TY - JOUR AU - Figueiredo, Marcos V. D'Amato AU - Alexiou, George AU - Laube, Kaito A. Carvalho AU - Manfroi, Gregori AU - Rehder, Roberta TI - Novel concepts in the pathogenesis of hydrocephalus JF - CHILDS NERVOUS SYSTEM J2 - CHILD NERV SYST VL - 39 PY - 2023 IS - 5 SP - 1245 EP - 1252 PG - 8 SN - 0256-7040 DO - 10.1007/s00381-023-05891-7 UR - https://m2.mtmt.hu/api/publication/33842676 ID - 33842676 N1 - Funding Agency and Grant Number: Department of Neurosurgery of Santa Marcelina Hospital; Hospital do Coracao; University Hospital of Ioannina Funding text: We acknowledge the general support from the Department of Neurosurgery of Santa Marcelina Hospital, Hospital do Coracao, and University Hospital of Ioannina. AB - PurposeHydrocephalus is a multifactorial neurological disorder and one of the most common neurosurgical conditions characterized by excessive cerebrospinal fluid (CSF) accumulation within the brain's ventricles. It can result in dilatation of the ventricular system caused by the inadequate passage of CSF from its point of production within the ventricles to its point of absorption into the systemic circulation. Recent findings on the genetics and molecular studies of hydrocephalus have the potential to improve treatment and quality of life.MethodsReview of literature on the novel studies of the pathogenesis of hydrocephalus.ConclusionMolecular studies on the pathogenesis of hydrocephalus have provided a means to improve the treatment and follow-up of patients with hydrocephalus. 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