurons. To understand the mechanisms underlying the generation of different network dynamics the properties of synaptic transmission need to be uncovered. Perisomatic inhibition has been shown to be critical for the generation of sharp wave-ripples, gamma oscillations as well as pathological epileptic activities. Therefore, we decided to quantitatively and systematically characterize the temporal properties of the synaptic transmission between perisomatic inhibitory neurons and pyramidal cells in the CA3 area of mouse hippocampal slices, using action potential patterns recorded during physiological and pathological network states. PV+ and CCK+ interneurons had distinct intrinsic physiological features. Interneurons of the same type formed reciprocally connected subnetworks, while the connectivity between interneuron classes was sparse. The characteristics of unitary interactions depended on the identity of both synaptic partners, while the short-term plasticity of synaptic transmission depended mainly on the presynaptic cell type. PV+ interneurons showed frequency-dependent depression, while more complex dynamics characterized the output of CCK+ interneurons. We quantitatively captured the dynamics of transmission at these different types of connection with simple mathematical models, and described in detail the response to physiological and pathological discharge patterns. Our data suggest that the temporal propeties of PV+ interneuron transmission may contribute to sharp wave-ripple generation. These findings support the view that intrinsic and synaptic features of PV+ cells make them ideally suited for the generation of physiological network oscillations, while CCK+ cells implement more subtle, graded control in the hippocampus. This article is protected by copyright. All rights reserved.},
	year = {2016},
	eissn = {1469-7793},
	pages = {3745-3774},
	orcid-numbers = {Kohus, Zsolt/0000-0002-2153-615X; Gulyás, Attila/0000-0003-4961-636X}
}

@article{MTMT:26832257,
	title = {A Unified Dynamic Model for Learning, Replay, and Sharp-Wave/Ripples},
	url = {https://m2.mtmt.hu/api/publication/26832257},
	author = {Jahnke, Sven and Timme, Marc and Memmesheimer, Raoul-Martin},
	doi = {10.1523/JNEUROSCI.3977-14.2015},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {35},
	unique-id = {26832257},
	issn = {0270-6474},
	year = {2015},
	eissn = {1529-2401},
	pages = {16236-16258}
}

@article{MTMT:25863140,
	title = {Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome},
	url = {https://m2.mtmt.hu/api/publication/25863140},
	author = {Rubinstein, Moran and Westenbroek, Ruth E and Yu, Frank H and Jones, Christina J and Scheuer, Todd and Catterall, William A},
	doi = {10.1016/j.nbd.2014.09.017},
	journal-iso = {NEUROBIOL DIS},
	journal = {NEUROBIOLOGY OF DISEASE},
	volume = {73},
	unique-id = {25863140},
	issn = {0969-9961},
	year = {2015},
	eissn = {1095-953X},
	pages = {106-117}
}

@article{MTMT:25712723,
	title = {Multiple types of GABAA responses identified from zebrafish Mauthner cells},
	url = {https://m2.mtmt.hu/api/publication/25712723},
	author = {Roy, Birbickram and Ali, Declan W},
	doi = {10.1097/WNR.0000000000000258},
	journal-iso = {NEUROREPORT},
	journal = {NEUROREPORT},
	volume = {25},
	unique-id = {25712723},
	issn = {0959-4965},
	year = {2014},
	eissn = {1473-558X},
	pages = {1232-1236},
	orcid-numbers = {Roy, Birbickram/0000-0002-5702-9256}
}

@article{MTMT:25863192,
	title = {Dendritic Inhibition Provided by Interneuron-Specific Cells Controls the Firing Rate and Timing of the Hippocampal Feedback Inhibitory Circuitry},
	url = {https://m2.mtmt.hu/api/publication/25863192},
	author = {Tyan, Leonid and Chamberland, Simon and Magnin, Elise and Camire, Olivier and Francavilla, Ruggiero and David, Linda Suzanne and Deisseroth, Karl and Topolnik, Lisa},
	doi = {10.1523/JNEUROSCI.3813-13.2014},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {34},
	unique-id = {25863192},
	issn = {0270-6474},
	year = {2014},
	eissn = {1529-2401},
	pages = {4534-4547}
}

@article{MTMT:31269855,
	title = {Modulation of hippocampal rhythms by subthreshold electric fields and network topology},
	url = {https://m2.mtmt.hu/api/publication/31269855},
	author = {Berzhanskaya, J and Chernyy, N and Gluckman, BJ and Schiff, SJ and Ascoli, GA},
	doi = {10.1007/s10827-012-0426-4},
	journal-iso = {J COMPUT NEUROSCI},
	journal = {JOURNAL OF COMPUTATIONAL NEUROSCIENCE},
	volume = {34},
	unique-id = {31269855},
	issn = {0929-5313},
	year = {2013},
	eissn = {1573-6873},
	pages = {369-389}
}

@article{MTMT:2941489,
	title = {Quantitative assessment of CA1 local circuits: Knowledge base for interneuron-pyramidal cell connectivity},
	url = {https://m2.mtmt.hu/api/publication/2941489},
	author = {Bezaire, MJ and Soltesz, Ivan},
	doi = {10.1002/hipo.22141},
	journal-iso = {HIPPOCAMPUS},
	journal = {HIPPOCAMPUS},
	volume = {23},
	unique-id = {2941489},
	issn = {1050-9631},
	abstract = {In this work, through a detailed literature review, data-mining, and extensive calculations, we provide a current, quantitative estimate of the cellular and synaptic constituents of the CA1 region of the rat hippocampus. Beyond estimating the cell numbers of GABAergic interneuron types, we calculate their convergence onto CA1 pyramidal cells and compare it with the known input synapses on CA1 pyramidal cells. The convergence calculation and comparison are also made for excitatory inputs to CA1 pyramidal cells. In addition, we provide a summary of the excitatory and inhibitory convergence onto interneurons. The quantitative knowledge base assembled and synthesized here forms the basis for data-driven, large-scale computational modeling efforts. Additionally, this work highlights specific instances where the available data are incomplete, which should inspire targeted experimental projects toward a more complete quantification of the CA1 neurons and their connectivity. (c) 2013 Wiley Periodicals, Inc.},
	keywords = {TEMPORAL-LOBE EPILEPSY; SYNAPSES; MEDIAL SEPTUM; dentate gyrus; convergence; HIPPOCAMPUS IN-VITRO; GABAERGIC NEURONS; Divergence; BASKET CELLS; TOTAL NUMBER; ADULT-RAT HIPPOCAMPUS; DUAL INTRACELLULAR-RECORDINGS; POLYPEPTIDE-IMMUNOREACTIVE INTERNEURONS; boutons; big data},
	year = {2013},
	eissn = {1098-1063},
	pages = {751-785}
}

@article{MTMT:2369864,
	title = {Feedforward Inhibition Underlies the Propagation of Cholinergically Induced Gamma Oscillations from Hippocampal CA3 to CA1.},
	url = {https://m2.mtmt.hu/api/publication/2369864},
	author = {Zemankovics, Rita and Veres, Judit and Oren, I and Hájos, Norbert},
	doi = {10.1523/JNEUROSCI.3680-12.2013},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {33},
	unique-id = {2369864},
	issn = {0270-6474},
	abstract = {Gamma frequency (30-80 Hz) oscillations are implicated in memory processing. Such rhythmic activity can be generated intrinsically in the CA3 region of the hippocampus from where it can propagate to the CA1 area. To uncover the synaptic mechanisms underlying the intrahippocampal spread of gamma oscillations, we recorded local field potentials, as well as action potentials and synaptic currents in anatomically identified CA1 and CA3 neurons during carbachol-induced gamma oscillations in mouse hippocampal slices. The firing of the vast majority of CA1 neurons and all CA3 neurons was phase-coupled to the oscillations recorded in the stratum pyramidale of the CA1 region. The predominant synaptic input to CA1 interneurons was excitatory, and their discharge followed the firing of CA3 pyramidal cells at a latency indicative of monosynaptic connections. Correlation analysis of the input-output characteristics of the neurons and local pharmacological block of inhibition both agree with a model in which glutamatergic CA3 input controls the firing of CA1 interneurons, with local pyramidal cell activity having a minimal role. The firing of phase-coupled CA1 pyramidal cells was controlled principally by their inhibitory inputs, which dominated over excitation. Our results indicate that the synchronous firing of CA3 pyramidal cells rhythmically recruits CA1 interneurons and that this feedforward inhibition generates the oscillatory activity in CA1. These findings identify distinct synaptic mechanisms underlying the generation of gamma frequency oscillations in neighboring hippocampal subregions.},
	year = {2013},
	eissn = {1529-2401},
	pages = {12337-12351}
}

@article{MTMT:25002714,
	title = {Inhibitory control of hippocampal inhibitory neurons},
	url = {https://m2.mtmt.hu/api/publication/25002714},
	author = {Chamberland, Simon and Topolnik, Lisa},
	doi = {10.3389/fnins.2012.00165},
	journal-iso = {FRONT NEUROSCI-SWITZ},
	journal = {FRONTIERS IN NEUROSCIENCE},
	volume = {6},
	unique-id = {25002714},
	issn = {1662-4548},
	year = {2012},
	eissn = {1662-453X}
}

@article{MTMT:25003698,
	title = {GABA(A,slow): causes and consequences},
	url = {https://m2.mtmt.hu/api/publication/25003698},
	author = {Capogna, Marco and Pearce, Robert A},
	doi = {10.1016/j.tins.2010.10.005},
	journal-iso = {TRENDS NEUROSCI},
	journal = {TRENDS IN NEUROSCIENCES},
	volume = {34},
	unique-id = {25003698},
	issn = {0166-2236},
	year = {2011},
	eissn = {1878-108X},
	pages = {101-112}
}

@article{MTMT:25003696,
	title = {Neurogliaform cells and other interneurons of stratum lacunosum-moleculare gate entorhinal-hippocampal dialogue},
	url = {https://m2.mtmt.hu/api/publication/25003696},
	author = {Capogna, Marco},
	doi = {10.1113/jphysiol.2010.201004},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {589},
	unique-id = {25003696},
	issn = {0022-3751},
	year = {2011},
	eissn = {1469-7793},
	pages = {1875-1883}
}

