TY  - JOUR
AU  - Zinman, Bernard
AU  - Wanner, Christoph
AU  - Lachin, John M
AU  - Fitchett, David
AU  - Bluhmki, Erich
AU  - Hantel, Stefan
AU  - Mattheus, Michaela
AU  - Devins, Theresa
AU  - Johansen, Odd Erik
AU  - Woerle, Hans J
AU  - Broedl, Uli C
AU  - Inzucchi, Silvio E
ED  - Aizenberg, D / Collaborator
ED  - Ulla, M / Collaborator
ED  - Waitman, J / Collaborator
ED  - De Loredo, L / Collaborator
ED  - Farías, J / Collaborator
ED  - Fideleff, H / Collaborator
ED  - Lagrutta, M / Collaborator
ED  - Maldonado, N / Collaborator
ED  - Colombo, H / Collaborator
ED  - Ferre Pacora, F / Collaborator
ED  - Wasserman, A / Collaborator
ED  - Maffei, L / Collaborator
ED  - Lehman, R / Collaborator
ED  - Selvanayagam, J / Collaborator
ED  - d’Emden, M / Collaborator
ED  - Fasching, P / Collaborator
ED  - Paulweber, B / Collaborator
ED  - Toplak, H / Collaborator
ED  - Luger, A / Collaborator
ED  - Drexel, H / Collaborator
ED  - Prager, R / Collaborator
ED  - Schnack, C / Collaborator
ED  - Schernthaner, G / Collaborator
ED  - Fliesser-Görzer, E / Collaborator
ED  - Kaser, S / Collaborator
ED  - Scheen, A / Collaborator
ED  - Van Gaal, L / Collaborator
ED  - Hollanders, G / Collaborator
ED  - Kockaerts, Y / Collaborator
ED  - Capiau, L / Collaborator
ED  - Chachati, A / Collaborator
ED  - Persu, A / Collaborator
ED  - Hermans, M / Collaborator
ED  - Vantroyen, D / Collaborator
ED  - Vercammen, C / Collaborator
ED  - Van de Borne, P / Collaborator
ED  - Benhalima, K / Collaborator
ED  - Mathieu, C / Collaborator
ED  - Lienart, F / Collaborator
ED  - Mortelmans, J / Collaborator
ED  - Strivay, M / Collaborator
ED  - Vereecken, G / Collaborator
ED  - Keymeulen, B / Collaborator
ED  - Lamkanfi, F / Collaborator
ED  - Chacra, A / Collaborator
ED  - Eliaschewitz, F / Collaborator
ED  - Zanella, M / Collaborator
ED  - Faludi, A / Collaborator
ED  - Bertolami, M / Collaborator
ED  - Hayashida, C / Collaborator
ED  - Nunes Salles, J / Collaborator
ED  - Monte, O / Collaborator
ED  - Dinato, M / Collaborator
ED  - Manenti, E / Collaborator
ED  - Rassi, N / Collaborator
ED  - Halpern, A / Collaborator
ED  - Lima Filho, M / Collaborator
ED  - Ayoub, J / Collaborator
ED  - Felicio, J / Collaborator
ED  - Borges, J / Collaborator
ED  - Gross, J / Collaborator
ED  - Sgarbi, J / Collaborator
ED  - Betti, R / Collaborator
ED  - Tiburcio, A / Collaborator
ED  - Purisch, S / Collaborator
ED  - Schmid, H / Collaborator
ED  - Takahashi, M / Collaborator
ED  - Castro, M / Collaborator
ED  - Rea, R / Collaborator
ED  - Hissa, M / Collaborator
ED  - Geloneze Neto, B / Collaborator
ED  - Saraiva, J / Collaborator
ED  - Henein, S / Collaborator
ED  - Lochnan, H / Collaborator
ED  - Imran, S A / Collaborator
ED  - Clayton, D / Collaborator
ED  - Bayly, K / Collaborator
ED  - Berlingieri, J / Collaborator
ED  - Boucher, P / Collaborator
ED  - Chan, Y / Collaborator
ED  - Gupta, M / Collaborator
ED  - Chehayeb, R / Collaborator
ED  - Ouellett, A / Collaborator
ED  - Ur, E / Collaborator
ED  - Woo, V / Collaborator
ED  - St Amour, E / Collaborator
ED  - Terront Lozano, M / Collaborator
ED  - Yupanqui Lozno, H / Collaborator
ED  - Urina, M / Collaborator
ED  - Lopez Jaramillo, P / Collaborator
ED  - Jaramillo, N / Collaborator
ED  - Sanchez, G / Collaborator
ED  - Pérez, G / Collaborator
ED  - Tusek, S / Collaborator
ED  - Mirosevic, G / Collaborator
ED  - Goldoni, V / Collaborator
ED  - Jurisic-Erzen, D / Collaborator
ED  - Balasko, A / Collaborator
ED  - Balic, S / Collaborator
ED  - Drvodelic-Sunic, E / Collaborator
ED  - Canecki-Varzic, Silvija / Collaborator
ED  - Machkova, M / Collaborator
ED  - Weiner, P / Collaborator
ED  - Lastuvka, J / Collaborator
ED  - Olsovsky, J / Collaborator
ED  - Krarup, T / Collaborator
ED  - Ridderstråle, M / Collaborator
ED  - Tarnow, L / Collaborator
ED  - Sætre Lihn, A / Collaborator
ED  - Christensen, P / Collaborator
ED  - Juhl, H / Collaborator
ED  - Urhammer, S / Collaborator
ED  - Lund, P / Collaborator
ED  - Adojaan, B / Collaborator
ED  - Jakovlev, Ü / Collaborator
ED  - Lanno, R / Collaborator
ED  - Lubi, M / Collaborator
ED  - Marandi, T / Collaborator
ED  - Gouet, D / Collaborator
ED  - Courrèges, J / Collaborator
ED  - Zaoui, P / Collaborator
ED  - Choukroun, G / Collaborator
ED  - Petit, C / Collaborator
ED  - Formagne, L / Collaborator
ED  - Estour, B / Collaborator
ED  - Mabire, P / Collaborator
ED  - Daugenet, C / Collaborator
ED  - Lemarie, B / Collaborator
ED  - Clavel, S / Collaborator
ED  - Aure, P / Collaborator
ED  - Remaud, P / Collaborator
ED  - Halimi, J / Collaborator
ED  - Hadjadj, S / Collaborator
ED  - Couffinhal, T / Collaborator
ED  - Glonti, S / Collaborator
ED  - Metreveli, D / Collaborator
ED  - Lominadze, Z / Collaborator
ED  - Giorgadze, E / Collaborator
ED  - Burtchuladze, T / Collaborator
ED  - Javashvili, L / Collaborator
ED  - Kurashvili, G / Collaborator
ED  - Kurashvili, R / Collaborator
ED  - Virsaladze, D / Collaborator
ED  - Nadareishvili, L / Collaborator
ED  - Khomasuridze, A / Collaborator
ED  - Cahill, T / Collaborator
ED  - Green, F / Collaborator
ED  - MacRury, S / Collaborator
ED  - Waldron, M / Collaborator
ED  - Middleton, A / Collaborator
ED  - McKnight, J / Collaborator
ED  - Pearson, E / Collaborator
ED  - Butler, M / Collaborator
ED  - Choksi, M / Collaborator
ED  - Caldwell, I / Collaborator
ED  - Farmer, I / Collaborator
ED  - Wyatt, N / Collaborator
ED  - Patrick, J / Collaborator
ED  - O'Brien, I / Collaborator
ED  - Devers, M / Collaborator
ED  - Bousboulas, S / Collaborator
ED  - Pappas, S / Collaborator
ED  - Piaditis, G / Collaborator
ED  - Vryonidou, A / Collaborator
ED  - Tentolouris, N / Collaborator
ED  - Karamitsos, K / Collaborator
ED  - Manes, C / Collaborator
ED  - Benroubi, M / Collaborator
ED  - Avramidis, I / Collaborator
ED  - Ozaki, R / Collaborator
ED  - Tan, K / Collaborator
ED  - Siu, S / Collaborator
ED  - Ip, T / Collaborator
ED  - Tsang, C / Collaborator
ED  - Dudas, M / Collaborator
ED  - Nagy, K / Collaborator
ED  - Salamon, C / Collaborator
ED  - Gerő, László / Collaborator
ED  - Patkay, J / Collaborator
ED  - Tabák, Ádám / Collaborator
ED  - Tamas, G / Collaborator
ED  - Juhasz, F / Collaborator
ED  - Szentpeteri, I / Collaborator
ED  - Ghaisas, N / Collaborator
ED  - Bantwal, G / Collaborator
ED  - Mohan, V / Collaborator
ED  - Gupta, J / Collaborator
ED  - Sadhu, N / Collaborator
