@article{MTMT:3338708,
	title = {Diabeteses kisér-károsodás vizsgálata optikai koherencia tomográfián alapuló angiográfiával},
	url = {https://m2.mtmt.hu/api/publication/3338708},
	author = {Czakó, Cecilia Nóra and Sándor, Gábor László and Ecsedy, Mónika and Szepessy, Zsuzsanna and Borbándy, Ágnes and Resch, Miklós and Papp, András and Récsán, Zsuzsanna and Horváth, Hajnalka and Nagy, Zoltán Zsolt and Kovács, Illés},
	doi = {10.1556/650.2018.30962},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {159},
	unique-id = {3338708},
	issn = {0030-6002},
	abstract = {INTRODUCTION: Optical coherence tomography angiography is a non-invasive imaging technique that is able to visualize the different retinal vascular layers using motion contrast to detect blood flow without intravenous dye injection. This method might help to assess microangiopathy in diabetic retinopathy during screening and follow-up. AIM: To quantify retinal microvasculature alterations in both eyes of diabetic patients in relation to systemic risk factors using optical coherence tomography angiography. METHOD: Both eyes of 36 diabetic patients and 45 individuals without diabetes were examined. Duration of diabetes, insulin therapy, blood pressure, HbA1c, dyslipidemia, axial length and the presence of diabetic retinopathy were recorded. Retinal vessel density was measured by optical coherence tomography angiography. The effect of risk factors on vessel density and between-eye asymmetry was assessed using multivariable regression analysis. RESULTS: Vessel density was significantly lower and between-eye difference was significantly higher in diabetic patients compared to controls (p<0.05). Both vessel density and between-eye asymmetry significantly correlated with diabetes duration (p<0.05) after controlling for the effect of risk factors. The between-eye asymmetry in vessel density was significantly higher in patients without clinically detectable diabetic retinopathy compared to control subjects (p<0.001). CONCLUSIONS: There is a decrease in retinal vessel density and an increase in between-eye asymmetry in patients with diabetes compared to healthy subjects. By using optical coherence tomography angiography, the detection of these microvascular alterations is possible before clinically detectable diabetic retinopathy and might serve as a useful tool in both screening and timing of treatment. Orv Hetil. 2018; 159(8): 320-326.},
	keywords = {diabetic retinopathy; optical coherence tomography angiography},
	year = {2018},
	eissn = {1788-6120},
	pages = {320-326},
	orcid-numbers = {Czakó, Cecilia Nóra/0000-0001-9424-7853; Sándor, Gábor László/0000-0002-2484-9848; Ecsedy, Mónika/0000-0001-8472-2382; Szepessy, Zsuzsanna/0000-0002-0558-1276; Resch, Miklós/0000-0002-8285-1153; Papp, András/0000-0002-6824-2909; Récsán, Zsuzsanna/0000-0003-3456-6662; Nagy, Zoltán Zsolt/0000-0002-7330-0464; Kovács, Illés/0000-0001-5763-0482}
}

@article{MTMT:3408164,
	title = {Choroidal thickness changes in non-treated eyes of patients with diabetes: swept-source optical coherence tomography study},
	url = {https://m2.mtmt.hu/api/publication/3408164},
	author = {Horváth, Hajnalka and Kovács, Illés and Sándor, Gábor László and Czakó, Cecilia Nóra and Mallar, K and Récsán, Zsuzsanna and Somogyi, Anikó and Nagy, Zoltán Zsolt and Ecsedy, Mónika},
	doi = {10.1007/s00592-018-1169-0},
	journal-iso = {ACTA DIABETOL},
	journal = {ACTA DIABETOLOGICA},
	volume = {55},
	unique-id = {3408164},
	issn = {0940-5429},
