@article{MTMT:30807220,
	title = {Unravelling the Role of Trophoblastic-Derived Extracellular Vesicles in Regulatory T Cell Differentiation},
	url = {https://m2.mtmt.hu/api/publication/30807220},
	author = {Kovács, Árpád Ferenc and Fekete, Nóra and Turiák, Lilla and Ács, András and Kőhidai, László and Buzás, Edit Irén and Pállinger, Éva},
	doi = {10.3390/ijms20143457},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {20},
	unique-id = {30807220},
	issn = {1661-6596},
	keywords = {miRNA; Regulatory T cells; Extracellular vesicles; EVs; C19MC; HSPE1},
	year = {2019},
	eissn = {1422-0067},
	orcid-numbers = {Kovács, Árpád Ferenc/0000-0002-7742-160X; Kőhidai, László/0000-0002-9002-0296; Buzás, Edit Irén/0000-0002-3744-206X; Pállinger, Éva/0000-0002-5789-0951}
}

@article{MTMT:3366649,
	title = {The impact of circulating preeclampsia-associated extracellular vesicles on the migratory activity and phenotype of THP-1 monocytic cells},
	url = {https://m2.mtmt.hu/api/publication/3366649},
	author = {Kovács, Árpád Ferenc and Láng, Orsolya and Turiák, Lilla and Ács, András and Kőhidai, László and Fekete, Nóra and Alasztics, Bálint and Mészáros, Tamás and Buzás, Edit Irén and Rigó, János and Pállinger, Éva},
	doi = {10.1038/s41598-018-23706-7},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {8},
	unique-id = {3366649},
	issn = {2045-2322},
	year = {2018},
	eissn = {2045-2322},
	orcid-numbers = {Kovács, Árpád Ferenc/0000-0002-7742-160X; Láng, Orsolya/0000-0002-2787-2154; Kőhidai, László/0000-0002-9002-0296; Alasztics, Bálint/0000-0002-4011-8439; Buzás, Edit Irén/0000-0002-3744-206X; Rigó, János/0000-0003-2762-6516; Pállinger, Éva/0000-0002-5789-0951}
}

@article{MTMT:3273020,
	title = {Various levels of circulating exosomal total-miRNA and miR-210 hypoxamiR in different forms of pregnancy hypertension},
	url = {https://m2.mtmt.hu/api/publication/3273020},
	author = {Biró, Orsolya and Alasztics, Bálint and Molvarec, Attila and Joó, József Gábor and Nagy, Bálint and Rigó, János},
	doi = {10.1016/j.preghy.2017.09.002},
	journal-iso = {PREGNANCY HYPERTENS},
	journal = {PREGNANCY HYPERTENSION},
	volume = {10},
	unique-id = {3273020},
	issn = {2210-7789},
	abstract = {Introduction: Hypertension is a common complication during pregnancy, affecting 10% of pregnant women worldwide. Several microRNA (miRNA) were shown to be involved in hypertensive disorders of pregnancy. In preeclampsia (PE), placental dysfunction causes the enhanced release of extracellular vesicle-derived miRNAs. The hypoxia-sensitive hsa-mir-210 is the most common PE-associated miRNA, but its exosomal profile has not been investigated. Objectives: Our aims were to measure exosomal total-miRNA concentration and to perform expression analysis of circulating exosomal hsa-miR-210 in women affected by chronic hypertension (CHT) gestational hypertension (GHT) or PE. Materials and methods: We collected plasma samples from women with CHT, GHT, PE (moderate: mPE and severe: sPE) and from normotensive pregnancies. Exosomal miRNAs were extracted and miRNA concentration was measured. RT-PCR was carried out with hsa-miR-210-3p-specific primers and relative expression was calculated using the comparative Ct method. Results: The total-miRNA concentration was different in the disease subgroups, and was significantly higher in mPE and sPE compared to the other groups. We found a significant difference in the relative exosomal hsa-miR-210-3p expression between all hypertensive groups compared to the normotensive samples, but significant upregulation was only observed in case of mPE and sPE patients. Both the level of total-miRNA and hsa-miR-210 expression was higher in case of severe PE. Conclusions: The level of circulating exosomal total-miRNA and hsa-miR-210 was elevated in women with PE, and it was higher in the severe form. We showed that hsa-miR-210 is secreted via exosomes, which may have a role in the pathomechanism of the disease. © 2017 International Society for the Study of Hypertension in Pregnancy.},
	keywords = {PREECLAMPSIA; microRNA; exosome; Maternal circulation},
	year = {2017},
	eissn = {2210-7797},
	pages = {207-212},
	orcid-numbers = {Biró, Orsolya/0000-0002-4300-3602; Alasztics, Bálint/0000-0002-4011-8439; Molvarec, Attila/0000-0002-3229-3034; Joó, József Gábor/0000-0001-9820-6514; Nagy, Bálint/0000-0002-0295-185X; Rigó, János/0000-0003-2762-6516}
}

@article{MTMT:3079514,
	title = {Extracellular vesicles in blood, milk and body fluids of the female and male urogenital tract and with special regard to reproduction},
	url = {https://m2.mtmt.hu/api/publication/3079514},
	author = {Foster, BP and Balassa, Tímea and Benen, TD and Dominovic, M and Elmadjian, GK and Florova, V and Fransolet, MD and Kestlerova, A and Kmiecik, G and Kostadinova, IA and Kyvelidou, C and Meggyes, Mátyás and Mincheva, MN and Moro, L and Pastuschek, J and Spoldi, V and Wandernoth, P and Weber, M and Toth, B and Markert, UR},
	doi = {10.1080/10408363.2016.1190682},
	journal-iso = {CRIT REV CL LAB SCI},
	journal = {CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES},
	volume = {53},
	unique-id = {3079514},
	issn = {1040-8363},
	abstract = {Extracellular vesicles (EVs) are released from almost all cells and tissues. They are able to transport substances (e.g. proteins, RNA or DNA) at higher concentrations than in their environment and may adhere in a receptor-controlled manner to specific cells or tissues in order to release their content into the respective target structure. Blood contains high concentrations of EVs mainly derived from platelets, and, at a smaller amount, from erythrocytes. The female and male reproductive tracts produce EVs which may be associated with fertility or infertility and are released into body fluids and mucosas of the urogenital organs. In this review, the currently relevant detection methods are presented and critically compared. During pregnancy, placenta-derived EVs are dynamically detectable in peripheral blood with changing profiles depending upon progress of pregnancy and different pregnancy-associated pathologies, such as preeclampsia. EVs offer novel non-invasive diagnostic tools which may reflect the situation of the placenta and the fetus. EVs in urine have the potential of reflecting urogenital diseases including cancers of the neighbouring organs. Several methods for detection, quantification and phenotyping of EVs have been established, which include electron microscopy, flow cytometry, ELISA-like methods, Western blotting, and analyses based on Brownian motion. This review article summarises the current knowledge about EVs in blood and cord blood, in the different compartments of the male and female reproductive tract, in trophoblast cells from normal and pre-eclamptic pregnancies, in placenta ex vivo perfusate, in the amniotic fluid, and in breast milk, as well as their potential effects on natural killer (NK) cells as possible targets.},
	year = {2016},
	eissn = {1549-781X},
	pages = {379-395}
}