{ "labelLang" : "eng", "responseDate" : "2024-03-28 23:44", "paging" : { "last" : true, "first" : true, "totalPages" : 1, "totalElements" : 10, "totalUncutElements" : 10, "totalEstimatedElements" : 1, "size" : 100, "number" : 1, "numberOfElements" : 10, "sort" : [ { "direction" : "DESC", "property" : "publishedYear", "ascending" : false }, { "direction" : "ASC", "property" : "firstAuthor", "ascending" : true }, { "direction" : "ASC", "property" : "title", "ascending" : true } ] }, "content" : [ { "otype" : "JournalArticle", "mtid" : 3378998, "status" : "VALIDATED", "published" : true, "comment" : "Megosztott első szerzőség. These authors contributed equally to this work: Viktória Lázár and Ana Martins.", "unhandledTickets" : 0, "oldTimestamp" : "2018-07-12T22:20:08.000+0000", "deleted" : false, "oldId" : 3378998, "lastRefresh" : "2024-03-25T07:58:08.762+0000", "lastModified" : "2021-11-12T20:23:55.473+0000", "created" : "2018-05-08T12:58:58.000+0000", "creator" : { "otype" : "Admin", "mtid" : 10018677, "link" : "/api/admin/10018677", "label" : "Kata Berkes (SZBK 5admin)", "familyName" : "Berkes", "givenName" : "Kata", "published" : true, "oldId" : 10018677, "snippet" : true }, "lastDuplumOK" : "2024-01-16T12:48:19.508+0000", "lastDuplumSearch" : "2024-01-16T12:48:19.508+0000", "validated" : "2021-11-12T20:23:55.488+0000", "validator" : { "otype" : "Admin", "mtid" : 10003132, "link" : "/api/admin/10003132", "label" : "András Balázs (MTMT Központ, admin)", "familyName" : "Balázs", "givenName" : "András", "published" : true, "oldId" : 10003132, "snippet" : true }, "tempLockers" : [ { "otype" : "Admin", "mtid" : 10003141, "link" : "/api/admin/10003141", "label" : "Zsuzsa Aggod (MTMT 2-3, admin)", "familyName" : "Aggod", "givenName" : "Zsuzsa", "published" : true, "oldId" : 10003141, "snippet" : true } ], "tempLocked" : "2021-12-22T06:55:58.897+0000", "core" : true, "citation" : true, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Journal Article", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "subType" : { "otype" : "SubType", "mtid" : 10000059, "link" : "/api/subtype/10000059", "label" : "Article (Journal Article)", "name" : "Szakcikk", "nameEng" : "Article", "docType" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Journal Article", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "listPosition" : 101, "published" : true, "oldId" : 10000059, "snippet" : true }, "category" : { "otype" : "Category", "mtid" : 1, "link" : "/api/category/1", "label" : "Scientific", "published" : true, "oldId" : 1, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10002, "link" : "/api/language/10002", "label" : "English", "name" : "Angol", "nameEng" : "English", "published" : true, "oldId" : 2, "snippet" : true } ], "firstAuthor" : "Lazar, V", "authorships" : [ { "otype" : "PersonAuthorship", "mtid" : 10149270, "link" : "/api/authorship/10149270", "label" : "Lazar, V [Lázár, Viktória (Molekuláris biológia), author] Institute of Biochemistry", "listPosition" : 1, "share" : 0.04, "first" : true, "last" : false, "author" : { "otype" : "Author", "mtid" : 10036222, "link" : "/api/author/10036222", "label" : "Viktória Lázár (Molekuláris biológia)", "familyName" : "Lázár", "givenName" : "Viktória", "published" : true, "oldId" : 10036222, "snippet" : true }, "familyName" : "Lazar", "givenName" : "V", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329329, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149271, "link" : "/api/authorship/10149271", "label" : "Martins, A* [Martins, Ana (mikrobiológia), author] Institute of Biochemistry", "listPosition" : 2, "share" : 0.04, "first" : true, "last" : false, "author" : { "otype" : "Author", "mtid" : 10028887, "link" : "/api/author/10028887", "label" : "Ana Martins (mikrobiológia)", "familyName" : "Martins", "givenName" : "Ana", "published" : true, "oldId" : 10028887, "snippet" : true }, "familyName" : "Martins", "givenName" : "A", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329328, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149272, "link" : "/api/authorship/10149272", "label" : "Spohn, R [Spohn, Réka (Biokémia), author] Institute of Biochemistry", "listPosition" : 3, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10039902, "link" : "/api/author/10039902", "label" : "Réka Spohn (Biokémia)", "familyName" : "Spohn", "givenName" : "Réka", "published" : true, "oldId" : 10039902, "snippet" : true }, "familyName" : "Spohn", "givenName" : "R", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329327, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149273, "link" : "/api/authorship/10149273", "label" : "Daruka, L [Daruka, Lejla (biokémia), author] Institute of Biochemistry", "listPosition" : 4, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10061519, "link" : "/api/author/10061519", "label" : "Lejla Daruka (biokémia)", "familyName" : "Daruka", "givenName" : "Lejla", "published" : true, "oldId" : 10061519, "snippet" : true }, "familyName" : "Daruka", "givenName" : "L", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329326, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149274, "link" : "/api/authorship/10149274", "label" : "Grezal, G [Grézal, Gábor (molekuláris biológia), author] Institute of Biochemistry", "listPosition" : 5, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10031498, "link" : "/api/author/10031498", "label" : "Gábor Grézal (molekuláris biológia)", "familyName" : "Grézal", "givenName" : "Gábor", "published" : true, "oldId" : 10031498, "snippet" : true }, "familyName" : "Grezal", "givenName" : "G", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329325, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149275, "link" : "/api/authorship/10149275", "label" : "Fekete, G [Fekete, Gergely (biokémia), author] Institute of Biochemistry", "listPosition" : 6, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10033116, "link" : "/api/author/10033116", "label" : "Gergely Fekete (biokémia)", "familyName" : "Fekete", "givenName" : "Gergely", "published" : true, "oldId" : 10033116, "snippet" : true }, "familyName" : "Fekete", "givenName" : "G", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329324, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149276, "link" : "/api/authorship/10149276", "label" : "Szamel, M [Számel, Mónika (biokémia), author] Institute of Biochemistry", "listPosition" : 7, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10061522, "link" : "/api/author/10061522", "label" : "Mónika Számel (biokémia)", "familyName" : "Számel", "givenName" : "Mónika", "published" : true, "oldId" : 10061522, "snippet" : true }, "familyName" : "Szamel", "givenName" : "M", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329323, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149277, "link" : "/api/authorship/10149277", "label" : "Jangir, PK [Jangir, Pramod Kumar (biokémia), author] Institute of Biochemistry", "listPosition" : 8, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10060960, "link" : "/api/author/10060960", "label" : "Pramod Kumar Jangir (biokémia)", "familyName" : "Jangir", "givenName" : "Pramod Kumar", "published" : true, "oldId" : 10060960, "snippet" : true }, "familyName" : "Jangir", "givenName" : "PK", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329322, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149278, "link" : "/api/authorship/10149278", "label" : "Kintses, B [Kintses, Bálint (biokémia), author] Institute of Biochemistry", "listPosition" : 9, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10045675, "link" : "/api/author/10045675", "label" : "Bálint Kintses (biokémia)", "familyName" : "Kintses", "givenName" : "Bálint", "published" : true, "oldId" : 10045675, "snippet" : true }, "familyName" : "Kintses", "givenName" : "B", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329321, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149279, "link" : "/api/authorship/10149279", "label" : "Csorgo, B [Csörgő, Bálint (Biológus), author] Institute of Biochemistry", "listPosition" : 10, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10024944, "link" : "/api/author/10024944", "label" : "Bálint Csörgő (Biológus)", "familyName" : "Csörgő", "givenName" : "Bálint", "published" : true, "oldId" : 10024944, "snippet" : true }, "familyName" : "Csorgo", "givenName" : "B", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329320, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149280, "link" : "/api/authorship/10149280", "label" : "Nyerges, A [Nyerges, Ákos (biokémia), author] Institute of Biochemistry", "listPosition" : 11, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10043320, "link" : "/api/author/10043320", "label" : "Ákos Nyerges (biokémia)", "familyName" : "Nyerges", "givenName" : "Ákos", "published" : true, "oldId" : 10043320, "snippet" : true }, "familyName" : "Nyerges", "givenName" : "A", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329319, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149281, "link" : "/api/authorship/10149281", "label" : "Gyorkei, A [Györkei, Ádám (biokémia), author] Institute of Biochemistry", "listPosition" : 12, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10045634, "link" : "/api/author/10045634", "label" : "Ádám Györkei (biokémia)", "familyName" : "Györkei", "givenName" : "Ádám", "published" : true, "oldId" : 10045634, "snippet" : true }, "familyName" : "Gyorkei", "givenName" : "A", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329318, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149282, "link" : "/api/authorship/10149282", "label" : "Kincses, A [Kincses, András (biofizika), author] Institute of Biophysics", "listPosition" : 13, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10032015, "link" : "/api/author/10032015", "label" : "András Kincses (biofizika)", "familyName" : "Kincses", "givenName" : "András", "published" : true, "oldId" : 10032015, "snippet" : true }, "familyName" : "Kincses", "givenName" : "A", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329317, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149283, "link" : "/api/authorship/10149283", "label" : "Der, A [Dér, András (Biofizika), author] Institute of Biophysics", "listPosition" : 14, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10009032, "link" : "/api/author/10009032", "label" : "András Dér (Biofizika)", "familyName" : "Dér", "givenName" : "András", "published" : true, "oldId" : 10009032, "snippet" : true }, "familyName" : "Der", "givenName" : "A", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329316, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149284, "link" : "/api/authorship/10149284", "label" : "Walter, FR [Walter, Fruzsina (biofizika), author] Institute of Biophysics", "listPosition" : 15, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10032624, "link" : "/api/author/10032624", "label" : "Fruzsina Walter (biofizika)", "familyName" : "Walter", "givenName" : "Fruzsina", "published" : true, "oldId" : 10032624, "snippet" : true }, "familyName" : "Walter", "givenName" : "FR", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329315, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149285, "link" : "/api/authorship/10149285", "label" : "Deli, MA [Deli, Mária Anna (Neurobiológia, vé...), author] Institute of Biophysics", "listPosition" : 16, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10008996, "link" : "/api/author/10008996", "label" : "Mária Anna Deli (Neurobiológia, vér-agy gát)", "familyName" : "Deli", "givenName" : "Mária Anna", "published" : true, "oldId" : 10008996, "snippet" : true }, "familyName" : "Deli", "givenName" : "MA", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329314, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149286, "link" : "/api/authorship/10149286", "label" : "Urban, E [Zsoldiné Urbán, Edit (Orvostudomány), author] Department of Clinical Microbiology (SZTE / ÁOK)", "listPosition" : 17, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10027939, "link" : "/api/author/10027939", "label" : "Edit Zsoldiné Urbán (Orvostudomány)", "familyName" : "Zsoldiné Urbán", "givenName" : "Edit", "published" : true, "oldId" : 10027939, "snippet" : true }, "familyName" : "Urban", "givenName" : "E", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329313, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149287, "link" : "/api/authorship/10149287", "label" : "Hegedus, Z [Hegedüs, Zsófia (gyógyszerkémia), author] Department of Pharmaceutical Analytics (SZTE / FP)", "listPosition" : 18, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10043382, "link" : "/api/author/10043382", "label" : "Zsófia Hegedüs (gyógyszerkémia)", "familyName" : "Hegedüs", "givenName" : "Zsófia", "published" : true, "oldId" : 10043382, "snippet" : true }, "familyName" : "Hegedus", "givenName" : "Z", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329312, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149288, "link" : "/api/authorship/10149288", "label" : "Olajos, G [Olajos, Gábor (Gyógyszerkémia), author] Department of Pharmaceutical Analytics (SZTE / FP)", "listPosition" : 19, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10033721, "link" : "/api/author/10033721", "label" : "Gábor Olajos (Gyógyszerkémia)", "familyName" : "Olajos", "givenName" : "Gábor", "published" : true, "oldId" : 10033721, "snippet" : true }, "familyName" : "Olajos", "givenName" : "G", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329311, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149289, "link" : "/api/authorship/10149289", "label" : "Mehi, O [Méhi, Orsolya