@article{MTMT:33842527,
	title = {Kr-h1, a Cornerstone Gene in Insect Life History},
	url = {https://m2.mtmt.hu/api/publication/33842527},
	author = {He, Qianyu and Zhang, Yuanxi},
	doi = {10.3389/fphys.2022.905441},
	journal-iso = {FRONT PHYSIOL},
	journal = {FRONTIERS IN PHYSIOLOGY},
	volume = {13},
	unique-id = {33842527},
	abstract = {Insect life cycle is coordinated by hormones and their downstream effectors. Kruppel homolog1 (Kr-h1) is one of the crucial effectors which mediates the actions of the two critical hormones of insects, the juvenile hormone (JH) and 20-hydroxyecdysone (20E). It is a transcription factor with a DNA-binding motif of eight C2H2 zinc fingers which is found to be conserved among insect orders. The expression of Kr-h1 is fluctuant during insect development with high abundance in juvenile instars and lower levels in the final instar and pupal stage, and reappearance in adults, which is governed by the coordination of JH, 20E, and miRNAs. The dynamic expression pattern of Kr-h1 is closely linked to its function in the entire life of insects. Over the past several years, accumulating studies have advanced our understanding of the role of Kr-h1 during insect development. It acts as a universal antimetamorphic factor in both hemimetabolous and holometabolous species by directly inhibiting the transcription of 20E signaling genes Broad-Complex (Br-C) and Ecdysone induced protein 93F (E93), and steroidogenic enzyme genes involved in ecdysone biosynthesis. Meanwhile, it promotes vitellogenesis and ovarian development in the majority of studied insects. In addition, Kr-h1 regulates insect behavioral plasticity and caste identity, neuronal morphogenesis, maturation of sexual behavior, as well as embryogenesis and metabolic homeostasis. Hence, Kr-h1 acts as a cornerstone regulator in insect life.},
	keywords = {reproduction; ecdysone; metamorphosis; EMBRYOGENESIS; Juvenile hormone; Kr-h1; neuronal morphogenesis; behavioral plastisity},
	year = {2022},
	eissn = {1664-042X}
}

@article{MTMT:32934648,
	title = {Roles of Kruppel Homolog 1 and Broad-Complex in the Development of Dendroctonus armandi (Coleoptera: Scolytinae)},
	url = {https://m2.mtmt.hu/api/publication/32934648},
	author = {Sun, Ya-Ya and Fu, Dan-Yang and Liu, Bin and Wang, Lin-Jun and Chen, Hui},
	doi = {10.3389/fphys.2022.865442},
	journal-iso = {FRONT PHYSIOL},
	journal = {FRONTIERS IN PHYSIOLOGY},
	volume = {13},
	unique-id = {32934648},
	abstract = {In insects, metamorphosis is controlled by juvenile hormone (JH) and 20-hydroxyecdysone (20E). Kruppel homolog 1 (Kr-h1), a key JH-early inducible gene, is responsible for the suppression of metamorphosis and the regulation of the Broad-Complex (Br-C) gene, which is induced by 20E and functions as a "pupal specifier". In this study, we identified and characterized the expression patterns and tissue distribution of DaKr-h1 and DaBr-C at various developmental stages of Dendroctonus armandi. The expression of the two genes was induced by JH analog (JHA) methoprene and 20E, and their functions were investigated by RNA interference. DaKr-h1 and DaBr-C were predominantly expressed in the heads of larvae and were significantly downregulated during the molting stage. In contrast, the DaKr-h1 transcript level was highest in the adult anterior midgut. DaBr-C was mainly expressed in female adults, with the highest transcript levels in the ovaries. In the larval and pupal stages, both JHA and 20E significantly induced DaKr-h1, but only 20E significantly induced DaBr-C, indicating the importance of hormones in metamorphosis. DaKr-h1 knockdown in larvae upregulated DaBr-C expression, resulting in precocious metamorphosis from larvae to pupae and the formation of miniature pupae. DaKr-h1 knockdown in pupae suppressed DaBr-C expression, increased emergence, caused abnormal morphology, and caused the formation of small-winged adults. These results suggest that DaKr-h1 is required for the metamorphosis of D. armandi. Our findings provide insight into the roles of DaKr-h1 and DaBr-C in JH-induced transcriptional repression and highlight DaKr-h1 as a potential target for metamorphosis suppression in D. armandi.},
	keywords = {RNA Interference; 20-HYDROXYECDYSONE; Juvenile hormone; Broad-Complex; Kruppel homolog 1; Dendroctonus armandi},
	year = {2022},
	eissn = {1664-042X}
}

@article{MTMT:30902363,
	title = {Impairment of pupation by RNA interference-aided knockdown of Broad-Complex gene in Leptinotarsa decemlineata (Say)},
	url = {https://m2.mtmt.hu/api/publication/30902363},
	author = {Xu, Q-Y and Meng, Q-W and Deng, P. and Fu, K-Y and Guo, W-C and Li, G-Q},
	doi = {10.1017/S0007485318001050},
	journal-iso = {B ENTOMOL RES},
	journal = {BULLETIN OF ENTOMOLOGICAL RESEARCH},
	volume = {109},
	unique-id = {30902363},
	issn = {0007-4853},
	abstract = {Dietary delivery of bacterially expressed double-stranded RNA (dsRNA) has a great potential for management of Leptinotarsa decemlineata. An important first step is to discover possible RNA-interference (RNAi)-target genes effective against larvae, especially the old larvae. In the present paper, five putative Broad-Complex (BrC) cDNAs (Z1-Z4, and Z6) were identified in L. decemlineata. The expression of the five LdBrC isoforms was suppressed by juvenile hormone signaling, whereas the transcription was upregulated by 20-hydroxyecdysone signaling at the fourth (final) instar larval stage. Feeding of bacterially expressed dsBrC (derived from a common fragment of the five LdBrC variants) in the third- and fourth-instar larvae successfully knocked down the target mRNAs. For the fourth-instar LdBrC RNAi hypomorphs, they had a higher larval mortality compared with the controls. Moreover, most dsBrC-fed beetles did not pupate normally. After removal of the apolysed larval cuticle, a miniature adult was found. The adult head, compound eyes, prothorax, mesothorax, metathorax were found on the dorsal view. Distinct adult cuticle pigmentation was seen on the prothorax. The mouthparts, forelegs, midlegs, and hindlegs could be observed on the ventral view of the miniature adults. For the third-instar LdBrC RNAi specimens, around 20% moribund beetles remained as prepupae and finally died. Therefore, LdBrC is among the most attractive candidate genes for RNAi to control the fourth-instar larvae in L. decemlineata.},
	keywords = {RNA Interference; metamorphosis; Leptinotarsa decemlineata; Broad Complex; pupation},
	year = {2019},
	eissn = {1475-2670},
	pages = {659-668}
}

