TY  - JOUR
AU  - He, Qianyu
AU  - Zhang, Yuanxi
TI  - Kr-h1, a Cornerstone Gene in Insect Life History
JF  - FRONTIERS IN PHYSIOLOGY
J2  - FRONT PHYSIOL
VL  - 13
PY  - 2022
PG  - 14
SN  - 1664-042X
DO  - 10.3389/fphys.2022.905441
UR  - https://m2.mtmt.hu/api/publication/33842527
ID  - 33842527
AB  - Insect life cycle is coordinated by hormones and their downstream effectors. Kruppel homolog1 (Kr-h1) is one of the crucial effectors which mediates the actions of the two critical hormones of insects, the juvenile hormone (JH) and 20-hydroxyecdysone (20E). It is a transcription factor with a DNA-binding motif of eight C2H2 zinc fingers which is found to be conserved among insect orders. The expression of Kr-h1 is fluctuant during insect development with high abundance in juvenile instars and lower levels in the final instar and pupal stage, and reappearance in adults, which is governed by the coordination of JH, 20E, and miRNAs. The dynamic expression pattern of Kr-h1 is closely linked to its function in the entire life of insects. Over the past several years, accumulating studies have advanced our understanding of the role of Kr-h1 during insect development. It acts as a universal antimetamorphic factor in both hemimetabolous and holometabolous species by directly inhibiting the transcription of 20E signaling genes Broad-Complex (Br-C) and Ecdysone induced protein 93F (E93), and steroidogenic enzyme genes involved in ecdysone biosynthesis. Meanwhile, it promotes vitellogenesis and ovarian development in the majority of studied insects. In addition, Kr-h1 regulates insect behavioral plasticity and caste identity, neuronal morphogenesis, maturation of sexual behavior, as well as embryogenesis and metabolic homeostasis. Hence, Kr-h1 acts as a cornerstone regulator in insect life.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Sun, Ya-Ya
AU  - Fu, Dan-Yang
AU  - Liu, Bin
AU  - Wang, Lin-Jun
AU  - Chen, Hui
TI  - Roles of Kruppel Homolog 1 and Broad-Complex in the Development of Dendroctonus armandi (Coleoptera: Scolytinae)
JF  - FRONTIERS IN PHYSIOLOGY
J2  - FRONT PHYSIOL
VL  - 13
PY  - 2022
PG  - 16
SN  - 1664-042X
DO  - 10.3389/fphys.2022.865442
UR  - https://m2.mtmt.hu/api/publication/32934648
ID  - 32934648
AB  - In insects, metamorphosis is controlled by juvenile hormone (JH) and 20-hydroxyecdysone (20E). Kruppel homolog 1 (Kr-h1), a key JH-early inducible gene, is responsible for the suppression of metamorphosis and the regulation of the Broad-Complex (Br-C) gene, which is induced by 20E and functions as a "pupal specifier". In this study, we identified and characterized the expression patterns and tissue distribution of DaKr-h1 and DaBr-C at various developmental stages of Dendroctonus armandi. The expression of the two genes was induced by JH analog (JHA) methoprene and 20E, and their functions were investigated by RNA interference. DaKr-h1 and DaBr-C were predominantly expressed in the heads of larvae and were significantly downregulated during the molting stage. In contrast, the DaKr-h1 transcript level was highest in the adult anterior midgut. DaBr-C was mainly expressed in female adults, with the highest transcript levels in the ovaries. In the larval and pupal stages, both JHA and 20E significantly induced DaKr-h1, but only 20E significantly induced DaBr-C, indicating the importance of hormones in metamorphosis. DaKr-h1 knockdown in larvae upregulated DaBr-C expression, resulting in precocious metamorphosis from larvae to pupae and the formation of miniature pupae. DaKr-h1 knockdown in pupae suppressed DaBr-C expression, increased emergence, caused abnormal morphology, and caused the formation of small-winged adults. These results suggest that DaKr-h1 is required for the metamorphosis of D. armandi. Our findings provide insight into the roles of DaKr-h1 and DaBr-C in JH-induced transcriptional repression and highlight DaKr-h1 as a potential target for metamorphosis suppression in D. armandi.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Xu, Q-Y
AU  - Meng, Q-W
AU  - Deng, P.
