@article{MTMT:3038970, title = {Continuous-flow high pressure hydrogenation reactor for optimization and high-throughput synthesis}, url = {https://m2.mtmt.hu/api/publication/3038970}, author = {Jones, Richard and Godorhazy, L and Varga, N and Szalay, D and Urge, L and Darvas, Ferenc}, doi = {10.1021/cc050107o}, journal-iso = {J COMB CHEM}, journal = {JOURNAL OF COMBINATORIAL CHEMISTRY}, volume = {8}, unique-id = {3038970}, issn = {1520-4766}, abstract = {This paper reports on a novel continuous-flow hydrogenation reactor and its integration with a liquid handler to generate a fully automated high-throughput hydrogenation system for library synthesis. The reactor, named the H-Cube, combines endogenous hydrogen generation from the electrolysis of water with a continuous flow-through system. The system makes significant advances over current batch hydrogenation reactors in terms of safety, reaction validation efficiency, and rates of reaction. The hydrogenation process is described along with a detailed description of the device's main parts. The reduction of a series of functional groups, varying in difficulty up to 70 °C and 70 bar are also described. The paper concludes with the integration of the device into an automated liquid handler followed by the reduction of a nitro compound in a high throughput manner. The system is fully automated and can conduct 5 reactions in the time it takes to perform and workup one reaction manually on a standard batch reactor. © 2006 American Chemical Society.}, keywords = {PRESSURE; HEAT; ARTICLE; methodology; CATALYSIS; HYDROGENATION; molecular structure; chemical structure; instrumentation; combinatorial chemistry; Equipment Design; Combinatorial Chemistry Techniques}, year = {2006}, eissn = {1520-4774}, pages = {110-116} } @article{MTMT:35593774, title = {Catalytic transfer hydrogenation of sugar derivatives}, url = {https://m2.mtmt.hu/api/publication/35593774}, author = {Jicsinszky, L and Iványi, Róbert}, doi = {10.1016/S0144-8617(00)00319-2}, journal-iso = {CARBOHYD POLYM}, journal = {CARBOHYDRATE POLYMERS}, volume = {45}, unique-id = {35593774}, issn = {0144-8617}, year = {2001}, eissn = {1879-1344}, pages = {139-145} } @article{MTMT:35605402, title = {Introduction and General Overview of Cyclodextrin Chemistry}, url = {https://m2.mtmt.hu/api/publication/35605402}, author = {Szejtli, József}, doi = {10.1021/cr970022c}, journal-iso = {CHEM REV}, journal = {CHEMICAL REVIEWS}, volume = {98}, unique-id = {35605402}, issn = {0009-2665}, year = {1998}, eissn = {1520-6890}, pages = {1743-1754} }