@article{MTMT:32687570, title = {Gut Microbiome in Patients with Obstructive Sleep Apnoea}, url = {https://m2.mtmt.hu/api/publication/32687570}, author = {Bikov, András and Szabó, Helga and Piroska, Márton and Kunos, László and Szily, Marcell and Ligeti, Balázs and Makra, Nóra and Szabó, Dóra and Tárnoki, Dávid László and Tárnoki, Ádám Domonkos}, doi = {10.3390/app12042007}, journal-iso = {APPL SCI-BASEL}, journal = {APPLIED SCIENCES-BASEL}, volume = {12}, unique-id = {32687570}, year = {2022}, eissn = {2076-3417}, orcid-numbers = {Bikov, András/0000-0002-8983-740X; Piroska, Márton/0000-0002-6000-5044; Szily, Marcell/0000-0003-3298-9231; Szabó, Dóra/0000-0002-8601-3923; Tárnoki, Dávid László/0000-0002-7001-7647; Tárnoki, Ádám Domonkos/0000-0001-5909-3780} } @article{MTMT:31974190, title = {Association between Gut Microbial Diversity and Carotid Intima-Media Thickness}, url = {https://m2.mtmt.hu/api/publication/31974190}, author = {Szabó, Helga and Hernyes, Anita and Piroska, Márton and Ligeti, Balázs and Fussy, Peter and Zöldi, Luca and Galyasz, Szonja and Makra, Nóra and Szabó, Dóra and Tárnoki, Ádám Domonkos and Tárnoki, Dávid László}, doi = {10.3390/medicina57030195}, journal-iso = {MED LITH}, journal = {MEDICINA-LITHUANIA}, volume = {57}, unique-id = {31974190}, issn = {1010-660X}, year = {2021}, eissn = {1648-9144}, orcid-numbers = {Hernyes, Anita/0000-0001-5875-4006; Piroska, Márton/0000-0002-6000-5044; Zöldi, Luca/0000-0003-4187-1673; Szabó, Dóra/0000-0002-8601-3923; Tárnoki, Ádám Domonkos/0000-0001-5909-3780; Tárnoki, Dávid László/0000-0002-7001-7647} } @article{MTMT:31374214, title = {Bladder cancer-related microbiota. examining differences in urine and tissue samples}, url = {https://m2.mtmt.hu/api/publication/31374214}, author = {Mansour, Bassel and Monyók, Ádám and Makra, Nóra and Gajdács, Márió and Vadnay, István and Ligeti, Balázs and Juhász, János and Szabó, Dóra and Ostorházi, Eszter}, doi = {10.1038/s41598-020-67443-2}, journal-iso = {SCI REP}, journal = {SCIENTIFIC REPORTS}, volume = {10}, unique-id = {31374214}, year = {2020}, eissn = {2045-2322}, orcid-numbers = {Gajdács, Márió/0000-0003-1270-0365; Szabó, Dóra/0000-0002-8601-3923; Ostorházi, Eszter/0000-0002-9459-7316} } @article{MTMT:30724108, title = {Genetic influences on the onset of obstructive sleep apnoea and daytime sleepiness. a twin study}, url = {https://m2.mtmt.hu/api/publication/30724108}, author = {Szily, Marcell and Tárnoki, Ádám Domonkos and Tárnoki, Dávid László and Kovacs, Daniel T and Forgó, Bianka and Lee, Jooyeon and Kim, Eunae and Sung, Joohon and Kunos, László and Mészáros, Martina and Müller, Veronika and Bikov, András}, doi = {10.1186/s12931-019-1095-x}, journal-iso = {RESP RES}, journal = {RESPIRATORY RESEARCH}, volume = {20}, unique-id = {30724108}, issn = {1465-9921}, abstract = {Obstructive sleep apnoea (OSA) is one of the major sources of the excessive daily sleepiness, cognitive dysfunction, and it increases cardiovascular morbidity and mortality. Previous studies suggested a possible genetic influence, based on questionnaires but no objective genetic study was conducted to understand the exact variance underpinned by genetic factors.Seventy-one Hungarian twin pairs involved from the Hungarian Twin Registry (48 monozygotic, MZ and 23 dizygotic, DZ pairs, mean age 51 ± 15 years) underwent overnight polysomnography (Somnoscreen