AU  - Fu, K-Y
AU  - Guo, W-C
AU  - Li, G-Q
TI  - Impairment of pupation by RNA interference-aided knockdown of Broad-Complex gene in Leptinotarsa decemlineata (Say)
JF  - BULLETIN OF ENTOMOLOGICAL RESEARCH
J2  - B ENTOMOL RES
VL  - 109
PY  - 2019
IS  - 5
SP  - 659
EP  - 668
PG  - 10
SN  - 0007-4853
DO  - 10.1017/S0007485318001050
UR  - https://m2.mtmt.hu/api/publication/30902363
ID  - 30902363
AB  - Dietary delivery of bacterially expressed double-stranded RNA (dsRNA) has a great potential for management of Leptinotarsa decemlineata. An important first step is to discover possible RNA-interference (RNAi)-target genes effective against larvae, especially the old larvae. In the present paper, five putative Broad-Complex (BrC) cDNAs (Z1-Z4, and Z6) were identified in L. decemlineata. The expression of the five LdBrC isoforms was suppressed by juvenile hormone signaling, whereas the transcription was upregulated by 20-hydroxyecdysone signaling at the fourth (final) instar larval stage. Feeding of bacterially expressed dsBrC (derived from a common fragment of the five LdBrC variants) in the third- and fourth-instar larvae successfully knocked down the target mRNAs. For the fourth-instar LdBrC RNAi hypomorphs, they had a higher larval mortality compared with the controls. Moreover, most dsBrC-fed beetles did not pupate normally. After removal of the apolysed larval cuticle, a miniature adult was found. The adult head, compound eyes, prothorax, mesothorax, metathorax were found on the dorsal view. Distinct adult cuticle pigmentation was seen on the prothorax. The mouthparts, forelegs, midlegs, and hindlegs could be observed on the ventral view of the miniature adults. For the third-instar LdBrC RNAi specimens, around 20% moribund beetles remained as prepupae and finally died. Therefore, LdBrC is among the most attractive candidate genes for RNAi to control the fourth-instar larvae in L. decemlineata.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Xu, Q. -Y.
AU  - Meng, Q. -W.
AU  - Deng, P.
AU  - Fu, K. -Y.
AU  - Guo, W. -C.
AU  - Li, G. -Q.
TI  - Isoform specific roles of Broad-Complex in larval development in Leptinotarsa decemlineata
JF  - INSECT MOLECULAR BIOLOGY
J2  - INSECT MOL BIOL
VL  - 28
PY  - 2019
IS  - 3
SP  - 420
EP  - 430
PG  - 11
SN  - 0962-1075
DO  - 10.1111/imb.12563
UR  - https://m2.mtmt.hu/api/publication/30902364
ID  - 30902364
AB  - Broad-Complex (BrC) is a downstream target of both 20-hydroxyecdysone and juvenile hormone signalling. BrC regulates morphogenetic changes between nymphal instars in hemimetabolans, whereas it controls pupal commitment, pupal morphogenesis and inhibits adult differentiation in holometabolans. Among five BrC cDNAs (Z1-Z4 and Z6) identified in the Colorado potato beetle, we found in this work that Z1, Z2 and Z6 were mainly expressed at the last (fourth) instar and prepupal stages, whereas the levels of Z3 and Z4 increased during the penultimate (third) instar stage, peaked at the last instar larval phase and gradually decreased at the prepupal and pupal periods. When knocking down all BrC isoforms by RNA interference (RNAi) at the penultimate instar stage, around 20% of the resultant larvae remained as moribund beetles. These moribund BrC RNAi larvae were completely or partially wrapped in old cuticle. Likewise, a portion of larvae treated for a single double-stranded RNA of Z3, Z4 or Z6 displayed a degree of similar aberrancies, increasing in the order of isoforms Z6 BrC isoforms at the last instar period, most of the RNAi larvae did not normally pupate or emerge as adults. Separately silencing each of the five zinc finger domains revealed that approximately 70% of the Z1 RNAi larvae remained as prepupae, around 60% of the Z6 RNAi specimens formed aberrant prepupae or pupae and about 60% of the Z2 RNAi beetles became deformed pupae. After removal of the old exuviae, these deformed larvae in which either Z1, Z2 or Z6 was depleted possessed adult prothorax and mesothorax, developing antenna, mouthparts and wing discs. Moreover, less than 50% of the resultant pupae finally emerged as adults when either of Z1, Z2 or Z6 was knocked down. Therefore, our findings reveal, for the first time, that the two roles of BrC in insect groups (ie directing morphogenetic changes during juvenile development and regulating larval-pupal-adult metamorphosis) are played by different BrC isoforms in Leptinotarsa decemlineata.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Miyakawa, Hitoshi
AU  - Sato, Tomomi
AU  - Song, You
AU  - Tollefsen, Knut Erik
AU  - Iguchi, Taisen
TI  - Ecdysteroid and juvenile hormone biosynthesis, receptors and their signaling in the freshwater microcrustacean Daphnia
JF  - JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
J2  - J STEROID BIOCHEM MOL BIOL
VL  - 184
PY  - 2018
SP  - 62
EP  - 68
PG  - 7
SN  - 0960-0760
DO  - 10.1016/j.jsbmb.2017.12.006
UR  - https://m2.mtmt.hu/api/publication/30465803
ID  - 30465803
