TY  - JOUR
AU  - Márkus, Róbert
AU  - Lerner, Zita
AU  - Honti, Viktor
AU  - Csordás, Gábor
AU  - Zsámboki, János
AU  - Cinege, Gyöngyi Ilona
AU  - Párducz, Árpád
AU  - Lukacsovich, Tamás
AU  - Kurucz, Judit Éva
AU  - Andó, István
TI  - Multinucleated Giant Hemocytes Are Effector Cells in Cell-Mediated Immune Responses of Drosophila
JF  - JOURNAL OF INNATE IMMUNITY
J2  - J INNATE IMMUN
VL  - 7
PY  - 2015
IS  - 4
SP  - 340
EP  - 353
PG  - 14
SN  - 1662-811X
DO  - 10.1159/000369618
UR  - https://m2.mtmt.hu/api/publication/2853634
ID  - 2853634
N1  - Megjegyzés-25258522
Hiányzó Jelleg: 'JOUR\n\nArticle'
Admin megjegyzés-25258522
tblcategory: (Category) ('JOUR\n\nArticle') #Jelleg
AB  - We identified and characterized a so far unrecognized cell type, dubbed the multinucleated giant hemocyte (MGH), in the ananassae subgroup of Drosophilidae. Here, we describe the functional and ultrastructural characteristics of this novel blood cell type as well as its characterization with a set of discriminative immunological markers. MGHs are encapsulating cells that isolate and kill the parasite without melanization. They share some properties with but differ considerably from lamellocytes, the encapsulating cells of Drosophila melanogaster, the broadly used model organism in studies of innate immunity. MGHs are nonproliferative effector cells that are derived from phagocytic cells of the sessile tissue and the circulation, but do not exhibit phagocytic activity. In contrast to lamellocytes, MGHs are gigantic cells with filamentous projections and contain many nuclei, which are the result of the fusion of several cells. Although the structure of lamellocytes and MGHs differ remarkably, their function in the elimination of parasites is similar, which is potentially the result of the convergent evolution of interactions between hosts and parasites in different geographic regions. MGHs are highly motile and share several features with mammalian multinucleated giant cells, a syncytium of macrophages formed during granulomatous inflammation. © 2015 S. Karger AG, Basel
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Márkus, Róbert
AU  - Laurinyecz, Barbara
AU  - Kurucz, Judit Éva
AU  - Honti, Viktor
AU  - Bajusz, Izabella
AU  - Sipos, Botond
AU  - Somogyi, Kálmán
AU  - Kronhamn, J
AU  - Hultmark, D
AU  - Andó, István
TI  - Sessile hemocytes as a hematopoietic compartment in drosophila melanogaster
JF  - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
J2  - P NATL ACAD SCI USA
VL  - 106
PY  - 2009
IS  - 12
SP  - 4805
EP  - 4809
PG  - 5
SN  - 0027-8424
DO  - 10.1073/pnas.0801766106
UR  - https://m2.mtmt.hu/api/publication/1920757
ID  - 1920757
N1  - Cited By :174            
            Export Date: 30 June 2022            
            CODEN: PNASA
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Kurucz, Judit Éva
AU  - Váczi, Balázs
AU  - Márkus, Róbert
AU  - Laurinyecz, Barbara
AU  - Vilmos, Péter
AU  - Zsámboki, János
AU  - Csorba, Kinga
AU  - Gateff, E
AU  - Hultmark, D
AU  - Andó, István
TI  - Definition of Drosophila hemocyte subsets by cell-type specific antigens
