@article{MTMT:3096913,
	title = {Transdifferentiation and Proliferation in Two Distinct Hemocyte Lineages in Drosophila melanogaster Larvae after Wasp Infection.},
	url = {https://m2.mtmt.hu/api/publication/3096913},
	author = {Anderl, I and Vesala, L and Ihalainen, TO and Vanha-Aho, LM and Andó, István and Ramet, M and Hultmark, D},
	doi = {10.1371/journal.ppat.1005746},
	journal-iso = {PLOS PATHOG},
	journal = {PLOS PATHOGENS},
	volume = {12},
	unique-id = {3096913},
	issn = {1553-7366},
	abstract = {Cellular immune responses require the generation and recruitment of diverse blood cell types that recognize and kill pathogens. In Drosophila melanogaster larvae, immune-inducible lamellocytes participate in recognizing and killing parasitoid wasp eggs. However, the sequence of events required for lamellocyte generation remains controversial. To study the cellular immune system, we developed a flow cytometry approach using in vivo reporters for lamellocytes as well as for plasmatocytes, the main hemocyte type in healthy larvae. We found that two different blood cell lineages, the plasmatocyte and lamellocyte lineages, contribute to the generation of lamellocytes in a demand-adapted hematopoietic process. Plasmatocytes transdifferentiate into lamellocyte-like cells in situ directly on the wasp egg. In parallel, a novel population of infection-induced cells, which we named lamelloblasts, appears in the circulation. Lamelloblasts proliferate vigorously and develop into the major class of circulating lamellocytes. Our data indicate that lamellocyte differentiation upon wasp parasitism is a plastic and dynamic process. Flow cytometry with in vivo hemocyte reporters can be used to study this phenomenon in detail.},
	year = {2016},
	eissn = {1553-7374},
	pages = {e1005746},
	orcid-numbers = {Andó, István/0000-0002-4648-9396}
}

@article{MTMT:2853633,
	title = {The Nimrod transmembrane receptor Eater is required for hemocyte attachment to the sessile compartment in Drosophila melanogaster.},
	url = {https://m2.mtmt.hu/api/publication/2853633},
	author = {Bretscher, AJ and Honti, Viktor and Binggeli, O and Burri, O and Poidevin, M and Kurucz, Judit Éva and Zsámboki, János and Andó, István and Lemaitre, B},
	doi = {10.1242/bio.201410595},
	journal-iso = {BIOL OPEN},
	journal = {BIOLOGY OPEN},
	volume = {4},
	unique-id = {2853633},
	issn = {2046-6390},
	abstract = {Eater is an EGF-like repeat transmembrane receptor of the Nimrod family and is expressed in Drosophila hemocytes. Eater was initially identified for its role in phagocytosis of both Gram-positive and Gram-negative bacteria. We have deleted eater and show that it appears to be required for efficient phagocytosis of Gram-positive but not Gram-negative bacteria. However, the most striking phenotype of eater deficient larvae is the near absence of sessile hemocytes, both plasmatocyte and crystal cell types. The eater deletion is the first loss of function mutation identified that causes absence of the sessile hemocyte state. Our study shows that Eater is required cell-autonomously in plasmatocytes for sessility. However, the presence of crystal cells in the sessile compartment requires Eater in plasmatocytes. We also show that eater deficient hemocytes exhibit a cell adhesion defect. Collectively, our data uncovers a new requirement of Eater in enabling hemocyte attachment at the sessile compartment and points to a possible role of Nimrod family members in hemocyte adhesion.},
	year = {2015},
	eissn = {2046-6390},
	pages = {355-363},
	orcid-numbers = {Andó, István/0000-0002-4648-9396}
}

@article{MTMT:2372553,
	title = {The cell-mediated immunity of Drosophila melanogaster: Hemocyte lineages, immune compartments, microanatomy and regulation.},
	url = {https://m2.mtmt.hu/api/publication/2372553},
	author = {Honti, Viktor and Csordás, Gábor and Kurucz, Judit Éva and Márkus, Róbert and Andó, István},
	doi = {10.1016/j.dci.2013.06.005},
	journal-iso = {DEV COMP IMMUNOL},
	journal = {DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY},
	volume = {42},
	unique-id = {2372553},
	issn = {0145-305X},
	abstract = {In the animal kingdom, innate immunity is the first line of defense against invading pathogens. The dangers of microbial and parasitic attacks are countered by similar mechanisms, involving the prototypes of the cell-mediated immune responses, the phagocytosis and encapsulation. Work on Drosophila has played an important role in promoting an understanding of the basic mechanisms of phylogenetically conserved modules of innate immunity. The aim of this review is to survey the developments in the identification and functional definition of immune cell types and the immunological compartments of Drosophila melanogaster. We focus on the molecular and developmental aspects of the blood cell types and compartments, as well as the dynamics of blood cell development and the immune response. Further advances in the characterization of the innate immune mechanisms in Drosophila will provide basic clues to the understanding of the importance of the evolutionary conserved mechanisms of innate immune defenses in the animal kingdom.},
	year = {2014},
	eissn = {1879-0089},
	pages = {47-56},
	orcid-numbers = {Csordás, Gábor/0000-0001-6871-6839; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1921048,
