TY  - JOUR
AU  - Bókony, Veronika
AU  - Ujhegyi, Nikolett
AU  - Hamow, Kamirán Áron
AU  - Bosch, Jaime
AU  - Thumsová, Barbora
AU  - Vörös, Judit
AU  - Aspbury, Andrea S.
AU  - Gabor, Caitlin R.
TI  - Stressed tadpoles mount more efficient glucocorticoid negative feedback in anthropogenic habitats due to phenotypic plasticity
JF  - SCIENCE OF THE TOTAL ENVIRONMENT
J2  - SCI TOTAL ENVIRON
VL  - 753
PY  - 2021
PG  - 11
SN  - 0048-9697
DO  - 10.1016/j.scitotenv.2020.141896
UR  - https://m2.mtmt.hu/api/publication/31614544
ID  - 31614544
N1  - Funding Agency and Grant Number: Fulbright Research Grant; NRDI Fund of the National Research, Development and Innovation Office of Hungary ["OTKA"-115402, 2019-2.1.11-TET2019-00026];  [GINOP-2.3.3-15-2016-00018]
            Funding text: The study was supported by a Fulbright Research Grant to CRG, and by the NRDI Fund of the National Research, Development and Innovation Office of Hungary (grants "OTKA"-115402 and 2019-2.1.11-TET2019-00026 to VB). GINOP-2.3.3-15-2016-00018 supported the UPLCMS/MS analysis. None of the funding sources had any influence on the study design, collection, analysis, and interpretation of data, writing of the paper, or decision to submit it for publication.
Lendület Evolutionary Ecology Research Group, Centre for Agricultural Research, Plant Protection Institute, Herman Ottó út 15, Budapest, 1022, Hungary            
            Plant Protection Institute, Centre for Agricultural Research, Brunszvik u. 2, Martonvásár, 2462, Hungary            
            Museo Nacional de Ciencias Naturales-CSIC, José Gutiérrez Abascal 2, Madrid, 28006, Spain            
            Research Unit of Biodiversity (CSIC, UO, PA), Oviedo University - Campus Mieres, Edificio de Investigación, Gonzalo Gutiérrez Quirós s/n, Mieres, 33600, Spain            
            Department of Zoology, Hungarian Natural History Museum, Baross u. 13, 1088, Budapest, Hungary            
            Department of Biology, Texas State University, 601 University Drive, San Marcos, TX 78666, United States            
            Export Date: 1 March 2021            
            CODEN: STEVA            
            Correspondence Address: Bókony, V.; Lendület Evolutionary Ecology Research Group, Plant Protection Institute, Herman Ottó út 15, Hungary; email: bokony.veronika@atk.hu
Lendület Evolutionary Ecology Research Group, Centre for Agricultural Research, Plant Protection Institute, Herman Ottó út 15, Budapest, 1022, Hungary            
            Plant Protection Institute, Centre for Agricultural Research, Brunszvik u. 2, Martonvásár, 2462, Hungary            
            Museo Nacional de Ciencias Naturales-CSIC, José Gutiérrez Abascal 2, Madrid, 28006, Spain            
            Research Unit of Biodiversity (CSIC, UO, PA), Oviedo University - Campus Mieres, Edificio de Investigación, Gonzalo Gutiérrez Quirós s/n, Mieres, 33600, Spain            
            Department of Zoology, Hungarian Natural History Museum, Baross u. 13, 1088, Budapest, Hungary            
            Department of Biology, Texas State University, 601 University Drive, San Marcos, TX 78666, United States            
            Cited By :4            
            Export Date: 14 September 2021            
            CODEN: STEVA            
            Correspondence Address: Bókony, V.; Lendület Evolutionary Ecology Research Group, Plant Protection Institute, Herman Ottó út 15, Hungary; email: bokony.veronika@atk.hu
AB  - Coping with anthropogenic environmental change is among the greatest challenges faced by wildlife, and endocrine flexibility is a potentially crucial coping mechanism. Animals may adapt to anthropogenic environments by dampening their glucocorticoid stress response, but empirical tests of this hypothesis have provided mixed evidence. An alternative hypothesis is that a non-attenuated stress response and efficient negative feedback are favored in anthropogenic habitats. To test this idea, we non-invasively sampled corticosterone release rates of common toad (Bufo bufo) tadpoles in agricultural, urban, and natural habitats, and quantified their stress response and negative feedback by a standardized stress-and-recovery protocol. We repeated the same sampling with tadpoles raised from eggs from the same ponds in a common-garden experiment to infer if the differences observed between populations in different habitats were due to individual phenotypic plasticity rather than microevolution or transgenerational effects. We found that, compared to tadpoles in natural ponds, urban tadpoles had higher baseline and stressed corticosterone release rates, and tadpoles in agricultural ponds had similar corticosterone release rates but greater stress-induced change, indicating stronger stress responses in both types of anthropogenic habitats. As predicted, tadpoles in both agricultural and urban ponds showed more efficient negative feedback than did tadpoles in natural ponds. Water pollution levels, as indicated by the concentrations of carbamazepine and corticoid-disrupting compounds in pond water, contributed to elevating the stress response regardless of land use. Infection by neither Batrachochytrium dendrobatidis nor Ranavirus was detected in free-living tadpoles. No habitat-related glucocorticoid differences persisted in the common-garden experiment. These results suggest that toad tadpoles in anthropogenic habitats increased their glucocorticoid flexibility via phenotypic plasticity. The coupling of stronger stress response and stronger negative feedback in these habitats supports the importance of rapidly "turning on and off" the stress response as a mechanism for coping with anthropogenic environmental change. (C) 2020 The Authors. Published by Elsevier B.V.
LA  - English
DB  - MTMT
ER  -