TY - JOUR AU - Yun, C AU - Kim, TY AU - Zhang, T AU - Kim, Y AU - Lee, SY AU - Park, S AU - Friedler, Ferenc AU - Bertók, Botond TI - Determination of the thermodynamically dominant metabolic pathways JF - INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH J2 - IND ENG CHEM RES VL - 52 PY - 2013 IS - 1 SP - 222 EP - 229 PG - 8 SN - 0888-5885 DO - 10.1021/ie300652h UR - https://m2.mtmt.hu/api/publication/2418290 ID - 2418290 N1 - Department of Chemical and Biomolecular Engineering, KAIST, Daejeon 305-701, South Korea Department of Chemical Engineering, Kansas State University, Manhattan, KS 66506, United States Department of Computer Science, University of Pannonia, Egyetem u. 10, H-8200 Veszprem, Hungary Department of Thermal Systems, Korea Institute of Machinery and Materials, Daejeon 305-343, South Korea Doosan Heavy Industries and Construction, Daejeon 305-348, South Korea Western Research Institute, Laramie, WY 82072, United States Cited By :6 Export Date: 16 October 2023 CODEN: IECRE Correspondence Address: Park, S.; Department of Chemical and Biomolecular Engineering, , Daejeon 305-701, South Korea; email: sunwon@kaist.ac.kr AB - An effective strategy comprising two phases is proposed to determine the thermodynamically dominant pathways in a metabolic network of a given phenotype, involving several metabolic reactions. In the first phase, stoichiometrically feasible metabolic pathways are exhaustively identified through the flux balance analysis and the graph-theoretic method based on P-graphs. In the second phase, thermodynamically dominant pathways are selected from these stoichiometrically feasible metabolic pathways on the basis of the Gibbs free energy change of reaction. The proposed strategy's efficacy is demonstrated by applying it to two E. coli models: one is for maximal acetate and ethanol production, and the other is for maximalpoly(3-hydroxybutyrate) production. © 2012 American Chemical Society. LA - English DB - MTMT ER - TY - JOUR AU - Fan, L T AU - Lin, Y -C AU - Shafie, S AU - Bertók, Botond AU - Friedler, Ferenc TI - Exhaustive identification of feasible pathways of the reaction catalyzed by a catalyst with multiactive sites via a highly effective graph-theoretic algorithm: Application to ethylene hydrogenation JF - INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH J2 - IND ENG CHEM RES VL - 51 PY - 2012 IS - 6 SP - 2548 EP - 2552 PG - 5 SN - 0888-5885 DO - 10.1021/ie200718w UR - https://m2.mtmt.hu/api/publication/1892675 ID - 1892675 N1 - Department of Chemical Engineering, Kansas State University, Manhattan, KS 66506-5102, United States Department of Chemical Engineering and Materials Science, Yuan Ze University, Chungli, Taoyuan, 32003, Taiwan Department of Computer Science and Systems Technology, University of Pannonia, Egyetem u.10, H-8200 Veszprém, Hungary Cited By :10 Export Date: 16 October 2023 CODEN: IECRE Correspondence Address: Fan, L.T.; Department of Chemical Engineering, , Manhattan, KS 66506-5102, United States; email: fan@ksu.edu AB - Hitherto, no attempt has been made to identify exhaustively feasible pathways for any mechanism of a given reaction catalyzed by a catalyst with multiactive sites. Two stoichiometically exact and definitely feasible mechanisms have been proposed to date for the hydrogenation of ethylene to ethane on biactive-site or triactive-site platinum catalysts. One comprises seven elementary reactions, and the other comprises eight elementary reactions; nevertheless, both mechanisms involve competitive as well as noncompetitive adsorption. Any of these mechanisms gives rise to a multitude of feasible catalytic pathways. The present work exhaustively identifies such feasible pathways by resorting to the inordinately efficient graph-theoretic algorithm based on P- graphs (process graphs). The efficacy of this algorithm has been amply demonstrated by successfully deploying it for several catalysts with single-active sites, but has never been deployed for catalysts with multiactive sites as in the current work. The availability of exhaustively identified feasible pathways for both mechanisms renders it possible to stipulate that the hydrogenation of chemisorbed