AB  - The two essential insect hormones, ecdysteroids and juvenile hormones, are possessed not only by insects, but also widely by arthropods, and regulate various developmental and physiological processes. In contrast to the abundant information about molecular endocrine mechanisms in insects, the knowledge of non-insect arthropod endocrinology is still limited. In this review, we summarize recent reports about the molecular basis of these to major insect hormones in the freshwater microcrustacean Daphnia, a keystone taxon in limnetic ecology and bioindicator in environmental studies. Comprehensive comparisons of endocrine signaling pathways between insects and daphnids may shed light on the regulatory mechanisms of various biological phenomena an, moreover, evolutionary processes of arthropod species.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Kayukawa, Takumi
AU  - Jouraku, Akiya
AU  - Ito, Yuka
AU  - Shinoda, Tetsuro
TI  - Molecular mechanism underlying juvenile hormone-mediated repression of precocious larval-adult metamorphosis
JF  - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
J2  - P NATL ACAD SCI USA
VL  - 114
PY  - 2017
IS  - 5
SP  - 1057
EP  - 1062
PG  - 6
SN  - 0027-8424
DO  - 10.1073/pnas.1615423114
UR  - https://m2.mtmt.hu/api/publication/26537160
ID  - 26537160
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Kayukawa, Takumi
AU  - Nagamine, Keisuke
AU  - Ito, Yuka
AU  - Nishita, Yoshinori
AU  - Ishikawa, Yukio
AU  - Shinoda, Tetsuro
TI  - Kruppel Homolog 1 Inhibits Insect Metamorphosis via Direct Transcriptional Repression of Broad-Complex, a Pupal Specifier Gene
JF  - JOURNAL OF BIOLOGICAL CHEMISTRY
J2  - J BIOL CHEM
VL  - 291
PY  - 2016
IS  - 4
SP  - 1751
EP  - 1762
PG  - 12
SN  - 0021-9258
DO  - 10.1074/jbc.M115.686121
UR  - https://m2.mtmt.hu/api/publication/26183633
ID  - 26183633
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Vea, Isabelle Mifom
AU  - Tanaka, Sayumi
AU  - Shiotsuki, Takahiro
AU  - Jouraku, Akiya
AU  - Tanaka, Toshiharu
AU  - Minakuchi, Chieka
TI  - Differential Juvenile Hormone Variations in Scale Insect Extreme Sexual Dimorphism
JF  - PLOS ONE
J2  - PLOS ONE
VL  - 11
PY  - 2016
IS  - 2
PG  - 18
SN  - 1932-6203
DO  - 10.1371/journal.pone.0149459
UR  - https://m2.mtmt.hu/api/publication/26183632
ID  - 26183632
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Jiang, S F
AU  - Zhang, Y P
AU  - Sun, S M
AU  - Gong, Y S
AU  - Xiong, Y W
AU  - Qiao, H
AU  - Zhang, W Y
AU  - Jin, S B
AU  - Fu, H T
TI  - Molecular cloning, characterization, and expression analysis of a Broad-Complex homolog during development in the oriental river prawn Macrobrachium nipponense
JF  - GENETICS AND MOLECULAR RESEARCH
J2  - GENET MOL RES
VL  - 14
PY  - 2015
IS  - 2
SP  - 5141
EP  - 5152
PG  - 12
SN  - 1676-5680
DO  - 10.4238/2015.May.18.4
UR  - https://m2.mtmt.hu/api/publication/26183634
ID  - 26183634
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Huang, YC
AU  - Lu, YN
AU  - Wu, JT
AU  - Chien, CT
AU  - Pi, HW
TI  - The COP9 Signalosome Converts Temporal Hormone Signaling to Spatial Restriction on Neural Competence
JF  - PLOS GENETICS
J2  - PLOS GENET
VL  - 10
PY  - 2014
IS  - 11
PG  - 13
SN  - 1553-7390
DO  - 10.1371/journal.pgen.1004760
UR  - https://m2.mtmt.hu/api/publication/24722126
ID  - 24722126
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Latha, RS
AU  - Vijayaraj, R
AU  - Padmanabhan, J
AU  - Singam, ERA
AU  - Chitra, K
AU  - Subramanian, V
TI  - 3D-QSAR studies on the biological activity of juvenile hormone mimetic compounds for Culex pipiens Larvae
JF  - MEDICINAL CHEMISTRY RESEARCH
J2  - MED CHEM RES
VL  - 22
PY  - 2013
IS  - 12
SP  - 5948
EP  - 5960
PG  - 13
SN  - 1054-2523
DO  - 10.1007/s00044-013-0585-5
UR  - https://m2.mtmt.hu/api/publication/24090913
ID  - 24090913
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Liew, GM
AU  - Foulk, MS
AU  - Gerbi, SA
TI  - The ecdysone receptor (ScEcR-A) binds DNA puffs at the start of DNA amplification in Sciara coprophila
JF  - CHROMOSOME RESEARCH
J2  - CHROMOSOME RES
VL  - 21
PY  - 2013
IS  - 4
SP  - 345
EP  - 360
PG  - 16
SN  - 0967-3849
DO  - 10.1007/s10577-013-9360-1
UR  - https://m2.mtmt.hu/api/publication/24090912
ID  - 24090912
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Abdou, MA
AU  - He, QY
AU  - Wen, D
AU  - Zyaan, O
AU  - Wang, J
AU  - Xu, JJ
AU  - Baumann, AA
AU  - Joseph, J
AU  - Wilson, TG
AU  - Li, S
AU  - Wang, J
TI  - Drosophila Met and Gce are partially redundant in transducing juvenile hormone action
JF  - INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
J2  - INSECT BIOCHEM MOLEC
VL  - 41
PY  - 2011
IS  - 12
SP  - 938
EP  - 945
PG  - 8
SN  - 0965-1748
DO  - 10.1016/j.ibmb.2011.09.003
UR  - https://m2.mtmt.hu/api/publication/22104027
ID  - 22104027
N1  - Z9: 1
DI: 10.1016/j.ibmb.2011.09.003
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Minakuchi, C
AU  - Tanaka, M
AU  - Miura, K
AU  - Tanaka, T
TI  - Developmental profile and hormonal regulation of the transcription factors broad and Kruppel homolog 1 in hemimetabolous thrips.