@article{MTMT:1433117,
	title = {Cholinergic modulation amplifies the intrinsic oscillatory properties of CA1 hippocampal cholecystokinin-positive interneurons},
	url = {https://m2.mtmt.hu/api/publication/1433117},
	author = {Cea-Del Rio, CA and Lawrence, JJ and Erdélyi, Ferenc and Szabó, Gábor and McBain, CJ},
	doi = {10.1113/jphysiol.2010.199422},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {589},
	unique-id = {1433117},
	issn = {0022-3751},
	abstract = {Non-technical summary In the mammalian hippocampus, the neurotransmitter acetylcholine (ACh) promotes learning and memory storage. During sensory processing and learning, large ACh-dependent electrical oscillatory events are observed, which involve the synchronization of both inhibitory and excitatory neural circuits. While the actions of ACh are known on excitatory hippocampal circuits, its actions on specific inhibitory circuits are poorly understood. We show that two types of cholecystokinin-positive local circuit inhibitory interneuron, the so-called 'basket cells' and 'Schaffer collateral-associated' cells, which innervate separately the cell body and dendritic regions of principal cells, are modulated similarly by cholinergic receptor activation. In both cell types activation of their muscarinic receptors triggers a general increase of excitability and intrinsic oscillatory activity, and a more efficient engagement to slow network oscillations. Knowledge of how cholinergic neuromodulation acts on neurochemically identical but morphologically distinct inhibitory interneurons will allow us to understand the role played by this important neuromodulator during hippocampal-dependent tasks in vivo.},
	year = {2011},
	eissn = {1469-7793},
	pages = {609-627}
}

@article{MTMT:21901276,
	title = {Glutamatergic input is selectively increased in dorsal raphe subfield 5-HT neurons: role of morphology, topography and selective innervation},
	url = {https://m2.mtmt.hu/api/publication/21901276},
	author = {Crawford, LK and Craige, CP and Beck, SG},
	doi = {10.1111/j.1460-9568.2011.07882.x},
	journal-iso = {EUR J NEUROSCI},
	journal = {EUROPEAN JOURNAL OF NEUROSCIENCE},
	volume = {34},
	unique-id = {21901276},
	issn = {0953-816X},
	year = {2011},
	eissn = {1460-9568},
	pages = {1794-1806}
}

@article{MTMT:26787890,
	title = {Postnatal development of dendrodendritic inhibition in the mammalian olfactory bulb},
	url = {https://m2.mtmt.hu/api/publication/26787890},
	author = {Dietz, SB and Markopoulos, F and Murthy, VN},
	doi = {10.3389/fncel.2011.00010},
	journal-iso = {FRONT CELL NEUROSCI},
	journal = {FRONTIERS IN CELLULAR NEUROSCIENCE},
	volume = {5},
	unique-id = {26787890},
	issn = {1662-5102},
	year = {2011},
	eissn = {1662-5102}
}

@article{MTMT:1424451,
	title = {Roller Coaster Scanning reveals spontaneous triggering of dendritic spikes in CA1 interneurons},
	url = {https://m2.mtmt.hu/api/publication/1424451},
	author = {Katona, Gergely and Kaszás, Attila and Turi, Gergely and Hájos, Norbert and Tamás, Gábor and Vizi, E. Szilveszter and Rózsa J., Balázs},
	doi = {10.1073/pnas.1009270108},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {108},
	unique-id = {1424451},
	issn = {0027-8424},
	abstract = {Inhibitory interneurons are considered to be the controlling units of neural networks, despite their sparse number and unique morphological characteristics compared with excitatory pyramidal cells. Although pyramidal cell dendrites have been shown to display local regenerative events-dendritic spikes (dSpikes)-evoked by artificially patterned stimulation of synaptic inputs, no such studies exist for interneurons or for spontaneous events. In addition, imaging techniques have yet to attain the required spatial and temporal resolution for the detection of spontaneously occurring events that trigger dSpikes. Here we describe a high-resolution 3D two-photon laser scanning method (Roller Coaster Scanning) capable of imaging long dendritic segments resolving individual spines and inputs with a temporal resolution of a few milliseconds. By using this technique, we found that local, NMDA receptor-dependent dSpikes can be observed in hippocampal CA1 stratum radiatum interneurons during spontaneous network activities in vitro. These NMDA spikes appear when approximately 10 spatially clustered inputs arrive synchronously and trigger supralinear integration in dynamic interaction zones. In contrast to the one-to-one relationship between computational subunits and dendritic branches described in pyramidal cells, here we show that interneurons have relatively small ( approximately 14 mum) sliding interaction zones. Our data suggest a unique principle as to how interneurons integrate synaptic information by local dSpikes.},
	year = {2011},
	eissn = {1091-6490},
	pages = {2148-2153},
	orcid-numbers = {Katona, Gergely/0000-0002-4173-0355; Tamás, Gábor/0000-0002-7905-6001; Vizi, E. Szilveszter/0000-0002-9557-4597}
}

@article{MTMT:26177688,
	title = {GenNet: A platform for hybrid network experiments},
	url = {https://m2.mtmt.hu/api/publication/26177688},
	author = {Kispersky, TJ and Economo, MN and Randeria, P and White, JA},
	doi = {10.3389/fninf.2011.00011},
	journal-iso = {FRONT NEUROINFORM},
	journal = {FRONTIERS IN NEUROINFORMATICS},
	volume = {5},
	unique-id = {26177688},
	year = {2011},
	eissn = {1662-5196}
}

@article{MTMT:27029740,
	title = {Age-dependent remodelling of inhibitory synapses onto hippocampal CA1 oriens-lacunosum moleculare interneurons},
	url = {https://m2.mtmt.hu/api/publication/27029740},
	author = {Salesse, Charleen and Mueller, Christopher Lacharite and Chamberland, Simon and Topolnik, Lisa},
	doi = {10.1113/jphysiol.2011.215244},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {589},
	unique-id = {27029740},
	issn = {0022-3751},
	year = {2011},
	eissn = {1469-7793},
	pages = {4885-4901}
}

@article{MTMT:27197322,
	title = {Dynamic modulation of short-term synaptic plasticity in the auditory cortex: The role of norepinephrine},
	url = {https://m2.mtmt.hu/api/publication/27197322},
	author = {Salgado, H and Garcia-Oscos, F and Dinh, L and Atzori, M},
	doi = {10.1016/j.heares.2010.08.014},
	journal-iso = {HEARING RES},
	journal = {HEARING RESEARCH},
	volume = {271},
	unique-id = {27197322},
	issn = {0378-5955},
	year = {2011},
	eissn = {1878-5891},
	pages = {26-36}
}

@article{MTMT:21901275,
	title = {Layer-Specific Noradrenergic Modulation of Inhibition in Cortical Layer II/III},
	url = {https://m2.mtmt.hu/api/publication/21901275},
	author = {Salgado, H and Garcia-Oscos, F and Patel, A and Martinolich, L and Nichols, JA and Dinh, L and Roychowdhury, S and Tseng, KY and Atzori, M},
	doi = {10.1093/cercor/bhq081},
	journal-iso = {CEREB CORTEX},
	journal = {CEREBRAL CORTEX},
	volume = {21},
	unique-id = {21901275},
	issn = {1047-3211},
	year = {2011},
	eissn = {1460-2199},
	pages = {212-221}
}

@article{MTMT:27029735,
	title = {A Blueprint for the Spatiotemporal Origins of Mouse Hippocampal Interneuron Diversity},
	url = {https://m2.mtmt.hu/api/publication/27029735},
	author = {Tricoire, Ludovic and Pelkey, Kenneth A and Erkkila, Brian E and Jeffries, Brian W and Yuan, Xiaoqing and McBain, Chris J},
	doi = {10.1523/JNEUROSCI.0323-11.2011},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {31},
	unique-id = {27029735},
	issn = {0270-6474},
	year = {2011},
	eissn = {1529-2401},
	pages = {10948-10970}
}

@article{MTMT:27029724,
	title = {Synapse-specific inhibitory control of hippocampal feedback inhibitory circuit},
	url = {https://m2.mtmt.hu/api/publication/27029724},
	author = {Chamberland, Simon and Salesse, Charleen and Topolnik, Dimitry and Topolnik, Lisa},
	doi = {10.3389/fncel.2010.00130},
	journal-iso = {FRONT CELL NEUROSCI},
	journal = {FRONTIERS IN CELLULAR NEUROSCIENCE},
	volume = {4},
	unique-id = {27029724},
	issn = {1662-5102},
	year = {2010},
	eissn = {1662-5102}
}

@article{MTMT:26269554,
	title = {Slow GABA Transient and Receptor Desensitization Shape Synaptic Responses Evoked by Hippocampal Neurogliaform Cells},
	url = {https://m2.mtmt.hu/api/publication/26269554},
	author = {Karayannis, Theofanis and Elfant, David and Huerta-Ocampo, Icnelia and Teki, Sundeep and Scott, Ricardo S and Rusakov, Dmitri A and Jones, Mathew V and Capogna, Marco},
	doi = {10.1523/JNEUROSCI.5883-09.2010},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {30},
	unique-id = {26269554},
	issn = {0270-6474},
	year = {2010},
	eissn = {1529-2401},
	pages = {9898-9909}
}