ED  - Kulkarni, A / Collaborator
ED  - Garg, N / Collaborator
ED  - Reddy, S / Collaborator
ED  - Deshpande, N / Collaborator
ED  - Gutlapalli, K / Collaborator
ED  - Pillai, M / Collaborator
ED  - Premchand, R / Collaborator
ED  - Badgandi, M / Collaborator
ED  - Jain, S / Collaborator
ED  - Aravind, S / Collaborator
ED  - Shamanna, P / Collaborator
ED  - Pandey, A / Collaborator
ED  - Gupta, S / Collaborator
ED  - Pramono, B / Collaborator
ED  - Dante Saksono, H / Collaborator
ED  - Agung, P / Collaborator
ED  - Djoko Wahono, S / Collaborator
ED  - Suastika, K / Collaborator
ED  - Tanggo, Y / Collaborator
ED  - Juwana, Y / Collaborator
ED  - Siswanto, B / Collaborator
ED  - Adawi, F / Collaborator
ED  - Efrati, S / Collaborator
ED  - Mazen, E / Collaborator
ED  - Bashkin, A / Collaborator
ED  - Herskovits, T / Collaborator
ED  - Jaffe, A / Collaborator
ED  - Schiff, E / Collaborator
ED  - Wainstein, J / Collaborator
ED  - Taddei, S / Collaborator
ED  - Aiello, A / Collaborator
ED  - Arca, M / Collaborator
ED  - Calabro, P / Collaborator
ED  - Cignarelli, M / Collaborator
ED  - Fioretto, P / Collaborator
ED  - Marchesini Reggiani, G / Collaborator
ED  - Gnasso, A / Collaborator
ED  - Marchionni, N / Collaborator
ED  - Marsilii, A / Collaborator
ED  - Bucci, M / Collaborator
ED  - Mezzetti, A / Collaborator
ED  - Pozzilli, P / Collaborator
ED  - Colivicchi, F / Collaborator
ED  - Santini, M / Collaborator
ED  - Moro, E / Collaborator
ED  - Semplicini, A / Collaborator
ED  - Toscano, V / Collaborator
ED  - Fucili, A / Collaborator
ED  - Monno, S / Collaborator
ED  - Furui, K / Collaborator
ED  - Higashiue, S / Collaborator
ED  - Hiramatsu, N / Collaborator
ED  - Kawamitsu, K / Collaborator
ED  - Takenaka, T / Collaborator
ED  - Takahashi, H / Collaborator
ED  - Hojo, F / Collaborator
ED  - Onishi, Y / Collaborator
ED  - Izumino, K / Collaborator
ED  - Okubo, M / Collaborator
ED  - Wakida, Y / Collaborator
ED  - Kondo, Y / Collaborator
ED  - Hieshima, K / Collaborator
ED  - Jinnouchi, H / Collaborator
ED  - Suzuki, A / Collaborator
ED  - Ito, M / Collaborator
ED  - Park, S / Collaborator
ED  - Kim, Y / Collaborator
ED  - Hong, T / Collaborator
ED  - Park, H / Collaborator
ED  - Gwon, H / Collaborator
ED  - Kim, H / Collaborator
ED  - Kang, K / Collaborator
ED  - Lee, S / Collaborator
ED  - Jeong, M / Collaborator
ED  - Seung, K / Collaborator
ED  - Lim, D / Collaborator
ED  - Rha, S / Collaborator
ED  - Tahk, S / Collaborator
ED  - Yang, J / Collaborator
ED  - Yoon, J / Collaborator
ED  - Shin, M / Collaborator
ED  - Kim, D / Collaborator
ED  - Jeong, J / Collaborator
ED  - Nik Ahmad, N / Collaborator
ED  - Mustafa, N / Collaborator
ED  - Wan Mohamed, W / Collaborator
ED  - Fung, Y / Collaborator
ED  - Abdul Ghani, R / Collaborator
ED  - Chandramouli, A / Collaborator
ED  - Chee, K / Collaborator
ED  - Abdul Kadir, K / Collaborator
ED  - Ling, K / Collaborator
ED  - Abu Hassan, M / Collaborator
ED  - Foo, S / Collaborator
ED  - Garcia Hernandez, P / Collaborator
ED  - Aguilar-Salinas, C / Collaborator
ED  - Vidrio Velazquez, M / Collaborator
ED  - Flores, F / Collaborator
ED  - Alpizar Salazar, M / Collaborator
ED  - Micher Escalante, D / Collaborator
ED  - Garcia Soria, M / Collaborator
ED  - Cardona Muñoz, E / Collaborator
ED  - Storms, G / Collaborator
ED  - Schaper, N / Collaborator
ED  - Kooy, A / Collaborator
ED  - Krekels, M / Collaborator
ED  - vab Bemmel, T / Collaborator
ED  - Verhoeven, R / Collaborator
ED  - Mulder, H / Collaborator
ED  - Oldenburg-Ligtenberg, P / Collaborator
ED  - Gonkel, F / Collaborator
ED  - de Jong, A / Collaborator
ED  - van Soest, J / Collaborator
ED  - Viergever, P / Collaborator
ED  - Mevissen, H / Collaborator
ED  - Lochorn, G / Collaborator
ED  - Zwiers, G / Collaborator
ED  - Hoogslag, P / Collaborator
ED  - Ronner, E / Collaborator
ED  - Nierop, P / Collaborator
ED  - Al-Windy, N / Collaborator
ED  - Kragten, J / Collaborator
ED  - Dekelver, P / Collaborator
ED  - Benatar, J / Collaborator
ED  - Krebs, J / Collaborator
ED  - Scott, R / Collaborator
ED  - Heggen, E / Collaborator
ED  - Berz, A / Collaborator
ED  - Fossum, C / Collaborator
ED  - Hurtig, U / Collaborator
ED  - Langslet, G / Collaborator
ED  - Baranowski, M / Collaborator
ED  - Sparby, J / Collaborator
ED  - Karlsson, T / Collaborator
ED  - Delgado Torres, C / Collaborator
ED  - Rodriguez Escudero, A / Collaborator
ED  - Lisson, R / Collaborator
ED  - Allemant Maldonado, A / Collaborator
ED  - Gallardo Rojas, W / Collaborator
ED  - Gonzales Bravo, L / Collaborator
ED  - Lema Osores, J / Collaborator
ED  - Farfan, J / Collaborator
ED  - Zapata, L / Collaborator
ED  - Godoy Junchaya, J / Collaborator
ED  - Roldan Concha, Y / Collaborator
ED  - Urquiaga Calderon, J / Collaborator
ED  - Sy, R / Collaborator
ED  - Tan, G / Collaborator
ED  - Aquitania, G / Collaborator
ED  - De Los Santos, G / Collaborator
ED  - Panelo, A / Collaborator
ED  - Roderos, O / Collaborator
ED  - Rosales, R / Collaborator
ED  - Toledo, R / Collaborator
ED  - Liwag, A / Collaborator
ED  - Ramoncito, H / Collaborator
ED  - Skokowska, E / Collaborator
ED  - Krzyzagorska, E / Collaborator
ED  - Ogorek, M / Collaborator
ED  - Wojnowski, L / Collaborator
ED  - Spyra, J / Collaborator
ED  - Konieczny, M / Collaborator
ED  - Piesiewicz, W / Collaborator
ED  - Kus, W / Collaborator
ED  - Ocicka-Kozakiewicz, A / Collaborator
ED  - Orlowska-Kunikowska, E / Collaborator
ED  - Zmuda, W / Collaborator
ED  - Duarte, S / Collaborator
ED  - Leitão, A / Collaborator
ED  - Monteiro, P / Collaborator
ED  - Rita, H / Collaborator
ED  - Salgado, V / Collaborator
ED  - Pinto, L / Collaborator
ED  - Queirós, J / Collaborator
ED  - Teixeira, J / Collaborator
ED  - Rogado, C / Collaborator
ED  - Duarte, R / Collaborator
ED  - Sobral do Rosário, F / Collaborator
ED  - Silva, A / Collaborator
ED  - Andrade, L / Collaborator
ED  - Velez, M / Collaborator
ED  - Brazão, M / Collaborator
ED  - Istratoaie, O / Collaborator
ED  - Lichiardopol, R / Collaborator
ED  - Catrinoiu, D / Collaborator
ED  - Militaru, C / Collaborator
ED  - Zetu, C / Collaborator
ED  - Barbonta, D / Collaborator
ED  - Cosma, D / Collaborator
ED  - Crisan, C / Collaborator
ED  - Pop, L / Collaborator
ED  - Esip, V / Collaborator
ED  - Arutyunov, G / Collaborator
ED  - Boyarkin, M / Collaborator
ED  - Agafyina, A / Collaborator