JF  - ACTA BIOLOGICA HUNGARICA (1983-2018)
J2  - ACTA BIOL HUNG
VL  - 58
PY  - 2007
IS  - Suppl. 1
SP  - 95
EP  - 111
PG  - 17
SN  - 0236-5383
DO  - 10.1556/ABiol.58.2007.Suppl.8
UR  - https://m2.mtmt.hu/api/publication/1915261
ID  - 1915261
AB  - We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. Oil the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmalocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged ill four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocyles.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Kurucz, Judit Éva
AU  - Márkus, Róbert
AU  - Zsámboki, János
AU  - Medzihradszky F., Katalin
AU  - Darula, Zsuzsanna
AU  - Vilmos, Péter
AU  - Udvardy, Andor
AU  - Krausz, Ildikó
AU  - Lukacsovich, Tamás
AU  - Gateff, E
AU  - Zettervall, CJ
AU  - Hultmark, D
AU  - Andó, István
TI  - Nimrod, a Putative Phagocytosis Receptor With Egf Repeats in Drosophila Plasmatocytes
JF  - CURRENT BIOLOGY
J2  - CURR BIOL
VL  - 17
PY  - 2007
IS  - 7
SP  - 649
EP  - 654
PG  - 6
SN  - 0960-9822
DO  - 10.1016/j.cub.2007.02.041
UR  - https://m2.mtmt.hu/api/publication/1915010
ID  - 1915010
N1  - Megjegyzés-22232309
Z9: 60 
DI: 10.1016/j.cub.2007.02.041
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Rus, Florentina
AU  - Kurucz, Judit Éva
AU  - Márkus, Róbert
AU  - Sinenko, SA
AU  - Laurinyecz, Barbara
AU  - Pataki, Andrea Csilla
AU  - Gausz, János
AU  - Hegedűs, Zoltán
AU  - Udvardy, Andor
AU  - Hultmark, D
AU  - Andó, István
TI  - Expression pattern of Filamin-240 in Drosophila blood cells
JF  - GENE EXPRESSION PATTERNS
J2  - GENE EXPR PATTERNS
VL  - 6
PY  - 2006
IS  - 8
SP  - 928
EP  - 934
PG  - 7
SN  - 1567-133X
DO  - 10.1016/j.modgep.2006.03.005
UR  - https://m2.mtmt.hu/api/publication/1786592
ID  - 1786592
N1  - Export Date: 27 January 2024; CODEN: GEPEA
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Weinstock, GM
AU  - Robinson, GE
AU  - Gibbs, RA
AU  - Worley, KC
AU  - Evans, JD
AU  - Maleszka, R
AU  - Robertson, HM
AU  - Weaver, DB
AU  - Beye, M
AU  - Bork, P
AU  - Elsik, CG
AU  - Hartfelder, K
AU  - Hunt, GJ
AU  - Zdobnov, EM
AU  - Amdam, GV
AU  - Bitondi, MMG
AU  - Collins, AM
AU  - Cristino, AS
AU  - Lattorff, HMG
AU  - Lobo, CH
AU  - Moritz, RFA
AU  - Nunes, FMF
AU  - Page, RE
AU  - Simoes, ZLP
AU  - Wheeler, D
AU  - Carninci, P
AU  - Fukuda, S
AU  - Hayashizaki, Y
AU  - Kai, C
AU  - Kawai, J
AU  - Sakazume, N
AU  - Sasaki, D
AU  - Tagami, M
AU  - Albert, S
AU  - Baggerman, G
AU  - Beggs, KT
AU  - Bloch, G
AU  - Cazzamali, G
AU  - Cohen, M
AU  - Drapeau, MD
AU  - Eisenhardt, D
AU  - Emore, C
AU  - Ewing, MA
AU  - Fahrbach, SE
AU  - Foret, S
AU  - Grimmelikhuijzen, CJP
AU  - Hauser, F
AU  - Hummon, AB
AU  - Huybrechts, J
AU  - Jones, AK
AU  - Kadowaki, T
AU  - Kaplan, N
AU  - Kucharski, R
AU  - Leboulle, G
AU  - Linial, M
AU  - Littleton, JT
AU  - Mercer, AR
AU  - Richmond, TA
AU  - Rodriguez-Zas, SL
AU  - Rubin, EB
AU  - Sattelle, DB
AU  - Schlipalius, D
AU  - Schoofs, L
AU  - Shemesh, Y
AU  - Sweedler, JV
AU  - Velarde, R
AU  - Verleyen, P
AU  - Vierstraete, E