@article{MTMT:2833483,
	title = {Distinct endocannabinoid control of GABA release at perisomatic and dendritic synapses in the hippocampus},
	url = {https://m2.mtmt.hu/api/publication/2833483},
	author = {Lee, S-H and Földy, Csaba and Soltesz, Ivan},
	doi = {10.1523/JNEUROSCI.6238-09.2010},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {30},
	unique-id = {2833483},
	issn = {0270-6474},
	abstract = {Endocannabinoid-mediated retrograde synaptic signaling is a key regulator of GABA release at synapses formed on the perisomatic region of pyramidal cells by basket cells that coexpress the cannabinoid type 1 receptor (CB1R) and cholecystokinin (CCK). However, CB1R and CCK-positive GABAergic terminals are present on pyramidal cell dendrites as well, but the principles of endocannabinoid control of GABA release in dendrites are not understood. We performed paired recordings from CCK-positive perisomatically (basket cells) or dendritically projecting (Schaffer collateral-associated cells) interneurons and postsynaptic CA1 pyramidal cells to determine the properties of endocannabinoid signaling at GABAergic synapses along the somato-dendritic axis. Although several key elements of the currently known molecular machinery for endocannabinoid synthesis are thought be primarily localized in dendrites, our results revealed that the depolarization-induced suppression of inhibition, the endocannabinoid-mediated tonic inhibition of GABA release, and the metabotropic glutamate receptor activation-induced, CB1R-mediated depression of GABA release were all significantly less effective at dendritic compared with perisomatic synapses. In addition, low concentration of exogenous CB1 receptor agonist inhibited GABA release to a lesser extent at dendritic compared with perisomatic synapses, indicating that presynaptic differences are partly responsible for the differential control of GABA release by endocannabinoids in dendrites. Together, these data demonstrate a novel domain-specific regulation of GABA release by endocannabinoid signaling in the hippocampus. Copyright © 2010 the authors.},
	keywords = {Animals; Male; GAMMA-AMINOBUTYRIC ACID; immunohistochemistry; hippocampus; RATS; ARTICLE; DEPOLARIZATION; signal transduction; Rats, Sprague-Dawley; Electrophysiology; priority journal; CHOLECYSTOKININ; nonhuman; animal tissue; animal cell; SYNAPSES; PYRAMIDAL CELLS; synaptic transmission; postsynaptic membrane; cellular distribution; DENDRITE; Organ Culture Techniques; Patch-Clamp Techniques; Endocannabinoids; CA1 Region, Hippocampal; 4 aminobutyric acid; pyramidal nerve cell; interneuron; Receptor, Cannabinoid, CB1; cannabinoid 1 receptor; Dendrites; somatic cell; GABAergic transmission; 4 aminobutyric acid release; Receptors, Metabotropic Glutamate; metabotropic receptor; endocannabinoid; rat; interneurons},
	year = {2010},
	eissn = {1529-2401},
	pages = {7993-8000}
}

@article{MTMT:1335858,
	title = {Altered organization of GABAA receptor mRNA expression in the depressed suicide brain},
	url = {https://m2.mtmt.hu/api/publication/1335858},
	author = {Poulter, MO and Du, L and Zhurov, V and Palkovits, Miklós and Faludi, Gábor and Merali, Z and Anisman, H},
	doi = {10.3389/neuro.02.003.2010},
	journal-iso = {FRONT MOL NEUROSCI},
	journal = {FRONTIERS IN MOLECULAR NEUROSCIENCE},
	volume = {3},
	unique-id = {1335858},
	issn = {1662-5099},
	year = {2010},
	eissn = {1662-5099},
	orcid-numbers = {Palkovits, Miklós/0000-0003-0578-0387; Faludi, Gábor/0000-0002-1117-0510}
}

@article{MTMT:21316153,
	title = {PLASTICITY OF THE GABA(A) RECEPTOR SUBUNIT CASSETTE IN RESPONSE TO STRESSORS IN REACTIVE VERSUS RESILIENT MICE},
	url = {https://m2.mtmt.hu/api/publication/21316153},
	author = {Poulter, MO and Du, L and Zhurov, V and Merali, Z and Anisman, H},
	doi = {10.1016/j.neuroscience.2009.11.028},
	journal-iso = {NEUROSCIENCE},
	journal = {NEUROSCIENCE},
	volume = {165},
	unique-id = {21316153},
	issn = {0306-4522},
	year = {2010},
	eissn = {1873-7544},
	pages = {1039-1051}
}

@article{MTMT:27029706,
	title = {GABAergic interneurons targeting dendrites of pyramidal cells in the CA1 area of the hippocampus},
	url = {https://m2.mtmt.hu/api/publication/27029706},
	author = {Klausberger, Thomas},
	doi = {10.1111/j.1460-9568.2009.06913.x},
	journal-iso = {EUR J NEUROSCI},
	journal = {EUROPEAN JOURNAL OF NEUROSCIENCE},
	volume = {30},
	unique-id = {27029706},
	issn = {0953-816X},
	year = {2009},
	eissn = {1460-9568},
	pages = {947-957}
}

@article{MTMT:2086363,
	title = {Neuronal diversity and temporal dynamics: the unity of hippocampal circuit operations.},
	url = {https://m2.mtmt.hu/api/publication/2086363},
	author = {Klausberger, T and Somogyi, Péter Pál},
	doi = {10.1126/science.1149381},
	journal-iso = {SCIENCE},
	journal = {SCIENCE},
	volume = {321},
	unique-id = {2086363},
	issn = {0036-8075},
	abstract = {In the cerebral cortex, diverse types of neurons form intricate 
		circuits and cooperate in time for the processing and storage of 
		information. Recent advances reveal a spatiotemporal division 
		of labor in cortical circuits, as exemplified in the CA1 
		hippocampal area. In particular, distinct GABAergic (gamma-
		aminobutyric acid-releasing) cell types subdivide the surface of 
		pyramidal cells and act in discrete time windows, either on the 
		same or on different subcellular compartments. They also 
		interact with glutamatergic pyramidal cell inputs in a domain-
		specific manner and support synaptic temporal dynamics, network 
		oscillations, selection of cell assemblies, and the 
		implementation of brain states. The spatiotemporal 
		specializations in cortical circuits reveal that cellular 
		diversity and temporal dynamics coemerged during evolution, 
		providing a basis for cognitive behavior.},
	keywords = {Animals; Humans; Neurons/*physiology; Nerve Net/*physiology; Hippocampus/cytology/*physiology; Pyramidal Cells/*physiology; Synapses/physiology; cognition; Neural Pathways/physiology; Axons/physiology; gamma-Aminobutyric Acid/metabolism; Dendrites/physiology; Interneurons/*physiology; Biological Evolution},
	year = {2008},
	eissn = {1095-9203},
	pages = {53-57}
}

@article{MTMT:22867993,
	title = {ACTION OF TACHYKININS IN THE HIPPOCAMPUS: FACILITATION OF INHIBITORY DRIVE TO GABAergic INTERNEURONS},
	url = {https://m2.mtmt.hu/api/publication/22867993},
	author = {Ogier, R and Wrobel, LJ and Raggenbass, M},
	doi = {10.1016/j.neuroscience.2008.08.001},
	journal-iso = {NEUROSCIENCE},
	journal = {NEUROSCIENCE},
	volume = {156},
	unique-id = {22867993},
	issn = {0306-4522},
	year = {2008},
	eissn = {1873-7544},
	pages = {527-536}
}

@article{MTMT:22890358,
	title = {Slow GABA(A) mediated synaptic transmission in rat visual cortex},
	url = {https://m2.mtmt.hu/api/publication/22890358},
	author = {Sceniak, MP and MacIver, MB},
	doi = {10.1186/1471-2202-9-8},
	journal-iso = {BMC NEUROSCI},
	journal = {BMC NEUROSCIENCE},
	volume = {9},
	unique-id = {22890358},
	issn = {1471-2202},
	year = {2008},
	eissn = {1471-2202}
}

@article{MTMT:21502286,
	title = {Intra-hippocampal tonic inhibition influences formalin pain-induced pyramidal cell suppression, but not excitation in dorsal field CA1 of rat},
	url = {https://m2.mtmt.hu/api/publication/21502286},
	author = {Zheng, F and Khanna, S},
	doi = {10.1016/j.brainresbull.2008.09.004},
	journal-iso = {BRAIN RES BULL},
	journal = {BRAIN RESEARCH BULLETIN},
	volume = {77},
	unique-id = {21502286},
	issn = {0361-9230},
	year = {2008},
	eissn = {1873-2747},
	pages = {374-381}
}

@article{MTMT:25005231,
	title = {Presynaptic inhibition differentially shapes transmission in distinct circuits in the mouse retina},
	url = {https://m2.mtmt.hu/api/publication/25005231},
	author = {Eggers, Erika D and McCall, Maureen A and Lukasiewicz, Peter D},
	doi = {10.1113/jphysiol.2007.131763},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {582},
	unique-id = {25005231},
	issn = {0022-3751},
	year = {2007},
	eissn = {1469-7793},
	pages = {569-582}
}

@article{MTMT:25003084,
	title = {Role of the hippocampus-entorhinal cortex loop in the temporal lobe epilepsy},
	url = {https://m2.mtmt.hu/api/publication/25003084},
	author = {Labyt, Etienne and Wending, Fabrice},
	doi = {10.1684/epi.2007.0047},
	journal-iso = {EPILEPSIES},
	journal = {EPILEPSIES},
	volume = {19},
	unique-id = {25003084},
	issn = {1149-6576},
	year = {2007},
	pages = {11-22}
}

@article{MTMT:22882509,
	title = {Spike timing of lacunosom-moleculare targeting interneurons and CA3 pyramidal cells during high-frequency network oscillations in vitro},
	url = {https://m2.mtmt.hu/api/publication/22882509},
	author = {Spampanato, J and Mody, I},
	doi = {10.1152/jn.00188.2007},
	journal-iso = {J NEUROPHYSIOL},
	journal = {JOURNAL OF NEUROPHYSIOLOGY},
	volume = {98},
	unique-id = {22882509},
	issn = {0022-3077},
	year = {2007},
	eissn = {1522-1598},
	pages = {96-104}
}

