@article{MTMT:2418290, title = {Determination of the thermodynamically dominant metabolic pathways}, url = {https://m2.mtmt.hu/api/publication/2418290}, author = {Yun, C and Kim, TY and Zhang, T and Kim, Y and Lee, SY and Park, S and Friedler, Ferenc and Bertók, Botond}, doi = {10.1021/ie300652h}, journal-iso = {IND ENG CHEM RES}, journal = {INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH}, volume = {52}, unique-id = {2418290}, issn = {0888-5885}, abstract = {An effective strategy comprising two phases is proposed to determine the thermodynamically dominant pathways in a metabolic network of a given phenotype, involving several metabolic reactions. In the first phase, stoichiometrically feasible metabolic pathways are exhaustively identified through the flux balance analysis and the graph-theoretic method based on P-graphs. In the second phase, thermodynamically dominant pathways are selected from these stoichiometrically feasible metabolic pathways on the basis of the Gibbs free energy change of reaction. The proposed strategy's efficacy is demonstrated by applying it to two E. coli models: one is for maximal acetate and ethanol production, and the other is for maximalpoly(3-hydroxybutyrate) production. © 2012 American Chemical Society.}, keywords = {metabolism; Escherichia coli; second phase; Graph theory; E. coli; Metabolic pathways; Graph-theoretic methods; P-graphs; Dominant pathways; Flux balance analysis; metabolic network; Metabolic reactions; Gibbs free energy changes; Ethanol production; 3-Hydroxybutyrate}, year = {2013}, eissn = {1520-5045}, pages = {222-229}, orcid-numbers = {Bertók, Botond/0000-0002-1297-9792} } @article{MTMT:1892675, title = {Exhaustive identification of feasible pathways of the reaction catalyzed by a catalyst with multiactive sites via a highly effective graph-theoretic algorithm: Application to ethylene hydrogenation}, url = {https://m2.mtmt.hu/api/publication/1892675}, author = {Fan, L T and Lin, Y -C and Shafie, S and Bertók, Botond and Friedler, Ferenc}, doi = {10.1021/ie200718w}, journal-iso = {IND ENG CHEM RES}, journal = {INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH}, volume = {51}, unique-id = {1892675}, issn = {0888-5885}, abstract = {Hitherto, no attempt has been made to identify exhaustively feasible pathways for any mechanism of a given reaction catalyzed by a catalyst with multiactive sites. Two stoichiometically exact and definitely feasible mechanisms have been proposed to date for the hydrogenation of ethylene to ethane on biactive-site or triactive-site platinum catalysts. One comprises seven elementary reactions, and the other comprises eight elementary reactions; nevertheless, both mechanisms involve competitive as well as noncompetitive adsorption. Any of these mechanisms gives rise to a multitude of feasible catalytic pathways. The present work exhaustively identifies such feasible pathways by resorting to the inordinately efficient graph-theoretic algorithm based on P- graphs (process graphs). The efficacy of this algorithm has been amply demonstrated by successfully deploying it for several catalysts with single-active sites, but has never been deployed for catalysts with multiactive sites as in the current work. The availability of exhaustively identified feasible pathways for both mechanisms renders it possible to stipulate that the hydrogenation of chemisorbed chemisorbed C 2H 5 is the rate-controlling step: This step is contained in either mechanism. © 2012 American Chemical Society.}, year = {2012}, eissn = {1520-5045}, pages = {2548-2552}, orcid-numbers = {Bertók, Botond/0000-0002-1297-9792} } @article{MTMT:2060145, title = {Planning Evacuation Routes with the P-graph Framework}, url = {https://m2.mtmt.hu/api/publication/2060145}, author = {Garcia Ojeda, Juan Carlos and Bertók, Botond and Friedler, Ferenc}, doi = {10.3303/CET1229256}, journal-iso = {CHEM ENG TR}, journal = {CHEMICAL ENGINEERING TRANSACTIONS}, volume = {29}, unique-id = {2060145}, issn = {1974-9791}, year = {2012}, eissn = {2283-9216}, pages = {1531-1536}, orcid-numbers = {Bertók, Botond/0000-0002-1297-9792} } @article{MTMT:2060125, title = {Extending Process-Network Synthesis Algorithms with Time Bounds for Supply Network Design}, url = {https://m2.mtmt.hu/api/publication/2060125}, author = {Kalauz, Károly and Süle, Zoltán and Bertók, Botond and Friedler, Ferenc and Fan, L T}, doi = {10.3303/CET1229044}, journal-iso = {CHEM ENG TR}, journal = {CHEMICAL ENGINEERING TRANSACTIONS}, volume = {29}, unique-id = {2060125}, issn = {1974-9791}, year = {2012}, eissn = {2283-9216}, pages = {259-264}, orcid-numbers = {Kalauz, Károly/0009-0007-5888-5541; Bertók, Botond/0000-0002-1297-9792} } @article{MTMT:34197830, title = {Optimization software for solving vehicle assignment problems to minimize cost and environmental impact of transportation}, url = {https://m2.mtmt.hu/api/publication/34197830}, isbn = {9788895608051}, author = {Barany, M. and Bertók, Botond and Kovács, Zoltán and Friedler, Ferenc and Fan, L.T.