@article{MTMT:30902364,
	title = {Isoform specific roles of Broad-Complex in larval development in Leptinotarsa decemlineata},
	url = {https://m2.mtmt.hu/api/publication/30902364},
	author = {Xu, Q. -Y. and Meng, Q. -W. and Deng, P. and Fu, K. -Y. and Guo, W. -C. and Li, G. -Q.},
	doi = {10.1111/imb.12563},
	journal-iso = {INSECT MOL BIOL},
	journal = {INSECT MOLECULAR BIOLOGY},
	volume = {28},
	unique-id = {30902364},
	issn = {0962-1075},
	abstract = {Broad-Complex (BrC) is a downstream target of both 20-hydroxyecdysone and juvenile hormone signalling. BrC regulates morphogenetic changes between nymphal instars in hemimetabolans, whereas it controls pupal commitment, pupal morphogenesis and inhibits adult differentiation in holometabolans. Among five BrC cDNAs (Z1-Z4 and Z6) identified in the Colorado potato beetle, we found in this work that Z1, Z2 and Z6 were mainly expressed at the last (fourth) instar and prepupal stages, whereas the levels of Z3 and Z4 increased during the penultimate (third) instar stage, peaked at the last instar larval phase and gradually decreased at the prepupal and pupal periods. When knocking down all BrC isoforms by RNA interference (RNAi) at the penultimate instar stage, around 20% of the resultant larvae remained as moribund beetles. These moribund BrC RNAi larvae were completely or partially wrapped in old cuticle. Likewise, a portion of larvae treated for a single double-stranded RNA of Z3, Z4 or Z6 displayed a degree of similar aberrancies, increasing in the order of isoforms Z6 BrC isoforms at the last instar period, most of the RNAi larvae did not normally pupate or emerge as adults. Separately silencing each of the five zinc finger domains revealed that approximately 70% of the Z1 RNAi larvae remained as prepupae, around 60% of the Z6 RNAi specimens formed aberrant prepupae or pupae and about 60% of the Z2 RNAi beetles became deformed pupae. After removal of the old exuviae, these deformed larvae in which either Z1, Z2 or Z6 was depleted possessed adult prothorax and mesothorax, developing antenna, mouthparts and wing discs. Moreover, less than 50% of the resultant pupae finally emerged as adults when either of Z1, Z2 or Z6 was knocked down. Therefore, our findings reveal, for the first time, that the two roles of BrC in insect groups (ie directing morphogenetic changes during juvenile development and regulating larval-pupal-adult metamorphosis) are played by different BrC isoforms in Leptinotarsa decemlineata.},
	keywords = {metamorphosis; Leptinotarsa decemlineata; pupation; Broad-Complex},
	year = {2019},
	eissn = {1365-2583},
	pages = {420-430}
}

@article{MTMT:30465803,
	title = {Ecdysteroid and juvenile hormone biosynthesis, receptors and their signaling in the freshwater microcrustacean Daphnia},
	url = {https://m2.mtmt.hu/api/publication/30465803},
	author = {Miyakawa, Hitoshi and Sato, Tomomi and Song, You and Tollefsen, Knut Erik and Iguchi, Taisen},
	doi = {10.1016/j.jsbmb.2017.12.006},
	journal-iso = {J STEROID BIOCHEM MOL BIOL},
	journal = {JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY},
	volume = {184},
	unique-id = {30465803},
	issn = {0960-0760},
	abstract = {The two essential insect hormones, ecdysteroids and juvenile hormones, are possessed not only by insects, but also widely by arthropods, and regulate various developmental and physiological processes. In contrast to the abundant information about molecular endocrine mechanisms in insects, the knowledge of non-insect arthropod endocrinology is still limited. In this review, we summarize recent reports about the molecular basis of these to major insect hormones in the freshwater microcrustacean Daphnia, a keystone taxon in limnetic ecology and bioindicator in environmental studies. Comprehensive comparisons of endocrine signaling pathways between insects and daphnids may shed light on the regulatory mechanisms of various biological phenomena an, moreover, evolutionary processes of arthropod species.},
	keywords = {ecdysteroid; Daphnia magna; Juvenile hormone; Daphnia pulex; Hormonal crosstalk},
	year = {2018},
	eissn = {1879-1220},
	pages = {62-68}
}

@article{MTMT:26537160,
	title = {Molecular mechanism underlying juvenile hormone-mediated repression of precocious larval-adult metamorphosis},
	url = {https://m2.mtmt.hu/api/publication/26537160},
	author = {Kayukawa, Takumi and Jouraku, Akiya and Ito, Yuka and Shinoda, Tetsuro},
	doi = {10.1073/pnas.1615423114},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {114},
	unique-id = {26537160},
	issn = {0027-8424},
	year = {2017},
	eissn = {1091-6490},
	pages = {1057-1062}
}