AU  - Williamson, MR
AU  - Ament, SA
AU  - Brown, SJ
AU  - Corona, M
AU  - Dearden, PK
AU  - Dunn, WA
AU  - Elekonich, MM
AU  - Fujiyuki, T
AU  - Gattermeier, I
AU  - Gempe, T
AU  - Hasselmann, M
AU  - Kadowaki, T
AU  - Kage, E
AU  - Kamikouchi, A
AU  - Kubo, T
AU  - Kucharski, R
AU  - Kunieda, T
AU  - Lorenzen, MD
AU  - Milshina, NV
AU  - Morioka, M
AU  - Ohashi, K
AU  - Overbeek, R
AU  - Ross, CA
AU  - Schioett, M
AU  - Shippy, T
AU  - Takeuchi, H
AU  - Toth, AL
AU  - Willis, JH
AU  - Wilson, MJ
AU  - Gordon, KHJ
AU  - Letunic, I
AU  - Hackett, K
AU  - Peterson, J
AU  - Felsenfeld, A
AU  - Guyer, M
AU  - Solignac, M
AU  - Agarwala, R
AU  - Cornuet, JM
AU  - Monnerot, M
AU  - Mougel, F
AU  - Reese, JT
AU  - Vautrin, D
AU  - Gillespie, JJ
AU  - Cannone, JJ
AU  - Gutell, RR
AU  - Johnston, JS
AU  - Eisen, MB
AU  - Iyer, VN
AU  - Iyer, V
AU  - Kosarev, P
AU  - Mackey, AJ
AU  - Solovyev, V
AU  - Souvorov, A
AU  - Aronstein, KA
AU  - Bilikova, K
AU  - Chen, YP
AU  - Clark, AG
AU  - Decanini, LI
AU  - Gelbart, WM
AU  - Hetru, C
AU  - Hultmark, D
AU  - Imler, JL
AU  - Jiang, HB
AU  - Kanost, M
AU  - Kimura, K
AU  - Lazzaro, BP
AU  - Lopez, DL
AU  - Simuth, J
AU  - Thompson, GJ
AU  - Zou, Z
AU  - De Jong, P
AU  - Sodergren, E
AU  - Csűrös, Miklós
AU  - Milosavljevic, A
AU  - Osoegawa, K
AU  - Richards, S
AU  - Shu, CL
AU  - Duret, L
AU  - Elhaik, E
AU  - Graur, D
AU  - Anzola, JM
AU  - Campbell, KS
AU  - Childs, KL
AU  - Collinge, D
AU  - Crosby, MA
AU  - Dickens, CM
AU  - Grametes, LS
AU  - Grozinger, CM
AU  - Jones, PL
AU  - Jorda, M
AU  - Ling, X
AU  - Matthews, BB
AU  - Miller, J
AU  - Mizzen, C
AU  - Peinado, MA
AU  - Reid, JG
AU  - Russo, SM
AU  - Schroeder, AJ
AU  - St, Pierre SE
AU  - Wang, Y
AU  - Zhou, PL
AU  - Jiang, HY
AU  - Kitts, P
AU  - Ruef, B
AU  - Venkatraman, A
AU  - Zhang, L
AU  - Aquino-Perez, G
AU  - Whitfield, CW
AU  - Behura, SK
AU  - Berlocher, SH
AU  - Sheppard, WS
AU  - Smith, DR
AU  - Suarez, AV
AU  - Tsutsui, ND
AU  - Wei, XH
AU  - Wheeler, D
AU  - Havlak, P
AU  - Li, BS
AU  - Liu, Y
AU  - Sodergren, E
AU  - Jolivet, A
AU  - Lee, S
AU  - Nazareth, LV
AU  - Pu, LL
AU  - Thorn, R
AU  - Stolc, V
AU  - Newman, T
AU  - Samanta, M
AU  - Tongprasit, WA
AU  - Claudianos, C
AU  - Berenbaum, MR
AU  - Biswas, S
AU  - de Graaf, DC
AU  - Feyereisen, R
AU  - Johnson, RM
AU  - Oakeshott, JG
AU  - Ranson, H
AU  - Schuler, MA
AU  - Muzny, D
AU  - Chacko, J
AU  - Davis, C
AU  - Dinh, H
AU  - Gill, R
AU  - Hernandez, J
AU  - Hines, S
AU  - Hume, J
AU  - Jackson, L
AU  - Kovar, C
AU  - Lewis, L
AU  - Miner, G
AU  - Morgan, M
AU  - Nguyen, N
AU  - Okwuonu, G
AU  - Paul, H
AU  - Santibanez, J
AU  - Savery, G
AU  - Svatek, A
AU  - Villasana, D
AU  - Wright, R
TI  - Insights into social insects from the genome of the honeybee Apis mellifera
JF  - NATURE
J2  - NATURE
VL  - 443
PY  - 2006
IS  - 7114
SP  - 931
EP  - 949
PG  - 19
SN  - 0028-0836
DO  - 10.1038/nature05260
UR  - https://m2.mtmt.hu/api/publication/1921888
ID  - 1921888
N1  - CA: Honeybee Genome Sequencing Consort 
Z9: 506
