TY - JOUR AU - Péterfi, Zalán AU - Geiszt, Miklós TI - Peroxidasins: novel players in tissue genesis JF - TRENDS IN BIOCHEMICAL SCIENCES J2 - TRENDS BIOCHEM SCI VL - 39 PY - 2014 IS - 7 SP - 305 EP - 307 PG - 3 SN - 0968-0004 DO - 10.1016/j.tibs.2014.05.005 UR - https://m2.mtmt.hu/api/publication/2706633 ID - 2706633 AB - Stabilization of extracellular matrix by protein crosslinking is a universal and essential process in multicellular organisms. Recent findings revealed that peroxidasin, a unique heme-peroxidase, produces hypohalides to support matrix synthesis. Unexpectedly, the highly reactive and potentially damaging hypohalides mediate the formation of sulfilimine bonds between adjacent collagen IV protomers. This crosslink is a fundamental feature of basal membranes, defining peroxidasin-dependent oxidant generation and sulfilimine crosslink formation as an elemental mechanism of tissue biogenesis. © 2014 Elsevier Ltd. All rights reserved. LA - English DB - MTMT ER - TY - JOUR AU - Lahnsteiner, F AU - Urbányi, Béla AU - Horváth, Ákos AU - Weismann, T TI - Bio-markers for egg quality determination in cyprinid fish JF - AQUACULTURE J2 - AQUACULTURE VL - 195 PY - 2001 IS - 3-4 SP - 331 EP - 352 PG - 22 SN - 0044-8486 DO - 10.1016/S0044-8486(00)00550-0 UR - https://m2.mtmt.hu/api/publication/1134200 ID - 1134200 LA - English DB - MTMT ER -