https://m2.mtmt.hu/ hun 2026-07-19 04:50 true true 1 3 3 1 100 1 3 DESC publishedYear false ASC firstAuthor true ASC title true JournalArticle 30482956 VALIDATED true 0 false 2026-05-19T03:18:46.501+0000 2021-10-14T02:12:55.415+0000 2019-03-01T03:30:17.154+0000 true 10020744 Kiss Balázs /api/author/10020744 Author true 10020744 2020-04-28T09:05:46.709+0000 true 10026258 Nemesvári Zoltánné /api/admin/10026258 Admin true 10026258 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Schick, Revital Functional abnormalities in induced Pluripotent Stem Cell-derived cardiomyocytes generated from titin-mutated patients with dilated cardiomyopathy true true /api/journal/10007440 REVIEWED true false 10007440 false 10007440 true 1932-6203 Journal FOREIGN 13 10 e0205719 e0205719 2018 Aims Dilated cardiomyopathy (DCM), a myocardial disorder that can result in progressive heart failure and arrhythmias, is defined by ventricular chamber enlargement and dilatation, and systolic dysfunction. Despite extensive research, the pathological mechanisms of DCM are unclear mainly due to numerous mutations in different gene families resulting in the same outcome-decreased ventricular function. Titin (TTN) a giant protein, expressed in cardiac and skeletal muscles, is an important part of the sarcomere, and thus TTN mutations are the most common cause of adult DCM. To decipher the basis for the cardiac pathology in titin-mutated patients, we investigated the hypothesis that induced Pluripotent Stem Cell (iPSC)-derived cardiomyocytes (iPSC-CM) generated from patients, recapitulate the disease phenotype. The hypothesis was tested by 3 Aims: (1) Investigate key features of the excitation-contraction-coupling machinery; (2) Investigate the responsiveness to positive inotropic interventions; (3) Investigate the proteome profile of the AuP cardiomyocytes using mass-spectrometry (MS). Methods and results iPSC were generated from the patients' skin fibroblasts. The major findings were: (1) Sarcomeric organization analysis in mutated iPSC-CM showed defects in assembly and maintenance of sarcomeric structure. (2) Mutated iPSC-CM exhibited diminished inotropic and lusitropic responses to beta-adrenergic stimulation with isoproterenol, increased [Ca2+](out) and angiotensin-II. Additionally, mutated iPSC-CM displayed prolonged recovery in response to caffeine. These findings may result from defective or lack of interactions of the sarcomeric components with titin through its kinase domain which is absent in the mutated cells. Conclusions These findings show that the mutated cardiomyocytes from DCM patients recapitulate abnormalities of the inherited cardiomyopathies, expressed as blunted inotropic response. 2019 true true true false false GOLD 2026-05-19 true https://doi.org/10.1371/journal.pone.0205719 36 0 36 30 1 36 36 36 24 36 36 30 30 30 6 0 36 30 36 30 0 3 3 Q1 A false false false false 2020-04-16T15:03:30.457+0000 Biokémiai Intézet (SZTE / SZAOK) 1 6 1 20 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 85685934 /api/authorship/85685934 1 0.05 true false Schick Revital true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685935 /api/authorship/85685935 2 0.05 true false Mekies Lucy N. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685936 /api/authorship/85685936 3 0.05 false false Shemer Yuval true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685937 /api/authorship/85685937 4 0.05 false false Eisen Binyamin true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685938 /api/authorship/85685938 5 0.05 false false Hallas Tova true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685939 /api/authorship/85685939 6 0.05 false false Ben Jehuda Ronen true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685940 /api/authorship/85685940 7 0.05 false false Ben-Ari Meital true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685941 /api/authorship/85685941 8 0.05 false false Author 10056771 /api/author/10056771 Szántai Ágnes true 10056771 true Szantai Agnes true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685942 /api/authorship/85685942 9 0.05 false false Willi Lubna true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685943 /api/authorship/85685943 10 0.05 false false Shulman Rita true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685944 /api/authorship/85685944 11 0.05 false false Gramlich Michael true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685945 /api/authorship/85685945 12 0.05 false false Pane Luna Simona true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685946 /api/authorship/85685946 13 0.05 false false My Ilaria true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685947 /api/authorship/85685947 14 0.05 false false Freimark Dov true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685948 /api/authorship/85685948 15 0.05 false false Murgia Marta true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685949 /api/authorship/85685949 16 0.05 false false Santamaria Gianluca true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685950 /api/authorship/85685950 17 0.05 false false Gherghiceanu Mihaela true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685951 /api/authorship/85685951 18 0.05 false false Arad Michael true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685952 /api/authorship/85685952 19 0.05 false false Moretti Alessandra true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 85685953 /api/authorship/85685953 20 0.05 false true true Binah Ofer true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 15276827 /api/publicationidentifier/15276827 PlainSource 6 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SjrRating 10976076 /api/sjrrating/10976076 34 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1101 /api/classificationexternal/1101 true 1101 true Q1 DIRECT true true /api/publication/30482956 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Schick Revital </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Mekies Lucy N.