JF  - INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
J2  - INSECT BIOCHEM MOLEC
VL  - 41
PY  - 2011
IS  - 2
SP  - 125
EP  - 134
PG  - 10
SN  - 0965-1748
DO  - 10.1016/j.ibmb.2010.11.004
UR  - https://m2.mtmt.hu/api/publication/21983909
ID  - 21983909
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Zhou, B H
AU  - Williams, D W
AU  - Altman, J
AU  - Riddiford, L M
AU  - Truman, J W
TI  - Temporal patterns of broad isoform expression during the development of neuronal lineages in Drosophila
JF  - NEURAL DEVELOPMENT
J2  - NEURAL DEV
VL  - 4
PY  - 2009
SN  - 1749-8104
DO  - 10.1186/1749-8104-4-39
UR  - https://m2.mtmt.hu/api/publication/21983458
ID  - 21983458
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Minakuchi, C
AU  - Zhou, X
AU  - Riddiford, LM
TI  - Kruppel homolog 1 (Kr-h1) mediates juvenile hormone action during metamorphosis of Drosophila melanogaster
JF  - MECHANISMS OF DEVELOPMENT
J2  - MECH DEVELOP
VL  - 125
PY  - 2008
IS  - 1-2
SP  - 91
EP  - 105
PG  - 15
SN  - 0925-4773
DO  - 10.1016/j.mod.2007.10.002
UR  - https://m2.mtmt.hu/api/publication/22104041
ID  - 22104041
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Muramatsu, D
AU  - Kinjoh, T
AU  - Shinoda, T
AU  - Hiruma, K
TI  - The role of 20-hydroxyecdysone and juvenile hormone in pupal commitment of the epidermis of the silkworm, Bombyx mori
JF  - MECHANISMS OF DEVELOPMENT
J2  - MECH DEVELOP
VL  - 125
PY  - 2008
IS  - 5-6
SP  - 411
EP  - 420
PG  - 10
SN  - 0925-4773
DO  - 10.1016/j.mod.2008.02.001
UR  - https://m2.mtmt.hu/api/publication/22104040
ID  - 22104040
N1  - DI: 10.1016/j.mod.2008.02.001
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Parthasarathy, R
AU  - Tan, A
AU  - Bai, H
AU  - Palli, SR
TI  - Transcription factor broad suppresses precocious development of adult structures during larval-pupal metamorphosis in the red flour beetle, Tribolium castaneum
JF  - MECHANISMS OF DEVELOPMENT
J2  - MECH DEVELOP
VL  - 125
PY  - 2008
IS  - 3-4
SP  - 299
EP  - 313
PG  - 15
SN  - 0925-4773
DO  - 10.1016/j.mod.2007.11.001
UR  - https://m2.mtmt.hu/api/publication/24519438
ID  - 24519438
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Basso, LR
AU  - Neves, MD
AU  - Monesi, N
AU  - Paco-Larson, ML
TI  - Broad-Complex, E74, and E75 early genes control DNA puff BhC4-1 expression in prepupal salivary glands
JF  - GENESIS: THE JOURNAL OF GENETICS AND DEVELOPMENT
J2  - GENESIS
VL  - 44
PY  - 2006
IS  - 11
SP  - 505
EP  - 514
PG  - 10
SN  - 1526-954X
DO  - 10.1002/dvg.20239
UR  - https://m2.mtmt.hu/api/publication/23389046
ID  - 23389046
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Erezyilmaz, D F
TI  - Imperfect eggs and oviform nymphs: a history of ideas about the origins of insect metamorphosis
JF  - INTEGRATIVE AND COMPARATIVE BIOLOGY
J2  - INTEGR COMP BIOL
VL  - 46
PY  - 2006
SP  - 795
EP  - 807
PG  - 13
SN  - 1540-7063
DO  - 10.1093/icb/icl033
UR  - https://m2.mtmt.hu/api/publication/22068802
ID  - 22068802
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Erezyilmaz, D F
AU  - Riddiford, L M
AU  - Truman, J W
TI  - The pupal specifier broad directs progressive morphogenesis in a direct-developing insect
JF  - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
J2  - P NATL ACAD SCI USA
VL  - 103
PY  - 2006
IS  - 18
SP  - 6925
EP  - 6930
PG  - 6
SN  - 0027-8424
DO  - 10.1073/pnas.0509983103
UR  - https://m2.mtmt.hu/api/publication/21979292
ID  - 21979292
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Nishita, Y
AU  - Takiya, S
TI  - Differential usage of two promoters of the Broad-Complex gene in the silkworm, Bombyx mori
JF  - INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
J2  - INSECT BIOCHEM MOLEC
VL  - 36
PY  - 2006
IS  - 10
SP  - 779
EP  - 788
PG  - 10
SN  - 0965-1748
DO  - 10.1016/j.ibmb.2006.07.005
UR  - https://m2.mtmt.hu/api/publication/21982686
ID  - 21982686
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Ward, EJ
AU  - Zhou, XF
AU  - Riddiford, LM
AU  - Berg, CA