Katinka (biokémia), author] Institute of Biochemistry", "listPosition" : 20, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10033114, "link" : "/api/author/10033114", "label" : "Orsolya Katinka Méhi (biokémia)", "familyName" : "Méhi", "givenName" : "Orsolya Katinka", "published" : true, "oldId" : 10033114, "snippet" : true }, "familyName" : "Mehi", "givenName" : "O", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329310, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149290, "link" : "/api/authorship/10149290", "label" : "Balint, B [Bálint, Balázs (biológia, bioinfo...), author]", "listPosition" : 21, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10024896, "link" : "/api/author/10024896", "label" : "Balázs Bálint (biológia, bioinformatika)", "familyName" : "Bálint", "givenName" : "Balázs", "published" : true, "oldId" : 10024896, "snippet" : true }, "familyName" : "Balint", "givenName" : "B", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329309, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149291, "link" : "/api/authorship/10149291", "label" : "Nagy, I [Nagy, István (Genomika, immunol...), author] Institute of Biochemistry", "listPosition" : 22, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10026761, "link" : "/api/author/10026761", "label" : "István Nagy (Genomika, immunológia)", "familyName" : "Nagy", "givenName" : "István", "published" : true, "oldId" : 10026761, "snippet" : true }, "familyName" : "Nagy", "givenName" : "I", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329308, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149292, "link" : "/api/authorship/10149292", "label" : "Martinek, TA [Martinek, Tamás (Gyógyszerkémia), author] Department of Pharmaceutical Analytics (SZTE / FP)", "listPosition" : 23, "share" : 0.04, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10001168, "link" : "/api/author/10001168", "label" : "Tamás Martinek (Gyógyszerkémia)", "familyName" : "Martinek", "givenName" : "Tamás", "published" : true, "oldId" : 10001168, "snippet" : true }, "familyName" : "Martinek", "givenName" : "TA", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329307, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149293, "link" : "/api/authorship/10149293", "label" : "Papp, B ✉ [Papp, Balázs (biokémia), author] Institute of Biochemistry", "listPosition" : 24, "share" : 0.04, "first" : false, "last" : false, "corresponding" : true, "author" : { "otype" : "Author", "mtid" : 10025198, "link" : "/api/author/10025198", "label" : "Balázs Papp (biokémia)", "familyName" : "Papp", "givenName" : "Balázs", "published" : true, "oldId" : 10025198, "snippet" : true }, "familyName" : "Papp", "givenName" : "B", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329306, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10149294, "link" : "/api/authorship/10149294", "label" : "Pal, C ✉ [Pál, Csaba (biokémia), author] Institute of Biochemistry", "listPosition" : 25, "share" : 0.04, "first" : false, "last" : true, "corresponding" : true, "author" : { "otype" : "Author", "mtid" : 10027825, "link" : "/api/author/10027825", "label" : "Csaba Pál (biokémia)", "familyName" : "Pál", "givenName" : "Csaba", "published" : true, "oldId" : 10027825, "snippet" : true }, "familyName" : "Pal", "givenName" : "C", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Author", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 28329305, "snippet" : true } ], "title" : "Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 1301941, "link" : "/api/publicationidentifier/1301941", "label" : "DOI: 10.1038/s41564-018-0164-0", "source" : { "otype" : "PlainSource", "mtid" : 6, "link" : "/api/publicationsource/6", "label" : "DOI", "type" : { "otype" : "PublicationSourceType", "mtid" : 10001, "link" : "/api/publicationsourcetype/10001", "label" : "DOI", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "DOI", "nameEng" : "DOI", "linkPattern" : "https://doi.org/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 6, "snippet" : true }, "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "10.1038/s41564-018-0164-0", "realUrl" : "https://doi.org/10.1038/s41564-018-0164-0", "published" : false, "oldId" : 1781736, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 1301943, "link" : "/api/publicationidentifier/1301943", "label" : "REAL: 80252", "source" : { "otype" : "SwordSource", "mtid" : 36, "link" : "/api/publicationsource/36", "label" : "REAL", "type" : { "otype" : "PublicationSourceType", "mtid" : 