@article{MTMT:32647429, title = {Exploring the capability of wireless near infrared spectroscopy as a portable seizure detection device for epilepsy patients.}, url = {https://m2.mtmt.hu/api/publication/32647429}, author = {Jeppesen, Jesper and Beniczky, Sándor and Johansen, Peter and Sidenius, Per and Fuglsang-Frederiksen, Anders}, doi = {10.1016/j.seizure.2015.01.015}, journal-iso = {SEIZURE-EUR J EPILEP}, journal = {SEIZURE-EUROPEAN JOURNAL OF EPILEPSY}, volume = {26}, unique-id = {32647429}, issn = {1059-1311}, abstract = {Near infrared spectroscopy (NIRS) has proved useful in measuring significant hemodynamic changes in the brain during epileptic seizures. The advance of NIRS-technology into wireless and portable devices raises the possibility of using the NIRS-technology for portable seizure detection.This study used NIRS to measure changes in oxygenated (HbO), deoxygenated (HbR), and total hemoglobin (HbT) at left and right side of the frontal lobe in 33 patients with epilepsy undergoing long-term video-EEG monitoring. Fifteen patients had 34 focal seizures (20 temporal-, 11 frontal-, 2 parietal-lobe, one unspecific) recorded and analyzed with NIRS. Twelve parameters consisting of maximum increase and decrease changes of HbO, HbR and HbT during seizures (1 min before- to 3 min after seizure-onset) for left and right side, were compared with the patients' own non-seizure periods (a 2-h period and a 30-min exercise-period). In both non-seizure periods 4 min moving windows with maximum overlapping were applied to find non-seizure maxima of the 12 parameters. Detection was defined as positive when seizure maximum change exceeded non-seizure maximum change.When analyzing the 12 parameters separately the positive seizure detection was in the range of 6-24%. The increase in hemodynamics was in general better at detecting seizures (15-24%) than the decrease in hemodynamics (6-18%) (P=0.02).NIRS did not seem to be a suitable technology for generic seizure detection given the device, settings, and methods used in this study. There are still several challenges to overcome before the NIRS-technology can be used as a home-monitoring seizure detection device.}, keywords = {EPILEPSY; Near InfraRed Spectroscopy (NIRS); brain hemodynamics; seizure detection; Portable seizure alarm}, year = {2015}, eissn = {1532-2688}, pages = {43-48} } @article{MTMT:1052898, title = {Transcranial Doppler study of the cerebral hemodynamic changes during breath-holding and hyperventilation tests}, url = {https://m2.mtmt.hu/api/publication/1052898}, author = {Settakis, G and Lengyel, A and Molnár, Csilla and Bereczki, Dániel and Csiba, László and Fülesdi, Béla}, doi = {10.1177/10528402012003007}, journal-iso = {J NEUROIMAGING}, journal = {JOURNAL OF NEUROIMAGING}, volume = {12}, unique-id = {1052898}, issn = {1051-2284}, abstract = {BACKGROUND AND PURPOSE: The aim of the present study was to assess the time course of hyperventilation (HV) and breath-holding (BH) tests in healthy volunteers. SUBJECTS AND METHODS: Young healthy volunteers (n = 29) underwent continuous registration of the middle cerebral artery mean blood flow velocity (MCAV) during and after 30 seconds of BH and 60 seconds of HV. Absolute values as well as percentage changes of the MCAV are reported. In 13 subjects, determination of capillary blood gas parameters (pH, pCO2, pO2, and O2 saturation) was performed before tests, after BH and after HV. RESULTS: MCAV during 30 seconds of breath-holding starts to increase after 10 seconds and reaches its highest level at 30 seconds. After breathing normally, MCAV normalizes within 30 seconds. Hyper-ventilation results in a decrease in MCAV, which reaches a plateau at 20 to 30 seconds after starting to hyperventilate, and blood flow velocity did not change significantly any further until the end of the procedure. The normalization of the MCAV is incomplete at 30 seconds after finishing hyperventilation. None of the capillary blood gases changed significantly after breath-holding, whereas capillary pH, pO2, and oxygen saturation increased and pCO2 decreased after hyperventilation. No relationship was found between capillary blood gas parameters and MCAV values. CONCLUSIONS: The authors concluded that breath-holding and hyperventilation tests seem to be a practical alternative to acetazolamide and the CO2 inhalation method in the assessment of cerebral hemodynamics.}, year = {2002}, eissn = {1552-6569}, pages = {252-258}, orcid-numbers = {Bereczki, Dániel/0000-0002-8374-0500} } @article{MTMT:1772699, title = {SPECT and TCD studies in cluster headache patients}, url = {https://m2.mtmt.hu/api/publication/1772699}, author = {Áfra, Judit and Ertsey, Csaba and Jelencsik, I and Dabasi, Gabriella and Pánczél, Gyula}, journal-iso = {FUNCT NEUROL}, journal = {FUNCTIONAL NEUROLOGY}, volume = {10}, unique-id = {1772699}, issn = {0393-5264}, year = {1995}, eissn = {1971-3274}, pages = {259-264}, orcid-numbers = {Ertsey, Csaba/0000-0003-3288-1941; Dabasi, Gabriella/0000-0002-3484-1049} }