@article{MTMT:26183633,
	title = {Kruppel Homolog 1 Inhibits Insect Metamorphosis via Direct Transcriptional Repression of Broad-Complex, a Pupal Specifier Gene},
	url = {https://m2.mtmt.hu/api/publication/26183633},
	author = {Kayukawa, Takumi and Nagamine, Keisuke and Ito, Yuka and Nishita, Yoshinori and Ishikawa, Yukio and Shinoda, Tetsuro},
	doi = {10.1074/jbc.M115.686121},
	journal-iso = {J BIOL CHEM},
	journal = {JOURNAL OF BIOLOGICAL CHEMISTRY},
	volume = {291},
	unique-id = {26183633},
	issn = {0021-9258},
	year = {2016},
	eissn = {1083-351X},
	pages = {1751-1762}
}

@article{MTMT:26183632,
	title = {Differential Juvenile Hormone Variations in Scale Insect Extreme Sexual Dimorphism},
	url = {https://m2.mtmt.hu/api/publication/26183632},
	author = {Vea, Isabelle Mifom and Tanaka, Sayumi and Shiotsuki, Takahiro and Jouraku, Akiya and Tanaka, Toshiharu and Minakuchi, Chieka},
	doi = {10.1371/journal.pone.0149459},
	journal-iso = {PLOS ONE},
	journal = {PLOS ONE},
	volume = {11},
	unique-id = {26183632},
	issn = {1932-6203},
	year = {2016},
	eissn = {1932-6203}
}

@article{MTMT:26183634,
	title = {Molecular cloning, characterization, and expression analysis of a Broad-Complex homolog during development in the oriental river prawn Macrobrachium nipponense},
	url = {https://m2.mtmt.hu/api/publication/26183634},
	author = {Jiang, S F and Zhang, Y P and Sun, S M and Gong, Y S and Xiong, Y W and Qiao, H and Zhang, W Y and Jin, S B and Fu, H T},
	doi = {10.4238/2015.May.18.4},
	journal-iso = {GENET MOL RES},
	journal = {GENETICS AND MOLECULAR RESEARCH},
	volume = {14},
	unique-id = {26183634},
	issn = {1676-5680},
	year = {2015},
	pages = {5141-5152}
}

@article{MTMT:24722126,
	title = {The COP9 Signalosome Converts Temporal Hormone Signaling to Spatial Restriction on Neural Competence},
	url = {https://m2.mtmt.hu/api/publication/24722126},
	author = {Huang, YC and Lu, YN and Wu, JT and Chien, CT and Pi, HW},
	doi = {10.1371/journal.pgen.1004760},
	journal-iso = {PLOS GENET},
	journal = {PLOS GENETICS},
	volume = {10},
	unique-id = {24722126},
	issn = {1553-7390},
	year = {2014},
	eissn = {1553-7404}
}

@article{MTMT:24090913,
	title = {3D-QSAR studies on the biological activity of juvenile hormone mimetic compounds for Culex pipiens Larvae},
	url = {https://m2.mtmt.hu/api/publication/24090913},
	author = {Latha, RS and Vijayaraj, R and Padmanabhan, J and Singam, ERA and Chitra, K and Subramanian, V},
	doi = {10.1007/s00044-013-0585-5},
	journal-iso = {MED CHEM RES},
	journal = {MEDICINAL CHEMISTRY RESEARCH},
	volume = {22},
	unique-id = {24090913},
	issn = {1054-2523},
	year = {2013},
	eissn = {1554-8120},
	pages = {5948-5960}
}

@article{MTMT:24090912,
	title = {The ecdysone receptor (ScEcR-A) binds DNA puffs at the start of DNA amplification in Sciara coprophila},
	url = {https://m2.mtmt.hu/api/publication/24090912},
	author = {Liew, GM and Foulk, MS and Gerbi, SA},
	doi = {10.1007/s10577-013-9360-1},
	journal-iso = {CHROMOSOME RES},
	journal = {CHROMOSOME RESEARCH},
	volume = {21},
	unique-id = {24090912},
	issn = {0967-3849},
	year = {2013},
	eissn = {1573-6849},
	pages = {345-360}
}

@article{MTMT:22104027,
	title = {Drosophila Met and Gce are partially redundant in transducing juvenile hormone action},
	url = {https://m2.mtmt.hu/api/publication/22104027},
	author = {Abdou, MA and He, QY and Wen, D and Zyaan, O and Wang, J and Xu, JJ and Baumann, AA and Joseph, J and Wilson, TG and Li, S and Wang, J},
	doi = {10.1016/j.ibmb.2011.09.003},
	journal-iso = {INSECT BIOCHEM MOLEC},
	journal = {INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY},
	volume = {41},
	unique-id = {22104027},
	issn = {0965-1748},
	year = {2011},
	eissn = {1879-0240},
	pages = {938-945}
}

@article{MTMT:21983909,
	title = {Developmental profile and hormonal regulation of the transcription factors broad and Kruppel homolog 1 in hemimetabolous thrips.},
	url = {https://m2.mtmt.hu/api/publication/21983909},
	author = {Minakuchi, C and Tanaka, M and Miura, K and Tanaka, T},
	doi = {10.1016/j.ibmb.2010.11.004},
	journal-iso = {INSECT BIOCHEM MOLEC},
	journal = {INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY},
	volume = {41},
	unique-id = {21983909},
	issn = {0965-1748},
	year = {2011},
	eissn = {1879-0240},
	pages = {125-134}
}

@article{MTMT:21983458,
	title = {Temporal patterns of broad isoform expression during the development of neuronal lineages in Drosophila},
	url = {https://m2.mtmt.hu/api/publication/21983458},
	author = {Zhou, B H and Williams, D W and Altman, J and Riddiford, L M and Truman, J W},
	doi = {10.1186/1749-8104-4-39},
	journal-iso = {NEURAL DEV},
	journal = {NEURAL DEVELOPMENT},
	volume = {4},
	unique-id = {21983458},
	issn = {1749-8104},
	year = {2009},
	eissn = {1749-8104}
}