AU  - Ruohola-Baker, H
TI  - Border of Notch activity establishes a boundary between the two dorsal appendage tube cell types
JF  - DEVELOPMENTAL BIOLOGY
J2  - DEV BIOL
VL  - 297
PY  - 2006
IS  - 2
SP  - 461
EP  - 470
PG  - 10
SN  - 0012-1606
DO  - 10.1016/j.ydbio.2006.05.021
UR  - https://m2.mtmt.hu/api/publication/22225497
ID  - 22225497
N1  - DI: 10.1016/j.ydbio.2006.05.021
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Reza, Ams
AU  - Kanamori, Y
AU  - Shinoda, T
AU  - Shimura, S
AU  - Mita, K
AU  - Nakahara, Y
AU  - Kiuchi, M
AU  - Kamimura, M
TI  - Hormonal control of a metamorphosis-specific transcriptional factor Broad-Complex in silkworm
JF  - COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
J2  - COMP BIOCHEM PHYS B
VL  - 139
PY  - 2004
SP  - 753
EP  - 761
PG  - 9
SN  - 1096-4959
DO  - 10.1016/j.cbpc.2004.09.009
UR  - https://m2.mtmt.hu/api/publication/22104063
ID  - 22104063
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Zhou, XF
AU  - Zhou, BH
AU  - Truman, JW
AU  - Riddiford, LM
TI  - Overexpression of broad: a new insight into its role in the Drosophila prothoracic gland cells
JF  - JOURNAL OF EXPERIMENTAL BIOLOGY
J2  - J EXP BIOL
VL  - 207
PY  - 2004
SP  - 1151
EP  - 1161
PG  - 11
SN  - 0022-0949
DO  - 10.1242/jeb.00855
UR  - https://m2.mtmt.hu/api/publication/22104061
ID  - 22104061
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Bayer, C
AU  - Zhou, XF
AU  - Zhou, BH
AU  - Riddiford, LM
AU  - von Kalm, L
TI  - Evolution of the Drosophila broad locus: the Manduca sexta broad Z4 isoform has biological activity in Drosophila
JF  - DEVELOPMENT GENES AND EVOLUTION
J2  - DEV GENES EVOL
VL  - 213
PY  - 2003
SP  - 471
EP  - 476
PG  - 6
SN  - 0949-944X
DO  - 10.1007/s00427-003-0354-4
UR  - https://m2.mtmt.hu/api/publication/22104070
ID  - 22104070
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Zhou, XF
AU  - Riddiford, LM
TI  - Broad specifies pupal development and mediates the 'status quo' action of juvenile hormone on the pupal-adult transformation in Drosophila and Manduca
JF  - DEVELOPMENT
J2  - DEVELOPMENT
VL  - 129
PY  - 2002
SP  - 2259
EP  - 2269
PG  - 11
SN  - 0950-1991
UR  - https://m2.mtmt.hu/api/publication/22104080
ID  - 22104080
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Dubrovsky, E B
AU  - Dubrovskaya, V A
AU  - Berger, E M
TI  - Selective binding of Drosophila BR-C isoforms to a distal regulatory element in the hsp23 promoter
JF  - INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
J2  - INSECT BIOCHEM MOLEC
VL  - 31
PY  - 2001
IS  - 12
SP  - 1231
EP  - 1239
PG  - 9
SN  - 0965-1748
DO  - 10.1016/S0965-1748(01)00071-6
UR  - https://m2.mtmt.hu/api/publication/21979230
ID  - 21979230
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Mugat, B
AU  - Brodu, V
AU  - Kejzlarovalepes, null
AU  - Antoniewski, C
AU  - Bayer, CA
AU  - Fristrom, JW
AU  - Lepesant, JA
TI  - Dynamic Expression of Broad-Complex Isoforms Mediates Temporal Control of an Ecdysteroid Target Gene at the Onset of Drosophila Metamorphosis.
JF  - DEVELOPMENTAL BIOLOGY
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TY  - JOUR
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ID  - 22554941
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Dubrovsky, EB
AU  - Dretzen, G
AU  - Berger, EM
TI  - The Broad-Complex Gene Is a Tissue-Specific Modulator of the Ecdysone Response of the Drosophila Hsp23 Gene.
JF  - MOLECULAR AND CELLULAR BIOLOGY
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DB  - MTMT
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TY  - JOUR
AU  - Fletcher, JC
AU  - Thummel, CS
TI  - The Ecdysone-Inducible Broad-Complex and E74 Early Genes Interact to Regulate Target Gene-Transcription and Drosophila Metamorphosis.
JF  - GENETICS
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TY  - JOUR
AU  - Vonkalm, L
AU  - Fristrom, D
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TI  - The Making of a Fly Leg - A Model for Epithelial Morphogenesis.