ED  - Vorokhobina, N / Collaborator
ED  - Petunina, N / Collaborator
ED  - Libov, I / Collaborator
ED  - Zalevskaya, A / Collaborator
ED  - Nikolaev, K / Collaborator
ED  - Barbarash, O / Collaborator
ED  - Potemkin, V / Collaborator
ED  - Bystrova, A / Collaborator
ED  - Krasilnikova, E / Collaborator
ED  - Barbarich, V / Collaborator
ED  - Chumakova, G / Collaborator
ED  - Tarasov, N / Collaborator
ED  - Meleshkevich, T / Collaborator
ED  - Zateyshchikov, D / Collaborator
ED  - Lantseva, O / Collaborator
ED  - Belenkiy, D / Collaborator
ED  - Obrezan, A / Collaborator
ED  - Rossolko, L / Collaborator
ED  - Fillipova, E / Collaborator
ED  - Yakhontova, P / Collaborator
ED  - Khokhlov, A / Collaborator
ED  - Tan, R / Collaborator
ED  - Sum, C / Collaborator
ED  - Chang, H / Collaborator
ED  - Distiller, L / Collaborator
ED  - Pretorius, M / Collaborator
ED  - Nortje, H / Collaborator
ED  - Mitha, E / Collaborator
ED  - Burgess, L / Collaborator
ED  - Blignaut, S / Collaborator
ED  - Venter, T / Collaborator
ED  - Moodley, R / Collaborator
ED  - Lombaard, J / Collaborator
ED  - Govind, U / Collaborator
ED  - Naidoo, V / Collaborator
ED  - Mookadam, M / Collaborator
ED  - Engelbrecht, J / Collaborator
ED  - Omar, M / Collaborator
ED  - Jurgens, J / Collaborator
ED  - Podgorski, G / Collaborator
ED  - Vawda, H / Collaborator
ED  - Naidoo, D / Collaborator
ED  - Emanuel, S / Collaborator
ED  - Roodt, A / Collaborator
ED  - Amod, A / Collaborator
ED  - Van Zyl, L / Collaborator
ED  - Segura, J / Collaborator
ED  - Brito, M / Collaborator
ED  - Fernandez-Cruz, A / Collaborator
ED  - Artola, S / Collaborator
ED  - Iglesias, R / Collaborator
ED  - Toural, E / Collaborator
ED  - Garcia-Ortiz, L / Collaborator
ED  - Saban, J / Collaborator
ED  - Mesa, J / Collaborator
ED  - Vidal, J / Collaborator
ED  - Linares, J / Collaborator
ED  - del Cañizo, F / Collaborator
ED  - Rigla, M / Collaborator
ED  - Suarez, C / Collaborator
ED  - Llorente, I / Collaborator
ED  - Moreno, B / Collaborator
ED  - Antoli, A / Collaborator
ED  - Gomez Peralta, F / Collaborator
ED  - Iglesias, M / Collaborator
ED  - Pereg, V / Collaborator
ED  - de Teresa, L / Collaborator
ED  - Camafort, M / Collaborator
ED  - Trescoli, C / Collaborator
ED  - Satarasinghe, R / Collaborator
ED  - Somasundaram, N / Collaborator
ED  - Siyambalapitiya, S / Collaborator
ED  - Antonypillai, C / Collaborator
ED  - Bulugahapitiya, D / Collaborator
ED  - Medagama, U / Collaborator
ED  - Huang, C / Collaborator
ED  - Lu, Y / Collaborator
ED  - Hwang, J / Collaborator
ED  - Chiang, C / Collaborator
ED  - Wen, M / Collaborator
ED  - Chen, J / Collaborator
ED  - Lai, W / Collaborator
ED  - Chang, K / Collaborator
ED  - Wang, J / Collaborator
ED  - Yeh, H / Collaborator
ED  - Kriangsak, P / Collaborator
ED  - Deerochanawong, C / Collaborator
ED  - Suwanwalaikorn, S / Collaborator
ED  - Mangklabruks, A / Collaborator
ED  - Kaewsuwanna, P / Collaborator
ED  - Piyayotai, D / Collaborator
ED  - Iabluchanskyi, M / Collaborator
ED  - Samoylov, O / Collaborator
ED  - Godlevska, O / Collaborator
ED  - Kovalyova, O / Collaborator
ED  - Voloshyna, O / Collaborator
ED  - Tseluyko, V / Collaborator
ED  - Zotov, S / Collaborator
ED  - Vykhovanyuk, I / Collaborator
ED  - Dulgeroff, A / Collaborator
ED  - Mayfield, R / Collaborator
ED  - Zaniewski-Singh, M / Collaborator
ED  - Ullal, J / Collaborator
ED  - Aloi, J / Collaborator
ED  - De La Rosa, R / Collaborator
ED  - Mosely, J / Collaborator
ED  - Wittmer, B / Collaborator
ED  - Aronoff, S / Collaborator
ED  - Rosenfeld, J / Collaborator
ED  - Seidner, M / Collaborator
ED  - Warren, M / Collaborator
ED  - Fishman, N / Collaborator
ED  - Weiss, R / Collaborator
ED  - Arif, A / Collaborator
ED  - Sandberg, M / Collaborator
ED  - Lewis, D / Collaborator
ED  - Ball, E / Collaborator
ED  - Graf, R / Collaborator
ED  - Breton, C / Collaborator
ED  - Tamayo, R / Collaborator
ED  - Richards, R / Collaborator
ED  - Cefalu, W / Collaborator
ED  - Uwaifo, G / Collaborator
ED  - Zayour, D / Collaborator
ED  - Hoffman, J / Collaborator
ED  - Fitz-Patrick, D / Collaborator
ED  - Khan, B / Collaborator
ED  - Blaze, K / Collaborator
ED  - Bressler, P / Collaborator
ED  - Halpern, S / Collaborator
ED  - Chappell, D / Collaborator
ED  - Bergenstal, R / Collaborator
ED  - Cuddihy, R / Collaborator
ED  - Matfin, G / Collaborator
ED  - Freedman, Z / Collaborator
ED  - Gonzalez-Campoy, J / Collaborator
ED  - Lerman, S / Collaborator
ED  - Rendell, M / Collaborator
ED  - Sitar, S / Collaborator
ED  - Reeves, M / Collaborator
ED  - Howard, T / Collaborator
ED  - Soufer, J / Collaborator
ED  - Miranda-Palma, B / Collaborator
ED  - Laliotis, A / Collaborator
ED  - Shomali, M / Collaborator
ED  - Teltser, M / Collaborator
ED  - Hurley, D / Collaborator
ED  - Morawski, E / Collaborator
ED  - Cherlin, R / Collaborator
ED  - Houchin, V / Collaborator
ED  - Welch, M / Collaborator
ED  - Goytia-Leos, D / Collaborator
ED  - Syed, M / Collaborator
ED  - Kowaloff, E / Collaborator
ED  - Weinrauch, L / Collaborator
ED  - Peniston, J / Collaborator
ED  - Brockmyre, A / Collaborator
ED  - First, B / Collaborator
ED  - Feld, L / Collaborator
ED  - Huffman, D / Collaborator
ED  - Nassim, O / Collaborator
ED  - Gottschlich, G / Collaborator
ED  - Patel, A / Collaborator
ED  - Knopke, C / Collaborator
ED  - Hernandez, M / Collaborator
ED  - Diaz, J / Collaborator
ED  - Giugliano, G / Collaborator
ED  - Nicasio, J / Collaborator
ED  - Eagerton, D / Collaborator
ED  - Huntley, R / Collaborator
ED  - Reed, J / Collaborator
ED  - Magee, M / Collaborator
ED  - Hippert, R / Collaborator
ED  - Sofley, C / Collaborator
ED  - Alzohaili, O / Collaborator
ED  - Levins, P / Collaborator
ED  - Anspach, R / Collaborator
ED  - Shah, S / Collaborator
ED  - Brusco, O / Collaborator
ED  - Naidu, J / Collaborator
ED  - Lindenbaum, J / Collaborator
ED  - Jacks, R / Collaborator
ED  - Hammond, G / Collaborator
ED  - Arena, C / Collaborator
ED  - Saxman, K / Collaborator
ED  - Mach, M / Collaborator
ED  - Kerstein, H / Collaborator
ED  - Kereiakes, D / Collaborator
ED  - Wahlen, J / Collaborator
ED  - Wehmeier, K / Collaborator
ED  - Chaykin, L / Collaborator
ED  - Rothman, J / Collaborator
ED  - Fogelfeld, L / Collaborator
ED  - Stroger, J / Collaborator
ED  - Bittar, N / Collaborator
ED  - Rosenstock, J / Collaborator
ED  - Kayne, D / Collaborator
