TY - JOUR AU - Fiáth, Richárd AU - Márton, AL AU - Mátyás, Ferenc AU - Pinke, Domonkos Péter AU - Márton, Gergely AU - Tóth, Kinga AU - Ulbert, István TI - Slow insertion of silicon probes improves the quality of acute neuronal recordings JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 9 PY - 2019 IS - 1 PG - 17 SN - 2045-2322 DO - 10.1038/s41598-018-36816-z UR - https://m2.mtmt.hu/api/publication/30322282 ID - 30322282 LA - English DB - MTMT ER - TY - JOUR AU - Fu, TM AU - Hong, GS AU - Zhou, T AU - Schuhmann, TG AU - Viveros, RD AU - Lieber, CM TI - Stable long-term chronic brain mapping at the single-neuron level JF - NATURE METHODS J2 - NAT METHODS VL - 13 PY - 2016 IS - 10 SP - 875 EP - 882 PG - 13 SN - 1548-7091 DO - 10.1038/nmeth.3969 UR - https://m2.mtmt.hu/api/publication/31520373 ID - 31520373 LA - English DB - MTMT ER - TY - JOUR AU - Tóth, Emília AU - Fabó, Dániel AU - Entz, László AU - Ulbert, István AU - Erőss, Loránd TI - Intracranial neuronal ensemble recordings and analysis in epilepsy. JF - JOURNAL OF NEUROSCIENCE METHODS J2 - J NEUROSCI METH VL - 260 PY - 2016 IS - SI SP - 261 EP - 269 PG - 9 SN - 0165-0270 DO - 10.1016/j.jneumeth.2015.09.028 UR - https://m2.mtmt.hu/api/publication/3015678 ID - 3015678 N1 - Funding Agency and Grant Number: Hungarian Government - National Research Development and Innovation Office [OTKA PD101754, KTIA NAP 13-1-2013-0001] Funding text: This work was supported by Hungarian Government - National Research Development and Innovation Office (OTKA PD101754, KTIA NAP 13-1-2013-0001). AB - Pathological neuronal firing was demonstrated 50 years ago as the hallmark of epileptically transformed cortex with the use of implanted microelectrodes. Since then, microelectrodes remained only experimental tools in humans to detect unitary neuronal activity to reveal physiological and pathological brain functions. This recording technique has evolved substantially in the past few decades; however, based on recent human data implying their usefulness as diagnostic tools, we expect a substantial increase in the development of microelectrodes in the near future. Here, we review the technological background and history of microelectrode array development for human examinations in epilepsy, including discussions on of wire-based and microelectrode arrays fabricated using micro-electro-mechanical system (MEMS) techniques and novel future techniques to record neuronal ensemble. We give an overview of clinical and surgical considerations, and try to provide a list of probes on the market with their availability for human recording. Then finally, we briefly review the literature on modulation of single neuron for the treatment of epilepsy, and highlight the current topics under examination that can be background for the future development. LA - English DB - MTMT ER - TY - JOUR AU - Fekete, Zoltán AU - Németh, A AU - Márton, Gergely AU - Ulbert, István AU - Pongrácz, Anita TI - Experimental study on the mechanical interaction between silicon neural microprobes and rat dura mater during insertion JF - JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE J2 - J MATER SCI-MATER M VL - 26 PY - 2015 IS - 2 PG - 9 SN - 0957-4530 DO - 10.1007/s10856-015-5401-y UR - https://m2.mtmt.hu/api/publication/2762232 ID - 2762232 LA - English DB - MTMT ER -