<sup>*</sup> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Shemer Yuval </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Eisen Binyamin </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hallas Tova </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ben Jehuda Ronen </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ben-Ari Meital </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10056771"><a href="/gui2/?type=authors&mode=browse&sel=10056771" target="_blank">Szantai Agnes (<span class="authorship-author-name">Szántai Ágnes</span> <span class="authorAux-mtmt"> orvostudományok</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Biokémiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Willi Lubna </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Shulman Rita </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gramlich Michael </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Pane Luna Simona </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >My Ilaria </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Freimark Dov </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Murgia Marta </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Santamaria Gianluca </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gherghiceanu Mihaela </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Arad Michael </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Moretti Alessandra </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Binah Ofer ✉ </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;30482956" target="_blank">Functional abnormalities in induced Pluripotent Stem Cell-derived cardiomyocytes generated from titin-mutated patients with dilated cardiomyopathy</a></div> <div> <span class="journal-title">PLOS ONE</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/1932-6203">1932-6203</a>)</span>: <span class="journal-volume">13</span> <span class="journal-issue">10</span> <span class="page"> Paper e0205719. </span> <span class="year">(2018)</span> </div> <div class="pub-footer"> <span class="language" 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The thick filament is of a precisely controlled length, defining thereby the force level that muscles generate and how this force varies with muscle length. It has been speculated that the mechanism by which thick filament length is controlled involves the giant protein titin, but no conclusive support for this hypothesis exists. Here we show that in a mouse model in which we deleted two of titin's C-zone super-repeats, thick filament length is reduced in cardiac and skeletal muscles. In addition, functional studies reveal reduced force generation and a dilated cardiomyopathy (DCM) phenotype. Thus, regulation of thick filament length depends on titin and is critical for maintaining muscle health. 2017 529377 true true true false true false GOLD 2026-05-18 true https://doi.org/10.1038/s41467-017-01144-9 87 0 86 67 7 85 86 85 78 86 86 67 67 67 20 0 87 67 86 67 0 6 6 D1 A nemzetközi false 10020744 false false false 2018-01-21T02:39:21.000+0000 2017-10-23T01:39:21.000+0000 1 11 0 8 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 9425458 /api/authorship/9425458 1 0.125 true false Tonino P true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 26950305 true PersonAuthorship 9425459 /api/authorship/9425459 2 0.125 true false Author 10020744 /api/author/10020744 Kiss Balázs true 10020744 true Kiss B true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 26950304 true PersonAuthorship 9425460 /api/authorship/9425460 3 0.125 false false Strom J true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 26950303 true PersonAuthorship 9425461 /api/authorship/9425461 4 0.125 false false Methawasin M true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 26950302 true PersonAuthorship 9425462 /api/authorship/9425462 5 0.125 false false Smith JE rd true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 26950301 true PersonAuthorship 9425463 /api/authorship/9425463 6 0.125 false false Kolb J true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 26950300 true PersonAuthorship 9425464 /api/authorship/9425464 7 0.125 false false Labeit S true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 26950299 true PersonAuthorship 9425465 /api/authorship/9425465 8 0.125 false true Granzier H true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 26950298 true PublicationIdentifier 1237878 /api/publicationidentifier/1237878 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1038/s41467-017-01144-9 https://doi.org/10.1038/s41467-017-01144-9 false 1656801 true PublicationIdentifier 1237876 /api/publicationidentifier/1237876 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true false IDENTICAL 000413197100001 