	abstract = {To measure choroidal thickness (CT) in diabetic eyes and its correlation with metabolic status and the severity of diabetic retinopathy (DR). Prospective cross-sectional study using swept-source optical coherence tomography. CT maps of 96 treatment na < ve eyes of 48 patients with diabetes were compared to 46 eyes of 23 healthy controls. CT changes and their relation to diabetes, age, gender, disease duration, hypertension (HT), hemoglobin A1c level, type and severity of DR were evaluated. A significantly thinner choroid was measured in patients with diabetes compared to controls (p < 0.009). In the diabetic group age, gender, disease duration and HT were significantly correlated with CT in univariable regression models (p < 0.05). In multivariable analysis, the duration of diabetes significantly negatively correlated with CT (p = 0.02). According to analysis of variance, there was a significant difference among means of CT in different stages of DR (p = 0.002), with thinner CT in cases with more advanced DR. In a multivariable predictive model, thinner CT was associated with an increased risk for the presence of DR (p = 0.02). Diabetes mellitus itself and the severity of DR affect CT significantly, even after adjusting for the effects of confounding systemic factors. Disease duration seems to be associated with a reduction of choroidal thickness. Decreased CT proved to be correlated with the severity of DR.},
	keywords = {RISK-FACTORS; Angiography; diabetic retinopathy; retinopathy; Macular Edema; retinal thickness; Choroidal thickness; HEALTHY EYES; CHOROIDOPATHY; SOURCE OCT; SPECTRAL-DOMAIN; Swept-source optical coherence tomography; Diabetic choroidopathy},
	year = {2018},
	eissn = {1432-5233},
	pages = {927-934},
	orcid-numbers = {Kovács, Illés/0000-0001-5763-0482; Sándor, Gábor László/0000-0002-2484-9848; Czakó, Cecilia Nóra/0000-0001-9424-7853; Récsán, Zsuzsanna/0000-0003-3456-6662; Somogyi, Anikó/0000-0003-0807-260X; Nagy, Zoltán Zsolt/0000-0002-7330-0464; Ecsedy, Mónika/0000-0001-8472-2382}
}

@article{MTMT:3131983,
	title = {Diabetes and diabetic retinopathy in people aged 50 years and older in Hungary},
	url = {https://m2.mtmt.hu/api/publication/3131983},
	author = {Tóth, Gábor and Szabó, Dorottya and Sándor, Gábor László and Szalai, Irén and Lukacs, R and Pék, Anita and Tóth, Georgina and Papp, András and Nagy, Zoltán Zsolt and Limburg, H and Németh, János Tibor},
	doi = {10.1136/bjophthalmol-2016-309016},
	journal-iso = {BRIT J OPHTHALMOL},
	journal = {BRITISH JOURNAL OF OPHTHALMOLOGY},
	volume = {101},
	unique-id = {3131983},
	issn = {0007-1161},
	abstract = {BACKGROUND/AIMS: The purpose of this study was to estimate the prevalence of diabetes mellitus (DM) and diabetic retinopathy (DR) in the population aged 50 years and older in Hungary, and to assess the coverage of diabetic eye care services. METHODS: In total, 105 clusters of 35 people aged 50 years or older were randomly selected. The standardised rapid assessment of avoidable blindness (RAAB) with the diabetic retinopathy module (DRM) was used. Participants were classified as having DM if they were known to have DM or if their random blood glucose level was >/=200 mg/dL. Dilated fundus examination and Scottish DR grading were performed. RESULTS: In total, 3523 (95.9%) out of 3675 eligible subjects were examined. And 705 (20.0%) out of 3523 had known (661) or newly diagnosed DM (44). Twenty per cent of participants with known DM had a blood glucose level >/=200 mg/dL, and 27.4% had never had an ophthalmological examination for DR. Prevalence of DR and/or maculopathy was 20.7% and prevalence of sight-threatening DR (STDR) was 4.3% in one or both eyes among participants with DM. CONCLUSIONS: Prevalence of DM was in line with findings of other RAAB+DRM surveys and slightly lower than the unpublished earlier age-matched Hungarian estimate. Prevalence of DR was slightly lower than expected. The prevalence of STDR was low in people aged 50 years and older in Hungary compared with the results of other RAAB with DRM surveys. DR screening coverage was low. To prevent severe complications of DM and possible concomitant visual loss, the coverage of ophthalmic examinations in patients with DM should be increased.},
	year = {2017},
	eissn = {1468-2079},
	pages = {965-969},
	orcid-numbers = {Tóth, Gábor/0000-0002-9176-9442; Sándor, Gábor László/0000-0002-2484-9848; Szalai, Irén/0000-0001-9245-4285; Papp, András/0000-0002-6824-2909; Nagy, Zoltán Zsolt/0000-0002-7330-0464; Németh, János Tibor/0000-0001-8575-4888}
}