10007, "link" : "/api/publicationsourcetype/10007", "label" : "Repozitórium", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "REAL", "nameEng" : "REAL", "linkPattern" : "http://real.mtak.hu/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 36, "snippet" : true }, "oaType" : "RESTRICTED", "oaFree" : false, "validState" : "NO", "idValue" : "80252", "realUrl" : "http://real.mtak.hu/80252", "published" : false, "oldId" : 1782284, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 1301939, "link" : "/api/publicationidentifier/1301939", "label" : "WoS: 000433302800014", "source" : { "otype" : "PlainSource", "mtid" : 1, "link" : "/api/publicationsource/1", "label" : "WoS", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "WoS", "nameEng" : "WoS", "linkPattern" : "https://www.webofscience.com/wos/woscc/full-record/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 1, "snippet" : true }, "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "000433302800014", "realUrl" : "https://www.webofscience.com/wos/woscc/full-record/000433302800014", "published" : false, "oldId" : 1790588, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 1301940, "link" : "/api/publicationidentifier/1301940", "label" : "Scopus: 85047785075", "source" : { "otype" : "PlainSource", "mtid" : 3, "link" : "/api/publicationsource/3", "label" : "Scopus", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "Scopus", "linkPattern" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@", "publiclyVisible" : true, "published" : true, "oldId" : 3, "snippet" : true }, "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "85047785075", "realUrl" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85047785075", "published" : false, "oldId" : 1787435, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 1301942, "link" : "/api/publicationidentifier/1301942", "label" : "PubMed: 29795541", "source" : { "otype" : "PlainSource", "mtid" : 17, "link" : "/api/publicationsource/17", "label" : "PubMed", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "PubMed", "nameEng" : "PubMed", "linkPattern" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract", "publiclyVisible" : true, "published" : true, "oldId" : 17, "snippet" : true }, "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "29795541", "realUrl" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=29795541&dopt=Abstract", "published" : false, "oldId" : 1781737, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 15871931, "link" : "/api/publicationidentifier/15871931", "label" : "Pubmed Central: PMC6544545", "source" : { "otype" : "PlainSource", "mtid" : 137, "link" : "/api/publicationsource/137", "label" : "Pubmed Central", "type" : { "otype" : "PublicationSourceType", "mtid" : 10007, "link" : "/api/publicationsourcetype/10007", "label" : "Repozitórium", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "Pubmed Central", "linkPattern" : "http://www.ncbi.nlm.nih.gov/pmc/articles/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 137, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "PMC6544545", "realUrl" : "http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544545", "published" : true, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 1301944, "link" : "/api/publicationidentifier/1301944", "label" : "SZTE Publicatio: 13551", "source" : { "otype" : "SwordSource", "mtid" : 90, "link" : "/api/publicationsource/90", "label" : "SZTE Publicatio", "type" : { "otype" : "PublicationSourceType", "mtid" : 10007, "link" : "/api/publicationsourcetype/10007", "label" : "Repozitórium", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "SZTE Publicatio", "nameEng" : "SZTE Publicatio", "linkPattern" : "http://publicatio.bibl.u-szeged.hu/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 90, "snippet" : true }, "oaType" : "GREEN", "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "13551", "realUrl" : "http://publicatio.bibl.u-szeged.hu/13551", "published" : false, "oldId" : 1791520, "snippet" : true } ], "journal" : { "otype" : "Journal", "mtid" : 10069420, "link" : "/api/journal/10069420", "label" : "NATURE MICROBIOLOGY 2058-5276 2058-5276", "pIssn" : "2058-5276", "eIssn" : "2058-5276", "reviewType" : "REVIEWED", "noIF" : false, "sciIndexed" : true, "scopusIndexed" : true, "lang" : "FOREIGN", "hungarian" : false, "published" : true, "oldId" : 10069420, "snippet" : true }, "volume" : "3", "issue" : "6", "firstPage" : "718", "lastPage" : "731", "firstPageOrInternalIdForSort" : "718", "pageLength" : 14, "publishedYear" : 2018, "abstractText" : "Antimicrobial peptides are