ED  - Navarro, J / Collaborator
ED  - Colfer, H / Collaborator
ED  - Mokshagundam, S / Collaborator
ED  - Shandilya, L / Collaborator
ED  - Connery, L / Collaborator
ED  - Wysham, C / Collaborator
ED  - Dela Llana, A / Collaborator
ED  - Jardula, M / Collaborator
ED  - MacAdams, M / Collaborator
ED  - Flippo, G / Collaborator
ED  - Heurich, E / Collaborator
ED  - Curtis, C / Collaborator
ED  - Sanders, D / Collaborator
ED  - Rawls, R / Collaborator
ED  - Velazquez, F / Collaborator
ED  - Osea, E / Collaborator
ED  - Mahood, K / Collaborator
ED  - Feldman, G / Collaborator
ED  - Eder, F / Collaborator
ED  - Riley, E / Collaborator
ED  - Jain, M / Collaborator
ED  - Fowler, W / Collaborator
ED  - Shepard, M / Collaborator
ED  - Schear, M / Collaborator
ED  - Barker, B / Collaborator
ED  - Strout, C / Collaborator
ED  - Obiekwe, O / Collaborator
ED  - Shanik, M / Collaborator
ED  - Green, C / Collaborator
ED  - Blakney, E / Collaborator
ED  - Roberson, K / Collaborator
ED  - Bretton, E / Collaborator
ED  - Pish, R / Collaborator
ED  - Kaveh, K / Collaborator
ED  - Maynard, B / Collaborator
ED  - Barager, W / Collaborator
ED  - Soldyshev, R / Collaborator
ED  - Austin, B / Collaborator
ED  - Parmar, P / Collaborator
ED  - Simpson, R / Collaborator
ED  - Chauhan, A / Collaborator
ED  - Kasper, J / Collaborator
ED  - Burr, R / Collaborator
ED  - Patel, N / Collaborator
ED  - Mariano, H / Collaborator
ED  - Pluto, T / Collaborator
ED  - Bratcher, C / Collaborator
ED  - Juarez, M / Collaborator
ED  - Levinson, L / Collaborator
ED  - Awad, A / Collaborator
ED  - Longshaw, K / Collaborator
ED  - Hoffman, K / Collaborator
ED  - Richwine, R / Collaborator
ED  - Molter, D / Collaborator
ED  - Boscia, J / Collaborator
ED  - Kowalyk, S / Collaborator
ED  - Lemis, P / Collaborator
ED  - Liss, J / Collaborator
ED  - Orr, R / Collaborator
ED  - Riser, J / Collaborator
ED  - Wood, J / Collaborator
ED  - Ubani, A / Collaborator
ED  - Paine, W / Collaborator
ED  - Hassani, F / Collaborator
ED  - Miranda, F / Collaborator
ED  - Hansen, V / Collaborator
ED  - Farris, N / Collaborator
ED  - Bowden, R / Collaborator
ED  - Ajani, D / Collaborator
ED  - Maw, K / Collaborator
ED  - Andersen, J / Collaborator
ED  - Bergman, B / Collaborator
ED  - Dunmyer, S / Collaborator
ED  - Brandon, D / Collaborator
ED  - Anderson, M / Collaborator
ED  - Bononi, P / Collaborator
ED  - Prawer, J / Collaborator
ED  - Seidman, B / Collaborator
ED  - Cruz, H / Collaborator
ED  - Wilks, K / Collaborator
ED  - DiSanto, L / Collaborator
ED  - Buynak, R / Collaborator
ED  - Christensen, T / Collaborator
ED  - Denker, P / Collaborator
ED  - Koppel, W / Collaborator
ED  - Stedman, M / Collaborator
ED  - Lewy-Alterbaum, L / Collaborator
ED  - Karim, S / Collaborator
ED  - Shapiro, J / Collaborator
ED  - Gardner, T / Collaborator
ED  - Oskin, T / Collaborator
ED  - Gabra, N / Collaborator
ED  - Malano, J / Collaborator
ED  - Welty, Francine K / Collaborator
ED  - Parhofer, Klaus G / Collaborator
ED  - Pedersen, Terje R / Collaborator
ED  - Lees, Kennedy R / Collaborator
ED  - Clayton, Tim / Collaborator
ED  - Pocock, Stuart / Collaborator
ED  - Palmer, Mike / Collaborator
ED  - Clemmensen, Peter / Collaborator
ED  - Grande, Peer / Collaborator
ED  - Pehrson, Steen / Collaborator
ED  - Januzzi, James / Collaborator
ED  - Wood, Malissa J / Collaborator
ED  - Petrie, Mark / Collaborator
ED  - Sairanen, Tiina / Collaborator
ED  - Tatlisumak, Turgut / Collaborator
ED  - Soinne, Lauri / Collaborator
ED  - Kase, Carlos / Collaborator
ED  - Turan, Tanya / Collaborator
ED  - Watkins, Paul / Collaborator
ED  - Lewis, James / Collaborator
ED  - Freston, James / Collaborator
ED  - Schenker, Steven / Collaborator
ED  - Heist, Rebecca / Collaborator
ED  - Lee, Richard J / Collaborator
ED  - Natale, Ronald B / Collaborator
ED  - Sullivan, Ryan J / Collaborator
ED  - Buchbinder, Elizabeth I / Collaborator
ED  - Chodak, Gerald / Collaborator
ED  - Schumacher, Martin / Collaborator
ED  - Schmoor, Claudia / Collaborator
ED  - Hieke, Stefanie / Collaborator
ED  - Ohneberg, Kristin / Collaborator
TI  - Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.
JF  - NEW ENGLAND JOURNAL OF MEDICINE
J2  - NEW ENGL J MED
VL  - 373
PY  - 2015
IS  - 22
SP  - 2117
EP  - 2128
PG  - 12
SN  - 0028-4793
DO  - 10.1056/NEJMoa1504720
UR  - https://m2.mtmt.hu/api/publication/33698770
ID  - 33698770
AB  - The effects of empagliflozin, an inhibitor of sodium-glucose cotransporter 2, in addition to standard care, on cardiovascular morbidity and mortality in patients with type 2 diabetes at high cardiovascular risk are not known.We randomly assigned patients to receive 10 mg or 25 mg of empagliflozin or placebo once daily. The primary composite outcome was death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke, as analyzed in the pooled empagliflozin group versus the placebo group. The key secondary composite outcome was the primary outcome plus hospitalization for unstable angina.A total of 7020 patients were treated (median observation time, 3.1 years). The primary outcome occurred in 490 of 4687 patients (10.5%) in the pooled empagliflozin group and in 282 of 2333 patients (12.1%) in the placebo group (hazard ratio in the empagliflozin group, 0.86; 95.02% confidence interval, 0.74 to 0.99; P=0.04 for superiority). There were no significant between-group differences in the rates of myocardial infarction or stroke, but in the empagliflozin group there were significantly lower rates of death from cardiovascular causes (3.7%, vs. 5.9% in the placebo group; 38% relative risk reduction), hospitalization for heart failure (2.7% and 4.1%, respectively; 35% relative risk reduction), and death from any cause (5.7% and 8.3%, respectively; 32% relative risk reduction). There was no significant between-group difference in the key secondary outcome (P=0.08 for superiority). Among patients receiving empagliflozin, there was an increased rate of genital infection but no increase in other adverse events.Patients with type 2 diabetes at high risk for cardiovascular events who received empagliflozin, as compared with placebo, had a lower rate of the primary composite cardiovascular outcome and of death from any cause when the study drug was added to standard care. (Funded by Boehringer Ingelheim and Eli Lilly; EMPA-REG OUTCOME ClinicalTrials.gov number, NCT01131676.).
