@article{MTMT:32847862, title = {Prevalence of Sjögren’s Syndrome in Patients with Dry Mouth in the Region of Central Hungary}, url = {https://m2.mtmt.hu/api/publication/32847862}, author = {Dézsi, Anna and Erdei, Csilla and Demeter, Tamás and Kovács, Alexandra and Nagy, Gábor and Mensch, Károly and Németh, Orsolya and Hermann, Péter and Tóth, György and Füst, Ágnes and Kiss, Emese and Kőhidai, László and Zalatnai, Attila and Márton, Krisztina}, doi = {10.1111/odi.14264}, journal-iso = {ORAL DIS}, journal = {ORAL DISEASES}, volume = {29}, unique-id = {32847862}, issn = {1354-523X}, abstract = {Abstract Objective One third of the Hungarian population suffers from xerostomia. Since there is no evidence on the actual prevalence of Sjögren?s syndrome (SS) in Hungary, this study aimed to evaluate the same. Materials and Methods Data were collected from the Faculty of Dentistry, Semmelweis University from 2008 to 2015. A diagnosis of SS was established based on the American College of Rheumatology and European League Against Rheumatism criteria. Results Of the 1,076 patients examined with sicca symptoms, 188 patients, had confirmed SS. Primary SS (pSS) was diagnosed in 135 patients, secondary SS (sSS) was confirmed in 53 patients. According to the available statistical records of the public health service of Hungary, there were an average of 16 (0.0014%, 5-26) newly diagnosed SS cases in the entire population and 141 SS patient-practitioner consultations (49-232) per 100,000 inhabitants in the country over the past 10?years (based on the past 10?years: 2011-2020). Conclusion Results revealed that approximately 1/5th?1/6th of patients with sicca symptoms have SS, among whom 72% and 285 have pSS and sSS, respectively. Global Hungarian records simultaneously revealed that the number of both new diagnoses and doctor-SS patient encounters has significantly decreased (by 50%) yearly over the last decade.}, keywords = {Hungary; Sjogren's Syndrome; sicca syndrome}, year = {2023}, eissn = {1601-0825}, pages = {2756-2764}, orcid-numbers = {Dézsi, Anna/0000-0001-5139-1580; Erdei, Csilla/0000-0003-1110-9645; Demeter, Tamás/0000-0003-3385-3344; Kovács, Alexandra/0000-0001-5831-4983; Nagy, Gábor/0000-0001-5510-7903; Mensch, Károly/0000-0002-7764-1944; Németh, Orsolya/0000-0002-4714-1463; Hermann, Péter/0000-0002-9148-0139; Tóth, György/0000-0001-7544-3971; Füst, Ágnes/0000-0002-5725-4461; Kiss, Emese/0000-0002-5399-2379; Kőhidai, László/0000-0002-9002-0296; Zalatnai, Attila/0000-0001-6334-8336; Márton, Krisztina/0000-0002-6525-2511} } @article{MTMT:32568337, title = {A Study of Prognostic Factors in Young Patients With Non-HPV Oral Cancer in Central Europe}, url = {https://m2.mtmt.hu/api/publication/32568337}, author = {Csurgay, Katalin and Zalatnai, Attila and Benczik, Márta and Csomó, Krisztián Benedek and Horváth, Ferenc and Lőrincz, Ádám and Komlós, György and Németh, Zsolt}, doi = {10.3389/pore.2021.1609991}, journal-iso = {PATHOL ONCOL RES}, journal = {PATHOLOGY AND ONCOLOGY RESEARCH}, volume = {27}, unique-id = {32568337}, issn = {1219-4956}, abstract = {The etiological factors of squamous cell carcinomas of the head and neck have been well known for a long time. It is also well known that the incidence of oral cancer diagnosed in younger patients is on the rise. Due to the young age of these patients, the increase in the number of these cases and the fact that many of them neither smoke nor drink alcohol it has been suggested that other