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ER  - 

TY  - JOUR
AU  - Zhimulev, IF
AU  - Belyaeva, ES
AU  - Semeshin, VF
AU  - Pokholkova, GV
AU  - Kokoza, EB
AU  - Kozlova, TY
AU  - Demakov, SA
AU  - Malceva, NI
AU  - Demakova, OV
AU  - Balasov, ML
AU  - Koryakov, DE
AU  - Makunin, IV
AU  - Belousova, NV
TI  - Molecular Cytogenetic Organization of Polytene Chromosomes.
JF  - RUSSIAN CHEMICAL BULLETIN
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TY  - JOUR
AU  - Segraves, WA
TI  - Steroid-Receptors and Other Transcription Factors in Ecdysone Response.
JF  - RECENT PROGRESS IN HORMONE RESEARCH
J2  - RECENT PROG HORM RES
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N1  - Megjegyzés-20786442
SE: RECENT PROGRESS IN HORMONE RESEARCH
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Karim, FD
AU  - Guild, GM
AU  - Thummel, CS
TI  - The Drosophila Broad-Complex Plays a Key Role in Controlling Ecdysone-Regulated Gene-Expression at the Onset of Metamorphosis.
JF  - DEVELOPMENT
J2  - DEVELOPMENT
VL  - 118
PY  - 1993
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DB  - MTMT
ER  - 

TY  - JOUR
AU  - Segal, D
TI  - PROSPECTS OF USING DROSOPHILA FOR INSECT NEUROENDOCRINE RESEARCH
JF  - ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY
J2  - ARCH INSECT BIOCHEM
VL  - 22
PY  - 1993
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SP  - 199
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ID  - 21983037
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Restifo, LL
AU  - White, K
TI  - Mutations in a Steroid Hormone-Regulated Gene Disrupt the Metamorphosis of Internal Tissues in Drosophila - Salivary- Glands, Muscle, and Gut.
JF  - ROUXS ARCHIVES OF DEVELOPMENTAL BIOLOGY
J2  - ROUX ARCH DEV BIOL
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PY  - 1992
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DB  - MTMT
ER  - 

TY  - JOUR
AU  - RESTIFO, LL
AU  - WHITE, K
TI  - MUTATIONS IN A STEROID HORMONE-REGULATED GENE DISRUPT THE METAMORPHOSIS OF INTERNAL TISSUES IN DROSOPHILA - SALIVARY-GLANDS, MUSCLE, AND GUT
JF  - ROUXS ARCHIVES OF DEVELOPMENTAL BIOLOGY
J2  - ROUX ARCH DEV BIOL
VL  - 201
PY  - 1992
IS  - 4
SP  - 221
EP  - 234
PG  - 14
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DB  - MTMT
ER  - 

TY  - JOUR
AU  - Dibello, PR
AU  - Withers, DA
AU  - Bayer, CA
AU  - Fristrom, JW
AU  - Guild, GM
TI  - The Drosophila Broad-Complex Encodes a Family of Related Proteins Containing Zinc Fingers.
JF  - GENETICS
J2  - GENETICS
VL  - 129
PY  - 1991
SP  - 385
EP  - 397
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ID  - 22104159
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Mazina, OM
AU  - Belyaeva, ES
AU  - Zhimulev, IF
TI  - CYTOGENETICAL ANALYSIS OF THE 2B3-4-2B11 REGION OF THE X-CHROMOSOME OF DROSOPHILA-MELANOGASTER .7. INFLUENCE OF THE ECS LOCUS ON FEMALE FERTILITY
JF  - MOLECULAR & GENERAL GENETICS
J2  - MOL GEN GENET
VL  - 225
PY  - 1991
SP  - 99
EP  - 105
PG  - 7
SN  - 0026-8925
UR  - https://m2.mtmt.hu/api/publication/22064730
ID  - 22064730
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Mazina, OM
AU  - Korochkina, SE
TI  - Studies on the Nature of Female-Sterile Mutations at the Ecs Locus Responsible for Sensitivity to Ecdysterone in Drosophila-Melanogaster.
VL  - 27
PY  - 1991
SP  - 1920
EP  - 1927
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ER  - 

TY  - JOUR
AU  - MAZINA, OM
AU  - KOROCHKINA, SE
TI  - STUDIES ON THE NATURE OF FEMALE-STERILE MUTATIONS AT THE ECS LOCUS RESPONSIBLE FOR SENSITIVITY TO ECDYSTERONE IN DROSOPHILA-MELANOGASTER
JF  - GENETIKA
J2  - GENETIKA
VL  - 27
PY  - 1991
IS  - 11
SP  - 1920
EP  - 1927
PG  - 8
SN  - 0016-6758
UR  - https://m2.mtmt.hu/api/publication/23406505
ID  - 23406505
LA  - Russian
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Restifo, LL
AU  - White, K
TI  - Mutations in a Steroid Hormone-Regulated Gene Disrupt the Metamorphosis of the Central-Nervous-System in Drosophila.
