TY  - JOUR
AU  - Antoni, Ferenc András
TI  - Calcium regulation of adenylyl cyclase relevance for endocrine control
JF  - TRENDS IN ENDOCRINOLOGY AND METABOLISM
J2  - TRENDS ENDOCRIN MET
VL  - 8
PY  - 1997
IS  - 1
SP  - 7
EP  - 14
PG  - 8
SN  - 1043-2760
DO  - 10.1016/S1043-2760(96)00206-8
UR  - https://m2.mtmt.hu/api/publication/1776984
ID  - 1776984
AB  - A fundamental process in the hormonal regulation of body functions is the conversion of the intercellular signal into an intracellular signal. The first recognized intracellular messengers mediating the actions of hormones were calcium ions (Ca(2+)) and adenosine 3':5' monophosphate (cAMP), which is synthesized from ATP by adenylyl cyclase. Recent work on the structure of adenylyl cyclases has shown that these enzymes are individually tailored molecular machines controlled by diverse Ca(2+)-dependent mechanisms. These include allosteric regulation of enzyme activity through the Ca(2+)-receptor protein calmodulin, apparently direct actions of Ca(2+)on the cyclase catalytic moiety and phosphorylation/dephosphorylation by Ca(2+)-regulated protein kinases and protein phosphatases. This article is a brief review of the recent developments in the area of cyclase control that forecast a major revival of the interest in cAMP-Ca(2+)interactions. (c) 1997, Elsevier Science Inc. (Trends Endocrinol Metab 1997;8:7-14).
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Kiss, István
AU  - BEATON, AH
AU  - TARDIFF, J
AU  - FRISTROM, D
AU  - FRISTROM, JW
TI  - Interactions and developmental effects of mutations at the 2B5 locus of Drosophila melanogaster.
JF  - GENETICS
J2  - GENETICS
VL  - 118
PY  - 1988
SP  - 247
EP  - 259
PG  - 13
SN  - 0016-6731
UR  - https://m2.mtmt.hu/api/publication/1904570
ID  - 1904570
LA  - English
DB  - MTMT
ER  -