@article{MTMT:22104041,
	title = {Kruppel homolog 1 (Kr-h1) mediates juvenile hormone action during metamorphosis of Drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/22104041},
	author = {Minakuchi, C and Zhou, X and Riddiford, LM},
	doi = {10.1016/j.mod.2007.10.002},
	journal-iso = {MECH DEVELOP},
	journal = {MECHANISMS OF DEVELOPMENT},
	volume = {125},
	unique-id = {22104041},
	issn = {0925-4773},
	year = {2008},
	eissn = {1872-6356},
	pages = {91-105}
}

@article{MTMT:22104040,
	title = {The role of 20-hydroxyecdysone and juvenile hormone in pupal commitment of the epidermis of the silkworm, Bombyx mori},
	url = {https://m2.mtmt.hu/api/publication/22104040},
	author = {Muramatsu, D and Kinjoh, T and Shinoda, T and Hiruma, K},
	doi = {10.1016/j.mod.2008.02.001},
	journal-iso = {MECH DEVELOP},
	journal = {MECHANISMS OF DEVELOPMENT},
	volume = {125},
	unique-id = {22104040},
	issn = {0925-4773},
	year = {2008},
	eissn = {1872-6356},
	pages = {411-420}
}

@article{MTMT:24519438,
	title = {Transcription factor broad suppresses precocious development of adult structures during larval-pupal metamorphosis in the red flour beetle, Tribolium castaneum},
	url = {https://m2.mtmt.hu/api/publication/24519438},
	author = {Parthasarathy, R and Tan, A and Bai, H and Palli, SR},
	doi = {10.1016/j.mod.2007.11.001},
	journal-iso = {MECH DEVELOP},
	journal = {MECHANISMS OF DEVELOPMENT},
	volume = {125},
	unique-id = {24519438},
	issn = {0925-4773},
	year = {2008},
	eissn = {1872-6356},
	pages = {299-313}
}

@article{MTMT:23389046,
	title = {Broad-Complex, E74, and E75 early genes control DNA puff BhC4-1 expression in prepupal salivary glands},
	url = {https://m2.mtmt.hu/api/publication/23389046},
	author = {Basso, LR and Neves, MD and Monesi, N and Paco-Larson, ML},
	doi = {10.1002/dvg.20239},
	journal-iso = {GENESIS},
	journal = {GENESIS: THE JOURNAL OF GENETICS AND DEVELOPMENT},
	volume = {44},
	unique-id = {23389046},
	issn = {1526-954X},
	year = {2006},
	eissn = {1526-968X},
	pages = {505-514}
}

@article{MTMT:22068802,
	title = {Imperfect eggs and oviform nymphs: a history of ideas about the origins of insect metamorphosis},
	url = {https://m2.mtmt.hu/api/publication/22068802},
	author = {Erezyilmaz, D F},
	doi = {10.1093/icb/icl033},
	journal-iso = {INTEGR COMP BIOL},
	journal = {INTEGRATIVE AND COMPARATIVE BIOLOGY},
	volume = {46},
	unique-id = {22068802},
	issn = {1540-7063},
	year = {2006},
	eissn = {1557-7023},
	pages = {795-807}
}

@article{MTMT:21979292,
	title = {The pupal specifier broad directs progressive morphogenesis in a direct-developing insect},
	url = {https://m2.mtmt.hu/api/publication/21979292},
	author = {Erezyilmaz, D F and Riddiford, L M and Truman, J W},
	doi = {10.1073/pnas.0509983103},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {103},
	unique-id = {21979292},
	issn = {0027-8424},
	year = {2006},
	eissn = {1091-6490},
	pages = {6925-6930}
}

@article{MTMT:21982686,
	title = {Differential usage of two promoters of the Broad-Complex gene in the silkworm, Bombyx mori},
	url = {https://m2.mtmt.hu/api/publication/21982686},
	author = {Nishita, Y and Takiya, S},
	doi = {10.1016/j.ibmb.2006.07.005},
	journal-iso = {INSECT BIOCHEM MOLEC},
	journal = {INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY},
	volume = {36},
	unique-id = {21982686},
	issn = {0965-1748},
	year = {2006},
	eissn = {1879-0240},
	pages = {779-788}
}

@article{MTMT:22225497,
	title = {Border of Notch activity establishes a boundary between the two dorsal appendage tube cell types},
	url = {https://m2.mtmt.hu/api/publication/22225497},
	author = {Ward, EJ and Zhou, XF and Riddiford, LM and Berg, CA and Ruohola-Baker, H},
	doi = {10.1016/j.ydbio.2006.05.021},
	journal-iso = {DEV BIOL},
	journal = {DEVELOPMENTAL BIOLOGY},
	volume = {297},
	unique-id = {22225497},
	issn = {0012-1606},
	year = {2006},
	eissn = {1095-564X},
	pages = {461-470}
}

@article{MTMT:22104063,
	title = {Hormonal control of a metamorphosis-specific transcriptional factor Broad-Complex in silkworm},
	url = {https://m2.mtmt.hu/api/publication/22104063},
	author = {Reza, Ams and Kanamori, Y and Shinoda, T and Shimura, S and Mita, K and Nakahara, Y and Kiuchi, M and Kamimura, M},
	doi = {10.1016/j.cbpc.2004.09.009},
	journal-iso = {COMP BIOCHEM PHYS B},
	journal = {COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY},
	volume = {139},
	unique-id = {22104063},
	issn = {1096-4959},
	year = {2004},
	eissn = {1879-1107},
	pages = {753-761}
}