promising alternative antimicrobial agents. However, little is known about whether resistance to small-molecule antibiotics leads to cross-resistance (decreased sensitivity) or collateral sensitivity (increased sensitivity) to antimicrobial peptides. We systematically addressed this question by studying the susceptibilities of a comprehensive set of 60 antibiotic-resistant Escherichia coli strains towards 24 antimicrobial peptides. Strikingly, antibiotic-resistant bacteria show a high frequency of collateral sensitivity to antimicrobial peptides, whereas cross-resistance is relatively rare. We identify clinically relevant multidrug-resistance mutations that increase bacterial sensitivity to antimicrobial peptides. Collateral sensitivity in multidrug-resistant bacteria arises partly through regulatory changes shaping the lipopolysaccharide composition of the bacterial outer membrane. These advances allow the identification of antimicrobial peptide-antibiotic combinations that enhance antibiotic activity against multidrug-resistant bacteria and slow down de novo evolution of resistance. In particular, when co-administered as an adjuvant, the antimicrobial peptide glycine-leucine-amide caused up to 30-fold decrease in the antibiotic resistance level of resistant bacteria. Our work provides guidelines for the development of efficient peptide-based therapies of antibiotic-resistant infections.", "subjects" : [ { "otype" : "Classification", "mtid" : 12125, "link" : "/api/classification/12125", "label" : "Basic medicine", "published" : true, "snippet" : true }, { "otype" : "Classification", "mtid" : 10545, "link" : "/api/classification/10545", "label" : "Biological sciences", "published" : true, "snippet" : true }, { "otype" : "Classification", "mtid" : 12215, "link" : "/api/classification/12215", "label" : "Clinical medicine", "published" : true, "snippet" : true } ], "digital" : null, "printed" : null, "sourceYear" : 2018, "packet" : "142040", "foreignEdition" : true, "foreignLanguage" : true, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : true, "missingAuthor" : false, "oaType" : "GREEN", "oaTypeDisp" : "GREEN", "oaCheckDate" : "2024-03-25", "oaFree" : true, "oaLink" : "http://publicatio.bibl.u-szeged.hu/13551", "citationCount" : 275, "citationCountUnpublished" : 0, "citationCountWoOther" : 260, "independentCitCountWoOther" : 243, "nationalOriginCitationCount" : 17, "foreignEditionCitationCount" : 259, "doiCitationCount" : 258, "wosCitationCount" : 239, "scopusCitationCount" : 247, "wosScopusCitationCount" : 249, "wosScopusCitationCountWoOther" : 249, "wosScopusIndependentCitationCount" : 233, "wosScopusIndependentCitationCountWoOther" : 233, "independentCitationCount" : 257, "selfCitationCount" : 18, "unhandledCitationCount" : 0, "citingPubCount" : 275, "independentCitingPubCount" : 257, "citingPubCountWoOther" : 260, "independentCitingPubCountWoOther" : 243, "unhandledCitingPubCount" : 0, "citedPubCount" : 9, "citedCount" : 9, "ratings" : [ { "otype" : "SjrRating", "mtid" : 10743254, "link" : "/api/sjrrating/10743254", "label" : "sjr:D1 (2018) Scopus - Applied Microbiology and Biotechnology NATURE MICROBIOLOGY 2058-5276", "listPos" : 2, "rankValue" : 0.1, "type" : "journal", "ratingType" : { "otype" : "RatingType", "mtid" : 10002, "link" : "/api/ratingtype/10002", "label" : "sjr", "code" : "sjr", "published" : true, "snippet" : true }, "subject" : { "otype" : "ClassificationExternal", "mtid" : 2402, "link" : "/api/classificationexternal/2402", "label" : "Scopus - Applied Microbiology and Biotechnology", "published" : true, "oldId" : 2402, "snippet" : true }, "ranking" : "D1", "calculation" : "DIRECT", "published" : true, "snippet" : true } ], "ratingsForSort" : "D1", "hasCitationDuplums" : false, "inSelectedPubs" : "10033114,10039902,10027825,10032015,10028887,10009032,10001168,10025198,10036222", "userChangeableUntil" : "2019-01-27T13:00:18.982+0000", "publishDate" : "2018-05-30T11:44:17.000+0000", "directInstitutesForSort" : "Biofizikai Intézet (HRN SZBK); Biokémiai Intézet (HRN SZBK); Gyógyszeranalitikai Intézet (SZTE / GYTK); Klinikai Mikrobiológiai Diagnosztikai Intézet (SZTE / ÁOK)", "ownerAuthorCount" : 25, "ownerInstituteCount" : 64, "directInstituteCount" : 4, "authorCount" : 25, "contributorCount" : 0, "hasQualityFactor" : true, "tempLockerIds" : [ 10003141 ], "link" : "/api/publication/3378998", "label" : "Lazar V et al. Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides. (2018) NATURE MICROBIOLOGY 2058-5276 2058-5276 3 6 718-731", "template" : "