TY - JOUR AU - Munoz, Javier AU - Cortes, Juan Carlos G AU - Sipiczki, Mátyás AU - Ramos, Mariona AU - Angel, Clemente-Ramos Jose AU - Belen, Moreno M AU - Martins, Ivone M AU - Perez, Pilar AU - Carlos, Ribas Juan TI - Extracellular cell wall beta(1,3) glucan is required to couple septation to actomyosin ring contraction JF - JOURNAL OF CELL BIOLOGY J2 - J CELL BIOL VL - 203 PY - 2013 IS - 2 SP - 265 EP - 282 PG - 18 SN - 0021-9525 DO - 10.1083/jcb.201304132 UR - https://m2.mtmt.hu/api/publication/2802051 ID - 2802051 LA - English DB - MTMT ER - TY - JOUR AU - Keresztury, Gábor AU - Holly, Sándor AU - István, Krisztina AU - Sundius, T AU - Lóránd, Tamás TI - Analysis of vibrational spectra of some new E- and Z-4-arylidene-3-isochromanones Part 2. Isomers and conformers of the 2 '-pyrrolyl and 2 '-nitrophenyl derivatives JF - JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS J2 - J BIOCHEM BIOPH METH VL - 61 PY - 2004 IS - 1-2 SP - 107 EP - 118 PG - 12 SN - 0165-022X DO - 10.1016/j.jbbm.2004.04.012 UR - https://m2.mtmt.hu/api/publication/114815 ID - 114815 LA - English DB - MTMT ER - TY - JOUR AU - Lóránd, Tamás AU - Forgó, Péter AU - Foldesi, Andras AU - Osz, Erzsebet AU - Prókai, László TI - Improved solvent-free synthesis and structure elucidation of (E)- and (Z)-4-(arylmethylene)-3-isochromanones JF - EUROPEAN JOURNAL OF ORGANIC CHEMISTRY J2 - EUR J ORG CHEM VL - 2002 ET - 0 PY - 2002 IS - 17 SP - 2996 EP - 3003 PG - 8 SN - 1434-193X DO - 10.1002/1099-0690(200209)2002:17<2996::AID-EJOC2996>3.0.CO;2-G UR - https://m2.mtmt.hu/api/publication/1329710 ID - 1329710 LA - English DB - MTMT ER - TY - JOUR AU - Al-Nakib, TM AU - Lóránd, Tamás AU - Foldesi, A AU - Varghese, R TI - The in vitro antimycotic activity and acute toxicity of third-generation bezylidenetetralones and heteroarylidenetetralones JF - MEDICAL PRINCIPLES AND PRACTICE J2 - MED PRIN PRACT VL - 10 PY - 2001 IS - 4 SP - 191 EP - 196 PG - 6 SN - 1011-7571 DO - 10.1159/000050368 UR - https://m2.mtmt.hu/api/publication/1486611 ID - 1486611 AB - Objectives: A new series of E-2-arylmethylene-1-tetralones and E-2-heteroarylmethylene-1-tetralones (third generation) were designed as potential antimycotic agents against human pathogenic yeasts. Methods: The new compounds were obtained by aldol condensation of 1-tetralone with the appropriately substituted aldehydes in either acid- or base-catalysed conditions. These compounds were tested for their in vitro antimycotic activity against 24 strains of Cryptococcus neoformans, Candida spp. and Trichosporon cutaneum by a microtitre well technique in a liquid casitone medium, using a double dilution method. The toxicity of the new compounds was determined in vitro in cultured HeLa cells, in HeLa growth medium and in vivo in MFI mice. Results: Nineteen new E-2-benzylidine-1-tetralones were prepared, and 16 of the tested compounds showed superior antimycotic activity when compared to the first-generation E-2-benzylidine-1-tetralones synthesised previously. Twelve of these third-generation compounds were more active against different strains of yeasts than 6 commercial antimycotic agents similarly tested. An in vitro toxicity study and an in vivo acute toxicity study in MA mice showed that these compounds were severalfold less toxic than most of the commerical antimycotics, with 4 being comparable to or less toxic than the least toxic of the commercial agents (amphotericin B) tested by the same procedures. Conclusions: Twelve members of this new E-2-benzylidine-1-tetralone class of compounds are promising candidates for antimycotic agents worthy of further investigation. Copyright (C) 2001 S. Karger AG, Basel. LA - English DB - MTMT ER - TY - JOUR AU - Williamson, RT AU - Marquez, BL AU - Gerwick, WH AU - E Kövér, Katalin TI - One- and two-dimensional gradient-selected HSQMBC NMR experiments for the efficient analysis of long-range heteronuclear coupling constants JF - MAGNETIC RESONANCE IN CHEMISTRY J2 - MAGN RESON CHEM VL - 38 PY - 2000 IS - 4 SP - 265 EP - 273 PG - 9 SN - 0749-1581 DO - 10.1002/(SICI)1097-458X(200004)38:4<265::AID-MRC637>3.0.CO;2-# UR - https://m2.mtmt.hu/api/publication/1154229 ID - 1154229 AB - Three new gradient-selected NMR experiments for the analysis of long-range heteronuclear coupling constants are presented. They are demonstrated on a series of compounds including sucrose, strychnine and a complex macrolide, phormidolide, isolated from a marine cyanobacterium. These 1D and 2D heteronuclear single quantum multiple bond correlation (HSQMBC) experiments provide pure absorption, antiphase lineshapes for precise, direct measurement of (n)J(C,H) coupling constants. The example compounds were chosen to demonstrate the high sensitivity and ease of spectral interpretation provided by these HSQMBC experiments. In addition, suppression of one-bond CH correlations has been introduced into the HSQMBC pulse sequence. Copyright (C) 2000 John Wiley & Sons, Ltd. LA - English DB - MTMT ER -