@article{MTMT:22104061,
	title = {Overexpression of broad: a new insight into its role in the Drosophila prothoracic gland cells},
	url = {https://m2.mtmt.hu/api/publication/22104061},
	author = {Zhou, XF and Zhou, BH and Truman, JW and Riddiford, LM},
	doi = {10.1242/jeb.00855},
	journal-iso = {J EXP BIOL},
	journal = {JOURNAL OF EXPERIMENTAL BIOLOGY},
	volume = {207},
	unique-id = {22104061},
	issn = {0022-0949},
	year = {2004},
	eissn = {1477-9145},
	pages = {1151-1161}
}

@article{MTMT:22104070,
	title = {Evolution of the Drosophila broad locus: the Manduca sexta broad Z4 isoform has biological activity in Drosophila},
	url = {https://m2.mtmt.hu/api/publication/22104070},
	author = {Bayer, C and Zhou, XF and Zhou, BH and Riddiford, LM and von Kalm, L},
	doi = {10.1007/s00427-003-0354-4},
	journal-iso = {DEV GENES EVOL},
	journal = {DEVELOPMENT GENES AND EVOLUTION},
	volume = {213},
	unique-id = {22104070},
	issn = {0949-944X},
	year = {2003},
	eissn = {1432-041X},
	pages = {471-476}
}

@article{MTMT:22104080,
	title = {Broad specifies pupal development and mediates the 'status quo' action of juvenile hormone on the pupal-adult transformation in Drosophila and Manduca},
	url = {https://m2.mtmt.hu/api/publication/22104080},
	author = {Zhou, XF and Riddiford, LM},
	journal-iso = {DEVELOPMENT},
	journal = {DEVELOPMENT},
	volume = {129},
	unique-id = {22104080},
	issn = {0950-1991},
	year = {2002},
	eissn = {1477-9129},
	pages = {2259-2269}
}

@article{MTMT:21979230,
	title = {Selective binding of Drosophila BR-C isoforms to a distal regulatory element in the hsp23 promoter},
	url = {https://m2.mtmt.hu/api/publication/21979230},
	author = {Dubrovsky, E B and Dubrovskaya, V A and Berger, E M},
	doi = {10.1016/S0965-1748(01)00071-6},
	journal-iso = {INSECT BIOCHEM MOLEC},
	journal = {INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY},
	volume = {31},
	unique-id = {21979230},
	issn = {0965-1748},
	year = {2001},
	eissn = {1879-0240},
	pages = {1231-1239}
}

@article{MTMT:22104094,
	title = {Dynamic Expression of Broad-Complex Isoforms Mediates Temporal Control of an Ecdysteroid Target Gene at the Onset of Drosophila Metamorphosis.},
	url = {https://m2.mtmt.hu/api/publication/22104094},
	author = {Mugat, B and Brodu, V and Kejzlarovalepes and Antoniewski, C and Bayer, CA and Fristrom, JW and Lepesant, JA},
	doi = {10.1006/dbio.2000.9879},
	journal-iso = {DEV BIOL},
	journal = {DEVELOPMENTAL BIOLOGY},
	volume = {227},
	unique-id = {22104094},
	issn = {0012-1606},
	year = {2000},
	eissn = {1095-564X},
	pages = {104-117}
}

@article{MTMT:22554941,
	title = {Genetic Organization of Polytene Chromosomes.},
	url = {https://m2.mtmt.hu/api/publication/22554941},
	author = {Zhimulev, IF},
	doi = {10.1016/S0065-2660(08)60476-9},
	journal-iso = {ADV GENET},
	journal = {ADVANCES IN GENETICS},
	volume = {39},
	unique-id = {22554941},
	issn = {0065-2660},
	year = {1999},
	pages = {1-589}
}

@article{MTMT:22063728,
	title = {The Broad-Complex Gene Is a Tissue-Specific Modulator of the Ecdysone Response of the Drosophila Hsp23 Gene.},
	url = {https://m2.mtmt.hu/api/publication/22063728},
	author = {Dubrovsky, EB and Dretzen, G and Berger, EM},
	journal-iso = {MOL CELL BIOL},
	journal = {MOLECULAR AND CELLULAR BIOLOGY},
	volume = {16},
	unique-id = {22063728},
	issn = {0270-7306},
	year = {1996},
	eissn = {1098-5549},
	pages = {6542-6552}
}

@article{MTMT:22104130,
	title = {The Ecdysone-Inducible Broad-Complex and E74 Early Genes Interact to Regulate Target Gene-Transcription and Drosophila Metamorphosis.},
	url = {https://m2.mtmt.hu/api/publication/22104130},
	author = {Fletcher, JC and Thummel, CS},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {141},
	unique-id = {22104130},
	issn = {0016-6731},
	year = {1995},
	eissn = {1943-2631},
	pages = {1025-1035}
}

@article{MTMT:22104129,
	title = {The Making of a Fly Leg - A Model for Epithelial Morphogenesis.},
	url = {https://m2.mtmt.hu/api/publication/22104129},
	author = {Vonkalm, L and Fristrom, D and Fristrom, J},
	doi = {10.1002/bies.950170806},
	journal-iso = {BIOESSAYS},
	journal = {BIOESSAYS},
	volume = {17},
	unique-id = {22104129},
	issn = {0265-9247},
	year = {1995},
	eissn = {1521-1878},
	pages = {693-702}
}

@article{MTMT:22064663,
	title = {Molecular Cytogenetic Organization of Polytene Chromosomes.},
	url = {https://m2.mtmt.hu/api/publication/22064663},
	author = {Zhimulev, IF and Belyaeva, ES and Semeshin, VF and Pokholkova, GV and Kokoza, EB and Kozlova, TY and Demakov, SA and Malceva, NI and Demakova, OV and Balasov, ML and Koryakov, DE and Makunin, IV and Belousova, NV},
	doi = {10.1007/BF01151271},
	journal-iso = {RUSS CHEM B+},
	journal = {RUSSIAN CHEMICAL BULLETIN},
	volume = {44},
	unique-id = {22064663},
	issn = {1066-5285},
	year = {1995},
	eissn = {1573-9171},
	pages = {1553-1570}
}

