@article{MTMT:2708773,
	title = {In Vivo Immunostaining of Hemocyte Compartments in Drosophila for Live Imaging},
	url = {https://m2.mtmt.hu/api/publication/2708773},
	author = {Csordás, Gábor and Varga, Gergely István and Honti, Viktor and Jankovics, Ferenc and Kurucz, Judit Éva and Andó, István},
	doi = {10.1371/journal.pone.0098191},
	journal-iso = {PLOS ONE},
	journal = {PLOS ONE},
	volume = {9},
	unique-id = {2708773},
	issn = {1932-6203},
	abstract = {In recent years, Drosophila melanogaster has become an attractive model organism in which to study the structure and development of the cellular immune components. The emergence of immunological markers greatly accelerated the identification of the immune cells (hemocytes), while the creation of genetic reporter constructs allowed unique insight into the structural organization of hematopoietic tissues. However, investigation of the hemocyte compartments by the means of immunological markers requires dissection and fixation, which regularly disrupt the delicate structure and hamper the microanatomical characterization. Moreover, the investigation of transgenic reporters alone can be misleading as their expression often differs from the native expression pattern of their respective genes. We describe here a method that combines the reporter constructs and the immunological tools in live imaging, thereby allowing use of the array of available immunological markers while retaining the structural integrity of the hematopoietic compartments. The procedure allows the reversible immobilization of Drosophila larvae for high-resolution confocal imaging and the time-lapse video analysis of in vivo reporters. When combined with our antibody injection-based in situ immunostaining assay, the resulting double labeling of the hemocyte compartments can provide new information on the microanatomy and functional properties of the hematopoietic tissues in an intact state. Although this method was developed to study the immune system of Drosophila melanogaster, we anticipate that such a combination of genetic and immunological markers could become a versatile technique for in vivo studies in other biological systems too.},
	year = {2014},
	eissn = {1932-6203},
	orcid-numbers = {Csordás, Gábor/0000-0001-6871-6839; Varga, Gergely István/0000-0001-9073-5788; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:2827923,
	title = {Toward a Comprehensive Map of the Effectors of Rab GTPases},
	url = {https://m2.mtmt.hu/api/publication/2827923},
	author = {Gillingham, Alison K and Sinka, Rita and Torres, Isabel L and Lilley, Kathryn S and Munro, Sean},
	doi = {10.1016/j.devcel.2014.10.007},
	journal-iso = {DEV CELL},
	journal = {DEVELOPMENTAL CELL},
	volume = {31},
	unique-id = {2827923},
	issn = {1534-5807},
	year = {2014},
	eissn = {1878-1551},
	pages = {358-373},
	orcid-numbers = {Sinka, Rita/0000-0003-4040-4184}
}

@article{MTMT:2527687,
	title = {Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila},
	url = {https://m2.mtmt.hu/api/publication/2527687},
	author = {Takáts, Szabolcs and Pircs, Karolina Milena and Nagy, Péter and Varga, Ágnes and Kárpáti, Manuéla and Hegedűs, Krisztina and Kramer, H and Kovács, Attila Lajos and Sass, Miklós and Juhász, Gábor},
	doi = {10.1091/mbc.E13-08-0449},
	journal-iso = {MOL BIOL CELL},
	journal = {MOLECULAR BIOLOGY OF THE CELL},
	volume = {25},
	unique-id = {2527687},
	issn = {1059-1524},
	year = {2014},
	eissn = {1939-4586},
	pages = {1338-1354},
	orcid-numbers = {Takáts, Szabolcs/0000-0003-2139-7740; Pircs, Karolina Milena/0000-0001-8281-4785; Nagy, Péter/0000-0002-5053-0646; Juhász, Gábor/0000-0001-8548-8874}
}