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Parving, Hans-Henrik
AU  - Brenner, Barry M
AU  - McMurray, John J V
AU  - de Zeeuw, Dick
AU  - Haffner, Steven M
AU  - Solomon, Scott D
AU  - Chaturvedi, Nish
AU  - Persson, Frederik
AU  - Desai, Akshay S
AU  - Nicolaides, Maria
AU  - Richard, Alexia
AU  - Xiang, Zhihua
AU  - Brunel, Patrick
AU  - Pfeffer, Marc A
ED  - Viberti, Giancarlo / Collaborator
ED  - Lachin, John M / Collaborator
ED  - Zinman, Bernard / Collaborator
ED  - Pedersen, Terje R / Collaborator
ED  - Villamil, A S / Collaborator
ED  - Juncos, L / Collaborator
ED  - Prager, R / Collaborator
ED  - Verpooten, G / Collaborator
ED  - Zanella, M T / Collaborator
ED  - Leiter, L / Collaborator
ED  - Pan, C / Collaborator
ED  - Wang, H / Collaborator
ED  - Botero, R / Collaborator
ED  - Cifkova, R / Collaborator
ED  - Christiansen, J Sandahl / Collaborator
ED  - Groop, P-H / Collaborator
ED  - Marre, M / Collaborator
ED  - Haller, H / Collaborator
ED  - Nickenig, G / Collaborator
ED  - Siamopoulos, K / Collaborator
ED  - Gero, L / Collaborator
ED  - Maggioni, A / Collaborator
ED  - Remuzzi, G / Collaborator
ED  - Katayama, S Shigenhiro / Collaborator
ED  - Kim, S-G / Collaborator
ED  - Petrulioniene, Z / Collaborator
ED  - Lok, D / Collaborator
ED  - Kooy, A / Collaborator
ED  - Jorde, R / Collaborator
ED  - Medina, F / Collaborator
ED  - Polonia, J / Collaborator
ED  - Wong, K-S / Collaborator
ED  - Dukat, A / Collaborator
ED  - Rayner, B L / Collaborator
ED  - Ruilope, L / Collaborator
ED  - Weiss, L / Collaborator
ED  - Wuethrich, R / Collaborator
ED  - Sheu, W / Collaborator
ED  - Sritara, P / Collaborator
ED  - Comlekci, A / Collaborator
ED  - Bilous, R / Collaborator
ED  - Toto, R / Collaborator
ED  - Jamerson, K / Collaborator
ED  - Carillo, E / Collaborator
ED  - Juncos, Luis / Collaborator
ED  - Orias, Marcelo / Collaborator
ED  - Kuschnir, Emilio / Collaborator
ED  - Rusculleda, Marcelo / Collaborator
ED  - Garcia, Sergio / Collaborator
ED  - Farias, Eduardo / Collaborator
ED  - Lema, Luis / Collaborator
ED  - Hominal, Miguel / Collaborator
ED  - Montaña, Oscar / Collaborator
ED  - Sala, Jorgelina / Collaborator
ED  - Diaz, Monica / Collaborator
ED  - Piskorz, Daniel / Collaborator
ED  - Vita, Nestor / Collaborator
ED  - Litwak, Leon / Collaborator
ED  - Sinay, Isaac / Collaborator
ED  - Marin, Marcos / Collaborator
ED  - Massari, Pablo / Collaborator
ED  - Majul, Claudio / Collaborator
ED  - Aizemberg, Diego / Collaborator
ED  - Azize, Guillermo Moises / Collaborator
ED  - Bartolacci, Ines / Collaborator
ED  - Reboredo, Ana / Collaborator
ED  - Vico, Marisa / Collaborator
ED  - Milesi, Ricardo / Collaborator
ED  - Sessa, Horacio / Collaborator
ED  - Wassermann, Alfredo / Collaborator
ED  - Margulis, Fernando / Collaborator
ED  - Zangroniz, Pedro / Collaborator
ED  - Watschinger, B / Collaborator
ED  - Prager, R / Collaborator
ED  - Toplak, H / Collaborator
ED  - Paulweber, B / Collaborator
ED  - Drexel, H / Collaborator
ED  - Francesconi, C / Collaborator
ED  - Foeger, B / Collaborator
ED  - Mayer, G / Collaborator
ED  - Braun, R K / Collaborator
ED  - Brath, H / Collaborator
ED  - Gaal, L V / Collaborator
ED  - Niepen, P V D / Collaborator
ED  - Persu, A / Collaborator
ED  - Vercammen, C / Collaborator
ED  - Vriese, A D / Collaborator
ED  - Coucke, F / Collaborator
ED  - Mathieu, C / Collaborator
ED  - Fery, F / Collaborator
ED  - Treille, S / Collaborator
ED  - Meeus, G / Collaborator
ED  - Acker, K V / Collaborator
ED  - Scheen, A / Collaborator
ED  - Tits, J / Collaborator
ED  - Ruige, J / Collaborator
ED  - Krzesinski, J-M / Collaborator
ED  - Hollanders, G / Collaborator
ED  - Liénart, F / Collaborator
ED  - Dendale, P / Collaborator
ED  - Quinonez, M / Collaborator
ED  - Arnouts, P / Collaborator
ED  - Vanuytsel, J / Collaborator
ED  - Zanella, M / Collaborator
ED  - Mion, D / Collaborator
ED  - Forti, A / Collaborator
ED  - Almeida, F / Collaborator
ED  - Cunha, R / Collaborator
ED  - de Paula, R B / Collaborator
ED  - Brandao, A / Collaborator
ED  - Rocha, J / Collaborator
ED  - Krieger, E / Collaborator
ED  - Feitosa, G / Collaborator
ED  - Saraiva, J / Collaborator
ED  - Martin, J / Collaborator
ED  - Hissa, M N / Collaborator
ED  - Schmid, H / Collaborator
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ED  - Oigman, W / Collaborator
ED  - Bowering, K / Collaborator
ED  - Garceau, C / Collaborator
ED  - Berlingieri, J C / Collaborator
ED  - Weisnagel, S J / Collaborator
ED  - Hardin, P / Collaborator
ED  - Powell, C / Collaborator
ED  - Turcot, R / Collaborator
ED  - Muirhead, N / Collaborator
ED  - Aronson, R / Collaborator
ED  - Barima, Y T / Collaborator
ED  - Steele, A W / Collaborator
ED  - Pandey, S / Collaborator
ED  - Woo, V / Collaborator
ED  - Cha, J / Collaborator
ED  - Dattani, D / Collaborator
ED  - Godin, C / Collaborator
ED  - Gupta, M / Collaborator
ED  - Leiter, L / Collaborator
ED  - Saunders, K / Collaborator
ED  - Tellier, G / Collaborator
ED  - Ting, R / Collaborator
ED  - Tobe, S / Collaborator
ED  - Chouinard, G / Collaborator
ED  - Schlosser, R / Collaborator
ED  - Khandwala, H / Collaborator
ED  - Ekoe, J M / Collaborator
ED  - Harris, S B / Collaborator
ED  - Pichette, V / Collaborator
ED  - Lachance, P / Collaborator
ED  - Ooi, T C / Collaborator
ED  - Tildesley, H / Collaborator
ED  - Barrett, B / Collaborator
ED  - Cournoyer, S / Collaborator
ED  - Lu, J / Collaborator
ED  - Zhang, H / Collaborator
ED  - Liu, X / Collaborator
ED  - Yan, S / Collaborator
ED  - Qi, X / Collaborator
ED  - Li, Q / Collaborator
ED  - Li, H / Collaborator
ED  - Lv, X / Collaborator
ED  - Yang, J / Collaborator
ED  - Sun, N / Collaborator
ED  - Xia, W / Collaborator
ED  - Wang, N / Collaborator
ED  - Tong, N / Collaborator
ED  - Mei, C / Collaborator
ED  - Gu, S / Collaborator
ED  - Zhang, J / Collaborator
ED  - Chen, X / Collaborator
ED  - Li, L / Collaborator
ED  - Su, B / Collaborator
ED  - Wang, L / Collaborator
ED  - Qiu, M / Collaborator
ED  - Wu, X / Collaborator
ED  - Liu, Z / Collaborator
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ED  - Xu, G / Collaborator
ED  - Dong, J / Collaborator
ED  - Zhu, D / Collaborator
ED  - Zhang, M / Collaborator
ED  - Yan, J / Collaborator
ED  - Liu, B / Collaborator
ED  - Chen, J / Collaborator
ED  - Fu, J / Collaborator
ED  - Yan, L / Collaborator
ED  - Zhan, X / Collaborator
ED  - Zhong, L / Collaborator
ED  - Yang, T / Collaborator
ED  - Ma, J / Collaborator
ED  - Xu, M / Collaborator
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ED  - Shi, B / Collaborator
ED  - Ji, Q / Collaborator
ED  - Zhong, H / Collaborator
ED  - He, R / Collaborator
ED  - Yuan, Z / Collaborator
ED  - Zhou, Z / Collaborator
ED  - Lin, H / Collaborator
ED  - Yang, W / Collaborator
ED  - Ke, Y / Collaborator
ED  - Li, Q / Collaborator
ED  - Hong, T / Collaborator
ED  - Franco, C / Collaborator