Plus Tele PSG, Somnomedics GMBH, Germany). Apnoea hypopnea index (AHI), respiratory disturbance index (RDI) and oxygen desaturation index (ODI) were registered. Daytime sleepiness was measured with the Epworth Sleepiness Scale (ESS). Bivariate heritability analysis was applied.The prevalence of OSA was 41% in our study population. The heritability of the AHI, ODI and RDI ranged between 69% and 83%, while the OSA, defined by an AHI ≥5/h, was itself 73% heritable. The unshared environmental component explained the rest of the variance between 17% and 31%. Daytime sleepiness was mostly determined by the environment, and the variance was influenced in 34% by the additive genetic factors. These associations were present after additional adjustment for body mass index.OSA and the indices of OSA severity are heritable, while daytime sleepiness is mostly influenced by environmental factors. Further studies should elucidate whether close relatives of patients with OSA may benefit from early family risk based screening.}, keywords = {Environment; heritability; Sleepiness; sleep apnoea}, year = {2019}, eissn = {1465-993X}, orcid-numbers = {Szily, Marcell/0000-0003-3298-9231; Tárnoki, Ádám Domonkos/0000-0001-5909-3780; Tárnoki, Dávid László/0000-0002-7001-7647; Mészáros, Martina/0000-0003-1065-3577; Müller, Veronika/0000-0002-1398-3187; Bikov, András/0000-0002-8983-740X} } @article{MTMT:31122140, title = {The Hungarian Twin Registry Update: Turning From a Voluntary to a Population-Based Registry}, url = {https://m2.mtmt.hu/api/publication/31122140}, author = {Tárnoki, Ádám Domonkos and Tárnoki, Dávid László and Forgó, Bianka and Szabó, Helga and Melicher, Dóra and Metneki, Julia and Littvay, Levente}, doi = {10.1017/thg.2019.100}, journal-iso = {TWIN RES HUM GENET}, journal = {TWIN RESEARCH AND HUMAN GENETICS}, volume = {22}, unique-id = {31122140}, issn = {1832-4274}, year = {2019}, eissn = {1839-2628}, pages = {561-566}, orcid-numbers = {Tárnoki, Ádám Domonkos/0000-0001-5909-3780; Tárnoki, Dávid László/0000-0002-7001-7647; Melicher, Dóra/0000-0003-4848-1424; Littvay, Levente/0000-0003-2022-6886} } @article{MTMT:2101783, title = {The Hungarian Twin Registry}, url = {https://m2.mtmt.hu/api/publication/2101783}, author = {Littvay, Levente and Metneki, J and Tárnoki, Ádám Domonkos and Tárnoki, Dávid László}, doi = {10.1017/thg.2012.76}, journal-iso = {TWIN RES HUM GENET}, journal = {TWIN RESEARCH AND HUMAN GENETICS}, volume = {16}, unique-id = {2101783}, issn = {1832-4274}, abstract = {The first Hungarian Twin Registry was established in Budapest in 1970 through the mandatory reporting of multiple-births. In the 1980s a second, volunteer adult registry was also founded. Unfortunately, both registries ceased to exist in the 1990s. Efforts started in 2006 to revive a Hungarian twin registry. The team spearheading this effort reports here on this progress. Currently, the voluntary Hungarian Twin Registry consists of 310 adult twin pairs and multiplets. Current research focuses on cardiovascular and respiratory health and yielded multiple awards and publications. Efforts are on the way to expand into social, psychological, and obesity studies.}, year = {2013}, eissn = {1839-2628}, pages = {185-189}, orcid-numbers = {Littvay, Levente/0000-0003-2022-6886; Tárnoki, Ádám Domonkos/0000-0001-5909-3780; Tárnoki, Dávid László/0000-0002-7001-7647} }