@article{MTMT:33051869, title = {Screening for Myocardial Injury after Mild SARS-CoV-2 Infection with Advanced Transthoracic Echocardiography Modalities}, url = {https://m2.mtmt.hu/api/publication/33051869}, author = {Rácz, Gergely and Takács, Hedvig and Kormányos, Árpád and Polestyuk, Bianka Petra and Borbás, János and Gyenes, Nándor and Schvartz, Noémi and Németh, Gergely and Kincses, Zsigmond Tamás and Sepp, Róbert and Nagy, Viktória}, doi = {10.3390/diagnostics12081941}, journal-iso = {DIAGNOSTICS}, journal = {DIAGNOSTICS}, volume = {12}, unique-id = {33051869}, issn = {2075-4418}, abstract = {Although the clinical manifestations of SARS-CoV-2 viral infection affect mainly the respiratory system, cardiac complications are common and are associated with increased morbidity and mortality. While echocardiographic alterations indicating myocardial involvement are widely reported in patients hospitalized for acute COVID-19 infection, much fewer data available in non-hospitalized, mildly symptomatic COVID-19 patients. In our work, we aimed to investigate subclinical cardiac alterations characterized by parameters provided by advanced echocardiographic techniques following mild SARS-CoV-2 viral infection. A total of 86 patients (30 males, age: 39.5 ± 13.0 yrs) were assessed 59 ± 33 days after mild SARS-CoV-2 viral infection (requiring no hospital or <5 days in-hospital treatment) by advanced echocardiographic examination including 2-dimensional (2D) speckle tracking echocardiography and non-invasive myocardial work analysis, and were compared to an age-and sex-matched control group. Altogether, variables from eleven echocardiographic categories representing morphological or functional echocardiographic parameters showed statistical difference between the post-COVID patient group and the control group. The magnitude of change was subtle or mild in the case of these parameters, ranging from 1–11.7% of relative change. Among the parameters, global longitudinal strain [−20.3 (−21.1–−19.0) vs. −19.1 (−20.4–−17.6) %; p = 0.0007], global myocardial work index [1975 (1789–2105) vs. 1829 (1656–2057) Hgmm%; p = 0.007] and right ventricular free wall strain values (−26.6 ± 3.80 vs. −23.8 ± 4.0%; p = 0.0003) showed the most significant differences between the two groups. Subclinical cardiac alterations are present following even mild SARS-CoV-2 viral infection. These more subtle alterations are difficult to detect by routine echocardiography. Extended protocols, involving speckle-tracking echocardiography, non-invasive measurement of cardiac hemodynamics, and possibly myocardial work are necessary for detection and adequate follow-up.}, year = {2022}, eissn = {2075-4418}, orcid-numbers = {Kormányos, Árpád/0000-0002-7052-2184; Kincses, Zsigmond Tamás/0000-0002-1442-4475; Sepp, Róbert/0000-0003-4964-1661} } @article{MTMT:32804523, title = {The Genetic Architecture of Hypertrophic Cardiomyopathy in Hungary: Analysis of 242 Patients with a Panel of 98 Genes}, url = {https://m2.mtmt.hu/api/publication/32804523}, author = {Sepp, Róbert and Hategan, Lídia and Csányi, Beáta and Borbás, János and Tringer, Annamária and Pálinkás, Eszter Dalma and Nagy, Viktória and Takács, Hedvig and Latinovics, Dóra and Nyolczas, Noémi and Pálinkás, Attila and Faludi, Réka and Rábai, Miklós and Szabó, Gábor Tamás and Czuriga, Dániel and Balogh, László and Halmosi, Róbert and Borbély, Attila and Habon, Tamás and Hegedűs, Zoltán and Nagy, István}, doi = {10.3390/diagnostics12051132}, journal-iso = {DIAGNOSTICS}, journal = {DIAGNOSTICS}, volume = {12}, unique-id = {32804523}, issn = {2075-4418}, year = {2022}, eissn = {2075-4418}, orcid-numbers = {Sepp, Róbert/0000-0003-4964-1661; Pálinkás, Eszter Dalma/0000-0003-0713-3909; Nyolczas, Noémi/0000-0001-9466-0939; Szabó, Gábor Tamás/0000-0001-9880-0425; Czuriga, Dániel/0000-0002-6972-0781; Habon, Tamás/0000-0002-4816-857X} } @article{MTMT:3110752, title = {Identification of a Novel GLA Gene Mutation, p.Ile239Met, in Fabry Disease with a Predominant Cardiac Phenotype. [case report]}, url = {https://m2.mtmt.hu/api/publication/3110752}, author = {Csányi, Beáta and Hategan, Lídia and Nagy, Viktória and Obál, Izabella and Varga, Edina Tímea and Borbás, János and Tringer, Annamária and Sabrina, Eichler and Forster, Tamás and Arndt, Rolfs and Sepp, Róbert}, doi = {10.1536/ihj.16-361}, journal-iso = {INT HEART J}, journal = {INTERNATIONAL HEART JOURNAL}, volume = {58}, unique-id = {3110752}, issn = {1349-2365}, year = {2017}, eissn = {1349-3299}, pages = {454-458}, orcid-numbers = {Varga, Edina Tímea/0000-0002-9365-3689; Forster, Tamás/0000-0003-3311-6475; Sepp, Róbert/0000-0003-4964-1661} } @article{MTMT:3026076, title = {Identification of two novel LAMP2 gene mutations in Danon disease}, url = {https://m2.mtmt.hu/api/publication/3026076}, author = {Csányi, Beáta and Popoiu, A and Hategan, Lídia and Hegedűs, Zoltán and Nagy, Viktória and Rácz, Katalin Róza and Hőgye, Márta and Sághy, László and Iványi, Béla and Csanády, Miklós and Forster, Tamás and Sepp, Róbert}, doi = {10.1016/j.cjca.2016.02.071}, journal-iso = {CAN J CARDIOL}, journal = {CANADIAN JOURNAL OF CARDIOLOGY}, volume = {32}, unique-id = {3026076}, issn = {0828-282X}, year = {2016}, eissn = {1916-7075}, pages = {1355.e23-1355.e30}, orcid-numbers = {Forster, Tamás/0000-0003-3311-6475; Sepp, Róbert/0000-0003-4964-1661} } @article{MTMT:1745328, title = {The Gln1233ter mutation of the myosin binding protein C gene: Causative mutation or innocent polymorphism in patients with hypertrophic cardiomyopathy?}, url = {https://m2.mtmt.hu/api/publication/1745328}, author = {Tóth, Tímea and Nagy, Viktória and Faludi, Réka and Csanády, Miklós and Nemes, Attila and Simor, Tamás and Forster, Tamás and Sepp, Róbert}, doi = {10.1016/j.ijcard.2011.09.062}, journal-iso = {INT J CARDIOL}, journal = {INTERNATIONAL JOURNAL OF CARDIOLOGY}, volume = {153}, unique-id = {1745328}, issn = {0167-5273}, year = {2011}, eissn = {1874-1754}, pages = {216-219}, orcid-numbers = {Nemes, Attila/0000-0002-7570-6214; Forster, Tamás/0000-0003-3311-6475; Sepp, Róbert/0000-0003-4964-1661} }