ED  - Casas, L / Collaborator
ED  - Triana, A / Collaborator
ED  - Botero, R / Collaborator
ED  - Jaramillo, C / Collaborator
ED  - Hernandez, E / Collaborator
ED  - Barrera, C / Collaborator
ED  - Blanco, D / Collaborator
ED  - Stipal, R / Collaborator
ED  - Widimsky, P / Collaborator
ED  - Dohnalova, L / Collaborator
ED  - Komroskova, M / Collaborator
ED  - Kvapil, M / Collaborator
ED  - Belobradkova, J / Collaborator
ED  - Tesar, V / Collaborator
ED  - Cifkova, R / Collaborator
ED  - Vodnansky, P / Collaborator
ED  - Kocourkova, B / Collaborator
ED  - Christiansen, J S / Collaborator
ED  - Lervang, H-H / Collaborator
ED  - Perrild, H / Collaborator
ED  - Rossing, P / Collaborator
ED  - Oestergaard, O / Collaborator
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ED  - Thorsteinsson, B / Collaborator
ED  - Snorgaard, O / Collaborator
ED  - Urhammer, S / Collaborator
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ED  - Strand, J / Collaborator
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ED  - Saari, M / Collaborator
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ED  - Aldigier, J-C / Collaborator
ED  - Zaoui, P / Collaborator
ED  - Fauvel, J-P / Collaborator
ED  - Gouet, D / Collaborator
ED  - Valensi, P-E / Collaborator
ED  - Charpentier, G / Collaborator
ED  - Marechaud, R / Collaborator
ED  - Penfornis, A / Collaborator
ED  - Ovize, M / Collaborator
ED  - Kovalchuck, A A / Collaborator
ED  - Haller, H / Collaborator
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ED  - Schoen, N / Collaborator
ED  - Groeschel, W / Collaborator
ED  - Eickhoff, F / Collaborator
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ED  - Zimmermann, U / Collaborator
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ED  - Vosskuehler, A / Collaborator
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ED  - Schax, U / Collaborator
ED  - Lehmann, G / Collaborator
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ED  - Klausmann, G / Collaborator
ED  - Adelberger, V / Collaborator
ED  - Gessner, S / Collaborator
ED  - Fiesselmann, A / Collaborator
ED  - Oerter, E / Collaborator
ED  - Hohenstatt, T / Collaborator
ED  - Groeschel, A / Collaborator
ED  - Behnke, T / Collaborator
ED  - Sisting, R T / Collaborator
ED  - Schoch, D / Collaborator
ED  - Bieler, T / Collaborator
ED  - Schleyer, S / Collaborator
ED  - Altes, U / Collaborator
ED  - Klepzig, C / Collaborator
ED  - Rudofsky, G / Collaborator
ED  - Mueller, G / Collaborator
ED  - Burkhardt, F / Collaborator
ED  - Reschke, K / Collaborator
ED  - Senftleber, I / Collaborator
ED  - Wiesweg, C K / Collaborator
ED  - Herrmann, H-J / Collaborator
ED  - Brandstetter, R / Collaborator
ED  - Segner, A / Collaborator
ED  - Nickenig, G / Collaborator
ED  - Schmitt, H / Collaborator
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ED  - Goebel, R / Collaborator
ED  - Schreibmueller, F / Collaborator
ED  - Pencz, I / Collaborator
ED  - Ott, P / Collaborator
ED  - Siamopoulos, K / Collaborator
ED  - Migdalis, I / Collaborator
ED  - Pappas, S / Collaborator
ED  - Pagkalos, E / Collaborator
ED  - Yalouris, A / Collaborator
ED  - Tsapas, A / Collaborator
ED  - Maltezos, E / Collaborator
ED  - Tentolouris, N / Collaborator
ED  - Papadakis, I / Collaborator
ED  - Ioannidis, G / Collaborator
ED  - Goumenos, D / Collaborator
ED  - Corona, V / Collaborator
ED  - Gonzalez, R / Collaborator
ED  - Haase, F / Collaborator
ED  - Monterroso, V / Collaborator
ED  - Sánchez, V / Collaborator
ED  - Turcios, E / Collaborator
ED  - Wyss, F / Collaborator
ED  - Arango, J L / Collaborator
ED  - Bako, B / Collaborator
ED  - Deak, L / Collaborator
ED  - Dömötör, E / Collaborator
ED  - Dudas, M / Collaborator
ED  - Fulop, T / Collaborator
ED  - Kiss, I / Collaborator
ED  - Koranyi, L / Collaborator
ED  - Lengyel, Zoltán / Collaborator
ED  - Nyirati, G / Collaborator
ED  - Oroszlan, T / Collaborator
ED  - Aniko, S / Collaborator
ED  - Vörös, P / Collaborator
ED  - Kapocsi, J / Collaborator
ED  - Wittmann, István / Collaborator
ED  - Paragh, G / Collaborator
ED  - Ábrahám, György / Collaborator
ED  - Tandon, N / Collaborator
ED  - Thomas, N / Collaborator
ED  - Mohan, V / Collaborator
ED  - Sahay, R / Collaborator
ED  - Sethi, B / Collaborator
ED  - Rao, V / Collaborator
ED  - Kumar, S / Collaborator
ED  - Chowdhury, S / Collaborator
ED  - Dharmalingam, M / Collaborator
ED  - Seshiah, V / Collaborator
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ED  - Viswanathan, V / Collaborator
ED  - Yajnik, C / Collaborator
ED  - Adhikari, P / Collaborator
ED  - Krishnan, U / Collaborator
ED  - Varthakavi, P / Collaborator
ED  - Hiremath, J / Collaborator
ED  - Bhattacharyya, A / Collaborator
ED  - Dani, S / Collaborator
ED  - Modi, K K / Collaborator
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ED  - Morosetti, M / Collaborator
ED  - Veglio, F / Collaborator
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ED  - Giordano, C / Collaborator
ED  - Novo, S / Collaborator
ED  - Santoro, A / Collaborator
ED  - Ferri, C / Collaborator
ED  - Capuano, V / Collaborator
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ED  - Tonolo, G / Collaborator
ED  - Villa, G / Collaborator
ED  - De Pellegrin, A / Collaborator
ED  - Zanette, G / Collaborator
ED  - Federici, M / Collaborator
ED  - Aucello, G / Collaborator
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ED  - Skeie, S / Collaborator
ED  - Istad, H / Collaborator
ED  - Skjelvan, G / Collaborator
ED  - Gronert, J / Collaborator
ED  - Tomala, T / Collaborator
ED  - Gudnason, S / Collaborator
ED  - Torvik, D Tarje / Collaborator
ED  - Risberg, K / Collaborator
ED  - Abedini, S / Collaborator
ED  - Cabrera, W / Collaborator
ED  - Medina, B / Collaborator
ED  - Medina, F / Collaborator
ED  - Herrada, B / Collaborator
ED  - Saavedra, A / Collaborator
ED  - Polonia, D Jorge / Collaborator
ED  - Providencia, D Luis / Collaborator
ED  - Carvalho, D / Collaborator
ED  - Vasconcelos, M P / Collaborator
ED  - da Silva, G F / Collaborator
ED  - Branco, P / Collaborator
ED  - Gil, D V / Collaborator
ED  - da Costa, A G / Collaborator
ED  - da Silva, P M / Collaborator
ED  - Arez, L / Collaborator
ED  - Martins, L / Collaborator
ED  - Birne, R / Collaborator
ED  - Dzuponova, J / Collaborator
ED  - Surovcikova, M / Collaborator
ED  - Culak, J / Collaborator
ED  - Dukat, A / Collaborator
ED  - Filipova, S / Collaborator
ED  - Andre, I / Collaborator
ED  - Stevlik, J / Collaborator
ED  - Uhliar, R / Collaborator
ED  - Fabryova, L / Collaborator
ED  - Benacka, J / Collaborator
ED  - Koleny, D / Collaborator
ED  - Szentivanyi, M / Collaborator
ED  - Spisak, V / Collaborator
ED  - Pella, D / Collaborator
ED  - Pastrnakova, E / Collaborator
ED  - Martinka, E / Collaborator
ED  - Chua, T / Collaborator
ED  - Wong, K S / Collaborator
ED  - Lau, T / Collaborator
ED  - Ng, T G / Collaborator
ED  - Yeoh, L Y / Collaborator