@article{MTMT:1616467,
	title = {Differences between the scaling of miniature IPSCs and EPSCs recorded in the dendrites of CA1 mouse pyramidal neurons},
	url = {https://m2.mtmt.hu/api/publication/1616467},
	author = {Andrásfalvy, Bertalan and Mody, I},
	doi = {10.1113/jphysiol.2006.115428},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {576},
	unique-id = {1616467},
	issn = {0022-3751},
	abstract = {Anatomical studies have described inhibitory synaptic contacts on apical dendrites, and an abundant number of GABAergic synapses on the somata and proximal dendrites of CA1 pyramidal cells of the hippocampus. The number of inhibitory contacts decreases dramatically with distance from the soma, but the local electrophysiological characterization of these synapses at their site of origin in the dendrites is missing. We directly recorded dendritic GABA receptor-mediated inhibitory synaptic events in adult mouse hippocampal CA1 pyramidal neurons and compared them to excitatory synaptic currents recorded at the same sites. Miniature GABAergic events were evoked using localized application of a hyperosmotic solution to the apical dendrites in the vicinity of the dendritic whole-cell recording pipette. Glutamatergic synaptic events were blocked by kynurenic acid, leaving picrotoxin-sensitive IPSCs. We measured the amplitude and kinetic properties of mIPSCs at the soma and at three different dendritic locations. The amplitude of mIPSCs recorded at the various sites was similar along the somato-dendritic axis. The rise- and decay-times of local mIPSCs were also independent of the location of the synapses. The frequency of mIPSCs was 5 Hz at the soma, in contrast to < 0.5 Hz at dendritic sites, which could be increased to 10-20 Hz and 6-10 Hz, respectively, by our hyperosmotic stimulation protocol. Miniature glutamatergic events were evoked with the same protocol after blocking inhibitory synapses by bicucculine. The measured amplitudes increased along the somato-dendritic axis proportionally with their distance from the soma. The measured kinetic properties were independent of location. Consistent with the idea that IPSCs may have a restricted local effect in the dendrites, our data show a lack of distance-dependent scaling of miniature inhibitory synaptic events, in contrast to the scaling of excitatory events recorded at the same sites.},
	keywords = {Animals; MICE; Neural Inhibition/*physiology; Mice, Inbred C57BL; Electrophysiology; Excitatory Amino Acid Antagonists/pharmacology; Excitatory Postsynaptic Potentials/*physiology; Receptors, GABA/physiology; gamma-Aminobutyric Acid/physiology; Evoked Potentials/physiology; Synapses/drug effects/physiology; Patch-Clamp Techniques; Bicuculline/pharmacology; GABA Antagonists/pharmacology; Pyramidal Cells/drug effects/*physiology; Kynurenic Acid/pharmacology; Dendrites/drug effects/*physiology},
	year = {2006},
	eissn = {1469-7793},
	pages = {191-196}
}

@article{MTMT:27029657,
	title = {Interneurons targeting similar layers receive synaptic inputs with similar kinetics},
	url = {https://m2.mtmt.hu/api/publication/27029657},
	author = {Cossart, R and Petanjek, Z and Dumitriu, D and Hirsch, JC and Ben-Ari, Y and Esclapez, M and Bernard, C},
	doi = {10.1002/hipo.20169},
	journal-iso = {HIPPOCAMPUS},
	journal = {HIPPOCAMPUS},
	volume = {16},
	unique-id = {27029657},
	issn = {1050-9631},
	year = {2006},
	eissn = {1098-1063},
	pages = {408-420}
}

@article{MTMT:25005236,
	title = {Receptor and transmitter release properties set the time course of retinal inhibition},
	url = {https://m2.mtmt.hu/api/publication/25005236},
	author = {Eggers, Erika D and Lukasiewicz, Peter D},
	doi = {10.1523/JNEUROSCI.2591-06.2006},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {26},
	unique-id = {25005236},
	issn = {0270-6474},
	year = {2006},
	eissn = {1529-2401},
	pages = {9413-9425}
}

@article{MTMT:1290344,
	title = {Intrinsic and synaptic mechanisms determining the timing of neuron population activity during hippocampal theta oscillation},
	url = {https://m2.mtmt.hu/api/publication/1290344},
	author = {Orbán, Gergő and Kiss, Tamás and Érdi, Péter},
	doi = {10.1152/jn.01233.2005},
	journal-iso = {J NEUROPHYSIOL},
	journal = {JOURNAL OF NEUROPHYSIOLOGY},
	volume = {96},
	unique-id = {1290344},
	issn = {0022-3077},
	abstract = {Hippocampal theta (3-8 Hz) is a major electrophysiological activity in rodents, which can be found in primates and humans as well. During theta activity, pyramidal cells and different classes of interneurons were shown to discharge at different phases of the extracellular theta. A recent in vitro study has shown that theta-frequency oscillation can be elicited in a hippocampal CA1 slice by the activation of metabotropic glutamate receptors with similar pharmacological and physiological profile that was found in vivo. We constructed a conductance based three-population network model of the hippocampal CA1 region to study the specific roles of neuron types in the generation of the in vitro theta oscillation and the emergent network properties. Interactions between pairs of neuron populations were studied systematically to assess synchronization and delay properties. We showed that the circuitry consisting of pyramidal cells and two types of hippocampal interneurons [basket and oriens lacunosum-moleculare (O-LM) neurons] was able to generate coherent theta-frequency population oscillation. Furthermore, we found that hyperpolarization-activated nonspecific cation current in pyramidal cells, but not in O-LM neurons, plays an important role in the timing of spike generation, and thus synchronization of pyramidal cells. The model was shown to exhibit the same phase differences between neuron population activities found in vivo, supporting the idea that these patterns of activity are determined internal to the hippocampus.},
	year = {2006},
	eissn = {1522-1598},
	pages = {2889-2904}
}

@article{MTMT:10044118,
	title = {Low-dimensional maps encoding dynamics in entorhinal cortex and hippocampus},
	url = {https://m2.mtmt.hu/api/publication/10044118},
	author = {Pervouchine, DD and Netoff, TI and Rotstein, HG and White, JA and Cunningham, MO and Whittington, MA and Kopell, NJ},
	doi = {10.1162/neco.2006.18.11.2617},
	journal-iso = {NEURAL COMPUT},
	journal = {NEURAL COMPUTATION},
	volume = {18},
	unique-id = {10044118},
	issn = {0899-7667},
	year = {2006},
	eissn = {1530-888X},
	pages = {2617-2650}
}

@article{MTMT:25466669,
	title = {Analysis of the excitatory and inhibitory components of postsynaptic currents recorded in pyramidal neurons and interneurons in the rat hippocampus},
	url = {https://m2.mtmt.hu/api/publication/25466669},
	author = {Buldakova, SL and Tikhonov, DB and Magazanik, LG},
	doi = {10.1007/s11055-005-0133-y},
	journal-iso = {NEUROSCI BEHAV PHYSIOL},
	journal = {NEUROSCIENCE AND BEHAVIORAL PHYSIOLOGY},
	volume = {35},
	unique-id = {25466669},
	issn = {0097-0549},
	year = {2005},
	eissn = {1573-899X},
	pages = {835-843}
}

@article{MTMT:27029651,
	title = {Orthogonal arrangement of rhythm-generating microcircuits in the hippocampus},
	url = {https://m2.mtmt.hu/api/publication/27029651},
	author = {Gloveli, T and Dugladze, T and Rotstein, HG and Traub, RD and Monyer, H and Heinemann, U and Whittington, MA and Kopell, NJ},
	doi = {10.1073/pnas.0506259102},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {102},
	unique-id = {27029651},
	issn = {0027-8424},
	year = {2005},
	eissn = {1091-6490},
	pages = {13295-13300}
}

@book{MTMT:2979897,
	title = {Diversity in the Neuronal Machine: Order and Variability in Interneuronal Microcircuits},
	url = {https://m2.mtmt.hu/api/publication/2979897},
	isbn = {9780195177015},
	author = {Soltesz, Ivan},
	doi = {10.1093/acprof:oso/9780195177015.001.1},
	publisher = {OUP},
	unique-id = {2979897},
	year = {2005}
}

@article{MTMT:23827988,
	title = {Feed-forward facilitation of glutamate release by presynaptic GAB(A) receptors},
	url = {https://m2.mtmt.hu/api/publication/23827988},
	author = {Jang, IS and Ito, Y and Akaike, N},
	doi = {10.1016/j.neuroscience.2005.06.030},
	journal-iso = {NEUROSCIENCE},
	journal = {NEUROSCIENCE},
	volume = {135},
	unique-id = {23827988},
	issn = {0306-4522},
	year = {2005},
	eissn = {1873-7544},
	pages = {737-748}
}

@article{MTMT:109559,
	title = {Complementary roles of cholecystokinin- and parvalbumin-expressing GABAergic neurons in hippocampal network oscillations},
	url = {https://m2.mtmt.hu/api/publication/109559},
	author = {Klausberger, T and Marton, LF and O, Neill J and Huck, JH and Dalezios, Y and Fuentealba, P and Suen, WY and Papp, Edit and Kaneko, T and Watanabe, M and Csicsvari, J and Somogyi, Péter Pál},
	doi = {10.1523/JNEUROSCI.3269-05.2005},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {25},
	unique-id = {109559},
	issn = {0270-6474},
	abstract = {In the hippocampal CA1 area, a relatively homogenous population of pyramidal cells is accompanied by a diversity of GABAergic interneurons. Previously, we found that parvalbumin-expressing basket, axo-axonic, bistratified, and oriens-lacunosum moleculare cells, innervating different domains of pyramidal cells, have distinct firing patterns during network oscillations in vivo. A second family of interneurons, expressing cholecystokinin but not parvalbumin, is known to target the same domains of pyramidal cells as do the parvalbumin cells. To test the temporal activity of these independent and parallel GABAergic inputs, we recorded the precise spike timing of identified cholecystokinin interneurons during hippocampal network oscillations in anesthetized rats and determined their molecular expression profiles and synaptic targets. The cells were cannabinoid receptor type 1 immunopositive. Contrary to the stereotyped firing of parvalbumin interneurons, cholecystokinin-expressing basket and dendrite-innervating cells discharge, on average, with 1.7 +/- 2.0 Hz during high-frequency ripple oscillations in an episode- dependent manner. During theta oscillations, cholecystokinin-expressing interneurons fire with 8.8 +/- 3.3 Hz at a characteristic time on the ascending phase of theta waves (155 +/- 81), when place cells start firing in freely moving animals. The firing patterns of some interneurons recorded in drug- free behaving rats were similar to cholecystokinin cells in anesthetized animals. Our results demonstrate that cholecystokinin- and parvalbumin- expressing interneurons make different contributions to network oscillations and play distinct roles in different brain states. We suggest that the specific spike timing of cholecystokinin interneurons and their sensitivity to endocannabinoids might contribute to differentiate subgroups of pyramidal cells forming neuronal assemblies, whereas parvalbumin interneurons contribute to synchronizing the entire network.},
	year = {2005},
	eissn = {1529-2401},
	pages = {9782-9793}
}

@article{MTMT:27029647,
	title = {Stratum oriens horizontal interneurone diversity and hippocampal network dynamics},
	url = {https://m2.mtmt.hu/api/publication/27029647},
	author = {Maccaferri, G},
	doi = {10.1113/jphysiol.2004.077081},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {562},
	unique-id = {27029647},
	issn = {0022-3751},
	year = {2005},
	eissn = {1469-7793},
	pages = {73-80}
}