@article{MTMT:2328740,
	title = {Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal function in Drosophila.},
	url = {https://m2.mtmt.hu/api/publication/2328740},
	author = {Takáts, Szabolcs and Nagy, Péter and Varga, Ágnes and Pircs, Karolina Milena and Kárpáti, Manuéla and Varga, Kata and Kovács, Attila Lajos and Hegedűs, Krisztina and Juhász, Gábor},
	doi = {10.1083/jcb.201211160},
	journal-iso = {J CELL BIOL},
	journal = {JOURNAL OF CELL BIOLOGY},
	volume = {201},
	unique-id = {2328740},
	issn = {0021-9525},
	abstract = {During autophagy, phagophores capture portions of cytoplasm and form double-membrane autophagosomes to deliver cargo for lysosomal degradation. How autophagosomes gain competence to fuse with late endosomes and lysosomes is not known. In this paper, we show that Syntaxin17 is recruited to the outer membrane of autophagosomes to mediate fusion through its interactions with ubisnap (SNAP-29) and VAMP7 in Drosophila melanogaster. Loss of these genes results in accumulation of autophagosomes and a block of autolysosomal degradation during basal, starvation-induced, and developmental autophagy. Viable Syntaxin17 mutant adults show large-scale accumulation of autophagosomes in neurons, severe locomotion defects, and premature death. These mutant phenotypes cannot be rescued by neuron-specific inhibition of caspases, suggesting that caspase activation and cell death do not play a major role in brain dysfunction. Our findings reveal the molecular mechanism underlying autophagosomal fusion events and show that lysosomal degradation and recycling of sequestered autophagosome content is crucial to maintain proper functioning of the nervous system.},
	year = {2013},
	eissn = {1540-8140},
	pages = {531-539},
	orcid-numbers = {Takáts, Szabolcs/0000-0003-2139-7740; Nagy, Péter/0000-0002-5053-0646; Pircs, Karolina Milena/0000-0001-8281-4785; Juhász, Gábor/0000-0001-8548-8874}
}

@article{MTMT:1920757,
	title = {Sessile hemocytes as a hematopoietic compartment in drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/1920757},
	author = {Márkus, Róbert and Laurinyecz, Barbara and Kurucz, Judit Éva and Honti, Viktor and Bajusz, Izabella and Sipos, Botond and Somogyi, Kálmán and Kronhamn, J and Hultmark, D and Andó, István},
	doi = {10.1073/pnas.0801766106},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {106},
	unique-id = {1920757},
	issn = {0027-8424},
	year = {2009},
	eissn = {1091-6490},
	pages = {4805-4809},
	orcid-numbers = {Laurinyecz, Barbara/0000-0003-0620-2239; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1915261,
	title = {Definition of Drosophila hemocyte subsets by cell-type specific antigens},
	url = {https://m2.mtmt.hu/api/publication/1915261},
	author = {Kurucz, Judit Éva and Váczi, Balázs and Márkus, Róbert and Laurinyecz, Barbara and Vilmos, Péter and Zsámboki, János and Csorba, Kinga and Gateff, E and Hultmark, D and Andó, István},
	doi = {10.1556/ABiol.58.2007.Suppl.8},
	journal-iso = {ACTA BIOL HUNG},
	journal = {ACTA BIOLOGICA HUNGARICA (1983-2018)},
	volume = {58},
	unique-id = {1915261},
	issn = {0236-5383},
	abstract = {We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. Oil the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmalocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged ill four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocyles.},
	year = {2007},
	eissn = {1588-256X},
	pages = {95-111},
	orcid-numbers = {Laurinyecz, Barbara/0000-0003-0620-2239; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1915010,
	title = {Nimrod, a Putative Phagocytosis Receptor With Egf Repeats in Drosophila Plasmatocytes},
	url = {https://m2.mtmt.hu/api/publication/1915010},
	author = {Kurucz, Judit Éva and Márkus, Róbert and Zsámboki, János and Medzihradszky F., Katalin and Darula, Zsuzsanna and Vilmos, Péter and Udvardy, Andor and Krausz, Ildikó and Lukacsovich, Tamás and Gateff, E and Zettervall, CJ and Hultmark, D and Andó, István},
	doi = {10.1016/j.cub.2007.02.041},
	journal-iso = {CURR BIOL},
	journal = {CURRENT BIOLOGY},
	volume = {17},
	unique-id = {1915010},
	issn = {0960-9822},
	year = {2007},
	eissn = {1879-0445},
	pages = {649-654},
	orcid-numbers = {Andó, István/0000-0002-4648-9396}
}