	title = {Cell lineage tracing reveals the plasticity of the hemocyte lineages and of the hematopoietic compartments in drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/1921048},
	author = {Honti, Viktor and Csordás, Gábor and Márkus, Róbert and Kurucz, Judit Éva and Jankovics, Ferenc and Andó, István},
	doi = {10.1016/j.molimm.2010.04.017},
	journal-iso = {MOL IMMUNOL},
	journal = {MOLECULAR IMMUNOLOGY},
	volume = {47},
	unique-id = {1921048},
	issn = {0161-5890},
	keywords = {Animals; Immunity, Innate; Immunity, Cellular; Receptors, Scavenger/genetics; Hemocytes/cytology/*physiology; *Hematopoiesis; Drosophila melanogaster/embryology/*immunology; Drosophila Proteins/genetics; *Cell Lineage},
	year = {2010},
	eissn = {1872-9142},
	pages = {1997-2004},
	orcid-numbers = {Csordás, Gábor/0000-0001-6871-6839; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1920812,
	title = {In vivo detection of lamellocytes in Drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/1920812},
	author = {Honti, Viktor and Kurucz, Judit Éva and Csordás, Gábor and Laurinyecz, Barbara and Márkus, Róbert and Andó, István},
	doi = {10.1016/j.imlet.2009.08.004},
	journal-iso = {IMMUNOL LETT},
	journal = {IMMUNOLOGY LETTERS},
	volume = {126},
	unique-id = {1920812},
	issn = {0165-2478},
	keywords = {Animals; Cell Differentiation; Mutagenesis, Insertional; Fluorescent Antibody Technique, Indirect; Green Fluorescent Proteins/genetics/metabolism; DNA Transposable Elements/genetics; Larva/genetics/metabolism; Hemocytes/cytology/*metabolism; Drosophila melanogaster/*genetics/metabolism; Drosophila Proteins/*genetics},
	year = {2009},
	eissn = {1879-0542},
	pages = {83-84},
	orcid-numbers = {Csordás, Gábor/0000-0001-6871-6839; Laurinyecz, Barbara/0000-0003-0620-2239; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1920757,
	title = {Sessile hemocytes as a hematopoietic compartment in drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/1920757},
	author = {Márkus, Róbert and Laurinyecz, Barbara and Kurucz, Judit Éva and Honti, Viktor and Bajusz, Izabella and Sipos, Botond and Somogyi, Kálmán and Kronhamn, J and Hultmark, D and Andó, István},
	doi = {10.1073/pnas.0801766106},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {106},
	unique-id = {1920757},
	issn = {0027-8424},
	year = {2009},
	eissn = {1091-6490},
	pages = {4805-4809},
	orcid-numbers = {Laurinyecz, Barbara/0000-0003-0620-2239; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1915261,
	title = {Definition of Drosophila hemocyte subsets by cell-type specific antigens},
	url = {https://m2.mtmt.hu/api/publication/1915261},
	author = {Kurucz, Judit Éva and Váczi, Balázs and Márkus, Róbert and Laurinyecz, Barbara and Vilmos, Péter and Zsámboki, János and Csorba, Kinga and Gateff, E and Hultmark, D and Andó, István},
	doi = {10.1556/ABiol.58.2007.Suppl.8},
	journal-iso = {ACTA BIOL HUNG},
	journal = {ACTA BIOLOGICA HUNGARICA (1983-2018)},
	volume = {58},
	unique-id = {1915261},
	issn = {0236-5383},
	abstract = {We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. Oil the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmalocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged ill four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocyles.},
	year = {2007},
	eissn = {1588-256X},
	pages = {95-111},
	orcid-numbers = {Laurinyecz, Barbara/0000-0003-0620-2239; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1915010,
	title = {Nimrod, a Putative Phagocytosis Receptor With Egf Repeats in Drosophila Plasmatocytes},
	url = {https://m2.mtmt.hu/api/publication/1915010},
	author = {Kurucz, Judit Éva and Márkus, Róbert and Zsámboki, János and Medzihradszky F., Katalin and Darula, Zsuzsanna and Vilmos, Péter and Udvardy, Andor and Krausz, Ildikó and Lukacsovich, Tamás and Gateff, E and Zettervall, CJ and Hultmark, D and Andó, István},
	doi = {10.1016/j.cub.2007.02.041},
	journal-iso = {CURR BIOL},
	journal = {CURRENT BIOLOGY},
	volume = {17},
	unique-id = {1915010},
	issn = {0960-9822},
	year = {2007},
	eissn = {1879-0445},
	pages = {649-654},
	orcid-numbers = {Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1912851,
	title = {Hemese, a hemocyte-specific transmembrane protein, affects the cellular immune response in Drosophila},
	url = {https://m2.mtmt.hu/api/publication/1912851},
	author = {Kurucz, Judit Éva and Zettervall, CJ and Sinka, Rita and Vilmos, Péter and Pivarcsi, A and Ekengren, S and Hegedűs, Zoltán and Andó, István and Hultmark, D},
	doi = {10.1073/pnas.0436940100},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {100},
	unique-id = {1912851},
	issn = {0027-8424},
	year = {2003},
	eissn = {1091-6490},
	pages = {2622-2627},
	orcid-numbers = {Sinka, Rita/0000-0003-4040-4184; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1912067,
	title = {An interaction type of genetic screen reveals a role of the Rab11 gene in oskar mRNA localization in the developing Drosophila melanogaster oocyte},
	url = {https://m2.mtmt.hu/api/publication/1912067},
	author = {Jankovics, Ferenc and Sinka, Rita and Erdélyi, Miklós},
	doi = {10.1093/genetics/158.3.1177},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {158},
	unique-id = {1912067},
	issn = {0016-6731},
	year = {2001},
	eissn = {1943-2631},
	pages = {1177-1188},
	orcid-numbers = {Sinka, Rita/0000-0003-4040-4184}
}