@article{MTMT:22137407,
	title = {Steroid-Receptors and Other Transcription Factors in Ecdysone Response.},
	url = {https://m2.mtmt.hu/api/publication/22137407},
	author = {Segraves, WA},
	journal-iso = {RECENT PROG HORM RES},
	journal = {RECENT PROGRESS IN HORMONE RESEARCH},
	volume = {49},
	unique-id = {22137407},
	issn = {0079-9963},
	year = {1994},
	pages = {167-195}
}

@article{MTMT:22104145,
	title = {The Drosophila Broad-Complex Plays a Key Role in Controlling Ecdysone-Regulated Gene-Expression at the Onset of Metamorphosis.},
	url = {https://m2.mtmt.hu/api/publication/22104145},
	author = {Karim, FD and Guild, GM and Thummel, CS},
	journal-iso = {DEVELOPMENT},
	journal = {DEVELOPMENT},
	volume = {118},
	unique-id = {22104145},
	issn = {0950-1991},
	year = {1993},
	eissn = {1477-9129},
	pages = {977-988}
}

@article{MTMT:21983037,
	title = {PROSPECTS OF USING DROSOPHILA FOR INSECT NEUROENDOCRINE RESEARCH},
	url = {https://m2.mtmt.hu/api/publication/21983037},
	author = {Segal, D},
	doi = {10.1002/arch.940220116},
	journal-iso = {ARCH INSECT BIOCHEM},
	journal = {ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY},
	volume = {22},
	unique-id = {21983037},
	issn = {0739-4462},
	year = {1993},
	eissn = {1520-6327},
	pages = {199-231}
}

@article{MTMT:22656669,
	title = {Mutations in a Steroid Hormone-Regulated Gene Disrupt the Metamorphosis of Internal Tissues in Drosophila - Salivary- Glands, Muscle, and Gut.},
	url = {https://m2.mtmt.hu/api/publication/22656669},
	author = {Restifo, LL and White, K},
	journal-iso = {ROUX ARCH DEV BIOL},
	journal = {ROUXS ARCHIVES OF DEVELOPMENTAL BIOLOGY},
	volume = {201},
	unique-id = {22656669},
	issn = {0930-035X},
	year = {1992},
	pages = {221-234}
}

@article{MTMT:25752344,
	title = {MUTATIONS IN A STEROID HORMONE-REGULATED GENE DISRUPT THE METAMORPHOSIS OF INTERNAL TISSUES IN DROSOPHILA - SALIVARY-GLANDS, MUSCLE, AND GUT},
	url = {https://m2.mtmt.hu/api/publication/25752344},
	author = {RESTIFO, LL and WHITE, K},
	doi = {10.1007/BF00188753},
	journal-iso = {ROUX ARCH DEV BIOL},
	journal = {ROUXS ARCHIVES OF DEVELOPMENTAL BIOLOGY},
	volume = {201},
	unique-id = {25752344},
	issn = {0930-035X},
	year = {1992},
	pages = {221-234}
}

@article{MTMT:22104159,
	title = {The Drosophila Broad-Complex Encodes a Family of Related Proteins Containing Zinc Fingers.},
	url = {https://m2.mtmt.hu/api/publication/22104159},
	author = {Dibello, PR and Withers, DA and Bayer, CA and Fristrom, JW and Guild, GM},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {129},
	unique-id = {22104159},
	issn = {0016-6731},
	year = {1991},
	eissn = {1943-2631},
	pages = {385-397}
}

@article{MTMT:22064730,
	title = {CYTOGENETICAL ANALYSIS OF THE 2B3-4-2B11 REGION OF THE X-CHROMOSOME OF DROSOPHILA-MELANOGASTER .7. INFLUENCE OF THE ECS LOCUS ON FEMALE FERTILITY},
	url = {https://m2.mtmt.hu/api/publication/22064730},
	author = {Mazina, OM and Belyaeva, ES and Zhimulev, IF},
	journal-iso = {MOL GEN GENET},
	journal = {MOLECULAR & GENERAL GENETICS},
	volume = {225},
	unique-id = {22064730},
	issn = {0026-8925},
	year = {1991},
	eissn = {1432-1874},
	pages = {99-105}
}

@article{MTMT:22687171,
	title = {Studies on the Nature of Female-Sterile Mutations at the Ecs Locus Responsible for Sensitivity to Ecdysterone in Drosophila-Melanogaster.},
	url = {https://m2.mtmt.hu/api/publication/22687171},
	author = {Mazina, OM and Korochkina, SE},
	volume = {27},
	unique-id = {22687171},
	year = {1991},
	pages = {1920-1927}
}

@article{MTMT:23406505,
	title = {STUDIES ON THE NATURE OF FEMALE-STERILE MUTATIONS AT THE ECS LOCUS RESPONSIBLE FOR SENSITIVITY TO ECDYSTERONE IN DROSOPHILA-MELANOGASTER},
	url = {https://m2.mtmt.hu/api/publication/23406505},
	author = {MAZINA, OM and KOROCHKINA, SE},
	journal-iso = {GENETIKA},
	journal = {GENETIKA},
	volume = {27},
	unique-id = {23406505},
	issn = {0016-6758},
	year = {1991},
	pages = {1920-1927}
}