https://www.webofscience.com/wos/woscc/full-record/000413197100001 false 1709064 true PublicationIdentifier 1237877 /api/publicationidentifier/1237877 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true false IDENTICAL 85031899890 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85031899890 false 1709065 true PublicationIdentifier 1237879 /api/publicationidentifier/1237879 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true false IDENTICAL 29051486 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=29051486&dopt=Abstract false 1656802 true Classification 10154 /api/classification/10154 true true MtaRating 11551153 /api/mtarating/11551153 RatingType 10010 /api/ratingtype/10010 RegTB Institute 14100 /api/institute/14100 0 false true false Regionális Tudományok Bizottsága Committee on Regional Studies true 14100 true true true A nemzetközi false true SjrRating 10682589 /api/sjrrating/10682589 11 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1301 /api/classificationexternal/1301 true 1301 true D1 DIRECT true true /api/publication/3282237 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Tonino P </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10020744"><a href="/gui2/?type=authors&mode=browse&sel=10020744" target="_blank">Kiss B<sup>*</sup> (<span class="authorship-author-name">Kiss Balázs</span> <span class="authorAux-mtmt"> Biofizika</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Strom J </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Methawasin M </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Smith JE rd </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kolb J </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Labeit S </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Granzier H </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;3282237" target="_blank">The giant protein titin regulates the length of the striated muscle thick filament</a></div> <div> <span class="journal-title">NATURE COMMUNICATIONS</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2041-1723">2041-1723</a>)</span>: <span class="journal-volume">8</span> <span class="journal-issue">1</span> <span class="page"> Paper 1041. 11 p. </span> <span class="year">(2017)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1038/s41467-017-01144-9" target="_blank" href="https://doi.org/10.1038/s41467-017-01144-9"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000413197100001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000413197100001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85031899890" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85031899890"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="29051486" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=29051486&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Chemistry (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Physics and Astronomy (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Regionális Tudományok Bizottsága IXGJO RTB [1901-]&nbsp;&nbsp;&nbsp;A nemzetközi</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 87</span> | Független: 67 | Függő: 20 | Nem jelölt: 0 | WoS jelölt: 85 | Scopus jelölt:&nbsp;78 | WoS/Scopus jelölt:&nbsp;86 | DOI jelölt:&nbsp;86 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;3282237&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 6 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 3282237</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 3282237</span> | Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Utolsó módosítás: 2023.09.02. 17:04 Milánkovics Róbert (PTE ÁOK admin 4) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: * Megosztott szerzőség</pre> </div></div> JournalArticle 1322327 VALIDATED true 0 2014-05-25T15:50:30.000+0000 false 1322327 2026-05-13T20:47:21.190+0000 2025-09-12T16:21:37.916+0000 2010-02-27T17:29:48.000+0000 true 10003432 Trombitás Károly /api/author/10003432 Author true 10003432 2025-09-12T16:21:38.291+0000 2025-09-12T16:21:38.291+0000 2020-06-15T13:21:07.397+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin true 10039043 2021-03-19T09:49:17.558+0000 true 10022707 Najbauerné Bacsics Zsuzsanna /api/admin/10022707 Admin true 10022707 Admin 10065569 /api/admin/10065569 Pécsi Éva true true 2021-12-07T20:32:00.231+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Centner, T Molecular tools for the study of titin's differential expression true true /api/journal/15628 REVIEWED true false 15628 false 15628 true 0065-2598 2214-8019 Journal FOREIGN 481 35 52 35 18 2000 Although vertebrate genomes appear to contain only one titin gene, a large variety of quite distinct titin isoforms are expressed in striated muscle tissues. The isoforms appear to be generated by a series of complex, not yet fully characterized differential splicing mechanisms. Here, we provide an overview of the titin-specific antibodies that have been raised by our laboratory to study individual differentially expressed isoforms of titin. The staining patterns obtained in different tissues will contribute to the identification of both the particular titin isoforms that are expressed in the different tissues, as well as their intracellular distributions. In addition, antibodies to titin that are available are rapidly allowing for the refinement of our knowledge of titin's elastic spring properties. Knowledge of the nature and structure of vertebrate titins that may also be expressed in nonmuscle tissues may be broadened using these antibodies. 