ED  - Bhana, S A / Collaborator
ED  - Rayner, B / Collaborator
ED  - Wellmann, H / Collaborator
ED  - Amod, A / Collaborator
ED  - Ranjith, N / Collaborator
ED  - Ahmed, F / Collaborator
ED  - Rheeder, P / Collaborator
ED  - Makan, H / Collaborator
ED  - Naicker, P / Collaborator
ED  - Podgorski, G / Collaborator
ED  - De Teresa, E / Collaborator
ED  - Olivan, J / Collaborator
ED  - Fernandez, V L / Collaborator
ED  - Povedano, S T / Collaborator
ED  - Terns, M / Collaborator
ED  - Ricart, W / Collaborator
ED  - Gonzalez, J M / Collaborator
ED  - Fernandez, P / Collaborator
ED  - Parreño, L de Teresa / Collaborator
ED  - Redon, J / Collaborator
ED  - Parra, J / Collaborator
ED  - Calvo, C / Collaborator
ED  - Lopez, I / Collaborator
ED  - Puig, J G / Collaborator
ED  - Calle, A / Collaborator
ED  - Garcia, J C F / Collaborator
ED  - Lopez, J M / Collaborator
ED  - Jimenez, M L / Collaborator
ED  - Fraile, B / Collaborator
ED  - Perez, J S / Collaborator
ED  - Nadal, J J / Collaborator
ED  - Guija, E / Collaborator
ED  - Calviño, J / Collaborator
ED  - Barrios, V / Collaborator
ED  - Iglesias, J N / Collaborator
ED  - Armario, P / Collaborator
ED  - Garcia, M / Collaborator
ED  - Aranda, P / Collaborator
ED  - Brotons, C / Collaborator
ED  - Ruilope, L / Collaborator
ED  - Gomez, P / Collaborator
ED  - Catelao, A M / Collaborator
ED  - Cusachs, A R / Collaborator
ED  - Sarro, M / Collaborator
ED  - Martinez, V / Collaborator
ED  - dell Valle, M H / Collaborator
ED  - Trias, F / Collaborator
ED  - Comas, A / Collaborator
ED  - Salvador, N / Collaborator
ED  - Martinez, F / Collaborator
ED  - Hernandez, F / Collaborator
ED  - Martinez, J / Collaborator
ED  - Mateos, C / Collaborator
ED  - Peral, J L / Collaborator
ED  - Tolosana, J / Collaborator
ED  - Sobrino, J / Collaborator
ED  - Isart, J / Collaborator
ED  - Vizcaino, J / Collaborator
ED  - Vega, F Fernandez / Collaborator
ED  - Zamorano, J L / Collaborator
ED  - Bacariza, M / Collaborator
ED  - Soubriet, A / Collaborator
ED  - Fernández-Cruz, A / Collaborator
ED  - Querejeta, R / Collaborator
ED  - Leira, V Muñoz / Collaborator
ED  - Iglesias, F E Calvo / Collaborator
ED  - Ibrik, O / Collaborator
ED  - Martin, D / Collaborator
ED  - Nanclares, M S / Collaborator
ED  - Mediavilla, J D / Collaborator
ED  - Galceran, J M / Collaborator
ED  - Lopez, A / Collaborator
ED  - Muros, T / Collaborator
ED  - Pascual, J / Collaborator
ED  - Casalla, F / Collaborator
ED  - Tornero, F / Collaborator
ED  - Fernandez, G / Collaborator
ED  - Weiss, L / Collaborator
ED  - Pettersson, P / Collaborator
ED  - Olsen, H / Collaborator
ED  - Franke, F / Collaborator
ED  - Stroembom, U / Collaborator
ED  - Furuland, H / Collaborator
ED  - Larnefelt, H / Collaborator
ED  - Allemann, Y / Collaborator
ED  - Krapf, R / Collaborator
ED  - Wuethrich, R / Collaborator
ED  - Gerber, P / Collaborator
ED  - Munger, R / Collaborator
ED  - Hayoz, D / Collaborator
ED  - Graf, H J / Collaborator
ED  - Burnier, M / Collaborator
ED  - Petrillo, A / Collaborator
ED  - Batt, R / Collaborator
ED  - Constam, E N / Collaborator
ED  - Moccetti, T / Collaborator
ED  - Bianda, T / Collaborator
ED  - Rickli, H / Collaborator
ED  - Bulliard, C / Collaborator
ED  - Wu, Kwan-Dun / Collaborator
ED  - Lin, Shih-Hua / Collaborator
ED  - Wu, Chih-Jen / Collaborator
ED  - Sheu, W Huey-Herng / Collaborator
ED  - Su, Shih-Li / Collaborator
ED  - Chen, Shih-Chueh / Collaborator
ED  - Chou, Chien-Wen / Collaborator
ED  - Lee, Chien-Te / Collaborator
ED  - Yang, Te-Cheng / Collaborator
ED  - Chen, Hung-Chun / Collaborator
ED  - Sritara, P / Collaborator
ED  - Sukonthasarn, A / Collaborator
ED  - Sriratanasathavorn, C / Collaborator
ED  - Eiam-Ong, S / Collaborator
ED  - Supasyndh, O / Collaborator
ED  - Chanchairujira, T / Collaborator
ED  - Kitiyakara, C / Collaborator
ED  - Comlekci, A / Collaborator
ED  - Arici, M / Collaborator
ED  - Usalan, C / Collaborator
ED  - Guneri, S / Collaborator
ED  - Koc, M / Collaborator
ED  - Kalender, B / Collaborator
ED  - Ates, K / Collaborator
ED  - Gurgun, C / Collaborator
ED  - Araz, M / Collaborator
ED  - Demirbas, B / Collaborator
ED  - Biernacki, W / Collaborator
ED  - Calvert, J / Collaborator
ED  - Eavis, P / Collaborator
ED  - Kerrane, J / Collaborator
ED  - Litchfield, J / Collaborator
ED  - Middleton, A / Collaborator
ED  - Roberts, J / Collaborator
ED  - Simpson, H / Collaborator
ED  - Charles, H / Collaborator
ED  - Jardine, A / Collaborator
ED  - Fisher, M / Collaborator
ED  - Banerjee, D / Collaborator
ED  - Gallen, I / Collaborator
ED  - Gnudi, L / Collaborator
ED  - Harvey, J / Collaborator
ED  - O'Hare, P / Collaborator
ED  - Vora, J / Collaborator
ED  - Winocour, P / Collaborator
ED  - Soran, H / Collaborator
ED  - Browne, D / Collaborator
ED  - Darko, D / Collaborator
ED  - Mancebo, J G / Collaborator
ED  - de Roa, E R / Collaborator
ED  - Antepara, N / Collaborator
ED  - Carrillo, E / Collaborator
ED  - Berrizbeitia, M / Collaborator
ED  - Guevara, L / Collaborator
ED  - Pernalete, N / Collaborator
ED  - Ontiveros, C / Collaborator
ED  - Zigrang, W / Collaborator
ED  - Blakney, Eric / Collaborator
ED  - Rosenblit, P / Collaborator
ED  - Weinstein, R / Collaborator
ED  - Klaff, L / Collaborator
ED  - Lipetz, R / Collaborator
ED  - Busick, E / Collaborator
ED  - Tung, P / Collaborator
ED  - Cooperman, M / Collaborator
ED  - Michael, S / Collaborator
ED  - Sun, C-Huan / Collaborator
ED  - Hart, T / Collaborator
ED  - Maddux, A / Collaborator
ED  - Bowden, R / Collaborator
ED  - East, C / Collaborator
ED  - Arakaki, R / Collaborator
ED  - Villafuerte, B / Collaborator
ED  - Mamish, Z / Collaborator
ED  - Mendez, R / Collaborator
ED  - Connery, L / Collaborator
ED  - Nour, K / Collaborator
ED  - Wynne, A / Collaborator
ED  - Busch, R / Collaborator
ED  - Zamora, B / Collaborator
ED  - Sachson, R / Collaborator
ED  - Prasad, J / Collaborator
ED  - Lasala, G / Collaborator
ED  - Smith, M / Collaborator
ED  - Fitz-Patrick, D / Collaborator
ED  - Ruiz-Rivera, L / Collaborator
ED  - Barranco, E / Collaborator
ED  - Solomon, R / Collaborator
ED  - Woolley, A / Collaborator
ED  - Brown, C / Collaborator
ED  - Freedman, Z / Collaborator
ED  - Schmidt, S / Collaborator
ED  - Pollock, J / Collaborator
ED  - Ruddy, M / Collaborator
ED  - Toto, R / Collaborator
ED  - Kopyt, N P / Collaborator
ED  - Bazzi, A / Collaborator
ED  - Horowitz, B / Collaborator
ED  - Feng, W / Collaborator
ED  - Wahl, T / Collaborator
ED  - Duprez, D / Collaborator
ED  - Gilbert, J / Collaborator
ED  - Steigerwalt, S / Collaborator
ED  - Jacqmein, J / Collaborator
ED  - Gorton, S / Collaborator
ED  - Allison, J / Collaborator
ED  - Pino, J / Collaborator
ED  - Lock, J / Collaborator
ED  - Leimbach, W / Collaborator
ED  - Anderson, J / Collaborator
ED  - Beacom, M / Collaborator
ED  - Craig, W / Collaborator
ED  - Gorson, D / Collaborator