JF  - DEVELOPMENTAL BIOLOGY
J2  - DEV BIOL
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PY  - 1991
SP  - 174
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SN  - 0012-1606
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ID  - 22104161
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Galceran, J
AU  - Llanos, J
AU  - Sampedro, J
AU  - Pongs, O
AU  - Izquierdo, M
TI  - TRANSCRIPTION AT THE ECDYSONE-INDUCIBLE LOCUS-2B5 IN DROSOPHILA
JF  - NUCLEIC ACIDS RESEARCH
J2  - NUCLEIC ACIDS RES
VL  - 18
PY  - 1990
IS  - 3
SP  - 539
EP  - 545
PG  - 7
SN  - 0305-1048
DO  - 10.1093/nar/18.3.539
UR  - https://m2.mtmt.hu/api/publication/21979617
ID  - 21979617
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Mazina, OM
AU  - Belyaeva, ES
AU  - Graphodatskaya, VE
AU  - Zhimulev, IF
TI  - INFLUENCE OF THE DROSOPHILA-MELANOGASTER ECS LOCUS ON FEMALE FERTILITY
JF  - GENETIKA
J2  - GENETIKA
VL  - 26
PY  - 1990
SP  - 1038
EP  - 1045
PG  - 8
SN  - 0016-6758
UR  - https://m2.mtmt.hu/api/publication/22064731
ID  - 22064731
LA  - Russian
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Sampedro, J
AU  - Izquierdo, M
AU  - Galceran, J
TI  - Mutation Mapping of the 2B5 Ecdysone Locus in Drosophila-Melanogaster Reveals a Long-Distance Controlling Element.
JF  - MOLECULAR AND CELLULAR BIOLOGY
J2  - MOL CELL BIOL
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PY  - 1989
SP  - 3588
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DB  - MTMT
ER  - 

TY  - JOUR
AU  - Kiss, István
AU  - BEATON, AH
AU  - TARDIFF, J
AU  - FRISTROM, D
AU  - FRISTROM, JW
TI  - Interactions and developmental effects of mutations at the 2B5 locus of Drosophila melanogaster.
JF  - GENETICS
J2  - GENETICS
VL  - 118
PY  - 1988
SP  - 247
EP  - 259
PG  - 13
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UR  - https://m2.mtmt.hu/api/publication/1904570
ID  - 1904570
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Protopopov, MO
AU  - Belyaeva, ES
AU  - Kokoza, EB
AU  - Sharapova, EM
AU  - Baricheva, EM
AU  - Demakova, OV
AU  - Grafodatskaya, VE
AU  - Zhimulev, IF
TI  - CYTOGENETIC ANALYSIS OF 2B1-2-2B9-10 OF THE X-CHROMOSOME OF DROSOPHILA MELANOGASTER .7. CLONING OF THE ECS, DOR AND SWI LOCI
JF  - GENETIKA
J2  - GENETIKA
VL  - 24
PY  - 1988
SP  - 1614
EP  - 1623
PG  - 10
SN  - 0016-6758
UR  - https://m2.mtmt.hu/api/publication/22064734
ID  - 22064734
LA  - Russian
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Raghavan, KV
AU  - Meyerowitz, EM
AU  - Mayeda, C
TI  - The Action of the L(1)NPR-1+ Locus on the Drosophila Glue Gene Sgs-3 Is Cell-Autonomous.
JF  - JOURNAL OF GENETICS
J2  - J GENET
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PY  - 1988
SP  - 141
EP  - 150
PG  - 10
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DO  - 10.1007/BF02927825
UR  - https://m2.mtmt.hu/api/publication/22068835
ID  - 22068835
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Belyaeva, ES
AU  - Protopopov, MO
AU  - Baricheva, EM
AU  - Semeshin, VF
AU  - Izquierdo, ML
AU  - Zhimulev, IF
TI  - CYTOGENETIC ANALYSIS OF REGION 2B3-4-2B11 OF THE X-CHROMOSOME OF DROSOPHILA-MELANOGASTER .6. MOLECULAR AND CYTOLOGICAL MAPPING OF THE ECS LOCUS AND THE 2B PUFF
JF  - CHROMOSOMA
J2  - CHROMOSOMA
VL  - 95
PY  - 1987
SP  - 295
EP  - 310
PG  - 16
SN  - 0009-5915
DO  - 10.1007/BF00294787
UR  - https://m2.mtmt.hu/api/publication/22137721
ID  - 22137721
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Szabad, János
AU  - BRYANT, PJ
TI  - The mode of action of "discless" mutations in Drosophila melanogaster.
