TY - JOUR AU - Dézsi, Anna AU - Erdei, Csilla AU - Demeter, Tamás AU - Kovács, Alexandra AU - Nagy, Gábor AU - Mensch, Károly AU - Németh, Orsolya AU - Hermann, Péter AU - Tóth, György AU - Füst, Ágnes AU - Kiss, Emese AU - Kőhidai, László AU - Zalatnai, Attila AU - Márton, Krisztina TI - Prevalence of Sjögren’s Syndrome in Patients with Dry Mouth in the Region of Central Hungary JF - ORAL DISEASES J2 - ORAL DIS VL - 29 PY - 2023 IS - 7 SP - 2756 EP - 2764 PG - 9 SN - 1354-523X DO - 10.1111/odi.14264 UR - https://m2.mtmt.hu/api/publication/32847862 ID - 32847862 AB - Abstract Objective One third of the Hungarian population suffers from xerostomia. Since there is no evidence on the actual prevalence of Sjögren?s syndrome (SS) in Hungary, this study aimed to evaluate the same. Materials and Methods Data were collected from the Faculty of Dentistry, Semmelweis University from 2008 to 2015. A diagnosis of SS was established based on the American College of Rheumatology and European League Against Rheumatism criteria. Results Of the 1,076 patients examined with sicca symptoms, 188 patients, had confirmed SS. Primary SS (pSS) was diagnosed in 135 patients, secondary SS (sSS) was confirmed in 53 patients. According to the available statistical records of the public health service of Hungary, there were an average of 16 (0.0014%, 5-26) newly diagnosed SS cases in the entire population and 141 SS patient-practitioner consultations (49-232) per 100,000 inhabitants in the country over the past 10?years (based on the past 10?years: 2011-2020). Conclusion Results revealed that approximately 1/5th?1/6th of patients with sicca symptoms have SS, among whom 72% and 285 have pSS and sSS, respectively. Global Hungarian records simultaneously revealed that the number of both new diagnoses and doctor-SS patient encounters has significantly decreased (by 50%) yearly over the last decade. LA - English DB - MTMT ER - TY - JOUR AU - Csurgay, Katalin AU - Zalatnai, Attila AU - Benczik, Márta AU - Csomó, Krisztián Benedek AU - Horváth, Ferenc AU - Lőrincz, Ádám AU - Komlós, György AU - Németh, Zsolt TI - A Study of Prognostic Factors in Young Patients With Non-HPV Oral Cancer in Central Europe JF - PATHOLOGY AND ONCOLOGY RESEARCH J2 - PATHOL ONCOL RES VL - 27 PY - 2021 PG - 11 SN - 1219-4956 DO - 10.3389/pore.2021.1609991 UR - https://m2.mtmt.hu/api/publication/32568337 ID - 32568337 N1 - Export Date: 19 March 2022 CODEN: POREF AB - The etiological factors of squamous cell carcinomas of the head and neck have been well known for a long time. It is also well known that the incidence of oral cancer diagnosed in younger patients is on the rise. Due to the young age of these patients, the increase in the number of these cases and the fact that many of them neither smoke nor drink alcohol it has been suggested that other factors might be at play in the carcinogenesis of oral cancer. Thus, along the classic etiological factors of smoking and alcohol abuse certain molecular marker anomalies and the human papilloma virus (HPV) have emerged as potential factors. The aim of the present study is to verify the potential prognostic factors and to map the differences in biomarker expression between the young and the old patient groups. In the present study the immunohistochemical profile of samples obtained from oral squamous cell carcinomas was studied and compared with various clinico-pathological parameters. In 88 samples the expressions of p16, p53, Ki67, EGFR were studied with a tissue microarray technique under standard reaction conditions as well as the detection and typing of HPV infection with the Full Spectrum HPV DNA method. The biomarker expression profile of young patients with oral squamous cell carcinoma was compared to that of older patients (above 50). A significant difference was found between the immunohistochemical profile of the young and old patient groups in p16, Ki67 expression. The overall survival and progression free survival were influenced by p16 expression in young age. LA - English DB - MTMT ER - TY - JOUR AU - Dézsi, Anna AU - Erdei, Csilla AU - Demeter, Tamás AU - Kovács, Alexandra AU - Márton, Krisztina TI - Histopathological Sample Preparation with Unique Biopsy Forceps in The Diagnosis of Sjögren’s Syndrome JF - JOURNAL OF DENTISTRY & ORAL HEALTH J2 - J DENT ORAL HEALTH VL - 8 PY - 2021 PG - 5 SN - 2332-4856 DO - 10.17303/jdoh.2021.8.103 UR - https://m2.mtmt.hu/api/publication/32007893 ID - 32007893 LA - English DB - MTMT ER - TY - JOUR AU - Mensch, Károly AU - Szarka, Krisztina Zsuzsanna AU - Mensch, H AU - Dobai, Adrienn AU - Magyar, Z AU - Pacurar, M AU - Vartolomei, AC AU - Manuc, D AU - Dobó-Nagy, Csaba TI - PCR Technique Assisting the Early Diagnosis of Human Papillomavirus. A retrospective clinical study TS - A retrospective clinical study JF - REVISTA DE CHIMIE J2 - REV CHIM-BUCHAREST VL - 69 PY - 2018 IS - 10 SP - 2781 EP - 2787 PG - 7 SN - 0034-7752 DO - 10.37358/rc.18.10.6624 UR - https://m2.mtmt.hu/api/publication/30337024 ID - 30337024 N1 - Department of Oral Diagnostics, Faculty of Dentistry, Semmelweis University, Budapest, Hungary University of Debrecen, Department of Medical Microbiology, Debrecen, Hungary Hospital and Casualty Centre, Sandor Peterfy Street, Budapest, Hungary Department of Oro-Maxillofacial Surgery and Stomatology, Semmelweis University, Budapest, Hungary University of Medicine and Pharmacy Targu Mures, Department of Orthodontics, 38 Gh. Marinescu Str., Targu Mures, 540139, Romania University of Medicine and Pharmacy Carol Davila Bucharest, Management and Public Health Department, 1-3 Dr.Leonte Anastasievici Str., Bucharest, 050463, Romania Cited By :3 Export Date: 28 January 2023 CODEN: RCBUA Correspondence Address: Manuc, D.; University of Medicine and Pharmacy Carol Davila Bucharest, 1-3 Dr.Leonte Anastasievici Str., Romania; email: d_manuc@yahoo.com LA - English DB - MTMT ER - TY - JOUR AU - Kis, Andrea AU - Fehér, Enikő AU - Gáll, Tamás AU - Tar, Ildikó AU - Boda, Róbert AU - D. Tóth, Etelka AU - Méhes, Gábor AU - Gergely, Lajos AU - Szarka, Krisztina Zsuzsanna TI - Epstein-Barr virus prevalence in oral squamous cell cancer and in potentially malignant oral disorders in an eastern Hungarian population JF - EUROPEAN JOURNAL OF ORAL SCIENCES J2 - EUR J ORAL SCI VL - 117 PY - 2009 IS - 5 SP - 536 EP - 540 PG - 5 SN - 0909-8836 DO - 10.1111/j.1600-0722.2009.00660.x UR - https://m2.mtmt.hu/api/publication/1342316 ID - 1342316 LA - English DB - MTMT ER -