TY  - JOUR
AU  - Honti, Viktor
AU  - Csordás, Gábor
AU  - Kurucz, Judit Éva
AU  - Márkus, Róbert
AU  - Andó, István
TI  - The cell-mediated immunity of Drosophila melanogaster: Hemocyte lineages, immune compartments, microanatomy and regulation.
JF  - DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
J2  - DEV COMP IMMUNOL
VL  - 42
PY  - 2014
IS  - 1
SP  - 47
EP  - 56
PG  - 10
SN  - 0145-305X
DO  - 10.1016/j.dci.2013.06.005
UR  - https://m2.mtmt.hu/api/publication/2372553
ID  - 2372553
N1  - Cited By :124            
            Export Date: 19 January 2022            
            CODEN: DCIMD            
            Correspondence Address: Andó, I.; Institute of Genetics Biological Research Centre of the Hungarian Academy of Sciences, P.O. Box 521, Szeged H-6701, Hungary; email: ando.istvan@brc.mta.hu
AB  - In the animal kingdom, innate immunity is the first line of defense against invading pathogens. The dangers of microbial and parasitic attacks are countered by similar mechanisms, involving the prototypes of the cell-mediated immune responses, the phagocytosis and encapsulation. Work on Drosophila has played an important role in promoting an understanding of the basic mechanisms of phylogenetically conserved modules of innate immunity. The aim of this review is to survey the developments in the identification and functional definition of immune cell types and the immunological compartments of Drosophila melanogaster. We focus on the molecular and developmental aspects of the blood cell types and compartments, as well as the dynamics of blood cell development and the immune response. Further advances in the characterization of the innate immune mechanisms in Drosophila will provide basic clues to the understanding of the importance of the evolutionary conserved mechanisms of innate immune defenses in the animal kingdom.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Honti, Viktor
AU  - Csordás, Gábor
AU  - Márkus, Róbert
AU  - Kurucz, Judit Éva
AU  - Jankovics, Ferenc
AU  - Andó, István
TI  - Cell lineage tracing reveals the plasticity of the hemocyte lineages and of the hematopoietic compartments in drosophila melanogaster
JF  - MOLECULAR IMMUNOLOGY
J2  - MOL IMMUNOL
VL  - 47
PY  - 2010
IS  - 11-12
SP  - 1997
EP  - 2004
PG  - 8
SN  - 0161-5890
DO  - 10.1016/j.molimm.2010.04.017
UR  - https://m2.mtmt.hu/api/publication/1921048
ID  - 1921048
N1  - Cited By :83            
            Export Date: 19 January 2022            
            CODEN: IMCHA            
            Correspondence Address: Andó, I.; Institute of Genetics, Temesvári krt. 62, 6726 Szeged, Csongrád, Hungary; email: ando@brc.hu
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Márkus, Róbert
AU  - Laurinyecz, Barbara
AU  - Kurucz, Judit Éva
AU  - Honti, Viktor
AU  - Bajusz, Izabella
AU  - Sipos, Botond
AU  - Somogyi, Kálmán
AU  - Kronhamn, J
AU  - Hultmark, D
AU  - Andó, István
TI  - Sessile hemocytes as a hematopoietic compartment in drosophila melanogaster
JF  - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
J2  - P NATL ACAD SCI USA
VL  - 106
PY  - 2009
IS  - 12
SP  - 4805
EP  - 4809
PG  - 5
SN  - 0027-8424
DO  - 10.1073/pnas.0801766106
UR  - https://m2.mtmt.hu/api/publication/1920757
ID  - 1920757
N1  - Cited By :174            
            Export Date: 30 June 2022            
            CODEN: PNASA
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Kurucz, Judit Éva
AU  - Váczi, Balázs
AU  - Márkus, Róbert
AU  - Laurinyecz, Barbara
AU  - Vilmos, Péter
AU  - Zsámboki, János
AU  - Csorba, Kinga
AU  - Gateff, E
AU  - Hultmark, D
AU  - Andó, István
TI  - Definition of Drosophila hemocyte subsets by cell-type specific antigens
JF  - ACTA BIOLOGICA HUNGARICA (1983-2018)
J2  - ACTA BIOL HUNG
VL  - 58
PY  - 2007
IS  - Suppl. 1
SP  - 95
EP  - 111
PG  - 17
SN  - 0236-5383
DO  - 10.1556/ABiol.58.2007.Suppl.8
UR  - https://m2.mtmt.hu/api/publication/1915261
ID  - 1915261
AB  - We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. Oil the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmalocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged ill four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocyles.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Márkus, Róbert
AU  - Kurucz, Judit Éva
AU  - Rus, Florentina
AU  - Andó, István
TI  - Sterile wounding is a minimal and sufficient trigger for a cellular immune response in Drosophila melanogaster
JF  - IMMUNOLOGY LETTERS
J2  - IMMUNOL LETT
VL  - 101
PY  - 2005
IS  - 1
SP  - 108
EP  - 111
PG  - 4
SN  - 0165-2478
DO  - 10.1016/j.imlet.2005.03.021
UR  - https://m2.mtmt.hu/api/publication/1913892
ID  - 1913892
LA  - English
DB  - MTMT
ER  -