JF  - DEVELOPMENTAL BIOLOGY
J2  - DEV BIOL
VL  - 93
PY  - 1982
SP  - 240
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DO  - 10.1016/0012-1606(82)90256-1
UR  - https://m2.mtmt.hu/api/publication/1899417
ID  - 1899417
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Zhimulev, I F
AU  - Vlassova, I E
AU  - Belyaeva, E S
TI  - CYTOGENETIC ANALYSIS OF THE 2B3-4-2B11 REGION OF THE X-CHROMOSOME OF DROSOPHILA-MELANOGASTER .3. PUFFING DISTURBANCE IN SALIVARY-GLAND CHROMOSOMES OF HOMOZYGOTES FOR MUTATION L(1)PPLT10
JF  - CHROMOSOMA
J2  - CHROMOSOMA
VL  - 85
PY  - 1982
IS  - 5
SP  - 569
EP  - 672
PG  - 104
SN  - 0009-5915
DO  - 10.1007/BF00330779
UR  - https://m2.mtmt.hu/api/publication/21983434
ID  - 21983434
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Belyaeva, ES
AU  - Vlassova, IE
AU  - Biyasheva, ZM
AU  - Kakpakov, VT
AU  - Richards, G
AU  - Zhimulev, IF
TI  - CYTOGENETIC ANALYSIS OF THE 2B3-4-2B11 REGION OF THE X- CHROMOSOME OF DROSOPHILA-MELANOGASTER .2. CHANGES IN 20-OH ECDYSONE PUFFING CAUSED BY GENETIC-DEFECTS OF PUFF-2B5
JF  - CHROMOSOMA
J2  - CHROMOSOMA
VL  - 84
PY  - 1981
SP  - 207
EP  - 219
PG  - 13
SN  - 0009-5915
DO  - 10.1007/BF00399132
UR  - https://m2.mtmt.hu/api/publication/22137724
ID  - 22137724
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Biiasheva, ZM
AU  - Zhimulev, IF
AU  - Kakpakov, VT
AU  - Richards, G
AU  - Aizenzon, MG
AU  - Beliaeva, ES
TI  - 2 CLOSELY LINKED LOCI CONTROLLING ECDYSONE-DEPENDENT PUFFING IN DROSOPHILA-MELANOGASTER
JF  - DOKLADY AKADEMII NAUK SSSR
J2  - DOKL AKAD NAUK SSSR
VL  - 256
PY  - 1981
SP  - 983
SN  - 0002-3264
UR  - https://m2.mtmt.hu/api/publication/22064737
ID  - 22064737
LA  - Russian
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Fristrom, DK
AU  - Fekete, Éva
AU  - Fristrom, JW
TI  - Imaginal disc development in a non-pupariating lethal mutant in Drosophila melanogaster
JF  - WILHELM ROUX S ARCHIVES OF DEVELOPMENTAL BIOLOGY
J2  - WILH ROUX S ARC DEV BIOL
VL  - 190
PY  - 1981
IS  - 1
SP  - 11
EP  - 21
PG  - 11
SN  - 0340-0794
UR  - https://m2.mtmt.hu/api/publication/2840272
ID  - 2840272
N1  - 
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Ashburner, M
TI  - CHROMOSOMAL ACTION OF ECDYSONE
JF  - NATURE
J2  - NATURE
VL  - 285
PY  - 1980
SP  - 435
EP  - 436
PG  - 2
SN  - 0028-0836
DO  - 10.1038/285435a0
UR  - https://m2.mtmt.hu/api/publication/22137502
ID  - 22137502
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - BELYAEVA, ES
AU  - AIZENZON, MG
AU  - SEMESHIN, VF
AU  - Kiss, István
AU  - Koczka, Katalin
AU  - BARITCHEVA, EM
AU  - GOREM, D
AU  - ZHIMULEV, IF
TI  - Cytogenetic analysis of the 2B3-4-2B11 region of the X chromosome of Drosophila melanogaster. I. Cytology of the region and mutant complementation groups.
JF  - CHROMOSOMA
J2  - CHROMOSOMA
VL  - 81
PY  - 1980
SP  - 281
EP  - 306
PG  - 26
SN  - 0009-5915
DO  - 10.1007/BF00285954
UR  - https://m2.mtmt.hu/api/publication/1899746
ID  - 1899746
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Zhimulev, IF
AU  - Belyaeva, ES
AU  - Aizenzon, MG
TI  - CYTOGENETIC ANALYSIS OF THE DROSOPHILA-MELANOGASTER X-CHROMOSOME REGION 2B1-2-2B9-10 .3. CHANGES OF PUFFING PATTERNS IN SALIVARY-GLAND CHROMOSOMES OF LARVAE HOMOZYGOUS FOR MUTATION 1(1)PP-T10
JF  - GENETIKA
J2  - GENETIKA
VL  - 16
PY  - 1980
SP  - 1613
EP  - 1631
PG  - 19
SN  - 0016-6758
UR  - https://m2.mtmt.hu/api/publication/22064739
ID  - 22064739
LA  - Russian
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Kiss, István
AU  - Szabad, János
AU  - Major, J.
TI  - Genetic and developmental analysis of puparium formation in Drosophila.
JF  - MOLECULAR & GENERAL GENETICS
J2  - MOL GEN GENET
VL  - 164
PY  - 1978
IS  - 1
SP  - 77
EP  - 83
PG  - 7
SN  - 0026-8925
DO  - 10.1007/BF00267601
UR  - https://m2.mtmt.hu/api/publication/1900772
ID  - 1900772
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Murphy, C
AU  - Fristrom, J W
AU  - Shearn, A
TI  - ASPECTS OF DEVELOPMENT OF IMAGINAL DISKS IN A NON-PUPARIATING LETHAL MUTANT IN DROSOPHILA-MELANOGASTER
JF  - CELL DIFFERENTIATION
J2  - CELL DIFFER
VL  - 6
PY  - 1977
IS  - 5-6
SP  - 319
EP  - 330
PG  - 12
SN  - 0045-6039
DO  - 10.1016/0045-6039(77)90007-0
UR  - https://m2.mtmt.hu/api/publication/21982681
ID  - 21982681
LA  - English
DB  - MTMT
ER  -