chemisorbed C 2H 5 is the rate-controlling step: This step is contained in either mechanism. © 2012 American Chemical Society. LA - English DB - MTMT ER - TY - JOUR AU - Garcia Ojeda, Juan Carlos AU - Bertók, Botond AU - Friedler, Ferenc TI - Planning Evacuation Routes with the P-graph Framework JF - CHEMICAL ENGINEERING TRANSACTIONS J2 - CHEM ENG TR VL - 29 PY - 2012 IS - 2 SP - 1531 EP - 1536 PG - 6 SN - 1974-9791 DO - 10.3303/CET1229256 UR - https://m2.mtmt.hu/api/publication/2060145 ID - 2060145 N1 - Department of Systems Engineering, Autonomous University of Bucaramanga, Av. 42 No 48-11, Bucaramanga, Colombia Department of Computer Science and Systems Technology, University of Pannonia, Egyetem u. 10, Veszprém, H-8200, Hungary Cited By :28 Export Date: 16 October 2023 Correspondence Address: Garcia-Ojeda, J.C.; Department of Systems Engineering, Av. 42 No 48-11, Bucaramanga, Colombia; email: jgarciao@unab.edu.co LA - English DB - MTMT ER - TY - JOUR AU - Kalauz, Károly AU - Süle, Zoltán AU - Bertók, Botond AU - Friedler, Ferenc AU - Fan, L T TI - Extending Process-Network Synthesis Algorithms with Time Bounds for Supply Network Design JF - CHEMICAL ENGINEERING TRANSACTIONS J2 - CHEM ENG TR VL - 29 PY - 2012 IS - 1 SP - 259 EP - 264 PG - 6 SN - 1974-9791 DO - 10.3303/CET1229044 UR - https://m2.mtmt.hu/api/publication/2060125 ID - 2060125 N1 - University of Pannonia, Department of Computer Science and Systems Technology, Egyetem u. 10, H-8200 Veszprém, Hungary Kansas State University, Department of Chemical Engineering, KS 66506 Manhattan, United States Cited By :16 Export Date: 16 October 2023 Correspondence Address: Bertók, B.; University of Pannonia, Egyetem u. 10, H-8200 Veszprém, Hungary; email: bertok@dcs.uni-pannon.hu LA - English DB - MTMT ER - TY - JOUR AU - Barany, M. AU - Bertók, Botond AU - Kovács, Zoltán AU - Friedler, Ferenc AU - Fan, L.T. TI - Optimization software for solving vehicle assignment problems to minimize cost and environmental impact of transportation JF - CHEMICAL ENGINEERING TRANSACTIONS J2 - CHEM ENG TR VL - 21 PY - 2010 SP - 499 EP - 504 PG - 6 SN - 9788895608051 SN - 1974-9791 DO - 10.3303/CET1021084 UR - https://m2.mtmt.hu/api/publication/34197830 ID - 34197830 N1 - Department of Computer Science and Systems Techonolgy, FIT, University of Pannonia, Egyetem u. 10, 8200 Veszprém, Hungary Department of Chemical Engineering, Kansas State University, United States Cited By :17 Export Date: 16 October 2023 Correspondence Address: Friedler, F.; Department of Computer Science and Systems Techonolgy, Egyetem u. 10, 8200 Veszprém, Hungary; email: friedler@dcs.uni-pannon.hu AB - A method and software are proposed for optimal assignment of vehicles to transportation tasks in terms of total cost and emission. Each task is given by a set of attributes to be taken into account in the assignment; and this is also the case for each vehicle. The overall mileage is calculated as the sum of the lengths of all the routes to be travelled during, before, after, and between the tasks (Deaulniers et al., 1998; Baita et al., 2000). Cost and emission are assigned to the mileages of each vehicle type. Copyright © 2010 AIDIC Servizi S.r.l. LA - English DB - MTMT ER - TY - BOOK AU - Klemeš, Jiri Jaromir AU - Friedler, Ferenc AU - I, Bulatov AU - Varbanov, Petar TI - Sustainability in the Process Industry. Integration and Optimization TS - Integration and Optimization T3 - Green Manufacturing & Systems Engineering ET - 0 PB - McGraw-Hill CY - New York, New York PY - 2010 SP - 384 SN - 9780071605540 UR - https://m2.mtmt.hu/api/publication/1691867 ID - 1691867 LA - English DB - MTMT ER - TY - BOOK AU - Temesi, József TI - A döntéselmélet alapjai ET - 0 PB - Aula Kiadó CY - Budapest PY - 2002 SP - 169 SN - 9639345644 UR - https://m2.mtmt.hu/api/publication/2295364 ID - 2295364 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Kovács, Zoltán AU - Ercsey, Zsolt AU - Friedler, Ferenc AU - Fan, L T TI - Separation-network synthesis: global optimum through rigorous super-structure JF - COMPUTERS & CHEMICAL ENGINEERING J2 - COMPUT CHEM ENG VL - 24 PY - 2000 IS - 8 SP - 1881 EP - 1900 PG - 20 SN - 0098-1354 DO - 