ED  - Kerstein, H / Collaborator
ED  - Segal, S / Collaborator
ED  - Downey, H / Collaborator
ED  - Ledger, G / Collaborator
ED  - McGill, J / Collaborator
ED  - Gabriel, J / Collaborator
ED  - Nolen, T / Collaborator
ED  - Levinson, L / Collaborator
ED  - Williams, T / Collaborator
ED  - Levenson, D / Collaborator
ED  - Lerman, S / Collaborator
ED  - Minehart, C / Collaborator
ED  - Agarwal, N / Collaborator
ED  - Verma, Sl / Collaborator
ED  - Valitutto, M / Collaborator
ED  - Demetry, K / Collaborator
ED  - Mersey, J / Collaborator
ED  - Koeper, D / Collaborator
ED  - Fanti, P / Collaborator
ED  - Eng, G / Collaborator
ED  - Jamerson, K / Collaborator
ED  - Grimm, R / Collaborator
ED  - Fagan, T / Collaborator
ED  - Bajaj, M / Collaborator
ED  - Katz, L / Collaborator
ED  - Portnay, G / Collaborator
ED  - Altschuller, A / Collaborator
ED  - Desai, V / Collaborator
ED  - Bilazarian, S / Collaborator
ED  - Ipp, E / Collaborator
ED  - Rodelas, R / Collaborator
ED  - Burstein, D / Collaborator
ED  - Berg, J / Collaborator
ED  - Velez, J / Collaborator
ED  - Lund, R / Collaborator
ED  - Rekhi, A / Collaborator
ED  - Martin, E / Collaborator
ED  - Martin, J / Collaborator
ED  - Robertson, D / Collaborator
ED  - Singh, N / Collaborator
ED  - Narayan, P / Collaborator
ED  - Moustafa, M / Collaborator
ED  - Lanier, D / Collaborator
ED  - Seidner, M / Collaborator
ED  - Phillips, A / Collaborator
ED  - Vaughters, B / Collaborator
ED  - Sprague, A / Collaborator
ED  - Swartz, S / Collaborator
ED  - Lopez, R / Collaborator
ED  - Kumar, J / Collaborator
ED  - Bressler, P / Collaborator
ED  - Sadler, L / Collaborator
ED  - Wise, J / Collaborator
ED  - Kilbane, A / Collaborator
ED  - Gerő, László / Collaborator
ED  - Kapocsi, Judit / Collaborator
TI  - Cardiorenal end points in a trial of aliskiren for type 2 diabetes
JF  - NEW ENGLAND JOURNAL OF MEDICINE
J2  - NEW ENGL J MED
VL  - 367
PY  - 2012
IS  - 23
SP  - 2204
EP  - 2213
PG  - 10
SN  - 0028-4793
DO  - 10.1056/NEJMoa1208799
UR  - https://m2.mtmt.hu/api/publication/31337307
ID  - 31337307
AB  - This study was undertaken to determine whether use of the direct renin inhibitor aliskiren would reduce cardiovascular and renal events in patients with type 2 diabetes and chronic kidney disease, cardiovascular disease, or both.In a double-blind fashion, we randomly assigned 8561 patients to aliskiren (300 mg daily) or placebo as an adjunct to an angiotensin-converting-enzyme inhibitor or an angiotensin-receptor blocker. The primary end point was a composite of the time to cardiovascular death or a first occurrence of cardiac arrest with resuscitation; nonfatal myocardial infarction; nonfatal stroke; unplanned hospitalization for heart failure; end-stage renal disease, death attributable to kidney failure, or the need for renal-replacement therapy with no dialysis or transplantation available or initiated; or doubling of the baseline serum creatinine level.The trial was stopped prematurely after the second interim efficacy analysis. After a median follow-up of 32.9 months, the primary end point had occurred in 783 patients (18.3%) assigned to aliskiren as compared with 732 (17.1%) assigned to placebo (hazard ratio, 1.08; 95% confidence interval [CI], 0.98 to 1.20; P=0.12). Effects on secondary renal end points were similar. Systolic and diastolic blood pressures were lower with aliskiren (between-group differences, 1.3 and 0.6 mm Hg, respectively) and the mean reduction in the urinary albumin-to-creatinine ratio was greater (between-group difference, 14 percentage points; 95% CI, 11 to 17). The proportion of patients with hyperkalemia (serum potassium level, ≥6 mmol per liter) was significantly higher in the aliskiren group than in the placebo group (11.2% vs. 7.2%), as was the proportion with reported hypotension (12.1% vs. 8.3%) (P<0.001 for both comparisons).The addition of aliskiren to standard therapy with renin-angiotensin system blockade in patients with type 2 diabetes who are at high risk for cardiovascular and renal events is not supported by these data and may even be harmful. (Funded by Novartis; ALTITUDE ClinicalTrials.gov number, NCT00549757.).
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Lewis, EJ
AU  - Hunsicker, LG
AU  - Clarke, WR
AU  - Berl, T
AU  - Pohl, MA
AU  - Lewis, JB
AU  - Ritz, E
AU  - Atkins, RC
AU  - Rohde, R
AU  - Raz, I
ED  - Nagy, Judit / Collaborator
TI  - Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes.
JF  - NEW ENGLAND JOURNAL OF MEDICINE
J2  - NEW ENGL J MED
VL  - 345
PY  - 2001
IS  - 12
SP  - 851
EP  - 860
PG  - 10
SN  - 0028-4793
DO  - 10.1056/NEJMoa011303
UR  - https://m2.mtmt.hu/api/publication/2979507
ID  - 2979507
N1  - Export Date: 27 January 2024; CODEN: NEJMA
AB  - BACKGROUND: It is unknown whether either the angiotensin-II-receptor blocker irbesartan or the calcium-channel blocker amlodipine slows the progression of nephropathy in patients with type 2 diabetes independently of its capacity to lower the systemic blood pressure. METHODS: We randomly assigned 1715 hypertensive patients with nephropathy due to type 2 diabetes to treatment with irbesartan (300 mg daily), amlodipine (10 mg daily), or placebo. The target blood pressure was 135/85 mm Hg or less in all groups. We compared the groups with regard to the time to the primary composite end point of a doubling of the base-line serum creatinine concentration, the development of end-stage renal disease, or death from any cause. We also compared them with regard to the time to a secondary, cardiovascular composite end point. RESULTS: The mean duration of follow-up was 2.6 years. Treatment with irbesartan was associated with a risk of the primary composite end point that was 20 percent lower than that in the placebo group (P=0.02) and 23 percent lower than that in the amlodipine group (P=0.006). The risk of a doubling of the serum creatinine concentration was 33 percent lower in the irbesartan group than in the placebo group (P=0.003) and 37 percent lower in the irbesartan group than in the amlodipine group (P<0.001). Treatment with irbesartan was associated with a relative risk of end-stage renal disease that was 23 percent lower than that in both other groups (P=0.07 for both comparisons). These differences were not explained by differences in the blood pressures that were achieved. The serum creatinine concentration increased 24 percent more slowly in the irbesartan group than in the placebo group (P=0.008) and 21 percent more slowly than in the amlodipine group (P=0.02). There were no significant differences in the rates of death from any cause or in the cardiovascular composite end point. CONCLUSIONS: The angiotensin-II-receptor blocker irbesartan is effective in protecting against the progression of nephropathy due to type 2 diabetes. This protection is independent of the reduction in blood pressure it causes.
LA  - English
DB  - MTMT
ER  -