factors might be at play in the carcinogenesis of oral cancer. Thus, along the classic etiological factors of smoking and alcohol abuse certain molecular marker anomalies and the human papilloma virus (HPV) have emerged as potential factors. The aim of the present study is to verify the potential prognostic factors and to map the differences in biomarker expression between the young and the old patient groups. In the present study the immunohistochemical profile of samples obtained from oral squamous cell carcinomas was studied and compared with various clinico-pathological parameters. In 88 samples the expressions of p16, p53, Ki67, EGFR were studied with a tissue microarray technique under standard reaction conditions as well as the detection and typing of HPV infection with the Full Spectrum HPV DNA method. The biomarker expression profile of young patients with oral squamous cell carcinoma was compared to that of older patients (above 50). A significant difference was found between the immunohistochemical profile of the young and old patient groups in p16, Ki67 expression. The overall survival and progression free survival were influenced by p16 expression in young age.}, year = {2021}, eissn = {1532-2807}, orcid-numbers = {Csurgay, Katalin/0000-0003-0230-2793; Zalatnai, Attila/0000-0001-6334-8336; Csomó, Krisztián Benedek/0000-0002-3749-6391; Horváth, Ferenc/0000-0003-4265-825X; Komlós, György/0000-0002-1305-6471; Németh, Zsolt/0000-0002-0231-7437} } @article{MTMT:32007893, title = {Histopathological Sample Preparation with Unique Biopsy Forceps in The Diagnosis of Sjögren’s Syndrome}, url = {https://m2.mtmt.hu/api/publication/32007893}, author = {Dézsi, Anna and Erdei, Csilla and Demeter, Tamás and Kovács, Alexandra and Márton, Krisztina}, doi = {10.17303/jdoh.2021.8.103}, journal-iso = {J DENT ORAL HEALTH}, journal = {JOURNAL OF DENTISTRY & ORAL HEALTH}, volume = {8}, unique-id = {32007893}, issn = {2332-4856}, year = {2021}, orcid-numbers = {Dézsi, Anna/0000-0001-5139-1580; Erdei, Csilla/0000-0003-1110-9645; Demeter, Tamás/0000-0003-3385-3344; Kovács, Alexandra/0000-0001-5831-4983; Márton, Krisztina/0000-0002-6525-2511} } @article{MTMT:30337024, title = {PCR Technique Assisting the Early Diagnosis of Human Papillomavirus. A retrospective clinical study}, url = {https://m2.mtmt.hu/api/publication/30337024}, author = {Mensch, Károly and Szarka, Krisztina Zsuzsanna and Mensch, H and Dobai, Adrienn and Magyar, Z and Pacurar, M and Vartolomei, AC and Manuc, D and Dobó-Nagy, Csaba}, doi = {10.37358/rc.18.10.6624}, journal-iso = {REV CHIM-BUCHAREST}, journal = {REVISTA DE CHIMIE}, volume = {69}, unique-id = {30337024}, issn = {0034-7752}, year = {2018}, pages = {2781-2787}, orcid-numbers = {Mensch, Károly/0000-0002-7764-1944; Dobai, Adrienn/0000-0003-1643-0649; Dobó-Nagy, Csaba/0000-0001-9530-7926} } @article{MTMT:1342316, title = {Epstein-Barr virus prevalence in oral squamous cell cancer and in potentially malignant oral disorders in an eastern Hungarian population}, url = {https://m2.mtmt.hu/api/publication/1342316}, author = {Kis, Andrea and Fehér, Enikő and Gáll, Tamás and Tar, Ildikó and Boda, Róbert and D. Tóth, Etelka and Méhes, Gábor and Gergely, Lajos and Szarka, Krisztina Zsuzsanna}, doi = {10.1111/j.1600-0722.2009.00660.x}, journal-iso = {EUR J ORAL SCI}, journal = {EUROPEAN JOURNAL OF ORAL SCIENCES}, volume = {117}, unique-id = {1342316}, issn = {0909-8836}, year = {2009}, eissn = {1600-0722}, pages = {536-540} }