AB  - Here we report the genome sequence of the honeybee Apis mellifera, a key model for social behaviour and essential to global ecology through pollination. Compared with other sequenced insect genomes, the A. mellifera genome has high A+T and CpG contents, lacks major transposon families, evolves more slowly, and is more similar to vertebrates for circadian rhythm, RNA interference and DNA methylation genes, among others. Furthermore, A. mellifera has fewer genes for innate immunity, detoxification enzymes, cuticle-forming proteins and gustatory receptors, more genes for odorant receptors, and novel genes for nectar and pollen utilization, consistent with its ecology and social organization. Compared to Drosophila, genes in early developmental pathways differ in Apis, whereas similarities exist for functions that differ markedly, such as sex determination, brain function and behaviour. Population genetics suggests a novel African origin for the species A. mellifera and insights into whether Africanized bees spread throughout the New World via hybridization or displacement.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Williams, MJ
AU  - Andó, István
AU  - Hultmark, D
TI  - Drosophila melanogaster Rac2 is necessary for a proper cellular immune response
JF  - GENES TO CELLS
J2  - GENES CELLS
VL  - 10
PY  - 2005
SP  - 813
EP  - 823
PG  - 11
SN  - 1356-9597
DO  - 10.1111/j.1365-2443.2005.00883.x
UR  - https://m2.mtmt.hu/api/publication/1913913
ID  - 1913913
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Vilmos, Péter
AU  - Nagy, István
AU  - Kurucz, Judit Éva
AU  - Hultmark, D
AU  - Gateff, E
AU  - Andó, István
TI  - A rapid rosetting method for separation of hemocyte sub-populations of Drosophila melanogaster
JF  - DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
J2  - DEV COMP IMMUNOL
VL  - 28
PY  - 2004
IS  - 6
SP  - 555
EP  - 563
PG  - 9
SN  - 0145-305X
DO  - 10.1016/j.dci.2003.10.001
UR  - https://m2.mtmt.hu/api/publication/1951675
ID  - 1951675
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Zettervall, CJ
AU  - Anderl, I
AU  - Williams, MJ
AU  - Palmer, R
AU  - Kurucz, Judit Éva
AU  - Andó, István
AU  - Hultmark, D
TI  - A directed screen for genes involved in Drosophila blood cell activation
JF  - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
J2  - P NATL ACAD SCI USA
VL  - 101
PY  - 2004
IS  - 39
SP  - 14192
EP  - 14197
PG  - 6
SN  - 0027-8424
DO  - 10.1073/pnas.0403789101
UR  - https://m2.mtmt.hu/api/publication/1913536
ID  - 1913536
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Kurucz, Judit Éva
AU  - Zettervall, CJ
AU  - Sinka, Rita
AU  - Vilmos, Péter
AU  - Pivarcsi, A
AU  - Ekengren, S
AU  - Hegedűs, Zoltán
AU  - Andó, István
AU  - Hultmark, D
TI  - Hemese, a hemocyte-specific transmembrane protein, affects the cellular immune response in Drosophila
JF  - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
J2  - P NATL ACAD SCI USA
VL  - 100
PY  - 2003
IS  - 5
SP  - 2622
EP  - 2627
PG  - 6
SN  - 0027-8424
DO  - 10.1073/pnas.0436940100
UR  - https://m2.mtmt.hu/api/publication/1912851
ID  - 1912851
LA  - English
DB  - MTMT
ER  -