@article{MTMT:27660916,
	title = {Evoked electrical activity and immunocytochemical peculiarities of cultured excitatory and inhibitory neurons of the rat hippocampus},
	url = {https://m2.mtmt.hu/api/publication/27660916},
	author = {Moskalyuk, AA and Koval', OM and Fedulova, SA and Veselovskii, NS},
	doi = {10.1007/s11062-005-0063-x},
	journal-iso = {NEUROPHYSIOLOGY+},
	journal = {NEUROPHYSIOLOGY},
	volume = {37},
	unique-id = {27660916},
	issn = {0090-2977},
	year = {2005},
	eissn = {1573-9007},
	pages = {178-187}
}

@article{MTMT:22867961,
	title = {Cell-type specific GABA synaptic transmission and activity-dependent plasticity in rat hippocampal stratum radiatum interneurons},
	url = {https://m2.mtmt.hu/api/publication/22867961},
	author = {Patenaude, C and Massicotte, G and Lacaille, JC},
	doi = {10.1111/j.1460-9568.2005.04207.x},
	journal-iso = {EUR J NEUROSCI},
	journal = {EUROPEAN JOURNAL OF NEUROSCIENCE},
	volume = {22},
	unique-id = {22867961},
	issn = {0953-816X},
	year = {2005},
	eissn = {1460-9568},
	pages = {179-188}
}

@article{MTMT:27029259,
	title = {Slow and fast inhibition and an H-current interact to create a theta rhythm in a model of CA1 interneuron network},
	url = {https://m2.mtmt.hu/api/publication/27029259},
	author = {Rotstein, HG and Pervouchine, DD and Acker, CD and Gillies, MJ and White, JA and Buhl, EH and Whittington, MA and Kopell, N},
	doi = {10.1152/jn.00957.2004},
	journal-iso = {J NEUROPHYSIOL},
	journal = {JOURNAL OF NEUROPHYSIOLOGY},
	volume = {94},
	unique-id = {27029259},
	issn = {0022-3077},
	year = {2005},
	eissn = {1522-1598},
	pages = {1509-1518}
}

@article{MTMT:21884847,
	title = {Changes in mIPSCs and sIPSCs after kainate treatment: Evidence for loss of inhibitory input to dentate granule cells and possible compensatory responses},
	url = {https://m2.mtmt.hu/api/publication/21884847},
	author = {Shao, LR and Dudek, FE},
	doi = {10.1152/jn.01342.2004},
	journal-iso = {J NEUROPHYSIOL},
	journal = {JOURNAL OF NEUROPHYSIOLOGY},
	volume = {94},
	unique-id = {21884847},
	issn = {0022-3077},
	year = {2005},
	eissn = {1522-1598},
	pages = {952-960}
}

@article{MTMT:2086378,
	title = {Defined types of cortical interneurone structure space and spike timing in the hippocampus.},
	url = {https://m2.mtmt.hu/api/publication/2086378},
	author = {Somogyi, Péter Pál and Klausberger, T},
	doi = {10.1113/jphysiol.2004.078915},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {562},
	unique-id = {2086378},
	issn = {0022-3751},
	abstract = {The cerebral cortex encodes, stores and combines information about the internal and external environment in rhythmic activity of multiple frequency ranges. Neurones of the cortex can be defined, recognized and compared on the comprehensive application of the following measures: (i) brain area- and cell domain-specific distribution of input and output synapses, (ii) expression of molecules involved in cell signalling, (iii) membrane and synaptic properties reflecting the expression of membrane proteins, (iv) temporal structure of firing in vivo, resulting from (i)-(iii). Spatial and temporal measures of neurones in the network reflect an indivisible unity of evolutionary design, i.e. neurones do not have separate structure or function. The blueprint of this design is most easily accessible in the CA1 area of the hippocampus, where a relatively uniform population of pyramidal cells and their inputs follow an instantly recognizable laminated pattern and act within stereotyped network activity patterns. Reviewing the cell types and their spatio-temporal interactions, we suggest that CA1 pyramidal cells are supported by at least 16 distinct types of GABAergic neurone. During a given behaviour-contingent network oscillation, interneurones of a given type exhibit similar firing patterns. During different network oscillations representing two distinct brain states, interneurones of the same class show different firing patterns modulating their postsynaptic target-domain in a brain-state-dependent manner. These results suggest roles for specific interneurone types in structuring the activity of pyramidal cells via their respective target domains, and accurately timing and synchronizing pyramidal cell discharge, rather than providing generalized inhibition. Finally, interneurones belonging to different classes may fire preferentially at distinct time points during a given oscillation. As different interneurones innervate distinct domains of the pyramidal cells, the different compartments will receive GABAergic input differentiated in time. Such a dynamic, spatio-temporal, GABAergic control, which evolves distinct patterns during different brain states, is ideally suited to regulating the input integration of individual pyramidal cells contributing to the formation of cell assemblies and representations in the hippocampus and, probably, throughout the cerebral cortex.},
	keywords = {Animals; Humans; Hippocampus/cytology/*physiology; Electrophysiology; Theta rhythm; Brain/physiology; Interneurons/classification/*physiology; Cerebral Cortex/cytology/*physiology; Neurons/classification/*physiology/ultrastructure},
	year = {2005},
	eissn = {1469-7793},
	pages = {9-26}
}

@article{MTMT:25006528,
	title = {Cell type-specific synaptic dynamics of synchronized bursting in the juvenile CA3 rat hippocampus},
	url = {https://m2.mtmt.hu/api/publication/25006528},
	author = {Aradi, I and Maccaferri, G},
	doi = {10.1523/JNEUROSCI.2800-04.2004},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {24},
	unique-id = {25006528},
	issn = {0270-6474},
	year = {2004},
	eissn = {1529-2401},
	pages = {9681-9692}
}

@article{MTMT:27029231,
	title = {Membrane and network theta-rhythm generation in hippocampal slices},
	url = {https://m2.mtmt.hu/api/publication/27029231},
	author = {Karnup, SV},
	journal-iso = {ZH VYSSH NERV DEYAT+},
	journal = {ZHURNAL VYSSHEI NERVNOI DEYATELNOSTI IMENI I P PAVLOVA},
	volume = {54},
	unique-id = {27029231},
	issn = {0044-4677},
	year = {2004},
	eissn = {0044-4677},
	pages = {32-43}
}

@article{MTMT:2086376,
	title = {Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat.},
	url = {https://m2.mtmt.hu/api/publication/2086376},
	author = {Kogo, N and Dalezios, Y and Capogna, M and Ferraguti, F and Shigemoto, R and Somogyi, Péter Pál},
	doi = {10.1111/j.0953-816X.2004.03394.x},
	journal-iso = {EUR J NEUROSCI},
	journal = {EUROPEAN JOURNAL OF NEUROSCIENCE},
	volume = {19},
	unique-id = {2086376},
	issn = {0953-816X},
	abstract = {The release of GABA in synapses is modulated by presynaptic metabotropic glutamate receptors (mGluRs). We tested whether GABA release to identified hippocampal neurons is influenced by group III mGluR activation using the agonist L-(+)-2-amino-4-phosphonobutyric acid (L-AP4) on inhibitory postsynaptic currents (IPSCs) evoked in CA1 interneurons and pyramidal cells. In interneurons, characterized with biocytin and immunolabelling for somatostatin, evoked IPSCs were depressed by 50 micro m L-AP4 (activating mGluR4 and 8) to 68 +/- 6% of control, but they were rarely depressed in pyramidal cells (96 +/- 4% of control). At 300-500 micro m concentration (activating mGluR4, 7 and 8), L-AP4 depressed IPSCs in both interneurons (to 70 +/- 6%) and pyramidal cells (to 67 +/- 4%). The change in trial-to-trial variability and in paired-pulse depression indicated a presynaptic action. In interneurons, the degree of IPSC depression was variable (to 9-87%), and a third of IPSCs were not affected by L-AP4. The L-AP4-evoked IPSC depression was blocked by LY341495. The depression of IPSCs was similar in O-LM cells and other interneurons. The lack of cell-type selectivity and the similar efficacy of different concentrations of L-AP4 suggest that several group III mGluRs are involved in the depression of IPSCs. Electron microscopic immunocytochemistry confirmed that mGluR4, mGluR7a and mGluR8a occur in the presynaptic active zone of GABAergic terminals on interneurons, but not on those innervating pyramidal cells. The high variability of L-AP4-evoked IPSC suppression is in line with the selective expression of presynaptic mGluRs by several distinct types of GABAergic neuron innervating each interneuron type.},
	keywords = {Animals; RATS; Hippocampus/*cytology; Microscopy, Immunoelectron/methods; Immunohistochemistry/methods; Cell Count/methods; Drug Interactions; Dose-Response Relationship, Drug; Time Factors; Rats, Wistar; Animals, Newborn; Horseradish Peroxidase/metabolism; Amino Acids/pharmacology; Statistics, Nonparametric; gamma-Aminobutyric Acid/*metabolism; Excitatory Amino Acid Antagonists/pharmacology; Membrane Potentials/drug effects; Patch-Clamp Techniques; Somatostatin/metabolism; Lysine/*analogs & derivatives/metabolism; Xanthenes/pharmacology; Pyramidal Cells/drug effects/*metabolism/ultrastructure; 2-Amino-5-phosphonovalerate/pharmacology; Synapses/drug effects/ultrastructure; Propionic Acids/pharmacology; Receptors, Metabotropic Glutamate/agonists/*metabolism/ultrastructure; Neural Inhibition/*drug effects; Interneurons/classification/drug effects/*metabolism/ultrastructure},
	year = {2004},
	eissn = {1460-9568},
	pages = {2727-2740}
}

@article{MTMT:10044132,
	title = {Static, transient and permanent organization of GABA(A) receptor expression in calbindin-positive interneurons in response to amygdala kindled seizures},
	url = {https://m2.mtmt.hu/api/publication/10044132},
	author = {Meguro, R and Lu, J and Gavrilovici, C and Poulter, MO},
	doi = {10.1111/j.1471-4159.2004.02701.x},
	journal-iso = {J NEUROCHEM},
	journal = {JOURNAL OF NEUROCHEMISTRY},
	volume = {91},
	unique-id = {10044132},
	issn = {0022-3042},
	year = {2004},
	eissn = {1471-4159},
	pages = {144-154}
}