@article{MTMT:22104161,
	title = {Mutations in a Steroid Hormone-Regulated Gene Disrupt the Metamorphosis of the Central-Nervous-System in Drosophila.},
	url = {https://m2.mtmt.hu/api/publication/22104161},
	author = {Restifo, LL and White, K},
	doi = {10.1016/0012-1606(91)90328-Z},
	journal-iso = {DEV BIOL},
	journal = {DEVELOPMENTAL BIOLOGY},
	volume = {148},
	unique-id = {22104161},
	issn = {0012-1606},
	year = {1991},
	eissn = {1095-564X},
	pages = {174-194}
}

@article{MTMT:21979617,
	title = {TRANSCRIPTION AT THE ECDYSONE-INDUCIBLE LOCUS-2B5 IN DROSOPHILA},
	url = {https://m2.mtmt.hu/api/publication/21979617},
	author = {Galceran, J and Llanos, J and Sampedro, J and Pongs, O and Izquierdo, M},
	doi = {10.1093/nar/18.3.539},
	journal-iso = {NUCLEIC ACIDS RES},
	journal = {NUCLEIC ACIDS RESEARCH},
	volume = {18},
	unique-id = {21979617},
	issn = {0305-1048},
	year = {1990},
	eissn = {1362-4962},
	pages = {539-545}
}

@article{MTMT:22064731,
	title = {INFLUENCE OF THE DROSOPHILA-MELANOGASTER ECS LOCUS ON FEMALE FERTILITY},
	url = {https://m2.mtmt.hu/api/publication/22064731},
	author = {Mazina, OM and Belyaeva, ES and Graphodatskaya, VE and Zhimulev, IF},
	journal-iso = {GENETIKA},
	journal = {GENETIKA},
	volume = {26},
	unique-id = {22064731},
	issn = {0016-6758},
	year = {1990},
	pages = {1038-1045}
}

@article{MTMT:22104166,
	title = {Mutation Mapping of the 2B5 Ecdysone Locus in Drosophila-Melanogaster Reveals a Long-Distance Controlling Element.},
	url = {https://m2.mtmt.hu/api/publication/22104166},
	author = {Sampedro, J and Izquierdo, M and Galceran, J},
	journal-iso = {MOL CELL BIOL},
	journal = {MOLECULAR AND CELLULAR BIOLOGY},
	volume = {9},
	unique-id = {22104166},
	issn = {0270-7306},
	year = {1989},
	eissn = {1098-5549},
	pages = {3588-3591}
}

@article{MTMT:1904570,
	title = {Interactions and developmental effects of mutations at the 2B5 locus of Drosophila melanogaster.},
	url = {https://m2.mtmt.hu/api/publication/1904570},
	author = {Kiss, István and BEATON, AH and TARDIFF, J and FRISTROM, D and FRISTROM, JW},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {118},
	unique-id = {1904570},
	issn = {0016-6731},
	year = {1988},
	eissn = {1943-2631},
	pages = {247-259}
}

@article{MTMT:22064734,
	title = {CYTOGENETIC ANALYSIS OF 2B1-2-2B9-10 OF THE X-CHROMOSOME OF DROSOPHILA MELANOGASTER .7. CLONING OF THE ECS, DOR AND SWI LOCI},
	url = {https://m2.mtmt.hu/api/publication/22064734},
	author = {Protopopov, MO and Belyaeva, ES and Kokoza, EB and Sharapova, EM and Baricheva, EM and Demakova, OV and Grafodatskaya, VE and Zhimulev, IF},
	journal-iso = {GENETIKA},
	journal = {GENETIKA},
	volume = {24},
	unique-id = {22064734},
	issn = {0016-6758},
	year = {1988},
	pages = {1614-1623}
}

@article{MTMT:22068835,
	title = {The Action of the L(1)NPR-1+ Locus on the Drosophila Glue Gene Sgs-3 Is Cell-Autonomous.},
	url = {https://m2.mtmt.hu/api/publication/22068835},
	author = {Raghavan, KV and Meyerowitz, EM and Mayeda, C},
	doi = {10.1007/BF02927825},
	journal-iso = {J GENET},
	journal = {JOURNAL OF GENETICS},
	volume = {67},
	unique-id = {22068835},
	issn = {0022-1333},
	year = {1988},
	eissn = {0973-7731},
	pages = {141-150}
}

@article{MTMT:22137721,
	title = {CYTOGENETIC ANALYSIS OF REGION 2B3-4-2B11 OF THE X-CHROMOSOME OF DROSOPHILA-MELANOGASTER .6. MOLECULAR AND CYTOLOGICAL MAPPING OF THE ECS LOCUS AND THE 2B PUFF},
	url = {https://m2.mtmt.hu/api/publication/22137721},
	author = {Belyaeva, ES and Protopopov, MO and Baricheva, EM and Semeshin, VF and Izquierdo, ML and Zhimulev, IF},
	doi = {10.1007/BF00294787},
	journal-iso = {CHROMOSOMA},
	journal = {CHROMOSOMA},
	volume = {95},
	unique-id = {22137721},
	issn = {0009-5915},
	year = {1987},
	eissn = {1432-0886},
	pages = {295-310}
}

@article{MTMT:1899417,
	title = {The mode of action of "discless" mutations in Drosophila melanogaster.},
	url = {https://m2.mtmt.hu/api/publication/1899417},
	author = {Szabad, János and BRYANT, PJ},
	doi = {10.1016/0012-1606(82)90256-1},
	journal-iso = {DEV BIOL},
	journal = {DEVELOPMENTAL BIOLOGY},
	volume = {93},
	unique-id = {1899417},
	issn = {0012-1606},
	year = {1982},
	eissn = {1095-564X},
	pages = {240-256}
}