10.1016/S0098-1354(00)00568-8 UR - https://m2.mtmt.hu/api/publication/1044836 ID - 1044836 N1 - Department of Computer Science, University of Veszprém, Egyetem u. 10, Veszprém, H-8200, Hungary Department of Chemical Engineering, Kansas State University, Manhattan, KS 66506, United States Department of Computer Science, József Attila University, Árpád tér 2, Szeged, H-6720, Hungary Cited By :40 Export Date: 16 October 2023 CODEN: CCEND Correspondence Address: Friedler, F.; Department of Computer Science, , Veszprem, Egyetem u. 10., H-8200, Hungary; email: friedler@dcs.vein.hu Funding details: Hungarian Science Foundation, T-014212 Funding text 1: This research was partially supported by the Hungarian Science Foundation Grant No. T-014212. This is contribution #99-224-J, Department of Chemical Engineering, Kansas Agricultural Experiment Station, Kansas State University, Manhattan, KS 66506. LA - English DB - MTMT ER - TY - JOUR AU - Kovács, Zoltán AU - Ercsey, Zsolt AU - Friedler, Ferenc AU - Fan, LT TI - Exact super-structure for the synthesis of separation-networks with multiple feed-streams and sharp separators JF - COMPUTERS & CHEMICAL ENGINEERING J2 - COMPUT CHEM ENG VL - 23 PY - 1999 IS - Supplement 1 SP - S1007 EP - S1010 SN - 0098-1354 DO - 10.1016/S0098-1354(99)80238-5 UR - https://m2.mtmt.hu/api/publication/1774307 ID - 1774307 N1 - European Symposium on Computer Aided Process Engineering LA - English DB - MTMT ER - TY - JOUR AU - Friedler, Ferenc AU - Tarján, Klára AU - Huang, Y W AU - Fan, L T TI - Combinatorial Algorithms for Process Synthesis JF - COMPUTERS & CHEMICAL ENGINEERING J2 - COMPUT CHEM ENG VL - 16 PY - 1992 SP - S313 EP - S320 SN - 0098-1354 DO - 10.1016/S0098-1354(09)80037-9 UR - https://m2.mtmt.hu/api/publication/1044848 ID - 1044848 N1 - Cited By :204 Export Date: 16 October 2023 Correspondence Address: Fan, L.T.; Laboratory for Artificial Intelligence in Process Engineering Department of Chemical Engineering, , Kansas, 66506, United States Funding details: U.S. Environmental Protection Agency, EPA Funding details: Kansas State University, KSU Funding text 1: Although the research in this article has been funded in part by the U.S. Environmental Protection Agency under assistance agreement headquarters at Kansas State University, it has not been subjected to the and therefore may not necessarily reflect the views of the Agency and no official endorsement should be inferred. This research was partially supported by Kansas State University Center for Hazardous Substance Research. LA - English DB - MTMT ER - TY - JOUR AU - Friedler, Ferenc AU - Tarján, Klára AU - Huang, Y W AU - Fan, L T TI - Graph-Theoretic Approach to Process Synthesis: Axioms and Theorems JF - CHEMICAL ENGINEERING SCIENCE J2 - CHEM ENG SCI VL - 47 PY - 1992 SP - 1973 EP - 1988 PG - 16 SN - 0009-2509 DO - 10.1016/0009-2509(92)80315-4 UR - https://m2.mtmt.hu/api/publication/1044849 ID - 1044849 N1 - Department of Systems Engineering Research Institute of Technical Chemistry, Hungarian Academy of Sciences, P.F. 125, Veszprém, 8201, Hungary Institute of Mathematics, University of Veszprém, Veszprém, Hungary Department of Chemical Engineering, Kansas State University, Manhattan, KS 66506, United States Cited By :357 Export Date: 16 October 2023 CODEN: CESCA Correspondence Address: Friedler, F.; Department of Systems Engineering Research Institute of Technical Chemistry, Hungarian Academy of Sciences, P.F. 125, Veszprém, 8201, Hungary Funding details: U.S. Environmental Protection Agency, EPA, R-815709 Funding details: Kansas State University, KSU Funding text 1: Acknowledgments-Although the research in this article has been funded in part by the U.S. Environmental Protection Agency under assistance agreement R-815709 to the Haaar-dous Substance Research Center for U.S. EPA Regions 7 and 8 with headquarters at Kansas State University, it has not been subjected to the Agency’s peer and administrative review and therefore may not necessarily reflect the views of the Agency and no official endorsement should be inferred. This research was partially supported by Kansas State University Center for Hazardous Substance Research. LA - English DB - MTMT ER -