@article{MTMT:2941536,
	title = {Rapid deletion of mossy cells does not result in a hyperexcitable dentate gyrus: Implications for epileptogenesis},
	url = {https://m2.mtmt.hu/api/publication/2941536},
	author = {Ratzliff, ADH and Howard, AL and Santhakumar, V and Osapay, I and Soltesz, Ivan},
	doi = {10.1523/JNEUROSCI.5191-03.2004},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {24},
	unique-id = {2941536},
	issn = {0270-6474},
	abstract = {Loss of cells from the hilus of the dentate gyrus is a major histological hallmark of human temporal lobe epilepsy. Hilar mossy cells, in particular, are thought to show dramatic numerical reductions in pathological conditions, and one prominent theory of epileptogenesis is based on the assumption that mossy cell loss directly results in granule cell hyperexcitability. However, whether it is the disappearance of hilar mossy cells from the dentate gyrus circuitry after various insults or the subsequent synaptic - cellular alterations ( e. g., reactive axonal sprouting) that lead to dentate hyperexcitability has not been rigorously tested, because of the lack of available techniques to rapidly remove specific classes of nonprincipal cells from neuronal networks. We developed a fast, cell-specific ablation technique that allowed the targeted lesioning of either mossy cells or GABAergic interneurons in horizontal as well as axial ( longitudinal) slices of the hippocampus. The results demonstrate that mossy cell deletion consistently decreased the excitability of granule cells to perforant path stimulation both within and outside of the lamella where the mossy cell ablation took place. In contrast, ablation of interneurons caused the expected increase in excitability, and control aspirations of the hilar neuropil or of interneurons in the presence of GABA receptor blockers caused no alteration in granule cell excitability. These data do not support the hypothesis that loss of mossy cells from the dentate hilus after seizures or traumatic brain injury directly results in hyperexcitability.},
	keywords = {IN-VIVO; NEURONS; TEMPORAL-LOBE EPILEPSY; EPILEPSY; INHIBITORY INTERNEURONS; dentate gyrus; SYNAPTIC CONNECTIONS; GRANULE CELLS; molecular layer; hyperexcitability; hippocampal interneurons; RECEPTOR SUBUNIT EXPRESSION; dormant basket cell hypothesis; hilar cell loss; mossy cell; rat},
	year = {2004},
	eissn = {1529-2401},
	pages = {2259-2269}
}

@article{MTMT:25005890,
	title = {Major differences in inhibitory synaptic transmission onto two neocortical interneuron subclasses},
	url = {https://m2.mtmt.hu/api/publication/25005890},
	author = {Bacci, A and Rudolph, U and Huguenard, JR and Prince, DA},
	doi = {10.1523/jneurosci.23-29-09664.2003},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {23},
	unique-id = {25005890},
	issn = {0270-6474},
	year = {2003},
	eissn = {1529-2401},
	pages = {9664-9674}
}

@article{MTMT:25005684,
	title = {Functional localization of cannabinoid receptors and endogenous cannabinoid production in distinct neuron populations of the hippocampus},
	url = {https://m2.mtmt.hu/api/publication/25005684},
	author = {Hoffman, AF and Riegel, AC and Lupica, CR},
	doi = {10.1046/j.1460-9568.2003.02773.x},
	journal-iso = {EUR J NEUROSCI},
	journal = {EUROPEAN JOURNAL OF NEUROSCIENCE},
	volume = {18},
	unique-id = {25005684},
	issn = {0953-816X},
	year = {2003},
	eissn = {1460-9568},
	pages = {524-534}
}

@article{MTMT:10044356,
	title = {Neurosteroid effects on GABAergic synaptic plasticity in hippocampus},
	url = {https://m2.mtmt.hu/api/publication/10044356},
	author = {Hsu, FC and Waldeck, R and Faber, DS and Smith, SS},
	doi = {10.1152/jn.00780.2002},
	journal-iso = {J NEUROPHYSIOL},
	journal = {JOURNAL OF NEUROPHYSIOLOGY},
	volume = {89},
	unique-id = {10044356},
	issn = {0022-3077},
	year = {2003},
	eissn = {1522-1598},
	pages = {1929-1940}
}

@article{MTMT:10058143,
	title = {GABA transporter-1 (GAT1)-Deficient mice: Differential tonic activation of GABA(A) versus GABA(B) receptors in the hippocampus},
	url = {https://m2.mtmt.hu/api/publication/10058143},
	author = {Jensen, K and Chiu, CS and Sokolova, I and Lester, HA and Mody, I},
	doi = {10.1152/jn.00240.2003},
	journal-iso = {J NEUROPHYSIOL},
	journal = {JOURNAL OF NEUROPHYSIOLOGY},
	volume = {90},
	unique-id = {10058143},
	issn = {0022-3077},
	year = {2003},
	eissn = {1522-1598},
	pages = {2690-2701}
}

@article{MTMT:27029615,
	title = {Patterns of expression of neuropeptides in GABAergic nonprincipal neurons in the mouse hippocampus: Quantitative analysis with optical disector},
	url = {https://m2.mtmt.hu/api/publication/27029615},
	author = {Jinno, S and Kosaka, T},
	doi = {10.1002/cne.10700},
	journal-iso = {J COMP NEUROL},
	journal = {JOURNAL OF COMPARATIVE NEUROLOGY},
	volume = {461},
	unique-id = {27029615},
	issn = {0021-9967},
	year = {2003},
	eissn = {1096-9861},
	pages = {333-349}
}

@article{MTMT:25007158,
	title = {Interneuron Diversity series: Hippocampal interneuron classifications - making things as simple as possible, not simpler},
	url = {https://m2.mtmt.hu/api/publication/25007158},
	author = {Maccaferri, G and Lacaille, JC},
	doi = {10.1016/j.tins.2003.08.002},
	journal-iso = {TRENDS NEUROSCI},
	journal = {TRENDS IN NEUROSCIENCES},
	volume = {26},
	unique-id = {25007158},
	issn = {0166-2236},
	abstract = {The nervous system is made up of many specific types of neuron intricately intertwined to form complex networks. Identifying and defining the characteristic features of the many different neuronal types is essential for achieving a cellular understanding of complex activity from perception to cognition. So far, cortical GABAergic interneurons have represented the epitome of cellular diversity in the CNS. Despite the desperate need for effective classification criteria allowing a common language among neuroscientists, interneurons still evoke memories of Babel. Several approaches are now available to overcome the challenges and problems associated with the various classification systems used so far.},
	keywords = {hippocampus; DEPOLARIZATION; PERCEPTION; review; MORPHOLOGY; priority journal; nonhuman; brain cortex; cognition; Nervous System; Neurochemistry; 4 aminobutyric acid; interneuron; hyperpolarization; nerve cell network},
	year = {2003},
	eissn = {1878-108X},
	pages = {564-571}
}

@article{MTMT:2941545,
	title = {Modulation of network behaviour by changes in variance in interneuronal properties},
	url = {https://m2.mtmt.hu/api/publication/2941545},
	author = {Aradi, I and Soltesz, Ivan},
	doi = {10.1113/jphysiol.2001.013054},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {538},
	unique-id = {2941545},
	issn = {0022-3751},
	abstract = {Interneurones are important regulators of neuronal networks. The conventional approach to interneurones is to focus on the mean values of various parameters. Here we tested the hypothesis that changes in the variance of interneuronal properties (e.g. in the degree of scattering of parameter values of individual cells around the population mean) may modify the behaviour of networks. Biophysically based multicompartmental models of principal cells and interneurones showed that changes in the variance in the electrophysiological and anatomical properties of interneurones significantly alter the input-output functions, rhythmicity and synchrony of principal cells, even if the mean values were unchanged. In most cases, increased heterogeneity in interneurones resulted in stronger inhibition of principal cell firing; however, there were parameter ranges where increased interneuronal variance decreased the inhibition of principal cells. Electrophysiological recordings showed that the variance in the resting membrane potential of CA1 stratum oriens interneurones persistently increased following experimental complex febrile seizures in developing rats, without a change in the mean resting membrane potential, indicating that lasting alterations in interneuronal heterogeneity can take place in real neuronal systems. These computational and experimental data demonstrate that modifications in interneuronal population variance influence the behaviour of neuronal networks, and suggest a physiological role for interneuronal diversity. Furthermore, the results indicate that interneuronal heterogeneity can change in neurological diseases, and raise the possibility that neuromodulators may act by regulating the variance of key parameters in interneuronal populations.},
	keywords = {LONG-TERM; RAT HIPPOCAMPUS; INHIBITORY INTERNEURONS; traumatic brain injury; HIPPOCAMPUS IN-VITRO; FEBRILE SEIZURES; GRANULE CELLS; Pyramidal Neurons; CA1 INTERNEURONS; DENTATE BASKET CELLS},
	year = {2002},
	eissn = {1469-7793},
	pages = {227-251}
}