@article{MTMT:21983434,
	title = {CYTOGENETIC ANALYSIS OF THE 2B3-4-2B11 REGION OF THE X-CHROMOSOME OF DROSOPHILA-MELANOGASTER .3. PUFFING DISTURBANCE IN SALIVARY-GLAND CHROMOSOMES OF HOMOZYGOTES FOR MUTATION L(1)PPLT10},
	url = {https://m2.mtmt.hu/api/publication/21983434},
	author = {Zhimulev, I F and Vlassova, I E and Belyaeva, E S},
	doi = {10.1007/BF00330779},
	journal-iso = {CHROMOSOMA},
	journal = {CHROMOSOMA},
	volume = {85},
	unique-id = {21983434},
	issn = {0009-5915},
	year = {1982},
	eissn = {1432-0886},
	pages = {569-672}
}

@article{MTMT:22137724,
	title = {CYTOGENETIC ANALYSIS OF THE 2B3-4-2B11 REGION OF THE X- CHROMOSOME OF DROSOPHILA-MELANOGASTER .2. CHANGES IN 20-OH ECDYSONE PUFFING CAUSED BY GENETIC-DEFECTS OF PUFF-2B5},
	url = {https://m2.mtmt.hu/api/publication/22137724},
	author = {Belyaeva, ES and Vlassova, IE and Biyasheva, ZM and Kakpakov, VT and Richards, G and Zhimulev, IF},
	doi = {10.1007/BF00399132},
	journal-iso = {CHROMOSOMA},
	journal = {CHROMOSOMA},
	volume = {84},
	unique-id = {22137724},
	issn = {0009-5915},
	year = {1981},
	eissn = {1432-0886},
	pages = {207-219}
}

@article{MTMT:22064737,
	title = {2 CLOSELY LINKED LOCI CONTROLLING ECDYSONE-DEPENDENT PUFFING IN DROSOPHILA-MELANOGASTER},
	url = {https://m2.mtmt.hu/api/publication/22064737},
	author = {Biiasheva, ZM and Zhimulev, IF and Kakpakov, VT and Richards, G and Aizenzon, MG and Beliaeva, ES},
	journal-iso = {DOKL AKAD NAUK SSSR},
	journal = {DOKLADY AKADEMII NAUK SSSR},
	volume = {256},
	unique-id = {22064737},
	issn = {0002-3264},
	year = {1981},
	eissn = {0012-4982},
	pages = {983}
}

@article{MTMT:2840272,
	title = {Imaginal disc development in a non-pupariating lethal mutant in Drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/2840272},
	author = {Fristrom, DK and Fekete, Éva and Fristrom, JW},
	journal-iso = {WILH ROUX S ARC DEV BIOL},
	journal = {WILHELM ROUX S ARCHIVES OF DEVELOPMENTAL BIOLOGY},
	volume = {190},
	unique-id = {2840272},
	issn = {0340-0794},
	year = {1981},
	pages = {11-21}
}

@article{MTMT:22137502,
	title = {CHROMOSOMAL ACTION OF ECDYSONE},
	url = {https://m2.mtmt.hu/api/publication/22137502},
	author = {Ashburner, M},
	doi = {10.1038/285435a0},
	journal-iso = {NATURE},
	journal = {NATURE},
	volume = {285},
	unique-id = {22137502},
	issn = {0028-0836},
	year = {1980},
	eissn = {1476-4687},
	pages = {435-436}
}

@article{MTMT:1899746,
	title = {Cytogenetic analysis of the 2B3-4-2B11 region of the X chromosome of Drosophila melanogaster. I. Cytology of the region and mutant complementation groups.},
	url = {https://m2.mtmt.hu/api/publication/1899746},
	author = {BELYAEVA, ES and AIZENZON, MG and SEMESHIN, VF and Kiss, István and Koczka, Katalin and BARITCHEVA, EM and GOREM, D and ZHIMULEV, IF},
	doi = {10.1007/BF00285954},
	journal-iso = {CHROMOSOMA},
	journal = {CHROMOSOMA},
	volume = {81},
	unique-id = {1899746},
	issn = {0009-5915},
	year = {1980},
	eissn = {1432-0886},
	pages = {281-306}
}

@article{MTMT:22064739,
	title = {CYTOGENETIC ANALYSIS OF THE DROSOPHILA-MELANOGASTER X-CHROMOSOME REGION 2B1-2-2B9-10 .3. CHANGES OF PUFFING PATTERNS IN SALIVARY-GLAND CHROMOSOMES OF LARVAE HOMOZYGOUS FOR MUTATION 1(1)PP-T10},
	url = {https://m2.mtmt.hu/api/publication/22064739},
	author = {Zhimulev, IF and Belyaeva, ES and Aizenzon, MG},
	journal-iso = {GENETIKA},
	journal = {GENETIKA},
	volume = {16},
	unique-id = {22064739},
	issn = {0016-6758},
	year = {1980},
	pages = {1613-1631}
}

@article{MTMT:1900772,
	title = {Genetic and developmental analysis of puparium formation in Drosophila.},
	url = {https://m2.mtmt.hu/api/publication/1900772},
	author = {Kiss, István and Szabad, János and Major, J.},
	doi = {10.1007/BF00267601},
	journal-iso = {MOL GEN GENET},
	journal = {MOLECULAR & GENERAL GENETICS},
	volume = {164},
	unique-id = {1900772},
	issn = {0026-8925},
	year = {1978},
	eissn = {1432-1874},
	pages = {77-83}
}

@article{MTMT:21982681,
	title = {ASPECTS OF DEVELOPMENT OF IMAGINAL DISKS IN A NON-PUPARIATING LETHAL MUTANT IN DROSOPHILA-MELANOGASTER},
	url = {https://m2.mtmt.hu/api/publication/21982681},
	author = {Murphy, C and Fristrom, J W and Shearn, A},
	doi = {10.1016/0045-6039(77)90007-0},
	journal-iso = {CELL DIFFER},
	journal = {CELL DIFFERENTIATION},
	volume = {6},
	unique-id = {21982681},
	issn = {0045-6039},
	year = {1977},
	pages = {319-330}
}