2010 true true true false false NONE 2026-05-13 false 21 0 21 4 1 21 18 21 17 21 21 4 4 4 17 0 21 4 21 4 0 4 4 Q2 false false false false 2013-05-24T18:18:00.000+0000 2013-02-23T19:18:00.000+0000 1 7 0 9 0 true 10065569 Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 965369 /api/authorship/965369 1 0.11111111 true false Centner T true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 11040365 true PersonAuthorship 965370 /api/authorship/965370 2 0.11111111 false false Fougerousse F true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 11040364 true PersonAuthorship 965371 /api/authorship/965371 3 0.11111111 false false Freiburg A true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 11040363 true PersonAuthorship 965372 /api/authorship/965372 4 0.11111111 false false Witt C true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 11040362 true PersonAuthorship 965373 /api/authorship/965373 5 0.11111111 false false Beckmann JS true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 11040361 true PersonAuthorship 965374 /api/authorship/965374 6 0.11111111 false false Granzier H true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 11040360 true PersonAuthorship 965375 /api/authorship/965375 7 0.11111111 false false Author 10003432 /api/author/10003432 Trombitás Károly true 10003432 true Trombitas K true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 11040359 true PersonAuthorship 965376 /api/authorship/965376 8 0.11111111 false false Gregorio CC true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 11040358 true PersonAuthorship 965377 /api/authorship/965377 9 0.11111111 false true Labeit S true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 11040357 true PublicationIdentifier 29833057 /api/publicationidentifier/29833057 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true 10.1007/978-1-4615-4267-4_3 https://doi.org/10.1007/978-1-4615-4267-4_3 false true PublicationIdentifier 266177 /api/publicationidentifier/266177 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true false DIFFERENT 000167396000003 https://www.webofscience.com/wos/woscc/full-record/000167396000003 false 137405 true PublicationIdentifier 2871934 /api/publicationidentifier/2871934 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true NO 0034471816 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-0034471816 false 12395843 true PublicationIdentifier 14705387 /api/publicationidentifier/14705387 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true NO 10987065 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10987065&dopt=Abstract false 15438356 true SjrRating 6128216 /api/sjrrating/6128216 46 0.49 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1301 /api/classificationexternal/1301 true 1301 true Q2 DIRECT true 6128216 true /api/publication/1322327 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Centner T </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Fougerousse F </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Freiburg A </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Witt C </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Beckmann JS </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Granzier H </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10003432"><a href="/gui2/?type=authors&mode=browse&sel=10003432" target="_blank">Trombitas K (<span class="authorship-author-name">Trombitás Károly</span> <span class="authorAux-mtmt"> Izomkutatás</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gregorio CC </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Labeit S </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;1322327" target="_blank">Molecular tools for the study of titin's differential expression</a></div> <div> <span class="journal-title">ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0065-2598">0065-2598</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2214-8019">2214-8019</a>)</span>: <span class="journal-volume">481</span> <span class="page"> pp 35-52 </span> <span class="year">(2000)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:black" title="10.1007/978-1-4615-4267-4_3" target="_blank" href="https://doi.org/10.1007/978-1-4615-4267-4_3"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000167396000003" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000167396000003"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="0034471816" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-0034471816"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="10987065" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10987065&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 21</span> | Független: 4 | Függő: 17 | Nem jelölt: 0 | WoS jelölt: 21 | Scopus jelölt:&nbsp;17 | WoS/Scopus jelölt:&nbsp;21 | DOI jelölt:&nbsp;18 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1322327&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 4 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 1322327</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 1322327</span> | Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS</span> </div> <div class="lastModified">Utolsó módosítás: 2025.09.12. 18:21 Vasvari Lilian (MTMT Központ, admin) </div> <div class="lockedBy">Központi kezelésű 2021.12.07. 21:32 Pécsi Éva (MTMT Közp 2,3, admin) </div> </div></div>