@article{MTMT:2138527,
	title = {Cholecystokinin-immunopositive basket and Schaffer collateral-associated interneurones target different domains of pyramidal cells in the CA1 area of the rat hippocampus.},
	url = {https://m2.mtmt.hu/api/publication/2138527},
	author = {Cope, DW and Maccaferri, G and Marton, LF and Roberts, JD and Cobden, PM and Somogyi, Péter Pál},
	doi = {10.1016/S0306-4522(01)00440-7},
	journal-iso = {NEUROSCIENCE},
	journal = {NEUROSCIENCE},
	volume = {109},
	unique-id = {2138527},
	issn = {0306-4522},
	abstract = {Two types of GABAergic interneurone are known to express cholecystokinin-related peptides in the isocortex: basket cells, which preferentially innervate the somata and proximal dendrites of pyramidal cells; and double bouquet cells, which innervate distal dendrites and dendritic spines. In the hippocampus, cholecystokinin immunoreactivity has only been reported in basket cells. However, at least eight distinct GABAergic interneurone types terminate in the dendritic domain of CA1 pyramidal cells, some of them with as yet undetermined neurochemical characteristics. In order to establish whether more than one population of cholecystokinin-expressing interneurone exist in the hippocampus, we have performed whole-cell current clamp recordings from interneurones located in the stratum radiatum of the hippocampal CA1 region of developing rats. Recorded neurones were filled with biocytin to reveal their axonal targets, and were tested for the presence of pro-cholecystokinin immunoreactivity. The results show that two populations of cholecystokinin-immunoreactive interneurones exist in the CA1 area (n=15 positive cells). Cholecystokinin-positive basket cells (53%) preferentially innervate stratum pyramidale and adjacent strata oriens and radiatum. A second population of cholecystokinin-positive cells, previously described as Schaffer collateral-associated interneurones [Vida et al. (1998) J. Physiol. 506, 755-773], have axons that ramify almost exclusively in strata radiatum and oriens, overlapping with the Schaffer collateral/commissural pathway originating from CA3 pyramidal cells. Two of seven of the Schaffer collateral-associated cells were also immunopositive for calbindin. Soma position and orientation in stratum radiatum, the number and orientation of dendrites, and the passive and active membrane properties of the two cell populations are only slightly different. In addition, in stratum radiatum and its border with lacunosum of perfusion-fixed hippocampi, 31.6+/-3.8% (adult) or 26.8+/-2.9% (postnatal day 17-20) of cholecystokinin-positive cells were also immunoreactive for calbindin. Therefore, at least two populations of pro-cholecystokinin-immunopositive interneurones, basket and Schaffer collateral-associated cells, exist in the CA1 area of the hippocampus, and are probably homologous to cholecystokinin-immunopositive basket and double bouquet cells in the isocortex. It is not known if the GABAergic terminals of double bouquet cells are co-aligned with specific glutamatergic inputs. However, in the hippocampal CA1 area, it is clear that the terminals of Schaffer collateral-associated cells are co-stratified with the glutamatergic input from the CA3 area, with as yet unknown functional consequences. The division of the postsynaptic neuronal surface by two classes of GABAergic cell expressing cholecystokinin in both the hippocampus and isocortex provides further evidence for the uniform synaptic organisation of the cerebral cortex.},
	keywords = {Animals; Male; immunohistochemistry; RATS; Calcium-Binding Protein, Vitamin D-Dependent/metabolism; Synaptic Transmission/*physiology; Action Potentials/physiology; Rats, Wistar; Animals, Newborn; Aging/metabolism; gamma-Aminobutyric Acid/*metabolism; Neural Inhibition/physiology; Organ Culture Techniques; Interneurons/cytology/*metabolism; Cholecystokinin/*metabolism; Lysine/*analogs & derivatives/diagnostic use; Axons/*metabolism/ultrastructure; Pyramidal Cells/cytology/*metabolism; Hippocampus/cytology/growth & development/*metabolism},
	year = {2002},
	eissn = {1873-7544},
	pages = {63-80}
}

@article{MTMT:109159,
	title = {Simultaneous activation of gamma and theta network oscillations in rat hippocampal slice cultures},
	url = {https://m2.mtmt.hu/api/publication/109159},
	author = {Fischer, Y and Wittner, Lucia and Freund, Tamás and Gähwiler, BH},
	doi = {10.1113/jphysiol.2001.013050},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {539},
	unique-id = {109159},
	issn = {0022-3751},
	year = {2002},
	eissn = {1469-7793},
	pages = {857-868},
	orcid-numbers = {Wittner, Lucia/0000-0001-6800-0953}
}

@article{MTMT:109363,
	title = {Comparison of single NMDA receptor channels recorded on hippocampal principal cells and oriens/alveus interneurons projecting to stratum lacunosum-moleculare (O-LM cells)},
	url = {https://m2.mtmt.hu/api/publication/109363},
	author = {Hájos, Norbert and Freund, Tamás and Mody, I},
	doi = {10.1556/ABiol.53.2002.4.7},
	journal-iso = {ACTA BIOL HUNG},
	journal = {ACTA BIOLOGICA HUNGARICA (1983-2018)},
	volume = {53},
	unique-id = {109363},
	issn = {0236-5383},
	year = {2002},
	eissn = {1588-256X},
	pages = {465-472}
}

@article{MTMT:2138092,
	title = {Cell type- and input-specific differences in the number and subtypes of synaptic GABA(A) receptors in the hippocampus.},
	url = {https://m2.mtmt.hu/api/publication/2138092},
	author = {Klausberger, T and Roberts, JD and Somogyi, Péter Pál},
	doi = {10.1523/jneurosci.22-07-02513.2002},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {22},
	unique-id = {2138092},
	issn = {0270-6474},
	abstract = {Networks of parvalbumin (PV)-expressing basket cells are implicated in synchronizing cortical neurons at various frequencies, through GABA(A) receptor-mediated synaptic action. These cells are interconnected by GABAergic synapses and gap junctions, and converge with a different class of cholecystokinin-expressing, PV-negative basket cells onto pyramidal cells. To define the molecular specializations in the synapses of the two basket cell populations, we used quantitative electron microscopic immunogold localization of GABA(A) receptors. Synapses formed by PV-positive basket cells on the somata of pyramidal cells had several-fold higher density of alpha1 subunit-containing receptors than synapses made by PV-negative basket cells, most of which were immunonegative. The density of the beta2/3 subunits was similar in the two populations of synapse, indicating similar overall receptor density. Synapses interconnecting parvalbumin-expressing basket cells contained a 3.6 times higher overall density of GABA(A) receptor (beta2/3 subunits) and 3.2 times higher density of alpha1 subunit labeling compared with synapses formed by boutons of PV-positive basket cells on pyramidal cells. Thus, PV-positive basket cells mainly act through alpha1 subunit-containing GABA(A) receptors, but the receptor density depends on the postsynaptic cell type. These observations, together with previously reported enrichment of the alpha2 subunit-containing receptors in synapses made by PV-negative basket cells, indicate that the number and subtypes of GABA(A) receptors present in different synapse populations are regulated by both presynaptic and postsynaptic influences. The high number of GABA(A) receptors in synapses on basket cells might contribute to the precisely timed phasing of basket cell activity.},
	keywords = {Animals; Male; immunohistochemistry; RATS; Synapses/*metabolism/ultrastructure; Rats, Wistar; Microscopy, Immunoelectron; Hippocampus/cytology/*metabolism/ultrastructure; Receptors, GABA-A/*classification/*metabolism; Pyramidal Cells/metabolism/ultrastructure; *Protein Subunits},
	year = {2002},
	eissn = {1529-2401},
	pages = {2513-2521}
}

@article{MTMT:27029593,
	title = {Physiological and morphological diversity of immunocytochemically defined parvalbumin- and cholecystokinin-positive interneurones in CA1 of the adult rat hippocampus},
	url = {https://m2.mtmt.hu/api/publication/27029593},
	author = {Pawelzik, H and Hughes, DI and Thomson, AM},
	doi = {10.1002/cne.10118},
	journal-iso = {J COMP NEUROL},
	journal = {JOURNAL OF COMPARATIVE NEUROLOGY},
	volume = {443},
	unique-id = {27029593},
	issn = {0021-9967},
	year = {2002},
	eissn = {1096-9861},
	pages = {346-367}
}

@article{MTMT:23269608,
	title = {GABA application to hippocampal CA3 or CA1 stratum lacunosum-moleculare excites an interneuron network},
	url = {https://m2.mtmt.hu/api/publication/23269608},
	author = {Perkins, KL},
	doi = {10.1152/jn.00430.2001},
	journal-iso = {J NEUROPHYSIOL},
	journal = {JOURNAL OF NEUROPHYSIOLOGY},
	volume = {87},
	unique-id = {23269608},
	issn = {0022-3077},
	year = {2002},
	eissn = {1522-1598},
	pages = {1404-1414}
}

@article{MTMT:21503064,
	title = {A fundamental oscillatory state of isolated rodent hippocampus},
	url = {https://m2.mtmt.hu/api/publication/21503064},
	author = {Wu, CP and Shen, H and Luk, WP and Zhang, L},
	doi = {10.1113/jphysiol.2001.013441},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {540},
	unique-id = {21503064},
	issn = {0022-3751},
	year = {2002},
	eissn = {1469-7793},
	pages = {509-527}
}

@article{MTMT:27029581,
	title = {Nicotinic acetylcholine receptor alpha 7 and alpha 4 beta 2 subtypes differentially control GABAergic input to CA1 neurons in rat hippocampus},
	url = {https://m2.mtmt.hu/api/publication/27029581},
	author = {Alkondon, M and Albuquerque, EX},
	doi = {10.1152/jn.2001.86.6.3043},
	journal-iso = {J NEUROPHYSIOL},
	journal = {JOURNAL OF NEUROPHYSIOLOGY},
	volume = {86},
	unique-id = {27029581},
	issn = {0022-3077},
	year = {2001},
	eissn = {1522-1598},
	pages = {3043-3055}
}

@article{MTMT:27029571,
	title = {Rapid signaling at inhibitory synapses in a dentate gyrus interneuron network},
	url = {https://m2.mtmt.hu/api/publication/27029571},
	author = {Bartos, M and Vida, I and Frotscher, M and Geiger, JRP and Jonas, P},
	doi = {10.1523/JNEUROSCI.21-08-02687.2001},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {21},
	unique-id = {27029571},
	issn = {0270-6474},
	year = {2001},
	eissn = {1529-2401},
	pages = {2687-2698}
}

@article{MTMT:25005911,
	title = {Heterogeneity of functional GABA(A) receptors in rat dentate gyrus neurons revealed by a change in response to drugs during the whole-cell current time-course},
	url = {https://m2.mtmt.hu/api/publication/25005911},
	author = {Lim, MSF and Birnir, B},
	doi = {10.1016/S0028-3908(01)00032-6},
	journal-iso = {NEUROPHARMACOLOGY},
	journal = {NEUROPHARMACOLOGY},
	volume = {40},
	unique-id = {25005911},
	issn = {0028-3908},
	year = {2001},
	eissn = {1873-7064},
	pages = {1034-1043}
}

@article{MTMT:10049481,
	title = {Sensitivity of synaptic GABA(A) receptors to allosteric modulators in hippocampal oriens-alveus interneurons},
	url = {https://m2.mtmt.hu/api/publication/10049481},
	author = {Patenaude, C and Nurse, S and Lacaille, JC},
	doi = {10.1002/syn.1057},
	journal-iso = {SYNAPSE},
	journal = {SYNAPSE},
	volume = {41},
	unique-id = {10049481},
	issn = {0887-4476},
	year = {2001},
	eissn = {1098-2396},
	pages = {29-39}
}