}, doi = {10.3303/CET1021084}, journal-iso = {CHEM ENG TR}, journal = {CHEMICAL ENGINEERING TRANSACTIONS}, volume = {21}, unique-id = {34197830}, issn = {1974-9791}, abstract = {A method and software are proposed for optimal assignment of vehicles to transportation tasks in terms of total cost and emission. Each task is given by a set of attributes to be taken into account in the assignment; and this is also the case for each vehicle. The overall mileage is calculated as the sum of the lengths of all the routes to be travelled during, before, after, and between the tasks (Deaulniers et al., 1998; Baita et al., 2000). Cost and emission are assigned to the mileages of each vehicle type. Copyright © 2010 AIDIC Servizi S.r.l.}, keywords = {vehicles; Energy conservation; Costs; Environmental impact; Combinatorial optimization; Optimization software; Optimal Assignment; Vehicle types; Vehicle assignment problem}, year = {2010}, eissn = {2283-9216}, pages = {499-504}, orcid-numbers = {Bertók, Botond/0000-0002-1297-9792} } @book{MTMT:1691867, title = {Sustainability in the Process Industry. Integration and Optimization}, url = {https://m2.mtmt.hu/api/publication/1691867}, isbn = {9780071605540}, author = {Klemeš, Jiri Jaromir and Friedler, Ferenc and I, Bulatov and Varbanov, Petar}, publisher = {McGraw-Hill Education; McGraw-Hill Book Company}, unique-id = {1691867}, year = {2010} } @book{MTMT:2295364, title = {A döntéselmélet alapjai}, url = {https://m2.mtmt.hu/api/publication/2295364}, isbn = {9639345644}, author = {Temesi, József}, publisher = {Aula Kiadó Kft.}, unique-id = {2295364}, keywords = {Döntéselmélet; Döntési módszerek; egyéni és csoportos döntéstámogatás}, year = {2002}, orcid-numbers = {Temesi, József/0000-0001-7045-5914} } @article{MTMT:1044836, title = {Separation-network synthesis: global optimum through rigorous super-structure}, url = {https://m2.mtmt.hu/api/publication/1044836}, author = {Kovács, Zoltán and Ercsey, Zsolt and Friedler, Ferenc and Fan, L T}, doi = {10.1016/S0098-1354(00)00568-8}, journal-iso = {COMPUT CHEM ENG}, journal = {COMPUTERS & CHEMICAL ENGINEERING}, volume = {24}, unique-id = {1044836}, issn = {0098-1354}, year = {2000}, eissn = {1873-4375}, pages = {1881-1900}, orcid-numbers = {Ercsey, Zsolt/0000-0002-7536-3688} } @article{MTMT:1774307, title = {Exact super-structure for the synthesis of separation-networks with multiple feed-streams and sharp separators}, url = {https://m2.mtmt.hu/api/publication/1774307}, author = {Kovács, Zoltán and Ercsey, Zsolt and Friedler, Ferenc and Fan, LT}, doi = {10.1016/S0098-1354(99)80238-5}, journal-iso = {COMPUT CHEM ENG}, journal = {COMPUTERS & CHEMICAL ENGINEERING}, volume = {23}, unique-id = {1774307}, issn = {0098-1354}, year = {1999}, eissn = {1873-4375}, pages = {S1007-S1010}, orcid-numbers = {Ercsey, Zsolt/0000-0002-7536-3688} } @article{MTMT:1044848, title = {Combinatorial Algorithms for Process Synthesis}, url = {https://m2.mtmt.hu/api/publication/1044848}, author = {Friedler, Ferenc and Tarján, Klára and Huang, Y W and Fan, L T}, doi = {10.1016/S0098-1354(09)80037-9}, journal-iso = {COMPUT CHEM ENG}, journal = {COMPUTERS & CHEMICAL ENGINEERING}, volume = {16}, unique-id = {1044848}, issn = {0098-1354}, year = {1992}, eissn = {1873-4375}, pages = {S313-S320} } @article{MTMT:1044849, title = {Graph-Theoretic Approach to Process Synthesis: Axioms and Theorems}, url = {https://m2.mtmt.hu/api/publication/1044849}, author = {Friedler, Ferenc and Tarján, Klára and Huang, Y W and Fan, L T}, doi = {10.1016/0009-2509(92)80315-4}, journal-iso = {CHEM ENG SCI}, journal = {CHEMICAL ENGINEERING SCIENCE}, volume = {47}, unique-id = {1044849}, issn = {0009-2509}, year = {1992}, eissn = {1873-4405}, pages = {1973-1988} }