@article{MTMT:27029580,
	title = {Gap junctions between interneuron dendrites can enhance synchrony of gamma oscillations in distributed networks},
	url = {https://m2.mtmt.hu/api/publication/27029580},
	author = {Traub, RD and Kopell, N and Bibbig, A and Buhl, EH and LeBeau, FEN and Whittington, MA},
	doi = {10.1523/JNEUROSCI.21-23-09478.2001},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {21},
	unique-id = {27029580},
	issn = {0270-6474},
	year = {2001},
	eissn = {1529-2401},
	pages = {9478-9486}
}

@article{MTMT:108823,
	title = {Cell type- and synapse-specific variability in synaptic GABA~A receptor occupancy},
	url = {https://m2.mtmt.hu/api/publication/108823},
	author = {Hájos, Norbert and Nusser, Zoltán and Rancz, Ede and Freund, Tamás and Mody, I},
	doi = {10.1046/j.1460-9568.2000.00964.x},
	journal-iso = {EUR J NEUROSCI},
	journal = {EUROPEAN JOURNAL OF NEUROSCIENCE},
	volume = {12},
	unique-id = {108823},
	issn = {0953-816X},
	year = {2000},
	eissn = {1460-9568},
	pages = {810-818}
}

@article{MTMT:25005928,
	title = {Developmental change in GABA(A) receptor desensitization kinetics and its role in synapse function in rat cortical neurons},
	url = {https://m2.mtmt.hu/api/publication/25005928},
	author = {Hutcheon, B and Morley, P and Poulter, MO},
	doi = {10.1111/j.1469-7793.2000.t01-5-00003.xm},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {522},
	unique-id = {25005928},
	issn = {0022-3751},
	year = {2000},
	eissn = {1469-7793},
	pages = {3-17}
}

@article{MTMT:2138095,
	title = {Cell surface domain specific postsynaptic currents evoked by identified GABAergic neurones in rat hippocampus in vitro.},
	url = {https://m2.mtmt.hu/api/publication/2138095},
	author = {Maccaferri, G and Roberts, JD and Szűcs, Péter and Cottingham, CA and Somogyi, Péter Pál},
	doi = {10.1111/j.1469-7793.2000.t01-3-00091.x},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {524},
	unique-id = {2138095},
	issn = {0022-3751},
	abstract = {1. Inhibitory postsynaptic currents (IPSCs) evoked in CA1 pyramidal cells (n = 46) by identified interneurones (n = 43) located in str. oriens were recorded in order to compare their functional properties and to determine the effect of synapse location on the apparent IPSC kinetics as recorded using somatic voltage clamp at -70 mV and nearly symmetrical [Cl-]. 2. Five types of visualised presynaptic interneurone, oriens-lacunosum moleculare (O-LMC), basket (BC), axo-axonic (AAC), bistratified (BiC) and oriens-bistratified (O-BiC) cells, were distinguished by immunocytochemistry and/or synapse location using light and electron microscopy. 3. Somatostatin immunoreactive O-LMCs, innervating the most distal dendritic shafts and spines, evoked the smallest amplitude (26 +/- 10 pA, s.e.m., n = 8) and slowest IPSCs (10-90 % rise time, 6.2 +/- 0.6 ms; decay, 20.8 +/- 1.7 ms, n = 8), with no paired-pulse modulation of the second IPSC (93 +/- 4 %) at 100 ms interspike interval. In contrast, parvalbumin-positive AACs evoked larger amplitude (308 +/- 103 pA, n = 7) and kinetically faster (rise time, 0.8 +/- 0.1 ms; decay 11.2 +/- 0.9 ms, n = 7) IPSCs showing paired-pulse depression (to 68 +/- 5 %, n = 6). Parvalbumin- or CCK-positive BCs (n = 9) terminating on soma/dendrites, BiCs (n = 4) and O-BiCs (n = 7) innervating dendrites evoked IPSCs with intermediate kinetic parameters. The properties of IPSCs and sensitivity to bicuculline indicated that they were mediated by GABAA receptors. 4. In three cases, kinetically complex, multiphasic IPSCs, evoked by an action potential in the recorded basket cells, suggested that coupled interneurones, possibly through electrotonic junctions, converged on the same postsynaptic neurone. 5. The population of O-BiCs (4 of 4 somatostatin positive) characterised in this study had horizontal dendrites restricted to str. oriens/alveus and innervated stratum radiatum and oriens. Other BiCs had radial dendrites as described earlier. The parameters of IPSCs evoked by BiCs and O-BiCs showed the largest cell to cell variation, and a single interneurone could evoke both small and slow as well as large and relatively fast IPSCs. 6. The kinetic properties of the somatically recorded postsynaptic current are correlated with the innervated cell surface domain. A significant correlation of rise and decay times for the overall population of unitary IPSCs suggests that electrotonic filtering of distal responses is a major factor for the location and cell type specific differences of unitary IPSCs, but molecular heterogeneity of postsynaptic GABAA receptors may also contribute to the observed kinetic differences. Furthermore, domain specific differences in the short-term plasticity of the postsynaptic response indicate a differentiation of interneurones in activity-dependent responses.},
	keywords = {Animals; RATS; KINETICS; Parvalbumins/analysis; Synaptic Transmission/*physiology; gamma-Aminobutyric Acid/*physiology; Rats, Wistar; Cell Membrane/physiology; Excitatory Postsynaptic Potentials/*physiology; Neurons/cytology/*physiology; Hippocampus/*physiology; Receptors, GABA-A/physiology; Patch-Clamp Techniques; Bicuculline/pharmacology; Synapses/*physiology/ultrastructure; Somatostatin/analysis; Axons/physiology/ultrastructure; Dendrites/physiology/ultrastructure; Cholecystokinin/pharmacology; Interneurons/cytology/physiology},
	year = {2000},
	eissn = {1469-7793},
	pages = {91-116},
	orcid-numbers = {Szűcs, Péter/0000-0003-4635-6427}
}

@article{MTMT:27029555,
	title = {Novel hippocampal interneuronal subtypes identified using transgenic mice that express green fluorescent protein in GABAergic interneurons},
	url = {https://m2.mtmt.hu/api/publication/27029555},
	author = {Oliva, AA and Jiang, MH and Lam, T and Smith, KL and Swann, JW},
	doi = {10.1523/JNEUROSCI.20-09-03354.2000},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {20},
	unique-id = {27029555},
	issn = {0270-6474},
	year = {2000},
	eissn = {1529-2401},
	pages = {3354-3368}
}

@article{MTMT:10044158,
	title = {Mechanisms involved in tetanus-induced potentiation of fast IPSCs in rat hippocampal CA1 neurons},
	url = {https://m2.mtmt.hu/api/publication/10044158},
	author = {Shew, T and Yip, S and Sastry, BR},
	doi = {10.1152/jn.2000.83.6.3388},
	journal-iso = {J NEUROPHYSIOL},
	journal = {JOURNAL OF NEUROPHYSIOLOGY},
	volume = {83},
	unique-id = {10044158},
	issn = {0022-3077},
	year = {2000},
	eissn = {1522-1598},
	pages = {3388-3401}
}

@article{MTMT:25002836,
	title = {Networks of interneurons with fast and slow gamma-aminobutyric acid type A (GABA(A)) kinetics provide substrate for mixed gamma-theta rhythm},
	url = {https://m2.mtmt.hu/api/publication/25002836},
	author = {White, JA and Banks, MI and Pearce, RA and Kopell, NJ},
	doi = {10.1073/pnas.100124097},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {97},
	unique-id = {25002836},
	issn = {0027-8424},
	year = {2000},
	eissn = {1091-6490},
	pages = {8128-8133}
}

@article{MTMT:27029529,
	title = {IPSPs elicited in CA1 pyramidal cells by putative basket cells in slices of adult rat hippocampus},
	url = {https://m2.mtmt.hu/api/publication/27029529},
	author = {Ali, AB and Bannister, AP and Thomson, AM},
	doi = {10.1046/j.1460-9568.1999.00592.x},
	journal-iso = {EUR J NEUROSCI},
	journal = {EUROPEAN JOURNAL OF NEUROSCIENCE},
	volume = {11},
	unique-id = {27029529},
	issn = {0953-816X},
	year = {1999},
	eissn = {1460-9568},
	pages = {1741-1753}
}

@article{MTMT:10324320,
	title = {Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices},
	url = {https://m2.mtmt.hu/api/publication/10324320},
	author = {Alkondon, M and Pereira, EFR and Eisenberg, HM and Albuquerque, EX},
	doi = {10.1523/jneurosci.19-07-02693.1999},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {19},
	unique-id = {10324320},
	issn = {0270-6474},
	year = {1999},
	eissn = {1529-2401},
	pages = {2693-2705}
}

@article{MTMT:23827173,
	title = {On the synchronizing mechanisms of tetanically induced hippocampal oscillations},
	url = {https://m2.mtmt.hu/api/publication/23827173},
	author = {Bracci, E and Vreugdenhil, M and Hack, SP and Jefferys, JGR},
	doi = {10.1523/jneurosci.19-18-08104.1999},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {19},
	unique-id = {23827173},
	issn = {0270-6474},
	year = {1999},
	eissn = {1529-2401},
	pages = {8104-8113}
}

@article{MTMT:27029533,
	title = {Cholinergic induction of theta-frequency oscillations in hippocampal inhibitory interneurons and pacing of pyramidal cell firing},
	url = {https://m2.mtmt.hu/api/publication/27029533},
	author = {Chapman, CA and Lacaille, JC},
	doi = {10.1523/jneurosci.19-19-08637.1999},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {19},
	unique-id = {27029533},
	issn = {0270-6474},
	year = {1999},
	eissn = {1529-2401},
	pages = {8637-8645}
}

@article{MTMT:25003827,
	title = {Intrinsic theta-frequency membrane potential oscillations in hippocampal CA1 interneurons of stratum lacunosum-moleculare},
	url = {https://m2.mtmt.hu/api/publication/25003827},
	author = {Chapman, CA and Lacaille, JC},
	doi = {10.1152/jn.1999.81.3.1296},
	journal-iso = {J NEUROPHYSIOL},
	journal = {JOURNAL OF NEUROPHYSIOLOGY},
	volume = {81},
	unique-id = {25003827},
	issn = {0022-3077},
	year = {1999},
	eissn = {1522-1598},
	pages = {1296-1307}
}